5861:PY17X 1013500
gene id: 5861:PY17X_1013500
uniprot id: A0A078KEW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF-assemblin family.
messages: cytoskeleton

5861:PY17X 1337600
gene id: 5861:PY17X_1337600
uniprot id: A0A078KGZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

5861:PY17X 0715000
gene id: 5861:PY17X_0715000
uniprot id: A0A078K2Q0
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0211600
gene id: 5861:PY17X_0211600
uniprot id: A0A077Y0G3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

5861:PY17X 1007500
gene id: 5861:PY17X_1007500
uniprot id: A0A077YEJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Mitochondrion
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

5861:PY17X 1418600
gene id: 5861:PY17X_1418600
uniprot id: A0A077YBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

5861:PY17X 1230000
gene id: 5861:PY17X_1230000
uniprot id: A0A077Y7P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

5861:PY17X 1135100
gene id: 5861:PY17X_1135100
uniprot id: A0A078KCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

5861:PY17X 1407500
gene id: 5861:PY17X_1407500
uniprot id: A0A078KBE4
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

5861:PY17X 1461800
gene id: 5861:PY17X_1461800
uniprot id: A0A078K9W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Cytoplasm

5861:PY17X 0409200
gene id: 5861:PY17X_0409200
uniprot id: A0A077Y275
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

5861:PY17X 0935700
gene id: 5861:PY17X_0935700
uniprot id: A0A077Y535
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

5861:PY17X 0104600
gene id: 5861:PY17X_0104600
uniprot id: A0A078K2W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

5861:PY17X 1417300
gene id: 5861:PY17X_1417300
uniprot id: A0A077YCQ0
names: Function
names: Similarity
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.

5861:PY17X 0810300
gene id: 5861:PY17X_0810300
uniprot id: A0A078K949
names: Similarity
messages: Belongs to the band 7/mec-2 family.

5861:PY17X 1127600
gene id: 5861:PY17X_1127600
uniprot id: A0A077Y687
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

5861:PY17X 1425700
gene id: 5861:PY17X_1425700
uniprot id: A0A078KFA9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

5861:PY17X 1323600
gene id: 5861:PY17X_1323600
uniprot id: A0A078KGI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHMT family.
messages: Cytoplasm

5861:PY17X 0316500
gene id: 5861:PY17X_0316500
uniprot id: A0A077XZP3
names: Similarity
messages: Belongs to the RAMP4 family.

5861:PY17X 0205700
gene id: 5861:PY17X_0205700
uniprot id: A0A077XZP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

5861:PY17X 1237300
gene id: 5861:PY17X_1237300
uniprot id: A0A077Y816
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

5861:PY17X 1336700
gene id: 5861:PY17X_1336700
uniprot id: A0A078KKY5
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0112800
gene id: 5861:PY17X_0112800
uniprot id: A0A077XZA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

5861:PY17X 0927200
gene id: 5861:PY17X_0927200
uniprot id: A0A077Y4V0
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.

5861:PY17X 1344900
gene id: 5861:PY17X_1344900
uniprot id: A0A077YD21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

5861:PY17X 0315200
gene id: 5861:PY17X_0315200
uniprot id: A0A078K457
names: Similarity
messages: Belongs to the activator 1 small subunits family.

5861:PY17X 0619900
gene id: 5861:PY17X_0619900
uniprot id: A0A078KAL2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

5861:PY17X 1026200
gene id: 5861:PY17X_1026200
uniprot id: A0A078KCL2
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

5861:PY17X 0316600
gene id: 5861:PY17X_0316600
uniprot id: A0A078K6W2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

5861:PY17X 1102700
gene id: 5861:PY17X_1102700
uniprot id: A0A077Y5Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

5861:PY17X 1323000
gene id: 5861:PY17X_1323000
uniprot id: A0A077Y9J6
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

5861:PY17X 1433600
gene id: 5861:PY17X_1433600
uniprot id: A0A077YBZ0
names: Similarity
messages: Belongs to the SDHAF4 family.

5861:PY17X 1124300
gene id: 5861:PY17X_1124300
uniprot id: A0A078K963
names: Similarity
messages: Belongs to the hexokinase family.

5861:PY17X 1120200
gene id: 5861:PY17X_1120200
uniprot id: A0A078KC50
names: Similarity
messages: Belongs to the SF3A2 family.

5861:PY17X 0604800
gene id: 5861:PY17X_0604800
uniprot id: A0A077Y2J4
names: Similarity
messages: Belongs to the TBCC family.

5861:PY17X 0108700
gene id: 5861:PY17X_0108700
uniprot id: A0A077XZT8
names: Similarity
messages: Belongs to the peptidase T1A family.

5861:PY17X 1424700
gene id: 5861:PY17X_1424700
uniprot id: A0A077YBF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Cytoplasm
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homodimer.

5861:PY17X 0917200
gene id: 5861:PY17X_0917200
uniprot id: A0A078K7F4
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

5861:PY17X 1339300
gene id: 5861:PY17X_1339300
uniprot id: A0A078KKT2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

5861:PY17X 1246200
gene id: 5861:PY17X_1246200
uniprot id: A0A077Y945
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

5861:PY17X 1037900
gene id: 5861:PY17X_1037900
uniprot id: A0A078KFN6
names: Similarity
messages: Belongs to the VPS29 family.

5861:PY17X 1035000
gene id: 5861:PY17X_1035000
uniprot id: A0A077YFD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

5861:PY17X 0306300
gene id: 5861:PY17X_0306300
uniprot id: A0A078K6N3
names: Similarity
messages: Belongs to the RRF family.

5861:PY17X 1305500
gene id: 5861:PY17X_1305500
uniprot id: A0A077Y8I6
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0924900
gene id: 5861:PY17X_0924900
uniprot id: A0A4V0KL67
names: Similarity
messages: Belongs to the Tim44 family.

5861:PY17X 1435300
gene id: 5861:PY17X_1435300
uniprot id: A0A078KFL7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.

5861:PY17X 1145800
gene id: 5861:PY17X_1145800
uniprot id: A0A077Y7S2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

5861:PY17X 0510900
gene id: 5861:PY17X_0510900
uniprot id: A0A078K586
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

5861:PY17X 0109000
gene id: 5861:PY17X_0109000
uniprot id: A0A077XYA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Cytoplasm

5861:PY17X 0825000
gene id: 5861:PY17X_0825000
uniprot id: A0A078K6H9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

5861:PY17X 0812400
gene id: 5861:PY17X_0812400
uniprot id: A0A078K373
names: Similarity
messages: Belongs to the PA28 family.

5861:PY17X 1344800
gene id: 5861:PY17X_1344800
uniprot id: A0A077Y9S7
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

5861:PY17X 0414900
gene id: 5861:PY17X_0414900
uniprot id: A0A078K7C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

5861:PY17X 0916500
gene id: 5861:PY17X_0916500
uniprot id: A0A078KAI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apicomplexan parasites AMA1 family.
messages: Membrane

5861:PY17X 1016300
gene id: 5861:PY17X_1016300
uniprot id: A0A077YH97
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

5861:PY17X 1210100
gene id: 5861:PY17X_1210100
uniprot id: A0A078K9Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

5861:PY17X 1411600
gene id: 5861:PY17X_1411600
uniprot id: A0A077YBA8
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

5861:PY17X 1330200
gene id: 5861:PY17X_1330200
uniprot id: A0A078KKR9
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

5861:PY17X 1459400
gene id: 5861:PY17X_1459400
uniprot id: A0A077YFQ1
names: Similarity
messages: Belongs to the SUI1 family.

5861:PY17X 1452600
gene id: 5861:PY17X_1452600
uniprot id: A0A078KG37
names: Similarity
messages: Belongs to the MT-A70-like family.

5861:PY17X 1438100
gene id: 5861:PY17X_1438100
uniprot id: A0A077YF48
names: Function
names: Similarity
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.

5861:PY17X 1368300
gene id: 5861:PY17X_1368300
uniprot id: A0A078KLF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

5861:PY17X 1243100
gene id: 5861:PY17X_1243100
uniprot id: A0A078KEB4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

5861:PY17X 1018500
gene id: 5861:PY17X_1018500
uniprot id: A0A078KF04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane
messages: Mitochondrion inner membrane

5861:PY17X 1325200
gene id: 5861:PY17X_1325200
uniprot id: A0A078KKL5
names: Similarity
messages: Belongs to the CBF/MAK21 family.

5861:PY17X 1336200
gene id: 5861:PY17X_1336200
uniprot id: A0A078KKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TLS1 family.
messages: Nucleus

5861:PY17X 1306600
gene id: 5861:PY17X_1306600
uniprot id: Q86SB2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

5861:PY17X 0524500
gene id: 5861:PY17X_0524500
uniprot id: A0A4V0KH13
names: Similarity
messages: Belongs to the DEAD box helicase family.

5861:PY17X 1136600
gene id: 5861:PY17X_1136600
uniprot id: A0A078KCV3
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

5861:PY17X 0311100
gene id: 5861:PY17X_0311100
uniprot id: A0A077Y1R7
names: Similarity
messages: Belongs to the FAM136 family.

5861:PY17X 1240500
gene id: 5861:PY17X_1240500
uniprot id: A0A078KB01
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

5861:PY17X 0312900
gene id: 5861:PY17X_0312900
uniprot id: A0A078K6B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: apicoplast

5861:PY17X 0513000
gene id: 5861:PY17X_0513000
uniprot id: A0A077Y0U5
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

5861:PY17X 1133000
gene id: 5861:PY17X_1133000
uniprot id: A0A077Y6E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

5861:PY17X 0408600
gene id: 5861:PY17X_0408600
uniprot id: A0A077Y268
names: Similarity
messages: Belongs to the DNA polymerase delta/II small subunit family.

5861:PY17X 0808200
gene id: 5861:PY17X_0808200
uniprot id: A0A078K932
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

5861:PY17X 0924800
gene id: 5861:PY17X_0924800
uniprot id: A0A078K4M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures.
messages: Nucleus

5861:PY17X 0517500
gene id: 5861:PY17X_0517500
uniprot id: A0A077Y5B4
names: Similarity
messages: Belongs to the RMD1/sif2 family.

5861:PY17X 1004100
gene id: 5861:PY17X_1004100
uniprot id: A0A077YGW8
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

5861:PY17X 1144900
gene id: 5861:PY17X_1144900
uniprot id: A0A078K9J1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Mitochondrion
messages: Monomer.

5861:PY17X 1239000
gene id: 5861:PY17X_1239000
uniprot id: A0A078KAY6
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

5861:PY17X 1209300
gene id: 5861:PY17X_1209300
uniprot id: A0A078KDF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

5861:PY17X 0215800
gene id: 5861:PY17X_0215800
uniprot id: A0A078K5Z9
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0208600
gene id: 5861:PY17X_0208600
uniprot id: A0A078K3J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

5861:PY17X 0307500
gene id: 5861:PY17X_0307500
uniprot id: A0A077Y0D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

5861:PY17X 0822000
gene id: 5861:PY17X_0822000
uniprot id: A0A078K6E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

5861:PY17X 0514500
gene id: 5861:PY17X_0514500
uniprot id: A0A077Y0W0
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

5861:PY17X 0923100
gene id: 5861:PY17X_0923100
uniprot id: A0A4V0KMC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Nucleus

5861:PY17X 1412900
gene id: 5861:PY17X_1412900
uniprot id: A0A077YB02
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

5861:PY17X 1029400
gene id: 5861:PY17X_1029400
uniprot id: A0A077YGA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Cytoplasm

5861:PY17X 1352500
gene id: 5861:PY17X_1352500
uniprot id: A0A078KLG4
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

5861:PY17X 1360000
gene id: 5861:PY17X_1360000
uniprot id: A0A077Y9T0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

5861:PY17X 1015200
gene id: 5861:PY17X_1015200
uniprot id: A0A077YES8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

5861:PY17X 0606900
gene id: 5861:PY17X_0606900
uniprot id: A0A077Y3R6
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

5861:PY17X 1111900
gene id: 5861:PY17X_1111900
uniprot id: A0A077Y5X0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

5861:PY17X 0712800
gene id: 5861:PY17X_0712800
uniprot id: A0A077Y3H7
names: Similarity
messages: Belongs to the 14-3-3 family.

5861:PY17X 1411400
gene id: 5861:PY17X_1411400
uniprot id: A0A077YAY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus

5861:PY17X 0720300
gene id: 5861:PY17X_0720300
uniprot id: A0A078K900
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

5861:PY17X 0939000
gene id: 5861:PY17X_0939000
uniprot id: A0A078K880
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

5861:PY17X 1461400
gene id: 5861:PY17X_1461400
uniprot id: A0A077YCF3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

5861:PY17X 1431900
gene id: 5861:PY17X_1431900
uniprot id: A0A4V0KTQ0
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

5861:PY17X 0625100
gene id: 5861:PY17X_0625100
uniprot id: A0A077Y2P9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

5861:PY17X 0605100
gene id: 5861:PY17X_0605100
uniprot id: A0A077Y1C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

5861:PY17X 1230900
gene id: 5861:PY17X_1230900
uniprot id: A0A078KAK6
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

5861:PY17X 1120800
gene id: 5861:PY17X_1120800
uniprot id: A0A077YA24
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 1129200
gene id: 5861:PY17X_1129200
uniprot id: A0A077YAA8
names: Similarity
messages: Belongs to the NAPRTase family.

5861:PY17X 0112000
gene id: 5861:PY17X_0112000
uniprot id: A0A077XYD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

5861:PY17X 1233300
gene id: 5861:PY17X_1233300
uniprot id: A0A077Y7W2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

5861:PY17X 0103700
gene id: 5861:PY17X_0103700
uniprot id: A0A078K5G0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Mitochondrion inner membrane

5861:PY17X 1246700
gene id: 5861:PY17X_1246700
uniprot id: A0A078KB54
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

5861:PY17X 1407000
gene id: 5861:PY17X_1407000
uniprot id: A0A078KBE0
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0505200
gene id: 5861:PY17X_0505200
uniprot id: A0A078K1S8
names: Similarity
messages: Belongs to the ATG8 family.

5861:PY17X 0933200
gene id: 5861:PY17X_0933200
uniprot id: A0A077Y509
names: Similarity
messages: Belongs to the ClpA/ClpB family.

5861:PY17X 1118100
gene id: 5861:PY17X_1118100
uniprot id: A0A077Y7U9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

5861:PY17X 1036700
gene id: 5861:PY17X_1036700
uniprot id: A0A078KD02
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 1005200
gene id: 5861:PY17X_1005200
uniprot id: A0A077YF83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

5861:PY17X 1422600
gene id: 5861:PY17X_1422600
uniprot id: A0A077YBM3
names: Subcellular Location Annotation
messages: Membrane

5861:PY17X 1107600
gene id: 5861:PY17X_1107600
uniprot id: A0A077Y6K4
names: Subcellular Location Annotation
messages: Membrane

5861:PY17X 1415900
gene id: 5861:PY17X_1415900
uniprot id: A0A078KF17
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.

5861:PY17X 1325500
gene id: 5861:PY17X_1325500
uniprot id: A0A077Y9L7
names: Similarity
messages: Belongs to the peptidase C1 family.

5861:PY17X 0205600
gene id: 5861:PY17X_0205600
uniprot id: A0A078K3F3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: cytoskeleton

5861:PY17X 1206200
gene id: 5861:PY17X_1206200
uniprot id: A0A077Y717
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

5861:PY17X 0933300
gene id: 5861:PY17X_0933300
uniprot id: A0A077Y902
names: Similarity
messages: Belongs to the peptidase C1 family.

5861:PY17X 1367700
gene id: 5861:PY17X_1367700
uniprot id: A0A078KLT7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

5861:PY17X 1412200
gene id: 5861:PY17X_1412200
uniprot id: A0A078KBJ6
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

5861:PY17X 1402700
gene id: 5861:PY17X_1402700
uniprot id: A0A077YAN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

5861:PY17X 0931900
gene id: 5861:PY17X_0931900
uniprot id: A0A078K7S5
names: Similarity
messages: Belongs to the heat shock protein 90 family.

5861:PY17X 1139300
gene id: 5861:PY17X_1139300
uniprot id: A0A078K6E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

5861:PY17X 1322000
gene id: 5861:PY17X_1322000
uniprot id: A0A077Y9J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NifU family.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

5861:PY17X 0502300
gene id: 5861:PY17X_0502300
uniprot id: A0A077Y2P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

5861:PY17X 1006900
gene id: 5861:PY17X_1006900
uniprot id: A0A077YFP8
names: Similarity
messages: Belongs to the AAA ATPase family.

5861:PY17X 1458900
gene id: 5861:PY17X_1458900
uniprot id: A0A077YFP5
names: Similarity
messages: Belongs to the syntaxin family.

5861:PY17X 0618700
gene id: 5861:PY17X_0618700
uniprot id: A0A077Y440
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

5861:PY17X 1011100
gene id: 5861:PY17X_1011100
uniprot id: A0A078KIV4
names: Similarity
messages: Belongs to the glutamate synthase family.

5861:PY17X 0619500
gene id: 5861:PY17X_0619500
uniprot id: A0A078KDT8
names: Similarity
messages: Belongs to the actin family.

5861:PY17X 1213300
gene id: 5861:PY17X_1213300
uniprot id: A0A077Y932
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

5861:PY17X 0940800
gene id: 5861:PY17X_0940800
uniprot id: A0A077Y9A8
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays an important role in regulating the size of autophagosomes during the formation process.

5861:PY17X 0943700
gene id: 5861:PY17X_0943700
uniprot id: A0A077Y5C9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

5861:PY17X 1328700
gene id: 5861:PY17X_1328700
uniprot id: A0A078KKQ3
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

5861:PY17X 0806700
gene id: 5861:PY17X_0806700
uniprot id: A0A078K9F9
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

5861:PY17X 1426800
gene id: 5861:PY17X_1426800
uniprot id: A0A077YEU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

5861:PY17X 0833000
gene id: 5861:PY17X_0833000
uniprot id: A0A078K6Q6
names: Similarity
messages: Belongs to the guanylate kinase family.

5861:PY17X 1225700
gene id: 5861:PY17X_1225700
uniprot id: A0A078KAL0
names: Similarity
messages: Belongs to the peptidase A1 family.

5861:PY17X 0403200
gene id: 5861:PY17X_0403200
uniprot id: A0A077Y4A4
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

5861:PY17X 1024200
gene id: 5861:PY17X_1024200
uniprot id: A0A078KCI8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

5861:PY17X 1333000
gene id: 5861:PY17X_1333000
uniprot id: A0A078KGT3
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

5861:PY17X 1412000
gene id: 5861:PY17X_1412000
uniprot id: A0A078K8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Mitochondrion intermembrane space

5861:PY17X 0946300
gene id: 5861:PY17X_0946300
uniprot id: A0A077Y7E5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

5861:PY17X 1347600
gene id: 5861:PY17X_1347600
uniprot id: A0A077Y9K2
names: Similarity
messages: Belongs to the RENT3 family.

5861:PY17X 0718700
gene id: 5861:PY17X_0718700
uniprot id: A0A078K608
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Nucleus

5861:PY17X 1408500
gene id: 5861:PY17X_1408500
uniprot id: A0A078KBF4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

5861:PY17X 1210200
gene id: 5861:PY17X_1210200
uniprot id: A0A078KA43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

5861:PY17X 0906500
gene id: 5861:PY17X_0906500
uniprot id: A0A078K450
names: Function
names: Similarity
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.

5861:PY17X 1109000
gene id: 5861:PY17X_1109000
uniprot id: A0A077Y9R3
names: Subcellular Location Annotation
messages: Membrane

5861:PY17X 1123900
gene id: 5861:PY17X_1123900
uniprot id: A0A078KCK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

5861:PY17X 0410200
gene id: 5861:PY17X_0410200
uniprot id: A0A078K782
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

5861:PY17X 1335300
gene id: 5861:PY17X_1335300
uniprot id: A0A078KKN6
names: Similarity
messages: Belongs to the DXR family.

5861:PY17X 1318400
gene id: 5861:PY17X_1318400
uniprot id: A0A077YCC7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

5861:PY17X 1036000
gene id: 5861:PY17X_1036000
uniprot id: A0A077YFE1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

5861:PY17X 0103600
gene id: 5861:PY17X_0103600
uniprot id: A0A078K2V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

5861:PY17X 1418300
gene id: 5861:PY17X_1418300
uniprot id: A0A078KF62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2Fe2S plant-type ferredoxin family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

5861:PY17X 0305900
gene id: 5861:PY17X_0305900
uniprot id: A0A077Y0R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

5861:PY17X 1230700
gene id: 5861:PY17X_1230700
uniprot id: A0A078KDU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYF2 family.
messages: Nucleus

5861:PY17X 0830500
gene id: 5861:PY17X_0830500
uniprot id: A0A078K6N4
names: Subcellular Location Annotation
messages: Membrane

5861:PY17X 0405200
gene id: 5861:PY17X_0405200
uniprot id: A0A078K3W4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

5861:PY17X 1018200
gene id: 5861:PY17X_1018200
uniprot id: A0A078KIS4
names: Similarity
messages: Belongs to the ANP32 family.

5861:PY17X 1108700
gene id: 5861:PY17X_1108700
uniprot id: A0A078K8Q5
names: Subcellular Location Annotation
messages: Cell surface

5861:PY17X 1339900
gene id: 5861:PY17X_1339900
uniprot id: A0A077YCX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

5861:PY17X 0415000
gene id: 5861:PY17X_0415000
uniprot id: A0A078K726
names: Similarity
messages: Belongs to the PPP phosphatase family.

5861:PY17X 1361400
gene id: 5861:PY17X_1361400
uniprot id: A0A078KEW9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

5861:PY17X 1020100
gene id: 5861:PY17X_1020100
uniprot id: A0A078KJ65
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

5861:PY17X 0518900
gene id: 5861:PY17X_0518900
uniprot id: A0A078K5G3
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

5861:PY17X 0303100
gene id: 5861:PY17X_0303100
uniprot id: Q8I756
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

5861:PY17X 1411200
gene id: 5861:PY17X_1411200
uniprot id: A0A078KBI7
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

5861:PY17X 1411500
gene id: 5861:PY17X_1411500
uniprot id: A0A077YEA6
names: Similarity
messages: Belongs to the WD repeat SMU1 family.

5861:PY17X 1353500
gene id: 5861:PY17X_1353500
uniprot id: A0A077YBM9
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 1466100
gene id: 5861:PY17X_1466100
uniprot id: A0A078KGN9
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

5861:PY17X 1134800
gene id: 5861:PY17X_1134800
uniprot id: A0A078K9A3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

5861:PY17X 0508500
gene id: 5861:PY17X_0508500
uniprot id: A0A077Y0Q9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

5861:PY17X 1127000
gene id: 5861:PY17X_1127000
uniprot id: A0A077Y682
names: Similarity
messages: Belongs to the pyruvate kinase family.

5861:PY17X 1422800
gene id: 5861:PY17X_1422800
uniprot id: A0A077YCV8
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 1039000
gene id: 5861:PY17X_1039000
uniprot id: A0A078KJP8
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

5861:PY17X 0103500
gene id: 5861:PY17X_0103500
uniprot id: A0A078K264
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF-assemblin family.
messages: cytoskeleton

5861:PY17X 1019200
gene id: 5861:PY17X_1019200
uniprot id: A0A077YF09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRH/QCR6 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

5861:PY17X 0113400
gene id: 5861:PY17X_0113400
uniprot id: A0A077Y0P7
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

5861:PY17X 0708600
gene id: 5861:PY17X_0708600
uniprot id: A0A077Y270
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

5861:PY17X 0215000
gene id: 5861:PY17X_0215000
uniprot id: A0A077Y3L1
names: Similarity
messages: Belongs to the MT-A70-like family.

5861:PY17X 0824400
gene id: 5861:PY17X_0824400
uniprot id: A0A077Y7L9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

5861:PY17X 1111200
gene id: 5861:PY17X_1111200
uniprot id: A0A077Y5W6
names: Similarity
messages: Belongs to the type IB topoisomerase family.

5861:PY17X 0912800
gene id: 5861:PY17X_0912800
uniprot id: A0A077Y6L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

5861:PY17X 0307800
gene id: 5861:PY17X_0307800
uniprot id: A0A077Y3V6
names: Subcellular Location Annotation
messages: Membrane

5861:PY17X 1206900
gene id: 5861:PY17X_1206900
uniprot id: A0A078KD49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

5861:PY17X 1211700
gene id: 5861:PY17X_1211700
uniprot id: A0A078KA59
names: Similarity
messages: Belongs to the proteasome inhibitor PI31 family.

5861:PY17X 1117700
gene id: 5861:PY17X_1117700
uniprot id: A0A078KC27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

5861:PY17X 0816100
gene id: 5861:PY17X_0816100
uniprot id: A0A077Y3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

5861:PY17X 1361600
gene id: 5861:PY17X_1361600
uniprot id: A0A077Y9T8
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

5861:PY17X 1118600
gene id: 5861:PY17X_1118600
uniprot id: A0A077Y7V5
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

5861:PY17X 0503200
gene id: 5861:PY17X_0503200
uniprot id: A0A077Y1A9
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

5861:PY17X 0708900
gene id: 5861:PY17X_0708900
uniprot id: A0A077Y2Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

5861:PY17X 0907800
gene id: 5861:PY17X_0907800
uniprot id: A0A077Y6G1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

5861:PY17X 0110700
gene id: 5861:PY17X_0110700
uniprot id: A0A078K5N6
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

5861:PY17X 0614100
gene id: 5861:PY17X_0614100
uniprot id: A0A077Y1M2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

5861:PY17X 1330100
gene id: 5861:PY17X_1330100
uniprot id: A0A077Y8Z0
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 heme c group covalently per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

5861:PY17X 1357000
gene id: 5861:PY17X_1357000
uniprot id: A0A077YAI6
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

5861:PY17X 1219800
gene id: 5861:PY17X_1219800
uniprot id: A0A078KDW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

5861:PY17X 0930500
gene id: 5861:PY17X_0930500
uniprot id: A0A077Y552
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

5861:PY17X 1411700
gene id: 5861:PY17X_1411700
uniprot id: A0A077YAB1
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

5861:PY17X 1032900
gene id: 5861:PY17X_1032900
uniprot id: A0A078KFF2
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 1104200
gene id: 5861:PY17X_1104200
uniprot id: A0A078K8L4
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

5861:PY17X 1422300
gene id: 5861:PY17X_1422300
uniprot id: A0A077YCV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

5861:PY17X 1143700
gene id: 5861:PY17X_1143700
uniprot id: A0A077YAS2
names: Similarity
messages: Belongs to the NDK family.

5861:PY17X 0607100
gene id: 5861:PY17X_0607100
uniprot id: A0A077Y5P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO4 family.
messages: Membrane

5861:PY17X 0717800
gene id: 5861:PY17X_0717800
uniprot id: A0A078K8X1
names: Similarity
messages: Belongs to the adenylate kinase family.

5861:PY17X 0945800
gene id: 5861:PY17X_0945800
uniprot id: A0A077Y9F7
names: Similarity
messages: Belongs to the actin family.

5861:PY17X 0504700
gene id: 5861:PY17X_0504700
uniprot id: A0A077Y1U9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

5861:PY17X 1128000
gene id: 5861:PY17X_1128000
uniprot id: A0A078KCN3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

5861:PY17X 1204800
gene id: 5861:PY17X_1204800
uniprot id: A0A077Y8W2
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

5861:PY17X 0409500
gene id: 5861:PY17X_0409500
uniprot id: A0A078K4H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

5861:PY17X 0812200
gene id: 5861:PY17X_0812200
uniprot id: A0A077Y5A2
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

5861:PY17X 1464000
gene id: 5861:PY17X_1464000
uniprot id: A0A078KCR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

5861:PY17X 1305700
gene id: 5861:PY17X_1305700
uniprot id: A0A077Y976
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

5861:PY17X 0938600
gene id: 5861:PY17X_0938600
uniprot id: A0A078KBH8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

5861:PY17X 1334200
gene id: 5861:PY17X_1334200
uniprot id: A0A078KKW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. BSU subfamily.
messages: Nucleus

5861:PY17X 1462300
gene id: 5861:PY17X_1462300
uniprot id: A0A4V0KV69
names: Similarity
messages: Belongs to the CWC26 family.

5861:PY17X 0904700
gene id: 5861:PY17X_0904700
uniprot id: A0A078K7E3
names: Similarity
messages: Belongs to the methyltransferase superfamily.

5861:PY17X 0818500
gene id: 5861:PY17X_0818500
uniprot id: A0A077Y496
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

5861:PY17X 0313800
gene id: 5861:PY17X_0313800
uniprot id: A0A078K6U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Membrane

5861:PY17X 0835900
gene id: 5861:PY17X_0835900
uniprot id: A0A077Y7Z0
names: Similarity
messages: Belongs to the PIH1 family.

5861:PY17X 0917100
gene id: 5861:PY17X_0917100
uniprot id: A0A078K4H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

5861:PY17X 1348000
gene id: 5861:PY17X_1348000
uniprot id: A0A077YAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

5861:PY17X 0607800
gene id: 5861:PY17X_0607800
uniprot id: A0A078KD20
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

5861:PY17X 1344600
gene id: 5861:PY17X_1344600
uniprot id: A0A078KHA0
names: Similarity
messages: Belongs to the synaptobrevin family.

5861:PY17X 0925600
gene id: 5861:PY17X_0925600
uniprot id: A0A077Y6Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

5861:PY17X 1359300
gene id: 5861:PY17X_1359300
uniprot id: A0A078KHL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Nucleus
messages: spindle

5861:PY17X 0607600
gene id: 5861:PY17X_0607600
uniprot id: A0A4V0KI07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

5861:PY17X 0617900
gene id: 5861:PY17X_0617900
uniprot id: A0A4V0KIA2
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.

5861:PY17X 1011400
gene id: 5861:PY17X_1011400
uniprot id: A0A078KF77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

5861:PY17X 0214600
gene id: 5861:PY17X_0214600
uniprot id: A0A077Y0J6
names: Similarity
messages: Belongs to the allantoicase family.

5861:PY17X 0506200
gene id: 5861:PY17X_0506200
uniprot id: A0A078K1T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

5861:PY17X 1217100
gene id: 5861:PY17X_1217100
uniprot id: A0A078KA84
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

5861:PY17X 1033000
gene id: 5861:PY17X_1033000
uniprot id: A0A078KJG0
names: Similarity
messages: Belongs to the nuclease type I family.

5861:PY17X 0304200
gene id: 5861:PY17X_0304200
uniprot id: A0A078K3X3
names: Similarity
messages: Belongs to the proteasome subunit S2 family.

5861:PY17X 1361200
gene id: 5861:PY17X_1361200
uniprot id: A0A078KLM3
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Tetramer of two alpha and two beta subunits.

5861:PY17X 0315900
gene id: 5861:PY17X_0315900
uniprot id: A0A077Y107
names: Similarity
messages: Belongs to the SNW family.

5861:PY17X 1219300
gene id: 5861:PY17X_1219300
uniprot id: A0A078KDV8
names: Similarity
messages: Belongs to the CDC123 family.

5861:PY17X 1144800
gene id: 5861:PY17X_1144800
uniprot id: A0A077Y7R4
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

5861:PY17X 1122500
gene id: 5861:PY17X_1122500
uniprot id: A0A077Y632
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

5861:PY17X 1451400
gene id: 5861:PY17X_1451400
uniprot id: A0A077YFH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus

5861:PY17X 1230500
gene id: 5861:PY17X_1230500
uniprot id: A0A077Y7P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF-assemblin family.
messages: cytoskeleton

5861:PY17X 1235200
gene id: 5861:PY17X_1235200
uniprot id: A0A078KDY5
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

5861:PY17X 0915300
gene id: 5861:PY17X_0915300
uniprot id: A0A077Y4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: apicoplast

5861:PY17X 0810200
gene id: 5861:PY17X_0810200
uniprot id: A0A4V6MAH0
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

5861:PY17X 1348600
gene id: 5861:PY17X_1348600
uniprot id: A0A078KHB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.

5861:PY17X 0934200
gene id: 5861:PY17X_0934200
uniprot id: A0A078KB05
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

5861:PY17X 1359700
gene id: 5861:PY17X_1359700
uniprot id: A0A078KHK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

5861:PY17X 1357100
gene id: 5861:PY17X_1357100
uniprot id: A0A078KHK1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

5861:PY17X 1437200
gene id: 5861:PY17X_1437200
uniprot id: A0A077YC22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

5861:PY17X 0203700
gene id: 5861:PY17X_0203700
uniprot id: A0A077XZL6
names: Similarity
messages: Belongs to the adenylate kinase family.

5861:PY17X 0829800
gene id: 5861:PY17X_0829800
uniprot id: A0A078K9M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

5861:PY17X 1406600
gene id: 5861:PY17X_1406600
uniprot id: A0A077YA65
names: Similarity
messages: Belongs to the AAA ATPase family.

5861:PY17X 0720600
gene id: 5861:PY17X_0720600
uniprot id: A0A077Y6R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

5861:PY17X 1364800
gene id: 5861:PY17X_1364800
uniprot id: A0A077YAB7
names: Similarity
messages: Belongs to the MOG1 family.

5861:PY17X 0817100
gene id: 5861:PY17X_0817100
uniprot id: A0A078K6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRM6/GCD10 family.
messages: Nucleus

5861:PY17X 1453800
gene id: 5861:PY17X_1453800
uniprot id: A0A078KCU3
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

5861:PY17X 0313600
gene id: 5861:PY17X_0313600
uniprot id: A0A078K3L1
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

5861:PY17X 1015300
gene id: 5861:PY17X_1015300
uniprot id: A0A078KC85
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 2 family.

5861:PY17X 1020000
gene id: 5861:PY17X_1020000
uniprot id: A0A077YJ94
names: Similarity
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Part of the nascent polypeptide-associated complex (NAC).

5861:PY17X 1456500
gene id: 5861:PY17X_1456500
uniprot id: A0A077YCK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
messages: Homodimer.

5861:PY17X 1452300
gene id: 5861:PY17X_1452300
uniprot id: A0A077YC60
names: Subcellular Location Annotation
messages: Membrane

5861:PY17X 0920500
gene id: 5861:PY17X_0920500
uniprot id: A0A078K7U4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

5861:PY17X 0813900
gene id: 5861:PY17X_0813900
uniprot id: A0A078K379
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.

5861:PY17X 1433200
gene id: 5861:PY17X_1433200
uniprot id: A0A077YB27
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

5861:PY17X 1132500
gene id: 5861:PY17X_1132500
uniprot id: A0A077Y6D7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Parasitic protozoa lack the de novo purine biosynthesis pathway and rely exclusively on the salvage pathway for their purine nucleotide requirements.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.
messages: Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

5861:PY17X 0621500
gene id: 5861:PY17X_0621500
uniprot id: A0A078KDV9
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

5861:PY17X 0707000
gene id: 5861:PY17X_0707000
uniprot id: A0A077Y4J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

5861:PY17X 0614500
gene id: 5861:PY17X_0614500
uniprot id: A0A078KH45
names: Similarity
messages: Belongs to the peptidase S14 family.

5861:PY17X 0811700
gene id: 5861:PY17X_0811700
uniprot id: A0A077Y597
names: Similarity
messages: Belongs to the TBCB family.

5861:PY17X 0826700
gene id: 5861:PY17X_0826700
uniprot id: A0A077Y5U0
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

5861:PY17X 1205000
gene id: 5861:PY17X_1205000
uniprot id: A0A077YAY3
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

5861:PY17X 0315700
gene id: 5861:PY17X_0315700
uniprot id: A0A077XZN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

5861:PY17X 1458800
gene id: 5861:PY17X_1458800
uniprot id: A0A077YCC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

5861:PY17X 1360900
gene id: 5861:PY17X_1360900
uniprot id: A0A078KEW6
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

5861:PY17X 0110400
gene id: 5861:PY17X_0110400
uniprot id: A0A078JZQ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

5861:PY17X 1126900
gene id: 5861:PY17X_1126900
uniprot id: A0A077Y840
names: Similarity
messages: Belongs to the MYG1 family.

5861:PY17X 1134900
gene id: 5861:PY17X_1134900
uniprot id: A0A078K9A3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

5861:PY17X 0408800
gene id: 5861:PY17X_0408800
uniprot id: A0A077Y4G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

5861:PY17X 1446600
gene id: 5861:PY17X_1446600
uniprot id: A0A077YDG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

5861:PY17X 1032500
gene id: 5861:PY17X_1032500
uniprot id: A0A078KJF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Cytoplasm

5861:PY17X 1326200
gene id: 5861:PY17X_1326200
uniprot id: A0A078KKM5
names: Similarity
messages: Belongs to the EXO5 family.

5861:PY17X 0805300
gene id: 5861:PY17X_0805300
uniprot id: A0A078K910
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

5861:PY17X 0701900
gene id: 5861:PY17X_0701900
uniprot id: A0A077Y2U5
names: Similarity
messages: Belongs to the CCDC124 family.

5861:PY17X 0524900
gene id: 5861:PY17X_0524900
uniprot id: A0A077Y2E8
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

5861:PY17X 0837800
gene id: 5861:PY17X_0837800
uniprot id: A0A078KA98
names: Similarity
messages: Belongs to the peptidase M16 family.

5861:PY17X 1023700
gene id: 5861:PY17X_1023700
uniprot id: A0A078KCH9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

5861:PY17X 1109800
gene id: 5861:PY17X_1109800
uniprot id: A0A077Y7N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family.
messages: Nucleus

5861:PY17X 1216300
gene id: 5861:PY17X_1216300
uniprot id: A0A078KDS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

5861:PY17X 1322200
gene id: 5861:PY17X_1322200
uniprot id: A0A078KKJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

5861:PY17X 1130800
gene id: 5861:PY17X_1130800
uniprot id: A0A077Y6C6
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.

5861:PY17X 1309700
gene id: 5861:PY17X_1309700
uniprot id: A0A078KDE8
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

5861:PY17X 0419800
gene id: 5861:PY17X_0419800
uniprot id: A0A077Y4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

5861:PY17X 1463600
gene id: 5861:PY17X_1463600
uniprot id: A0A078KGK2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

5861:PY17X 1118200
gene id: 5861:PY17X_1118200
uniprot id: A0A077Y5Z2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

5861:PY17X 0309700
gene id: 5861:PY17X_0309700
uniprot id: A0A077XZH5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Heterodimer of two subunits, one of which binds GTP.

5861:PY17X 1133400
gene id: 5861:PY17X_1133400
uniprot id: A0A078K991
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

5861:PY17X 1352600
gene id: 5861:PY17X_1352600
uniprot id: A0A077YA25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

5861:PY17X 1013900
gene id: 5861:PY17X_1013900
uniprot id: A0A078KFA2
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

5861:PY17X 0404500
gene id: 5861:PY17X_0404500
uniprot id: A0A078K6P5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

5861:PY17X 1353400
gene id: 5861:PY17X_1353400
uniprot id: A0A078KHH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Nucleus

5861:PY17X 1010400
gene id: 5861:PY17X_1010400
uniprot id: A0A078KF65
names: Similarity
messages: Belongs to the GPI family.

5861:PY17X 0709000
gene id: 5861:PY17X_0709000
uniprot id: A0A078K2K5
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

5861:PY17X 1131800
gene id: 5861:PY17X_1131800
uniprot id: A0A4V0KP29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

5861:PY17X 1234200
gene id: 5861:PY17X_1234200
uniprot id: A0A078KDX7
names: Similarity
messages: Belongs to the pyridoxine kinase family.

5861:PY17X 1448000
gene id: 5861:PY17X_1448000
uniprot id: A0A078KG12
names: Similarity
messages: Belongs to the fl(2)d family.

5861:PY17X 1115400
gene id: 5861:PY17X_1115400
uniprot id: A0A078K8U6
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

5861:PY17X 1441200
gene id: 5861:PY17X_1441200
uniprot id: A0A078K9B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

5861:PY17X 1210400
gene id: 5861:PY17X_1210400
uniprot id: A0A077Y785
names: Similarity
messages: Belongs to the adenylate kinase family.

5861:PY17X 1457700
gene id: 5861:PY17X_1457700
uniprot id: A0A077YDT6
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

5861:PY17X 1216700
gene id: 5861:PY17X_1216700
uniprot id: A0A078KAC6
names: Similarity
messages: Belongs to the CWC16 family.

5861:PY17X 0826400
gene id: 5861:PY17X_0826400
uniprot id: A0A078K3F7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

5861:PY17X 1307500
gene id: 5861:PY17X_1307500
uniprot id: A0A077Y8E3
names: Similarity
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.

5861:PY17X 1110100
gene id: 5861:PY17X_1110100
uniprot id: A0A077Y6M8
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

5861:PY17X 1041800
gene id: 5861:PY17X_1041800
uniprot id: A0A077YJW0
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

5861:PY17X 0303300
gene id: 5861:PY17X_0303300
uniprot id: A0A077Y3Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

5861:PY17X 1011800
gene id: 5861:PY17X_1011800
uniprot id: A0A077YH48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

5861:PY17X 1222700
gene id: 5861:PY17X_1222700
uniprot id: A0A077Y7I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRT-like transporter family.
messages: May regulate endogenous transporter.
messages: Membrane
messages: Vacuole membrane

5861:PY17X 1042300
gene id: 5861:PY17X_1042300
uniprot id: A0A078KD48
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

5861:PY17X 0924100
gene id: 5861:PY17X_0924100
uniprot id: A0A078KB66
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

5861:PY17X 1133500
gene id: 5861:PY17X_1133500
uniprot id: A0A078K9E6
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0104100
gene id: 5861:PY17X_0104100
uniprot id: A0A077XZQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

5861:PY17X 0919400
gene id: 5861:PY17X_0919400
uniprot id: A0A077Y6R5
names: Similarity
messages: Belongs to the AAA ATPase family.

5861:PY17X 0838600
gene id: 5861:PY17X_0838600
uniprot id: A0A077Y4W0
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0603700
gene id: 5861:PY17X_0603700
uniprot id: A0A077Y1B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

5861:PY17X 1035600
gene id: 5861:PY17X_1035600
uniprot id: A0A077YHS8
names: Similarity
messages: Belongs to the DDI1 family.

5861:PY17X 1415100
gene id: 5861:PY17X_1415100
uniprot id: A0A077YBE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

5861:PY17X 1447800
gene id: 5861:PY17X_1447800
uniprot id: A0A078KCP1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

5861:PY17X 0107600
gene id: 5861:PY17X_0107600
uniprot id: A0A077XZT1
names: Similarity
messages: Belongs to the UbiA prenyltransferase family.

5861:PY17X 0919700
gene id: 5861:PY17X_0919700
uniprot id: A0A077Y4L4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

5861:PY17X 0521700
gene id: 5861:PY17X_0521700
uniprot id: A0A078K263
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

5861:PY17X 0416100
gene id: 5861:PY17X_0416100
uniprot id: A0A078K1F8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

5861:PY17X 0941200
gene id: 5861:PY17X_0941200
uniprot id: A0A077Y5B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

5861:PY17X 1307800
gene id: 5861:PY17X_1307800
uniprot id: A0A077YC68
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0521300
gene id: 5861:PY17X_0521300
uniprot id: A0A077Y3F4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

5861:PY17X 0913200
gene id: 5861:PY17X_0913200
uniprot id: A0A078K7C2
names: Similarity
messages: Belongs to the peptidase S8 family.

5861:PY17X 0214800
gene id: 5861:PY17X_0214800
uniprot id: A0A078K5Z3
names: Similarity
messages: Belongs to the NMD3 family.

5861:PY17X 0606800
gene id: 5861:PY17X_0606800
uniprot id: A0A077Y256
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

5861:PY17X 1326700
gene id: 5861:PY17X_1326700
uniprot id: A0A078KKN1
names: Similarity
messages: Belongs to the OPA3 family.

5861:PY17X 1431600
gene id: 5861:PY17X_1431600
uniprot id: A0A078KBW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

5861:PY17X 1308200
gene id: 5861:PY17X_1308200
uniprot id: A0A078KDD7
names: Similarity
messages: Belongs to the allantoicase family.

5861:PY17X 0933500
gene id: 5861:PY17X_0933500
uniprot id: A0A077Y581
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

5861:PY17X 0212900
gene id: 5861:PY17X_0212900
uniprot id: A0A077XZ30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

5861:PY17X 1306200
gene id: 5861:PY17X_1306200
uniprot id: A0A078KDC1
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 1040400
gene id: 5861:PY17X_1040400
uniprot id: A0A077YGK0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

5861:PY17X 0417700
gene id: 5861:PY17X_0417700
uniprot id: A0A077Y0B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

5861:PY17X 0518500
gene id: 5861:PY17X_0518500
uniprot id: A0A078K898
names: Similarity
messages: Belongs to the CEF1 family.

5861:PY17X 1412100
gene id: 5861:PY17X_1412100
uniprot id: A0A077YBB4
names: Similarity
messages: Belongs to the peptidase M1 family.

5861:PY17X 0607300
gene id: 5861:PY17X_0607300
uniprot id: A0A077Y260
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

5861:PY17X 1423400
gene id: 5861:PY17X_1423400
uniprot id: A0A078KBZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

5861:PY17X 1116600
gene id: 5861:PY17X_1116600
uniprot id: A0A077Y7T9
names: Similarity
messages: Belongs to the BolA/IbaG family.

5861:PY17X 0316700
gene id: 5861:PY17X_0316700
uniprot id: A0A078K6F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

5861:PY17X 1236600
gene id: 5861:PY17X_1236600
uniprot id: A0A077Y7V6
names: Similarity
messages: Belongs to the cyclin family.

5861:PY17X 1365400
gene id: 5861:PY17X_1365400
uniprot id: A0A077YDP3
names: Subcellular Location Annotation
messages: Cell surface

5861:PY17X 0912600
gene id: 5861:PY17X_0912600
uniprot id: A0A077Y580
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

5861:PY17X 0828000
gene id: 5861:PY17X_0828000
uniprot id: A0A077Y4K8
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

5861:PY17X 1353900
gene id: 5861:PY17X_1353900
uniprot id: A0A077Y9N9
names: Similarity
messages: Belongs to the AHA1 family.

5861:PY17X 1437300
gene id: 5861:PY17X_1437300
uniprot id: A0A077YB69
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

5861:PY17X 0935000
gene id: 5861:PY17X_0935000
uniprot id: A0A077Y599
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.

5861:PY17X 1213900
gene id: 5861:PY17X_1213900
uniprot id: A0A077Y7C1
names: Similarity
messages: Belongs to the UQCRB/QCR7 family.

5861:PY17X 0315000
gene id: 5861:PY17X_0315000
uniprot id: A0A077Y0J2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

5861:PY17X 1235600
gene id: 5861:PY17X_1235600
uniprot id: A0A077Y7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

5861:PY17X 1364300
gene id: 5861:PY17X_1364300
uniprot id: A0A077YAB3
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

5861:PY17X 0523200
gene id: 5861:PY17X_0523200
uniprot id: A0A077Y146
names: Similarity
messages: Belongs to the RRF family.

5861:PY17X 0704400
gene id: 5861:PY17X_0704400
uniprot id: A0A4V0KJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

5861:PY17X 0301700
gene id: 5861:PY17X_0301700
uniprot id: A0A078K6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

5861:PY17X 1429400
gene id: 5861:PY17X_1429400
uniprot id: A0A078KC46
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

5861:PY17X 0406300
gene id: 5861:PY17X_0406300
uniprot id: A0A078K4E0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

5861:PY17X 0519100
gene id: 5861:PY17X_0519100
uniprot id: A0A078K7X9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

5861:PY17X 1351600
gene id: 5861:PY17X_1351600
uniprot id: A0A077YDB9
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

5861:PY17X 1016400
gene id: 5861:PY17X_1016400
uniprot id: A0A4V0KLX6
names: Subcellular Location Annotation
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane

5861:PY17X 1108300
gene id: 5861:PY17X_1108300
uniprot id: A0A077Y7M4
names: Similarity
messages: Belongs to the CNOT9 family.

5861:PY17X 1231400
gene id: 5861:PY17X_1231400
uniprot id: A0A078KAL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

5861:PY17X 0917300
gene id: 5861:PY17X_0917300
uniprot id: A0A078K7S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

5861:PY17X 1328800
gene id: 5861:PY17X_1328800
uniprot id: A0A077Y962
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

5861:PY17X 1241000
gene id: 5861:PY17X_1241000
uniprot id: A0A078KB04
names: Subcellular Location Annotation
messages: Membrane

5861:PY17X 1324700
gene id: 5861:PY17X_1324700
uniprot id: A0A078KKL2
names: Similarity
messages: Belongs to the thioredoxin family.

5861:PY17X 0941100
gene id: 5861:PY17X_0941100
uniprot id: A0A077Y7B4
names: Similarity
messages: Belongs to the protein kinase superfamily.

5861:PY17X 1135900
gene id: 5861:PY17X_1135900
uniprot id: A0A078K9B3
names: Similarity
messages: Belongs to the SAS10 family.

5861:PY17X 1409200
gene id: 5861:PY17X_1409200
uniprot id: A0A078KEU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: nuclear pore complex

5861:PY17X 1352400
gene id: 5861:PY17X_1352400
uniprot id: A0A078KHG4
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

5861:PY17X 1331800
gene id: 5861:PY17X_1331800
uniprot id: A0A077Y9A5
names: Similarity
messages: Belongs to the cyclin family.

5861:PY17X 1219700
gene id: 5861:PY17X_1219700
uniprot id: A0A077Y7F0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

5861:PY17X 0911600
gene id: 5861:PY17X_0911600
uniprot id: A0A078K7A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Enzyme with a broad specificity.
messages: Membrane

5861:PY17X 1356700
gene id: 5861:PY17X_1356700
uniprot id: A0A077YBQ0
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.

5861:PY17X 0311300
gene id: 5861:PY17X_0311300
uniprot id: A0A078K6S3
names: Similarity
messages: Belongs to the RPAP2 family.

5861:PY17X 0114100
gene id: 5861:PY17X_0114100
uniprot id: A0A078K331
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

5861:PY17X 1422400
gene id: 5861:PY17X_1422400
uniprot id: A0A077YBC6
names: Similarity
messages: Belongs to the CFAP91 family.

5861:PY17X 0705400
gene id: 5861:PY17X_0705400
uniprot id: A0A078K8C5
names: Similarity
messages: Belongs to the KRI1 family.

5861:PY17X 0829300
gene id: 5861:PY17X_0829300
uniprot id: A0A078K9M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Probable methyltransferase required to silence rDNA.
messages: nucleolus

5861:PY17X 0809500
gene id: 5861:PY17X_0809500
uniprot id: A0A078K659
names: Subcellular Location Annotation
messages: Membrane

5861:PY17X 1138900
gene id: 5861:PY17X_1138900
uniprot id: A0A077Y6M0
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

5861:PY17X 0516300
gene id: 5861:PY17X_0516300
uniprot id: A0A078K4Y7
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0822500
gene id: 5861:PY17X_0822500
uniprot id: A0A078K6F2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.

5861:PY17X 0838300
gene id: 5861:PY17X_0838300
uniprot id: A0A078KAA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

5861:PY17X 1015900
gene id: 5861:PY17X_1015900
uniprot id: A0A077YFL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: cytosol

5861:PY17X 1226300
gene id: 5861:PY17X_1226300
uniprot id: A0A077Y9E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus

5861:PY17X 0412900
gene id: 5861:PY17X_0412900
uniprot id: A0A078K1C8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

5861:PY17X 1362700
gene id: 5861:PY17X_1362700
uniprot id: A0A077YBU7
names: Similarity
messages: Belongs to the GcvT family.

5861:PY17X 0304900
gene id: 5861:PY17X_0304900
uniprot id: Q8WSK0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

5861:PY17X 0407900
gene id: 5861:PY17X_0407900
uniprot id: A0A077Y1A6
names: Similarity
messages: Belongs to the MAPRE family.

5861:PY17X 1304100
gene id: 5861:PY17X_1304100
uniprot id: A0A077YC36
names: Similarity
messages: Belongs to the tubulin family.

5861:PY17X 1034700
gene id: 5861:PY17X_1034700
uniprot id: A0A077YG46
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

5861:PY17X 0814000
gene id: 5861:PY17X_0814000
uniprot id: A0A078K688
names: Similarity
messages: Belongs to the FAM154 family.

5861:PY17X 1115800
gene id: 5861:PY17X_1115800
uniprot id: A0A077Y9Y0
names: Similarity
messages: Belongs to the RRM CWC2 family.

5861:PY17X 0912000
gene id: 5861:PY17X_0912000
uniprot id: A0A078K4D4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of the MOCS3/UBA4 homolog, then thiocarboxylated (-COSH) via the rhodanese domain of the MOCS3/UBA4 homolog.
messages: Cytoplasm

5861:PY17X 1313800
gene id: 5861:PY17X_1313800
uniprot id: A0A077Y8R6
names: Similarity
messages: Belongs to the peptidase M17 family.

5861:PY17X 1366700
gene id: 5861:PY17X_1366700
uniprot id: A0A078KLS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

5861:PY17X 1030800
gene id: 5861:PY17X_1030800
uniprot id: A0A078KFN0
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

5861:PY17X 0413300
gene id: 5861:PY17X_0413300
uniprot id: A0A078K4K5
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

5861:PY17X 1131500
gene id: 5861:PY17X_1131500
uniprot id: A0A077Y6C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB4 family.
messages: Nucleus

5861:PY17X 1143800
gene id: 5861:PY17X_1143800
uniprot id: A0A077Y7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

5861:PY17X 0517400
gene id: 5861:PY17X_0517400
uniprot id: A0A078K5D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

5861:PY17X 1456800
gene id: 5861:PY17X_1456800
uniprot id: A0A078KCX9
names: Similarity
messages: Belongs to the VPS16 family.

5861:PY17X 0810800
gene id: 5861:PY17X_0810800
uniprot id: A0A4V0KI79
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

5861:PY17X 1417200
gene id: 5861:PY17X_1417200
uniprot id: A0A077YAI0
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0513600
gene id: 5861:PY17X_0513600
uniprot id: A0A077Y588
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

5861:PY17X 0803600
gene id: 5861:PY17X_0803600
uniprot id: A0A078K6C1
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 1419000
gene id: 5861:PY17X_1419000
uniprot id: A0A078K8S4
names: Subcellular Location Annotation
messages: Membrane

5861:PY17X 0515100
gene id: 5861:PY17X_0515100
uniprot id: A0A077Y5A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus

5861:PY17X 1429800
gene id: 5861:PY17X_1429800
uniprot id: A0A077YBJ8
names: Similarity
messages: Belongs to the RuvB family.

5861:PY17X 1231500
gene id: 5861:PY17X_1231500
uniprot id: Q86SB3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

5861:PY17X 1103100
gene id: 5861:PY17X_1103100
uniprot id: A0A078K8E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

5861:PY17X 1112500
gene id: 5861:PY17X_1112500
uniprot id: A0A077Y7Q9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

5861:PY17X 0621800
gene id: 5861:PY17X_0621800
uniprot id: A0A078KH35
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

5861:PY17X 1219400
gene id: 5861:PY17X_1219400
uniprot id: A0A077Y7H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

5861:PY17X 1219600
gene id: 5861:PY17X_1219600
uniprot id: A0A078KAA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal TPase family.
messages: Nucleus

5861:PY17X 1309100
gene id: 5861:PY17X_1309100
uniprot id: A0A077YAD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

5861:PY17X 1435600
gene id: 5861:PY17X_1435600
uniprot id: A0A077YF20
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

5861:PY17X 1039400
gene id: 5861:PY17X_1039400
uniprot id: A0A077YGJ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

5861:PY17X 1215800
gene id: 5861:PY17X_1215800
uniprot id: A0A077Y948
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAP2/GCS1 family.
messages: Cell membrane
messages: Membrane

5861:PY17X 1215500
gene id: 5861:PY17X_1215500
uniprot id: A0A078K795
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

5861:PY17X 0512000
gene id: 5861:PY17X_0512000
uniprot id: A0A077Y0T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

5861:PY17X 0939100
gene id: 5861:PY17X_0939100
uniprot id: A0A077Y7A5
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

5861:PY17X 0710300
gene id: 5861:PY17X_0710300
uniprot id: A0A078K8Q3
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

5861:PY17X 1317600
gene id: 5861:PY17X_1317600
uniprot id: A0A078KKE1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.
messages: The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.

5861:PY17X 1229000
gene id: 5861:PY17X_1229000
uniprot id: A0A077YBF9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

5861:PY17X 1106900
gene id: 5861:PY17X_1106900
uniprot id: A0A078KBM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

5861:PY17X 1433000
gene id: 5861:PY17X_1433000
uniprot id: A0A077YEZ8
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

5861:PY17X 1360700
gene id: 5861:PY17X_1360700
uniprot id: A0A078KLL9
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

5861:PY17X 0213700
gene id: 5861:PY17X_0213700
uniprot id: A0A078K6F0
names: Similarity
messages: Belongs to the actin family.

5861:PY17X 1353000
gene id: 5861:PY17X_1353000
uniprot id: A0A077YBM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

5861:PY17X 0915900
gene id: 5861:PY17X_0915900
uniprot id: A0A078KAZ3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

5861:PY17X 1343400
gene id: 5861:PY17X_1343400
uniprot id: A0A078KEH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane

5861:PY17X 0523000
gene id: 5861:PY17X_0523000
uniprot id: A0A078K274
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

5861:PY17X 1014800
gene id: 5861:PY17X_1014800
uniprot id: A0A078KC76
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

5861:PY17X 1409800
gene id: 5861:PY17X_1409800
uniprot id: A0A077YCG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

5861:PY17X 1247000
gene id: 5861:PY17X_1247000
uniprot id: A0A077Y8E2
names: Similarity
messages: Belongs to the TIP family.

5861:PY17X 1235900
gene id: 5861:PY17X_1235900
uniprot id: A0A077YBM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

5861:PY17X 1403200
gene id: 5861:PY17X_1403200
uniprot id: A0A078KEH2
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

5861:PY17X 1135000
gene id: 5861:PY17X_1135000
uniprot id: A0A077Y8E7
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

5861:PY17X 0416700
gene id: 5861:PY17X_0416700
uniprot id: A0A077Y096
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

5861:PY17X 0417600
gene id: 5861:PY17X_0417600
uniprot id: A0A4V0KG76
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

5861:PY17X 1210500
gene id: 5861:PY17X_1210500
uniprot id: A0A077YB25
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

5861:PY17X 1036300
gene id: 5861:PY17X_1036300
uniprot id: A0A077YJP9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

5861:PY17X 1441800
gene id: 5861:PY17X_1441800
uniprot id: A0A077YF84
names: Subcellular Location Annotation
messages: nucleolus

5861:PY17X 0812600
gene id: 5861:PY17X_0812600
uniprot id: A0A078K6I0
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins.

5861:PY17X 1410300
gene id: 5861:PY17X_1410300
uniprot id: A0A077YCG6
names: Similarity
messages: Belongs to the ATPase delta chain family.

5861:PY17X 0107100
gene id: 5861:PY17X_0107100
uniprot id: A0A4V0KG23
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.

5861:PY17X 0103400
gene id: 5861:PY17X_0103400
uniprot id: A0A078JZI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Cytoplasm
messages: Nucleus

5861:PY17X 1014700
gene id: 5861:PY17X_1014700
uniprot id: A0A078KIL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

5861:PY17X 1461900
gene id: 5861:PY17X_1461900
uniprot id: A0A078KD38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Cytoplasm

5861:PY17X 0103900
gene id: 5861:PY17X_0103900
uniprot id: A0A077XY56
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

5861:PY17X 0608600
gene id: 5861:PY17X_0608600
uniprot id: A0A077Y5R0
names: Similarity
messages: Belongs to the IPP transferase family.

5861:PY17X 0605700
gene id: 5861:PY17X_0605700
uniprot id: A0A078KDG7
names: Function
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

5861:PY17X 1247400
gene id: 5861:PY17X_1247400
uniprot id: A0A077YA76
names: Subcellular Location Annotation
messages: Cytoplasm

5861:PY17X 1426900
gene id: 5861:PY17X_1426900
uniprot id: A0A078KC21
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

5861:PY17X 0823100
gene id: 5861:PY17X_0823100
uniprot id: A0A077Y3S4
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

5861:PY17X 1448700
gene id: 5861:PY17X_1448700
uniprot id: A0A077YC24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus

5861:PY17X 1444400
gene id: 5861:PY17X_1444400
uniprot id: A0A078KC70
names: Similarity
messages: Belongs to the DEAD box helicase family.

5861:PY17X 1032200
gene id: 5861:PY17X_1032200
uniprot id: A0A078KCS4
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

5861:PY17X 1324300
gene id: 5861:PY17X_1324300
uniprot id: A0A078KKA6
names: Subcellular Location Annotation
messages: Membrane

5861:PY17X 1448100
gene id: 5861:PY17X_1448100
uniprot id: A0A077YDI0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

5861:PY17X 1242000
gene id: 5861:PY17X_1242000
uniprot id: A0A078KB13
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

5861:PY17X 0519600
gene id: 5861:PY17X_0519600
uniprot id: A0A077Y2A5
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

5861:PY17X 0304500
gene id: 5861:PY17X_0304500
uniprot id: A0A078K0J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

5861:PY17X 1121500
gene id: 5861:PY17X_1121500
uniprot id: A0A078K5W4
names: Similarity
messages: Belongs to the PdxS/SNZ family.

5861:PY17X 1340800
gene id: 5861:PY17X_1340800
uniprot id: A0A078KKU7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.

5861:PY17X 1217200
gene id: 5861:PY17X_1217200
uniprot id: A0A4V0KR08
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

5861:PY17X 1224000
gene id: 5861:PY17X_1224000
uniprot id: A0A4V0KQF8
names: Subcellular Location Annotation
messages: centrosome

5861:PY17X 0417400
gene id: 5861:PY17X_0417400
uniprot id: A0A078K7F6
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

5861:PY17X 0212700
gene id: 5861:PY17X_0212700
uniprot id: A0A078K6D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Cytoplasm

5861:PY17X 1350400
gene id: 5861:PY17X_1350400
uniprot id: A0A078KL20
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

5861:PY17X 0712100
gene id: 5861:PY17X_0712100
uniprot id: A0A078K5J1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

5861:PY17X 1003800
gene id: 5861:PY17X_1003800
uniprot id: A0A077YIL7
names: Similarity
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

5861:PY17X 0911000
gene id: 5861:PY17X_0911000
uniprot id: A0A078K4A4
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0523100
gene id: 5861:PY17X_0523100
uniprot id: A0A078K532
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 1004000
gene id: 5861:PY17X_1004000
uniprot id: A0A078KIC2
names: Subcellular Location Annotation
messages: Cell surface

5861:PY17X 1304500
gene id: 5861:PY17X_1304500
uniprot id: A0A078KDB0
names: Function
names: Subcellular Location Annotation
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
messages: Mitochondrion inner membrane

5861:PY17X 1111700
gene id: 5861:PY17X_1111700
uniprot id: A0A078K5K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTP family.
messages: Cytoplasm

5861:PY17X 1335900
gene id: 5861:PY17X_1335900
uniprot id: A0A077YCU2
names: Subcellular Location Annotation
messages: Membrane

5861:PY17X 1134100
gene id: 5861:PY17X_1134100
uniprot id: A0A077Y6F8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

5861:PY17X 0945700
gene id: 5861:PY17X_0945700
uniprot id: A0A077Y5E0
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Tetramer of two alpha and two beta subunits.

5861:PY17X 1407300
gene id: 5861:PY17X_1407300
uniprot id: A0A078KEL3
names: Subcellular Location Annotation
messages: nucleolus

5861:PY17X 1338800
gene id: 5861:PY17X_1338800
uniprot id: A0A078KKS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

5861:PY17X 1125900
gene id: 5861:PY17X_1125900
uniprot id: A0A078KCM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

5861:PY17X 1323500
gene id: 5861:PY17X_1323500
uniprot id: A0A078KGG1
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0314300
gene id: 5861:PY17X_0314300
uniprot id: A0A078K6U6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

5861:PY17X 1125300
gene id: 5861:PY17X_1125300
uniprot id: A0A077Y675
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

5861:PY17X 1430800
gene id: 5861:PY17X_1430800
uniprot id: A0A077YBK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

5861:PY17X 0420500
gene id: 5861:PY17X_0420500
uniprot id: A0A4V0KG74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

5861:PY17X 1425600
gene id: 5861:PY17X_1425600
uniprot id: A0A077YCZ1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

5861:PY17X 1450200
gene id: 5861:PY17X_1450200
uniprot id: A0A4V0KU58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

5861:PY17X 0834400
gene id: 5861:PY17X_0834400
uniprot id: A0A077Y7Y3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

5861:PY17X 1309400
gene id: 5861:PY17X_1309400
uniprot id: A0A077Y995
names: Similarity
messages: Belongs to the peptidase M76 family.

5861:PY17X 1307100
gene id: 5861:PY17X_1307100
uniprot id: A0A078KJT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Membrane

5861:PY17X 0913600
gene id: 5861:PY17X_0913600
uniprot id: A0A078K4E7
names: Similarity
messages: Belongs to the protein kinase superfamily.

5861:PY17X 0839000
gene id: 5861:PY17X_0839000
uniprot id: Q26217
names: Similarity
messages: Belongs to the protein kinase superfamily.

5861:PY17X 0214700
gene id: 5861:PY17X_0214700
uniprot id: A0A077Y041
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

5861:PY17X 0710800
gene id: 5861:PY17X_0710800
uniprot id: A0A077Y3G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

5861:PY17X 1230100
gene id: 5861:PY17X_1230100
uniprot id: A0A077Y9I2
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.

5861:PY17X 1022500
gene id: 5861:PY17X_1022500
uniprot id: A0A077YF31
names: Similarity
messages: Belongs to the actin family.

5861:PY17X 0818900
gene id: 5861:PY17X_0818900
uniprot id: A0A078K3A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

5861:PY17X 0719300
gene id: 5861:PY17X_0719300
uniprot id: A0A077Y352
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the thymidylate synthase family.
messages: In the N-terminal section; belongs to the dihydrofolate reductase family.

5861:PY17X 1017200
gene id: 5861:PY17X_1017200
uniprot id: A0A077YEV0
names: Similarity
messages: Belongs to the archease family.

5861:PY17X 1350200
gene id: 5861:PY17X_1350200
uniprot id: A0A078KHF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

5861:PY17X 1332800
gene id: 5861:PY17X_1332800
uniprot id: A0A078KKK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

5861:PY17X 0616300
gene id: 5861:PY17X_0616300
uniprot id: A0A077Y1P6
names: Similarity
messages: Belongs to the PPC synthetase family.

5861:PY17X 0518000
gene id: 5861:PY17X_0518000
uniprot id: A0A078K892
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.
messages: Belongs to the eukaryotic AdoMetDC family.

5861:PY17X 1349100
gene id: 5861:PY17X_1349100
uniprot id: A0A077YAC9
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0310100
gene id: 5861:PY17X_0310100
uniprot id: A0A078K3H6
names: Similarity
messages: Belongs to the SRR1 family.

5861:PY17X 0302900
gene id: 5861:PY17X_0302900
uniprot id: A0A077Y0P1
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Cytoplasm
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

5861:PY17X 0208000
gene id: 5861:PY17X_0208000
uniprot id: A0A078K2V4
names: Subcellular Location Annotation
messages: nucleolus

5861:PY17X 0403800
gene id: 5861:PY17X_0403800
uniprot id: A0A078K4B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

5861:PY17X 1138500
gene id: 5861:PY17X_1138500
uniprot id: A0A078K9K2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.

5861:PY17X 1334400
gene id: 5861:PY17X_1334400
uniprot id: A0A077YCR8
names: Similarity
messages: Belongs to the proteasome subunit S1 family.

5861:PY17X 0939700
gene id: 5861:PY17X_0939700
uniprot id: A0A078KB61
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

5861:PY17X 1324800
gene id: 5861:PY17X_1324800
uniprot id: A0A077Y908
names: Similarity
messages: Belongs to the PDCD4 family.

5861:PY17X 0935900
gene id: 5861:PY17X_0935900
uniprot id: A0A078K7X1
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

5861:PY17X 1209800
gene id: 5861:PY17X_1209800
uniprot id: A0A078KDF8
names: Similarity
messages: Belongs to the AAA ATPase family.

5861:PY17X 0827200
gene id: 5861:PY17X_0827200
uniprot id: A0A077Y5U5
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

5861:PY17X 1430900
gene id: 5861:PY17X_1430900
uniprot id: A0A077YEY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

5861:PY17X 0315600
gene id: 5861:PY17X_0315600
uniprot id: A0A077Y1V6
names: Similarity
messages: Belongs to the DEAD box helicase family.

5861:PY17X 0609600
gene id: 5861:PY17X_0609600
uniprot id: A0A078KAD5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

5861:PY17X 1237600
gene id: 5861:PY17X_1237600
uniprot id: A0A078KE72
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

5861:PY17X 1368600
gene id: 5861:PY17X_1368600
uniprot id: A0A078KHU6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

5861:PY17X 1460000
gene id: 5861:PY17X_1460000
uniprot id: A0A077YCP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

5861:PY17X 1423300
gene id: 5861:PY17X_1423300
uniprot id: A0A077YEM8
names: Cofactor
messages: Divalent metal ions. Mg(2+) is the most effective.

5861:PY17X 0903000
gene id: 5861:PY17X_0903000
uniprot id: A0A077Y852
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

5861:PY17X 0604700
gene id: 5861:PY17X_0604700
uniprot id: A0A078KDG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

5861:PY17X 1352700
gene id: 5861:PY17X_1352700
uniprot id: A0A077YDC9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

5861:PY17X 0519300
gene id: 5861:PY17X_0519300
uniprot id: A0A078K508
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

5861:PY17X 0214900
gene id: 5861:PY17X_0214900
uniprot id: A0A078K0D5
names: Similarity
messages: Belongs to the BRX1 family.

5861:PY17X 1342900
gene id: 5861:PY17X_1342900
uniprot id: A0A077YCZ9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

5861:PY17X 0932200
gene id: 5861:PY17X_0932200
uniprot id: A0A078KAY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

5861:PY17X 1335400
gene id: 5861:PY17X_1335400
uniprot id: A0A077YCT8
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

5861:PY17X 1365300
gene id: 5861:PY17X_1365300
uniprot id: A0A078KLC0
names: Subcellular Location Annotation
messages: Cell surface

5861:PY17X 0522100
gene id: 5861:PY17X_0522100
uniprot id: A0A078K813
names: Similarity
messages: Belongs to the Rab GDI family.

5861:PY17X 1216900
gene id: 5861:PY17X_1216900
uniprot id: A0A078KDI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

5861:PY17X 0523900
gene id: 5861:PY17X_0523900
uniprot id: A0A078K830
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

5861:PY17X 1122200
gene id: 5861:PY17X_1122200
uniprot id: A0A077Y6Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Cytoplasm
messages: nucleolus

5861:PY17X 1012100
gene id: 5861:PY17X_1012100
uniprot id: A0A078KIW0
names: Subcellular Location Annotation
messages: Cytoplasm

5861:PY17X 0808500
gene id: 5861:PY17X_0808500
uniprot id: A0A078K6E8
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

5861:PY17X 1439800
gene id: 5861:PY17X_1439800
uniprot id: A0A077YF64
names: Similarity
messages: Belongs to the heat shock protein 90 family.

5861:PY17X 1231700
gene id: 5861:PY17X_1231700
uniprot id: A0A077Y7U1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

5861:PY17X 0831800
gene id: 5861:PY17X_0831800
uniprot id: A0A078K9P9
names: Similarity
messages: Belongs to the PPP phosphatase family.

5861:PY17X 0721300
gene id: 5861:PY17X_0721300
uniprot id: A0A078K914
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: Membrane

5861:PY17X 0620300
gene id: 5861:PY17X_0620300
uniprot id: A0A077Y1T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

5861:PY17X 0717200
gene id: 5861:PY17X_0717200
uniprot id: A0A078K5Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

5861:PY17X 0819700
gene id: 5861:PY17X_0819700
uniprot id: A0A077Y5I5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha (regulatory) and two beta (catalytic) chains.

5861:PY17X 0515600
gene id: 5861:PY17X_0515600
uniprot id: A0A077Y263
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

5861:PY17X 1211600
gene id: 5861:PY17X_1211600
uniprot id: A0A078KA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

5861:PY17X 0213500
gene id: 5861:PY17X_0213500
uniprot id: A0A078K326
names: Similarity
messages: Belongs to the eIF-2-alpha family.

5861:PY17X 0934400
gene id: 5861:PY17X_0934400
uniprot id: A0A078K7V4
names: Similarity
messages: Belongs to the peptidase C1 family.

5861:PY17X 0420300
gene id: 5861:PY17X_0420300
uniprot id: A0A078K4S2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

5861:PY17X 0619800
gene id: 5861:PY17X_0619800
uniprot id: A0A077Y1T4
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

5861:PY17X 1427100
gene id: 5861:PY17X_1427100
uniprot id: A0A077YD03
names: Similarity
messages: Belongs to the importin alpha family.

5861:PY17X 0213000
gene id: 5861:PY17X_0213000
uniprot id: A0A077Y3J2
names: Similarity
messages: Belongs to the mTERF family.

5861:PY17X 1449400
gene id: 5861:PY17X_1449400
uniprot id: A0A077YCD7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

5861:PY17X 1443900
gene id: 5861:PY17X_1443900
uniprot id: A0A078KC66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

5861:PY17X 1461200
gene id: 5861:PY17X_1461200
uniprot id: A0A077YBT4
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

5861:PY17X 0407000
gene id: 5861:PY17X_0407000
uniprot id: A0A078K6T2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

5861:PY17X 0611400
gene id: 5861:PY17X_0611400
uniprot id: A0A078KH12
names: Subcellular Location Annotation
messages: Nucleus

5861:PY17X 0936300
gene id: 5861:PY17X_0936300
uniprot id: A0A077Y928
names: Subcellular Location Annotation
messages: Membrane

5861:PY17X 0717600
gene id: 5861:PY17X_0717600
uniprot id: A0A078K5N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

5861:PY17X 1442900
gene id: 5861:PY17X_1442900
uniprot id: A0A077YC72
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

5861:PY17X 1370100
gene id: 5861:PY17X_1370100
uniprot id: A0A078KHV7
names: Similarity
messages: Belongs to the FGGY kinase family.

5861:PY17X 0809200
gene id: 5861:PY17X_0809200
uniprot id: A0A078K9I3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

5861:PY17X 0507800
gene id: 5861:PY17X_0507800
uniprot id: A0A077Y1J3
names: Similarity
messages: Belongs to the citrate synthase family.

5861:PY17X 1240800
gene id: 5861:PY17X_1240800
uniprot id: A0A078K7U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

5861:PY17X 0902700.1
gene id: 5861:PY17X_0902700.1
uniprot id: A0A4V0KKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apicomplexan parasites AMA1 family.
messages: Membrane

5861:PY17X 0720800
gene id: 5861:PY17X_0720800
uniprot id: A0A078K907
names: Similarity
messages: Belongs to the NOB1 family.

5861:PY17X 1330600
gene id: 5861:PY17X_1330600
uniprot id: A0A077Y8Z6
names: Similarity
messages: Belongs to the activator 1 small subunits family.

5861:PY17X 1032400
gene id: 5861:PY17X_1032400
uniprot id: A0A078KFE7
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

5861:PY17X 1341600
gene id: 5861:PY17X_1341600
uniprot id: A0A077Y9C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

5861:PY17X 1030100
gene id: 5861:PY17X_1030100
uniprot id: A0A077YHP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

5861:PY17X 1322100
gene id: 5861:PY17X_1322100
uniprot id: A0A078KGH2
names: Subcellular Location Annotation
messages: chloroplast

5861:PY17X 1454100
gene id: 5861:PY17X_1454100
uniprot id: A0A078KG59
names: Similarity
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer.

5861:PY17X 0824200
gene id: 5861:PY17X_0824200
uniprot id: A0A078K9Y0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

5861:PY17X 1437500
gene id: 5861:PY17X_1437500
uniprot id: A0A077YBR5
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

5861:PY17X 1016500
gene id: 5861:PY17X_1016500
uniprot id: A0A078KEY8
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

5861:PY17X 1030700
gene id: 5861:PY17X_1030700
uniprot id: A0A077YG13
names: Similarity
messages: Belongs to the PPP phosphatase family.

5861:PY17X 1038500
gene id: 5861:PY17X_1038500
uniprot id: A0A077YFG6
names: Similarity
messages: Belongs to the TUB family.

5861:PY17X 1008200
gene id: 5861:PY17X_1008200
uniprot id: A0A077YFB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

5861:PY17X 0617200
gene id: 5861:PY17X_0617200
uniprot id: A0A077Y423
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

5861:PY17X 0407700
gene id: 5861:PY17X_0407700
uniprot id: A0A077XZZ7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.