583346:CKR RS06610
gene id: 583346:CKR_RS06610
uniprot id: B9E1B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

583346:CKR RS06755
gene id: 583346:CKR_RS06755
uniprot id: B9E1E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

583346:CKR RS15850
gene id: 583346:CKR_RS15850
uniprot id: B9E689
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS03245
gene id: 583346:CKR_RS03245
uniprot id: B9DZG2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

583346:CKR RS06555
gene id: 583346:CKR_RS06555
uniprot id: B9E1A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

583346:CKR RS13090
gene id: 583346:CKR_RS13090
uniprot id: B9E4T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583346:CKR RS18560
gene id: 583346:CKR_RS18560
uniprot id: B9DXQ1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

583346:CKR RS15560
gene id: 583346:CKR_RS15560
uniprot id: B9E636
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

583346:CKR RS07230
gene id: 583346:CKR_RS07230
uniprot id: B9E1N8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

583346:CKR RS11340
gene id: 583346:CKR_RS11340
uniprot id: B9E3V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

583346:CKR RS07920
gene id: 583346:CKR_RS07920
uniprot id: B9E222
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

583346:CKR RS02170
gene id: 583346:CKR_RS02170
uniprot id: B9DYV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

583346:CKR RS03695
gene id: 583346:CKR_RS03695
uniprot id: B9DZP7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

583346:CKR RS14210
gene id: 583346:CKR_RS14210
uniprot id: B9E5E0
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

583346:CKR RS11600
gene id: 583346:CKR_RS11600
uniprot id: B9E408
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

583346:CKR RS14795
gene id: 583346:CKR_RS14795
uniprot id: B9E5Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

583346:CKR RS06970
gene id: 583346:CKR_RS06970
uniprot id: B9E1I5
names: Similarity
messages: Belongs to the DprA/Smf family.

583346:CKR RS17705
gene id: 583346:CKR_RS17705
uniprot id: B9DXA6
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS03450
gene id: 583346:CKR_RS03450
uniprot id: B9DZJ9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

583346:CKR RS11270
gene id: 583346:CKR_RS11270
uniprot id: B9E3U3
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

583346:CKR RS00190
gene id: 583346:CKR_RS00190
uniprot id: B9DXV5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS00965
gene id: 583346:CKR_RS00965
uniprot id: B9DY83
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

583346:CKR RS01245
gene id: 583346:CKR_RS01245
uniprot id: B9DYD7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

583346:CKR RS13125
gene id: 583346:CKR_RS13125
uniprot id: B9E4U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583346:CKR RS10555
gene id: 583346:CKR_RS10555
uniprot id: B9E3F6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583346:CKR RS07015
gene id: 583346:CKR_RS07015
uniprot id: B9E1J4
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

583346:CKR RS08155
gene id: 583346:CKR_RS08155
uniprot id: B9E266
names: Similarity
messages: Belongs to the ArsC family.

583346:CKR RS16140
gene id: 583346:CKR_RS16140
uniprot id: B9DWH7
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS07185
gene id: 583346:CKR_RS07185
uniprot id: B9E1M8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

583346:CKR RS06960
gene id: 583346:CKR_RS06960
uniprot id: B9E1I3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

583346:CKR RS16495
gene id: 583346:CKR_RS16495
uniprot id: B9DWN2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

583346:CKR RS12990
gene id: 583346:CKR_RS12990
uniprot id: B9E4S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

583346:CKR RS04545
gene id: 583346:CKR_RS04545
uniprot id: B9E062
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

583346:CKR RS09905
gene id: 583346:CKR_RS09905
uniprot id: B9E334
names: Similarity
messages: Belongs to the bacterial flagellin family.

583346:CKR RS13205
gene id: 583346:CKR_RS13205
uniprot id: B9E4W2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

583346:CKR RS01975
gene id: 583346:CKR_RS01975
uniprot id: B9DYS5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

583346:CKR RS02525
gene id: 583346:CKR_RS02525
uniprot id: B9DZ27
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

583346:CKR RS03400
gene id: 583346:CKR_RS03400
uniprot id: B9DZI9
names: Similarity
messages: Belongs to the EamA transporter family.

583346:CKR RS08160
gene id: 583346:CKR_RS08160
uniprot id: B9E267
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS18655
gene id: 583346:CKR_RS18655
uniprot id: B9DXS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

583346:CKR RS10375
gene id: 583346:CKR_RS10375
uniprot id: B9E3C5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

583346:CKR RS16185
gene id: 583346:CKR_RS16185
uniprot id: B9DWI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

583346:CKR RS16780
gene id: 583346:CKR_RS16780
uniprot id: B9DWT6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS01025
gene id: 583346:CKR_RS01025
uniprot id: B9DY93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

583346:CKR RS08500
gene id: 583346:CKR_RS08500
uniprot id: B9E2C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

583346:CKR RS08390
gene id: 583346:CKR_RS08390
uniprot id: B9E2B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

583346:CKR RS07485
gene id: 583346:CKR_RS07485
uniprot id: B9E1T5
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS06255
gene id: 583346:CKR_RS06255
uniprot id: B9E141
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583346:CKR RS06060
gene id: 583346:CKR_RS06060
uniprot id: B9E102
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

583346:CKR RS07660
gene id: 583346:CKR_RS07660
uniprot id: B9E1X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

583346:CKR RS09900
gene id: 583346:CKR_RS09900
uniprot id: B9E333
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

583346:CKR RS10480
gene id: 583346:CKR_RS10480
uniprot id: B9E3E4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

583346:CKR RS07520
gene id: 583346:CKR_RS07520
uniprot id: B9E1U2
names: Similarity
messages: Belongs to the thioesterase family.

583346:CKR RS00985
gene id: 583346:CKR_RS00985
uniprot id: B9DY87
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

583346:CKR RS07910
gene id: 583346:CKR_RS07910
uniprot id: B9E220
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS00510
gene id: 583346:CKR_RS00510
uniprot id: B9DY05
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

583346:CKR RS05365
gene id: 583346:CKR_RS05365
uniprot id: B9E0L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS06080
gene id: 583346:CKR_RS06080
uniprot id: B9E106
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

583346:CKR RS07985
gene id: 583346:CKR_RS07985
uniprot id: B9E234
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

583346:CKR RS03445
gene id: 583346:CKR_RS03445
uniprot id: B9DZJ8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

583346:CKR RS14515
gene id: 583346:CKR_RS14515
uniprot id: B9E5J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

583346:CKR RS07620
gene id: 583346:CKR_RS07620
uniprot id: B9E1W4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

583346:CKR RS06435
gene id: 583346:CKR_RS06435
uniprot id: B9E177
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

583346:CKR RS02530
gene id: 583346:CKR_RS02530
uniprot id: B9DZ28
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

583346:CKR RS04840
gene id: 583346:CKR_RS04840
uniprot id: B9E0B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

583346:CKR RS01275
gene id: 583346:CKR_RS01275
uniprot id: B9DYE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

583346:CKR RS08895
gene id: 583346:CKR_RS08895
uniprot id: B9E2K6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

583346:CKR RS06245
gene id: 583346:CKR_RS06245
uniprot id: B9E139
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583346:CKR RS00625
gene id: 583346:CKR_RS00625
uniprot id: B9DY28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS17815
gene id: 583346:CKR_RS17815
uniprot id: B9DXC7
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

583346:CKR RS17085
gene id: 583346:CKR_RS17085
uniprot id: B9DWZ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS05285
gene id: 583346:CKR_RS05285
uniprot id: B9E0K1
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

583346:CKR RS18335
gene id: 583346:CKR_RS18335
uniprot id: B9DXL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

583346:CKR RS00535
gene id: 583346:CKR_RS00535
uniprot id: B9DY10
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

583346:CKR RS04790
gene id: 583346:CKR_RS04790
uniprot id: B9E0A2
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

583346:CKR RS05075
gene id: 583346:CKR_RS05075
uniprot id: B9E0F9
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

583346:CKR RS05775
gene id: 583346:CKR_RS05775
uniprot id: B9E0U6
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

583346:CKR RS18605
gene id: 583346:CKR_RS18605
uniprot id: B9DXR0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

583346:CKR RS00090
gene id: 583346:CKR_RS00090
uniprot id: B9DXT9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

583346:CKR RS14410
gene id: 583346:CKR_RS14410
uniprot id: B9E5H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583346:CKR RS07895
gene id: 583346:CKR_RS07895
uniprot id: B9E217
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

583346:CKR RS15880
gene id: 583346:CKR_RS15880
uniprot id: B9E695
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

583346:CKR RS04810
gene id: 583346:CKR_RS04810
uniprot id: B9E0A6
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

583346:CKR RS05815
gene id: 583346:CKR_RS05815
uniprot id: B9E0V4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

583346:CKR RS00345
gene id: 583346:CKR_RS00345
uniprot id: B9DXY0
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

583346:CKR RS06815
gene id: 583346:CKR_RS06815
uniprot id: B9E1F4
names: Similarity
messages: Belongs to the asp23 family.

583346:CKR RS00720
gene id: 583346:CKR_RS00720
uniprot id: B9DY48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

583346:CKR RS04670
gene id: 583346:CKR_RS04670
uniprot id: B9E087
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

583346:CKR RS02110
gene id: 583346:CKR_RS02110
uniprot id: B9DYU7
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

583346:CKR RS17485
gene id: 583346:CKR_RS17485
uniprot id: B9DX63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

583346:CKR RS12290
gene id: 583346:CKR_RS12290
uniprot id: B9E4E0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS03880
gene id: 583346:CKR_RS03880
uniprot id: B9DZT2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

583346:CKR RS05250
gene id: 583346:CKR_RS05250
uniprot id: B9E0J4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

583346:CKR RS16570
gene id: 583346:CKR_RS16570
uniprot id: B9DWP6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

583346:CKR RS03115
gene id: 583346:CKR_RS03115
uniprot id: B9DZD7
names: Similarity
messages: Belongs to the UPF0251 family.

583346:CKR RS10400
gene id: 583346:CKR_RS10400
uniprot id: B9E3D0
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

583346:CKR RS09530
gene id: 583346:CKR_RS09530
uniprot id: B9E2W1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583346:CKR RS13285
gene id: 583346:CKR_RS13285
uniprot id: B9E4X8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

583346:CKR RS18170
gene id: 583346:CKR_RS18170
uniprot id: B9DXI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

583346:CKR RS00990
gene id: 583346:CKR_RS00990
uniprot id: B9DY88
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

583346:CKR RS00550
gene id: 583346:CKR_RS00550
uniprot id: B9DY13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

583346:CKR RS01115
gene id: 583346:CKR_RS01115
uniprot id: B9DYB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

583346:CKR RS17975
gene id: 583346:CKR_RS17975
uniprot id: B9DXF7
names: Similarity
messages: Belongs to the MotB family.

583346:CKR RS15690
gene id: 583346:CKR_RS15690
uniprot id: B9E657
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

583346:CKR RS16150
gene id: 583346:CKR_RS16150
uniprot id: B9DWH9
names: Similarity
messages: Belongs to the EutP/PduV family.

583346:CKR RS17660
gene id: 583346:CKR_RS17660
uniprot id: B9DX97
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

583346:CKR RS05665
gene id: 583346:CKR_RS05665
uniprot id: B9E0S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

583346:CKR RS03935
gene id: 583346:CKR_RS03935
uniprot id: B9DZU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

583346:CKR RS10000
gene id: 583346:CKR_RS10000
uniprot id: B9E353
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

583346:CKR RS09660
gene id: 583346:CKR_RS09660
uniprot id: B9E2Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583346:CKR RS17160
gene id: 583346:CKR_RS17160
uniprot id: B9DX06
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

583346:CKR RS09490
gene id: 583346:CKR_RS09490
uniprot id: B9E2V2
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS04330
gene id: 583346:CKR_RS04330
uniprot id: B9E020
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

583346:CKR RS11020
gene id: 583346:CKR_RS11020
uniprot id: B9E3P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

583346:CKR RS16655
gene id: 583346:CKR_RS16655
uniprot id: B9DWR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

583346:CKR RS16625
gene id: 583346:CKR_RS16625
uniprot id: B9DWQ7
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS06875
gene id: 583346:CKR_RS06875
uniprot id: B9E1G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

583346:CKR RS01125
gene id: 583346:CKR_RS01125
uniprot id: B9DYB3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

583346:CKR RS17655
gene id: 583346:CKR_RS17655
uniprot id: B9DX96
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

583346:CKR RS17565
gene id: 583346:CKR_RS17565
uniprot id: B9DX79
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS00010
gene id: 583346:CKR_RS00010
uniprot id: B9DXS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

583346:CKR RS11195
gene id: 583346:CKR_RS11195
uniprot id: B9E3S7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

583346:CKR RS02580
gene id: 583346:CKR_RS02580
uniprot id: B9DZ37
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS01260
gene id: 583346:CKR_RS01260
uniprot id: B9DYE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

583346:CKR RS16025
gene id: 583346:CKR_RS16025
uniprot id: B9E6C4
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS06540
gene id: 583346:CKR_RS06540
uniprot id: B9E198
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

583346:CKR RS05700
gene id: 583346:CKR_RS05700
uniprot id: B9E0T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

583346:CKR RS01795
gene id: 583346:CKR_RS01795
uniprot id: B9DYN9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

583346:CKR RS06795
gene id: 583346:CKR_RS06795
uniprot id: B9E1E9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

583346:CKR RS17155
gene id: 583346:CKR_RS17155
uniprot id: B9DX05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

583346:CKR RS17315
gene id: 583346:CKR_RS17315
uniprot id: B9DX34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

583346:CKR RS00155
gene id: 583346:CKR_RS00155
uniprot id: B9DXU9
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

583346:CKR RS06920
gene id: 583346:CKR_RS06920
uniprot id: B9E1H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

583346:CKR RS15860
gene id: 583346:CKR_RS15860
uniprot id: B9E691
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

583346:CKR RS03435
gene id: 583346:CKR_RS03435
uniprot id: B9DZJ6
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

583346:CKR RS10155
gene id: 583346:CKR_RS10155
uniprot id: B9E382
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS00995
gene id: 583346:CKR_RS00995
uniprot id: B9DY89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

583346:CKR RS18015
gene id: 583346:CKR_RS18015
uniprot id: B9DXG5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

583346:CKR RS06445
gene id: 583346:CKR_RS06445
uniprot id: B9E179
names: Similarity
messages: Belongs to the UPF0751 family.

583346:CKR RS11300
gene id: 583346:CKR_RS11300
uniprot id: B9E3U9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

583346:CKR RS06880
gene id: 583346:CKR_RS06880
uniprot id: B9E1G7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

583346:CKR RS07000
gene id: 583346:CKR_RS07000
uniprot id: B9E1J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

583346:CKR RS01085
gene id: 583346:CKR_RS01085
uniprot id: B9DYA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

583346:CKR RS17965
gene id: 583346:CKR_RS17965
uniprot id: B9DXF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

583346:CKR RS01785
gene id: 583346:CKR_RS01785
uniprot id: B9DYN7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS01150
gene id: 583346:CKR_RS01150
uniprot id: B9DYB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

583346:CKR RS15315
gene id: 583346:CKR_RS15315
uniprot id: B9E5Z6
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS04550
gene id: 583346:CKR_RS04550
uniprot id: B9E063
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

583346:CKR RS08830
gene id: 583346:CKR_RS08830
uniprot id: B9E2J3
names: Function
names: Similarity
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.

583346:CKR RS09605
gene id: 583346:CKR_RS09605
uniprot id: B9E2X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

583346:CKR RS11890
gene id: 583346:CKR_RS11890
uniprot id: B9E463
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS14835
gene id: 583346:CKR_RS14835
uniprot id: B9E5Q9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

583346:CKR RS06045
gene id: 583346:CKR_RS06045
uniprot id: B9E0Z9
names: Similarity
messages: Belongs to the asp23 family.

583346:CKR RS04040
gene id: 583346:CKR_RS04040
uniprot id: B9DZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

583346:CKR RS06125
gene id: 583346:CKR_RS06125
uniprot id: B9E115
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

583346:CKR RS07605
gene id: 583346:CKR_RS07605
uniprot id: B9E1W1
names: Similarity
messages: Belongs to the hemerythrin family.

583346:CKR RS04260
gene id: 583346:CKR_RS04260
uniprot id: B9E006
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

583346:CKR RS03195
gene id: 583346:CKR_RS03195
uniprot id: B9DZF2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS05245
gene id: 583346:CKR_RS05245
uniprot id: B9E0J3
names: Similarity
messages: Belongs to the GerABKA family.

583346:CKR RS04540
gene id: 583346:CKR_RS04540
uniprot id: B9E061
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583346:CKR RS17020
gene id: 583346:CKR_RS17020
uniprot id: B9DWX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

583346:CKR RS15405
gene id: 583346:CKR_RS15405
uniprot id: B9E612
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

583346:CKR RS10825
gene id: 583346:CKR_RS10825
uniprot id: B9E3K6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

583346:CKR RS15085
gene id: 583346:CKR_RS15085
uniprot id: B9E5V9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

583346:CKR RS17640
gene id: 583346:CKR_RS17640
uniprot id: B9DX94
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

583346:CKR RS05710
gene id: 583346:CKR_RS05710
uniprot id: B9E0T3
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

583346:CKR RS17580
gene id: 583346:CKR_RS17580
uniprot id: B9DX82
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

583346:CKR RS04265
gene id: 583346:CKR_RS04265
uniprot id: B9E007
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

583346:CKR RS09935
gene id: 583346:CKR_RS09935
uniprot id: B9E340
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

583346:CKR RS12655
gene id: 583346:CKR_RS12655
uniprot id: B9E4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

583346:CKR RS03890
gene id: 583346:CKR_RS03890
uniprot id: B9DZT4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583346:CKR RS04200
gene id: 583346:CKR_RS04200
uniprot id: B9DZZ0
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

583346:CKR RS06055
gene id: 583346:CKR_RS06055
uniprot id: B9E101
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

583346:CKR RS14745
gene id: 583346:CKR_RS14745
uniprot id: B9E5P3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS06915
gene id: 583346:CKR_RS06915
uniprot id: B9E1H4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

583346:CKR RS14700
gene id: 583346:CKR_RS14700
uniprot id: B9E5N4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583346:CKR RS17980
gene id: 583346:CKR_RS17980
uniprot id: B9DXF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

583346:CKR RS17530
gene id: 583346:CKR_RS17530
uniprot id: B9DX72
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

583346:CKR RS11535
gene id: 583346:CKR_RS11535
uniprot id: B9E3Z5
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS18735
gene id: 583346:CKR_RS18735
uniprot id: B9E6F0
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

583346:CKR RS01060
gene id: 583346:CKR_RS01060
uniprot id: B9DYA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

583346:CKR RS11750
gene id: 583346:CKR_RS11750
uniprot id: B9E436
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS04500
gene id: 583346:CKR_RS04500
uniprot id: B9E054
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

583346:CKR RS09985
gene id: 583346:CKR_RS09985
uniprot id: B9E350
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

583346:CKR RS12115
gene id: 583346:CKR_RS12115
uniprot id: B9E4A6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

583346:CKR RS11305
gene id: 583346:CKR_RS11305
uniprot id: B9E3V0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

583346:CKR RS14830
gene id: 583346:CKR_RS14830
uniprot id: B9E5Q8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

583346:CKR RS06635
gene id: 583346:CKR_RS06635
uniprot id: B9E1B7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

583346:CKR RS02535
gene id: 583346:CKR_RS02535
uniprot id: B9DZ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

583346:CKR RS14505
gene id: 583346:CKR_RS14505
uniprot id: B9E5J7
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

583346:CKR RS12925
gene id: 583346:CKR_RS12925
uniprot id: B9E4Q9
names: Similarity
messages: Belongs to the leucine-binding protein family.

583346:CKR RS00215
gene id: 583346:CKR_RS00215
uniprot id: B9DXW0
names: Similarity
messages: Belongs to the citrate synthase family.

583346:CKR RS03290
gene id: 583346:CKR_RS03290
uniprot id: B9DZH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

583346:CKR RS13280
gene id: 583346:CKR_RS13280
uniprot id: B9E4X7
names: Similarity
messages: Belongs to the RNase H family.

583346:CKR RS05930
gene id: 583346:CKR_RS05930
uniprot id: B9E0X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS18635
gene id: 583346:CKR_RS18635
uniprot id: B9DXR6
names: Similarity
messages: Belongs to the ParB family.

583346:CKR RS02565
gene id: 583346:CKR_RS02565
uniprot id: B9DZ35
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

583346:CKR RS00350
gene id: 583346:CKR_RS00350
uniprot id: B9DXY1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583346:CKR RS15930
gene id: 583346:CKR_RS15930
uniprot id: B9E6A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

583346:CKR RS13005
gene id: 583346:CKR_RS13005
uniprot id: B9E4S3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

583346:CKR RS06790
gene id: 583346:CKR_RS06790
uniprot id: B9E1E8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

583346:CKR RS06905
gene id: 583346:CKR_RS06905
uniprot id: B9E1H2
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

583346:CKR RS13295
gene id: 583346:CKR_RS13295
uniprot id: B9E4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

583346:CKR RS17520
gene id: 583346:CKR_RS17520
uniprot id: B9DX70
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

583346:CKR RS10835
gene id: 583346:CKR_RS10835
uniprot id: B9E3K8
names: Similarity
messages: Belongs to the asparagine synthetase family.

583346:CKR RS09540
gene id: 583346:CKR_RS09540
uniprot id: B9E2W3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS06735
gene id: 583346:CKR_RS06735
uniprot id: B9E1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

583346:CKR RS00945
gene id: 583346:CKR_RS00945
uniprot id: B9DY79
names: Similarity
messages: Belongs to the CtsR family.

583346:CKR RS16520
gene id: 583346:CKR_RS16520
uniprot id: B9DWN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS00705
gene id: 583346:CKR_RS00705
uniprot id: B9DY45
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

583346:CKR RS12890
gene id: 583346:CKR_RS12890
uniprot id: B9E4Q2
names: Similarity
messages: Belongs to the transpeptidase family.

583346:CKR RS10100
gene id: 583346:CKR_RS10100
uniprot id: B9E371
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS13610
gene id: 583346:CKR_RS13610
uniprot id: B9E536
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS11685
gene id: 583346:CKR_RS11685
uniprot id: B9E424
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS11575
gene id: 583346:CKR_RS11575
uniprot id: B9E403
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

583346:CKR RS15145
gene id: 583346:CKR_RS15145
uniprot id: B9E5W6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS07750
gene id: 583346:CKR_RS07750
uniprot id: B9E1Z0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

583346:CKR RS11845
gene id: 583346:CKR_RS11845
uniprot id: B9E454
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS12960
gene id: 583346:CKR_RS12960
uniprot id: B9E4R5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

583346:CKR RS08120
gene id: 583346:CKR_RS08120
uniprot id: B9E261
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS06405
gene id: 583346:CKR_RS06405
uniprot id: B9E171
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

583346:CKR RS06070
gene id: 583346:CKR_RS06070
uniprot id: B9E104
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

583346:CKR RS18670
gene id: 583346:CKR_RS18670
uniprot id: B9DXS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

583346:CKR RS08625
gene id: 583346:CKR_RS08625
uniprot id: B9E2F3
names: Similarity
messages: Belongs to the P(II) protein family.

583346:CKR RS08700
gene id: 583346:CKR_RS08700
uniprot id: B9E2G8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

583346:CKR RS06900
gene id: 583346:CKR_RS06900
uniprot id: B9E1H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

583346:CKR RS04055
gene id: 583346:CKR_RS04055
uniprot id: B9DZW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

583346:CKR RS05715
gene id: 583346:CKR_RS05715
uniprot id: B9E0T4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

583346:CKR RS14080
gene id: 583346:CKR_RS14080
uniprot id: B9E5B6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

583346:CKR RS01145
gene id: 583346:CKR_RS01145
uniprot id: B9DYB7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

583346:CKR RS07880
gene id: 583346:CKR_RS07880
uniprot id: B9E214
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

583346:CKR RS01170
gene id: 583346:CKR_RS01170
uniprot id: B9DYC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

583346:CKR RS08020
gene id: 583346:CKR_RS08020
uniprot id: B9E241
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS05660
gene id: 583346:CKR_RS05660
uniprot id: B9E0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

583346:CKR RS13890
gene id: 583346:CKR_RS13890
uniprot id: B9E584
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

583346:CKR RS05615
gene id: 583346:CKR_RS05615
uniprot id: B9E0R4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS14530
gene id: 583346:CKR_RS14530
uniprot id: B9E5K2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

583346:CKR RS00240
gene id: 583346:CKR_RS00240
uniprot id: B9DXW5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

583346:CKR RS14860
gene id: 583346:CKR_RS14860
uniprot id: B9E5R4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583346:CKR RS07060
gene id: 583346:CKR_RS07060
uniprot id: B9E1K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

583346:CKR RS00740
gene id: 583346:CKR_RS00740
uniprot id: B9DY52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

583346:CKR RS00565
gene id: 583346:CKR_RS00565
uniprot id: B9DY16
names: Similarity
messages: Belongs to the peptidase S8 family.

583346:CKR RS08685
gene id: 583346:CKR_RS08685
uniprot id: B9E2G5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583346:CKR RS03740
gene id: 583346:CKR_RS03740
uniprot id: B9DZQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS12710
gene id: 583346:CKR_RS12710
uniprot id: B9E4L7
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS05090
gene id: 583346:CKR_RS05090
uniprot id: B9E0G2
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS10920
gene id: 583346:CKR_RS10920
uniprot id: B9E3M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

583346:CKR RS05455
gene id: 583346:CKR_RS05455
uniprot id: B9E0N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

583346:CKR RS06470
gene id: 583346:CKR_RS06470
uniprot id: B9E184
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583346:CKR RS02635
gene id: 583346:CKR_RS02635
uniprot id: B9DZ47
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

583346:CKR RS06850
gene id: 583346:CKR_RS06850
uniprot id: B9E1G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

583346:CKR RS03190
gene id: 583346:CKR_RS03190
uniprot id: B9DZF1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

583346:CKR RS16940
gene id: 583346:CKR_RS16940
uniprot id: B9DWW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

583346:CKR RS04340
gene id: 583346:CKR_RS04340
uniprot id: B9E022
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

583346:CKR RS15310
gene id: 583346:CKR_RS15310
uniprot id: B9E5Z5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

583346:CKR RS15975
gene id: 583346:CKR_RS15975
uniprot id: B9E6B4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

583346:CKR RS14735
gene id: 583346:CKR_RS14735
uniprot id: B9E5P1
names: Similarity
messages: Belongs to the EamA transporter family.

583346:CKR RS01985
gene id: 583346:CKR_RS01985
uniprot id: B9DYS7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583346:CKR RS07035
gene id: 583346:CKR_RS07035
uniprot id: B9E1J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

583346:CKR RS01055
gene id: 583346:CKR_RS01055
uniprot id: B9DY99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

583346:CKR RS17125
gene id: 583346:CKR_RS17125
uniprot id: B9DWZ9
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS12645
gene id: 583346:CKR_RS12645
uniprot id: B9E4K6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

583346:CKR RS03975
gene id: 583346:CKR_RS03975
uniprot id: B9DZV0
names: Similarity
messages: Belongs to the peptidase S58 family.

583346:CKR RS16135
gene id: 583346:CKR_RS16135
uniprot id: B9DWH6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

583346:CKR RS06380
gene id: 583346:CKR_RS06380
uniprot id: B9E166
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

583346:CKR RS17500
gene id: 583346:CKR_RS17500
uniprot id: B9DX66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

583346:CKR RS14435
gene id: 583346:CKR_RS14435
uniprot id: B9E5I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

583346:CKR RS04635
gene id: 583346:CKR_RS04635
uniprot id: B9E080
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

583346:CKR RS04400
gene id: 583346:CKR_RS04400
uniprot id: B9E034
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

583346:CKR RS16530
gene id: 583346:CKR_RS16530
uniprot id: B9DWN9
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

583346:CKR RS14725
gene id: 583346:CKR_RS14725
uniprot id: B9E5N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

583346:CKR RS03535
gene id: 583346:CKR_RS03535
uniprot id: B9DZL6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

583346:CKR RS14580
gene id: 583346:CKR_RS14580
uniprot id: B9E5L2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

583346:CKR RS04280
gene id: 583346:CKR_RS04280
uniprot id: B9E010
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

583346:CKR RS06385
gene id: 583346:CKR_RS06385
uniprot id: B9E167
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

583346:CKR RS00400
gene id: 583346:CKR_RS00400
uniprot id: B9DXZ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS08790
gene id: 583346:CKR_RS08790
uniprot id: B9E2I5
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS10845
gene id: 583346:CKR_RS10845
uniprot id: B9E3L0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

583346:CKR RS05325
gene id: 583346:CKR_RS05325
uniprot id: B9E0K9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS16885
gene id: 583346:CKR_RS16885
uniprot id: B9DWV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

583346:CKR RS06620
gene id: 583346:CKR_RS06620
uniprot id: B9E1B4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

583346:CKR RS02645
gene id: 583346:CKR_RS02645
uniprot id: B9DZ49
names: Similarity
messages: Belongs to the Tlp family.

583346:CKR RS02915
gene id: 583346:CKR_RS02915
uniprot id: B9DZ97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583346:CKR RS11565
gene id: 583346:CKR_RS11565
uniprot id: B9E401
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

583346:CKR RS02500
gene id: 583346:CKR_RS02500
uniprot id: B9DZ22
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

583346:CKR RS01255
gene id: 583346:CKR_RS01255
uniprot id: B9DYD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

583346:CKR RS14915
gene id: 583346:CKR_RS14915
uniprot id: B9E5S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

583346:CKR RS03680
gene id: 583346:CKR_RS03680
uniprot id: B9DZP4
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS01095
gene id: 583346:CKR_RS01095
uniprot id: B9DY93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

583346:CKR RS13475
gene id: 583346:CKR_RS13475
uniprot id: B9E513
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS17405
gene id: 583346:CKR_RS17405
uniprot id: B9DX52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

583346:CKR RS03640
gene id: 583346:CKR_RS03640
uniprot id: B9DZN6
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS10795
gene id: 583346:CKR_RS10795
uniprot id: B9E3K0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583346:CKR RS07755
gene id: 583346:CKR_RS07755
uniprot id: B9E1Z1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

583346:CKR RS12665
gene id: 583346:CKR_RS12665
uniprot id: B9E4L0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

583346:CKR RS15945
gene id: 583346:CKR_RS15945
uniprot id: B9E6A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

583346:CKR RS04820
gene id: 583346:CKR_RS04820
uniprot id: B9E0A8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

583346:CKR RS10645
gene id: 583346:CKR_RS10645
uniprot id: B9E3H4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

583346:CKR RS02250
gene id: 583346:CKR_RS02250
uniprot id: B9DYX5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

583346:CKR RS00005
gene id: 583346:CKR_RS00005
uniprot id: B9DXS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

583346:CKR RS13185
gene id: 583346:CKR_RS13185
uniprot id: B9E4V8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

583346:CKR RS16205
gene id: 583346:CKR_RS16205
uniprot id: B9DWJ0
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS06530
gene id: 583346:CKR_RS06530
uniprot id: B9E196
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

583346:CKR RS11155
gene id: 583346:CKR_RS11155
uniprot id: B9E3S0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS12670
gene id: 583346:CKR_RS12670
uniprot id: B9E4L1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

583346:CKR RS06395
gene id: 583346:CKR_RS06395
uniprot id: B9E169
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

583346:CKR RS06730
gene id: 583346:CKR_RS06730
uniprot id: B9E1D6
names: Similarity
messages: Belongs to the RemA family.

583346:CKR RS14875
gene id: 583346:CKR_RS14875
uniprot id: B9E5R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

583346:CKR RS12735
gene id: 583346:CKR_RS12735
uniprot id: B9E4M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

583346:CKR RS05830
gene id: 583346:CKR_RS05830
uniprot id: B9E0V7
names: Similarity
messages: Belongs to the transpeptidase family.

583346:CKR RS00420
gene id: 583346:CKR_RS00420
uniprot id: B9DXZ4
names: Similarity
messages: Belongs to the peptidase M18 family.

583346:CKR RS02985
gene id: 583346:CKR_RS02985
uniprot id: B9DZB1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

583346:CKR RS10090
gene id: 583346:CKR_RS10090
uniprot id: B9E369
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

583346:CKR RS04095
gene id: 583346:CKR_RS04095
uniprot id: B9DZX5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

583346:CKR RS06545
gene id: 583346:CKR_RS06545
uniprot id: B9E199
names: Similarity
messages: Belongs to the UPF0473 family.

583346:CKR RS01235
gene id: 583346:CKR_RS01235
uniprot id: B9DYD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

583346:CKR RS16010
gene id: 583346:CKR_RS16010
uniprot id: B9E6C1
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

583346:CKR RS07665
gene id: 583346:CKR_RS07665
uniprot id: B9E1X3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

583346:CKR RS15200
gene id: 583346:CKR_RS15200
uniprot id: B9E5X7
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

583346:CKR RS07580
gene id: 583346:CKR_RS07580
uniprot id: B9E1V6
names: Similarity
messages: Belongs to the peptidase M18 family.

583346:CKR RS16375
gene id: 583346:CKR_RS16375
uniprot id: B9DWL0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

583346:CKR RS08330
gene id: 583346:CKR_RS08330
uniprot id: B9E299
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

583346:CKR RS04180
gene id: 583346:CKR_RS04180
uniprot id: B9DZZ0
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

583346:CKR RS12725
gene id: 583346:CKR_RS12725
uniprot id: B9E4M0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

583346:CKR RS13710
gene id: 583346:CKR_RS13710
uniprot id: B9E554
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

583346:CKR RS00265
gene id: 583346:CKR_RS00265
uniprot id: B9DXW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

583346:CKR RS01405
gene id: 583346:CKR_RS01405
uniprot id: B9DYG3
names: Similarity
messages: Belongs to the peptidase C40 family.

583346:CKR RS04915
gene id: 583346:CKR_RS04915
uniprot id: B9E0C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

583346:CKR RS12855
gene id: 583346:CKR_RS12855
uniprot id: B9E4P5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

583346:CKR RS18245
gene id: 583346:CKR_RS18245
uniprot id: B9DXK1
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

583346:CKR RS14775
gene id: 583346:CKR_RS14775
uniprot id: B9E5P9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

583346:CKR RS07310
gene id: 583346:CKR_RS07310
uniprot id: B9E1Q3
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS08920
gene id: 583346:CKR_RS08920
uniprot id: B9E2L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

583346:CKR RS00545
gene id: 583346:CKR_RS00545
uniprot id: B9DY12
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

583346:CKR RS04940
gene id: 583346:CKR_RS04940
uniprot id: B9E0D2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

583346:CKR RS06720
gene id: 583346:CKR_RS06720
uniprot id: B9E1D4
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

583346:CKR RS00435
gene id: 583346:CKR_RS00435
uniprot id: B9DXZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

583346:CKR RS15000
gene id: 583346:CKR_RS15000
uniprot id: B9E5U2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

583346:CKR RS04920
gene id: 583346:CKR_RS04920
uniprot id: B9E0C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

583346:CKR RS05385
gene id: 583346:CKR_RS05385
uniprot id: B9E0M0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

583346:CKR RS03810
gene id: 583346:CKR_RS03810
uniprot id: B9DZR8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

583346:CKR RS06995
gene id: 583346:CKR_RS06995
uniprot id: B9E1J0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS01280
gene id: 583346:CKR_RS01280
uniprot id: B9DYE4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

583346:CKR RS06300
gene id: 583346:CKR_RS06300
uniprot id: B9E150
names: Similarity
messages: Belongs to the TrpF family.

583346:CKR RS05115
gene id: 583346:CKR_RS05115
uniprot id: B9E0G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583346:CKR RS15090
gene id: 583346:CKR_RS15090
uniprot id: B9E5W0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS17035
gene id: 583346:CKR_RS17035
uniprot id: B9DWY2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

583346:CKR RS09880
gene id: 583346:CKR_RS09880
uniprot id: B9E329
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

583346:CKR RS14790
gene id: 583346:CKR_RS14790
uniprot id: B9E5Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

583346:CKR RS06885
gene id: 583346:CKR_RS06885
uniprot id: B9E1G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

583346:CKR RS08590
gene id: 583346:CKR_RS08590
uniprot id: B9E2E6
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

583346:CKR RS03885
gene id: 583346:CKR_RS03885
uniprot id: B9DZT3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS10190
gene id: 583346:CKR_RS10190
uniprot id: B9E389
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

583346:CKR RS14520
gene id: 583346:CKR_RS14520
uniprot id: B9E5K0
names: Similarity
messages: Belongs to the P(II) protein family.

583346:CKR RS00210
gene id: 583346:CKR_RS00210
uniprot id: B9DXV9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583346:CKR RS03690
gene id: 583346:CKR_RS03690
uniprot id: B9DZP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

583346:CKR RS06695
gene id: 583346:CKR_RS06695
uniprot id: B9E1C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

583346:CKR RS06745
gene id: 583346:CKR_RS06745
uniprot id: B9E1D9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS02920
gene id: 583346:CKR_RS02920
uniprot id: B9DZ98
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

583346:CKR RS06810
gene id: 583346:CKR_RS06810
uniprot id: B9E1F3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

583346:CKR RS13250
gene id: 583346:CKR_RS13250
uniprot id: B9E4X1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS03505
gene id: 583346:CKR_RS03505
uniprot id: B9DZL0
names: Similarity
messages: Belongs to the peptidase S8 family.

583346:CKR RS06560
gene id: 583346:CKR_RS06560
uniprot id: B9E1A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

583346:CKR RS16915
gene id: 583346:CKR_RS16915
uniprot id: B9DWV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

583346:CKR RS18730
gene id: 583346:CKR_RS18730
uniprot id: B9E5Z6
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS01065
gene id: 583346:CKR_RS01065
uniprot id: B9DYA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

583346:CKR RS04395
gene id: 583346:CKR_RS04395
uniprot id: B9E033
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

583346:CKR RS14220
gene id: 583346:CKR_RS14220
uniprot id: B9E5E2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

583346:CKR RS02310
gene id: 583346:CKR_RS02310
uniprot id: B9DYY7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

583346:CKR RS12150
gene id: 583346:CKR_RS12150
uniprot id: B9E4B4
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS14895
gene id: 583346:CKR_RS14895
uniprot id: B9E5S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cytoplasm
messages: Homodimer or homotetramer.

583346:CKR RS13755
gene id: 583346:CKR_RS13755
uniprot id: B9E563
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

583346:CKR RS01265
gene id: 583346:CKR_RS01265
uniprot id: B9DYE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

583346:CKR RS06325
gene id: 583346:CKR_RS06325
uniprot id: B9E155
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

583346:CKR RS11695
gene id: 583346:CKR_RS11695
uniprot id: B9E426
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS03025
gene id: 583346:CKR_RS03025
uniprot id: B9DZB9
names: Similarity
messages: Belongs to the UPF0597 family.

583346:CKR RS15080
gene id: 583346:CKR_RS15080
uniprot id: B9E5V8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

583346:CKR RS05675
gene id: 583346:CKR_RS05675
uniprot id: B9E0S6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

583346:CKR RS05915
gene id: 583346:CKR_RS05915
uniprot id: B9E0X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

583346:CKR RS14390
gene id: 583346:CKR_RS14390
uniprot id: B9E5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

583346:CKR RS06855
gene id: 583346:CKR_RS06855
uniprot id: B9E1G2
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

583346:CKR RS08310
gene id: 583346:CKR_RS08310
uniprot id: B9E296
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

583346:CKR RS10965
gene id: 583346:CKR_RS10965
uniprot id: B9E3N3
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

583346:CKR RS01810
gene id: 583346:CKR_RS01810
uniprot id: B9DYP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

583346:CKR RS06475
gene id: 583346:CKR_RS06475
uniprot id: B9E185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583346:CKR RS05860
gene id: 583346:CKR_RS05860
uniprot id: B9E0W3
names: Similarity
messages: Belongs to the UPF0749 family.

583346:CKR RS01565
gene id: 583346:CKR_RS01565
uniprot id: B9DYJ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS07075
gene id: 583346:CKR_RS07075
uniprot id: B9E1K6
names: Similarity
messages: Belongs to the ribF family.

583346:CKR RS15775
gene id: 583346:CKR_RS15775
uniprot id: B9E674
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

583346:CKR RS06280
gene id: 583346:CKR_RS06280
uniprot id: B9E146
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

583346:CKR RS11895
gene id: 583346:CKR_RS11895
uniprot id: B9E464
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

583346:CKR RS07235
gene id: 583346:CKR_RS07235
uniprot id: B9E1N9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

583346:CKR RS08950
gene id: 583346:CKR_RS08950
uniprot id: B9E2L7
names: Subcellular Location Annotation
messages: Cytoplasm

583346:CKR RS15725
gene id: 583346:CKR_RS15725
uniprot id: B9E664
names: Similarity
messages: Belongs to the peptidase M16 family.

583346:CKR RS14555
gene id: 583346:CKR_RS14555
uniprot id: B9E5K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

583346:CKR RS11740
gene id: 583346:CKR_RS11740
uniprot id: B9E434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

583346:CKR RS01195
gene id: 583346:CKR_RS01195
uniprot id: B9DYC7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

583346:CKR RS17560
gene id: 583346:CKR_RS17560
uniprot id: B9DX78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

583346:CKR RS06585
gene id: 583346:CKR_RS06585
uniprot id: B9E1A7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

583346:CKR RS07025
gene id: 583346:CKR_RS07025
uniprot id: B9E1J6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

583346:CKR RS16920
gene id: 583346:CKR_RS16920
uniprot id: B9DWV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

583346:CKR RS07085
gene id: 583346:CKR_RS07085
uniprot id: B9E1K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

583346:CKR RS06295
gene id: 583346:CKR_RS06295
uniprot id: B9E149
names: Similarity
messages: Belongs to the TrpC family.

583346:CKR RS07415
gene id: 583346:CKR_RS07415
uniprot id: B9E1S3
names: Similarity
messages: Belongs to the thioesterase family.

583346:CKR RS06085
gene id: 583346:CKR_RS06085
uniprot id: B9E107
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

583346:CKR RS08715
gene id: 583346:CKR_RS08715
uniprot id: B9E2H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

583346:CKR RS05130
gene id: 583346:CKR_RS05130
uniprot id: B9E0H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583346:CKR RS00855
gene id: 583346:CKR_RS00855
uniprot id: B9DY69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS15130
gene id: 583346:CKR_RS15130
uniprot id: B9E5W3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583346:CKR RS10640
gene id: 583346:CKR_RS10640
uniprot id: B9E3H3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

583346:CKR RS07470
gene id: 583346:CKR_RS07470
uniprot id: B9E1T3
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS10145
gene id: 583346:CKR_RS10145
uniprot id: B9E380
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

583346:CKR RS05275
gene id: 583346:CKR_RS05275
uniprot id: B9E0J9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS11185
gene id: 583346:CKR_RS11185
uniprot id: B9E3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

583346:CKR RS14215
gene id: 583346:CKR_RS14215
uniprot id: B9E5E1
names: Similarity
messages: Belongs to the EamA transporter family.

583346:CKR RS14480
gene id: 583346:CKR_RS14480
uniprot id: B9E5J2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

583346:CKR RS06910
gene id: 583346:CKR_RS06910
uniprot id: B9E1H3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

583346:CKR RS14510
gene id: 583346:CKR_RS14510
uniprot id: B9E5J8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

583346:CKR RS02305
gene id: 583346:CKR_RS02305
uniprot id: B9DYY6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

583346:CKR RS09875
gene id: 583346:CKR_RS09875
uniprot id: B9E328
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

583346:CKR RS03555
gene id: 583346:CKR_RS03555
uniprot id: B9DZM0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

583346:CKR RS08655
gene id: 583346:CKR_RS08655
uniprot id: B9E2F9
names: Similarity
messages: Belongs to the serpin family.

583346:CKR RS07030
gene id: 583346:CKR_RS07030
uniprot id: B9E1J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

583346:CKR RS10025
gene id: 583346:CKR_RS10025
uniprot id: B9E358
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

583346:CKR RS13390
gene id: 583346:CKR_RS13390
uniprot id: B9E4Z7
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

583346:CKR RS04320
gene id: 583346:CKR_RS04320
uniprot id: B9E018
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

583346:CKR RS13165
gene id: 583346:CKR_RS13165
uniprot id: B9E4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

583346:CKR RS01500
gene id: 583346:CKR_RS01500
uniprot id: B9DYI1
names: Similarity
messages: Belongs to the class-I fumarase family.

583346:CKR RS02130
gene id: 583346:CKR_RS02130
uniprot id: B9DYV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

583346:CKR RS10125
gene id: 583346:CKR_RS10125
uniprot id: B9E376
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

583346:CKR RS06985
gene id: 583346:CKR_RS06985
uniprot id: B9E1I8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

583346:CKR RS07180
gene id: 583346:CKR_RS07180
uniprot id: B9E1M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

583346:CKR RS16870
gene id: 583346:CKR_RS16870
uniprot id: B9DWU9
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

583346:CKR RS05735
gene id: 583346:CKR_RS05735
uniprot id: B9E0T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

583346:CKR RS02210
gene id: 583346:CKR_RS02210
uniprot id: B9DYW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

583346:CKR RS18160
gene id: 583346:CKR_RS18160
uniprot id: B9DXI6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

583346:CKR RS16730
gene id: 583346:CKR_RS16730
uniprot id: B9DWS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

583346:CKR RS00585
gene id: 583346:CKR_RS00585
uniprot id: B9DY20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS03485
gene id: 583346:CKR_RS03485
uniprot id: B9DZK6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

583346:CKR RS03830
gene id: 583346:CKR_RS03830
uniprot id: B9DZS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583346:CKR RS17010
gene id: 583346:CKR_RS17010
uniprot id: B9DWX7
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

583346:CKR RS16085
gene id: 583346:CKR_RS16085
uniprot id: B9E6D6
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS14890
gene id: 583346:CKR_RS14890
uniprot id: B9E5S0
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

583346:CKR RS00845
gene id: 583346:CKR_RS00845
uniprot id: B9DY67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

583346:CKR RS15780
gene id: 583346:CKR_RS15780
uniprot id: B9E675
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

583346:CKR RS07150
gene id: 583346:CKR_RS07150
uniprot id: B9E1M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

583346:CKR RS11070
gene id: 583346:CKR_RS11070
uniprot id: B9E3Q4
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS00700
gene id: 583346:CKR_RS00700
uniprot id: B9DY44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

583346:CKR RS11335
gene id: 583346:CKR_RS11335
uniprot id: B9E3V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

583346:CKR RS17470
gene id: 583346:CKR_RS17470
uniprot id: B9DX60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

583346:CKR RS04245
gene id: 583346:CKR_RS04245
uniprot id: B9E003
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

583346:CKR RS07940
gene id: 583346:CKR_RS07940
uniprot id: B9E225
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

583346:CKR RS10540
gene id: 583346:CKR_RS10540
uniprot id: B9E3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

583346:CKR RS01870
gene id: 583346:CKR_RS01870
uniprot id: B9DYQ4
names: Similarity
messages: Belongs to the Ahb/Nir family.

583346:CKR RS03820
gene id: 583346:CKR_RS03820
uniprot id: B9DZS0
names: Similarity
messages: Belongs to the UPF0237 family.

583346:CKR RS13055
gene id: 583346:CKR_RS13055
uniprot id: B9E4T2
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

583346:CKR RS10550
gene id: 583346:CKR_RS10550
uniprot id: B9E3F5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583346:CKR RS10395
gene id: 583346:CKR_RS10395
uniprot id: B9E3C9
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS09600
gene id: 583346:CKR_RS09600
uniprot id: B9E2X5
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS13085
gene id: 583346:CKR_RS13085
uniprot id: B9E4T8
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

583346:CKR RS17985
gene id: 583346:CKR_RS17985
uniprot id: B9DXF9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

583346:CKR RS01660
gene id: 583346:CKR_RS01660
uniprot id: B9DYL4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

583346:CKR RS08825
gene id: 583346:CKR_RS08825
uniprot id: B9E2J2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583346:CKR RS13465
gene id: 583346:CKR_RS13465
uniprot id: B9E511
names: Similarity
messages: Belongs to the GerABKA family.

583346:CKR RS16390
gene id: 583346:CKR_RS16390
uniprot id: B9DWL3
names: Similarity
messages: Belongs to the HypE family.

583346:CKR RS12320
gene id: 583346:CKR_RS12320
uniprot id: B9E4E6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS17330
gene id: 583346:CKR_RS17330
uniprot id: B9DX36
names: Similarity
messages: Belongs to the EamA transporter family.

583346:CKR RS12430
gene id: 583346:CKR_RS12430
uniprot id: B9E4G7
names: Similarity
messages: Belongs to the peptidase S14 family.

583346:CKR RS04000
gene id: 583346:CKR_RS04000
uniprot id: B9DZV5
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS11795
gene id: 583346:CKR_RS11795
uniprot id: B9E445
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

583346:CKR RS16500
gene id: 583346:CKR_RS16500
uniprot id: B9DWN3
names: Similarity
messages: Belongs to the transglycosylase Slt family.

583346:CKR RS02685
gene id: 583346:CKR_RS02685
uniprot id: B9DZ57
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS03660
gene id: 583346:CKR_RS03660
uniprot id: B9DZP0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

583346:CKR RS18010
gene id: 583346:CKR_RS18010
uniprot id: B9DXG4
names: Similarity
messages: Belongs to the thymidylate kinase family.

583346:CKR RS17480
gene id: 583346:CKR_RS17480
uniprot id: B9DX62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

583346:CKR RS11285
gene id: 583346:CKR_RS11285
uniprot id: B9E3U6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

583346:CKR RS05015
gene id: 583346:CKR_RS05015
uniprot id: B9E0E7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583346:CKR RS11745
gene id: 583346:CKR_RS11745
uniprot id: B9E435
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS09585
gene id: 583346:CKR_RS09585
uniprot id: B9E2X2
names: Similarity
messages: Belongs to the HepT RNase toxin family.

583346:CKR RS02215
gene id: 583346:CKR_RS02215
uniprot id: B9DYW8
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

583346:CKR RS06330
gene id: 583346:CKR_RS06330
uniprot id: B9E156
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS18725
gene id: 583346:CKR_RS18725
uniprot id: B9E6E8
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS18505
gene id: 583346:CKR_RS18505
uniprot id: B9DXP3
names: Similarity
messages: Belongs to the peptidase A24 family.

583346:CKR RS06400
gene id: 583346:CKR_RS06400
uniprot id: B9E170
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

583346:CKR RS13040
gene id: 583346:CKR_RS13040
uniprot id: B9E4S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

583346:CKR RS03275
gene id: 583346:CKR_RS03275
uniprot id: B9DZG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583346:CKR RS18080
gene id: 583346:CKR_RS18080
uniprot id: B9DXH5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

583346:CKR RS01670
gene id: 583346:CKR_RS01670
uniprot id: B9DYL5
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

583346:CKR RS04960
gene id: 583346:CKR_RS04960
uniprot id: B9E0D6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

583346:CKR RS08710
gene id: 583346:CKR_RS08710
uniprot id: B9E2H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

583346:CKR RS07365
gene id: 583346:CKR_RS07365
uniprot id: B9E1R3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS02255
gene id: 583346:CKR_RS02255
uniprot id: B9DYX6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

583346:CKR RS16645
gene id: 583346:CKR_RS16645
uniprot id: B9DWR1
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

583346:CKR RS06675
gene id: 583346:CKR_RS06675
uniprot id: B9E1C5
names: Similarity
messages: Belongs to the UPF0111 family.

583346:CKR RS03755
gene id: 583346:CKR_RS03755
uniprot id: B9DZQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

583346:CKR RS07995
gene id: 583346:CKR_RS07995
uniprot id: B9E236
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

583346:CKR RS17555
gene id: 583346:CKR_RS17555
uniprot id: B9DX77
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

583346:CKR RS17920
gene id: 583346:CKR_RS17920
uniprot id: B9DXE7
names: Similarity
messages: Belongs to the PspA/IM30 family.

583346:CKR RS12215
gene id: 583346:CKR_RS12215
uniprot id: B9E4C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

583346:CKR RS17055
gene id: 583346:CKR_RS17055
uniprot id: B9DWY6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

583346:CKR RS17440
gene id: 583346:CKR_RS17440
uniprot id: B9DX54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS03620
gene id: 583346:CKR_RS03620
uniprot id: B9DZN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

583346:CKR RS08735
gene id: 583346:CKR_RS08735
uniprot id: B9E2H5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

583346:CKR RS06740
gene id: 583346:CKR_RS06740
uniprot id: B9E1D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

583346:CKR RS04070
gene id: 583346:CKR_RS04070
uniprot id: B9DZX0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

583346:CKR RS08835
gene id: 583346:CKR_RS08835
uniprot id: B9E2J4
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

583346:CKR RS09995
gene id: 583346:CKR_RS09995
uniprot id: B9E352
names: Similarity
messages: Belongs to the UPF0473 family.

583346:CKR RS01530
gene id: 583346:CKR_RS01530
uniprot id: B9DYI7
names: Similarity
messages: Belongs to the thioredoxin family.

583346:CKR RS10210
gene id: 583346:CKR_RS10210
uniprot id: B9E393
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

583346:CKR RS08235
gene id: 583346:CKR_RS08235
uniprot id: B9E281
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

583346:CKR RS12995
gene id: 583346:CKR_RS12995
uniprot id: B9E4S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

583346:CKR RS07945
gene id: 583346:CKR_RS07945
uniprot id: B9E226
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

583346:CKR RS02265
gene id: 583346:CKR_RS02265
uniprot id: B9DYX8
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

583346:CKR RS03875
gene id: 583346:CKR_RS03875
uniprot id: B9DZT1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

583346:CKR RS05020
gene id: 583346:CKR_RS05020
uniprot id: B9E0E8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

583346:CKR RS16830
gene id: 583346:CKR_RS16830
uniprot id: B9DWU2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS06290
gene id: 583346:CKR_RS06290
uniprot id: B9E148
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

583346:CKR RS18745
gene id: 583346:CKR_RS18745
uniprot id: B9E6F2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

583346:CKR RS13420
gene id: 583346:CKR_RS13420
uniprot id: B9E502
names: Similarity
messages: Belongs to the CFA/CMAS family.

583346:CKR RS04945
gene id: 583346:CKR_RS04945
uniprot id: B9E0D3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

583346:CKR RS04490
gene id: 583346:CKR_RS04490
uniprot id: B9E052
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

583346:CKR RS12910
gene id: 583346:CKR_RS12910
uniprot id: B9E4Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

583346:CKR RS16930
gene id: 583346:CKR_RS16930
uniprot id: B9DWW1
names: Similarity
messages: Belongs to the peptidase S41A family.

583346:CKR RS16190
gene id: 583346:CKR_RS16190
uniprot id: B9DWI7
names: Similarity
messages: Belongs to the EamA transporter family.

583346:CKR RS17830
gene id: 583346:CKR_RS17830
uniprot id: B9DXC9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

583346:CKR RS11430
gene id: 583346:CKR_RS11430
uniprot id: B9E3X4
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS00725
gene id: 583346:CKR_RS00725
uniprot id: B9DY49
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS12920
gene id: 583346:CKR_RS12920
uniprot id: B9E4Q8
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS07215
gene id: 583346:CKR_RS07215
uniprot id: B9E1N5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS10240
gene id: 583346:CKR_RS10240
uniprot id: B9E399
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

583346:CKR RS04375
gene id: 583346:CKR_RS04375
uniprot id: B9E029
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

583346:CKR RS11260
gene id: 583346:CKR_RS11260
uniprot id: B9E3U1
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

583346:CKR RS00560
gene id: 583346:CKR_RS00560
uniprot id: B9DY15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

583346:CKR RS04250
gene id: 583346:CKR_RS04250
uniprot id: B9E004
names: Similarity
messages: Belongs to the UPF0758 family.

583346:CKR RS08725
gene id: 583346:CKR_RS08725
uniprot id: B9E2H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

583346:CKR RS09550
gene id: 583346:CKR_RS09550
uniprot id: B9E2W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

583346:CKR RS12915
gene id: 583346:CKR_RS12915
uniprot id: B9E4Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

583346:CKR RS05820
gene id: 583346:CKR_RS05820
uniprot id: B9E0V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

583346:CKR RS09865
gene id: 583346:CKR_RS09865
uniprot id: B9E326
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

583346:CKR RS17285
gene id: 583346:CKR_RS17285
uniprot id: B9DX28
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

583346:CKR RS04615
gene id: 583346:CKR_RS04615
uniprot id: B9E076
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS03745
gene id: 583346:CKR_RS03745
uniprot id: B9DZQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

583346:CKR RS00955
gene id: 583346:CKR_RS00955
uniprot id: B9DY81
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

583346:CKR RS13720
gene id: 583346:CKR_RS13720
uniprot id: B9E556
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

583346:CKR RS07625
gene id: 583346:CKR_RS07625
uniprot id: B9E1W5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

583346:CKR RS01110
gene id: 583346:CKR_RS01110
uniprot id: B9DYB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

583346:CKR RS12940
gene id: 583346:CKR_RS12940
uniprot id: B9E4R2
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS13735
gene id: 583346:CKR_RS13735
uniprot id: B9E559
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

583346:CKR RS00635
gene id: 583346:CKR_RS00635
uniprot id: B9DY31
names: Similarity
messages: Belongs to the glutamine synthetase family.

583346:CKR RS16255
gene id: 583346:CKR_RS16255
uniprot id: B9DWK0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

583346:CKR RS01820
gene id: 583346:CKR_RS01820
uniprot id: B9DYP4
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS07285
gene id: 583346:CKR_RS07285
uniprot id: B9E1P8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583346:CKR RS10130
gene id: 583346:CKR_RS10130
uniprot id: B9E377
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

583346:CKR RS05065
gene id: 583346:CKR_RS05065
uniprot id: B9E0F7
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS07190
gene id: 583346:CKR_RS07190
uniprot id: B9E1M9
names: Similarity
messages: Belongs to the peptidase S11 family.

583346:CKR RS07565
gene id: 583346:CKR_RS07565
uniprot id: B9E1V3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS06500
gene id: 583346:CKR_RS06500
uniprot id: B9E190
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

583346:CKR RS05670
gene id: 583346:CKR_RS05670
uniprot id: B9E0S5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

583346:CKR RS04355
gene id: 583346:CKR_RS04355
uniprot id: B9E025
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

583346:CKR RS18600
gene id: 583346:CKR_RS18600
uniprot id: B9DXQ9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS12945
gene id: 583346:CKR_RS12945
uniprot id: B9E4R3
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS07925
gene id: 583346:CKR_RS07925
uniprot id: B9E223
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583346:CKR RS13060
gene id: 583346:CKR_RS13060
uniprot id: B9E4T3
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

583346:CKR RS13210
gene id: 583346:CKR_RS13210
uniprot id: B9E4W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

583346:CKR RS01800
gene id: 583346:CKR_RS01800
uniprot id: B9DYP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

583346:CKR RS16875
gene id: 583346:CKR_RS16875
uniprot id: B9DWV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

583346:CKR RS06990
gene id: 583346:CKR_RS06990
uniprot id: B9E1I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

583346:CKR RS03165
gene id: 583346:CKR_RS03165
uniprot id: B9DZE7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS05185
gene id: 583346:CKR_RS05185
uniprot id: B9E0I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

583346:CKR RS16165
gene id: 583346:CKR_RS16165
uniprot id: B9DWI2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

583346:CKR RS16695
gene id: 583346:CKR_RS16695
uniprot id: B9DWS0
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS14355
gene id: 583346:CKR_RS14355
uniprot id: B9E5G7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS17525
gene id: 583346:CKR_RS17525
uniprot id: B9DX71
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

583346:CKR RS03675
gene id: 583346:CKR_RS03675
uniprot id: B9DZP3
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

583346:CKR RS04495
gene id: 583346:CKR_RS04495
uniprot id: B9E053
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

583346:CKR RS07655
gene id: 583346:CKR_RS07655
uniprot id: B9E1X1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

583346:CKR RS05240
gene id: 583346:CKR_RS05240
uniprot id: B9E0J2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

583346:CKR RS01240
gene id: 583346:CKR_RS01240
uniprot id: B9DYD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

583346:CKR RS05490
gene id: 583346:CKR_RS05490
uniprot id: B9E0P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

583346:CKR RS14940
gene id: 583346:CKR_RS14940
uniprot id: B9E5T0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

583346:CKR RS02990
gene id: 583346:CKR_RS02990
uniprot id: B9DZB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

583346:CKR RS07040
gene id: 583346:CKR_RS07040
uniprot id: B9E1J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

583346:CKR RS09825
gene id: 583346:CKR_RS09825
uniprot id: B9E318
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

583346:CKR RS06870
gene id: 583346:CKR_RS06870
uniprot id: B9E1G5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

583346:CKR RS09795
gene id: 583346:CKR_RS09795
uniprot id: B9E312
names: Similarity
messages: Belongs to the polysaccharide synthase family.

583346:CKR RS00750
gene id: 583346:CKR_RS00750
uniprot id: B9DY54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

583346:CKR RS06805
gene id: 583346:CKR_RS06805
uniprot id: B9E1F2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

583346:CKR RS04730
gene id: 583346:CKR_RS04730
uniprot id: B9E094
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

583346:CKR RS06760
gene id: 583346:CKR_RS06760
uniprot id: B9E1E2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

583346:CKR RS06615
gene id: 583346:CKR_RS06615
uniprot id: B9E1B3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

583346:CKR RS01210
gene id: 583346:CKR_RS01210
uniprot id: B9DYD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

583346:CKR RS08285
gene id: 583346:CKR_RS08285
uniprot id: B9E291
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS06370
gene id: 583346:CKR_RS06370
uniprot id: B9E164
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

583346:CKR RS16245
gene id: 583346:CKR_RS16245
uniprot id: B9DWJ8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583346:CKR RS02295
gene id: 583346:CKR_RS02295
uniprot id: B9DYY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

583346:CKR RS01225
gene id: 583346:CKR_RS01225
uniprot id: B9DYD3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

583346:CKR RS14825
gene id: 583346:CKR_RS14825
uniprot id: B9E5Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

583346:CKR RS05370
gene id: 583346:CKR_RS05370
uniprot id: B9E0L7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS14800
gene id: 583346:CKR_RS14800
uniprot id: B9E5Q3
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

583346:CKR RS04255
gene id: 583346:CKR_RS04255
uniprot id: B9E005
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS07080
gene id: 583346:CKR_RS07080
uniprot id: B9E1K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

583346:CKR RS05110
gene id: 583346:CKR_RS05110
uniprot id: B9E0G6
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

583346:CKR RS14885
gene id: 583346:CKR_RS14885
uniprot id: B9E5R9
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

583346:CKR RS07100
gene id: 583346:CKR_RS07100
uniprot id: B9E1L1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

583346:CKR RS15720
gene id: 583346:CKR_RS15720
uniprot id: B9E663
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

583346:CKR RS01560
gene id: 583346:CKR_RS01560
uniprot id: B9DYJ3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

583346:CKR RS02140
gene id: 583346:CKR_RS02140
uniprot id: B9DYV3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

583346:CKR RS01030
gene id: 583346:CKR_RS01030
uniprot id: B9DY94
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

583346:CKR RS05835
gene id: 583346:CKR_RS05835
uniprot id: B9E0V8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS11885
gene id: 583346:CKR_RS11885
uniprot id: B9E462
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS00640
gene id: 583346:CKR_RS00640
uniprot id: B9DY32
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

583346:CKR RS01515
gene id: 583346:CKR_RS01515
uniprot id: B9DYI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

583346:CKR RS18040
gene id: 583346:CKR_RS18040
uniprot id: B9DXH0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

583346:CKR RS11755
gene id: 583346:CKR_RS11755
uniprot id: B9E437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spermidine/spermine synthase family.
messages: Cell membrane

583346:CKR RS17490
gene id: 583346:CKR_RS17490
uniprot id: B9DX64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

583346:CKR RS04970
gene id: 583346:CKR_RS04970
uniprot id: B9E0D8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS03600
gene id: 583346:CKR_RS03600
uniprot id: B9DZM9
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

583346:CKR RS07170
gene id: 583346:CKR_RS07170
uniprot id: B9E1M5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

583346:CKR RS01180
gene id: 583346:CKR_RS01180
uniprot id: B9DYC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

583346:CKR RS11810
gene id: 583346:CKR_RS11810
uniprot id: B9E448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

583346:CKR RS04510
gene id: 583346:CKR_RS04510
uniprot id: B9E056
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

583346:CKR RS15925
gene id: 583346:CKR_RS15925
uniprot id: B9E6A4
names: Similarity
messages: Belongs to the P(II) protein family.

583346:CKR RS17940
gene id: 583346:CKR_RS17940
uniprot id: B9DXF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

583346:CKR RS12065
gene id: 583346:CKR_RS12065
uniprot id: B9E495
names: Similarity
messages: Belongs to the SecB family.

583346:CKR RS03235
gene id: 583346:CKR_RS03235
uniprot id: B9DZG0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS02300
gene id: 583346:CKR_RS02300
uniprot id: B9DYY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

583346:CKR RS01215
gene id: 583346:CKR_RS01215
uniprot id: B9DYD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

583346:CKR RS17270
gene id: 583346:CKR_RS17270
uniprot id: B9DX25
names: Similarity
messages: Belongs to the NadC/ModD family.

583346:CKR RS06050
gene id: 583346:CKR_RS06050
uniprot id: B9E100
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

583346:CKR RS13600
gene id: 583346:CKR_RS13600
uniprot id: B9E534
names: Subcellular Location Annotation
messages: Cytoplasm

583346:CKR RS08370
gene id: 583346:CKR_RS08370
uniprot id: B9E2A6
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

583346:CKR RS08510
gene id: 583346:CKR_RS08510
uniprot id: B9E2D1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

583346:CKR RS04965
gene id: 583346:CKR_RS04965
uniprot id: B9E0D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

583346:CKR RS05905
gene id: 583346:CKR_RS05905
uniprot id: B9E0X2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

583346:CKR RS09915
gene id: 583346:CKR_RS09915
uniprot id: B9E336
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

583346:CKR RS01620
gene id: 583346:CKR_RS01620
uniprot id: B9DYK6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

583346:CKR RS07340
gene id: 583346:CKR_RS07340
uniprot id: B9E1Q9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

583346:CKR RS13105
gene id: 583346:CKR_RS13105
uniprot id: B9E4U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

583346:CKR RS15510
gene id: 583346:CKR_RS15510
uniprot id: B9E627
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

583346:CKR RS04385
gene id: 583346:CKR_RS04385
uniprot id: B9E031
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS04995
gene id: 583346:CKR_RS04995
uniprot id: B9E0E3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS11470
gene id: 583346:CKR_RS11470
uniprot id: B9E3Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

583346:CKR RS10985
gene id: 583346:CKR_RS10985
uniprot id: B9E3N7
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

583346:CKR RS14325
gene id: 583346:CKR_RS14325
uniprot id: B9E5G1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS13760
gene id: 583346:CKR_RS13760
uniprot id: B9E564
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

583346:CKR RS10250
gene id: 583346:CKR_RS10250
uniprot id: B9E3A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

583346:CKR RS09535
gene id: 583346:CKR_RS09535
uniprot id: B9E2W2
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS16120
gene id: 583346:CKR_RS16120
uniprot id: B9E6E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

583346:CKR RS13740
gene id: 583346:CKR_RS13740
uniprot id: B9E560
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

583346:CKR RS14770
gene id: 583346:CKR_RS14770
uniprot id: B9E5P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS18665
gene id: 583346:CKR_RS18665
uniprot id: B9DXS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

583346:CKR RS04930
gene id: 583346:CKR_RS04930
uniprot id: B9E0D0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583346:CKR RS08910
gene id: 583346:CKR_RS08910
uniprot id: B9E2K9
names: Similarity
messages: Belongs to the cyt1/cyt2 endotoxin family.

583346:CKR RS15835
gene id: 583346:CKR_RS15835
uniprot id: B9E686
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

583346:CKR RS03455
gene id: 583346:CKR_RS03455
uniprot id: B9DZK0
names: Subcellular Location Annotation
messages: Cytoplasm

583346:CKR RS14820
gene id: 583346:CKR_RS14820
uniprot id: B9E5Q6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

583346:CKR RS16955
gene id: 583346:CKR_RS16955
uniprot id: B9DWW6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

583346:CKR RS16405
gene id: 583346:CKR_RS16405
uniprot id: B9DWL5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

583346:CKR RS10295
gene id: 583346:CKR_RS10295
uniprot id: B9E3B0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583346:CKR RS16265
gene id: 583346:CKR_RS16265
uniprot id: B9DWK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

583346:CKR RS06975
gene id: 583346:CKR_RS06975
uniprot id: B9E1I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

583346:CKR RS06630
gene id: 583346:CKR_RS06630
uniprot id: B9E1B6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

583346:CKR RS08345
gene id: 583346:CKR_RS08345
uniprot id: B9E2A2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

583346:CKR RS10300
gene id: 583346:CKR_RS10300
uniprot id: B9E3B1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

583346:CKR RS10360
gene id: 583346:CKR_RS10360
uniprot id: B9E3C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

583346:CKR RS10500
gene id: 583346:CKR_RS10500
uniprot id: B9E3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

583346:CKR RS07385
gene id: 583346:CKR_RS07385
uniprot id: B9E1R7
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS01910
gene id: 583346:CKR_RS01910
uniprot id: B9DYR2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS00890
gene id: 583346:CKR_RS00890
uniprot id: B9DY75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

583346:CKR RS07650
gene id: 583346:CKR_RS07650
uniprot id: B9E1X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

583346:CKR RS06090
gene id: 583346:CKR_RS06090
uniprot id: B9E108
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

583346:CKR RS13765
gene id: 583346:CKR_RS13765
uniprot id: B9E565
names: Similarity
messages: Belongs to the ThiD family.

583346:CKR RS16995
gene id: 583346:CKR_RS16995
uniprot id: B9DWX4
names: Similarity
messages: Belongs to the SleB family.

583346:CKR RS01570
gene id: 583346:CKR_RS01570
uniprot id: B9DYJ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS07980
gene id: 583346:CKR_RS07980
uniprot id: B9E233
names: Similarity
messages: Belongs to the LOG family.

583346:CKR RS11030
gene id: 583346:CKR_RS11030
uniprot id: B9E3P6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS05780
gene id: 583346:CKR_RS05780
uniprot id: B9E0U7
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

583346:CKR RS08585
gene id: 583346:CKR_RS08585
uniprot id: B9E2E5
names: Function
names: Subunit
messages: Hexamer of two alpha, two beta, and two delta chains.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.

583346:CKR RS15680
gene id: 583346:CKR_RS15680
uniprot id: B9E655
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

583346:CKR RS01135
gene id: 583346:CKR_RS01135
uniprot id: B9DYB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

583346:CKR RS12185
gene id: 583346:CKR_RS12185
uniprot id: B9E4C1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS14740
gene id: 583346:CKR_RS14740
uniprot id: B9E5P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS05530
gene id: 583346:CKR_RS05530
uniprot id: B9E0P8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS13675
gene id: 583346:CKR_RS13675
uniprot id: B9E548
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

583346:CKR RS04450
gene id: 583346:CKR_RS04450
uniprot id: B9E044
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

583346:CKR RS17460
gene id: 583346:CKR_RS17460
uniprot id: B9DX58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS06235
gene id: 583346:CKR_RS06235
uniprot id: B9E137
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583346:CKR RS06535
gene id: 583346:CKR_RS06535
uniprot id: B9E197
names: Similarity
messages: Belongs to the UPF0297 family.

583346:CKR RS06770
gene id: 583346:CKR_RS06770
uniprot id: B9E1E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

583346:CKR RS01830
gene id: 583346:CKR_RS01830
uniprot id: B9DYP6
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

583346:CKR RS07465
gene id: 583346:CKR_RS07465
uniprot id: B9E1T2
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS18595
gene id: 583346:CKR_RS18595
uniprot id: B9DXQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

583346:CKR RS18650
gene id: 583346:CKR_RS18650
uniprot id: B9DXR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

583346:CKR RS16210
gene id: 583346:CKR_RS16210
uniprot id: B9DWJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

583346:CKR RS07765
gene id: 583346:CKR_RS07765
uniprot id: B9E1Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

583346:CKR RS09695
gene id: 583346:CKR_RS09695
uniprot id: B9E2Z3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

583346:CKR RS09965
gene id: 583346:CKR_RS09965
uniprot id: B9E346
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

583346:CKR RS08030
gene id: 583346:CKR_RS08030
uniprot id: B9E243
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

583346:CKR RS17245
gene id: 583346:CKR_RS17245
uniprot id: B9DX21
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS01700
gene id: 583346:CKR_RS01700
uniprot id: B9DYM0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

583346:CKR RS04910
gene id: 583346:CKR_RS04910
uniprot id: B9E0C6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

583346:CKR RS12535
gene id: 583346:CKR_RS12535
uniprot id: B9E4I5
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

583346:CKR RS17515
gene id: 583346:CKR_RS17515
uniprot id: B9DX69
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

583346:CKR RS01200
gene id: 583346:CKR_RS01200
uniprot id: B9DYC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

583346:CKR RS10610
gene id: 583346:CKR_RS10610
uniprot id: B9E3G7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS13050
gene id: 583346:CKR_RS13050
uniprot id: B9E4T1
names: Similarity
messages: Belongs to the GerABKA family.

583346:CKR RS00770
gene id: 583346:CKR_RS00770
uniprot id: B9DY58
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

583346:CKR RS08875
gene id: 583346:CKR_RS08875
uniprot id: B9E2K2
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

583346:CKR RS12715
gene id: 583346:CKR_RS12715
uniprot id: B9E4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

583346:CKR RS13480
gene id: 583346:CKR_RS13480
uniprot id: B9E514
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

583346:CKR RS02180
gene id: 583346:CKR_RS02180
uniprot id: B9DYW1
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

583346:CKR RS08580
gene id: 583346:CKR_RS08580
uniprot id: B9E2E4
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

583346:CKR RS04025
gene id: 583346:CKR_RS04025
uniprot id: B9DZW0
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS18620
gene id: 583346:CKR_RS18620
uniprot id: B9DXR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

583346:CKR RS16445
gene id: 583346:CKR_RS16445
uniprot id: B9DWM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

583346:CKR RS05485
gene id: 583346:CKR_RS05485
uniprot id: B9E0N9
names: Similarity
messages: Belongs to the GSP E family.

583346:CKR RS05545
gene id: 583346:CKR_RS05545
uniprot id: B9E0Q1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583346:CKR RS14955
gene id: 583346:CKR_RS14955
uniprot id: B9E5T3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

583346:CKR RS00590
gene id: 583346:CKR_RS00590
uniprot id: B9DY21
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

583346:CKR RS13180
gene id: 583346:CKR_RS13180
uniprot id: B9E4V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

583346:CKR RS16765
gene id: 583346:CKR_RS16765
uniprot id: B9DWT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

583346:CKR RS06190
gene id: 583346:CKR_RS06190
uniprot id: B9E128
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

583346:CKR RS04610
gene id: 583346:CKR_RS04610
uniprot id: B9E075
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

583346:CKR RS11705
gene id: 583346:CKR_RS11705
uniprot id: B9E428
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

583346:CKR RS10855
gene id: 583346:CKR_RS10855
uniprot id: B9E3L2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

583346:CKR RS17630
gene id: 583346:CKR_RS17630
uniprot id: B9DX92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

583346:CKR RS00030
gene id: 583346:CKR_RS00030
uniprot id: B9DXT2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

583346:CKR RS04465
gene id: 583346:CKR_RS04465
uniprot id: B9E047
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

583346:CKR RS04505
gene id: 583346:CKR_RS04505
uniprot id: B9E055
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

583346:CKR RS06835
gene id: 583346:CKR_RS06835
uniprot id: B9E1F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

583346:CKR RS03685
gene id: 583346:CKR_RS03685
uniprot id: B9DZP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

583346:CKR RS08035
gene id: 583346:CKR_RS08035
uniprot id: B9E244
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

583346:CKR RS07760
gene id: 583346:CKR_RS07760
uniprot id: B9E1Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

583346:CKR RS05765
gene id: 583346:CKR_RS05765
uniprot id: B9E0U4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

583346:CKR RS02100
gene id: 583346:CKR_RS02100
uniprot id: B9DYU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

583346:CKR RS05360
gene id: 583346:CKR_RS05360
uniprot id: B9E0L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

583346:CKR RS00870
gene id: 583346:CKR_RS00870
uniprot id: B9DY72
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

583346:CKR RS18115
gene id: 583346:CKR_RS18115
uniprot id: B9DXH8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

583346:CKR RS07090
gene id: 583346:CKR_RS07090
uniprot id: B9E1K9
names: Similarity
messages: Belongs to the peptidase M16 family.

583346:CKR RS05560
gene id: 583346:CKR_RS05560
uniprot id: B9E0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

583346:CKR RS16425
gene id: 583346:CKR_RS16425
uniprot id: B9DWL9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

583346:CKR RS09145
gene id: 583346:CKR_RS09145
uniprot id: B9E2P9
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

583346:CKR RS08090
gene id: 583346:CKR_RS08090
uniprot id: B9E255
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS09005
gene id: 583346:CKR_RS09005
uniprot id: B9E2M8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

583346:CKR RS00505
gene id: 583346:CKR_RS00505
uniprot id: B9DY04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

583346:CKR RS14500
gene id: 583346:CKR_RS14500
uniprot id: B9E5J6
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

583346:CKR RS08265
gene id: 583346:CKR_RS08265
uniprot id: B9E287
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

583346:CKR RS01230
gene id: 583346:CKR_RS01230
uniprot id: B9DYD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

583346:CKR RS06185
gene id: 583346:CKR_RS06185
uniprot id: B9E127
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

583346:CKR RS08865
gene id: 583346:CKR_RS08865
uniprot id: B9E2K0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

583346:CKR RS04335
gene id: 583346:CKR_RS04335
uniprot id: B9E021
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

583346:CKR RS13705
gene id: 583346:CKR_RS13705
uniprot id: B9E553
names: Similarity
messages: Belongs to the UPF0751 family.

583346:CKR RS13115
gene id: 583346:CKR_RS13115
uniprot id: B9E4U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

583346:CKR RS05330
gene id: 583346:CKR_RS05330
uniprot id: B9E0L0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

583346:CKR RS06390
gene id: 583346:CKR_RS06390
uniprot id: B9E168
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

583346:CKR RS05810
gene id: 583346:CKR_RS05810
uniprot id: B9E0V3
names: Similarity
messages: Belongs to the peptidase S16 family.

583346:CKR RS16475
gene id: 583346:CKR_RS16475
uniprot id: B9DWM9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

583346:CKR RS03150
gene id: 583346:CKR_RS03150
uniprot id: B9DZE4
names: Similarity
messages: Belongs to the UPF0229 family.

583346:CKR RS09895
gene id: 583346:CKR_RS09895
uniprot id: B9E332
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

583346:CKR RS17850
gene id: 583346:CKR_RS17850
uniprot id: B9DXD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

583346:CKR RS15140
gene id: 583346:CKR_RS15140
uniprot id: B9E5W5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

583346:CKR RS10235
gene id: 583346:CKR_RS10235
uniprot id: B9E398
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

583346:CKR RS04640
gene id: 583346:CKR_RS04640
uniprot id: B9E081
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

583346:CKR RS00675
gene id: 583346:CKR_RS00675
uniprot id: B9DY39
names: Similarity
messages: Belongs to the ComB family.

583346:CKR RS04370
gene id: 583346:CKR_RS04370
uniprot id: B9E028
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583346:CKR RS03645
gene id: 583346:CKR_RS03645
uniprot id: B9DZN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

583346:CKR RS01140
gene id: 583346:CKR_RS01140
uniprot id: B9DYB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

583346:CKR RS15950
gene id: 583346:CKR_RS15950
uniprot id: B9E6A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

583346:CKR RS16705
gene id: 583346:CKR_RS16705
uniprot id: B9DWS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

583346:CKR RS05680
gene id: 583346:CKR_RS05680
uniprot id: B9E0S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

583346:CKR RS05870
gene id: 583346:CKR_RS05870
uniprot id: B9E0W5
names: Similarity
messages: Belongs to the UPF0749 family.

583346:CKR RS02925
gene id: 583346:CKR_RS02925
uniprot id: B9DZ99
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS07530
gene id: 583346:CKR_RS07530
uniprot id: B9E1U4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS06660
gene id: 583346:CKR_RS06660
uniprot id: B9E1C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

583346:CKR RS10085
gene id: 583346:CKR_RS10085
uniprot id: B9E368
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS10270
gene id: 583346:CKR_RS10270
uniprot id: B9E3A5
names: Similarity
messages: Belongs to the UPF0047 family.

583346:CKR RS12840
gene id: 583346:CKR_RS12840
uniprot id: B9E4P2
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS15025
gene id: 583346:CKR_RS15025
uniprot id: B9E5U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

583346:CKR RS10980
gene id: 583346:CKR_RS10980
uniprot id: B9E3N6
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

583346:CKR RS13750
gene id: 583346:CKR_RS13750
uniprot id: B9E562
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

583346:CKR RS14045
gene id: 583346:CKR_RS14045
uniprot id: B9DXU9
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

583346:CKR RS04020
gene id: 583346:CKR_RS04020
uniprot id: B9DZV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

583346:CKR RS08900
gene id: 583346:CKR_RS08900
uniprot id: B9E2K7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

583346:CKR RS08870
gene id: 583346:CKR_RS08870
uniprot id: B9E2K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

583346:CKR RS09650
gene id: 583346:CKR_RS09650
uniprot id: B9E2Y4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

583346:CKR RS09690
gene id: 583346:CKR_RS09690
uniprot id: B9E2Z2
names: Similarity
messages: Belongs to the YoeB family.

583346:CKR RS06250
gene id: 583346:CKR_RS06250
uniprot id: B9E140
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

583346:CKR RS03465
gene id: 583346:CKR_RS03465
uniprot id: B9DZK2
names: Similarity
messages: Belongs to the threonine synthase family.

583346:CKR RS16545
gene id: 583346:CKR_RS16545
uniprot id: B9DWP2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

583346:CKR RS04605
gene id: 583346:CKR_RS04605
uniprot id: B9E074
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

583346:CKR RS03565
gene id: 583346:CKR_RS03565
uniprot id: B9DZM2
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

583346:CKR RS01840
gene id: 583346:CKR_RS01840
uniprot id: B9DYP8
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

583346:CKR RS15820
gene id: 583346:CKR_RS15820
uniprot id: B9E683
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

583346:CKR RS10010
gene id: 583346:CKR_RS10010
uniprot id: B9E355
names: Similarity
messages: Belongs to the RecJ family.

583346:CKR RS04425
gene id: 583346:CKR_RS04425
uniprot id: B9E039
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

583346:CKR RS02155
gene id: 583346:CKR_RS02155
uniprot id: B9DYV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

583346:CKR RS07610
gene id: 583346:CKR_RS07610
uniprot id: B9E1W2
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS01220
gene id: 583346:CKR_RS01220
uniprot id: B9DYD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

583346:CKR RS03100
gene id: 583346:CKR_RS03100
uniprot id: B9DZD4
names: Similarity
messages: Belongs to the UPF0251 family.

583346:CKR RS02765
gene id: 583346:CKR_RS02765
uniprot id: B9DZ72
names: Similarity
messages: Belongs to the type IA topoisomerase family.

583346:CKR RS07120
gene id: 583346:CKR_RS07120
uniprot id: B9E1L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

583346:CKR RS02230
gene id: 583346:CKR_RS02230
uniprot id: B9DYX1
names: Similarity
messages: Belongs to the UPF0045 family.

583346:CKR RS03210
gene id: 583346:CKR_RS03210
uniprot id: B9DZF5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS16115
gene id: 583346:CKR_RS16115
uniprot id: B9E6E0
names: Similarity
messages: Belongs to the CinA family.

583346:CKR RS06210
gene id: 583346:CKR_RS06210
uniprot id: B9E132
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

583346:CKR RS00715
gene id: 583346:CKR_RS00715
uniprot id: B9DY47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

583346:CKR RS18575
gene id: 583346:CKR_RS18575
uniprot id: B9DXQ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

583346:CKR RS06980
gene id: 583346:CKR_RS06980
uniprot id: B9E1I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

583346:CKR RS16550
gene id: 583346:CKR_RS16550
uniprot id: B9DWP3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

583346:CKR RS10625
gene id: 583346:CKR_RS10625
uniprot id: B9E3H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

583346:CKR RS00360
gene id: 583346:CKR_RS00360
uniprot id: B9DXY2
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS13195
gene id: 583346:CKR_RS13195
uniprot id: B9E4W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

583346:CKR RS04435
gene id: 583346:CKR_RS04435
uniprot id: B9E041
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

583346:CKR RS01090
gene id: 583346:CKR_RS01090
uniprot id: B9DYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

583346:CKR RS06550
gene id: 583346:CKR_RS06550
uniprot id: B9E1A0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

583346:CKR RS07490
gene id: 583346:CKR_RS07490
uniprot id: B9E1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

583346:CKR RS01130
gene id: 583346:CKR_RS01130
uniprot id: B9DYB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

583346:CKR RS05910
gene id: 583346:CKR_RS05910
uniprot id: B9E0X3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

583346:CKR RS10070
gene id: 583346:CKR_RS10070
uniprot id: B9E365
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

583346:CKR RS01120
gene id: 583346:CKR_RS01120
uniprot id: B9DYB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

583346:CKR RS04975
gene id: 583346:CKR_RS04975
uniprot id: B9E0D9
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

583346:CKR RS01100
gene id: 583346:CKR_RS01100
uniprot id: B9DYA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

583346:CKR RS11580
gene id: 583346:CKR_RS11580
uniprot id: B9E404
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS07775
gene id: 583346:CKR_RS07775
uniprot id: B9E1Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

583346:CKR RS16380
gene id: 583346:CKR_RS16380
uniprot id: B9DWL1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

583346:CKR RS03425
gene id: 583346:CKR_RS03425
uniprot id: B9DZJ4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

583346:CKR RS07010
gene id: 583346:CKR_RS07010
uniprot id: B9E1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

583346:CKR RS04155
gene id: 583346:CKR_RS04155
uniprot id: B9DZY5
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

583346:CKR RS09945
gene id: 583346:CKR_RS09945
uniprot id: B9E342
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS11480
gene id: 583346:CKR_RS11480
uniprot id: B9E3Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

583346:CKR RS15890
gene id: 583346:CKR_RS15890
uniprot id: B9E697
names: Similarity
messages: Belongs to the UDPGP type 2 family.

583346:CKR RS11485
gene id: 583346:CKR_RS11485
uniprot id: B9E3Y6
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS02135
gene id: 583346:CKR_RS02135
uniprot id: B9DYV2
names: Similarity
messages: Belongs to the P(II) protein family.

583346:CKR RS08795
gene id: 583346:CKR_RS08795
uniprot id: B9E2I6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS03915
gene id: 583346:CKR_RS03915
uniprot id: B9DZT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

583346:CKR RS01205
gene id: 583346:CKR_RS01205
uniprot id: B9DYC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

583346:CKR RS15960
gene id: 583346:CKR_RS15960
uniprot id: B9E6B1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

583346:CKR RS08420
gene id: 583346:CKR_RS08420
uniprot id: B9E2B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

583346:CKR RS05760
gene id: 583346:CKR_RS05760
uniprot id: B9E0U3
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

583346:CKR RS16200
gene id: 583346:CKR_RS16200
uniprot id: B9DWI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

583346:CKR RS18685
gene id: 583346:CKR_RS18685
uniprot id: B9DXS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

583346:CKR RS05450
gene id: 583346:CKR_RS05450
uniprot id: B9E0N2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

583346:CKR RS18025
gene id: 583346:CKR_RS18025
uniprot id: B9DXG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

583346:CKR RS01835
gene id: 583346:CKR_RS01835
uniprot id: B9DYP7
names: Function
names: Subunit
messages: Hexamer of two alpha, two beta, and two delta chains.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.

583346:CKR RS15735
gene id: 583346:CKR_RS15735
uniprot id: B9E666
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

583346:CKR RS08595
gene id: 583346:CKR_RS08595
uniprot id: B9E2E7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-100 inactivates the nitrogenase reductase and regulates nitrogenase activity.

583346:CKR RS06410
gene id: 583346:CKR_RS06410
uniprot id: B9E172
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

583346:CKR RS00885
gene id: 583346:CKR_RS00885
uniprot id: B9DY74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS00875
gene id: 583346:CKR_RS00875
uniprot id: B9DY73
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

583346:CKR RS18145
gene id: 583346:CKR_RS18145
uniprot id: B9DXI3
names: Similarity
messages: Belongs to the SfsA family.

583346:CKR RS01070
gene id: 583346:CKR_RS01070
uniprot id: B9DYA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

583346:CKR RS05880
gene id: 583346:CKR_RS05880
uniprot id: B9E0W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

583346:CKR RS17505
gene id: 583346:CKR_RS17505
uniprot id: B9DX67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

583346:CKR RS15830
gene id: 583346:CKR_RS15830
uniprot id: B9E685
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

583346:CKR RS01745
gene id: 583346:CKR_RS01745
uniprot id: B9DYM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS17905
gene id: 583346:CKR_RS17905
uniprot id: B9DXE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

583346:CKR RS06945
gene id: 583346:CKR_RS06945
uniprot id: B9E1I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

583346:CKR RS01165
gene id: 583346:CKR_RS01165
uniprot id: B9DYC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

583346:CKR RS06680
gene id: 583346:CKR_RS06680
uniprot id: B9E1C6
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS12690
gene id: 583346:CKR_RS12690
uniprot id: B9E4L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

583346:CKR RS06320
gene id: 583346:CKR_RS06320
uniprot id: B9E154
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

583346:CKR RS01040
gene id: 583346:CKR_RS01040
uniprot id: B9DY96
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

583346:CKR RS04350
gene id: 583346:CKR_RS04350
uniprot id: B9E024
names: Similarity
messages: Belongs to the RutC family.

583346:CKR RS15765
gene id: 583346:CKR_RS15765
uniprot id: B9E672
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS07305
gene id: 583346:CKR_RS07305
uniprot id: B9E1Q2
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS09310
gene id: 583346:CKR_RS09310
uniprot id: B9E2S7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

583346:CKR RS05475
gene id: 583346:CKR_RS05475
uniprot id: B9E0N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

583346:CKR RS10355
gene id: 583346:CKR_RS10355
uniprot id: B9E3C1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS17960
gene id: 583346:CKR_RS17960
uniprot id: B9DXF4
names: Similarity
messages: Belongs to the peptidase C40 family.

583346:CKR RS14330
gene id: 583346:CKR_RS14330
uniprot id: B9E5G2
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS14345
gene id: 583346:CKR_RS14345
uniprot id: B9E5G5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS14995
gene id: 583346:CKR_RS14995
uniprot id: B9E5U1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

583346:CKR RS10810
gene id: 583346:CKR_RS10810
uniprot id: B9E3K3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

583346:CKR RS15015
gene id: 583346:CKR_RS15015
uniprot id: B9E5U5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

583346:CKR RS15760
gene id: 583346:CKR_RS15760
uniprot id: B9E671
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

583346:CKR RS12650
gene id: 583346:CKR_RS12650
uniprot id: B9E4K7
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS05730
gene id: 583346:CKR_RS05730
uniprot id: B9E0T7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

583346:CKR RS04655
gene id: 583346:CKR_RS04655
uniprot id: B9E084
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

583346:CKR RS05875
gene id: 583346:CKR_RS05875
uniprot id: B9E0W6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

583346:CKR RS07020
gene id: 583346:CKR_RS07020
uniprot id: B9E1J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

583346:CKR RS09805
gene id: 583346:CKR_RS09805
uniprot id: B9E314
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

583346:CKR RS05320
gene id: 583346:CKR_RS05320
uniprot id: B9E0K8
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS12740
gene id: 583346:CKR_RS12740
uniprot id: B9E4M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

583346:CKR RS12870
gene id: 583346:CKR_RS12870
uniprot id: B9E4P8
names: Similarity
messages: Belongs to the peptidase S41A family.

583346:CKR RS15970
gene id: 583346:CKR_RS15970
uniprot id: B9E6B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

583346:CKR RS03775
gene id: 583346:CKR_RS03775
uniprot id: B9DZR3
names: Similarity
messages: Belongs to the glutamate synthase family.

583346:CKR RS18580
gene id: 583346:CKR_RS18580
uniprot id: B9DXQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

583346:CKR RS01190
gene id: 583346:CKR_RS01190
uniprot id: B9DYC6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

583346:CKR RS05845
gene id: 583346:CKR_RS05845
uniprot id: B9E0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

583346:CKR RS09505
gene id: 583346:CKR_RS09505
uniprot id: B9E2V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

583346:CKR RS15135
gene id: 583346:CKR_RS15135
uniprot id: B9E5W4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

583346:CKR RS06750
gene id: 583346:CKR_RS06750
uniprot id: B9E1E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

583346:CKR RS18675
gene id: 583346:CKR_RS18675
uniprot id: B9DXS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

583346:CKR RS01645
gene id: 583346:CKR_RS01645
uniprot id: B9DYL1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

583346:CKR RS04835
gene id: 583346:CKR_RS04835
uniprot id: B9E0B1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

583346:CKR RS06690
gene id: 583346:CKR_RS06690
uniprot id: B9E1C8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

583346:CKR RS04275
gene id: 583346:CKR_RS04275
uniprot id: B9E009
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

583346:CKR RS17280
gene id: 583346:CKR_RS17280
uniprot id: B9DX27
names: Similarity
messages: Belongs to the UPF0251 family.

583346:CKR RS17545
gene id: 583346:CKR_RS17545
uniprot id: B9DX75
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

583346:CKR RS10780
gene id: 583346:CKR_RS10780
uniprot id: B9E3J7
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS16455
gene id: 583346:CKR_RS16455
uniprot id: B9DWM5
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS13225
gene id: 583346:CKR_RS13225
uniprot id: B9E4W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

583346:CKR RS08025
gene id: 583346:CKR_RS08025
uniprot id: B9E242
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

583346:CKR RS01780
gene id: 583346:CKR_RS01780
uniprot id: B9DYN6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

583346:CKR RS16880
gene id: 583346:CKR_RS16880
uniprot id: B9DWV1
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

583346:CKR RS03560
gene id: 583346:CKR_RS03560
uniprot id: B9DZM1
names: Similarity
messages: Belongs to the CobH/CbiC family.

583346:CKR RS12905
gene id: 583346:CKR_RS12905
uniprot id: B9E4Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

583346:CKR RS15065
gene id: 583346:CKR_RS15065
uniprot id: B9E5V5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

583346:CKR RS01495
gene id: 583346:CKR_RS01495
uniprot id: B9DYI0
names: Similarity
messages: Belongs to the class-I fumarase family.

583346:CKR RS11320
gene id: 583346:CKR_RS11320
uniprot id: B9E3V3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

583346:CKR RS17535
gene id: 583346:CKR_RS17535
uniprot id: B9DX73
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS12220
gene id: 583346:CKR_RS12220
uniprot id: B9E4C9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

583346:CKR RS10970
gene id: 583346:CKR_RS10970
uniprot id: B9E3N4
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

583346:CKR RS17115
gene id: 583346:CKR_RS17115
uniprot id: B9DWZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

583346:CKR RS03225
gene id: 583346:CKR_RS03225
uniprot id: B9DZF8
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS11460
gene id: 583346:CKR_RS11460
uniprot id: B9E3Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

583346:CKR RS03550
gene id: 583346:CKR_RS03550
uniprot id: B9DZL9
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

583346:CKR RS11275
gene id: 583346:CKR_RS11275
uniprot id: B9E3U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

583346:CKR RS05335
gene id: 583346:CKR_RS05335
uniprot id: B9E0L1
names: Similarity
messages: Belongs to the DtxR/MntR family.

583346:CKR RS08165
gene id: 583346:CKR_RS08165
uniprot id: B9E268
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS06605
gene id: 583346:CKR_RS06605
uniprot id: B9E1B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

583346:CKR RS00760
gene id: 583346:CKR_RS00760
uniprot id: B9DY56
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS16130
gene id: 583346:CKR_RS16130
uniprot id: B9DWH5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

583346:CKR RS11240
gene id: 583346:CKR_RS11240
uniprot id: B9E3T7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

583346:CKR RS00605
gene id: 583346:CKR_RS00605
uniprot id: B9DY24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

583346:CKR RS04085
gene id: 583346:CKR_RS04085
uniprot id: B9DZX3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

583346:CKR RS04990
gene id: 583346:CKR_RS04990
uniprot id: B9E0E2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

583346:CKR RS08720
gene id: 583346:CKR_RS08720
uniprot id: B9E2H2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

583346:CKR RS16170
gene id: 583346:CKR_RS16170
uniprot id: B9DWI3
names: Similarity
messages: Belongs to the EutP/PduV family.

583346:CKR RS01175
gene id: 583346:CKR_RS01175
uniprot id: B9DYC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

583346:CKR RS03870
gene id: 583346:CKR_RS03870
uniprot id: B9DZT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

583346:CKR RS02290
gene id: 583346:CKR_RS02290
uniprot id: B9DYY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

583346:CKR RS05755
gene id: 583346:CKR_RS05755
uniprot id: B9E0U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

583346:CKR RS17665
gene id: 583346:CKR_RS17665
uniprot id: B9DX98
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

583346:CKR RS16075
gene id: 583346:CKR_RS16075
uniprot id: B9E6D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

583346:CKR RS10420
gene id: 583346:CKR_RS10420
uniprot id: B9E3D4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

583346:CKR RS11665
gene id: 583346:CKR_RS11665
uniprot id: B9E420
names: Similarity
messages: Belongs to the CFA/CMAS family.

583346:CKR RS14850
gene id: 583346:CKR_RS14850
uniprot id: B9E5R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

583346:CKR RS07255
gene id: 583346:CKR_RS07255
uniprot id: B9E1P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

583346:CKR RS04445
gene id: 583346:CKR_RS04445
uniprot id: B9E043
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

583346:CKR RS02840
gene id: 583346:CKR_RS02840
uniprot id: B9DZ85
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS04885
gene id: 583346:CKR_RS04885
uniprot id: B9E0C1
names: Similarity
messages: Belongs to the CvfB family.

583346:CKR RS10340
gene id: 583346:CKR_RS10340
uniprot id: B9E3B8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

583346:CKR RS13340
gene id: 583346:CKR_RS13340
uniprot id: B9E4Y8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

583346:CKR RS07970
gene id: 583346:CKR_RS07970
uniprot id: B9E231
names: Similarity
messages: Belongs to the glutamate synthase family.

583346:CKR RS13460
gene id: 583346:CKR_RS13460
uniprot id: B9E510
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

583346:CKR RS01105
gene id: 583346:CKR_RS01105
uniprot id: B9DYA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

583346:CKR RS16515
gene id: 583346:CKR_RS16515
uniprot id: B9DWN6
names: Similarity
messages: Belongs to the UPF0178 family.

583346:CKR RS04890
gene id: 583346:CKR_RS04890
uniprot id: B9E0C2
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

583346:CKR RS15870
gene id: 583346:CKR_RS15870
uniprot id: B9E693
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

583346:CKR RS11145
gene id: 583346:CKR_RS11145
uniprot id: B9E3R8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

583346:CKR RS03585
gene id: 583346:CKR_RS03585
uniprot id: B9DZM6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

583346:CKR RS03045
gene id: 583346:CKR_RS03045
uniprot id: B9DZC3
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS17595
gene id: 583346:CKR_RS17595
uniprot id: B9DX85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

583346:CKR RS02090
gene id: 583346:CKR_RS02090
uniprot id: B9DYU3
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

583346:CKR RS13425
gene id: 583346:CKR_RS13425
uniprot id: B9E503
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

583346:CKR RS14040
gene id: 583346:CKR_RS14040
uniprot id: B9E5A9
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS01250
gene id: 583346:CKR_RS01250
uniprot id: B9DYD8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

583346:CKR RS11520
gene id: 583346:CKR_RS11520
uniprot id: B9E3Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

583346:CKR RS15165
gene id: 583346:CKR_RS15165
uniprot id: B9E5X0
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

583346:CKR RS13990
gene id: 583346:CKR_RS13990
uniprot id: B9E599
names: Subcellular Location Annotation
messages: Cytoplasm

583346:CKR RS07720
gene id: 583346:CKR_RS07720
uniprot id: B9E1Y4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

583346:CKR RS04420
gene id: 583346:CKR_RS04420
uniprot id: B9E038
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

583346:CKR RS17710
gene id: 583346:CKR_RS17710
uniprot id: B9DXA7
names: Subcellular Location Annotation
messages: Membrane

583346:CKR RS10465
gene id: 583346:CKR_RS10465
uniprot id: B9E3E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

583346:CKR RS16385
gene id: 583346:CKR_RS16385
uniprot id: B9DWL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

583346:CKR RS06135
gene id: 583346:CKR_RS06135
uniprot id: B9E117
names: Similarity
messages: Belongs to the HepT RNase toxin family.

583346:CKR RS12585
gene id: 583346:CKR_RS12585
uniprot id: B9E4J4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

583346:CKR RS16675
gene id: 583346:CKR_RS16675
uniprot id: B9DWR6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS10350
gene id: 583346:CKR_RS10350
uniprot id: B9E3C0
names: Similarity
messages: Belongs to the EamA transporter family.

583346:CKR RS16215
gene id: 583346:CKR_RS16215
uniprot id: B9DWJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

583346:CKR RS07375
gene id: 583346:CKR_RS07375
uniprot id: B9E1R5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

583346:CKR RS08455
gene id: 583346:CKR_RS08455
uniprot id: B9E2C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

583346:CKR RS01920
gene id: 583346:CKR_RS01920
uniprot id: B9DYR4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

583346:CKR RS14560
gene id: 583346:CKR_RS14560
uniprot id: B9E5K8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

583346:CKR RS16230
gene id: 583346:CKR_RS16230
uniprot id: B9DWJ5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

583346:CKR RS04715
gene id: 583346:CKR_RS04715
uniprot id: B9E091
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

583346:CKR RS06310
gene id: 583346:CKR_RS06310
uniprot id: B9E152
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

583346:CKR RS10345
gene id: 583346:CKR_RS10345
uniprot id: B9E3B9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

583346:CKR RS06930
gene id: 583346:CKR_RS06930
uniprot id: B9E1H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

583346:CKR RS08170
gene id: 583346:CKR_RS08170
uniprot id: B9E269
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

583346:CKR RS01610
gene id: 583346:CKR_RS01610
uniprot id: B9DYK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

583346:CKR RS16415
gene id: 583346:CKR_RS16415
uniprot id: B9DWL7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

583346:CKR RS10955
gene id: 583346:CKR_RS10955
uniprot id: B9E3N1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

583346:CKR RS16580
gene id: 583346:CKR_RS16580
uniprot id: B9DWP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane