582899:HDEN RS06220
gene id: 582899:HDEN_RS06220
uniprot id: D8JWG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

582899:HDEN RS17045
gene id: 582899:HDEN_RS17045
uniprot id: D8JY30
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

582899:HDEN RS08415
gene id: 582899:HDEN_RS08415
uniprot id: D8JYR7
names: Similarity
messages: Belongs to the fabD family.

582899:HDEN RS02240
gene id: 582899:HDEN_RS02240
uniprot id: D8JS18
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

582899:HDEN RS12785
gene id: 582899:HDEN_RS12785
uniprot id: D8JT69
names: Similarity
messages: Belongs to the GARS family.

582899:HDEN RS08500
gene id: 582899:HDEN_RS08500
uniprot id: D8JYT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

582899:HDEN RS17270
gene id: 582899:HDEN_RS17270
uniprot id: D8JY73
names: Similarity
messages: Belongs to the PhoH family.

582899:HDEN RS15045
gene id: 582899:HDEN_RS15045
uniprot id: D8JVI5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

582899:HDEN RS12395
gene id: 582899:HDEN_RS12395
uniprot id: D8JSL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

582899:HDEN RS07995
gene id: 582899:HDEN_RS07995
uniprot id: D8JYI4
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

582899:HDEN RS02710
gene id: 582899:HDEN_RS02710
uniprot id: D8JSB5
names: Similarity
messages: Belongs to the PqqA family.

582899:HDEN RS00980
gene id: 582899:HDEN_RS00980
uniprot id: D8JQB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS15110
gene id: 582899:HDEN_RS15110
uniprot id: D8JVJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

582899:HDEN RS06200
gene id: 582899:HDEN_RS06200
uniprot id: D8JWF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

582899:HDEN RS16810
gene id: 582899:HDEN_RS16810
uniprot id: D8JXL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

582899:HDEN RS03610
gene id: 582899:HDEN_RS03610
uniprot id: D8JTJ8
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

582899:HDEN RS16250
gene id: 582899:HDEN_RS16250
uniprot id: D8JWX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

582899:HDEN RS03395
gene id: 582899:HDEN_RS03395
uniprot id: D8JT33
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

582899:HDEN RS01310
gene id: 582899:HDEN_RS01310
uniprot id: D8JQU5
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

582899:HDEN RS14140
gene id: 582899:HDEN_RS14140
uniprot id: D8JUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

582899:HDEN RS07315
gene id: 582899:HDEN_RS07315
uniprot id: D8JXT4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

582899:HDEN RS10700
gene id: 582899:HDEN_RS10700
uniprot id: D8JQL3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS05130
gene id: 582899:HDEN_RS05130
uniprot id: D8JV37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

582899:HDEN RS02020
gene id: 582899:HDEN_RS02020
uniprot id: D8JRK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

582899:HDEN RS12870
gene id: 582899:HDEN_RS12870
uniprot id: D8JT87
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

582899:HDEN RS04680
gene id: 582899:HDEN_RS04680
uniprot id: D8JUU8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

582899:HDEN RS02650
gene id: 582899:HDEN_RS02650
uniprot id: D8JSA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

582899:HDEN RS08240
gene id: 582899:HDEN_RS08240
uniprot id: D8JYN2
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

582899:HDEN RS09670
gene id: 582899:HDEN_RS09670
uniprot id: D8JPM8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

582899:HDEN RS16680
gene id: 582899:HDEN_RS16680
uniprot id: D8JXI4
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS13095
gene id: 582899:HDEN_RS13095
uniprot id: D8JTD0
names: Similarity
messages: Belongs to the glutamate synthase family.

582899:HDEN RS07875
gene id: 582899:HDEN_RS07875
uniprot id: D8JYG0
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS11965
gene id: 582899:HDEN_RS11965
uniprot id: D8JS04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

582899:HDEN RS12650
gene id: 582899:HDEN_RS12650
uniprot id: D8JT43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

582899:HDEN RS02625
gene id: 582899:HDEN_RS02625
uniprot id: D8JS97
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

582899:HDEN RS02135
gene id: 582899:HDEN_RS02135
uniprot id: D8JRM8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

582899:HDEN RS13380
gene id: 582899:HDEN_RS13380
uniprot id: D8JTV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

582899:HDEN RS15575
gene id: 582899:HDEN_RS15575
uniprot id: D8JW66
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

582899:HDEN RS13970
gene id: 582899:HDEN_RS13970
uniprot id: D8JUJ3
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS15600
gene id: 582899:HDEN_RS15600
uniprot id: D8JW71
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS16425
gene id: 582899:HDEN_RS16425
uniprot id: D8JXD3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS16050
gene id: 582899:HDEN_RS16050
uniprot id: D8JWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

582899:HDEN RS13480
gene id: 582899:HDEN_RS13480
uniprot id: D8JTX5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

582899:HDEN RS14225
gene id: 582899:HDEN_RS14225
uniprot id: D8JUP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

582899:HDEN RS04990
gene id: 582899:HDEN_RS04990
uniprot id: D8JV09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

582899:HDEN RS03560
gene id: 582899:HDEN_RS03560
uniprot id: D8JTI8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

582899:HDEN RS11580
gene id: 582899:HDEN_RS11580
uniprot id: D8JRS5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

582899:HDEN RS08875
gene id: 582899:HDEN_RS08875
uniprot id: D8JZ09
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

582899:HDEN RS00960
gene id: 582899:HDEN_RS00960
uniprot id: D8JQA6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

582899:HDEN RS14035
gene id: 582899:HDEN_RS14035
uniprot id: D8JUK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

582899:HDEN RS16545
gene id: 582899:HDEN_RS16545
uniprot id: D8JXF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

582899:HDEN RS06955
gene id: 582899:HDEN_RS06955
uniprot id: D8JX86
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

582899:HDEN RS12405
gene id: 582899:HDEN_RS12405
uniprot id: D8JSL7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

582899:HDEN RS17420
gene id: 582899:HDEN_RS17420
uniprot id: D8JYA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

582899:HDEN RS16570
gene id: 582899:HDEN_RS16570
uniprot id: D8JXG2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

582899:HDEN RS09350
gene id: 582899:HDEN_RS09350
uniprot id: D8JZA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

582899:HDEN RS12680
gene id: 582899:HDEN_RS12680
uniprot id: D8JT49
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

582899:HDEN RS16480
gene id: 582899:HDEN_RS16480
uniprot id: D8JXE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

582899:HDEN RS12385
gene id: 582899:HDEN_RS12385
uniprot id: D8JSL3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

582899:HDEN RS00895
gene id: 582899:HDEN_RS00895
uniprot id: D8JQ94
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

582899:HDEN RS15475
gene id: 582899:HDEN_RS15475
uniprot id: D8JW47
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS10630
gene id: 582899:HDEN_RS10630
uniprot id: D8JQK0
names: Similarity
messages: Belongs to the GSP E family.

582899:HDEN RS16635
gene id: 582899:HDEN_RS16635
uniprot id: D8JXH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

582899:HDEN RS06245
gene id: 582899:HDEN_RS06245
uniprot id: D8JWG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

582899:HDEN RS15935
gene id: 582899:HDEN_RS15935
uniprot id: D8JWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

582899:HDEN RS16025
gene id: 582899:HDEN_RS16025
uniprot id: D8JWS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

582899:HDEN RS17110
gene id: 582899:HDEN_RS17110
uniprot id: D8JY42
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS16800
gene id: 582899:HDEN_RS16800
uniprot id: D8JXK8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

582899:HDEN RS05385
gene id: 582899:HDEN_RS05385
uniprot id: D8JVL2
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

582899:HDEN RS15245
gene id: 582899:HDEN_RS15245
uniprot id: D8JW00
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS02610
gene id: 582899:HDEN_RS02610
uniprot id: D8JS93
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

582899:HDEN RS12350
gene id: 582899:HDEN_RS12350
uniprot id: D8JSK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

582899:HDEN RS11155
gene id: 582899:HDEN_RS11155
uniprot id: D8JR76
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

582899:HDEN RS00970
gene id: 582899:HDEN_RS00970
uniprot id: D8JQA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

582899:HDEN RS16670
gene id: 582899:HDEN_RS16670
uniprot id: D8JXI2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

582899:HDEN RS16020
gene id: 582899:HDEN_RS16020
uniprot id: D8JWS4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

582899:HDEN RS09390
gene id: 582899:HDEN_RS09390
uniprot id: D8JZA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

582899:HDEN RS10020
gene id: 582899:HDEN_RS10020
uniprot id: D8JPU8
names: Similarity
messages: Belongs to the universal stress protein A family.

582899:HDEN RS14350
gene id: 582899:HDEN_RS14350
uniprot id: D8JUR7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS10705
gene id: 582899:HDEN_RS10705
uniprot id: D8JQL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

582899:HDEN RS09245
gene id: 582899:HDEN_RS09245
uniprot id: D8JZ81
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS09160
gene id: 582899:HDEN_RS09160
uniprot id: D8JZ66
names: Similarity
messages: Belongs to the phosphohexose mutase family.

582899:HDEN RS09425
gene id: 582899:HDEN_RS09425
uniprot id: D8JZB5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS04730
gene id: 582899:HDEN_RS04730
uniprot id: D8JUV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

582899:HDEN RS08350
gene id: 582899:HDEN_RS08350
uniprot id: D8JYQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

582899:HDEN RS16450
gene id: 582899:HDEN_RS16450
uniprot id: D8JXD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

582899:HDEN RS02470
gene id: 582899:HDEN_RS02470
uniprot id: D8JS65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

582899:HDEN RS05065
gene id: 582899:HDEN_RS05065
uniprot id: D8JV24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

582899:HDEN RS00875
gene id: 582899:HDEN_RS00875
uniprot id: D8JQ90
names: Similarity
messages: Belongs to the polysaccharide synthase family.

582899:HDEN RS10935
gene id: 582899:HDEN_RS10935
uniprot id: D8JR32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS12115
gene id: 582899:HDEN_RS12115
uniprot id: D8JSF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

582899:HDEN RS12380
gene id: 582899:HDEN_RS12380
uniprot id: D8JSL2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

582899:HDEN RS17350
gene id: 582899:HDEN_RS17350
uniprot id: D8JY89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

582899:HDEN RS15400
gene id: 582899:HDEN_RS15400
uniprot id: D8JW31
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

582899:HDEN RS11185
gene id: 582899:HDEN_RS11185
uniprot id: D8JR82
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS07380
gene id: 582899:HDEN_RS07380
uniprot id: D8JXU8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

582899:HDEN RS01000
gene id: 582899:HDEN_RS01000
uniprot id: D8JQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

582899:HDEN RS15210
gene id: 582899:HDEN_RS15210
uniprot id: D8JVZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

582899:HDEN RS07440
gene id: 582899:HDEN_RS07440
uniprot id: D8JXW0
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS13645
gene id: 582899:HDEN_RS13645
uniprot id: D8JU08
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

582899:HDEN RS04015
gene id: 582899:HDEN_RS04015
uniprot id: D8JTS5
names: Similarity
messages: Belongs to the UPF0111 family.

582899:HDEN RS17140
gene id: 582899:HDEN_RS17140
uniprot id: D8JY48
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS10005
gene id: 582899:HDEN_RS10005
uniprot id: D8JPU5
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

582899:HDEN RS06935
gene id: 582899:HDEN_RS06935
uniprot id: D8JX82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

582899:HDEN RS12570
gene id: 582899:HDEN_RS12570
uniprot id: D8JSQ1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

582899:HDEN RS05035
gene id: 582899:HDEN_RS05035
uniprot id: D8JV18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

582899:HDEN RS05705
gene id: 582899:HDEN_RS05705
uniprot id: D8JVS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

582899:HDEN RS04810
gene id: 582899:HDEN_RS04810
uniprot id: D8JUX5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

582899:HDEN RS09860
gene id: 582899:HDEN_RS09860
uniprot id: D8JPR7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

582899:HDEN RS17285
gene id: 582899:HDEN_RS17285
uniprot id: D8JY76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS01770
gene id: 582899:HDEN_RS01770
uniprot id: D8JRF7
names: Subcellular Location Annotation
messages: Cytoplasm

582899:HDEN RS01530
gene id: 582899:HDEN_RS01530
uniprot id: D8JQZ0
names: Similarity
messages: Belongs to the peptidase A24 family.

582899:HDEN RS16885
gene id: 582899:HDEN_RS16885
uniprot id: D8JXM5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

582899:HDEN RS17155
gene id: 582899:HDEN_RS17155
uniprot id: D8JY51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

582899:HDEN RS12030
gene id: 582899:HDEN_RS12030
uniprot id: D8JSE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

582899:HDEN RS08845
gene id: 582899:HDEN_RS08845
uniprot id: D8JZ03
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

582899:HDEN RS06845
gene id: 582899:HDEN_RS06845
uniprot id: D8JX64
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

582899:HDEN RS02865
gene id: 582899:HDEN_RS02865
uniprot id: D8JSS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

582899:HDEN RS17470
gene id: 582899:HDEN_RS17470
uniprot id: D8JYB2
names: Similarity
messages: Belongs to the aspartokinase family.

582899:HDEN RS09400
gene id: 582899:HDEN_RS09400
uniprot id: D8JZB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

582899:HDEN RS11050
gene id: 582899:HDEN_RS11050
uniprot id: D8JR54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

582899:HDEN RS08295
gene id: 582899:HDEN_RS08295
uniprot id: D8JYP3
names: Function
messages: Acts on leucine, isoleucine and valine.

582899:HDEN RS15625
gene id: 582899:HDEN_RS15625
uniprot id: D8JW75
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

582899:HDEN RS11875
gene id: 582899:HDEN_RS11875
uniprot id: D8JRY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

582899:HDEN RS02465
gene id: 582899:HDEN_RS02465
uniprot id: D8JS64
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

582899:HDEN RS12480
gene id: 582899:HDEN_RS12480
uniprot id: D8JSN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

582899:HDEN RS04075
gene id: 582899:HDEN_RS04075
uniprot id: D8JU58
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

582899:HDEN RS08560
gene id: 582899:HDEN_RS08560
uniprot id: D8JYU5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

582899:HDEN RS01335
gene id: 582899:HDEN_RS01335
uniprot id: D8JQV0
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

582899:HDEN RS01175
gene id: 582899:HDEN_RS01175
uniprot id: D8JQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

582899:HDEN RS11660
gene id: 582899:HDEN_RS11660
uniprot id: D8JRU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

582899:HDEN RS01425
gene id: 582899:HDEN_RS01425
uniprot id: D8JQW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

582899:HDEN RS01215
gene id: 582899:HDEN_RS01215
uniprot id: D8JQS5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS01990
gene id: 582899:HDEN_RS01990
uniprot id: D8JRK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

582899:HDEN RS11005
gene id: 582899:HDEN_RS11005
uniprot id: D8JR46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

582899:HDEN RS04970
gene id: 582899:HDEN_RS04970
uniprot id: D8JV05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

582899:HDEN RS15040
gene id: 582899:HDEN_RS15040
uniprot id: D8JVI4
names: Function
messages: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.

582899:HDEN RS18345
gene id: 582899:HDEN_RS18345
uniprot id: D8JYV2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

582899:HDEN RS12985
gene id: 582899:HDEN_RS12985
uniprot id: D8JTB0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

582899:HDEN RS07100
gene id: 582899:HDEN_RS07100
uniprot id: D8JXB5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

582899:HDEN RS02385
gene id: 582899:HDEN_RS02385
uniprot id: D8JS48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

582899:HDEN RS10655
gene id: 582899:HDEN_RS10655
uniprot id: D8JQK5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

582899:HDEN RS05395
gene id: 582899:HDEN_RS05395
uniprot id: D8JVL4
names: Similarity
messages: Belongs to the CutA family.

582899:HDEN RS07105
gene id: 582899:HDEN_RS07105
uniprot id: D8JXB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

582899:HDEN RS05090
gene id: 582899:HDEN_RS05090
uniprot id: D8JV29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

582899:HDEN RS13365
gene id: 582899:HDEN_RS13365
uniprot id: D8JTV4
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

582899:HDEN RS00975
gene id: 582899:HDEN_RS00975
uniprot id: D8JQA9
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS14210
gene id: 582899:HDEN_RS14210
uniprot id: D8JUP0
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

582899:HDEN RS03540
gene id: 582899:HDEN_RS03540
uniprot id: D8JTI4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

582899:HDEN RS07095
gene id: 582899:HDEN_RS07095
uniprot id: D8JXB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

582899:HDEN RS09535
gene id: 582899:HDEN_RS09535
uniprot id: D8JZD7
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

582899:HDEN RS01155
gene id: 582899:HDEN_RS01155
uniprot id: D8JQR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS09035
gene id: 582899:HDEN_RS09035
uniprot id: D8JZ40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

582899:HDEN RS03280
gene id: 582899:HDEN_RS03280
uniprot id: D8JT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

582899:HDEN RS09385
gene id: 582899:HDEN_RS09385
uniprot id: D8JZA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

582899:HDEN RS08405
gene id: 582899:HDEN_RS08405
uniprot id: D8JYR5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

582899:HDEN RS09045
gene id: 582899:HDEN_RS09045
uniprot id: D8JZ42
names: Similarity
messages: Belongs to the universal stress protein A family.

582899:HDEN RS04635
gene id: 582899:HDEN_RS04635
uniprot id: D8JUG5
names: Similarity
messages: Belongs to the SfsA family.

582899:HDEN RS16455
gene id: 582899:HDEN_RS16455
uniprot id: D8JXD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

582899:HDEN RS04765
gene id: 582899:HDEN_RS04765
uniprot id: D8JUW6
names: Similarity
messages: Belongs to the YkuD family.

582899:HDEN RS04965
gene id: 582899:HDEN_RS04965
uniprot id: D8JV04
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

582899:HDEN RS13315
gene id: 582899:HDEN_RS13315
uniprot id: D8JTU4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

582899:HDEN RS05365
gene id: 582899:HDEN_RS05365
uniprot id: D8JVK8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

582899:HDEN RS16555
gene id: 582899:HDEN_RS16555
uniprot id: D8JXF9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

582899:HDEN RS08150
gene id: 582899:HDEN_RS08150
uniprot id: D8JYL5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

582899:HDEN RS09950
gene id: 582899:HDEN_RS09950
uniprot id: D8JPT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

582899:HDEN RS00880
gene id: 582899:HDEN_RS00880
uniprot id: D8JQ91
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

582899:HDEN RS12295
gene id: 582899:HDEN_RS12295
uniprot id: D8JSJ4
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

582899:HDEN RS05110
gene id: 582899:HDEN_RS05110
uniprot id: D8JV33
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

582899:HDEN RS10255
gene id: 582899:HDEN_RS10255
uniprot id: D8JQC5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

582899:HDEN RS08555
gene id: 582899:HDEN_RS08555
uniprot id: D8JYU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

582899:HDEN RS15965
gene id: 582899:HDEN_RS15965
uniprot id: D8JWR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

582899:HDEN RS07240
gene id: 582899:HDEN_RS07240
uniprot id: D8JXR9
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

582899:HDEN RS06435
gene id: 582899:HDEN_RS06435
uniprot id: D8JWK4
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

582899:HDEN RS14500
gene id: 582899:HDEN_RS14500
uniprot id: D8JV74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

582899:HDEN RS08060
gene id: 582899:HDEN_RS08060
uniprot id: D8JYJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS02690
gene id: 582899:HDEN_RS02690
uniprot id: D8JSB1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS05615
gene id: 582899:HDEN_RS05615
uniprot id: D8JVQ7
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

582899:HDEN RS17220
gene id: 582899:HDEN_RS17220
uniprot id: D8JY63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

582899:HDEN RS08950
gene id: 582899:HDEN_RS08950
uniprot id: D8JZ24
names: Similarity
messages: Belongs to the UPF0047 family.

582899:HDEN RS10715
gene id: 582899:HDEN_RS10715
uniprot id: D8JQL6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

582899:HDEN RS03955
gene id: 582899:HDEN_RS03955
uniprot id: D8JTR3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

582899:HDEN RS10210
gene id: 582899:HDEN_RS10210
uniprot id: D8JPY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

582899:HDEN RS04400
gene id: 582899:HDEN_RS04400
uniprot id: D8JUC1
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

582899:HDEN RS16700
gene id: 582899:HDEN_RS16700
uniprot id: D8JXI8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

582899:HDEN RS04795
gene id: 582899:HDEN_RS04795
uniprot id: D8JUX2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

582899:HDEN RS15960
gene id: 582899:HDEN_RS15960
uniprot id: D8JWR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

582899:HDEN RS01185
gene id: 582899:HDEN_RS01185
uniprot id: D8JQR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

582899:HDEN RS03635
gene id: 582899:HDEN_RS03635
uniprot id: D8JTK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

582899:HDEN RS11410
gene id: 582899:HDEN_RS11410
uniprot id: D8JRC7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

582899:HDEN RS16365
gene id: 582899:HDEN_RS16365
uniprot id: D8JWZ4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

582899:HDEN RS03270
gene id: 582899:HDEN_RS03270
uniprot id: D8JT07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

582899:HDEN RS01180
gene id: 582899:HDEN_RS01180
uniprot id: D8JQR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

582899:HDEN RS09825
gene id: 582899:HDEN_RS09825
uniprot id: D8JPR0
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

582899:HDEN RS05085
gene id: 582899:HDEN_RS05085
uniprot id: D8JV28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

582899:HDEN RS17335
gene id: 582899:HDEN_RS17335
uniprot id: D8JY86
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

582899:HDEN RS12945
gene id: 582899:HDEN_RS12945
uniprot id: D8JTA2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

582899:HDEN RS06235
gene id: 582899:HDEN_RS06235
uniprot id: D8JWG4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS12885
gene id: 582899:HDEN_RS12885
uniprot id: D8JT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

582899:HDEN RS08905
gene id: 582899:HDEN_RS08905
uniprot id: D8JZ15
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS05810
gene id: 582899:HDEN_RS05810
uniprot id: D8JVV0
names: Function
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

582899:HDEN RS00860
gene id: 582899:HDEN_RS00860
uniprot id: D8JQ87
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS13425
gene id: 582899:HDEN_RS13425
uniprot id: D8JTW4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS05055
gene id: 582899:HDEN_RS05055
uniprot id: D8JV22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

582899:HDEN RS00885
gene id: 582899:HDEN_RS00885
uniprot id: D8JQ92
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

582899:HDEN RS15050
gene id: 582899:HDEN_RS15050
uniprot id: D8JVI6
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS01725
gene id: 582899:HDEN_RS01725
uniprot id: D8JRF0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

582899:HDEN RS16300
gene id: 582899:HDEN_RS16300
uniprot id: D8JWY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

582899:HDEN RS10350
gene id: 582899:HDEN_RS10350
uniprot id: D8JQE4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

582899:HDEN RS01935
gene id: 582899:HDEN_RS01935
uniprot id: D8JRJ0
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

582899:HDEN RS12335
gene id: 582899:HDEN_RS12335
uniprot id: D8JSK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

582899:HDEN RS07495
gene id: 582899:HDEN_RS07495
uniprot id: D8JXX2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

582899:HDEN RS16075
gene id: 582899:HDEN_RS16075
uniprot id: D8JWT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

582899:HDEN RS15945
gene id: 582899:HDEN_RS15945
uniprot id: D8JWQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

582899:HDEN RS11570
gene id: 582899:HDEN_RS11570
uniprot id: D8JRS3
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS12220
gene id: 582899:HDEN_RS12220
uniprot id: D8JSH9
names: Similarity
messages: Belongs to the peptidase C56 family.

582899:HDEN RS14285
gene id: 582899:HDEN_RS14285
uniprot id: D8JUQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

582899:HDEN RS17320
gene id: 582899:HDEN_RS17320
uniprot id: D8JY83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

582899:HDEN RS15645
gene id: 582899:HDEN_RS15645
uniprot id: D8JW79
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

582899:HDEN RS09915
gene id: 582899:HDEN_RS09915
uniprot id: D8JPS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

582899:HDEN RS08755
gene id: 582899:HDEN_RS08755
uniprot id: D8JYY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

582899:HDEN RS15955
gene id: 582899:HDEN_RS15955
uniprot id: D8JWR1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

582899:HDEN RS06170
gene id: 582899:HDEN_RS06170
uniprot id: D8JWF1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

582899:HDEN RS13440
gene id: 582899:HDEN_RS13440
uniprot id: D8JTW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS07230
gene id: 582899:HDEN_RS07230
uniprot id: D8JXR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

582899:HDEN RS03000
gene id: 582899:HDEN_RS03000
uniprot id: D8JSV0
names: Similarity
messages: Belongs to the peptidase S11 family.

582899:HDEN RS02300
gene id: 582899:HDEN_RS02300
uniprot id: D8JS30
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS15885
gene id: 582899:HDEN_RS15885
uniprot id: D8JWP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

582899:HDEN RS13275
gene id: 582899:HDEN_RS13275
uniprot id: D8JTT6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

582899:HDEN RS02115
gene id: 582899:HDEN_RS02115
uniprot id: D8JRM4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

582899:HDEN RS03885
gene id: 582899:HDEN_RS03885
uniprot id: D8JTQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

582899:HDEN RS16185
gene id: 582899:HDEN_RS16185
uniprot id: D8JWV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

582899:HDEN RS01435
gene id: 582899:HDEN_RS01435
uniprot id: D8JQX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS02355
gene id: 582899:HDEN_RS02355
uniprot id: D8JS42
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

582899:HDEN RS01380
gene id: 582899:HDEN_RS01380
uniprot id: D8JQV9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

582899:HDEN RS04115
gene id: 582899:HDEN_RS04115
uniprot id: D8JU66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

582899:HDEN RS03055
gene id: 582899:HDEN_RS03055
uniprot id: D8JSW2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS16920
gene id: 582899:HDEN_RS16920
uniprot id: D8JXN2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

582899:HDEN RS17345
gene id: 582899:HDEN_RS17345
uniprot id: D8JY88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

582899:HDEN RS00165
gene id: 582899:HDEN_RS00165
uniprot id: D8JPG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

582899:HDEN RS17460
gene id: 582899:HDEN_RS17460
uniprot id: D8JYB0
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS09455
gene id: 582899:HDEN_RS09455
uniprot id: D8JZC1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS17090
gene id: 582899:HDEN_RS17090
uniprot id: D8JY38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

582899:HDEN RS14485
gene id: 582899:HDEN_RS14485
uniprot id: D8JUU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

582899:HDEN RS11585
gene id: 582899:HDEN_RS11585
uniprot id: D8JRS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

582899:HDEN RS08110
gene id: 582899:HDEN_RS08110
uniprot id: D8JYK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecG subfamily.
messages: Cell inner membrane

582899:HDEN RS09745
gene id: 582899:HDEN_RS09745
uniprot id: D8JPP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

582899:HDEN RS04190
gene id: 582899:HDEN_RS04190
uniprot id: D8JU81
names: Similarity
messages: Belongs to the YkuD family.

582899:HDEN RS17500
gene id: 582899:HDEN_RS17500
uniprot id: D8JYB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

582899:HDEN RS13210
gene id: 582899:HDEN_RS13210
uniprot id: D8JTF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

582899:HDEN RS08820
gene id: 582899:HDEN_RS08820
uniprot id: D8JYZ7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

582899:HDEN RS09040
gene id: 582899:HDEN_RS09040
uniprot id: D8JZ41
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS09980
gene id: 582899:HDEN_RS09980
uniprot id: D8JPU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

582899:HDEN RS05360
gene id: 582899:HDEN_RS05360
uniprot id: D8JVK7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

582899:HDEN RS14595
gene id: 582899:HDEN_RS14595
uniprot id: D8JV94
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

582899:HDEN RS04325
gene id: 582899:HDEN_RS04325
uniprot id: D8JUA6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS13915
gene id: 582899:HDEN_RS13915
uniprot id: D8JUI1
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS03110
gene id: 582899:HDEN_RS03110
uniprot id: D8JSX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

582899:HDEN RS14230
gene id: 582899:HDEN_RS14230
uniprot id: D8JUP4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

582899:HDEN RS05870
gene id: 582899:HDEN_RS05870
uniprot id: D8JVW3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

582899:HDEN RS11700
gene id: 582899:HDEN_RS11700
uniprot id: D8JRU9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

582899:HDEN RS06405
gene id: 582899:HDEN_RS06405
uniprot id: D8JWJ8
names: Similarity
messages: Belongs to the GcvH family.

582899:HDEN RS09730
gene id: 582899:HDEN_RS09730
uniprot id: D8JPP1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

582899:HDEN RS16175
gene id: 582899:HDEN_RS16175
uniprot id: D8JWV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

582899:HDEN RS15790
gene id: 582899:HDEN_RS15790
uniprot id: D8JWN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

582899:HDEN RS16740
gene id: 582899:HDEN_RS16740
uniprot id: D8JXJ6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

582899:HDEN RS10330
gene id: 582899:HDEN_RS10330
uniprot id: D8JQE0
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS00485
gene id: 582899:HDEN_RS00485
uniprot id: D8JQ02
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

582899:HDEN RS02295
gene id: 582899:HDEN_RS02295
uniprot id: D8JS29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS11100
gene id: 582899:HDEN_RS11100
uniprot id: D8JR64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

582899:HDEN RS10735
gene id: 582899:HDEN_RS10735
uniprot id: D8JQM0
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS15710
gene id: 582899:HDEN_RS15710
uniprot id: D8JW93
names: Similarity
messages: Belongs to the YkuD family.

582899:HDEN RS09710
gene id: 582899:HDEN_RS09710
uniprot id: D8JPN6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS05285
gene id: 582899:HDEN_RS05285
uniprot id: D8JV66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

582899:HDEN RS00915
gene id: 582899:HDEN_RS00915
uniprot id: D8JQ98
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

582899:HDEN RS10860
gene id: 582899:HDEN_RS10860
uniprot id: D8JR16
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS08930
gene id: 582899:HDEN_RS08930
uniprot id: D8JZ20
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

582899:HDEN RS10145
gene id: 582899:HDEN_RS10145
uniprot id: D8JPX3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

582899:HDEN RS10385
gene id: 582899:HDEN_RS10385
uniprot id: D8JQF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

582899:HDEN RS14310
gene id: 582899:HDEN_RS14310
uniprot id: D8JUQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

582899:HDEN RS12165
gene id: 582899:HDEN_RS12165
uniprot id: D8JSG9
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

582899:HDEN RS09180
gene id: 582899:HDEN_RS09180
uniprot id: D8JZ70
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

582899:HDEN RS02285
gene id: 582899:HDEN_RS02285
uniprot id: D8JS27
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS14345
gene id: 582899:HDEN_RS14345
uniprot id: D8JUR6
names: Similarity
messages: Belongs to the threonine synthase family.

582899:HDEN RS10325
gene id: 582899:HDEN_RS10325
uniprot id: D8JQD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

582899:HDEN RS10025
gene id: 582899:HDEN_RS10025
uniprot id: D8JPU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS08460
gene id: 582899:HDEN_RS08460
uniprot id: D8JYS6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

582899:HDEN RS09575
gene id: 582899:HDEN_RS09575
uniprot id: D8JZE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

582899:HDEN RS12915
gene id: 582899:HDEN_RS12915
uniprot id: D8JT96
names: Similarity
messages: Belongs to the AHA1 family.

582899:HDEN RS05605
gene id: 582899:HDEN_RS05605
uniprot id: D8JVQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

582899:HDEN RS11620
gene id: 582899:HDEN_RS11620
uniprot id: D8JRT3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

582899:HDEN RS06185
gene id: 582899:HDEN_RS06185
uniprot id: D8JWF4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

582899:HDEN RS11480
gene id: 582899:HDEN_RS11480
uniprot id: D8JRQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

582899:HDEN RS06230
gene id: 582899:HDEN_RS06230
uniprot id: D8JWG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

582899:HDEN RS08520
gene id: 582899:HDEN_RS08520
uniprot id: D8JYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

582899:HDEN RS11325
gene id: 582899:HDEN_RS11325
uniprot id: D8JRB0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS15295
gene id: 582899:HDEN_RS15295
uniprot id: D8JW11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

582899:HDEN RS07320
gene id: 582899:HDEN_RS07320
uniprot id: D8JXT5
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

582899:HDEN RS08145
gene id: 582899:HDEN_RS08145
uniprot id: D8JYL4
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

582899:HDEN RS03790
gene id: 582899:HDEN_RS03790
uniprot id: D8JTN1
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

582899:HDEN RS08080
gene id: 582899:HDEN_RS08080
uniprot id: D8JYK1
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS08475
gene id: 582899:HDEN_RS08475
uniprot id: D8JYS9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS02975
gene id: 582899:HDEN_RS02975
uniprot id: D8JSU4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

582899:HDEN RS03555
gene id: 582899:HDEN_RS03555
uniprot id: D8JTI7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

582899:HDEN RS11450
gene id: 582899:HDEN_RS11450
uniprot id: D8JRQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

582899:HDEN RS05150
gene id: 582899:HDEN_RS05150
uniprot id: D8JV41
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

582899:HDEN RS04980
gene id: 582899:HDEN_RS04980
uniprot id: D8JV07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

582899:HDEN RS04370
gene id: 582899:HDEN_RS04370
uniprot id: D8JUB5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

582899:HDEN RS03080
gene id: 582899:HDEN_RS03080
uniprot id: D8JSW7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

582899:HDEN RS11065
gene id: 582899:HDEN_RS11065
uniprot id: D8JR57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

582899:HDEN RS13700
gene id: 582899:HDEN_RS13700
uniprot id: D8JU19
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

582899:HDEN RS07965
gene id: 582899:HDEN_RS07965
uniprot id: D8JYH8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

582899:HDEN RS07000
gene id: 582899:HDEN_RS07000
uniprot id: D8JX95
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

582899:HDEN RS07145
gene id: 582899:HDEN_RS07145
uniprot id: D8JXC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

582899:HDEN RS15755
gene id: 582899:HDEN_RS15755
uniprot id: D8JWM3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

582899:HDEN RS15805
gene id: 582899:HDEN_RS15805
uniprot id: D8JWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

582899:HDEN RS03165
gene id: 582899:HDEN_RS03165
uniprot id: D8JSY6
names: Similarity
messages: Belongs to the GST superfamily.

582899:HDEN RS08360
gene id: 582899:HDEN_RS08360
uniprot id: D8JYQ6
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS00355
gene id: 582899:HDEN_RS00355
uniprot id: D8JPK6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS14060
gene id: 582899:HDEN_RS14060
uniprot id: D8JUL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

582899:HDEN RS12555
gene id: 582899:HDEN_RS12555
uniprot id: D8JSP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

582899:HDEN RS15375
gene id: 582899:HDEN_RS15375
uniprot id: D8JW27
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

582899:HDEN RS11080
gene id: 582899:HDEN_RS11080
uniprot id: D8JR60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

582899:HDEN RS17305
gene id: 582899:HDEN_RS17305
uniprot id: D8JY80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

582899:HDEN RS08425
gene id: 582899:HDEN_RS08425
uniprot id: D8JYR9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

582899:HDEN RS17380
gene id: 582899:HDEN_RS17380
uniprot id: D8JY95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

582899:HDEN RS14080
gene id: 582899:HDEN_RS14080
uniprot id: D8JUL4
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

582899:HDEN RS14300
gene id: 582899:HDEN_RS14300
uniprot id: D8JUQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

582899:HDEN RS08790
gene id: 582899:HDEN_RS08790
uniprot id: D8JYZ1
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS05235
gene id: 582899:HDEN_RS05235
uniprot id: D8JV56
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS12720
gene id: 582899:HDEN_RS12720
uniprot id: D8JT57
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

582899:HDEN RS12515
gene id: 582899:HDEN_RS12515
uniprot id: D8JSP0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

582899:HDEN RS09420
gene id: 582899:HDEN_RS09420
uniprot id: D8JZB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

582899:HDEN RS02595
gene id: 582899:HDEN_RS02595
uniprot id: D8JS91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

582899:HDEN RS04655
gene id: 582899:HDEN_RS04655
uniprot id: D8JUG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

582899:HDEN RS05040
gene id: 582899:HDEN_RS05040
uniprot id: D8JV19
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

582899:HDEN RS16685
gene id: 582899:HDEN_RS16685
uniprot id: D8JXI5
names: Similarity
messages: Belongs to the UPF0758 family.

582899:HDEN RS03505
gene id: 582899:HDEN_RS03505
uniprot id: D8JTH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

582899:HDEN RS13720
gene id: 582899:HDEN_RS13720
uniprot id: D8JU23
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

582899:HDEN RS14490
gene id: 582899:HDEN_RS14490
uniprot id: D8JUU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

582899:HDEN RS09050
gene id: 582899:HDEN_RS09050
uniprot id: D8JZ44
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

582899:HDEN RS02005
gene id: 582899:HDEN_RS02005
uniprot id: D8JRK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

582899:HDEN RS17440
gene id: 582899:HDEN_RS17440
uniprot id: D8JYA7
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS05015
gene id: 582899:HDEN_RS05015
uniprot id: D8JV14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

582899:HDEN RS11045
gene id: 582899:HDEN_RS11045
uniprot id: D8JR53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

582899:HDEN RS15365
gene id: 582899:HDEN_RS15365
uniprot id: D8JW25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

582899:HDEN RS00225
gene id: 582899:HDEN_RS00225
uniprot id: D8JPI0
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

582899:HDEN RS17485
gene id: 582899:HDEN_RS17485
uniprot id: D8JYB5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

582899:HDEN RS15230
gene id: 582899:HDEN_RS15230
uniprot id: D8JVZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

582899:HDEN RS02560
gene id: 582899:HDEN_RS02560
uniprot id: D8JS83
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS00020
gene id: 582899:HDEN_RS00020
uniprot id: D8JPE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

582899:HDEN RS16095
gene id: 582899:HDEN_RS16095
uniprot id: D8JWU0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

582899:HDEN RS14095
gene id: 582899:HDEN_RS14095
uniprot id: D8JUL7
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS11785
gene id: 582899:HDEN_RS11785
uniprot id: D8JRW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

582899:HDEN RS05435
gene id: 582899:HDEN_RS05435
uniprot id: D8JVM1
names: Similarity
messages: Belongs to the SufE family.

582899:HDEN RS02665
gene id: 582899:HDEN_RS02665
uniprot id: D8JSA6
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS09370
gene id: 582899:HDEN_RS09370
uniprot id: D8JZA4
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

582899:HDEN RS10100
gene id: 582899:HDEN_RS10100
uniprot id: D8JPW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

582899:HDEN RS16825
gene id: 582899:HDEN_RS16825
uniprot id: D8JXL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

582899:HDEN RS12630
gene id: 582899:HDEN_RS12630
uniprot id: D8JSR3
names: Similarity
messages: Belongs to the DEAD box helicase family.

582899:HDEN RS15550
gene id: 582899:HDEN_RS15550
uniprot id: D8JW61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

582899:HDEN RS10960
gene id: 582899:HDEN_RS10960
uniprot id: D8JR37
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

582899:HDEN RS00305
gene id: 582899:HDEN_RS00305
uniprot id: D8JPJ6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

582899:HDEN RS02700
gene id: 582899:HDEN_RS02700
uniprot id: D8JSB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

582899:HDEN RS14430
gene id: 582899:HDEN_RS14430
uniprot id: D8JUT3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

582899:HDEN RS03090
gene id: 582899:HDEN_RS03090
uniprot id: D8JSW9
names: Similarity
messages: Belongs to the DprA/Smf family.

582899:HDEN RS07155
gene id: 582899:HDEN_RS07155
uniprot id: D8JXQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

582899:HDEN RS04745
gene id: 582899:HDEN_RS04745
uniprot id: D8JUW2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

582899:HDEN RS14580
gene id: 582899:HDEN_RS14580
uniprot id: D8JV90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

582899:HDEN RS04140
gene id: 582899:HDEN_RS04140
uniprot id: D8JU71
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

582899:HDEN RS09990
gene id: 582899:HDEN_RS09990
uniprot id: D8JPU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

582899:HDEN RS16070
gene id: 582899:HDEN_RS16070
uniprot id: D8JWT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

582899:HDEN RS15340
gene id: 582899:HDEN_RS15340
uniprot id: D8JW20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

582899:HDEN RS01930
gene id: 582899:HDEN_RS01930
uniprot id: D8JRI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

582899:HDEN RS06835
gene id: 582899:HDEN_RS06835
uniprot id: D8JX62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

582899:HDEN RS16055
gene id: 582899:HDEN_RS16055
uniprot id: D8JWT1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

582899:HDEN RS02525
gene id: 582899:HDEN_RS02525
uniprot id: D8JS76
names: Similarity
messages: Belongs to the glutamate synthase family.

582899:HDEN RS06510
gene id: 582899:HDEN_RS06510
uniprot id: D8JWL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methanol dehydrogenase subunit 2 family.
messages: Catalyzes the oxidation of primary alcohols including methanol.
messages: Heterotetramer composed of 2 alpha and 2 beta subunits.

582899:HDEN RS17490
gene id: 582899:HDEN_RS17490
uniprot id: D8JYB6
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

582899:HDEN RS02505
gene id: 582899:HDEN_RS02505
uniprot id: D8JS72
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

582899:HDEN RS13920
gene id: 582899:HDEN_RS13920
uniprot id: D8JUI2
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS04110
gene id: 582899:HDEN_RS04110
uniprot id: D8JU65
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

582899:HDEN RS01195
gene id: 582899:HDEN_RS01195
uniprot id: D8JQS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

582899:HDEN RS12995
gene id: 582899:HDEN_RS12995
uniprot id: D8JTB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

582899:HDEN RS09405
gene id: 582899:HDEN_RS09405
uniprot id: D8JZB1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS01965
gene id: 582899:HDEN_RS01965
uniprot id: D8JRJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

582899:HDEN RS13640
gene id: 582899:HDEN_RS13640
uniprot id: D8JU07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

582899:HDEN RS17660
gene id: 582899:HDEN_RS17660
uniprot id: D8JS21
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

582899:HDEN RS03105
gene id: 582899:HDEN_RS03105
uniprot id: D8JSX2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

582899:HDEN RS11930
gene id: 582899:HDEN_RS11930
uniprot id: D8JRZ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS10730
gene id: 582899:HDEN_RS10730
uniprot id: D8JQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

582899:HDEN RS16690
gene id: 582899:HDEN_RS16690
uniprot id: D8JXI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

582899:HDEN RS09495
gene id: 582899:HDEN_RS09495
uniprot id: D8JZC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

582899:HDEN RS06915
gene id: 582899:HDEN_RS06915
uniprot id: D8JX78
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

582899:HDEN RS09255
gene id: 582899:HDEN_RS09255
uniprot id: D8JZ83
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Binds 2 calcium ions per subunit.
messages: Binds 6 Cu cations per subunit. Each subunit contains 2 copper centers; Cu(A) (binuclear) and Cu(Z) (tetranuclear). Cu(Z) is thought to be the site of nitrous oxide reduction.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

582899:HDEN RS01245
gene id: 582899:HDEN_RS01245
uniprot id: D8JQT1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

582899:HDEN RS14325
gene id: 582899:HDEN_RS14325
uniprot id: D8JUR2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

582899:HDEN RS09645
gene id: 582899:HDEN_RS09645
uniprot id: D8JPM4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

582899:HDEN RS01485
gene id: 582899:HDEN_RS01485
uniprot id: D8JQY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

582899:HDEN RS14050
gene id: 582899:HDEN_RS14050
uniprot id: D8JUK8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

582899:HDEN RS12045
gene id: 582899:HDEN_RS12045
uniprot id: D8JSE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

582899:HDEN RS03010
gene id: 582899:HDEN_RS03010
uniprot id: D8JSV3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

582899:HDEN RS16520
gene id: 582899:HDEN_RS16520
uniprot id: D8JXF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

582899:HDEN RS07040
gene id: 582899:HDEN_RS07040
uniprot id: D8JXA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

582899:HDEN RS09165
gene id: 582899:HDEN_RS09165
uniprot id: D8JZ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

582899:HDEN RS09025
gene id: 582899:HDEN_RS09025
uniprot id: D8JZ38
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

582899:HDEN RS06190
gene id: 582899:HDEN_RS06190
uniprot id: D8JWF5
names: Similarity
messages: Belongs to the HesB/IscA family.

582899:HDEN RS06930
gene id: 582899:HDEN_RS06930
uniprot id: D8JX81
names: Similarity
messages: Belongs to the CFA/CMAS family.

582899:HDEN RS04800
gene id: 582899:HDEN_RS04800
uniprot id: D8JUX3
names: Similarity
messages: Belongs to the glutamine synthetase family.

582899:HDEN RS15335
gene id: 582899:HDEN_RS15335
uniprot id: D8JW19
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

582899:HDEN RS10710
gene id: 582899:HDEN_RS10710
uniprot id: D8JQL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

582899:HDEN RS11055
gene id: 582899:HDEN_RS11055
uniprot id: D8JR55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

582899:HDEN RS11090
gene id: 582899:HDEN_RS11090
uniprot id: D8JR62
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

582899:HDEN RS15580
gene id: 582899:HDEN_RS15580
uniprot id: D8JW67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

582899:HDEN RS15285
gene id: 582899:HDEN_RS15285
uniprot id: D8JW09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

582899:HDEN RS15415
gene id: 582899:HDEN_RS15415
uniprot id: D8JW34
names: Similarity
messages: Belongs to the GcvT family.

582899:HDEN RS07870
gene id: 582899:HDEN_RS07870
uniprot id: D8JYF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

582899:HDEN RS08375
gene id: 582899:HDEN_RS08375
uniprot id: D8JYQ9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

582899:HDEN RS02435
gene id: 582899:HDEN_RS02435
uniprot id: D8JS58
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS04755
gene id: 582899:HDEN_RS04755
uniprot id: D8JUW4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

582899:HDEN RS04780
gene id: 582899:HDEN_RS04780
uniprot id: D8JUW9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

582899:HDEN RS15875
gene id: 582899:HDEN_RS15875
uniprot id: D8JWP6
names: Similarity
messages: Belongs to the YggT family.

582899:HDEN RS06690
gene id: 582899:HDEN_RS06690
uniprot id: D8JX33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

582899:HDEN RS08920
gene id: 582899:HDEN_RS08920
uniprot id: D8JZ18
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

582899:HDEN RS04760
gene id: 582899:HDEN_RS04760
uniprot id: D8JUW5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

582899:HDEN RS00465
gene id: 582899:HDEN_RS00465
uniprot id: D8JPZ8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

582899:HDEN RS08725
gene id: 582899:HDEN_RS08725
uniprot id: D8JYX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

582899:HDEN RS13025
gene id: 582899:HDEN_RS13025
uniprot id: D8JTB8
names: Similarity
messages: Belongs to the UPF0335 family.

582899:HDEN RS08465
gene id: 582899:HDEN_RS08465
uniprot id: D8JYS7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

582899:HDEN RS00905
gene id: 582899:HDEN_RS00905
uniprot id: D8JQ96
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

582899:HDEN RS08600
gene id: 582899:HDEN_RS08600
uniprot id: D8JYV1
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS12715
gene id: 582899:HDEN_RS12715
uniprot id: D8JT56
names: Similarity
messages: Belongs to the CobT family.

582899:HDEN RS16085
gene id: 582899:HDEN_RS16085
uniprot id: D8JWT8
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

582899:HDEN RS08390
gene id: 582899:HDEN_RS08390
uniprot id: D8JYR2
names: Similarity
messages: Belongs to the YicC/YloC family.

582899:HDEN RS16385
gene id: 582899:HDEN_RS16385
uniprot id: D8JWZ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

582899:HDEN RS03440
gene id: 582899:HDEN_RS03440
uniprot id: D8JRM4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

582899:HDEN RS05095
gene id: 582899:HDEN_RS05095
uniprot id: D8JV30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

582899:HDEN RS15275
gene id: 582899:HDEN_RS15275
uniprot id: D8JW07
names: Similarity
messages: Belongs to the MotB family.

582899:HDEN RS08770
gene id: 582899:HDEN_RS08770
uniprot id: D8JYY7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

582899:HDEN RS10955
gene id: 582899:HDEN_RS10955
uniprot id: D8JR36
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS16770
gene id: 582899:HDEN_RS16770
uniprot id: D8JXK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

582899:HDEN RS07895
gene id: 582899:HDEN_RS07895
uniprot id: D8JYG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
messages: Cytoplasm
messages: Homotetramer.

582899:HDEN RS13445
gene id: 582899:HDEN_RS13445
uniprot id: D8JTW8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

582899:HDEN RS12600
gene id: 582899:HDEN_RS12600
uniprot id: D8JSQ7
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS12700
gene id: 582899:HDEN_RS12700
uniprot id: D8JT53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

582899:HDEN RS11990
gene id: 582899:HDEN_RS11990
uniprot id: D8JS09
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS15750
gene id: 582899:HDEN_RS15750
uniprot id: D8JWM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

582899:HDEN RS04420
gene id: 582899:HDEN_RS04420
uniprot id: D8JUC6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS03095
gene id: 582899:HDEN_RS03095
uniprot id: D8JSX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

582899:HDEN RS09655
gene id: 582899:HDEN_RS09655
uniprot id: D8JPM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

582899:HDEN RS08450
gene id: 582899:HDEN_RS08450
uniprot id: D8JYS4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

582899:HDEN RS10365
gene id: 582899:HDEN_RS10365
uniprot id: D8JQE7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

582899:HDEN RS06770
gene id: 582899:HDEN_RS06770
uniprot id: D8JX49
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

582899:HDEN RS08410
gene id: 582899:HDEN_RS08410
uniprot id: D8JYR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

582899:HDEN RS16080
gene id: 582899:HDEN_RS16080
uniprot id: D8JWT7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS01855
gene id: 582899:HDEN_RS01855
uniprot id: D8JRH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

582899:HDEN RS17115
gene id: 582899:HDEN_RS17115
uniprot id: D8JY43
names: Similarity
messages: Belongs to the SDHAF4 family.

582899:HDEN RS08130
gene id: 582899:HDEN_RS08130
uniprot id: D8JYL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

582899:HDEN RS16905
gene id: 582899:HDEN_RS16905
uniprot id: D8JXM9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

582899:HDEN RS16665
gene id: 582899:HDEN_RS16665
uniprot id: D8JXI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

582899:HDEN RS01765
gene id: 582899:HDEN_RS01765
uniprot id: D8JRF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

582899:HDEN RS12910
gene id: 582899:HDEN_RS12910
uniprot id: D8JT95
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

582899:HDEN RS06225
gene id: 582899:HDEN_RS06225
uniprot id: D8JWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

582899:HDEN RS05100
gene id: 582899:HDEN_RS05100
uniprot id: D8JV31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

582899:HDEN RS11950
gene id: 582899:HDEN_RS11950
uniprot id: D8JRZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

582899:HDEN RS01540
gene id: 582899:HDEN_RS01540
uniprot id: D8JQZ2
names: Similarity
messages: Belongs to the bacterial secretin family.

582899:HDEN RS12970
gene id: 582899:HDEN_RS12970
uniprot id: D8JTA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

582899:HDEN RS10765
gene id: 582899:HDEN_RS10765
uniprot id: D8JQM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

582899:HDEN RS15715
gene id: 582899:HDEN_RS15715
uniprot id: D8JW94
names: Similarity
messages: Belongs to the YkuD family.

582899:HDEN RS05120
gene id: 582899:HDEN_RS05120
uniprot id: D8JV35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

582899:HDEN RS04035
gene id: 582899:HDEN_RS04035
uniprot id: D8JTS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

582899:HDEN RS15585
gene id: 582899:HDEN_RS15585
uniprot id: D8JW68
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

582899:HDEN RS06865
gene id: 582899:HDEN_RS06865
uniprot id: D8JX68
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

582899:HDEN RS10420
gene id: 582899:HDEN_RS10420
uniprot id: D8JQF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS02635
gene id: 582899:HDEN_RS02635
uniprot id: D8JQA1
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

582899:HDEN RS14935
gene id: 582899:HDEN_RS14935
uniprot id: D8JVG4
names: Function
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

582899:HDEN RS09075
gene id: 582899:HDEN_RS09075
uniprot id: D8JZ49
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

582899:HDEN RS00150
gene id: 582899:HDEN_RS00150
uniprot id: D8JPG5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

582899:HDEN RS09305
gene id: 582899:HDEN_RS09305
uniprot id: D8JZ93
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS09410
gene id: 582899:HDEN_RS09410
uniprot id: D8JZB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

582899:HDEN RS05010
gene id: 582899:HDEN_RS05010
uniprot id: D8JV13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

582899:HDEN RS12845
gene id: 582899:HDEN_RS12845
uniprot id: D8JT81
names: Similarity
messages: Belongs to the peptidase M16 family.

582899:HDEN RS07955
gene id: 582899:HDEN_RS07955
uniprot id: D8JYH6
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

582899:HDEN RS14365
gene id: 582899:HDEN_RS14365
uniprot id: D8JUS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

582899:HDEN RS03060
gene id: 582899:HDEN_RS03060
uniprot id: D8JSW3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

582899:HDEN RS14245
gene id: 582899:HDEN_RS14245
uniprot id: D8JUP7
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

582899:HDEN RS10770
gene id: 582899:HDEN_RS10770
uniprot id: D8JQM6
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

582899:HDEN RS01220
gene id: 582899:HDEN_RS01220
uniprot id: D8JQS6
names: Similarity
messages: Belongs to the peptidase M24B family.

582899:HDEN RS15670
gene id: 582899:HDEN_RS15670
uniprot id: D8JW84
names: Similarity
messages: Belongs to the BolA/IbaG family.

582899:HDEN RS08830
gene id: 582899:HDEN_RS08830
uniprot id: D8JYZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

582899:HDEN RS09435
gene id: 582899:HDEN_RS09435
uniprot id: D8JZB7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

582899:HDEN RS08400
gene id: 582899:HDEN_RS08400
uniprot id: D8JYR4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

582899:HDEN RS03660
gene id: 582899:HDEN_RS03660
uniprot id: D8JTK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

582899:HDEN RS06265
gene id: 582899:HDEN_RS06265
uniprot id: D8JWH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

582899:HDEN RS09880
gene id: 582899:HDEN_RS09880
uniprot id: D8JPS1
names: Similarity
messages: Belongs to the RNase T2 family.

582899:HDEN RS09850
gene id: 582899:HDEN_RS09850
uniprot id: D8JPR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

582899:HDEN RS02070
gene id: 582899:HDEN_RS02070
uniprot id: D8JRL6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

582899:HDEN RS17365
gene id: 582899:HDEN_RS17365
uniprot id: D8JY92
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

582899:HDEN RS07455
gene id: 582899:HDEN_RS07455
uniprot id: D8JXW3
names: Similarity
messages: Belongs to the YkuD family.

582899:HDEN RS11970
gene id: 582899:HDEN_RS11970
uniprot id: D8JS05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

582899:HDEN RS01265
gene id: 582899:HDEN_RS01265
uniprot id: D8JQT5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

582899:HDEN RS07200
gene id: 582899:HDEN_RS07200
uniprot id: D8JXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS04700
gene id: 582899:HDEN_RS04700
uniprot id: D8JUV2
names: Similarity
messages: Belongs to the YkuD family.

582899:HDEN RS17215
gene id: 582899:HDEN_RS17215
uniprot id: D8JY62
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

582899:HDEN RS00120
gene id: 582899:HDEN_RS00120
uniprot id: D8JPG0
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

582899:HDEN RS10015
gene id: 582899:HDEN_RS10015
uniprot id: D8JPU7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

582899:HDEN RS04200
gene id: 582899:HDEN_RS04200
uniprot id: D8JU82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

582899:HDEN RS13285
gene id: 582899:HDEN_RS13285
uniprot id: D8JTT8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

582899:HDEN RS04105
gene id: 582899:HDEN_RS04105
uniprot id: D8JU64
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

582899:HDEN RS12740
gene id: 582899:HDEN_RS12740
uniprot id: D8JT60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

582899:HDEN RS08730
gene id: 582899:HDEN_RS08730
uniprot id: D8JYX9
names: Similarity
messages: Belongs to the pirin family.

582899:HDEN RS00925
gene id: 582899:HDEN_RS00925
uniprot id: D8JQA0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

582899:HDEN RS16015
gene id: 582899:HDEN_RS16015
uniprot id: D8JWS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS08895
gene id: 582899:HDEN_RS08895
uniprot id: D8JZ13
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

582899:HDEN RS04435
gene id: 582899:HDEN_RS04435
uniprot id: D8JUC9
names: Similarity
messages: Belongs to the AHA1 family.

582899:HDEN RS13825
gene id: 582899:HDEN_RS13825
uniprot id: D8JU45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

582899:HDEN RS09725
gene id: 582899:HDEN_RS09725
uniprot id: D8JPN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

582899:HDEN RS14515
gene id: 582899:HDEN_RS14515
uniprot id: D8JV77
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

582899:HDEN RS11510
gene id: 582899:HDEN_RS11510
uniprot id: D8JRR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

582899:HDEN RS16785
gene id: 582899:HDEN_RS16785
uniprot id: D8JXK5
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS17570
gene id: 582899:HDEN_RS17570
uniprot id: D8JYC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

582899:HDEN RS13405
gene id: 582899:HDEN_RS13405
uniprot id: D8JTW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

582899:HDEN RS15735
gene id: 582899:HDEN_RS15735
uniprot id: D8JW98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

582899:HDEN RS13055
gene id: 582899:HDEN_RS13055
uniprot id: D8JTC4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

582899:HDEN RS07505
gene id: 582899:HDEN_RS07505
uniprot id: D8JXX4
names: Subcellular Location Annotation
messages: Cytoplasm

582899:HDEN RS01125
gene id: 582899:HDEN_RS01125
uniprot id: D8JQQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

582899:HDEN RS02575
gene id: 582899:HDEN_RS02575
uniprot id: D8JS86
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

582899:HDEN RS05070
gene id: 582899:HDEN_RS05070
uniprot id: D8JV25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

582899:HDEN RS16325
gene id: 582899:HDEN_RS16325
uniprot id: D8JWY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

582899:HDEN RS16410
gene id: 582899:HDEN_RS16410
uniprot id: D8JXD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

582899:HDEN RS13415
gene id: 582899:HDEN_RS13415
uniprot id: D8JTW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

582899:HDEN RS12430
gene id: 582899:HDEN_RS12430
uniprot id: D8JSM2
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

582899:HDEN RS10915
gene id: 582899:HDEN_RS10915
uniprot id: D8JR28
names: Similarity
messages: Belongs to the YkuD family.

582899:HDEN RS16170
gene id: 582899:HDEN_RS16170
uniprot id: D8JWV5
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

582899:HDEN RS11900
gene id: 582899:HDEN_RS11900
uniprot id: D8JRY9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

582899:HDEN RS11830
gene id: 582899:HDEN_RS11830
uniprot id: D8JRX5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS09185
gene id: 582899:HDEN_RS09185
uniprot id: D8JZ71
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

582899:HDEN RS15975
gene id: 582899:HDEN_RS15975
uniprot id: D8JWR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

582899:HDEN RS16350
gene id: 582899:HDEN_RS16350
uniprot id: D8JWZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

582899:HDEN RS05060
gene id: 582899:HDEN_RS05060
uniprot id: D8JV23
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

582899:HDEN RS04815
gene id: 582899:HDEN_RS04815
uniprot id: D8JUX6
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

582899:HDEN RS01300
gene id: 582899:HDEN_RS01300
uniprot id: D8JQU3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

582899:HDEN RS06290
gene id: 582899:HDEN_RS06290
uniprot id: D8JWH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

582899:HDEN RS12080
gene id: 582899:HDEN_RS12080
uniprot id: D8JSF1
names: Similarity
messages: Belongs to the YkuD family.

582899:HDEN RS17125
gene id: 582899:HDEN_RS17125
uniprot id: D8JY45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

582899:HDEN RS01605
gene id: 582899:HDEN_RS01605
uniprot id: D8JR05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS00260
gene id: 582899:HDEN_RS00260
uniprot id: D8JPI7
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS06535
gene id: 582899:HDEN_RS06535
uniprot id: D8JX01
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

582899:HDEN RS00985
gene id: 582899:HDEN_RS00985
uniprot id: D8JQB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

582899:HDEN RS10300
gene id: 582899:HDEN_RS10300
uniprot id: D8JQD4
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS05125
gene id: 582899:HDEN_RS05125
uniprot id: D8JV36
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

582899:HDEN RS10475
gene id: 582899:HDEN_RS10475
uniprot id: D8JQG9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

582899:HDEN RS16165
gene id: 582899:HDEN_RS16165
uniprot id: D8JWV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

582899:HDEN RS00275
gene id: 582899:HDEN_RS00275
uniprot id: D8JPJ0
names: Similarity
messages: Belongs to the peptidase S11 family.

582899:HDEN RS09240
gene id: 582899:HDEN_RS09240
uniprot id: D8JZ80
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS13475
gene id: 582899:HDEN_RS13475
uniprot id: D8JTX4
names: Function
messages: Multidrug efflux pump.

582899:HDEN RS06830
gene id: 582899:HDEN_RS06830
uniprot id: D8JX61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

582899:HDEN RS03490
gene id: 582899:HDEN_RS03490
uniprot id: D8JTH5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

582899:HDEN RS16760
gene id: 582899:HDEN_RS16760
uniprot id: D8JXK0
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS13335
gene id: 582899:HDEN_RS13335
uniprot id: D8JTU8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

582899:HDEN RS05005
gene id: 582899:HDEN_RS05005
uniprot id: D8JV12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

582899:HDEN RS14900
gene id: 582899:HDEN_RS14900
uniprot id: D8JVF6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

582899:HDEN RS13875
gene id: 582899:HDEN_RS13875
uniprot id: D8JUH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

582899:HDEN RS12840
gene id: 582899:HDEN_RS12840
uniprot id: D8JT80
names: Similarity
messages: Belongs to the GPI family.

582899:HDEN RS10980
gene id: 582899:HDEN_RS10980
uniprot id: D8JR41
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS07510
gene id: 582899:HDEN_RS07510
uniprot id: D8JXX5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

582899:HDEN RS14505
gene id: 582899:HDEN_RS14505
uniprot id: D8JV75
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS02315
gene id: 582899:HDEN_RS02315
uniprot id: D8JS34
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

582899:HDEN RS11040
gene id: 582899:HDEN_RS11040
uniprot id: D8JR52
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

582899:HDEN RS01565
gene id: 582899:HDEN_RS01565
uniprot id: D8JQZ7
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS15925
gene id: 582899:HDEN_RS15925
uniprot id: D8JWQ5
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

582899:HDEN RS08435
gene id: 582899:HDEN_RS08435
uniprot id: D8JYS1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

582899:HDEN RS01710
gene id: 582899:HDEN_RS01710
uniprot id: D8JRE8
names: Similarity
messages: Belongs to the DEAD box helicase family.

582899:HDEN RS06850
gene id: 582899:HDEN_RS06850
uniprot id: D8JX65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

582899:HDEN RS15890
gene id: 582899:HDEN_RS15890
uniprot id: D8JWP9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

582899:HDEN RS17225
gene id: 582899:HDEN_RS17225
uniprot id: D8JY64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

582899:HDEN RS00515
gene id: 582899:HDEN_RS00515
uniprot id: D8JQ09
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS16865
gene id: 582899:HDEN_RS16865
uniprot id: D8JXM1
names: Similarity
messages: Belongs to the peptidase S41A family.

582899:HDEN RS16860
gene id: 582899:HDEN_RS16860
uniprot id: D8JXM0
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

582899:HDEN RS13230
gene id: 582899:HDEN_RS13230
uniprot id: D8JTF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

582899:HDEN RS08120
gene id: 582899:HDEN_RS08120
uniprot id: D8JYK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

582899:HDEN RS00220
gene id: 582899:HDEN_RS00220
uniprot id: D8JPH9
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

582899:HDEN RS13185
gene id: 582899:HDEN_RS13185
uniprot id: D8JTE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

582899:HDEN RS17600
gene id: 582899:HDEN_RS17600
uniprot id: D8JYD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

582899:HDEN RS16540
gene id: 582899:HDEN_RS16540
uniprot id: D8JXF6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

582899:HDEN RS01295
gene id: 582899:HDEN_RS01295
uniprot id: D8JQU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

582899:HDEN RS04785
gene id: 582899:HDEN_RS04785
uniprot id: D8JUX0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

582899:HDEN RS11525
gene id: 582899:HDEN_RS11525
uniprot id: D8JRR5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

582899:HDEN RS11690
gene id: 582899:HDEN_RS11690
uniprot id: D8JRU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS01130
gene id: 582899:HDEN_RS01130
uniprot id: D8JQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

582899:HDEN RS16125
gene id: 582899:HDEN_RS16125
uniprot id: D8JWU6
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

582899:HDEN RS03475
gene id: 582899:HDEN_RS03475
uniprot id: D8JRM4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

582899:HDEN RS17210
gene id: 582899:HDEN_RS17210
uniprot id: D8JY61
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

582899:HDEN RS04560
gene id: 582899:HDEN_RS04560
uniprot id: D8JUF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

582899:HDEN RS15465
gene id: 582899:HDEN_RS15465
uniprot id: D8JW45
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

582899:HDEN RS00155
gene id: 582899:HDEN_RS00155
uniprot id: D8JPG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

582899:HDEN RS08455
gene id: 582899:HDEN_RS08455
uniprot id: D8JYS5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

582899:HDEN RS07475
gene id: 582899:HDEN_RS07475
uniprot id: D8JXW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

582899:HDEN RS08775
gene id: 582899:HDEN_RS08775
uniprot id: D8JYY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

582899:HDEN RS16110
gene id: 582899:HDEN_RS16110
uniprot id: D8JWU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

582899:HDEN RS03255
gene id: 582899:HDEN_RS03255
uniprot id: D8JT04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

582899:HDEN RS16505
gene id: 582899:HDEN_RS16505
uniprot id: D8JXE9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

582899:HDEN RS06335
gene id: 582899:HDEN_RS06335
uniprot id: D8JWI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

582899:HDEN RS17375
gene id: 582899:HDEN_RS17375
uniprot id: D8JY94
names: Similarity
messages: Belongs to the thioester dehydratase family. FabA subfamily.

582899:HDEN RS04320
gene id: 582899:HDEN_RS04320
uniprot id: D8JUA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

582899:HDEN RS05610
gene id: 582899:HDEN_RS05610
uniprot id: D8JVQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS06890
gene id: 582899:HDEN_RS06890
uniprot id: D8JX73
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

582899:HDEN RS04095
gene id: 582899:HDEN_RS04095
uniprot id: D8JU62
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

582899:HDEN RS02830
gene id: 582899:HDEN_RS02830
uniprot id: D8JSR5
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS07110
gene id: 582899:HDEN_RS07110
uniprot id: D8JXB7
names: Similarity
messages: Belongs to the TrpC family.

582899:HDEN RS09855
gene id: 582899:HDEN_RS09855
uniprot id: D8JPR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

582899:HDEN RS13515
gene id: 582899:HDEN_RS13515
uniprot id: D8JTY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

582899:HDEN RS16225
gene id: 582899:HDEN_RS16225
uniprot id: D8JWW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

582899:HDEN RS04430
gene id: 582899:HDEN_RS04430
uniprot id: D8JUC8
names: Similarity
messages: Belongs to the YciI family.

582899:HDEN RS05140
gene id: 582899:HDEN_RS05140
uniprot id: D8JV39
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

582899:HDEN RS15930
gene id: 582899:HDEN_RS15930
uniprot id: D8JWQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

582899:HDEN RS10845
gene id: 582899:HDEN_RS10845
uniprot id: D8JR13
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

582899:HDEN RS15145
gene id: 582899:HDEN_RS15145
uniprot id: D8JVY0
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

582899:HDEN RS12315
gene id: 582899:HDEN_RS12315
uniprot id: D8JSJ8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

582899:HDEN RS00090
gene id: 582899:HDEN_RS00090
uniprot id: D8JPF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

582899:HDEN RS16105
gene id: 582899:HDEN_RS16105
uniprot id: D8JWU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

582899:HDEN RS05410
gene id: 582899:HDEN_RS05410
uniprot id: D8JVL7
names: Similarity
messages: Belongs to the peptidase S9A family.

582899:HDEN RS13170
gene id: 582899:HDEN_RS13170
uniprot id: D8JTE5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

582899:HDEN RS08095
gene id: 582899:HDEN_RS08095
uniprot id: D8JYK4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

582899:HDEN RS09465
gene id: 582899:HDEN_RS09465
uniprot id: D8JZC3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

582899:HDEN RS07030
gene id: 582899:HDEN_RS07030
uniprot id: D8JXA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

582899:HDEN RS16610
gene id: 582899:HDEN_RS16610
uniprot id: D8JXH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

582899:HDEN RS10440
gene id: 582899:HDEN_RS10440
uniprot id: D8JQG2
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS08705
gene id: 582899:HDEN_RS08705
uniprot id: D8JYX3
names: Similarity
messages: Belongs to the thioesterase PaaI family.

582899:HDEN RS11025
gene id: 582899:HDEN_RS11025
uniprot id: D8JR49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

582899:HDEN RS10160
gene id: 582899:HDEN_RS10160
uniprot id: D8JPX6
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

582899:HDEN RS10230
gene id: 582899:HDEN_RS10230
uniprot id: D8JQC1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS14065
gene id: 582899:HDEN_RS14065
uniprot id: D8JUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

582899:HDEN RS16180
gene id: 582899:HDEN_RS16180
uniprot id: D8JWV7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS10140
gene id: 582899:HDEN_RS10140
uniprot id: D8JPX2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS04995
gene id: 582899:HDEN_RS04995
uniprot id: D8JV10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

582899:HDEN RS15355
gene id: 582899:HDEN_RS15355
uniprot id: D8JW23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

582899:HDEN RS12460
gene id: 582899:HDEN_RS12460
uniprot id: D8JSM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

582899:HDEN RS16200
gene id: 582899:HDEN_RS16200
uniprot id: D8JWW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

582899:HDEN RS01645
gene id: 582899:HDEN_RS01645
uniprot id: D8JRD6
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

582899:HDEN RS15740
gene id: 582899:HDEN_RS15740
uniprot id: D8JW99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

582899:HDEN RS08480
gene id: 582899:HDEN_RS08480
uniprot id: D8JYT0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

582899:HDEN RS17425
gene id: 582899:HDEN_RS17425
uniprot id: D8JYA4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

582899:HDEN RS17615
gene id: 582899:HDEN_RS17615
uniprot id: D8JYD6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

582899:HDEN RS01325
gene id: 582899:HDEN_RS01325
uniprot id: D8JQU8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

582899:HDEN RS03680
gene id: 582899:HDEN_RS03680
uniprot id: D8JTL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

582899:HDEN RS01020
gene id: 582899:HDEN_RS01020
uniprot id: D8JQN7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

582899:HDEN RS09635
gene id: 582899:HDEN_RS09635
uniprot id: D8JPM2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

582899:HDEN RS08300
gene id: 582899:HDEN_RS08300
uniprot id: D8JYP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

582899:HDEN RS10315
gene id: 582899:HDEN_RS10315
uniprot id: D8JQD7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

582899:HDEN RS14290
gene id: 582899:HDEN_RS14290
uniprot id: D8JUQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

582899:HDEN RS11015
gene id: 582899:HDEN_RS11015
uniprot id: D8JR47
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

582899:HDEN RS17240
gene id: 582899:HDEN_RS17240
uniprot id: D8JY67
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

582899:HDEN RS04885
gene id: 582899:HDEN_RS04885
uniprot id: D8JUZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

582899:HDEN RS10120
gene id: 582899:HDEN_RS10120
uniprot id: D8JPW8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

582899:HDEN RS12710
gene id: 582899:HDEN_RS12710
uniprot id: D8JT55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

582899:HDEN RS11555
gene id: 582899:HDEN_RS11555
uniprot id: D8JRS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

582899:HDEN RS16890
gene id: 582899:HDEN_RS16890
uniprot id: D8JXM6
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

582899:HDEN RS10240
gene id: 582899:HDEN_RS10240
uniprot id: D8JQC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

582899:HDEN RS01165
gene id: 582899:HDEN_RS01165
uniprot id: D8JQR5
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS05565
gene id: 582899:HDEN_RS05565
uniprot id: D8JVP7
names: Similarity
messages: Belongs to the peptidase C40 family.

582899:HDEN RS11370
gene id: 582899:HDEN_RS11370
uniprot id: D8JRB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

582899:HDEN RS10445
gene id: 582899:HDEN_RS10445
uniprot id: D8JQG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

582899:HDEN RS05080
gene id: 582899:HDEN_RS05080
uniprot id: D8JV27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

582899:HDEN RS05135
gene id: 582899:HDEN_RS05135
uniprot id: D8JV38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

582899:HDEN RS16205
gene id: 582899:HDEN_RS16205
uniprot id: D8JWW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rho family.
messages: Cell inner membrane
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS12980
gene id: 582899:HDEN_RS12980
uniprot id: D8JTA9
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

582899:HDEN RS13605
gene id: 582899:HDEN_RS13605
uniprot id: D8JU00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

582899:HDEN RS08440
gene id: 582899:HDEN_RS08440
uniprot id: D8JYS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

582899:HDEN RS05105
gene id: 582899:HDEN_RS05105
uniprot id: D8JV32
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

582899:HDEN RS08780
gene id: 582899:HDEN_RS08780
uniprot id: D8JYY9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS02750
gene id: 582899:HDEN_RS02750
uniprot id: D8JSC3
names: Subcellular Location Annotation
messages: Peroxisome

582899:HDEN RS08010
gene id: 582899:HDEN_RS08010
uniprot id: D8JYI7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

582899:HDEN RS09560
gene id: 582899:HDEN_RS09560
uniprot id: D8JZE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

582899:HDEN RS16435
gene id: 582899:HDEN_RS16435
uniprot id: D8JXD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

582899:HDEN RS05030
gene id: 582899:HDEN_RS05030
uniprot id: D8JV17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

582899:HDEN RS00035
gene id: 582899:HDEN_RS00035
uniprot id: D8JPE3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

582899:HDEN RS09505
gene id: 582899:HDEN_RS09505
uniprot id: D8JZD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

582899:HDEN RS02130
gene id: 582899:HDEN_RS02130
uniprot id: D8JRM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

582899:HDEN RS08090
gene id: 582899:HDEN_RS08090
uniprot id: D8JYK3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS10275
gene id: 582899:HDEN_RS10275
uniprot id: D8JQC9
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 copper ion per subunit.
messages: Periplasm

582899:HDEN RS06925
gene id: 582899:HDEN_RS06925
uniprot id: D8JX80
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

582899:HDEN RS11420
gene id: 582899:HDEN_RS11420
uniprot id: D8JRP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS13615
gene id: 582899:HDEN_RS13615
uniprot id: D8JU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

582899:HDEN RS10920
gene id: 582899:HDEN_RS10920
uniprot id: D8JR29
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

582899:HDEN RS10290
gene id: 582899:HDEN_RS10290
uniprot id: D8JQD2
names: Similarity
messages: Belongs to the LOG family.

582899:HDEN RS02965
gene id: 582899:HDEN_RS02965
uniprot id: D8JSU2
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

582899:HDEN RS12280
gene id: 582899:HDEN_RS12280
uniprot id: D8JSJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS13955
gene id: 582899:HDEN_RS13955
uniprot id: D8JUI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

582899:HDEN RS02715
gene id: 582899:HDEN_RS02715
uniprot id: D8JSB6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

582899:HDEN RS09490
gene id: 582899:HDEN_RS09490
uniprot id: D8JZC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

582899:HDEN RS01305
gene id: 582899:HDEN_RS01305
uniprot id: D8JQU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

582899:HDEN RS11460
gene id: 582899:HDEN_RS11460
uniprot id: D8JRQ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

582899:HDEN RS16705
gene id: 582899:HDEN_RS16705
uniprot id: D8JXI9
names: Similarity
messages: Belongs to the YkuD family.

582899:HDEN RS16355
gene id: 582899:HDEN_RS16355
uniprot id: D8JWZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

582899:HDEN RS08260
gene id: 582899:HDEN_RS08260
uniprot id: D8JYN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

582899:HDEN RS02730
gene id: 582899:HDEN_RS02730
uniprot id: D8JSB9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

582899:HDEN RS15700
gene id: 582899:HDEN_RS15700
uniprot id: D8JW91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

582899:HDEN RS14375
gene id: 582899:HDEN_RS14375
uniprot id: D8JUS2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

582899:HDEN RS07355
gene id: 582899:HDEN_RS07355
uniprot id: D8JXU3
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

582899:HDEN RS04750
gene id: 582899:HDEN_RS04750
uniprot id: D8JUW3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

582899:HDEN RS13745
gene id: 582899:HDEN_RS13745
uniprot id: D8JU28
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

582899:HDEN RS04290
gene id: 582899:HDEN_RS04290
uniprot id: D8JU99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

582899:HDEN RS02845
gene id: 582899:HDEN_RS02845
uniprot id: D8JSR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Membrane

582899:HDEN RS06820
gene id: 582899:HDEN_RS06820
uniprot id: D8JX59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

582899:HDEN RS04725
gene id: 582899:HDEN_RS04725
uniprot id: D8JUV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS17310
gene id: 582899:HDEN_RS17310
uniprot id: D8JY81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

582899:HDEN RS02765
gene id: 582899:HDEN_RS02765
uniprot id: D8JSC6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS12525
gene id: 582899:HDEN_RS12525
uniprot id: D8JSP2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

582899:HDEN RS11725
gene id: 582899:HDEN_RS11725
uniprot id: D8JRV4
names: Subcellular Location Annotation
messages: Cytoplasm

582899:HDEN RS10820
gene id: 582899:HDEN_RS10820
uniprot id: D8JR07
names: Similarity
messages: Belongs to the YjdM family.

582899:HDEN RS01170
gene id: 582899:HDEN_RS01170
uniprot id: D8JQR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS07370
gene id: 582899:HDEN_RS07370
uniprot id: D8JXU6
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

582899:HDEN RS14155
gene id: 582899:HDEN_RS14155
uniprot id: D8JUM9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

582899:HDEN RS09935
gene id: 582899:HDEN_RS09935
uniprot id: D8JPT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

582899:HDEN RS15730
gene id: 582899:HDEN_RS15730
uniprot id: D8JW97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

582899:HDEN RS08355
gene id: 582899:HDEN_RS08355
uniprot id: D8JYQ5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS15775
gene id: 582899:HDEN_RS15775
uniprot id: D8JWM7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

582899:HDEN RS12390
gene id: 582899:HDEN_RS12390
uniprot id: D8JSL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

582899:HDEN RS16415
gene id: 582899:HDEN_RS16415
uniprot id: D8JXD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

582899:HDEN RS04070
gene id: 582899:HDEN_RS04070
uniprot id: D8JU57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

582899:HDEN RS16215
gene id: 582899:HDEN_RS16215
uniprot id: D8JWW4
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

582899:HDEN RS14560
gene id: 582899:HDEN_RS14560
uniprot id: D8JV86
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

582899:HDEN RS15770
gene id: 582899:HDEN_RS15770
uniprot id: D8JWM6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

582899:HDEN RS15160
gene id: 582899:HDEN_RS15160
uniprot id: D8JVY3
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

582899:HDEN RS13430
gene id: 582899:HDEN_RS13430
uniprot id: D8JTW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

582899:HDEN RS00290
gene id: 582899:HDEN_RS00290
uniprot id: D8JPJ3
names: Similarity
messages: Belongs to the YkuD family.

582899:HDEN RS17595
gene id: 582899:HDEN_RS17595
uniprot id: D8JYD2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

582899:HDEN RS04055
gene id: 582899:HDEN_RS04055
uniprot id: D8JTT2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS08395
gene id: 582899:HDEN_RS08395
uniprot id: D8JYR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

582899:HDEN RS05020
gene id: 582899:HDEN_RS05020
uniprot id: D8JV15
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

582899:HDEN RS16840
gene id: 582899:HDEN_RS16840
uniprot id: D8JXL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

582899:HDEN RS05170
gene id: 582899:HDEN_RS05170
uniprot id: D8JV45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

582899:HDEN RS15215
gene id: 582899:HDEN_RS15215
uniprot id: D8JVZ4
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

582899:HDEN RS02630
gene id: 582899:HDEN_RS02630
uniprot id: D8JQA0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

582899:HDEN RS05260
gene id: 582899:HDEN_RS05260
uniprot id: D8JV61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

582899:HDEN RS09380
gene id: 582899:HDEN_RS09380
uniprot id: D8JZA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

582899:HDEN RS17465
gene id: 582899:HDEN_RS17465
uniprot id: D8JYB1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

582899:HDEN RS11935
gene id: 582899:HDEN_RS11935
uniprot id: D8JRZ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

582899:HDEN RS10410
gene id: 582899:HDEN_RS10410
uniprot id: D8JQF6
names: Similarity
messages: Belongs to the BolA/IbaG family.

582899:HDEN RS14255
gene id: 582899:HDEN_RS14255
uniprot id: D8JUP9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

582899:HDEN RS03310
gene id: 582899:HDEN_RS03310
uniprot id: D8JT16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS02280
gene id: 582899:HDEN_RS02280
uniprot id: D8JS26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

582899:HDEN RS01430
gene id: 582899:HDEN_RS01430
uniprot id: D8JQX0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS16615
gene id: 582899:HDEN_RS16615
uniprot id: D8JXH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

582899:HDEN RS13485
gene id: 582899:HDEN_RS13485
uniprot id: D8JTX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

582899:HDEN RS15100
gene id: 582899:HDEN_RS15100
uniprot id: D8JVJ6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

582899:HDEN RS13575
gene id: 582899:HDEN_RS13575
uniprot id: D8JTZ4
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS06710
gene id: 582899:HDEN_RS06710
uniprot id: D8JX37
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

582899:HDEN RS15290
gene id: 582899:HDEN_RS15290
uniprot id: D8JW10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

582899:HDEN RS11575
gene id: 582899:HDEN_RS11575
uniprot id: D8JRS4
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

582899:HDEN RS10040
gene id: 582899:HDEN_RS10040
uniprot id: D8JPV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

582899:HDEN RS10280
gene id: 582899:HDEN_RS10280
uniprot id: D8JQD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

582899:HDEN RS13290
gene id: 582899:HDEN_RS13290
uniprot id: D8JTT9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

582899:HDEN RS13000
gene id: 582899:HDEN_RS13000
uniprot id: D8JTB3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

582899:HDEN RS11940
gene id: 582899:HDEN_RS11940
uniprot id: D8JRZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

582899:HDEN RS02945
gene id: 582899:HDEN_RS02945
uniprot id: D8JST8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

582899:HDEN RS10940
gene id: 582899:HDEN_RS10940
uniprot id: D8JR33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

582899:HDEN RS12205
gene id: 582899:HDEN_RS12205
uniprot id: D8JSH6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

582899:HDEN RS15500
gene id: 582899:HDEN_RS15500
uniprot id: D8JW52
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

582899:HDEN RS15300
gene id: 582899:HDEN_RS15300
uniprot id: D8JW12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

582899:HDEN RS11220
gene id: 582899:HDEN_RS11220
uniprot id: D8JR89
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

582899:HDEN RS01830
gene id: 582899:HDEN_RS01830
uniprot id: D8JRH0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

582899:HDEN RS17390
gene id: 582899:HDEN_RS17390
uniprot id: D8JY97
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

582899:HDEN RS16735
gene id: 582899:HDEN_RS16735
uniprot id: D8JXJ5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

582899:HDEN RS07140
gene id: 582899:HDEN_RS07140
uniprot id: D8JXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

582899:HDEN RS12005
gene id: 582899:HDEN_RS12005
uniprot id: D8JS12
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

582899:HDEN RS11315
gene id: 582899:HDEN_RS11315
uniprot id: D8JRA8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS16275
gene id: 582899:HDEN_RS16275
uniprot id: D8JWX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

582899:HDEN RS02545
gene id: 582899:HDEN_RS02545
uniprot id: D8JS80
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

582899:HDEN RS12665
gene id: 582899:HDEN_RS12665
uniprot id: D8JT46
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

582899:HDEN RS00295
gene id: 582899:HDEN_RS00295
uniprot id: D8JPJ4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

582899:HDEN RS03140
gene id: 582899:HDEN_RS03140
uniprot id: D8JSX9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

582899:HDEN RS15320
gene id: 582899:HDEN_RS15320
uniprot id: D8JW16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

582899:HDEN RS04960
gene id: 582899:HDEN_RS04960
uniprot id: D8JV03
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

582899:HDEN RS09115
gene id: 582899:HDEN_RS09115
uniprot id: D8JZ57
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

582899:HDEN RS10625
gene id: 582899:HDEN_RS10625
uniprot id: D8JQJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

582899:HDEN RS09525
gene id: 582899:HDEN_RS09525
uniprot id: D8JZD5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

582899:HDEN RS15330
gene id: 582899:HDEN_RS15330
uniprot id: D8JW18
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

582899:HDEN RS13190
gene id: 582899:HDEN_RS13190
uniprot id: D8JTE9
names: Similarity
messages: Belongs to the hyi family.

582899:HDEN RS13750
gene id: 582899:HDEN_RS13750
uniprot id: D8JU29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

582899:HDEN RS09770
gene id: 582899:HDEN_RS09770
uniprot id: D8JPP9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

582899:HDEN RS02785
gene id: 582899:HDEN_RS02785
uniprot id: D8JSD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

582899:HDEN RS01835
gene id: 582899:HDEN_RS01835
uniprot id: D8JRH1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

582899:HDEN RS17330
gene id: 582899:HDEN_RS17330
uniprot id: D8JY85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

582899:HDEN RS15350
gene id: 582899:HDEN_RS15350
uniprot id: D8JW22
names: Similarity
messages: Belongs to the type III secretion exporter family.

582899:HDEN RS00130
gene id: 582899:HDEN_RS00130
uniprot id: D8JPG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

582899:HDEN RS08015
gene id: 582899:HDEN_RS08015
uniprot id: D8JYI8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

582899:HDEN RS09795
gene id: 582899:HDEN_RS09795
uniprot id: D8JPQ4
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

582899:HDEN RS13045
gene id: 582899:HDEN_RS13045
uniprot id: D8JTC2
names: Similarity
messages: Belongs to the pyruvate kinase family.

582899:HDEN RS13345
gene id: 582899:HDEN_RS13345
uniprot id: D8JTV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

582899:HDEN RS16745
gene id: 582899:HDEN_RS16745
uniprot id: D8JXJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

582899:HDEN RS11600
gene id: 582899:HDEN_RS11600
uniprot id: D8JRS9
names: Similarity
messages: Belongs to the DEAD box helicase family.

582899:HDEN RS11640
gene id: 582899:HDEN_RS11640
uniprot id: D8JRT7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

582899:HDEN RS06390
gene id: 582899:HDEN_RS06390
uniprot id: D8JWJ6
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS01360
gene id: 582899:HDEN_RS01360
uniprot id: D8JQV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

582899:HDEN RS04380
gene id: 582899:HDEN_RS04380
uniprot id: D8JUB7
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

582899:HDEN RS07275
gene id: 582899:HDEN_RS07275
uniprot id: D8JXS6
names: Similarity
messages: Belongs to the HisA/HisF family.

582899:HDEN RS03150
gene id: 582899:HDEN_RS03150
uniprot id: D8JSY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

582899:HDEN RS02450
gene id: 582899:HDEN_RS02450
uniprot id: D8JS61
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS12780
gene id: 582899:HDEN_RS12780
uniprot id: D8JT68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

582899:HDEN RS16815
gene id: 582899:HDEN_RS16815
uniprot id: D8JXL1
names: Similarity
messages: Belongs to the UPF0102 family.

582899:HDEN RS01225
gene id: 582899:HDEN_RS01225
uniprot id: D8JQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

582899:HDEN RS13730
gene id: 582899:HDEN_RS13730
uniprot id: D8JU25
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

582899:HDEN RS00410
gene id: 582899:HDEN_RS00410
uniprot id: D8JPL7
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS13760
gene id: 582899:HDEN_RS13760
uniprot id: D8JU31
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

582899:HDEN RS07330
gene id: 582899:HDEN_RS07330
uniprot id: D8JXT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

582899:HDEN RS16115
gene id: 582899:HDEN_RS16115
uniprot id: D8JWU4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS17275
gene id: 582899:HDEN_RS17275
uniprot id: D8JY74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

582899:HDEN RS16850
gene id: 582899:HDEN_RS16850
uniprot id: D8JXL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

582899:HDEN RS09530
gene id: 582899:HDEN_RS09530
uniprot id: D8JZD6
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

582899:HDEN RS02580
gene id: 582899:HDEN_RS02580
uniprot id: D8JS87
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

582899:HDEN RS10125
gene id: 582899:HDEN_RS10125
uniprot id: D8JPW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

582899:HDEN RS00930
gene id: 582899:HDEN_RS00930
uniprot id: D8JQA1
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

582899:HDEN RS14185
gene id: 582899:HDEN_RS14185
uniprot id: D8JUN5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

582899:HDEN RS05025
gene id: 582899:HDEN_RS05025
uniprot id: D8JV16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

582899:HDEN RS03620
gene id: 582899:HDEN_RS03620
uniprot id: D8JTK0
names: Similarity
messages: Belongs to the selenium-binding protein family.

582899:HDEN RS13530
gene id: 582899:HDEN_RS13530
uniprot id: D8JTY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

582899:HDEN RS01420
gene id: 582899:HDEN_RS01420
uniprot id: D8JQW8
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

582899:HDEN RS09360
gene id: 582899:HDEN_RS09360
uniprot id: D8JZA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

582899:HDEN RS07025
gene id: 582899:HDEN_RS07025
uniprot id: D8JXA0
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

582899:HDEN RS14110
gene id: 582899:HDEN_RS14110
uniprot id: D8JUM0
names: Similarity
messages: Belongs to the DinB family.

582899:HDEN RS12055
gene id: 582899:HDEN_RS12055
uniprot id: D8JSE6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

582899:HDEN RS16360
gene id: 582899:HDEN_RS16360
uniprot id: D8JWZ3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

582899:HDEN RS09750
gene id: 582899:HDEN_RS09750
uniprot id: D8JPP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

582899:HDEN RS10460
gene id: 582899:HDEN_RS10460
uniprot id: D8JQG6
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

582899:HDEN RS13240
gene id: 582899:HDEN_RS13240
uniprot id: D8JTF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

582899:HDEN RS07960
gene id: 582899:HDEN_RS07960
uniprot id: D8JYH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

582899:HDEN RS00060
gene id: 582899:HDEN_RS00060
uniprot id: D8JPE8
names: Similarity
messages: Belongs to the SCO1/2 family.

582899:HDEN RS12750
gene id: 582899:HDEN_RS12750
uniprot id: D8JT62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

582899:HDEN RS11625
gene id: 582899:HDEN_RS11625
uniprot id: D8JRT4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

582899:HDEN RS16755
gene id: 582899:HDEN_RS16755
uniprot id: D8JXJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

582899:HDEN RS14180
gene id: 582899:HDEN_RS14180
uniprot id: D8JUN4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

582899:HDEN RS13525
gene id: 582899:HDEN_RS13525
uniprot id: D8JTY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

582899:HDEN RS13895
gene id: 582899:HDEN_RS13895
uniprot id: D8JUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

582899:HDEN RS02250
gene id: 582899:HDEN_RS02250
uniprot id: D8JS20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

582899:HDEN RS01010
gene id: 582899:HDEN_RS01010
uniprot id: D8JQB6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

582899:HDEN RS02055
gene id: 582899:HDEN_RS02055
uniprot id: D8JRL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

582899:HDEN RS04535
gene id: 582899:HDEN_RS04535
uniprot id: D8JUE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

582899:HDEN RS17370
gene id: 582899:HDEN_RS17370
uniprot id: D8JY93
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

582899:HDEN RS01800
gene id: 582899:HDEN_RS01800
uniprot id: D8JRG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

582899:HDEN RS16725
gene id: 582899:HDEN_RS16725
uniprot id: D8JXJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

582899:HDEN RS13465
gene id: 582899:HDEN_RS13465
uniprot id: D8JTX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

582899:HDEN RS05415
gene id: 582899:HDEN_RS05415
uniprot id: D8JVL8
names: Similarity
messages: Belongs to the ros/MucR family.

582899:HDEN RS06795
gene id: 582899:HDEN_RS06795
uniprot id: D8JX54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

582899:HDEN RS07085
gene id: 582899:HDEN_RS07085
uniprot id: D8JXB2
names: Similarity
messages: Belongs to the Gfa family.

582899:HDEN RS02530
gene id: 582899:HDEN_RS02530
uniprot id: D8JS77
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

582899:HDEN RS10260
gene id: 582899:HDEN_RS10260
uniprot id: D8JQC6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

582899:HDEN RS09475
gene id: 582899:HDEN_RS09475
uniprot id: D8JZC5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

582899:HDEN RS01145
gene id: 582899:HDEN_RS01145
uniprot id: D8JQR1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS14380
gene id: 582899:HDEN_RS14380
uniprot id: D8JUS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

582899:HDEN RS11655
gene id: 582899:HDEN_RS11655
uniprot id: D8JRU0
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

582899:HDEN RS16190
gene id: 582899:HDEN_RS16190
uniprot id: D8JWV9
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

582899:HDEN RS16405
gene id: 582899:HDEN_RS16405
uniprot id: D8JXC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

582899:HDEN RS15970
gene id: 582899:HDEN_RS15970
uniprot id: D8JWR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

582899:HDEN RS05145
gene id: 582899:HDEN_RS05145
uniprot id: D8JV40
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

582899:HDEN RS13200
gene id: 582899:HDEN_RS13200
uniprot id: D8JTF1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS04045
gene id: 582899:HDEN_RS04045
uniprot id: D8JTT0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

582899:HDEN RS15590
gene id: 582899:HDEN_RS15590
uniprot id: D8JW69
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

582899:HDEN RS10010
gene id: 582899:HDEN_RS10010
uniprot id: D8JPU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

582899:HDEN RS04205
gene id: 582899:HDEN_RS04205
uniprot id: D8JU83
names: Similarity
messages: Belongs to the YfgM family.

582899:HDEN RS11560
gene id: 582899:HDEN_RS11560
uniprot id: D8JRS1
names: Similarity
messages: Belongs to the ArsC family.

582899:HDEN RS16005
gene id: 582899:HDEN_RS16005
uniprot id: D8JWS1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

582899:HDEN RS06160
gene id: 582899:HDEN_RS06160
uniprot id: D8JWE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

582899:HDEN RS13490
gene id: 582899:HDEN_RS13490
uniprot id: D8JTX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

582899:HDEN RS17085
gene id: 582899:HDEN_RS17085
uniprot id: D8JY37
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

582899:HDEN RS11765
gene id: 582899:HDEN_RS11765
uniprot id: D8JRW2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

582899:HDEN RS03700
gene id: 582899:HDEN_RS03700
uniprot id: D8JTL5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

582899:HDEN RS16855
gene id: 582899:HDEN_RS16855
uniprot id: D8JXL9
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

582899:HDEN RS12420
gene id: 582899:HDEN_RS12420
uniprot id: D8JSM0
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

582899:HDEN RS16395
gene id: 582899:HDEN_RS16395
uniprot id: D8JXC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

582899:HDEN RS07165
gene id: 582899:HDEN_RS07165
uniprot id: D8JXQ6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS12835
gene id: 582899:HDEN_RS12835
uniprot id: D8JT79
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

582899:HDEN RS05240
gene id: 582899:HDEN_RS05240
uniprot id: D8JV57
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

582899:HDEN RS17790
gene id: 582899:HDEN_RS17790
uniprot id: D8JT65
names: Function
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

582899:HDEN RS01205
gene id: 582899:HDEN_RS01205
uniprot id: D8JQS3
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

582899:HDEN RS08625
gene id: 582899:HDEN_RS08625
uniprot id: D8JYV6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS14775
gene id: 582899:HDEN_RS14775
uniprot id: D8JVD0
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS13340
gene id: 582899:HDEN_RS13340
uniprot id: D8JTU9
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

582899:HDEN RS01555
gene id: 582899:HDEN_RS01555
uniprot id: D8JQZ5
names: Similarity
messages: Belongs to the GSP E family.

582899:HDEN RS12830
gene id: 582899:HDEN_RS12830
uniprot id: D8JT78
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

582899:HDEN RS02825
gene id: 582899:HDEN_RS02825
uniprot id: D8JSD8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

582899:HDEN RS09060
gene id: 582899:HDEN_RS09060
uniprot id: D8JZ46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

582899:HDEN RS11430
gene id: 582899:HDEN_RS11430
uniprot id: D8JRP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

582899:HDEN RS06370
gene id: 582899:HDEN_RS06370
uniprot id: D8JWJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

582899:HDEN RS08385
gene id: 582899:HDEN_RS08385
uniprot id: D8JYR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

582899:HDEN RS16930
gene id: 582899:HDEN_RS16930
uniprot id: D8JXN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

582899:HDEN RS03115
gene id: 582899:HDEN_RS03115
uniprot id: D8JSX4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

582899:HDEN RS05595
gene id: 582899:HDEN_RS05595
uniprot id: D8JVQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

582899:HDEN RS15860
gene id: 582899:HDEN_RS15860
uniprot id: D8JWP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

582899:HDEN RS09105
gene id: 582899:HDEN_RS09105
uniprot id: D8JZ54
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

582899:HDEN RS15455
gene id: 582899:HDEN_RS15455
uniprot id: D8JW43
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

582899:HDEN RS17185
gene id: 582899:HDEN_RS17185
uniprot id: D8JY56
names: Similarity
messages: Belongs to the thioredoxin family.

582899:HDEN RS11500
gene id: 582899:HDEN_RS11500
uniprot id: D8JRR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

582899:HDEN RS16370
gene id: 582899:HDEN_RS16370
uniprot id: D8JWZ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

582899:HDEN RS03975
gene id: 582899:HDEN_RS03975
uniprot id: D8JTR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

582899:HDEN RS13195
gene id: 582899:HDEN_RS13195
uniprot id: D8JTF0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

582899:HDEN RS13355
gene id: 582899:HDEN_RS13355
uniprot id: D8JTV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

582899:HDEN RS01580
gene id: 582899:HDEN_RS01580
uniprot id: D8JR00
names: Similarity
messages: Belongs to the peptidase C40 family.

582899:HDEN RS16830
gene id: 582899:HDEN_RS16830
uniprot id: D8JXL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

582899:HDEN RS05175
gene id: 582899:HDEN_RS05175
uniprot id: D8JV46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

582899:HDEN RS16045
gene id: 582899:HDEN_RS16045
uniprot id: D8JWS9
names: Similarity
messages: Belongs to the ArsC family.

582899:HDEN RS02475
gene id: 582899:HDEN_RS02475
uniprot id: D8JS66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

582899:HDEN RS11415
gene id: 582899:HDEN_RS11415
uniprot id: D8JRC8
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

582899:HDEN RS01095
gene id: 582899:HDEN_RS01095
uniprot id: D8JQQ1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

582899:HDEN RS14340
gene id: 582899:HDEN_RS14340
uniprot id: D8JUR5
names: Similarity
messages: Belongs to the peptidase M16 family.

582899:HDEN RS17300
gene id: 582899:HDEN_RS17300
uniprot id: D8JY79
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS04410
gene id: 582899:HDEN_RS04410
uniprot id: D8JUC3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

582899:HDEN RS07450
gene id: 582899:HDEN_RS07450
uniprot id: D8JXW2
names: Similarity
messages: Belongs to the FrmR/RcnR family.

582899:HDEN RS13740
gene id: 582899:HDEN_RS13740
uniprot id: D8JU27
names: Similarity
messages: Belongs to the FMO family.

582899:HDEN RS04790
gene id: 582899:HDEN_RS04790
uniprot id: D8JUX1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

582899:HDEN RS17080
gene id: 582899:HDEN_RS17080
uniprot id: D8JY36
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

582899:HDEN RS15745
gene id: 582899:HDEN_RS15745
uniprot id: D8JWA0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

582899:HDEN RS16155
gene id: 582899:HDEN_RS16155
uniprot id: D8JWV2
names: Similarity
messages: Belongs to the Tim44 family.

582899:HDEN RS04945
gene id: 582899:HDEN_RS04945
uniprot id: D8JV01
names: Similarity
messages: Belongs to the UPF0145 family.

582899:HDEN RS02230
gene id: 582899:HDEN_RS02230
uniprot id: D8JS17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS14130
gene id: 582899:HDEN_RS14130
uniprot id: D8JUM4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS12025
gene id: 582899:HDEN_RS12025
uniprot id: D8JSE0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

582899:HDEN RS01330
gene id: 582899:HDEN_RS01330
uniprot id: D8JQU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

582899:HDEN RS16380
gene id: 582899:HDEN_RS16380
uniprot id: D8JWZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

582899:HDEN RS05075
gene id: 582899:HDEN_RS05075
uniprot id: D8JV26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

582899:HDEN RS09515
gene id: 582899:HDEN_RS09515
uniprot id: D8JZD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

582899:HDEN RS02820
gene id: 582899:HDEN_RS02820
uniprot id: D8JSD7
names: Similarity
messages: Belongs to the UPF0423 family.

582899:HDEN RS14100
gene id: 582899:HDEN_RS14100
uniprot id: D8JUL8
names: Similarity
messages: Belongs to the cytochrome P450 family.

582899:HDEN RS16675
gene id: 582899:HDEN_RS16675
uniprot id: D8JXI3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

582899:HDEN RS08715
gene id: 582899:HDEN_RS08715
uniprot id: D8JYX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

582899:HDEN RS10535
gene id: 582899:HDEN_RS10535
uniprot id: D8JQI1
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS16245
gene id: 582899:HDEN_RS16245
uniprot id: D8JWX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

582899:HDEN RS03260
gene id: 582899:HDEN_RS03260
uniprot id: D8JT05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

582899:HDEN RS13135
gene id: 582899:HDEN_RS13135
uniprot id: D8JTD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

582899:HDEN RS05470
gene id: 582899:HDEN_RS05470
uniprot id: D8JVM8
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

582899:HDEN RS13805
gene id: 582899:HDEN_RS13805
uniprot id: D8JU41
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

582899:HDEN RS13595
gene id: 582899:HDEN_RS13595
uniprot id: D8JTZ8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

582899:HDEN RS14385
gene id: 582899:HDEN_RS14385
uniprot id: D8JUS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

582899:HDEN RS15105
gene id: 582899:HDEN_RS15105
uniprot id: D8JVJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

582899:HDEN RS14360
gene id: 582899:HDEN_RS14360
uniprot id: D8JUR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

582899:HDEN RS08695
gene id: 582899:HDEN_RS08695
uniprot id: D8JYX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

582899:HDEN RS15240
gene id: 582899:HDEN_RS15240
uniprot id: D8JVZ9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

582899:HDEN RS07980
gene id: 582899:HDEN_RS07980
uniprot id: D8JYI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

582899:HDEN RS12860
gene id: 582899:HDEN_RS12860
uniprot id: D8JT84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

582899:HDEN RS12015
gene id: 582899:HDEN_RS12015
uniprot id: D8JS14
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

582899:HDEN RS03400
gene id: 582899:HDEN_RS03400
uniprot id: D8JT34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS07345
gene id: 582899:HDEN_RS07345
uniprot id: D8JXU0
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

582899:HDEN RS13450
gene id: 582899:HDEN_RS13450
uniprot id: D8JTW9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS00520
gene id: 582899:HDEN_RS00520
uniprot id: D8JQ10
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

582899:HDEN RS06695
gene id: 582899:HDEN_RS06695
uniprot id: D8JX34
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

582899:HDEN RS09355
gene id: 582899:HDEN_RS09355
uniprot id: D8JZA1
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS16135
gene id: 582899:HDEN_RS16135
uniprot id: D8JWU8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

582899:HDEN RS14145
gene id: 582899:HDEN_RS14145
uniprot id: D8JUM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

582899:HDEN RS00100
gene id: 582899:HDEN_RS00100
uniprot id: D8JPF6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

582899:HDEN RS03125
gene id: 582899:HDEN_RS03125
uniprot id: D8JSX6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.
messages: Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).

582899:HDEN RS16560
gene id: 582899:HDEN_RS16560
uniprot id: D8JXG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

582899:HDEN RS10720
gene id: 582899:HDEN_RS10720
uniprot id: D8JQL7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

582899:HDEN RS07395
gene id: 582899:HDEN_RS07395
uniprot id: D8JXV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

582899:HDEN RS01160
gene id: 582899:HDEN_RS01160
uniprot id: D8JQR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

582899:HDEN RS16945
gene id: 582899:HDEN_RS16945
uniprot id: D8JXN6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

582899:HDEN RS09010
gene id: 582899:HDEN_RS09010
uniprot id: D8JZ35
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

582899:HDEN RS07435
gene id: 582899:HDEN_RS07435
uniprot id: D8JXV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

582899:HDEN RS09650
gene id: 582899:HDEN_RS09650
uniprot id: D8JPM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

582899:HDEN RS06920
gene id: 582899:HDEN_RS06920
uniprot id: D8JX79
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

582899:HDEN RS13800
gene id: 582899:HDEN_RS13800
uniprot id: D8JU40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

582899:HDEN RS15235
gene id: 582899:HDEN_RS15235
uniprot id: D8JVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

582899:HDEN RS12155
gene id: 582899:HDEN_RS12155
uniprot id: D8JSG7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

582899:HDEN RS02995
gene id: 582899:HDEN_RS02995
uniprot id: D8JSU9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS09460
gene id: 582899:HDEN_RS09460
uniprot id: D8JZC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

582899:HDEN RS10635
gene id: 582899:HDEN_RS10635
uniprot id: D8JQK1
names: Similarity
messages: Belongs to the bacterial secretin family. GSP D subfamily.

582899:HDEN RS05115
gene id: 582899:HDEN_RS05115
uniprot id: D8JV34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

582899:HDEN RS09715
gene id: 582899:HDEN_RS09715
uniprot id: D8JPN7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

582899:HDEN RS01665
gene id: 582899:HDEN_RS01665
uniprot id: D8JRE0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

582899:HDEN RS04575
gene id: 582899:HDEN_RS04575
uniprot id: D8JUF3
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS10530
gene id: 582899:HDEN_RS10530
uniprot id: D8JQI0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

582899:HDEN RS04870
gene id: 582899:HDEN_RS04870
uniprot id: D8JUY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

582899:HDEN RS15390
gene id: 582899:HDEN_RS15390
uniprot id: D8JW29
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

582899:HDEN RS08365
gene id: 582899:HDEN_RS08365
uniprot id: D8JYQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS13120
gene id: 582899:HDEN_RS13120
uniprot id: D8JTD5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

582899:HDEN RS08935
gene id: 582899:HDEN_RS08935
uniprot id: D8JZ21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

582899:HDEN RS08685
gene id: 582899:HDEN_RS08685
uniprot id: D8JYW9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

582899:HDEN RS13810
gene id: 582899:HDEN_RS13810
uniprot id: D8JU42
names: Similarity
messages: Belongs to the GcvT family.

582899:HDEN RS00205
gene id: 582899:HDEN_RS00205
uniprot id: D8JPH6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

582899:HDEN RS08825
gene id: 582899:HDEN_RS08825
uniprot id: D8JYZ8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

582899:HDEN RS13205
gene id: 582899:HDEN_RS13205
uniprot id: D8JTF2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

582899:HDEN RS11955
gene id: 582899:HDEN_RS11955
uniprot id: D8JS02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

582899:HDEN RS13695
gene id: 582899:HDEN_RS13695
uniprot id: D8JU18
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

582899:HDEN RS12485
gene id: 582899:HDEN_RS12485
uniprot id: D8JSN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

582899:HDEN RS16065
gene id: 582899:HDEN_RS16065
uniprot id: D8JWT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

582899:HDEN RS03685
gene id: 582899:HDEN_RS03685
uniprot id: D8JTL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

582899:HDEN RS12560
gene id: 582899:HDEN_RS12560
uniprot id: D8JSP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

582899:HDEN RS16240
gene id: 582899:HDEN_RS16240
uniprot id: D8JWW9
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

582899:HDEN RS04975
gene id: 582899:HDEN_RS04975
uniprot id: D8JV06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

582899:HDEN RS08515
gene id: 582899:HDEN_RS08515
uniprot id: D8JYT7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

582899:HDEN RS06410
gene id: 582899:HDEN_RS06410
uniprot id: D8JWJ9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

582899:HDEN RS00435
gene id: 582899:HDEN_RS00435
uniprot id: D8JPZ2
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

582899:HDEN RS07205
gene id: 582899:HDEN_RS07205
uniprot id: D8JXR2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS02640
gene id: 582899:HDEN_RS02640
uniprot id: D8JSA0
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS08510
gene id: 582899:HDEN_RS08510
uniprot id: D8JYT6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

582899:HDEN RS14470
gene id: 582899:HDEN_RS14470
uniprot id: D8JUU1
names: Function
messages: Acts on leucine, isoleucine and valine.

582899:HDEN RS03965
gene id: 582899:HDEN_RS03965
uniprot id: D8JTR5
names: Similarity
messages: Belongs to the citrate synthase family.

582899:HDEN RS12745
gene id: 582899:HDEN_RS12745
uniprot id: D8JT61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

582899:HDEN RS13620
gene id: 582899:HDEN_RS13620
uniprot id: D8JU03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

582899:HDEN RS08980
gene id: 582899:HDEN_RS08980
uniprot id: D8JZ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

582899:HDEN RS05045
gene id: 582899:HDEN_RS05045
uniprot id: D8JV20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

582899:HDEN RS00190
gene id: 582899:HDEN_RS00190
uniprot id: D8JPH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

582899:HDEN RS14280
gene id: 582899:HDEN_RS14280
uniprot id: D8JUQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

582899:HDEN RS15470
gene id: 582899:HDEN_RS15470
uniprot id: D8JW46
names: Similarity
messages: Belongs to the phosphoribulokinase family.

582899:HDEN RS03860
gene id: 582899:HDEN_RS03860
uniprot id: D8JTP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

582899:HDEN RS17135
gene id: 582899:HDEN_RS17135
uniprot id: D8JY47
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

582899:HDEN RS15675
gene id: 582899:HDEN_RS15675
uniprot id: D8JW85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

582899:HDEN RS07295
gene id: 582899:HDEN_RS07295
uniprot id: D8JXT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

582899:HDEN RS14415
gene id: 582899:HDEN_RS14415
uniprot id: D8JUT0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

582899:HDEN RS12770
gene id: 582899:HDEN_RS12770
uniprot id: D8JT66
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

582899:HDEN RS02340
gene id: 582899:HDEN_RS02340
uniprot id: D8JS39
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

582899:HDEN RS11105
gene id: 582899:HDEN_RS11105
uniprot id: D8JR65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

582899:HDEN RS09755
gene id: 582899:HDEN_RS09755
uniprot id: D8JPP6
names: Similarity
messages: Belongs to the histone deacetylase family.

582899:HDEN RS15800
gene id: 582899:HDEN_RS15800
uniprot id: D8JWN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS07520
gene id: 582899:HDEN_RS07520
uniprot id: D8JXX7
names: Similarity
messages: Belongs to the FBPase class 2 family.

582899:HDEN RS11915
gene id: 582899:HDEN_RS11915
uniprot id: D8JRZ2
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS11110
gene id: 582899:HDEN_RS11110
uniprot id: D8JR66
names: Similarity
messages: Belongs to the virb1 family.

582899:HDEN RS11250
gene id: 582899:HDEN_RS11250
uniprot id: D8JR96
names: Similarity
messages: Belongs to the CFA/CMAS family.

582899:HDEN RS15075
gene id: 582899:HDEN_RS15075
uniprot id: D8JVJ1
names: Similarity
messages: Belongs to the Dps family.

582899:HDEN RS09955
gene id: 582899:HDEN_RS09955
uniprot id: D8JPT6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

582899:HDEN RS07485
gene id: 582899:HDEN_RS07485
uniprot id: D8JXW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

582899:HDEN RS07935
gene id: 582899:HDEN_RS07935
uniprot id: D8JYH2
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

582899:HDEN RS09570
gene id: 582899:HDEN_RS09570
uniprot id: D8JZE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

582899:HDEN RS05390
gene id: 582899:HDEN_RS05390
uniprot id: D8JVL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS01390
gene id: 582899:HDEN_RS01390
uniprot id: D8JQW2
names: Similarity
messages: Belongs to the amidase family.

582899:HDEN RS08690
gene id: 582899:HDEN_RS08690
uniprot id: D8JYX0
names: Similarity
messages: Belongs to the Gfa family.

582899:HDEN RS06735
gene id: 582899:HDEN_RS06735
uniprot id: D8JX42
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

582899:HDEN RS04555
gene id: 582899:HDEN_RS04555
uniprot id: D8JUE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

582899:HDEN RS04735
gene id: 582899:HDEN_RS04735
uniprot id: D8JUW0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

582899:HDEN RS11300
gene id: 582899:HDEN_RS11300
uniprot id: D8JRA5
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS12455
gene id: 582899:HDEN_RS12455
uniprot id: D8JSM8
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

582899:HDEN RS05265
gene id: 582899:HDEN_RS05265
uniprot id: D8JV62
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS17475
gene id: 582899:HDEN_RS17475
uniprot id: D8JYB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

582899:HDEN RS10220
gene id: 582899:HDEN_RS10220
uniprot id: D8JQB9
names: Similarity
messages: Belongs to the PhzF family.

582899:HDEN RS02850
gene id: 582899:HDEN_RS02850
uniprot id: D8JSR9
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

582899:HDEN RS11390
gene id: 582899:HDEN_RS11390
uniprot id: D8JRC3
names: Similarity
messages: Belongs to the thioredoxin family.

582899:HDEN RS16880
gene id: 582899:HDEN_RS16880
uniprot id: D8JXM4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

582899:HDEN RS10355
gene id: 582899:HDEN_RS10355
uniprot id: D8JQE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

582899:HDEN RS14305
gene id: 582899:HDEN_RS14305
uniprot id: D8JUQ8
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

582899:HDEN RS09100
gene id: 582899:HDEN_RS09100
uniprot id: D8JZ53
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

582899:HDEN RS11810
gene id: 582899:HDEN_RS11810
uniprot id: D8JRX1
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

582899:HDEN RS09545
gene id: 582899:HDEN_RS09545
uniprot id: D8JZD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

582899:HDEN RS04230
gene id: 582899:HDEN_RS04230
uniprot id: D8JU88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

582899:HDEN RS13660
gene id: 582899:HDEN_RS13660
uniprot id: D8JU11
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

582899:HDEN RS11075
gene id: 582899:HDEN_RS11075
uniprot id: D8JR59
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

582899:HDEN RS12160
gene id: 582899:HDEN_RS12160
uniprot id: D8JSG8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

582899:HDEN RS08470
gene id: 582899:HDEN_RS08470
uniprot id: D8JYS8
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS13085
gene id: 582899:HDEN_RS13085
uniprot id: D8JTC9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

582899:HDEN RS03805
gene id: 582899:HDEN_RS03805
uniprot id: D8JTN4
names: Similarity
messages: Belongs to the glutamate synthase family.

582899:HDEN RS04720
gene id: 582899:HDEN_RS04720
uniprot id: D8JUV7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

582899:HDEN RS12360
gene id: 582899:HDEN_RS12360
uniprot id: D8JSK8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

582899:HDEN RS13020
gene id: 582899:HDEN_RS13020
uniprot id: D8JTB7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

582899:HDEN RS09510
gene id: 582899:HDEN_RS09510
uniprot id: D8JZD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

582899:HDEN RS10415
gene id: 582899:HDEN_RS10415
uniprot id: D8JQF7
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

582899:HDEN RS11595
gene id: 582899:HDEN_RS11595
uniprot id: D8JRS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

582899:HDEN RS03435
gene id: 582899:HDEN_RS03435
uniprot id: D8JTG4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

582899:HDEN RS09870
gene id: 582899:HDEN_RS09870
uniprot id: D8JPR9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

582899:HDEN RS02540
gene id: 582899:HDEN_RS02540
uniprot id: D8JS79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

582899:HDEN RS15155
gene id: 582899:HDEN_RS15155
uniprot id: D8JVY2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

582899:HDEN RS12640
gene id: 582899:HDEN_RS12640
uniprot id: D8JT41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

582899:HDEN RS01875
gene id: 582899:HDEN_RS01875
uniprot id: D8JRH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

582899:HDEN RS03420
gene id: 582899:HDEN_RS03420
uniprot id: D8JT38
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

582899:HDEN RS11630
gene id: 582899:HDEN_RS11630
uniprot id: D8JRT5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

582899:HDEN RS06140
gene id: 582899:HDEN_RS06140
uniprot id: D8JWE5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

582899:HDEN RS14435
gene id: 582899:HDEN_RS14435
uniprot id: D8JUT4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

582899:HDEN RS11360
gene id: 582899:HDEN_RS11360
uniprot id: D8JRB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

582899:HDEN RS12470
gene id: 582899:HDEN_RS12470
uniprot id: D8JSN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

582899:HDEN RS12075
gene id: 582899:HDEN_RS12075
uniprot id: D8JSF0
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

582899:HDEN RS03960
gene id: 582899:HDEN_RS03960
uniprot id: D8JTR4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

582899:HDEN RS04405
gene id: 582899:HDEN_RS04405
uniprot id: D8JUC2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

582899:HDEN RS08900
gene id: 582899:HDEN_RS08900
uniprot id: D8JZ14
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS17405
gene id: 582899:HDEN_RS17405
uniprot id: D8JYA0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

582899:HDEN RS15315
gene id: 582899:HDEN_RS15315
uniprot id: D8JW15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

582899:HDEN RS10085
gene id: 582899:HDEN_RS10085
uniprot id: D8JPW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

582899:HDEN RS08280
gene id: 582899:HDEN_RS08280
uniprot id: D8JYP0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

582899:HDEN RS06365
gene id: 582899:HDEN_RS06365
uniprot id: D8JWJ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

582899:HDEN RS01825
gene id: 582899:HDEN_RS01825
uniprot id: D8JRG9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

582899:HDEN RS06300
gene id: 582899:HDEN_RS06300
uniprot id: D8JWH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell inner membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

582899:HDEN RS01840
gene id: 582899:HDEN_RS01840
uniprot id: D8JRH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

582899:HDEN RS15810
gene id: 582899:HDEN_RS15810
uniprot id: D8JWN4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. BioZ family.
messages: Involved in the formation of the biotin precursor pimeloyl-ACP. Catalyzes the condensation of glutaryl-CoA, an intermediate in lysine degradation, with malonyl-ACP to produce 3-oxopimeloyl-ACP.

582899:HDEN RS12575
gene id: 582899:HDEN_RS12575
uniprot id: D8JSQ2
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS04235
gene id: 582899:HDEN_RS04235
uniprot id: D8JU89
names: Subcellular Location Annotation
messages: Cytoplasm

582899:HDEN RS05475
gene id: 582899:HDEN_RS05475
uniprot id: D8JVM9
names: Similarity
messages: Belongs to the UPF0260 family.

582899:HDEN RS02000
gene id: 582899:HDEN_RS02000
uniprot id: D8JRK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

582899:HDEN RS07400
gene id: 582899:HDEN_RS07400
uniprot id: D8JXV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

582899:HDEN RS01200
gene id: 582899:HDEN_RS01200
uniprot id: D8JQS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

582899:HDEN RS15325
gene id: 582899:HDEN_RS15325
uniprot id: D8JW17
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

582899:HDEN RS00955
gene id: 582899:HDEN_RS00955
uniprot id: D8JQA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

582899:HDEN RS12905
gene id: 582899:HDEN_RS12905
uniprot id: D8JT94
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

582899:HDEN RS16835
gene id: 582899:HDEN_RS16835
uniprot id: D8JXL5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

582899:HDEN RS01090
gene id: 582899:HDEN_RS01090
uniprot id: D8JQQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

582899:HDEN RS11060
gene id: 582899:HDEN_RS11060
uniprot id: D8JR56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

582899:HDEN RS12355
gene id: 582899:HDEN_RS12355
uniprot id: D8JSK7
names: Subcellular Location Annotation
messages: Mitochondrion

582899:HDEN RS09925
gene id: 582899:HDEN_RS09925
uniprot id: D8JPT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

582899:HDEN RS10265
gene id: 582899:HDEN_RS10265
uniprot id: D8JQC7
names: Similarity
messages: Belongs to the OprB family.

582899:HDEN RS02585
gene id: 582899:HDEN_RS02585
uniprot id: D8JS88
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS17100
gene id: 582899:HDEN_RS17100
uniprot id: D8JY40
names: Subcellular Location Annotation
messages: Nucleus

582899:HDEN RS09640
gene id: 582899:HDEN_RS09640
uniprot id: D8JPM3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

582899:HDEN RS15690
gene id: 582899:HDEN_RS15690
uniprot id: D8JW89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

582899:HDEN RS14115
gene id: 582899:HDEN_RS14115
uniprot id: D8JUM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

582899:HDEN RS11455
gene id: 582899:HDEN_RS11455
uniprot id: D8JRQ3
names: Similarity
messages: Belongs to the peptidase S49 family.

582899:HDEN RS11860
gene id: 582899:HDEN_RS11860
uniprot id: D8JRY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

582899:HDEN RS12095
gene id: 582899:HDEN_RS12095
uniprot id: D8JSF4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

582899:HDEN RS00380
gene id: 582899:HDEN_RS00380
uniprot id: D8JPL2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

582899:HDEN RS09985
gene id: 582899:HDEN_RS09985
uniprot id: D8JPU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

582899:HDEN RS04775
gene id: 582899:HDEN_RS04775
uniprot id: D8JUW8
names: Similarity
messages: Belongs to the AlaDH/PNT family.

582899:HDEN RS09230
gene id: 582899:HDEN_RS09230
uniprot id: D8JZ78
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

582899:HDEN RS09070
gene id: 582899:HDEN_RS09070
uniprot id: D8JZ48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

582899:HDEN RS07515
gene id: 582899:HDEN_RS07515
uniprot id: D8JXX6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

582899:HDEN RS05660
gene id: 582899:HDEN_RS05660
uniprot id: D8JVR6
names: Similarity
messages: Belongs to the peptidase M1 family.

582899:HDEN RS14315
gene id: 582899:HDEN_RS14315
uniprot id: D8JUR0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

582899:HDEN RS07990
gene id: 582899:HDEN_RS07990
uniprot id: D8JYI3
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS13320
gene id: 582899:HDEN_RS13320
uniprot id: D8JTU5
names: Similarity
messages: Belongs to the CobH/CbiC family.

582899:HDEN RS01750
gene id: 582899:HDEN_RS01750
uniprot id: D8JRF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

582899:HDEN RS11805
gene id: 582899:HDEN_RS11805
uniprot id: D8JRX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

582899:HDEN RS13535
gene id: 582899:HDEN_RS13535
uniprot id: D8JTY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

582899:HDEN RS07045
gene id: 582899:HDEN_RS07045
uniprot id: D8JXA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

582899:HDEN RS16230
gene id: 582899:HDEN_RS16230
uniprot id: D8JWW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

582899:HDEN RS05050
gene id: 582899:HDEN_RS05050
uniprot id: D8JV21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

582899:HDEN RS01055
gene id: 582899:HDEN_RS01055
uniprot id: D8JQP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

582899:HDEN RS01025
gene id: 582899:HDEN_RS01025
uniprot id: D8JQN8
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS08235
gene id: 582899:HDEN_RS08235
uniprot id: D8JYN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

582899:HDEN RS12150
gene id: 582899:HDEN_RS12150
uniprot id: D8JSG6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

582899:HDEN RS00945
gene id: 582899:HDEN_RS00945
uniprot id: D8JQA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

582899:HDEN RS01150
gene id: 582899:HDEN_RS01150
uniprot id: D8JQR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS12465
gene id: 582899:HDEN_RS12465
uniprot id: D8JSN0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

582899:HDEN RS13460
gene id: 582899:HDEN_RS13460
uniprot id: D8JTX1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

582899:HDEN RS04985
gene id: 582899:HDEN_RS04985
uniprot id: D8JV08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

582899:HDEN RS10945
gene id: 582899:HDEN_RS10945
uniprot id: D8JR34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

582899:HDEN RS06800
gene id: 582899:HDEN_RS06800
uniprot id: D8JX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

582899:HDEN RS08270
gene id: 582899:HDEN_RS08270
uniprot id: D8JYN8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

582899:HDEN RS16590
gene id: 582899:HDEN_RS16590
uniprot id: D8JXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

582899:HDEN RS05000
gene id: 582899:HDEN_RS05000
uniprot id: D8JV11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

582899:HDEN RS14235
gene id: 582899:HDEN_RS14235
uniprot id: D8JUP5
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

582899:HDEN RS07360
gene id: 582899:HDEN_RS07360
uniprot id: D8JXU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

582899:HDEN RS11435
gene id: 582899:HDEN_RS11435
uniprot id: D8JRP9
names: Similarity
messages: Belongs to the TrpF family.

582899:HDEN RS06360
gene id: 582899:HDEN_RS06360
uniprot id: D8JWJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

582899:HDEN RS02390
gene id: 582899:HDEN_RS02390
uniprot id: D8JS49
names: Subcellular Location Annotation
messages: Membrane

582899:HDEN RS12070
gene id: 582899:HDEN_RS12070
uniprot id: D8JSE9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

582899:HDEN RS15305
gene id: 582899:HDEN_RS15305
uniprot id: D8JW13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

582899:HDEN RS09365
gene id: 582899:HDEN_RS09365
uniprot id: D8JZA3
names: Similarity
messages: Belongs to the citrate synthase family.

582899:HDEN RS06175
gene id: 582899:HDEN_RS06175
uniprot id: D8JWF2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

582899:HDEN RS02970
gene id: 582899:HDEN_RS02970
uniprot id: D8JSU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.

582899:HDEN RS15985
gene id: 582899:HDEN_RS15985
uniprot id: D8JWR7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

582899:HDEN RS06430
gene id: 582899:HDEN_RS06430
uniprot id: D8JWK3
names: Subcellular Location Annotation
messages: Membrane