588898:BB347 RS07970
gene id: 588898:BB347_RS07970
uniprot id: A0A1N7BQQ9
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS11495
gene id: 588898:BB347_RS11495
uniprot id: A0A1N7D3E4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

588898:BB347 RS09770
gene id: 588898:BB347_RS09770
uniprot id: A0A1N7CFX6
names: Similarity
messages: Belongs to the UPF0284 family.

588898:BB347 RS08260
gene id: 588898:BB347_RS08260
uniprot id: A0A1N7BV72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

588898:BB347 RS07295
gene id: 588898:BB347_RS07295
uniprot id: A0A1P8RCR0
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS04495
gene id: 588898:BB347_RS04495
uniprot id: A0A1N6XJU5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

588898:BB347 RS05075
gene id: 588898:BB347_RS05075
uniprot id: A0A1N6X5L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS07325
gene id: 588898:BB347_RS07325
uniprot id: A0A1N7E9K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS05795
gene id: 588898:BB347_RS05795
uniprot id: A0A1N7DU38
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

588898:BB347 RS09785
gene id: 588898:BB347_RS09785
uniprot id: A0A1N7CGD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

588898:BB347 RS00070
gene id: 588898:BB347_RS00070
uniprot id: A0A1N7A6Z9
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS07920
gene id: 588898:BB347_RS07920
uniprot id: A0A1N7BPR5
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS14295
gene id: 588898:BB347_RS14295
uniprot id: A0A1N7EVM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

588898:BB347 RS15945
gene id: 588898:BB347_RS15945
uniprot id: A0A1N7AHG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

588898:BB347 RS07095
gene id: 588898:BB347_RS07095
uniprot id: A0A1N7E7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS04490
gene id: 588898:BB347_RS04490
uniprot id: A0A1N6XJV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

588898:BB347 RS16470
gene id: 588898:BB347_RS16470
uniprot id: A0A1N7FIV8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS18125
gene id: 588898:BB347_RS18125
uniprot id: A0A1N7G125
names: Similarity
messages: Belongs to the TFIIB family.

588898:BB347 RS13190
gene id: 588898:BB347_RS13190
uniprot id: A0A1N7F280
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

588898:BB347 RS03255
gene id: 588898:BB347_RS03255
uniprot id: A0A1N6YC21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

588898:BB347 RS16405
gene id: 588898:BB347_RS16405
uniprot id: A0A1N7A9C9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

588898:BB347 RS15710
gene id: 588898:BB347_RS15710
uniprot id: A0A1N7AM12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

588898:BB347 RS07695
gene id: 588898:BB347_RS07695
uniprot id: A0A1N7EDA7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

588898:BB347 RS12245
gene id: 588898:BB347_RS12245
uniprot id: A0A1N7FPV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

588898:BB347 RS11285
gene id: 588898:BB347_RS11285
uniprot id: A0A1N7D105
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

588898:BB347 RS15935
gene id: 588898:BB347_RS15935
uniprot id: A0A1N7AHD4
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

588898:BB347 RS07355
gene id: 588898:BB347_RS07355
uniprot id: A0A1N7EA49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

588898:BB347 RS15460
gene id: 588898:BB347_RS15460
uniprot id: A0A1N7EKD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

588898:BB347 RS04480
gene id: 588898:BB347_RS04480
uniprot id: A0A1N6XK81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

588898:BB347 RS03380
gene id: 588898:BB347_RS03380
uniprot id: A0A1N6Y9G6
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS05990
gene id: 588898:BB347_RS05990
uniprot id: A0A1N7DW01
names: Caution
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS06350
gene id: 588898:BB347_RS06350
uniprot id: A0A1N7E033
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

588898:BB347 RS10310
gene id: 588898:BB347_RS10310
uniprot id: A0A1P8RI28
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS14940
gene id: 588898:BB347_RS14940
uniprot id: A0A1N7EPU0
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS16540
gene id: 588898:BB347_RS16540
uniprot id: A0A1N7FJF3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

588898:BB347 RS10780
gene id: 588898:BB347_RS10780
uniprot id: A0A1N7CUG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofG family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

588898:BB347 RS04215
gene id: 588898:BB347_RS04215
uniprot id: A0A1N6XQX9
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS09840
gene id: 588898:BB347_RS09840
uniprot id: A0A1N7CGP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

588898:BB347 RS13825
gene id: 588898:BB347_RS13825
uniprot id: A0A1N7F8E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

588898:BB347 RS12100
gene id: 588898:BB347_RS12100
uniprot id: A0A1N7G965
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

588898:BB347 RS03645
gene id: 588898:BB347_RS03645
uniprot id: A0A1N6Y4R6
names: Similarity
messages: Belongs to the UPF0440 family.

588898:BB347 RS06780
gene id: 588898:BB347_RS06780
uniprot id: A0A1N7E3Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

588898:BB347 RS02470
gene id: 588898:BB347_RS02470
uniprot id: A0A1N6YU09
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS06930
gene id: 588898:BB347_RS06930
uniprot id: A0A1N7E5E8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

588898:BB347 RS10185
gene id: 588898:BB347_RS10185
uniprot id: A0A1N7CLI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

588898:BB347 RS12155
gene id: 588898:BB347_RS12155
uniprot id: A0A1N7FPN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

588898:BB347 RS02185
gene id: 588898:BB347_RS02185
uniprot id: A0A1N6YZ34
names: Similarity
messages: Belongs to the Nudix hydrolase family.

588898:BB347 RS06635
gene id: 588898:BB347_RS06635
uniprot id: A0A1N7E2B5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

588898:BB347 RS12565
gene id: 588898:BB347_RS12565
uniprot id: A0A1N7FS00
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS03710
gene id: 588898:BB347_RS03710
uniprot id: A0A1N6Y308
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

588898:BB347 RS06305
gene id: 588898:BB347_RS06305
uniprot id: A0A1N7DZH5
names: Similarity
messages: Belongs to the LarC family.

588898:BB347 RS04510
gene id: 588898:BB347_RS04510
uniprot id: A0A1N6XJ49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

588898:BB347 RS06620
gene id: 588898:BB347_RS06620
uniprot id: A0A1N7E2E7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

588898:BB347 RS15210
gene id: 588898:BB347_RS15210
uniprot id: A0A1N7EMJ9
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 zinc ion.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

588898:BB347 RS15030
gene id: 588898:BB347_RS15030
uniprot id: A0A1N7EP59
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

588898:BB347 RS16050
gene id: 588898:BB347_RS16050
uniprot id: A0A1N7AFD8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

588898:BB347 RS15635
gene id: 588898:BB347_RS15635
uniprot id: A0A1N7AN96
names: Similarity
messages: Belongs to the NAD synthetase family.

588898:BB347 RS04780
gene id: 588898:BB347_RS04780
uniprot id: A0A1N6XCT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

588898:BB347 RS14140
gene id: 588898:BB347_RS14140
uniprot id: A0A1N7FAQ7
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS13685
gene id: 588898:BB347_RS13685
uniprot id: A0A1N7F6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

588898:BB347 RS15110
gene id: 588898:BB347_RS15110
uniprot id: A0A1N7ENI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

588898:BB347 RS00370
gene id: 588898:BB347_RS00370
uniprot id: A0A1N7A180
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

588898:BB347 RS16040
gene id: 588898:BB347_RS16040
uniprot id: A0A1N7AFT2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

588898:BB347 RS15385
gene id: 588898:BB347_RS15385
uniprot id: A0A1N7EL44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

588898:BB347 RS02420
gene id: 588898:BB347_RS02420
uniprot id: A0A1N6YUM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

588898:BB347 RS16695
gene id: 588898:BB347_RS16695
uniprot id: A0A1N7FKN8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

588898:BB347 RS07490
gene id: 588898:BB347_RS07490
uniprot id: A0A1N7EB92
names: Similarity
messages: Belongs to the archease family.

588898:BB347 RS06595
gene id: 588898:BB347_RS06595
uniprot id: A0A1N7E255
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

588898:BB347 RS08550
gene id: 588898:BB347_RS08550
uniprot id: A0A1N7BYX1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

588898:BB347 RS01355
gene id: 588898:BB347_RS01355
uniprot id: A0A1N6ZFU3
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS02395
gene id: 588898:BB347_RS02395
uniprot id: A0A1P8RHG9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

588898:BB347 RS08810
gene id: 588898:BB347_RS08810
uniprot id: A0A1N7C2F0
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

588898:BB347 RS13245
gene id: 588898:BB347_RS13245
uniprot id: A0A1N7F2T4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

588898:BB347 RS01240
gene id: 588898:BB347_RS01240
uniprot id: A0A1N6ZI42
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

588898:BB347 RS07635
gene id: 588898:BB347_RS07635
uniprot id: A0A1N7ECZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

588898:BB347 RS10850
gene id: 588898:BB347_RS10850
uniprot id: A0A1N7CVR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

588898:BB347 RS02015
gene id: 588898:BB347_RS02015
uniprot id: A0A1N6Z2G1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

588898:BB347 RS16615
gene id: 588898:BB347_RS16615
uniprot id: A0A1N7FK07
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

588898:BB347 RS01560
gene id: 588898:BB347_RS01560
uniprot id: A0A1P8RHP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

588898:BB347 RS16080
gene id: 588898:BB347_RS16080
uniprot id: A0A1N7AFB9
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

588898:BB347 RS09820
gene id: 588898:BB347_RS09820
uniprot id: A0A1N7CGJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane
messages: S-layer

588898:BB347 RS15800
gene id: 588898:BB347_RS15800
uniprot id: A0A1N7AK88
names: Similarity
messages: Belongs to the PDCD5 family.

588898:BB347 RS15140
gene id: 588898:BB347_RS15140
uniprot id: A0A1N7ENP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

588898:BB347 RS03040
gene id: 588898:BB347_RS03040
uniprot id: A0A1N6YGL5
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS07860
gene id: 588898:BB347_RS07860
uniprot id: A0A1N7BP95
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

588898:BB347 RS08800
gene id: 588898:BB347_RS08800
uniprot id: A0A1N7C296
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

588898:BB347 RS05950
gene id: 588898:BB347_RS05950
uniprot id: A0A1N7DVQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

588898:BB347 RS08385
gene id: 588898:BB347_RS08385
uniprot id: A0A1N7BX05
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS03675
gene id: 588898:BB347_RS03675
uniprot id: A0A1N6Y417
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

588898:BB347 RS14350
gene id: 588898:BB347_RS14350
uniprot id: A0A1N7EV10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

588898:BB347 RS08085
gene id: 588898:BB347_RS08085
uniprot id: A0A1N7BSD0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

588898:BB347 RS14890
gene id: 588898:BB347_RS14890
uniprot id: A0A1N7EQ43
names: Similarity
messages: Belongs to the peptidase S9C family.

588898:BB347 RS11195
gene id: 588898:BB347_RS11195
uniprot id: A0A1N7D0J0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

588898:BB347 RS06130
gene id: 588898:BB347_RS06130
uniprot id: A0A1N7DXH1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

588898:BB347 RS06575
gene id: 588898:BB347_RS06575
uniprot id: A0A1N7E1X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

588898:BB347 RS15075
gene id: 588898:BB347_RS15075
uniprot id: A0A1N7ENW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

588898:BB347 RS01650
gene id: 588898:BB347_RS01650
uniprot id: A0A1N6Z9B6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS17870
gene id: 588898:BB347_RS17870
uniprot id: A0A1N7FYI5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

588898:BB347 RS08885
gene id: 588898:BB347_RS08885
uniprot id: A0A1N7C3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

588898:BB347 RS06970
gene id: 588898:BB347_RS06970
uniprot id: A0A1N7E632
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

588898:BB347 RS09605
gene id: 588898:BB347_RS09605
uniprot id: A0A1N7CDQ1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

588898:BB347 RS02380
gene id: 588898:BB347_RS02380
uniprot id: A0A1N6YW46
names: Similarity
messages: Belongs to the phosphohexose mutase family.

588898:BB347 RS04390
gene id: 588898:BB347_RS04390
uniprot id: A0A1N6XM79
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

588898:BB347 RS08465
gene id: 588898:BB347_RS08465
uniprot id: A0A1N7BXZ3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

588898:BB347 RS08285
gene id: 588898:BB347_RS08285
uniprot id: A0A1N7BVC7
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS11295
gene id: 588898:BB347_RS11295
uniprot id: A0A1N7D138
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

588898:BB347 RS13830
gene id: 588898:BB347_RS13830
uniprot id: A0A1N7F861
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

588898:BB347 RS03090
gene id: 588898:BB347_RS03090
uniprot id: A0A1N6YFH8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

588898:BB347 RS15805
gene id: 588898:BB347_RS15805
uniprot id: A0A1P8RI23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

588898:BB347 RS06345
gene id: 588898:BB347_RS06345
uniprot id: A0A1N7E014
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS13040
gene id: 588898:BB347_RS13040
uniprot id: A0A1N7F0I6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

588898:BB347 RS06630
gene id: 588898:BB347_RS06630
uniprot id: A0A1N7E2A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

588898:BB347 RS03245
gene id: 588898:BB347_RS03245
uniprot id: A0A1N6YC91
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS04420
gene id: 588898:BB347_RS04420
uniprot id: A0A1N6XLM1
names: Similarity
messages: Belongs to the GARS family.

588898:BB347 RS00410
gene id: 588898:BB347_RS00410
uniprot id: A0A1N7A0F2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

588898:BB347 RS06150
gene id: 588898:BB347_RS06150
uniprot id: A0A1N7DXM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

588898:BB347 RS11730
gene id: 588898:BB347_RS11730
uniprot id: A0A1N7D5W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

588898:BB347 RS03765
gene id: 588898:BB347_RS03765
uniprot id: A0A1N6Y1U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

588898:BB347 RS03355
gene id: 588898:BB347_RS03355
uniprot id: A0A1N6YA55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

588898:BB347 RS04400
gene id: 588898:BB347_RS04400
uniprot id: A0A1N6XM24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS12170
gene id: 588898:BB347_RS12170
uniprot id: A0A1N7FPK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

588898:BB347 RS05260
gene id: 588898:BB347_RS05260
uniprot id: A0A1N7DMW4
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

588898:BB347 RS08820
gene id: 588898:BB347_RS08820
uniprot id: A0A1N7C2X3
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS07700
gene id: 588898:BB347_RS07700
uniprot id: A0A1N7EDI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

588898:BB347 RS01540
gene id: 588898:BB347_RS01540
uniprot id: A0A1N6ZBN3
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

588898:BB347 RS04905
gene id: 588898:BB347_RS04905
uniprot id: A0A1N6X9H7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

588898:BB347 RS13170
gene id: 588898:BB347_RS13170
uniprot id: A0A1P8RHY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homodimer.

588898:BB347 RS16300
gene id: 588898:BB347_RS16300
uniprot id: A0A1N7ABA7
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS16800
gene id: 588898:BB347_RS16800
uniprot id: A0A1N7FLD8
names: Similarity
messages: Belongs to the peptidase M24B family.

588898:BB347 RS12550
gene id: 588898:BB347_RS12550
uniprot id: A0A1N7FRX7
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

588898:BB347 RS05375
gene id: 588898:BB347_RS05375
uniprot id: A0A1N7DPQ3
names: Similarity
messages: Belongs to the Nth/MutY family.

588898:BB347 RS04675
gene id: 588898:BB347_RS04675
uniprot id: A0A1N6XF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

588898:BB347 RS05390
gene id: 588898:BB347_RS05390
uniprot id: A0A1N7DPD8
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

588898:BB347 RS04455
gene id: 588898:BB347_RS04455
uniprot id: A0A1N6XKW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

588898:BB347 RS12815
gene id: 588898:BB347_RS12815
uniprot id: A0A1N7FU12
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

588898:BB347 RS04825
gene id: 588898:BB347_RS04825
uniprot id: A0A1N6XBD1
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS15405
gene id: 588898:BB347_RS15405
uniprot id: A0A1N7EKU2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS10070
gene id: 588898:BB347_RS10070
uniprot id: A0A1N7CK49
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

588898:BB347 RS05530
gene id: 588898:BB347_RS05530
uniprot id: A0A1N7DRD6
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS00500
gene id: 588898:BB347_RS00500
uniprot id: A0A1N6ZYQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

588898:BB347 RS10120
gene id: 588898:BB347_RS10120
uniprot id: A0A1N7CKD8
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS15700
gene id: 588898:BB347_RS15700
uniprot id: A0A1N7AMB0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS06700
gene id: 588898:BB347_RS06700
uniprot id: A0A1N7E344
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

588898:BB347 RS07985
gene id: 588898:BB347_RS07985
uniprot id: A0A1N7BQL9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

588898:BB347 RS11055
gene id: 588898:BB347_RS11055
uniprot id: A0A1N7CYJ0
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

588898:BB347 RS05960
gene id: 588898:BB347_RS05960
uniprot id: A0A1N7DVT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

588898:BB347 RS06310
gene id: 588898:BB347_RS06310
uniprot id: A0A1N7DZF6
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

588898:BB347 RS11005
gene id: 588898:BB347_RS11005
uniprot id: A0A1N7CXP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

588898:BB347 RS17405
gene id: 588898:BB347_RS17405
uniprot id: A0A1N7GA98
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

588898:BB347 RS15260
gene id: 588898:BB347_RS15260
uniprot id: A0A1N7EM28
names: Similarity
messages: Belongs to the AHA1 family.

588898:BB347 RS08765
gene id: 588898:BB347_RS08765
uniprot id: A0A1N7C1V4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

588898:BB347 RS14615
gene id: 588898:BB347_RS14615
uniprot id: A0A1N7ES94
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS10755
gene id: 588898:BB347_RS10755
uniprot id: A0A1P8REV1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

588898:BB347 RS17495
gene id: 588898:BB347_RS17495
uniprot id: A0A1N7GAJ5
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS10115
gene id: 588898:BB347_RS10115
uniprot id: A0A1N7CKF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

588898:BB347 RS06900
gene id: 588898:BB347_RS06900
uniprot id: A0A1N7E539
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS01280
gene id: 588898:BB347_RS01280
uniprot id: A0A1N6ZHA4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS12535
gene id: 588898:BB347_RS12535
uniprot id: A0A1N7FRR3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

588898:BB347 RS16635
gene id: 588898:BB347_RS16635
uniprot id: A0A1N7FK35
names: Subcellular Location Annotation
messages: Cytoplasm

588898:BB347 RS06690
gene id: 588898:BB347_RS06690
uniprot id: A0A1N7E2Y5
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS13770
gene id: 588898:BB347_RS13770
uniprot id: A0A1N7F7L1
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS05350
gene id: 588898:BB347_RS05350
uniprot id: A0A1N7DPA4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

588898:BB347 RS16575
gene id: 588898:BB347_RS16575
uniprot id: A0A1N7FJH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

588898:BB347 RS04700
gene id: 588898:BB347_RS04700
uniprot id: A0A1N6XEF2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

588898:BB347 RS04810
gene id: 588898:BB347_RS04810
uniprot id: A0A1N6XBN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

588898:BB347 RS07680
gene id: 588898:BB347_RS07680
uniprot id: A0A1N7EDJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

588898:BB347 RS15415
gene id: 588898:BB347_RS15415
uniprot id: A0A1P8RI39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

588898:BB347 RS09780
gene id: 588898:BB347_RS09780
uniprot id: A0A1N7CGE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

588898:BB347 RS14835
gene id: 588898:BB347_RS14835
uniprot id: A0A1N7EQD4
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS01855
gene id: 588898:BB347_RS01855
uniprot id: A0A1N6Z560
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

588898:BB347 RS02135
gene id: 588898:BB347_RS02135
uniprot id: A0A1P8R9Z9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

588898:BB347 RS07165
gene id: 588898:BB347_RS07165
uniprot id: A0A1N7E7U6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

588898:BB347 RS06645
gene id: 588898:BB347_RS06645
uniprot id: A0A1N7E2K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

588898:BB347 RS15965
gene id: 588898:BB347_RS15965
uniprot id: A0A1N7AHB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

588898:BB347 RS17875
gene id: 588898:BB347_RS17875
uniprot id: A0A1N7FYU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

588898:BB347 RS03600
gene id: 588898:BB347_RS03600
uniprot id: A0A1N6Y5L1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

588898:BB347 RS09315
gene id: 588898:BB347_RS09315
uniprot id: A0A1N7C9G2
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS09615
gene id: 588898:BB347_RS09615
uniprot id: A0A1N7CDS2
names: Similarity
messages: Belongs to the peptidase S8 family.

588898:BB347 RS13690
gene id: 588898:BB347_RS13690
uniprot id: A0A1N7F6X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS13795
gene id: 588898:BB347_RS13795
uniprot id: A0A1N7F7T4
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS00740
gene id: 588898:BB347_RS00740
uniprot id: A0A1N6ZU30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

588898:BB347 RS17510
gene id: 588898:BB347_RS17510
uniprot id: A0A1N7GAY3
names: Function
messages: Part of a potassium transport system.

588898:BB347 RS06810
gene id: 588898:BB347_RS06810
uniprot id: A0A1N7E4D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

588898:BB347 RS01275
gene id: 588898:BB347_RS01275
uniprot id: A0A1N6ZHN0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS09230
gene id: 588898:BB347_RS09230
uniprot id: A0A1P8RHQ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS08660
gene id: 588898:BB347_RS08660
uniprot id: A0A1N7C0D9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

588898:BB347 RS12855
gene id: 588898:BB347_RS12855
uniprot id: A0A1N7FU73
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS05575
gene id: 588898:BB347_RS05575
uniprot id: A0A1N7DRR9
names: Subcellular Location Annotation
messages: Cell membrane

588898:BB347 RS03560
gene id: 588898:BB347_RS03560
uniprot id: A0A1N6Y6D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

588898:BB347 RS05820
gene id: 588898:BB347_RS05820
uniprot id: A0A1N7DUB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

588898:BB347 RS18370
gene id: 588898:BB347_RS18370
uniprot id: A0A1N7G2G6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

588898:BB347 RS04430
gene id: 588898:BB347_RS04430
uniprot id: A0A1N6XL97
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS13460
gene id: 588898:BB347_RS13460
uniprot id: A0A1N7F517
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

588898:BB347 RS11715
gene id: 588898:BB347_RS11715
uniprot id: A0A1N7D5U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS06660
gene id: 588898:BB347_RS06660
uniprot id: A0A1N7E2R4
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS17880
gene id: 588898:BB347_RS17880
uniprot id: A0A1N7FYV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

588898:BB347 RS00865
gene id: 588898:BB347_RS00865
uniprot id: A0A1N6ZRW5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS06570
gene id: 588898:BB347_RS06570
uniprot id: A0A1N7E1X4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

588898:BB347 RS09670
gene id: 588898:BB347_RS09670
uniprot id: A0A1P8RDX4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS01370
gene id: 588898:BB347_RS01370
uniprot id: A0A1N6ZFE4
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

588898:BB347 RS07575
gene id: 588898:BB347_RS07575
uniprot id: A0A1N7EC58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

588898:BB347 RS04960
gene id: 588898:BB347_RS04960
uniprot id: A0A1N6X7X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

588898:BB347 RS12540
gene id: 588898:BB347_RS12540
uniprot id: A0A1N7FRN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS08025
gene id: 588898:BB347_RS08025
uniprot id: A0A1N7BRL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

588898:BB347 RS04835
gene id: 588898:BB347_RS04835
uniprot id: A0A1P8RHW4
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS06535
gene id: 588898:BB347_RS06535
uniprot id: A0A1N7E1H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

588898:BB347 RS12425
gene id: 588898:BB347_RS12425
uniprot id: A0A1N7FR33
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

588898:BB347 RS13450
gene id: 588898:BB347_RS13450
uniprot id: A0A1N7F4X9
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS17390
gene id: 588898:BB347_RS17390
uniprot id: A0A1N7FIK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

588898:BB347 RS00985
gene id: 588898:BB347_RS00985
uniprot id: A0A1N6ZNW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

588898:BB347 RS02230
gene id: 588898:BB347_RS02230
uniprot id: A0A1N6YYC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

588898:BB347 RS05135
gene id: 588898:BB347_RS05135
uniprot id: A0A1N6X400
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

588898:BB347 RS05275
gene id: 588898:BB347_RS05275
uniprot id: A0A1N7DN37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

588898:BB347 RS00940
gene id: 588898:BB347_RS00940
uniprot id: A0A1N6ZQJ2
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

588898:BB347 RS00130
gene id: 588898:BB347_RS00130
uniprot id: A0A1N7A5W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

588898:BB347 RS17150
gene id: 588898:BB347_RS17150
uniprot id: A0A1N7FGF0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

588898:BB347 RS03015
gene id: 588898:BB347_RS03015
uniprot id: A0A1N6YHH2
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

588898:BB347 RS05840
gene id: 588898:BB347_RS05840
uniprot id: A0A1N7DUA9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

588898:BB347 RS03955
gene id: 588898:BB347_RS03955
uniprot id: A0A1N6XX93
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

588898:BB347 RS13145
gene id: 588898:BB347_RS13145
uniprot id: A0A1N7F1N6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS12655
gene id: 588898:BB347_RS12655
uniprot id: A0A1N7FSV0
names: Subcellular Location Annotation
messages: Cytoplasm

588898:BB347 RS13555
gene id: 588898:BB347_RS13555
uniprot id: A0A1N7F5J6
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

588898:BB347 RS09575
gene id: 588898:BB347_RS09575
uniprot id: A0A1N7CDH6
names: Subunit
messages: Homotetramer.

588898:BB347 RS16885
gene id: 588898:BB347_RS16885
uniprot id: A0A1N7FLZ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS05005
gene id: 588898:BB347_RS05005
uniprot id: A0A1N6X6Z3
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

588898:BB347 RS04500
gene id: 588898:BB347_RS04500
uniprot id: A0A1N6XJK0
names: Similarity
messages: Belongs to the SDO1/SBDS family.

588898:BB347 RS02715
gene id: 588898:BB347_RS02715
uniprot id: A0A1N6YN41
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

588898:BB347 RS14610
gene id: 588898:BB347_RS14610
uniprot id: A0A1N7ESE0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

588898:BB347 RS14155
gene id: 588898:BB347_RS14155
uniprot id: A0A1N7FB80
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

588898:BB347 RS08570
gene id: 588898:BB347_RS08570
uniprot id: A0A1N7BZJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

588898:BB347 RS05425
gene id: 588898:BB347_RS05425
uniprot id: A0A1N7DPW6
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

588898:BB347 RS03855
gene id: 588898:BB347_RS03855
uniprot id: A0A1N6XZH9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

588898:BB347 RS08920
gene id: 588898:BB347_RS08920
uniprot id: A0A1N7C3U9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

588898:BB347 RS10665
gene id: 588898:BB347_RS10665
uniprot id: A0A1N7CSP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

588898:BB347 RS04985
gene id: 588898:BB347_RS04985
uniprot id: A0A1N6X7C0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

588898:BB347 RS17600
gene id: 588898:BB347_RS17600
uniprot id: A0A1N7GBB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

588898:BB347 RS11355
gene id: 588898:BB347_RS11355
uniprot id: A0A1N7D1V8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS13505
gene id: 588898:BB347_RS13505
uniprot id: A0A1N7F5A3
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.

588898:BB347 RS03725
gene id: 588898:BB347_RS03725
uniprot id: A0A1N6Y2Q1
names: Similarity
messages: Belongs to the DtxR/MntR family.

588898:BB347 RS00585
gene id: 588898:BB347_RS00585
uniprot id: A0A1N6ZX42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

588898:BB347 RS13090
gene id: 588898:BB347_RS13090
uniprot id: A0A1N7F140
names: Similarity
messages: Belongs to the HepT RNase toxin family.

588898:BB347 RS02940
gene id: 588898:BB347_RS02940
uniprot id: A0A1N6YIU8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

588898:BB347 RS06565
gene id: 588898:BB347_RS06565
uniprot id: A0A1N7E1V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

588898:BB347 RS15410
gene id: 588898:BB347_RS15410
uniprot id: A0A1N7EKZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

588898:BB347 RS03385
gene id: 588898:BB347_RS03385
uniprot id: A0A1N6Y9N1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

588898:BB347 RS16410
gene id: 588898:BB347_RS16410
uniprot id: A0A1N7A8U2
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

588898:BB347 RS07030
gene id: 588898:BB347_RS07030
uniprot id: A0A1N7E6K8
names: Subcellular Location Annotation
messages: Cell membrane

588898:BB347 RS06545
gene id: 588898:BB347_RS06545
uniprot id: A0A1N7E1W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

588898:BB347 RS08225
gene id: 588898:BB347_RS08225
uniprot id: A0A1N7BUC1
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS06910
gene id: 588898:BB347_RS06910
uniprot id: A0A1N7E542
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS08795
gene id: 588898:BB347_RS08795
uniprot id: A0A1N7C282
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS03810
gene id: 588898:BB347_RS03810
uniprot id: A0A1N6Y104
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

588898:BB347 RS06745
gene id: 588898:BB347_RS06745
uniprot id: A0A1N7E3H9
names: Similarity
messages: Belongs to the arginase family.

588898:BB347 RS03925
gene id: 588898:BB347_RS03925
uniprot id: A0A1N6XY45
names: Similarity
messages: Belongs to the UPF0212 family.

588898:BB347 RS05825
gene id: 588898:BB347_RS05825
uniprot id: A0A1N7DU85
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

588898:BB347 RS15790
gene id: 588898:BB347_RS15790
uniprot id: A0A1N7AK11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

588898:BB347 RS03535
gene id: 588898:BB347_RS03535
uniprot id: A0A1N6Y6T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

588898:BB347 RS09265
gene id: 588898:BB347_RS09265
uniprot id: A0A1N7C949
names: Similarity
messages: Belongs to the UPF0173 family.

588898:BB347 RS04120
gene id: 588898:BB347_RS04120
uniprot id: A0A1N6XTS3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

588898:BB347 RS16140
gene id: 588898:BB347_RS16140
uniprot id: A0A1N7AE77
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

588898:BB347 RS02340
gene id: 588898:BB347_RS02340
uniprot id: A0A1N6YWG2
names: Similarity
messages: Belongs to the peptidase S49 family.

588898:BB347 RS14695
gene id: 588898:BB347_RS14695
uniprot id: A0A1N7ERK9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

588898:BB347 RS01160
gene id: 588898:BB347_RS01160
uniprot id: A0A1N6ZK26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

588898:BB347 RS13725
gene id: 588898:BB347_RS13725
uniprot id: A0A1N7F743
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

588898:BB347 RS12215
gene id: 588898:BB347_RS12215
uniprot id: A0A1N7FPT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

588898:BB347 RS03205
gene id: 588898:BB347_RS03205
uniprot id: A0A1N6YDE9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

588898:BB347 RS15840
gene id: 588898:BB347_RS15840
uniprot id: A0A1N7AJJ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS10480
gene id: 588898:BB347_RS10480
uniprot id: A0A1N7CQS0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

588898:BB347 RS02985
gene id: 588898:BB347_RS02985
uniprot id: A0A1N6YHR1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS07565
gene id: 588898:BB347_RS07565
uniprot id: A0A1N7ECJ7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

588898:BB347 RS07120
gene id: 588898:BB347_RS07120
uniprot id: A0A1N7E7T5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS00785
gene id: 588898:BB347_RS00785
uniprot id: A0A1N6ZTA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

588898:BB347 RS17330
gene id: 588898:BB347_RS17330
uniprot id: A0A1N7FI71
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS09870
gene id: 588898:BB347_RS09870
uniprot id: A0A1N7CHE3
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS01300
gene id: 588898:BB347_RS01300
uniprot id: A0A1N6ZGW9
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

588898:BB347 RS05730
gene id: 588898:BB347_RS05730
uniprot id: A0A1N7DT31
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS07885
gene id: 588898:BB347_RS07885
uniprot id: A0A1N7BP73
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

588898:BB347 RS06025
gene id: 588898:BB347_RS06025
uniprot id: A0A1N7DWB7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

588898:BB347 RS04205
gene id: 588898:BB347_RS04205
uniprot id: A0A1P8RBH8
names: Similarity
messages: Belongs to the Dps family.

588898:BB347 RS06740
gene id: 588898:BB347_RS06740
uniprot id: A0A1N7E3G4
names: Subcellular Location Annotation
messages: Cytoplasm

588898:BB347 RS05875
gene id: 588898:BB347_RS05875
uniprot id: A0A1N7DUW3
names: Similarity
messages: Belongs to the AOR/FOR family.

588898:BB347 RS04025
gene id: 588898:BB347_RS04025
uniprot id: A0A1N6XVS3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS14865
gene id: 588898:BB347_RS14865
uniprot id: A0A1P8RI37
names: Similarity
messages: Belongs to the IMPACT family.

588898:BB347 RS15955
gene id: 588898:BB347_RS15955
uniprot id: A0A1N7AHA7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

588898:BB347 RS14645
gene id: 588898:BB347_RS14645
uniprot id: A0A1N7ESB8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

588898:BB347 RS15745
gene id: 588898:BB347_RS15745
uniprot id: A0A1P8RH19
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

588898:BB347 RS04640
gene id: 588898:BB347_RS04640
uniprot id: A0A1N6XG52
names: Similarity
messages: Belongs to the UPF0179 family.

588898:BB347 RS06625
gene id: 588898:BB347_RS06625
uniprot id: A0A1N7E298
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

588898:BB347 RS07380
gene id: 588898:BB347_RS07380
uniprot id: A0A1N7EAI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

588898:BB347 RS03000
gene id: 588898:BB347_RS03000
uniprot id: A0A1N6YHT0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

588898:BB347 RS15900
gene id: 588898:BB347_RS15900
uniprot id: A0A1N7AI81
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

588898:BB347 RS15545
gene id: 588898:BB347_RS15545
uniprot id: A0A1N7AQ42
names: Similarity
messages: Belongs to the thioesterase PaaI family.

588898:BB347 RS05885
gene id: 588898:BB347_RS05885
uniprot id: A0A1N7DV16
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

588898:BB347 RS06220
gene id: 588898:BB347_RS06220
uniprot id: A0A1N7DYH6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

588898:BB347 RS01715
gene id: 588898:BB347_RS01715
uniprot id: A0A1N6Z7V2
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS12510
gene id: 588898:BB347_RS12510
uniprot id: A0A1N7FRG0
names: Subcellular Location Annotation
messages: Nucleus

588898:BB347 RS15440
gene id: 588898:BB347_RS15440
uniprot id: A0A1N7EKQ5
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

588898:BB347 RS06035
gene id: 588898:BB347_RS06035
uniprot id: A0A1N7DWH2
names: Similarity
messages: Belongs to the TPP enzyme family.

588898:BB347 RS06895
gene id: 588898:BB347_RS06895
uniprot id: A0A1N7E568
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

588898:BB347 RS17380
gene id: 588898:BB347_RS17380
uniprot id: A0A1N7FIQ9
names: Similarity
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.

588898:BB347 RS00485
gene id: 588898:BB347_RS00485
uniprot id: A0A1N6ZYX9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

588898:BB347 RS10145
gene id: 588898:BB347_RS10145
uniprot id: A0A1N7CKY0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

588898:BB347 RS13670
gene id: 588898:BB347_RS13670
uniprot id: A0A1N7F6J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

588898:BB347 RS08420
gene id: 588898:BB347_RS08420
uniprot id: A0A1N7BXQ9
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

588898:BB347 RS02660
gene id: 588898:BB347_RS02660
uniprot id: A0A1P8RHM5
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

588898:BB347 RS03435
gene id: 588898:BB347_RS03435
uniprot id: A0A1N6Y8G4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

588898:BB347 RS15185
gene id: 588898:BB347_RS15185
uniprot id: A0A1N7ENB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

588898:BB347 RS17285
gene id: 588898:BB347_RS17285
uniprot id: A0A1N7FI12
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

588898:BB347 RS01170
gene id: 588898:BB347_RS01170
uniprot id: A0A1N6ZJH9
names: Similarity
messages: Belongs to the TrpC family.

588898:BB347 RS11060
gene id: 588898:BB347_RS11060
uniprot id: A0A1N7CY93
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

588898:BB347 RS02140
gene id: 588898:BB347_RS02140
uniprot id: A0A1N6Z038
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS01930
gene id: 588898:BB347_RS01930
uniprot id: A0A1N6Z449
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS03415
gene id: 588898:BB347_RS03415
uniprot id: A0A1N6Y8L7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

588898:BB347 RS11415
gene id: 588898:BB347_RS11415
uniprot id: A0A1N7D2K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS15435
gene id: 588898:BB347_RS15435
uniprot id: A0A1N7EKG9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

588898:BB347 RS01495
gene id: 588898:BB347_RS01495
uniprot id: A0A1N6ZCH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

588898:BB347 RS00545
gene id: 588898:BB347_RS00545
uniprot id: A0A1N6ZXP5
names: Similarity
messages: Belongs to the AOR/FOR family.

588898:BB347 RS05210
gene id: 588898:BB347_RS05210
uniprot id: A0A1N7DMD9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

588898:BB347 RS05255
gene id: 588898:BB347_RS05255
uniprot id: A0A1N7DN36
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

588898:BB347 RS06600
gene id: 588898:BB347_RS06600
uniprot id: A0A1N7E247
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

588898:BB347 RS12560
gene id: 588898:BB347_RS12560
uniprot id: A0A1N7FRX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

588898:BB347 RS07180
gene id: 588898:BB347_RS07180
uniprot id: A0A1N7E809
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS15160
gene id: 588898:BB347_RS15160
uniprot id: A0A1N7EN08
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

588898:BB347 RS06485
gene id: 588898:BB347_RS06485
uniprot id: A0A1N7E117
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

588898:BB347 RS05675
gene id: 588898:BB347_RS05675
uniprot id: A0A1N7DT61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

588898:BB347 RS14000
gene id: 588898:BB347_RS14000
uniprot id: A0A1N7F9P4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

588898:BB347 RS15425
gene id: 588898:BB347_RS15425
uniprot id: A0A1N7EKL8
names: Similarity
messages: Belongs to the MoaB/Mog family.

588898:BB347 RS13415
gene id: 588898:BB347_RS13415
uniprot id: A0A1N7F4B1
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

588898:BB347 RS00135
gene id: 588898:BB347_RS00135
uniprot id: A0A1N7A5V6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

588898:BB347 RS03935
gene id: 588898:BB347_RS03935
uniprot id: A0A1N6XY50
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

588898:BB347 RS06890
gene id: 588898:BB347_RS06890
uniprot id: A0A1N7E515
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

588898:BB347 RS07975
gene id: 588898:BB347_RS07975
uniprot id: A0A1N7BQM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS14825
gene id: 588898:BB347_RS14825
uniprot id: A0A1N7EQF2
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS10745
gene id: 588898:BB347_RS10745
uniprot id: A0A1N7CUI0
names: Similarity
messages: Belongs to the UPF0215 family.

588898:BB347 RS07545
gene id: 588898:BB347_RS07545
uniprot id: A0A1N7EBV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

588898:BB347 RS08365
gene id: 588898:BB347_RS08365
uniprot id: A0A1N7BWQ7
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

588898:BB347 RS08050
gene id: 588898:BB347_RS08050
uniprot id: A0A1N7BS60
names: Similarity
messages: Belongs to the UPF0212 family.

588898:BB347 RS00955
gene id: 588898:BB347_RS00955
uniprot id: A0A1N6ZPY5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS06335
gene id: 588898:BB347_RS06335
uniprot id: A0A1N7DZR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS11385
gene id: 588898:BB347_RS11385
uniprot id: A0A1N7D2D2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS15255
gene id: 588898:BB347_RS15255
uniprot id: A0A1N7EM62
names: Similarity
messages: Belongs to the AHA1 family.

588898:BB347 RS10615
gene id: 588898:BB347_RS10615
uniprot id: A0A1N7CSC4
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS03295
gene id: 588898:BB347_RS03295
uniprot id: A0A1N6YBI2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

588898:BB347 RS07960
gene id: 588898:BB347_RS07960
uniprot id: A0A1N7BQ68
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

588898:BB347 RS16430
gene id: 588898:BB347_RS16430
uniprot id: A0A1N7A8P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

588898:BB347 RS00755
gene id: 588898:BB347_RS00755
uniprot id: A0A1N6ZTQ5
names: Similarity
messages: Belongs to the peptidase S1C family.

588898:BB347 RS02235
gene id: 588898:BB347_RS02235
uniprot id: A0A1N6YY94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

588898:BB347 RS02250
gene id: 588898:BB347_RS02250
uniprot id: A0A1N6YXU1
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS14675
gene id: 588898:BB347_RS14675
uniprot id: A0A1N7ERR6
names: Similarity
messages: Belongs to the threonine synthase family.

588898:BB347 RS00335
gene id: 588898:BB347_RS00335
uniprot id: A0A1N7A1N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

588898:BB347 RS08850
gene id: 588898:BB347_RS08850
uniprot id: A0A1N7C2W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

588898:BB347 RS11335
gene id: 588898:BB347_RS11335
uniprot id: A0A1N7D1X4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS06770
gene id: 588898:BB347_RS06770
uniprot id: A0A1N7E457
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

588898:BB347 RS06680
gene id: 588898:BB347_RS06680
uniprot id: A0A1N7E313
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

588898:BB347 RS12240
gene id: 588898:BB347_RS12240
uniprot id: A0A1N7FQ91
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

588898:BB347 RS00540
gene id: 588898:BB347_RS00540
uniprot id: A0A1N6ZXL4
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS14845
gene id: 588898:BB347_RS14845
uniprot id: A0A1N7EQB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

588898:BB347 RS08965
gene id: 588898:BB347_RS08965
uniprot id: A0A1N7C4I9
names: Similarity
messages: Belongs to the RutC family.

588898:BB347 RS07410
gene id: 588898:BB347_RS07410
uniprot id: A0A1N7EAZ6
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

588898:BB347 RS08770
gene id: 588898:BB347_RS08770
uniprot id: A0A1N7C1U3
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS05265
gene id: 588898:BB347_RS05265
uniprot id: A0A1N7DN11
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

588898:BB347 RS01255
gene id: 588898:BB347_RS01255
uniprot id: A0A1N6ZI00
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS09310
gene id: 588898:BB347_RS09310
uniprot id: A0A1N7C9F9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

588898:BB347 RS01645
gene id: 588898:BB347_RS01645
uniprot id: A0A1N6Z9F6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

588898:BB347 RS00330
gene id: 588898:BB347_RS00330
uniprot id: A0A1N7A221
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

588898:BB347 RS12765
gene id: 588898:BB347_RS12765
uniprot id: A0A1N7FTD2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

588898:BB347 RS08440
gene id: 588898:BB347_RS08440
uniprot id: A0A1N7BXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

588898:BB347 RS03630
gene id: 588898:BB347_RS03630
uniprot id: A0A1N6Y567
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

588898:BB347 RS01575
gene id: 588898:BB347_RS01575
uniprot id: A0A1P8RHG6
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

588898:BB347 RS12165
gene id: 588898:BB347_RS12165
uniprot id: A0A1N7FPI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

588898:BB347 RS09100
gene id: 588898:BB347_RS09100
uniprot id: A0A1N7C6L0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

588898:BB347 RS11155
gene id: 588898:BB347_RS11155
uniprot id: A0A1P8RHV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

588898:BB347 RS10600
gene id: 588898:BB347_RS10600
uniprot id: A0A1N7CRP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS10075
gene id: 588898:BB347_RS10075
uniprot id: A0A1N7CJX3
names: Similarity
messages: Belongs to the citrate synthase family.

588898:BB347 RS06210
gene id: 588898:BB347_RS06210
uniprot id: A0A1N7DYH4
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS11290
gene id: 588898:BB347_RS11290
uniprot id: A0A1N7D164
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

588898:BB347 RS03125
gene id: 588898:BB347_RS03125
uniprot id: A0A1N6YF14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

588898:BB347 RS12275
gene id: 588898:BB347_RS12275
uniprot id: A0A1N7FQ51
names: Similarity
messages: Belongs to the AOR/FOR family.

588898:BB347 RS13195
gene id: 588898:BB347_RS13195
uniprot id: A0A1N7F268
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

588898:BB347 RS11330
gene id: 588898:BB347_RS11330
uniprot id: A0A1N7D1L9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

588898:BB347 RS00190
gene id: 588898:BB347_RS00190
uniprot id: A0A1N7A502
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS12700
gene id: 588898:BB347_RS12700
uniprot id: A0A1N7FT88
names: Similarity
messages: Belongs to the UPF0201 family.

588898:BB347 RS09555
gene id: 588898:BB347_RS09555
uniprot id: A0A1N7CD03
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

588898:BB347 RS01365
gene id: 588898:BB347_RS01365
uniprot id: A0A1N6ZFS8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

588898:BB347 RS08690
gene id: 588898:BB347_RS08690
uniprot id: A0A1N7C0N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

588898:BB347 RS09935
gene id: 588898:BB347_RS09935
uniprot id: A0A1N7CHZ5
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS06605
gene id: 588898:BB347_RS06605
uniprot id: A0A1P8RCM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

588898:BB347 RS11130
gene id: 588898:BB347_RS11130
uniprot id: A0A1P8REQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

588898:BB347 RS06985
gene id: 588898:BB347_RS06985
uniprot id: A0A1N7E5U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Belongs to the inositol monophosphatase superfamily.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS11685
gene id: 588898:BB347_RS11685
uniprot id: A0A1N7D5E0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

588898:BB347 RS00830
gene id: 588898:BB347_RS00830
uniprot id: A0A1N6ZS63
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

588898:BB347 RS05580
gene id: 588898:BB347_RS05580
uniprot id: A0A1P8RBS3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

588898:BB347 RS09965
gene id: 588898:BB347_RS09965
uniprot id: A0A1N7CIE0
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

588898:BB347 RS05500
gene id: 588898:BB347_RS05500
uniprot id: A0A1N7DQU6
names: Function
messages: Part of a potassium transport system.

588898:BB347 RS06550
gene id: 588898:BB347_RS06550
uniprot id: A0A1N7E1H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

588898:BB347 RS18600
gene id: 588898:BB347_RS18600
uniprot id: A0A1N7G5G2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

588898:BB347 RS12810
gene id: 588898:BB347_RS12810
uniprot id: A0A1N7FTN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

588898:BB347 RS14045
gene id: 588898:BB347_RS14045
uniprot id: A0A1N7FA07
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

588898:BB347 RS08520
gene id: 588898:BB347_RS08520
uniprot id: A0A1N7BYI8
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS16665
gene id: 588898:BB347_RS16665
uniprot id: A0A1N7FK66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

588898:BB347 RS13900
gene id: 588898:BB347_RS13900
uniprot id: A0A1N7F8V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS03335
gene id: 588898:BB347_RS03335
uniprot id: A0A1N6YAP9
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

588898:BB347 RS11100
gene id: 588898:BB347_RS11100
uniprot id: A0A1N7CZ71
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

588898:BB347 RS13360
gene id: 588898:BB347_RS13360
uniprot id: A0A1N7F3T6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS12415
gene id: 588898:BB347_RS12415
uniprot id: A0A1N7FRC3
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS07570
gene id: 588898:BB347_RS07570
uniprot id: A0A1N7ECB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

588898:BB347 RS00495
gene id: 588898:BB347_RS00495
uniprot id: A0A1N6ZYU2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS16230
gene id: 588898:BB347_RS16230
uniprot id: A0A1N7ACI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH.
messages: Homotetramer.

588898:BB347 RS11570
gene id: 588898:BB347_RS11570
uniprot id: A0A1N7D475
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

588898:BB347 RS02745
gene id: 588898:BB347_RS02745
uniprot id: A0A1N6YMJ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS14830
gene id: 588898:BB347_RS14830
uniprot id: A0A1N7EQK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

588898:BB347 RS14320
gene id: 588898:BB347_RS14320
uniprot id: A0A1N7EVD6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

588898:BB347 RS07540
gene id: 588898:BB347_RS07540
uniprot id: A0A1N7EC25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

588898:BB347 RS13945
gene id: 588898:BB347_RS13945
uniprot id: A0A1N7F911
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS14250
gene id: 588898:BB347_RS14250
uniprot id: A0A1N7EW16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

588898:BB347 RS12180
gene id: 588898:BB347_RS12180
uniprot id: A0A1N7FPK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

588898:BB347 RS11545
gene id: 588898:BB347_RS11545
uniprot id: A0A1N7D3W6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS12185
gene id: 588898:BB347_RS12185
uniprot id: A0A1N7FPL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

588898:BB347 RS11435
gene id: 588898:BB347_RS11435
uniprot id: A0A1N7D306
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS02795
gene id: 588898:BB347_RS02795
uniprot id: A0A1N6YLX8
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS09475
gene id: 588898:BB347_RS09475
uniprot id: A0A1N7CCD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

588898:BB347 RS09635
gene id: 588898:BB347_RS09635
uniprot id: A0A1N7CDW4
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

588898:BB347 RS14805
gene id: 588898:BB347_RS14805
uniprot id: A0A1N7EQL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

588898:BB347 RS13975
gene id: 588898:BB347_RS13975
uniprot id: A0A1N7F9C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS10245
gene id: 588898:BB347_RS10245
uniprot id: A0A1N7CMF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

588898:BB347 RS14085
gene id: 588898:BB347_RS14085
uniprot id: A0A1N7FAL0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

588898:BB347 RS01040
gene id: 588898:BB347_RS01040
uniprot id: A0A1N6ZMS4
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

588898:BB347 RS07830
gene id: 588898:BB347_RS07830
uniprot id: A0A1N7BN82
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

588898:BB347 RS08790
gene id: 588898:BB347_RS08790
uniprot id: A0A1N7C260
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

588898:BB347 RS02615
gene id: 588898:BB347_RS02615
uniprot id: A0A1N6YQB3
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

588898:BB347 RS11590
gene id: 588898:BB347_RS11590
uniprot id: A0A1N7D4S0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS01055
gene id: 588898:BB347_RS01055
uniprot id: A0A1N6ZMG8
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS11520
gene id: 588898:BB347_RS11520
uniprot id: A0A1N7D480
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS10360
gene id: 588898:BB347_RS10360
uniprot id: A0A1N7CNX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

588898:BB347 RS04075
gene id: 588898:BB347_RS04075
uniprot id: A0A1N6XUD5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

588898:BB347 RS04310
gene id: 588898:BB347_RS04310
uniprot id: A0A1N6XP97
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

588898:BB347 RS12730
gene id: 588898:BB347_RS12730
uniprot id: A0A1N7FTG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

588898:BB347 RS05320
gene id: 588898:BB347_RS05320
uniprot id: A0A1N7DNM8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

588898:BB347 RS00810
gene id: 588898:BB347_RS00810
uniprot id: A0A1N6ZST1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

588898:BB347 RS12925
gene id: 588898:BB347_RS12925
uniprot id: A0A1N7FUG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Homodimer.

588898:BB347 RS14740
gene id: 588898:BB347_RS14740
uniprot id: A0A1N7ER99
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

588898:BB347 RS15430
gene id: 588898:BB347_RS15430
uniprot id: A0A1N7EKT4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

588898:BB347 RS01290
gene id: 588898:BB347_RS01290
uniprot id: A0A1N6ZH80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

588898:BB347 RS10410
gene id: 588898:BB347_RS10410
uniprot id: A0A1N7CPN5
names: Similarity
messages: Belongs to the UPF0175 family.

588898:BB347 RS08395
gene id: 588898:BB347_RS08395
uniprot id: A0A1N7BX75
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

588898:BB347 RS18230
gene id: 588898:BB347_RS18230
uniprot id: A0A1N7G1M9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

588898:BB347 RS01190
gene id: 588898:BB347_RS01190
uniprot id: A0A1N6ZJF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

588898:BB347 RS08640
gene id: 588898:BB347_RS08640
uniprot id: A0A1N7C019
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS15970
gene id: 588898:BB347_RS15970
uniprot id: A0A1N7AH12
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS15040
gene id: 588898:BB347_RS15040
uniprot id: A0A1N7EP54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

588898:BB347 RS05525
gene id: 588898:BB347_RS05525
uniprot id: A0A1N7DR98
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS15995
gene id: 588898:BB347_RS15995
uniprot id: A0A1N7AGT3
names: Similarity
messages: Belongs to the alkaline phosphatase family.

588898:BB347 RS17340
gene id: 588898:BB347_RS17340
uniprot id: A0A1N7FI63
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS02045
gene id: 588898:BB347_RS02045
uniprot id: A0A1N6Z1U3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

588898:BB347 RS02120
gene id: 588898:BB347_RS02120
uniprot id: A0A1N6Z0B5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

588898:BB347 RS06590
gene id: 588898:BB347_RS06590
uniprot id: A0A1N7E245
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

588898:BB347 RS06865
gene id: 588898:BB347_RS06865
uniprot id: A0A1N7E506
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

588898:BB347 RS05420
gene id: 588898:BB347_RS05420
uniprot id: A0A1N7DPS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

588898:BB347 RS16530
gene id: 588898:BB347_RS16530
uniprot id: A0A1P8RIM6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

588898:BB347 RS11110
gene id: 588898:BB347_RS11110
uniprot id: A0A1N7CZ50
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

588898:BB347 RS07100
gene id: 588898:BB347_RS07100
uniprot id: A0A1N7E7H9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS09135
gene id: 588898:BB347_RS09135
uniprot id: A0A1N7C6V0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

588898:BB347 RS01195
gene id: 588898:BB347_RS01195
uniprot id: A0A1N6ZJ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

588898:BB347 RS16805
gene id: 588898:BB347_RS16805
uniprot id: A0A1N7FLI0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

588898:BB347 RS06615
gene id: 588898:BB347_RS06615
uniprot id: A0A1N7E2C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

588898:BB347 RS04305
gene id: 588898:BB347_RS04305
uniprot id: A0A1P8RHS7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

588898:BB347 RS01230
gene id: 588898:BB347_RS01230
uniprot id: A0A1N6ZIA9
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

588898:BB347 RS08970
gene id: 588898:BB347_RS08970
uniprot id: A0A1N7C4Z4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

588898:BB347 RS08270
gene id: 588898:BB347_RS08270
uniprot id: A0A1N7BVD2
names: Function
messages: Part of a potassium transport system.

588898:BB347 RS02020
gene id: 588898:BB347_RS02020
uniprot id: A0A1N6Z221
names: Similarity
messages: Belongs to the peptidase M24B family.

588898:BB347 RS03010
gene id: 588898:BB347_RS03010
uniprot id: A0A1N6YHI3
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

588898:BB347 RS01000
gene id: 588898:BB347_RS01000
uniprot id: A0A1N6ZNX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

588898:BB347 RS14220
gene id: 588898:BB347_RS14220
uniprot id: A0A1N7EW89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS17115
gene id: 588898:BB347_RS17115
uniprot id: A0A1N7FGR1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

588898:BB347 RS03580
gene id: 588898:BB347_RS03580
uniprot id: A0A1N6Y5Q4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS01885
gene id: 588898:BB347_RS01885
uniprot id: A0A1N6Z4N4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

588898:BB347 RS13235
gene id: 588898:BB347_RS13235
uniprot id: A0A1N7F2P8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

588898:BB347 RS15725
gene id: 588898:BB347_RS15725
uniprot id: A0A1N7ALD9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

588898:BB347 RS12805
gene id: 588898:BB347_RS12805
uniprot id: A0A1N7FTQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

588898:BB347 RS11630
gene id: 588898:BB347_RS11630
uniprot id: A0A1N7D5E9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

588898:BB347 RS06560
gene id: 588898:BB347_RS06560
uniprot id: A0A1N7E1S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

588898:BB347 RS13750
gene id: 588898:BB347_RS13750
uniprot id: A0A1N7F7E0
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS04345
gene id: 588898:BB347_RS04345
uniprot id: A0A1N6XNE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS06515
gene id: 588898:BB347_RS06515
uniprot id: A0A1N7E1C2
names: Similarity
messages: Belongs to the UPF0045 family.

588898:BB347 RS10645
gene id: 588898:BB347_RS10645
uniprot id: A0A1N7CSN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

588898:BB347 RS14905
gene id: 588898:BB347_RS14905
uniprot id: A0A1N7EQ24
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

588898:BB347 RS13205
gene id: 588898:BB347_RS13205
uniprot id: A0A1N7F253
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

588898:BB347 RS03760
gene id: 588898:BB347_RS03760
uniprot id: A0A1N6Y1T6
names: Similarity
messages: Belongs to the CutA family.

588898:BB347 RS12860
gene id: 588898:BB347_RS12860
uniprot id: A0A1N7FTY9
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS08950
gene id: 588898:BB347_RS08950
uniprot id: A0A1N7C4S4
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS10590
gene id: 588898:BB347_RS10590
uniprot id: A0A1N7CS12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

588898:BB347 RS17355
gene id: 588898:BB347_RS17355
uniprot id: A0A1N7FIL3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS15200
gene id: 588898:BB347_RS15200
uniprot id: A0A1N7EMQ5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

588898:BB347 RS00105
gene id: 588898:BB347_RS00105
uniprot id: A0A1N7A6K5
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS12880
gene id: 588898:BB347_RS12880
uniprot id: A0A1N7FUF0
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS15450
gene id: 588898:BB347_RS15450
uniprot id: A0A1N7EKE4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

588898:BB347 RS04830
gene id: 588898:BB347_RS04830
uniprot id: A0A1N6XBG7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS12845
gene id: 588898:BB347_RS12845
uniprot id: A0A1N7FUA4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

588898:BB347 RS03020
gene id: 588898:BB347_RS03020
uniprot id: A0A1N6YH09
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS07580
gene id: 588898:BB347_RS07580
uniprot id: A0A1N7EC75
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

588898:BB347 RS06855
gene id: 588898:BB347_RS06855
uniprot id: A0A1P8RHL9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

588898:BB347 RS13175
gene id: 588898:BB347_RS13175
uniprot id: A0A1N7F1T1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS04465
gene id: 588898:BB347_RS04465
uniprot id: A0A1N6XKL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

588898:BB347 RS04020
gene id: 588898:BB347_RS04020
uniprot id: A0A1N6XVH1
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

588898:BB347 RS07080
gene id: 588898:BB347_RS07080
uniprot id: A0A1N7E773
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS04840
gene id: 588898:BB347_RS04840
uniprot id: A0A1P8RBF3
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS07555
gene id: 588898:BB347_RS07555
uniprot id: A0A1N7EC88
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

588898:BB347 RS00505
gene id: 588898:BB347_RS00505
uniprot id: A0A1N6ZYG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS08990
gene id: 588898:BB347_RS08990
uniprot id: A0A1N7C514
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

588898:BB347 RS05025
gene id: 588898:BB347_RS05025
uniprot id: A0A1N6X6H9
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

588898:BB347 RS07585
gene id: 588898:BB347_RS07585
uniprot id: A0A1N7EC80
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

588898:BB347 RS06415
gene id: 588898:BB347_RS06415
uniprot id: A0A1N7E0V4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

588898:BB347 RS03225
gene id: 588898:BB347_RS03225
uniprot id: A0A1N6YCX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

588898:BB347 RS01175
gene id: 588898:BB347_RS01175
uniprot id: A0A1N6ZJQ4
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

588898:BB347 RS01210
gene id: 588898:BB347_RS01210
uniprot id: A0A1P8RHR7
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

588898:BB347 RS11255
gene id: 588898:BB347_RS11255
uniprot id: A0A1N7D0T7
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

588898:BB347 RS10605
gene id: 588898:BB347_RS10605
uniprot id: A0A1N7CS33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

588898:BB347 RS10910
gene id: 588898:BB347_RS10910
uniprot id: A0A1N7CW58
names: Similarity
messages: Belongs to the PspA/IM30 family.

588898:BB347 RS04030
gene id: 588898:BB347_RS04030
uniprot id: A0A1P8RHJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylamine corrinoid protein family.
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

588898:BB347 RS13375
gene id: 588898:BB347_RS13375
uniprot id: A0A1N7F3W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

588898:BB347 RS05680
gene id: 588898:BB347_RS05680
uniprot id: A0A1N7DSR6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

588898:BB347 RS03825
gene id: 588898:BB347_RS03825
uniprot id: A0A1N6Y0H1
names: Similarity
messages: Belongs to the BtpA family.

588898:BB347 RS12470
gene id: 588898:BB347_RS12470
uniprot id: A0A1P8RHV6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS12585
gene id: 588898:BB347_RS12585
uniprot id: A0A1P8RFD8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

588898:BB347 RS01310
gene id: 588898:BB347_RS01310
uniprot id: A0A1N6ZGQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS05250
gene id: 588898:BB347_RS05250
uniprot id: A0A1N7DMV8
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

588898:BB347 RS15580
gene id: 588898:BB347_RS15580
uniprot id: A0A1N7APE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

588898:BB347 RS11010
gene id: 588898:BB347_RS11010
uniprot id: A0A1N7CXY2
names: Similarity
messages: Belongs to the Ahb/Nir family.

588898:BB347 RS01200
gene id: 588898:BB347_RS01200
uniprot id: A0A1N6ZJ85
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

588898:BB347 RS05435
gene id: 588898:BB347_RS05435
uniprot id: A0A1P8RHL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

588898:BB347 RS11210
gene id: 588898:BB347_RS11210
uniprot id: A0A1N7D0R2
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

588898:BB347 RS17220
gene id: 588898:BB347_RS17220
uniprot id: A0A1N7FGZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

588898:BB347 RS16390
gene id: 588898:BB347_RS16390
uniprot id: A0A1N7A9F9
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

588898:BB347 RS00460
gene id: 588898:BB347_RS00460
uniprot id: A0A1N6ZZA8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

588898:BB347 RS13810
gene id: 588898:BB347_RS13810
uniprot id: A0A1N7F7Y9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

588898:BB347 RS09215
gene id: 588898:BB347_RS09215
uniprot id: A0A1N7C7U7
names: Similarity
messages: Belongs to the UPF0045 family.

588898:BB347 RS12330
gene id: 588898:BB347_RS12330
uniprot id: A0A1N7FQR8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.

588898:BB347 RS05635
gene id: 588898:BB347_RS05635
uniprot id: A0A1N7DS48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

588898:BB347 RS01500
gene id: 588898:BB347_RS01500
uniprot id: A0A1N6ZCD8
names: Similarity
messages: Belongs to the peptidase M20A family.

588898:BB347 RS05065
gene id: 588898:BB347_RS05065
uniprot id: A0A1N6X5K9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS08540
gene id: 588898:BB347_RS08540
uniprot id: A0A1N7BYP7
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS10660
gene id: 588898:BB347_RS10660
uniprot id: A0A1N7CSV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

588898:BB347 RS04750
gene id: 588898:BB347_RS04750
uniprot id: A0A1N6XDF9
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS18105
gene id: 588898:BB347_RS18105
uniprot id: A0A1N7G0M3
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

588898:BB347 RS07865
gene id: 588898:BB347_RS07865
uniprot id: A0A1N7BP01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

588898:BB347 RS09485
gene id: 588898:BB347_RS09485
uniprot id: A0A1N7CBY5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS06110
gene id: 588898:BB347_RS06110
uniprot id: A0A1N7DX78
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS12485
gene id: 588898:BB347_RS12485
uniprot id: A0A1N7FRJ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS16740
gene id: 588898:BB347_RS16740
uniprot id: A0A1N7FKV0
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS10690
gene id: 588898:BB347_RS10690
uniprot id: A0A1N7CT76
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS07205
gene id: 588898:BB347_RS07205
uniprot id: A0A1N7E8H3
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

588898:BB347 RS15275
gene id: 588898:BB347_RS15275
uniprot id: A0A1N7ELT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

588898:BB347 RS14070
gene id: 588898:BB347_RS14070
uniprot id: A0A1N7FAB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

588898:BB347 RS06255
gene id: 588898:BB347_RS06255
uniprot id: A0A1N7DYV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

588898:BB347 RS11410
gene id: 588898:BB347_RS11410
uniprot id: A0A1N7D2J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS16335
gene id: 588898:BB347_RS16335
uniprot id: A0A1N7AAL6
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS01235
gene id: 588898:BB347_RS01235
uniprot id: A0A1N6ZI02
names: Similarity
messages: Belongs to the eIF-2-alpha family.

588898:BB347 RS07645
gene id: 588898:BB347_RS07645
uniprot id: A0A1N7ED20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

588898:BB347 RS16360
gene id: 588898:BB347_RS16360
uniprot id: A0A1N7AA59
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

588898:BB347 RS09095
gene id: 588898:BB347_RS09095
uniprot id: A0A1N7C686
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

588898:BB347 RS13715
gene id: 588898:BB347_RS13715
uniprot id: A0A1N7F6Z2
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS03750
gene id: 588898:BB347_RS03750
uniprot id: A0A1N6Y1Q9
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

588898:BB347 RS00980
gene id: 588898:BB347_RS00980
uniprot id: A0A1N6ZPH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS05830
gene id: 588898:BB347_RS05830
uniprot id: A0A1N7DUF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

588898:BB347 RS09440
gene id: 588898:BB347_RS09440
uniprot id: A0A1N7CBA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

588898:BB347 RS12610
gene id: 588898:BB347_RS12610
uniprot id: A0A1N7FS92
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

588898:BB347 RS07660
gene id: 588898:BB347_RS07660
uniprot id: A0A1N7ED61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

588898:BB347 RS12250
gene id: 588898:BB347_RS12250
uniprot id: A0A1N7FQ18
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS05035
gene id: 588898:BB347_RS05035
uniprot id: A0A1N6X677
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

588898:BB347 RS11455
gene id: 588898:BB347_RS11455
uniprot id: A0A1N7D3C8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS09140
gene id: 588898:BB347_RS09140
uniprot id: A0A1N7C7E3
names: Similarity
messages: Belongs to the thioesterase PaaI family.

588898:BB347 RS05480
gene id: 588898:BB347_RS05480
uniprot id: A0A1N7DQL5
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.

588898:BB347 RS16790
gene id: 588898:BB347_RS16790
uniprot id: A0A1N7FLF2
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

588898:BB347 RS07650
gene id: 588898:BB347_RS07650
uniprot id: A0A1N7ECW8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

588898:BB347 RS08700
gene id: 588898:BB347_RS08700
uniprot id: A0A1N7C0X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

588898:BB347 RS14015
gene id: 588898:BB347_RS14015
uniprot id: A0A1N7FA38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

588898:BB347 RS09950
gene id: 588898:BB347_RS09950
uniprot id: A0A1N7CI47
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

588898:BB347 RS01535
gene id: 588898:BB347_RS01535
uniprot id: A0A1N6ZBM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

588898:BB347 RS06275
gene id: 588898:BB347_RS06275
uniprot id: A0A1N7DZ34
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS12930
gene id: 588898:BB347_RS12930
uniprot id: A0A1P8RHX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.

588898:BB347 RS16760
gene id: 588898:BB347_RS16760
uniprot id: A0A1N7FKW1
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS01510
gene id: 588898:BB347_RS01510
uniprot id: A0A1N6ZC13
names: Similarity
messages: Belongs to the peptidase M20A family.

588898:BB347 RS13065
gene id: 588898:BB347_RS13065
uniprot id: A0A1N7F0S3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

588898:BB347 RS09895
gene id: 588898:BB347_RS09895
uniprot id: A0A1N7CHA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

588898:BB347 RS06100
gene id: 588898:BB347_RS06100
uniprot id: A0A1N7DX45
names: Similarity
messages: Belongs to the catalase family.

588898:BB347 RS12150
gene id: 588898:BB347_RS12150
uniprot id: A0A1N7FPI1
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Part of the RNA polymerase complex.

588898:BB347 RS07710
gene id: 588898:BB347_RS07710
uniprot id: A0A1N7EDL3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

588898:BB347 RS11905
gene id: 588898:BB347_RS11905
uniprot id: A0A1N7G7W0
names: Similarity
messages: Belongs to the SUI1 family.

588898:BB347 RS09795
gene id: 588898:BB347_RS09795
uniprot id: A0A1N7CG68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

588898:BB347 RS11225
gene id: 588898:BB347_RS11225
uniprot id: A0A1N7D0J1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

588898:BB347 RS10130
gene id: 588898:BB347_RS10130
uniprot id: A0A1N7CL83
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

588898:BB347 RS02215
gene id: 588898:BB347_RS02215
uniprot id: A0A1N6YYE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

588898:BB347 RS07290
gene id: 588898:BB347_RS07290
uniprot id: A0A1N7E9H5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

588898:BB347 RS01110
gene id: 588898:BB347_RS01110
uniprot id: A0A1N6ZKX8
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

588898:BB347 RS05770
gene id: 588898:BB347_RS05770
uniprot id: A0A1N7DTK3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

588898:BB347 RS06240
gene id: 588898:BB347_RS06240
uniprot id: A0A1N7DYX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS08720
gene id: 588898:BB347_RS08720
uniprot id: A0A1N7C1A5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

588898:BB347 RS12205
gene id: 588898:BB347_RS12205
uniprot id: A0A1N7FPT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

588898:BB347 RS04050
gene id: 588898:BB347_RS04050
uniprot id: A0A1N6XUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS00240
gene id: 588898:BB347_RS00240
uniprot id: A0A1N7A3Y5
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

588898:BB347 RS07915
gene id: 588898:BB347_RS07915
uniprot id: A0A1N7BPZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

588898:BB347 RS03975
gene id: 588898:BB347_RS03975
uniprot id: A0A1N6XX14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

588898:BB347 RS03235
gene id: 588898:BB347_RS03235
uniprot id: A0A1N6YCS8
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS12865
gene id: 588898:BB347_RS12865
uniprot id: A0A1N7FUA2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS05510
gene id: 588898:BB347_RS05510
uniprot id: A0A1N7DR39
names: Function
messages: Part of a potassium transport system.

588898:BB347 RS06235
gene id: 588898:BB347_RS06235
uniprot id: A0A1N7DYP3
names: Similarity
messages: Belongs to the TrpF family.

588898:BB347 RS15630
gene id: 588898:BB347_RS15630
uniprot id: A0A1N7ANJ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

588898:BB347 RS10620
gene id: 588898:BB347_RS10620
uniprot id: A0A1N7CS97
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

588898:BB347 RS03620
gene id: 588898:BB347_RS03620
uniprot id: A0A1N6Y560
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

588898:BB347 RS09305
gene id: 588898:BB347_RS09305
uniprot id: A0A1N7C996
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

588898:BB347 RS00680
gene id: 588898:BB347_RS00680
uniprot id: A0A1N6ZUW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

588898:BB347 RS12430
gene id: 588898:BB347_RS12430
uniprot id: A0A1N7FR43
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS07250
gene id: 588898:BB347_RS07250
uniprot id: A0A1N7E8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Cytoplasm
messages: Gas vesicle
messages: Vesicle

588898:BB347 RS13425
gene id: 588898:BB347_RS13425
uniprot id: A0A1N7F4T6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

588898:BB347 RS11420
gene id: 588898:BB347_RS11420
uniprot id: A0A1N7D2L3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS09730
gene id: 588898:BB347_RS09730
uniprot id: A0A1P8RDZ0
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

588898:BB347 RS14265
gene id: 588898:BB347_RS14265
uniprot id: A0A1N7EVU3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

588898:BB347 RS00315
gene id: 588898:BB347_RS00315
uniprot id: A0A1N7A274
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

588898:BB347 RS02770
gene id: 588898:BB347_RS02770
uniprot id: A0A1N6YM67
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

588898:BB347 RS08645
gene id: 588898:BB347_RS08645
uniprot id: A0A1P8RDM0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

588898:BB347 RS15195
gene id: 588898:BB347_RS15195
uniprot id: A0A1P8RI15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P(II) protein family.
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

588898:BB347 RS02260
gene id: 588898:BB347_RS02260
uniprot id: A0A1P8RA13
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS08075
gene id: 588898:BB347_RS08075
uniprot id: A0A1N7BS21
names: Subcellular Location Annotation
messages: Cytoplasm

588898:BB347 RS06650
gene id: 588898:BB347_RS06650
uniprot id: A0A1N7E2P5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

588898:BB347 RS07855
gene id: 588898:BB347_RS07855
uniprot id: A0A1N7BNR2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS12025
gene id: 588898:BB347_RS12025
uniprot id: A0A1N7G8P7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

588898:BB347 RS13850
gene id: 588898:BB347_RS13850
uniprot id: A0A1N7F899
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

588898:BB347 RS02525
gene id: 588898:BB347_RS02525
uniprot id: A0A1N6YSC4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS06670
gene id: 588898:BB347_RS06670
uniprot id: A0A1N7E343
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

588898:BB347 RS09240
gene id: 588898:BB347_RS09240
uniprot id: A0A1N7C8U5
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

588898:BB347 RS00350
gene id: 588898:BB347_RS00350
uniprot id: A0A1N7A1C6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS12405
gene id: 588898:BB347_RS12405
uniprot id: A0A1N7FQZ7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

588898:BB347 RS12145
gene id: 588898:BB347_RS12145
uniprot id: A0A1N7FPL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

588898:BB347 RS04240
gene id: 588898:BB347_RS04240
uniprot id: A0A1N6XQD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

588898:BB347 RS03005
gene id: 588898:BB347_RS03005
uniprot id: A0A1N6YHN4
names: Similarity
messages: Belongs to the complex I subunit 3 family.

588898:BB347 RS12325
gene id: 588898:BB347_RS12325
uniprot id: A0A1N7FQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

588898:BB347 RS05540
gene id: 588898:BB347_RS05540
uniprot id: A0A1N7DRF0
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS10785
gene id: 588898:BB347_RS10785
uniprot id: A0A1N7CUR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

588898:BB347 RS06695
gene id: 588898:BB347_RS06695
uniprot id: A0A1N7E306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

588898:BB347 RS09655
gene id: 588898:BB347_RS09655
uniprot id: A0A1N7CE79
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS03680
gene id: 588898:BB347_RS03680
uniprot id: A0A1N6Y3P3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

588898:BB347 RS00165
gene id: 588898:BB347_RS00165
uniprot id: A0A1N7A5F4
names: Subcellular Location Annotation
messages: Cytoplasm

588898:BB347 RS15325
gene id: 588898:BB347_RS15325
uniprot id: A0A1N7ELI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

588898:BB347 RS10810
gene id: 588898:BB347_RS10810
uniprot id: A0A1P8REH7
names: Function
messages: Part of a potassium transport system.

588898:BB347 RS12615
gene id: 588898:BB347_RS12615
uniprot id: A0A1N7FSC6
names: Similarity
messages: Belongs to the threonine aldolase family.

588898:BB347 RS16420
gene id: 588898:BB347_RS16420
uniprot id: A0A1N7A926
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

588898:BB347 RS06440
gene id: 588898:BB347_RS06440
uniprot id: A0A1N7E118
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS01060
gene id: 588898:BB347_RS01060
uniprot id: A0A1N6ZM95
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS01990
gene id: 588898:BB347_RS01990
uniprot id: A0A1N6Z2Q4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

588898:BB347 RS12295
gene id: 588898:BB347_RS12295
uniprot id: A0A1N7FQH2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

588898:BB347 RS15060
gene id: 588898:BB347_RS15060
uniprot id: A0A1N7EPD2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

588898:BB347 RS03665
gene id: 588898:BB347_RS03665
uniprot id: A0A1N6Y481
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

588898:BB347 RS13465
gene id: 588898:BB347_RS13465
uniprot id: A0A1N7F4S9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

588898:BB347 RS15820
gene id: 588898:BB347_RS15820
uniprot id: A0A1N7AJN9
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS12545
gene id: 588898:BB347_RS12545
uniprot id: A0A1N7FRR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS10505
gene id: 588898:BB347_RS10505
uniprot id: A0A1N7CQL0
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS10720
gene id: 588898:BB347_RS10720
uniprot id: A0A1P8RHT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS07895
gene id: 588898:BB347_RS07895
uniprot id: A0A1N7BPD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

588898:BB347 RS00120
gene id: 588898:BB347_RS00120
uniprot id: A0A1N7A6E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

588898:BB347 RS08590
gene id: 588898:BB347_RS08590
uniprot id: A0A1N7BZH1
names: Similarity
messages: Belongs to the peptidase S1C family.

588898:BB347 RS02635
gene id: 588898:BB347_RS02635
uniprot id: A0A1N6YPW0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS06815
gene id: 588898:BB347_RS06815
uniprot id: A0A1N7E4C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

588898:BB347 RS09125
gene id: 588898:BB347_RS09125
uniprot id: A0A1N7C6R8
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

588898:BB347 RS09180
gene id: 588898:BB347_RS09180
uniprot id: A0A1N7C804
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

588898:BB347 RS13480
gene id: 588898:BB347_RS13480
uniprot id: A0A1N7F532
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

588898:BB347 RS10835
gene id: 588898:BB347_RS10835
uniprot id: A0A1N7CV71
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

588898:BB347 RS01030
gene id: 588898:BB347_RS01030
uniprot id: A0A1N6ZMX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

588898:BB347 RS04860
gene id: 588898:BB347_RS04860
uniprot id: A0A1N6XAD4
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

588898:BB347 RS12515
gene id: 588898:BB347_RS12515
uniprot id: A0A1N7FRN7
names: Similarity
messages: Belongs to the TFIIB family.

588898:BB347 RS04395
gene id: 588898:BB347_RS04395
uniprot id: A0A1N6XLX1
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

588898:BB347 RS01105
gene id: 588898:BB347_RS01105
uniprot id: A0A1N6ZL64
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

588898:BB347 RS10725
gene id: 588898:BB347_RS10725
uniprot id: A0A1N7CU94
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

588898:BB347 RS04585
gene id: 588898:BB347_RS04585
uniprot id: A0A1N6XHA6
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS04080
gene id: 588898:BB347_RS04080
uniprot id: A0A1N6XU38
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

588898:BB347 RS00420
gene id: 588898:BB347_RS00420
uniprot id: A0A1N7A087
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

588898:BB347 RS11970
gene id: 588898:BB347_RS11970
uniprot id: A0A1N7G8B3
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

588898:BB347 RS04505
gene id: 588898:BB347_RS04505
uniprot id: A0A1P8RBE2
names: Similarity
messages: Belongs to the FUN14 family.

588898:BB347 RS00995
gene id: 588898:BB347_RS00995
uniprot id: A0A1N6ZNZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

588898:BB347 RS16815
gene id: 588898:BB347_RS16815
uniprot id: A0A1N7FLD1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS08575
gene id: 588898:BB347_RS08575
uniprot id: A0A1N7BZ94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

588898:BB347 RS10010
gene id: 588898:BB347_RS10010
uniprot id: A0A1N7CJ34
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS12225
gene id: 588898:BB347_RS12225
uniprot id: A0A1N7FQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

588898:BB347 RS12230
gene id: 588898:BB347_RS12230
uniprot id: A0A1N7FQ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

588898:BB347 RS08945
gene id: 588898:BB347_RS08945
uniprot id: A0A1N7C4Q7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

588898:BB347 RS07240
gene id: 588898:BB347_RS07240
uniprot id: A0A1N7E8W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

588898:BB347 RS13150
gene id: 588898:BB347_RS13150
uniprot id: A0A1N7F213
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS04970
gene id: 588898:BB347_RS04970
uniprot id: A0A1N6X7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

588898:BB347 RS07365
gene id: 588898:BB347_RS07365
uniprot id: A0A1N7EA79
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

588898:BB347 RS08065
gene id: 588898:BB347_RS08065
uniprot id: A0A1N7BRV3
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

588898:BB347 RS07530
gene id: 588898:BB347_RS07530
uniprot id: A0A1N7EBU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

588898:BB347 RS15940
gene id: 588898:BB347_RS15940
uniprot id: A0A1N7AHT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

588898:BB347 RS13955
gene id: 588898:BB347_RS13955
uniprot id: A0A1N7F915
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS17175
gene id: 588898:BB347_RS17175
uniprot id: A0A1N7FGL2
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

588898:BB347 RS00425
gene id: 588898:BB347_RS00425
uniprot id: A0A1N7A089
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

588898:BB347 RS04605
gene id: 588898:BB347_RS04605
uniprot id: A0A1N6XGS7
names: Similarity
messages: Belongs to the UPF0047 family.

588898:BB347 RS13285
gene id: 588898:BB347_RS13285
uniprot id: A0A1N7F374
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

588898:BB347 RS06665
gene id: 588898:BB347_RS06665
uniprot id: A0A1N7E2R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

588898:BB347 RS15835
gene id: 588898:BB347_RS15835
uniprot id: A0A1N7AJ56
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS07560
gene id: 588898:BB347_RS07560
uniprot id: A0A1N7EC79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

588898:BB347 RS07685
gene id: 588898:BB347_RS07685
uniprot id: A0A1N7ED56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

588898:BB347 RS02385
gene id: 588898:BB347_RS02385
uniprot id: A0A1P8RAK8
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

588898:BB347 RS16895
gene id: 588898:BB347_RS16895
uniprot id: A0A1N7FM41
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS05070
gene id: 588898:BB347_RS05070
uniprot id: A0A1N6X5Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS11740
gene id: 588898:BB347_RS11740
uniprot id: A0A1N7D5Y2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

588898:BB347 RS14035
gene id: 588898:BB347_RS14035
uniprot id: A0A1N7FA36
names: Similarity
messages: Belongs to the aspartokinase family.

588898:BB347 RS00490
gene id: 588898:BB347_RS00490
uniprot id: A0A1N6ZYX6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS01125
gene id: 588898:BB347_RS01125
uniprot id: A0A1N6ZKT9
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

588898:BB347 RS03045
gene id: 588898:BB347_RS03045
uniprot id: A0A1N6YGT8
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS02455
gene id: 588898:BB347_RS02455
uniprot id: A0A1N6YTL5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

588898:BB347 RS08530
gene id: 588898:BB347_RS08530
uniprot id: A0A1N7BYR1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

588898:BB347 RS10170
gene id: 588898:BB347_RS10170
uniprot id: A0A1N7CLA1
names: Similarity
messages: Belongs to the HypE family.

588898:BB347 RS05905
gene id: 588898:BB347_RS05905
uniprot id: A0A1N7DV74
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

588898:BB347 RS01045
gene id: 588898:BB347_RS01045
uniprot id: A0A1N6ZMK7
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

588898:BB347 RS05410
gene id: 588898:BB347_RS05410
uniprot id: A0A1N7DPN7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS09665
gene id: 588898:BB347_RS09665
uniprot id: A0A1N7CES0
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

588898:BB347 RS13470
gene id: 588898:BB347_RS13470
uniprot id: A0A1N7F549
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

588898:BB347 RS06585
gene id: 588898:BB347_RS06585
uniprot id: A0A1N7E1Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

588898:BB347 RS07330
gene id: 588898:BB347_RS07330
uniprot id: A0A1N7E9M4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS01795
gene id: 588898:BB347_RS01795
uniprot id: A0A1N6Z693
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS11945
gene id: 588898:BB347_RS11945
uniprot id: A0A1N7G8L5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

588898:BB347 RS10490
gene id: 588898:BB347_RS10490
uniprot id: A0A1N7CQK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

588898:BB347 RS12760
gene id: 588898:BB347_RS12760
uniprot id: A0A1N7FTC2
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

588898:BB347 RS10500
gene id: 588898:BB347_RS10500
uniprot id: A0A1N7CR18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

588898:BB347 RS14400
gene id: 588898:BB347_RS14400
uniprot id: A0A1N7EUC0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS09720
gene id: 588898:BB347_RS09720
uniprot id: A0A1N7CF96
names: Subcellular Location Annotation
messages: Cell membrane

588898:BB347 RS03660
gene id: 588898:BB347_RS03660
uniprot id: A0A1N6Y466
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

588898:BB347 RS06140
gene id: 588898:BB347_RS06140
uniprot id: A0A1N7DXK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

588898:BB347 RS04705
gene id: 588898:BB347_RS04705
uniprot id: A0A1N6XE72
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

588898:BB347 RS14685
gene id: 588898:BB347_RS14685
uniprot id: A0A1N7ERM7
names: Similarity
messages: Belongs to the TPP enzyme family.

588898:BB347 RS13200
gene id: 588898:BB347_RS13200
uniprot id: A0A1N7F299
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

588898:BB347 RS01130
gene id: 588898:BB347_RS01130
uniprot id: A0A1N6ZKU0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

588898:BB347 RS05085
gene id: 588898:BB347_RS05085
uniprot id: A0A1N6X556
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

588898:BB347 RS16660
gene id: 588898:BB347_RS16660
uniprot id: A0A1N7FJZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

588898:BB347 RS04190
gene id: 588898:BB347_RS04190
uniprot id: A0A1N6XRN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

588898:BB347 RS17205
gene id: 588898:BB347_RS17205
uniprot id: A0A1N7FH95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

588898:BB347 RS01690
gene id: 588898:BB347_RS01690
uniprot id: A0A1N6Z8E4
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS00480
gene id: 588898:BB347_RS00480
uniprot id: A0A1N6ZYZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

588898:BB347 RS15975
gene id: 588898:BB347_RS15975
uniprot id: A0A1N7AGW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

588898:BB347 RS10210
gene id: 588898:BB347_RS10210
uniprot id: A0A1N7CLU3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

588898:BB347 RS02930
gene id: 588898:BB347_RS02930
uniprot id: A0A1N6YJ95
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

588898:BB347 RS10800
gene id: 588898:BB347_RS10800
uniprot id: A0A1N7CUZ1
names: Similarity
messages: Belongs to the thymidylate kinase family.

588898:BB347 RS06340
gene id: 588898:BB347_RS06340
uniprot id: A0A1N7DZX1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS05170
gene id: 588898:BB347_RS05170
uniprot id: A0A1N7DLX5
names: Similarity
messages: Belongs to the manganese catalase family.

588898:BB347 RS03055
gene id: 588898:BB347_RS03055
uniprot id: A0A1N6YGG5
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS15290
gene id: 588898:BB347_RS15290
uniprot id: A0A1N7ELQ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

588898:BB347 RS13860
gene id: 588898:BB347_RS13860
uniprot id: A0A1N7F895
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

588898:BB347 RS04695
gene id: 588898:BB347_RS04695
uniprot id: A0A1N6XEP9
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

588898:BB347 RS09570
gene id: 588898:BB347_RS09570
uniprot id: A0A1N7CD34
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS03145
gene id: 588898:BB347_RS03145
uniprot id: A0A1N6YEG0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS02575
gene id: 588898:BB347_RS02575
uniprot id: A0A1N6YR78
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

588898:BB347 RS05670
gene id: 588898:BB347_RS05670
uniprot id: A0A1N7DSM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

588898:BB347 RS03815
gene id: 588898:BB347_RS03815
uniprot id: A0A1N6Y0A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

588898:BB347 RS13695
gene id: 588898:BB347_RS13695
uniprot id: A0A1N7F6U5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS14500
gene id: 588898:BB347_RS14500
uniprot id: A0A1N7ETG9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS16630
gene id: 588898:BB347_RS16630
uniprot id: A0A1N7FJX6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

588898:BB347 RS12400
gene id: 588898:BB347_RS12400
uniprot id: A0A1N7FR05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

588898:BB347 RS14930
gene id: 588898:BB347_RS14930
uniprot id: A0A1N7EPR8
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS15225
gene id: 588898:BB347_RS15225
uniprot id: A0A1P8RGT4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

588898:BB347 RS16820
gene id: 588898:BB347_RS16820
uniprot id: A0A1N7FLE7
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS07115
gene id: 588898:BB347_RS07115
uniprot id: A0A1N7E7D8
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS02010
gene id: 588898:BB347_RS02010
uniprot id: A0A1N6Z293
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

588898:BB347 RS11085
gene id: 588898:BB347_RS11085
uniprot id: A0A1N7CYF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

588898:BB347 RS12840
gene id: 588898:BB347_RS12840
uniprot id: A0A1N7FU33
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

588898:BB347 RS12420
gene id: 588898:BB347_RS12420
uniprot id: A0A1N7FR76
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

588898:BB347 RS03585
gene id: 588898:BB347_RS03585
uniprot id: A0A1N6Y5X8
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS05745
gene id: 588898:BB347_RS05745
uniprot id: A0A1N7DTD3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

588898:BB347 RS08040
gene id: 588898:BB347_RS08040
uniprot id: A0A1N7BRU4
names: Similarity
messages: Belongs to the acylphosphatase family.

588898:BB347 RS09225
gene id: 588898:BB347_RS09225
uniprot id: A0A1N7C8G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS07655
gene id: 588898:BB347_RS07655
uniprot id: A0A1N7ECX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

588898:BB347 RS08895
gene id: 588898:BB347_RS08895
uniprot id: A0A1N7C3L4
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

588898:BB347 RS13025
gene id: 588898:BB347_RS13025
uniprot id: A0A1N7F0Q8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

588898:BB347 RS10460
gene id: 588898:BB347_RS10460
uniprot id: A0A1N7CQA9
names: Subcellular Location Annotation
names: Subunit
messages: Monomer.
messages: Nucleus

588898:BB347 RS13755
gene id: 588898:BB347_RS13755
uniprot id: A0A1N7F7J8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS10790
gene id: 588898:BB347_RS10790
uniprot id: A0A1N7CUU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

588898:BB347 RS07370
gene id: 588898:BB347_RS07370
uniprot id: A0A1N7EAB5
names: Similarity
messages: Belongs to the arginase family.

588898:BB347 RS14245
gene id: 588898:BB347_RS14245
uniprot id: A0A1N7EW36
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

588898:BB347 RS18330
gene id: 588898:BB347_RS18330
uniprot id: A0A1N7G229
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

588898:BB347 RS17595
gene id: 588898:BB347_RS17595
uniprot id: A0A1N7GB83
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

588898:BB347 RS00870
gene id: 588898:BB347_RS00870
uniprot id: A0A1N6ZRM4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

588898:BB347 RS16425
gene id: 588898:BB347_RS16425
uniprot id: A0A1N7A8L2
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS16980
gene id: 588898:BB347_RS16980
uniprot id: A0A1N7FFI9
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

588898:BB347 RS11990
gene id: 588898:BB347_RS11990
uniprot id: A0A1N7G8H6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

588898:BB347 RS11510
gene id: 588898:BB347_RS11510
uniprot id: A0A1N7D3R5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

588898:BB347 RS15125
gene id: 588898:BB347_RS15125
uniprot id: A0A1N7ENC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

588898:BB347 RS06445
gene id: 588898:BB347_RS06445
uniprot id: A0A1N7E0Q0
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

588898:BB347 RS15715
gene id: 588898:BB347_RS15715
uniprot id: A0A1N7AM02
names: Similarity
messages: Belongs to the UPF0146 family.

588898:BB347 RS02060
gene id: 588898:BB347_RS02060
uniprot id: A0A1N6Z1H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

588898:BB347 RS01005
gene id: 588898:BB347_RS01005
uniprot id: A0A1N6ZNS6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

588898:BB347 RS10340
gene id: 588898:BB347_RS10340
uniprot id: A0A1N7CNJ9
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS09490
gene id: 588898:BB347_RS09490
uniprot id: A0A1N7CC27
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

588898:BB347 RS07445
gene id: 588898:BB347_RS07445
uniprot id: A0A1N7EB00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

588898:BB347 RS13405
gene id: 588898:BB347_RS13405
uniprot id: A0A1N7F440
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS03175
gene id: 588898:BB347_RS03175
uniprot id: A0A1N6YDX4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

588898:BB347 RS04725
gene id: 588898:BB347_RS04725
uniprot id: A0A1N6XDQ2
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

588898:BB347 RS09765
gene id: 588898:BB347_RS09765
uniprot id: A0A1N7CFS1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

588898:BB347 RS12710
gene id: 588898:BB347_RS12710
uniprot id: A0A1N7FT07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

588898:BB347 RS06640
gene id: 588898:BB347_RS06640
uniprot id: A0A1N7E2E6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

588898:BB347 RS13215
gene id: 588898:BB347_RS13215
uniprot id: A0A1P8RFR6
names: Function
messages: Protects DNA against thermal denaturation and modulates transcription.

588898:BB347 RS03880
gene id: 588898:BB347_RS03880
uniprot id: A0A1N6XZ61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

588898:BB347 RS09070
gene id: 588898:BB347_RS09070
uniprot id: A0A1N7C6B6
names: Similarity
messages: Belongs to the HypE family.

588898:BB347 RS00945
gene id: 588898:BB347_RS00945
uniprot id: A0A1N6ZQF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

588898:BB347 RS07175
gene id: 588898:BB347_RS07175
uniprot id: A0A1N7E8H5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

588898:BB347 RS14955
gene id: 588898:BB347_RS14955
uniprot id: A0A1N7EPP5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

588898:BB347 RS11280
gene id: 588898:BB347_RS11280
uniprot id: A0A1N7D1E5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

588898:BB347 RS15815
gene id: 588898:BB347_RS15815
uniprot id: A0A1N7AJJ4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

588898:BB347 RS17350
gene id: 588898:BB347_RS17350
uniprot id: A0A1N7FIF6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS10065
gene id: 588898:BB347_RS10065
uniprot id: A0A1N7CK05
names: Similarity
messages: Belongs to the RutC family.

588898:BB347 RS01945
gene id: 588898:BB347_RS01945
uniprot id: A0A1N6Z3T6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

588898:BB347 RS13395
gene id: 588898:BB347_RS13395
uniprot id: A0A1N7F449
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS16320
gene id: 588898:BB347_RS16320
uniprot id: A0A1N7AAV6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

588898:BB347 RS09325
gene id: 588898:BB347_RS09325
uniprot id: A0A1N7C9I8
names: Subcellular Location Annotation
messages: Cytoplasm

588898:BB347 RS04940
gene id: 588898:BB347_RS04940
uniprot id: A0A1N6X8H7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

588898:BB347 RS03790
gene id: 588898:BB347_RS03790
uniprot id: A0A1N6Y1I8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

588898:BB347 RS00760
gene id: 588898:BB347_RS00760
uniprot id: A0A1N6ZTV8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

588898:BB347 RS05855
gene id: 588898:BB347_RS05855
uniprot id: A0A1N7DUN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

588898:BB347 RS02995
gene id: 588898:BB347_RS02995
uniprot id: A0A1N6YHQ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS10240
gene id: 588898:BB347_RS10240
uniprot id: A0A1N7CMG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

588898:BB347 RS12235
gene id: 588898:BB347_RS12235
uniprot id: A0A1N7FQ49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

588898:BB347 RS13965
gene id: 588898:BB347_RS13965
uniprot id: A0A1N7F9G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

588898:BB347 RS13960
gene id: 588898:BB347_RS13960
uniprot id: A0A1N7F9D6
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS04210
gene id: 588898:BB347_RS04210
uniprot id: A0A1N6XR14
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

588898:BB347 RS07925
gene id: 588898:BB347_RS07925
uniprot id: A0A1N7BPN3
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

588898:BB347 RS01155
gene id: 588898:BB347_RS01155
uniprot id: A0A1N6ZJV0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS04055
gene id: 588898:BB347_RS04055
uniprot id: A0A1P8RB19
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS00770
gene id: 588898:BB347_RS00770
uniprot id: A0A1N6ZTM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

588898:BB347 RS01285
gene id: 588898:BB347_RS01285
uniprot id: A0A1N6ZGZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

588898:BB347 RS07215
gene id: 588898:BB347_RS07215
uniprot id: A0A1N7E8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

588898:BB347 RS03905
gene id: 588898:BB347_RS03905
uniprot id: A0A1N6XYS9
names: Similarity
messages: Belongs to the thioesterase PaaI family.

588898:BB347 RS13870
gene id: 588898:BB347_RS13870
uniprot id: A0A1N7F8F4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

588898:BB347 RS01590
gene id: 588898:BB347_RS01590
uniprot id: A0A1N6ZAM8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

588898:BB347 RS06500
gene id: 588898:BB347_RS06500
uniprot id: A0A1N7E173
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

588898:BB347 RS06905
gene id: 588898:BB347_RS06905
uniprot id: A0A1N7E566
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS12520
gene id: 588898:BB347_RS12520
uniprot id: A0A1N7FRX3
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

588898:BB347 RS02775
gene id: 588898:BB347_RS02775
uniprot id: A0A1N6YMB8
names: Similarity
messages: Belongs to the glutaredoxin family.

588898:BB347 RS09415
gene id: 588898:BB347_RS09415
uniprot id: A0A1N7CAU2
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS04060
gene id: 588898:BB347_RS04060
uniprot id: A0A1N6XUN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ModE family.
messages: Membrane

588898:BB347 RS13280
gene id: 588898:BB347_RS13280
uniprot id: A0A1N7F2X8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS06555
gene id: 588898:BB347_RS06555
uniprot id: A0A1N7E1G5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

588898:BB347 RS07220
gene id: 588898:BB347_RS07220
uniprot id: A0A1N7E8T3
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

588898:BB347 RS01070
gene id: 588898:BB347_RS01070
uniprot id: A0A1N6ZLY2
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

588898:BB347 RS07910
gene id: 588898:BB347_RS07910
uniprot id: A0A1N7BPL4
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

588898:BB347 RS06540
gene id: 588898:BB347_RS06540
uniprot id: A0A1N7E1C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

588898:BB347 RS07245
gene id: 588898:BB347_RS07245
uniprot id: A0A1N7E8Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

588898:BB347 RS12450
gene id: 588898:BB347_RS12450
uniprot id: A0A1N7FR55
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

588898:BB347 RS16365
gene id: 588898:BB347_RS16365
uniprot id: A0A1N7A9X7
names: Similarity
messages: Belongs to the PdaD family.

588898:BB347 RS04820
gene id: 588898:BB347_RS04820
uniprot id: A0A1N6XBG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

588898:BB347 RS14595
gene id: 588898:BB347_RS14595
uniprot id: A0A1N7ESG0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

588898:BB347 RS04320
gene id: 588898:BB347_RS04320
uniprot id: A0A1N6XNM3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

588898:BB347 RS06470
gene id: 588898:BB347_RS06470
uniprot id: A0A1N7E104
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

588898:BB347 RS14475
gene id: 588898:BB347_RS14475
uniprot id: A0A1N7ETI6
names: Similarity
messages: Belongs to the TPP enzyme family.

588898:BB347 RS05400
gene id: 588898:BB347_RS05400
uniprot id: A0A1N7DPI0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS01565
gene id: 588898:BB347_RS01565
uniprot id: A0A1N6ZB35
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

588898:BB347 RS06265
gene id: 588898:BB347_RS06265
uniprot id: A0A1N7DZ63
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS14195
gene id: 588898:BB347_RS14195
uniprot id: A0A1N7FBE2
names: Similarity
messages: Belongs to the peptidase S8 family.

588898:BB347 RS06765
gene id: 588898:BB347_RS06765
uniprot id: A0A1N7E3Q5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

588898:BB347 RS07210
gene id: 588898:BB347_RS07210
uniprot id: A0A1N7E8H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

588898:BB347 RS09585
gene id: 588898:BB347_RS09585
uniprot id: A0A1N7CDV3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

588898:BB347 RS12115
gene id: 588898:BB347_RS12115
uniprot id: A0A1N7G9E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

588898:BB347 RS10200
gene id: 588898:BB347_RS10200
uniprot id: A0A1N7CLX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

588898:BB347 RS13855
gene id: 588898:BB347_RS13855
uniprot id: A0A1N7F8C0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

588898:BB347 RS13390
gene id: 588898:BB347_RS13390
uniprot id: A0A1N7F417
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS14760
gene id: 588898:BB347_RS14760
uniprot id: A0A1N7ER45
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

588898:BB347 RS02105
gene id: 588898:BB347_RS02105
uniprot id: A0A1N6Z0R6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

588898:BB347 RS12830
gene id: 588898:BB347_RS12830
uniprot id: A0A1N7FTW7
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

588898:BB347 RS01745
gene id: 588898:BB347_RS01745
uniprot id: A0A1N6Z7B1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

588898:BB347 RS02965
gene id: 588898:BB347_RS02965
uniprot id: A0A1N6YIC1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

588898:BB347 RS04660
gene id: 588898:BB347_RS04660
uniprot id: A0A1N6XFL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

588898:BB347 RS15305
gene id: 588898:BB347_RS15305
uniprot id: A0A1N7ELI0
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

588898:BB347 RS01245
gene id: 588898:BB347_RS01245
uniprot id: A0A1N6ZHZ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

588898:BB347 RS07400
gene id: 588898:BB347_RS07400
uniprot id: A0A1P8RCT5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

588898:BB347 RS03805
gene id: 588898:BB347_RS03805
uniprot id: A0A1N6Y0V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

588898:BB347 RS05240
gene id: 588898:BB347_RS05240
uniprot id: A0A1N7DMM8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS07505
gene id: 588898:BB347_RS07505
uniprot id: A0A1N7EBM1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS14335
gene id: 588898:BB347_RS14335
uniprot id: A0A1N7EV23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS05615
gene id: 588898:BB347_RS05615
uniprot id: A0A1N7DS13
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS13765
gene id: 588898:BB347_RS13765
uniprot id: A0A1N7F7Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

588898:BB347 RS08375
gene id: 588898:BB347_RS08375
uniprot id: A0A1N7BX40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

588898:BB347 RS07320
gene id: 588898:BB347_RS07320
uniprot id: A0A1P8RHM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS05625
gene id: 588898:BB347_RS05625
uniprot id: A0A1P8RC88
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

588898:BB347 RS00100
gene id: 588898:BB347_RS00100
uniprot id: A0A1N7A6T9
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS07480
gene id: 588898:BB347_RS07480
uniprot id: A0A1N7EB81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

588898:BB347 RS09050
gene id: 588898:BB347_RS09050
uniprot id: A0A1N7C5I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Nucleus

588898:BB347 RS14460
gene id: 588898:BB347_RS14460
uniprot id: A0A1N7EU29
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS16715
gene id: 588898:BB347_RS16715
uniprot id: A0A1N7FKE1
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

588898:BB347 RS00360
gene id: 588898:BB347_RS00360
uniprot id: A0A1N7A1E3
names: Similarity
messages: Belongs to the Ahb/Nir family.

588898:BB347 RS15020
gene id: 588898:BB347_RS15020
uniprot id: A0A1N7EPB8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS00905
gene id: 588898:BB347_RS00905
uniprot id: A0A1N6ZQV1
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

588898:BB347 RS06060
gene id: 588898:BB347_RS06060
uniprot id: A0A1N7DWN9
names: Similarity
messages: Belongs to the asparaginase 1 family.

588898:BB347 RS14205
gene id: 588898:BB347_RS14205
uniprot id: A0A1N7FBK7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS10235
gene id: 588898:BB347_RS10235
uniprot id: A0A1N7CMA0
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS10545
gene id: 588898:BB347_RS10545
uniprot id: A0A1N7CR37
names: Similarity
messages: Belongs to the AOR/FOR family.

588898:BB347 RS12525
gene id: 588898:BB347_RS12525
uniprot id: A0A1N7FRV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

588898:BB347 RS05505
gene id: 588898:BB347_RS05505
uniprot id: A0A1N7DQT4
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS05835
gene id: 588898:BB347_RS05835
uniprot id: A0A1N7DUF4
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

588898:BB347 RS00780
gene id: 588898:BB347_RS00780
uniprot id: A0A1N6ZT99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

588898:BB347 RS06040
gene id: 588898:BB347_RS06040
uniprot id: A0A1N7DWJ7
names: Subcellular Location Annotation
messages: Cell membrane

588898:BB347 RS08825
gene id: 588898:BB347_RS08825
uniprot id: A0A1N7C2Z0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

588898:BB347 RS13940
gene id: 588898:BB347_RS13940
uniprot id: A0A1N7F906
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS08245
gene id: 588898:BB347_RS08245
uniprot id: A0A1N7BUZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

588898:BB347 RS10050
gene id: 588898:BB347_RS10050
uniprot id: A0A1N7CJL8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

588898:BB347 RS14915
gene id: 588898:BB347_RS14915
uniprot id: A0A1N7EPV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

588898:BB347 RS04460
gene id: 588898:BB347_RS04460
uniprot id: A0A1N6XKM5
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS14690
gene id: 588898:BB347_RS14690
uniprot id: A0A1N7ERN9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

588898:BB347 RS13020
gene id: 588898:BB347_RS13020
uniprot id: A0A1N7F094
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

588898:BB347 RS12835
gene id: 588898:BB347_RS12835
uniprot id: A0A1N7FTT1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

588898:BB347 RS06580
gene id: 588898:BB347_RS06580
uniprot id: A0A1N7E1W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

588898:BB347 RS02815
gene id: 588898:BB347_RS02815
uniprot id: A0A1N6YLD5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

588898:BB347 RS04730
gene id: 588898:BB347_RS04730
uniprot id: A0A1N6XDM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

588898:BB347 RS05490
gene id: 588898:BB347_RS05490
uniprot id: A0A1N7DQM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

588898:BB347 RS08275
gene id: 588898:BB347_RS08275
uniprot id: A0A1N7BV77
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

588898:BB347 RS06405
gene id: 588898:BB347_RS06405
uniprot id: A0A1N7E0G1
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS08115
gene id: 588898:BB347_RS08115
uniprot id: A0A1N7BSJ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS01330
gene id: 588898:BB347_RS01330
uniprot id: A0A1N6ZG71
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

588898:BB347 RS12905
gene id: 588898:BB347_RS12905
uniprot id: A0A1N7FUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

588898:BB347 RS03740
gene id: 588898:BB347_RS03740
uniprot id: A0A1N6Y2K9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

588898:BB347 RS01705
gene id: 588898:BB347_RS01705
uniprot id: A0A1N6Z849
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS02190
gene id: 588898:BB347_RS02190
uniprot id: A0A1N6YYW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

588898:BB347 RS00025
gene id: 588898:BB347_RS00025
uniprot id: A0A1N7A845
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

588898:BB347 RS14165
gene id: 588898:BB347_RS14165
uniprot id: A0A1N7FBB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

588898:BB347 RS15570
gene id: 588898:BB347_RS15570
uniprot id: A0A1N7APT6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

588898:BB347 RS02790
gene id: 588898:BB347_RS02790
uniprot id: A0A1N6YM21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS00180
gene id: 588898:BB347_RS00180
uniprot id: A0A1N7A533
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS08100
gene id: 588898:BB347_RS08100
uniprot id: A0A1N7BSB3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

588898:BB347 RS08875
gene id: 588898:BB347_RS08875
uniprot id: A0A1N7C3B1
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS09170
gene id: 588898:BB347_RS09170
uniprot id: A0A1N7C7M0
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS02710
gene id: 588898:BB347_RS02710
uniprot id: A0A1N6YN68
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS03220
gene id: 588898:BB347_RS03220
uniprot id: A0A1N6YD24
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

588898:BB347 RS05010
gene id: 588898:BB347_RS05010
uniprot id: A0A1N6X6T7
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

588898:BB347 RS01345
gene id: 588898:BB347_RS01345
uniprot id: A0A1P8R9L1
names: Similarity
messages: Belongs to the NAD synthetase family.

588898:BB347 RS00920
gene id: 588898:BB347_RS00920
uniprot id: A0A1N6ZQH3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

588898:BB347 RS14820
gene id: 588898:BB347_RS14820
uniprot id: A0A1N7EQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

588898:BB347 RS09495
gene id: 588898:BB347_RS09495
uniprot id: A0A1N7CC48
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

588898:BB347 RS03605
gene id: 588898:BB347_RS03605
uniprot id: A0A1N6Y5P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

588898:BB347 RS13510
gene id: 588898:BB347_RS13510
uniprot id: A0A1N7F5C0
names: Similarity
messages: Belongs to the HMBS family.

588898:BB347 RS09595
gene id: 588898:BB347_RS09595
uniprot id: A0A1P8RHV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylamine corrinoid protein family.
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

588898:BB347 RS08695
gene id: 588898:BB347_RS08695
uniprot id: A0A1N7C0U9
names: Similarity
messages: Belongs to the pirin family.

588898:BB347 RS02485
gene id: 588898:BB347_RS02485
uniprot id: A0A1N6YT95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS03700
gene id: 588898:BB347_RS03700
uniprot id: A0A1N6Y3N7
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

588898:BB347 RS12020
gene id: 588898:BB347_RS12020
uniprot id: A0A1N7G8M7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

588898:BB347 RS10045
gene id: 588898:BB347_RS10045
uniprot id: A0A1N7CK21
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

588898:BB347 RS09160
gene id: 588898:BB347_RS09160
uniprot id: A0A1N7C7Q2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

588898:BB347 RS07810
gene id: 588898:BB347_RS07810
uniprot id: A0A1N7BMX3
names: Similarity
messages: Belongs to the PEPCase type 1 family.

588898:BB347 RS11595
gene id: 588898:BB347_RS11595
uniprot id: A0A1N7D526
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS03640
gene id: 588898:BB347_RS03640
uniprot id: A0A1N6Y4U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

588898:BB347 RS07890
gene id: 588898:BB347_RS07890
uniprot id: A0A1N7BPC7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

588898:BB347 RS16400
gene id: 588898:BB347_RS16400
uniprot id: A0A1N7A989
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

588898:BB347 RS05090
gene id: 588898:BB347_RS05090
uniprot id: A0A1N6X558
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

588898:BB347 RS08030
gene id: 588898:BB347_RS08030
uniprot id: A0A1N7BRL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS17900
gene id: 588898:BB347_RS17900
uniprot id: A0A1N7FYZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS07195
gene id: 588898:BB347_RS07195
uniprot id: A0A1N7E8N4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

588898:BB347 RS15980
gene id: 588898:BB347_RS15980
uniprot id: A0A1N7AGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

588898:BB347 RS17990
gene id: 588898:BB347_RS17990
uniprot id: A0A1N7FZK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

588898:BB347 RS11855
gene id: 588898:BB347_RS11855
uniprot id: A0A1N7D7H2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS13220
gene id: 588898:BB347_RS13220
uniprot id: A0A1N7F2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

588898:BB347 RS09675
gene id: 588898:BB347_RS09675
uniprot id: A0A1N7CEL1
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS07965
gene id: 588898:BB347_RS07965
uniprot id: A0A1N7BQ73
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS17235
gene id: 588898:BB347_RS17235
uniprot id: A0A1N7FHI6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

588898:BB347 RS12435
gene id: 588898:BB347_RS12435
uniprot id: A0A1N7FR34
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS01165
gene id: 588898:BB347_RS01165
uniprot id: A0A1N6ZJU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

588898:BB347 RS00015
gene id: 588898:BB347_RS00015
uniprot id: A0A1N7A843
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

588898:BB347 RS03085
gene id: 588898:BB347_RS03085
uniprot id: A0A1N6YFU1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

588898:BB347 RS02855
gene id: 588898:BB347_RS02855
uniprot id: A0A1N6YKG0
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS13310
gene id: 588898:BB347_RS13310
uniprot id: A0A1N7F3F3
names: Similarity
messages: Belongs to the SUI1 family.

588898:BB347 RS07535
gene id: 588898:BB347_RS07535
uniprot id: A0A1N7EBS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

588898:BB347 RS10400
gene id: 588898:BB347_RS10400
uniprot id: A0A1N7CPR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cell membrane
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Membrane
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

588898:BB347 RS07690
gene id: 588898:BB347_RS07690
uniprot id: A0A1N7EDF5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

588898:BB347 RS00775
gene id: 588898:BB347_RS00775
uniprot id: A0A1N6ZTG5
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS12160
gene id: 588898:BB347_RS12160
uniprot id: A0A1N7FP80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

588898:BB347 RS16415
gene id: 588898:BB347_RS16415
uniprot id: A0A1N7A8X8
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

588898:BB347 RS07745
gene id: 588898:BB347_RS07745
uniprot id: A0A1N7EDV7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

588898:BB347 RS06610
gene id: 588898:BB347_RS06610
uniprot id: A0A1N7E2C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

588898:BB347 RS01835
gene id: 588898:BB347_RS01835
uniprot id: A0A1N6Z5M8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

588898:BB347 RS06285
gene id: 588898:BB347_RS06285
uniprot id: A0A1P8RC62
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

588898:BB347 RS14765
gene id: 588898:BB347_RS14765
uniprot id: A0A1N7EQW6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

588898:BB347 RS10035
gene id: 588898:BB347_RS10035
uniprot id: A0A1N7CJT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

588898:BB347 RS00110
gene id: 588898:BB347_RS00110
uniprot id: A0A1N7A6H3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS00230
gene id: 588898:BB347_RS00230
uniprot id: A0A1N7A424
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS17335
gene id: 588898:BB347_RS17335
uniprot id: A0A1N7FIF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

588898:BB347 RS08750
gene id: 588898:BB347_RS08750
uniprot id: A0A1N7C1Z6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS11090
gene id: 588898:BB347_RS11090
uniprot id: A0A1N7CYL1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

588898:BB347 RS07090
gene id: 588898:BB347_RS07090
uniprot id: A0A1P8RCI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

588898:BB347 RS07640
gene id: 588898:BB347_RS07640
uniprot id: A0A1N7ECZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Homodimer.

588898:BB347 RS08760
gene id: 588898:BB347_RS08760
uniprot id: A0A1N7C1R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

588898:BB347 RS04785
gene id: 588898:BB347_RS04785
uniprot id: A0A1N6XCP0
names: Similarity
messages: Belongs to the isochorismate synthase family.

588898:BB347 RS14285
gene id: 588898:BB347_RS14285
uniprot id: A0A1N7EVK2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

588898:BB347 RS05630
gene id: 588898:BB347_RS05630
uniprot id: A0A1N7DS62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS09580
gene id: 588898:BB347_RS09580
uniprot id: A0A1N7CDT2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

588898:BB347 RS05585
gene id: 588898:BB347_RS05585
uniprot id: A0A1N7DS77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

588898:BB347 RS02810
gene id: 588898:BB347_RS02810
uniprot id: A0A1N6YLA0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

588898:BB347 RS08390
gene id: 588898:BB347_RS08390
uniprot id: A0A1N7BX02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

588898:BB347 RS09470
gene id: 588898:BB347_RS09470
uniprot id: A0A1N7CBN0
names: Function
names: Similarity
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

588898:BB347 RS09175
gene id: 588898:BB347_RS09175
uniprot id: A0A1N7C7J1
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

588898:BB347 RS10575
gene id: 588898:BB347_RS10575
uniprot id: A0A1N7CRD3
names: Similarity
messages: Belongs to the peptidase S9C family.

588898:BB347 RS08430
gene id: 588898:BB347_RS08430
uniprot id: A0A1N7BXK5
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS13295
gene id: 588898:BB347_RS13295
uniprot id: A0A1N7F341
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

588898:BB347 RS04445
gene id: 588898:BB347_RS04445
uniprot id: A0A1P8RB75
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS10445
gene id: 588898:BB347_RS10445
uniprot id: A0A1N7CQ34
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

588898:BB347 RS06450
gene id: 588898:BB347_RS06450
uniprot id: A0A1N7E0M7
names: Similarity
messages: Belongs to the NodU/CmcH family.

588898:BB347 RS06750
gene id: 588898:BB347_RS06750
uniprot id: A0A1N7E3N8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

588898:BB347 RS13445
gene id: 588898:BB347_RS13445
uniprot id: A0A1P8RHW8
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

588898:BB347 RS05045
gene id: 588898:BB347_RS05045
uniprot id: A0A1N6X638
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS04090
gene id: 588898:BB347_RS04090
uniprot id: A0A1N6XU05
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

588898:BB347 RS07110
gene id: 588898:BB347_RS07110
uniprot id: A0A1N7E7H3
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS03625
gene id: 588898:BB347_RS03625
uniprot id: A0A1N6Y533
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

588898:BB347 RS11725
gene id: 588898:BB347_RS11725
uniprot id: A0A1N7D5U5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

588898:BB347 RS04330
gene id: 588898:BB347_RS04330
uniprot id: A0A1N6XND3
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

588898:BB347 RS07460
gene id: 588898:BB347_RS07460
uniprot id: A0A1N7EB70
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

588898:BB347 RS01095
gene id: 588898:BB347_RS01095
uniprot id: A0A1N6ZLH6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

588898:BB347 RS07430
gene id: 588898:BB347_RS07430
uniprot id: A0A1N7EAZ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

588898:BB347 RS05850
gene id: 588898:BB347_RS05850
uniprot id: A0A1N7DUK9
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

588898:BB347 RS02980
gene id: 588898:BB347_RS02980
uniprot id: A0A1N6YI23
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

588898:BB347 RS03050
gene id: 588898:BB347_RS03050
uniprot id: A0A1N6YGQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

588898:BB347 RS08090
gene id: 588898:BB347_RS08090
uniprot id: A0A1N7BSD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

588898:BB347 RS00380
gene id: 588898:BB347_RS00380
uniprot id: A0A1N7A0N6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

588898:BB347 RS11965
gene id: 588898:BB347_RS11965
uniprot id: A0A1N7G8B6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

588898:BB347 RS00405
gene id: 588898:BB347_RS00405
uniprot id: A0A1N7A0G9
names: Subcellular Location Annotation
messages: Membrane

588898:BB347 RS01115
gene id: 588898:BB347_RS01115
uniprot id: A0A1N6ZL12
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

588898:BB347 RS08535
gene id: 588898:BB347_RS08535
uniprot id: A0A1N7BYN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

588898:BB347 RS00665
gene id: 588898:BB347_RS00665
uniprot id: A0A1N6ZV47
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.