577650:DESPR RS05415
gene id: 577650:DESPR_RS05415
uniprot id: A0A7U3YKX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS01555
gene id: 577650:DESPR_RS01555
uniprot id: A0A7U3YJE8
names: Similarity
messages: Belongs to the UPF0235 family.

577650:DESPR RS07530
gene id: 577650:DESPR_RS07530
uniprot id: A0A7U4DP11
names: Similarity
messages: Belongs to the peptidase S66 family.

577650:DESPR RS15155
gene id: 577650:DESPR_RS15155
uniprot id: A0A7U3YPH5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

577650:DESPR RS08880
gene id: 577650:DESPR_RS08880
uniprot id: A0A7U3YM64
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

577650:DESPR RS05815
gene id: 577650:DESPR_RS05815
uniprot id: A0A7U3YL20
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

577650:DESPR RS06540
gene id: 577650:DESPR_RS06540
uniprot id: A0A7U3YLA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

577650:DESPR RS02125
gene id: 577650:DESPR_RS02125
uniprot id: A0A7U4DN12
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

577650:DESPR RS08415
gene id: 577650:DESPR_RS08415
uniprot id: A0A7U3YM03
names: Similarity
messages: Belongs to the transposase 7 family.

577650:DESPR RS05495
gene id: 577650:DESPR_RS05495
uniprot id: A0A7U3YKX1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

577650:DESPR RS06670
gene id: 577650:DESPR_RS06670
uniprot id: A0A7U3YJ18
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

577650:DESPR RS13120
gene id: 577650:DESPR_RS13120
uniprot id: A0A7U3YNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

577650:DESPR RS11275
gene id: 577650:DESPR_RS11275
uniprot id: A0A7U3YN31
names: Similarity
messages: Belongs to the UPF0047 family.

577650:DESPR RS01895
gene id: 577650:DESPR_RS01895
uniprot id: A0A7U3YJK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

577650:DESPR RS12810
gene id: 577650:DESPR_RS12810
uniprot id: A0A7U3YNM9
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS09600
gene id: 577650:DESPR_RS09600
uniprot id: A0A7U4DPF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

577650:DESPR RS00035
gene id: 577650:DESPR_RS00035
uniprot id: A0A7U4DMH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS03160
gene id: 577650:DESPR_RS03160
uniprot id: A0A7U4DN94
names: Similarity
messages: Belongs to the GSP E family.

577650:DESPR RS14605
gene id: 577650:DESPR_RS14605
uniprot id: A0A7U3YPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

577650:DESPR RS12430
gene id: 577650:DESPR_RS12430
uniprot id: A0A7U3YNG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

577650:DESPR RS03970
gene id: 577650:DESPR_RS03970
uniprot id: A0A7U4DNJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

577650:DESPR RS16050
gene id: 577650:DESPR_RS16050
uniprot id: A0A7U3YQ24
names: Similarity
messages: Belongs to the DEAD box helicase family.

577650:DESPR RS04490
gene id: 577650:DESPR_RS04490
uniprot id: A0A7U4DNM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

577650:DESPR RS11155
gene id: 577650:DESPR_RS11155
uniprot id: A0A7U3YN12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

577650:DESPR RS12455
gene id: 577650:DESPR_RS12455
uniprot id: A0A7U4DQ06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

577650:DESPR RS17020
gene id: 577650:DESPR_RS17020
uniprot id: A0A7U3YK40
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS12405
gene id: 577650:DESPR_RS12405
uniprot id: A0A7U3YNH0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS14970
gene id: 577650:DESPR_RS14970
uniprot id: A0A7U4DQI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

577650:DESPR RS11370
gene id: 577650:DESPR_RS11370
uniprot id: A0A7U4DPQ9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

577650:DESPR RS11680
gene id: 577650:DESPR_RS11680
uniprot id: A0A7U3YJ18
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

577650:DESPR RS00450
gene id: 577650:DESPR_RS00450
uniprot id: A0A7U4DMS8
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

577650:DESPR RS16215
gene id: 577650:DESPR_RS16215
uniprot id: A0A7U4DQP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

577650:DESPR RS00350
gene id: 577650:DESPR_RS00350
uniprot id: A0A7U3YIY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS13665
gene id: 577650:DESPR_RS13665
uniprot id: A0A7U3YNY5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

577650:DESPR RS00435
gene id: 577650:DESPR_RS00435
uniprot id: A0A7U3YIZ2
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS06635
gene id: 577650:DESPR_RS06635
uniprot id: A0A7U3YLD3
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS06220
gene id: 577650:DESPR_RS06220
uniprot id: A0A7U4DNT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS09710
gene id: 577650:DESPR_RS09710
uniprot id: A0A7U3YMR8
names: Similarity
messages: Belongs to the peptidase S58 family.

577650:DESPR RS13305
gene id: 577650:DESPR_RS13305
uniprot id: A0A7U3YP27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

577650:DESPR RS10910
gene id: 577650:DESPR_RS10910
uniprot id: A0A7U4DPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

577650:DESPR RS03940
gene id: 577650:DESPR_RS03940
uniprot id: A0A7U4DNF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

577650:DESPR RS13735
gene id: 577650:DESPR_RS13735
uniprot id: A0A7U4DQ60
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

577650:DESPR RS13900
gene id: 577650:DESPR_RS13900
uniprot id: A0A7U3YP07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

577650:DESPR RS16815
gene id: 577650:DESPR_RS16815
uniprot id: A0A7U4DQW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

577650:DESPR RS12535
gene id: 577650:DESPR_RS12535
uniprot id: A0A7U3YNI4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

577650:DESPR RS04340
gene id: 577650:DESPR_RS04340
uniprot id: A0A7U3YKK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS03520
gene id: 577650:DESPR_RS03520
uniprot id: A0A7U3YK63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS08845
gene id: 577650:DESPR_RS08845
uniprot id: A0A7U3YM42
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS00640
gene id: 577650:DESPR_RS00640
uniprot id: A0A7U3YJ21
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS08355
gene id: 577650:DESPR_RS08355
uniprot id: A0A7U4DP97
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

577650:DESPR RS15750
gene id: 577650:DESPR_RS15750
uniprot id: A0A7U4DQM8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

577650:DESPR RS07605
gene id: 577650:DESPR_RS07605
uniprot id: A0A7U3YLP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

577650:DESPR RS13535
gene id: 577650:DESPR_RS13535
uniprot id: A0A7U3YP55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

577650:DESPR RS02605
gene id: 577650:DESPR_RS02605
uniprot id: A0A7U3YJU4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS07940
gene id: 577650:DESPR_RS07940
uniprot id: A0A7U3YLU9
names: Similarity
messages: Belongs to the peptidase C1 family.

577650:DESPR RS16065
gene id: 577650:DESPR_RS16065
uniprot id: A0A7U4DQL9
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS09625
gene id: 577650:DESPR_RS09625
uniprot id: A0A7U3YMG3
names: Subcellular Location Annotation
messages: Cytoplasm

577650:DESPR RS03955
gene id: 577650:DESPR_RS03955
uniprot id: A0A7U3YKK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

577650:DESPR RS05270
gene id: 577650:DESPR_RS05270
uniprot id: A0A7U3YKU4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

577650:DESPR RS13215
gene id: 577650:DESPR_RS13215
uniprot id: A0A7U3YNR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

577650:DESPR RS06310
gene id: 577650:DESPR_RS06310
uniprot id: A0A7U3YL82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

577650:DESPR RS07030
gene id: 577650:DESPR_RS07030
uniprot id: A0A7U4DP10
names: Subcellular Location Annotation
messages: Cell inner membrane

577650:DESPR RS13660
gene id: 577650:DESPR_RS13660
uniprot id: A0A7U4DQ55
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS07435
gene id: 577650:DESPR_RS07435
uniprot id: A0A7U3YLY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

577650:DESPR RS14010
gene id: 577650:DESPR_RS14010
uniprot id: A0A7U4DQB4
names: Similarity
messages: Belongs to the RemA family.

577650:DESPR RS07965
gene id: 577650:DESPR_RS07965
uniprot id: A0A7U3YLU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

577650:DESPR RS06305
gene id: 577650:DESPR_RS06305
uniprot id: A0A7U3YL76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

577650:DESPR RS01370
gene id: 577650:DESPR_RS01370
uniprot id: A0A7U4DMY9
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS04720
gene id: 577650:DESPR_RS04720
uniprot id: A0A7U4DNP0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

577650:DESPR RS06105
gene id: 577650:DESPR_RS06105
uniprot id: A0A7U4DNU5
names: Subunit
messages: Heterodimer of a large and a small subunit.

577650:DESPR RS04420
gene id: 577650:DESPR_RS04420
uniprot id: A0A7U4DNH0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS13580
gene id: 577650:DESPR_RS13580
uniprot id: A0A7U4DQ50
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

577650:DESPR RS02650
gene id: 577650:DESPR_RS02650
uniprot id: A0A7U4DN61
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

577650:DESPR RS09075
gene id: 577650:DESPR_RS09075
uniprot id: A0A7U3YM81
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

577650:DESPR RS09550
gene id: 577650:DESPR_RS09550
uniprot id: A0A7U3YMF1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

577650:DESPR RS17010
gene id: 577650:DESPR_RS17010
uniprot id: A0A7U3YK31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS07345
gene id: 577650:DESPR_RS07345
uniprot id: A0A7U3YLL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS15825
gene id: 577650:DESPR_RS15825
uniprot id: A0A7U4DQN1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

577650:DESPR RS00040
gene id: 577650:DESPR_RS00040
uniprot id: A0A7U3YIS5
names: Similarity
messages: Belongs to the HdrA family.

577650:DESPR RS09315
gene id: 577650:DESPR_RS09315
uniprot id: A0A7U3YMA1
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS12475
gene id: 577650:DESPR_RS12475
uniprot id: A0A7U3YNH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

577650:DESPR RS15800
gene id: 577650:DESPR_RS15800
uniprot id: A0A7U3YPR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

577650:DESPR RS03630
gene id: 577650:DESPR_RS03630
uniprot id: A0A7U4DNC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

577650:DESPR RS04050
gene id: 577650:DESPR_RS04050
uniprot id: A0A7U3YKE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

577650:DESPR RS10285
gene id: 577650:DESPR_RS10285
uniprot id: A0A7U3YMN9
names: Similarity
messages: Belongs to the P(II) protein family.

577650:DESPR RS08590
gene id: 577650:DESPR_RS08590
uniprot id: A0A7U3YMD7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

577650:DESPR RS11530
gene id: 577650:DESPR_RS11530
uniprot id: A0A7U3YN53
names: Similarity
messages: Belongs to the leucine-binding protein family.

577650:DESPR RS11605
gene id: 577650:DESPR_RS11605
uniprot id: A0A7U3YN64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

577650:DESPR RS03565
gene id: 577650:DESPR_RS03565
uniprot id: A0A7U3YK81
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

577650:DESPR RS15580
gene id: 577650:DESPR_RS15580
uniprot id: A0A7U4DQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS17395
gene id: 577650:DESPR_RS17395
uniprot id: A0A7U4DPZ3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

577650:DESPR RS16455
gene id: 577650:DESPR_RS16455
uniprot id: A0A7U4DQN9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS05695
gene id: 577650:DESPR_RS05695
uniprot id: A0A7U3YL79
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS16560
gene id: 577650:DESPR_RS16560
uniprot id: A0A7U3YPZ3
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

577650:DESPR RS06315
gene id: 577650:DESPR_RS06315
uniprot id: A0A7U3YL94
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

577650:DESPR RS04855
gene id: 577650:DESPR_RS04855
uniprot id: A0A7U4DNM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

577650:DESPR RS11310
gene id: 577650:DESPR_RS11310
uniprot id: A0A7U3YN32
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

577650:DESPR RS08730
gene id: 577650:DESPR_RS08730
uniprot id: A0A7U3YM45
names: Similarity
messages: Belongs to the HypE family.

577650:DESPR RS01825
gene id: 577650:DESPR_RS01825
uniprot id: A0A7U3YJI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

577650:DESPR RS01190
gene id: 577650:DESPR_RS01190
uniprot id: A0A7U3YJE7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

577650:DESPR RS08715
gene id: 577650:DESPR_RS08715
uniprot id: A0A7U4DP93
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

577650:DESPR RS15450
gene id: 577650:DESPR_RS15450
uniprot id: A0A7U4DQP2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS02520
gene id: 577650:DESPR_RS02520
uniprot id: A0A7U3YJT0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

577650:DESPR RS12045
gene id: 577650:DESPR_RS12045
uniprot id: A0A7U3YNC5
names: Subcellular Location Annotation
messages: Cytoplasm

577650:DESPR RS11420
gene id: 577650:DESPR_RS11420
uniprot id: A0A7U3YN55
names: Similarity
messages: Belongs to the Nth/MutY family.

577650:DESPR RS09835
gene id: 577650:DESPR_RS09835
uniprot id: A0A7U3YMI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

577650:DESPR RS02270
gene id: 577650:DESPR_RS02270
uniprot id: A0A7U4DN75
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

577650:DESPR RS16595
gene id: 577650:DESPR_RS16595
uniprot id: A0A7U3YQ83
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

577650:DESPR RS03395
gene id: 577650:DESPR_RS03395
uniprot id: A0A7U4DNB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS14830
gene id: 577650:DESPR_RS14830
uniprot id: A0A7U4DQH3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

577650:DESPR RS01435
gene id: 577650:DESPR_RS01435
uniprot id: A0A7U4DMY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

577650:DESPR RS14450
gene id: 577650:DESPR_RS14450
uniprot id: A0A7U3YP93
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

577650:DESPR RS13180
gene id: 577650:DESPR_RS13180
uniprot id: A0A7U4DQ31
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

577650:DESPR RS14430
gene id: 577650:DESPR_RS14430
uniprot id: A0A7U3YP86
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

577650:DESPR RS05275
gene id: 577650:DESPR_RS05275
uniprot id: A0A7U4DNL9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

577650:DESPR RS10365
gene id: 577650:DESPR_RS10365
uniprot id: A0A7U3YMQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

577650:DESPR RS17440
gene id: 577650:DESPR_RS17440
uniprot id: A0A7U3YNI8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS12485
gene id: 577650:DESPR_RS12485
uniprot id: A0A7U3YNH8
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

577650:DESPR RS02215
gene id: 577650:DESPR_RS02215
uniprot id: A0A7U4DN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

577650:DESPR RS05570
gene id: 577650:DESPR_RS05570
uniprot id: A0A7U3YKZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

577650:DESPR RS10175
gene id: 577650:DESPR_RS10175
uniprot id: A0A7U4DPP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

577650:DESPR RS01405
gene id: 577650:DESPR_RS01405
uniprot id: A0A7U3YJC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

577650:DESPR RS05650
gene id: 577650:DESPR_RS05650
uniprot id: A0A7U3YL00
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

577650:DESPR RS02875
gene id: 577650:DESPR_RS02875
uniprot id: A0A7U3YK06
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

577650:DESPR RS10970
gene id: 577650:DESPR_RS10970
uniprot id: A0A7U3YMX5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

577650:DESPR RS03690
gene id: 577650:DESPR_RS03690
uniprot id: A0A7U4DND8
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

577650:DESPR RS04940
gene id: 577650:DESPR_RS04940
uniprot id: A0A7U4DNQ4
names: Similarity
messages: Belongs to the universal stress protein A family.

577650:DESPR RS00100
gene id: 577650:DESPR_RS00100
uniprot id: A0A7U3YIU9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

577650:DESPR RS08410
gene id: 577650:DESPR_RS08410
uniprot id: A0A7U3YM01
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

577650:DESPR RS07085
gene id: 577650:DESPR_RS07085
uniprot id: A0A7U3YLJ0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS04690
gene id: 577650:DESPR_RS04690
uniprot id: A0A7U4DNK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

577650:DESPR RS07970
gene id: 577650:DESPR_RS07970
uniprot id: A0A7U3YLT4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

577650:DESPR RS17210
gene id: 577650:DESPR_RS17210
uniprot id: A0A7U3YLP4
names: Similarity
messages: Belongs to the hemerythrin family.

577650:DESPR RS12880
gene id: 577650:DESPR_RS12880
uniprot id: A0A7U4DQ05
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

577650:DESPR RS13975
gene id: 577650:DESPR_RS13975
uniprot id: A0A7U3YP17
names: Similarity
messages: Belongs to the ros/MucR family.

577650:DESPR RS16525
gene id: 577650:DESPR_RS16525
uniprot id: A0A7U3YPZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

577650:DESPR RS04805
gene id: 577650:DESPR_RS04805
uniprot id: A0A7U3YKM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

577650:DESPR RS06605
gene id: 577650:DESPR_RS06605
uniprot id: A0A7U3YLB9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

577650:DESPR RS14670
gene id: 577650:DESPR_RS14670
uniprot id: A0A7U3YPK1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

577650:DESPR RS15150
gene id: 577650:DESPR_RS15150
uniprot id: A0A7U3YPH8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

577650:DESPR RS04015
gene id: 577650:DESPR_RS04015
uniprot id: A0A7U3YKC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

577650:DESPR RS11255
gene id: 577650:DESPR_RS11255
uniprot id: A0A7U3YN38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

577650:DESPR RS12110
gene id: 577650:DESPR_RS12110
uniprot id: A0A7U3YNC6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

577650:DESPR RS11135
gene id: 577650:DESPR_RS11135
uniprot id: A0A7U4DPQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

577650:DESPR RS14005
gene id: 577650:DESPR_RS14005
uniprot id: A0A7U3YPB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

577650:DESPR RS02085
gene id: 577650:DESPR_RS02085
uniprot id: A0A7U3YJW8
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS04000
gene id: 577650:DESPR_RS04000
uniprot id: A0A7U3YKC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

577650:DESPR RS10950
gene id: 577650:DESPR_RS10950
uniprot id: A0A7U4DPR2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

577650:DESPR RS08960
gene id: 577650:DESPR_RS08960
uniprot id: A0A7U3YM70
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

577650:DESPR RS03465
gene id: 577650:DESPR_RS03465
uniprot id: A0A7U3YK60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

577650:DESPR RS11120
gene id: 577650:DESPR_RS11120
uniprot id: A0A7U3YMZ6
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

577650:DESPR RS04495
gene id: 577650:DESPR_RS04495
uniprot id: A0A7U3YKJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS04410
gene id: 577650:DESPR_RS04410
uniprot id: A0A7U4DNJ0
names: Similarity
messages: Belongs to the threonine synthase family.

577650:DESPR RS03405
gene id: 577650:DESPR_RS03405
uniprot id: A0A7U4DNC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS13915
gene id: 577650:DESPR_RS13915
uniprot id: A0A7U3YP08
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

577650:DESPR RS08250
gene id: 577650:DESPR_RS08250
uniprot id: A0A7U3YLY3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

577650:DESPR RS04285
gene id: 577650:DESPR_RS04285
uniprot id: A0A7U3YKG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS08675
gene id: 577650:DESPR_RS08675
uniprot id: A0A7U3YME6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

577650:DESPR RS04865
gene id: 577650:DESPR_RS04865
uniprot id: A0A7U4DNJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

577650:DESPR RS10305
gene id: 577650:DESPR_RS10305
uniprot id: A0A7U4DPM6
names: Subcellular Location Annotation
messages: Periplasm

577650:DESPR RS15235
gene id: 577650:DESPR_RS15235
uniprot id: A0A7U3YPK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

577650:DESPR RS07110
gene id: 577650:DESPR_RS07110
uniprot id: A0A7U4DP17
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

577650:DESPR RS14775
gene id: 577650:DESPR_RS14775
uniprot id: A0A7U3YPD1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

577650:DESPR RS04890
gene id: 577650:DESPR_RS04890
uniprot id: A0A7U4DNI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS16790
gene id: 577650:DESPR_RS16790
uniprot id: A0A7U3YQ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

577650:DESPR RS09850
gene id: 577650:DESPR_RS09850
uniprot id: A0A7U3YMJ5
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

577650:DESPR RS11985
gene id: 577650:DESPR_RS11985
uniprot id: A0A7U4DPX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

577650:DESPR RS10750
gene id: 577650:DESPR_RS10750
uniprot id: A0A7U3YMV8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

577650:DESPR RS01805
gene id: 577650:DESPR_RS01805
uniprot id: A0A7U3YJJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

577650:DESPR RS08690
gene id: 577650:DESPR_RS08690
uniprot id: A0A7U4DP85
names: Similarity
messages: Belongs to the HdrA family.

577650:DESPR RS07955
gene id: 577650:DESPR_RS07955
uniprot id: A0A7U3YLT7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

577650:DESPR RS16275
gene id: 577650:DESPR_RS16275
uniprot id: A0A7U3YQ79
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

577650:DESPR RS13060
gene id: 577650:DESPR_RS13060
uniprot id: A0A7U3YNR4
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.

577650:DESPR RS08245
gene id: 577650:DESPR_RS08245
uniprot id: A0A7U3YLW7
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS06980
gene id: 577650:DESPR_RS06980
uniprot id: A0A7U4DNY3
names: Similarity
messages: Belongs to the TrpF family.

577650:DESPR RS10575
gene id: 577650:DESPR_RS10575
uniprot id: A0A7U3YMS9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

577650:DESPR RS07375
gene id: 577650:DESPR_RS07375
uniprot id: A0A7U4DP02
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS04870
gene id: 577650:DESPR_RS04870
uniprot id: A0A7U4DNP7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

577650:DESPR RS13395
gene id: 577650:DESPR_RS13395
uniprot id: A0A7U4DQ44
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

577650:DESPR RS00235
gene id: 577650:DESPR_RS00235
uniprot id: A0A7U3YJ07
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

577650:DESPR RS16160
gene id: 577650:DESPR_RS16160
uniprot id: A0A7U3YPW6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

577650:DESPR RS10215
gene id: 577650:DESPR_RS10215
uniprot id: A0A7U3YMN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

577650:DESPR RS16735
gene id: 577650:DESPR_RS16735
uniprot id: A0A7U3YQD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

577650:DESPR RS12400
gene id: 577650:DESPR_RS12400
uniprot id: A0A7U3YNG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

577650:DESPR RS12030
gene id: 577650:DESPR_RS12030
uniprot id: A0A7U3YNC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

577650:DESPR RS13300
gene id: 577650:DESPR_RS13300
uniprot id: A0A7U4DQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

577650:DESPR RS14745
gene id: 577650:DESPR_RS14745
uniprot id: A0A7U4DQF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

577650:DESPR RS08755
gene id: 577650:DESPR_RS08755
uniprot id: A0A7U4DPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

577650:DESPR RS18910
gene id: 577650:DESPR_RS18910
uniprot id: A0A7U3YKT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

577650:DESPR RS01560
gene id: 577650:DESPR_RS01560
uniprot id: A0A7U3YJF0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS08495
gene id: 577650:DESPR_RS08495
uniprot id: A0A7U3YM20
names: Similarity
messages: Belongs to the hemerythrin family.

577650:DESPR RS06530
gene id: 577650:DESPR_RS06530
uniprot id: A0A7U3YLB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

577650:DESPR RS16345
gene id: 577650:DESPR_RS16345
uniprot id: A0A7U3YPW8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

577650:DESPR RS03765
gene id: 577650:DESPR_RS03765
uniprot id: A0A7U3YK95
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS03430
gene id: 577650:DESPR_RS03430
uniprot id: A0A7U3YK55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

577650:DESPR RS13595
gene id: 577650:DESPR_RS13595
uniprot id: A0A7U3YNX0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

577650:DESPR RS11940
gene id: 577650:DESPR_RS11940
uniprot id: A0A7U3YNA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

577650:DESPR RS01660
gene id: 577650:DESPR_RS01660
uniprot id: A0A7U3YJR0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

577650:DESPR RS09690
gene id: 577650:DESPR_RS09690
uniprot id: A0A7U3YMG2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

577650:DESPR RS08775
gene id: 577650:DESPR_RS08775
uniprot id: A0A7U3YM36
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

577650:DESPR RS16075
gene id: 577650:DESPR_RS16075
uniprot id: A0A7U3YPT7
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS06565
gene id: 577650:DESPR_RS06565
uniprot id: A0A7U4DNY2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS10490
gene id: 577650:DESPR_RS10490
uniprot id: A0A7U4DPK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS13155
gene id: 577650:DESPR_RS13155
uniprot id: A0A7U3YNR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

577650:DESPR RS11130
gene id: 577650:DESPR_RS11130
uniprot id: A0A7U3YN05
names: Similarity
messages: Belongs to the MotB family.

577650:DESPR RS03260
gene id: 577650:DESPR_RS03260
uniprot id: A0A7U4DNE9
names: Similarity
messages: Belongs to the GSP E family.

577650:DESPR RS12990
gene id: 577650:DESPR_RS12990
uniprot id: A0A7U3YNY1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

577650:DESPR RS16290
gene id: 577650:DESPR_RS16290
uniprot id: A0A7U4DQQ1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

577650:DESPR RS15085
gene id: 577650:DESPR_RS15085
uniprot id: A0A7U3YPI3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

577650:DESPR RS07785
gene id: 577650:DESPR_RS07785
uniprot id: A0A7U3YLT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

577650:DESPR RS12570
gene id: 577650:DESPR_RS12570
uniprot id: A0A7U4DPY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

577650:DESPR RS10005
gene id: 577650:DESPR_RS10005
uniprot id: A0A7U3YMW1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

577650:DESPR RS00110
gene id: 577650:DESPR_RS00110
uniprot id: A0A7U4DMI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

577650:DESPR RS08315
gene id: 577650:DESPR_RS08315
uniprot id: A0A7U3YLW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

577650:DESPR RS13245
gene id: 577650:DESPR_RS13245
uniprot id: A0A7U4DQ36
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

577650:DESPR RS03965
gene id: 577650:DESPR_RS03965
uniprot id: A0A7U4DNE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

577650:DESPR RS13605
gene id: 577650:DESPR_RS13605
uniprot id: A0A7U3YNX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

577650:DESPR RS05360
gene id: 577650:DESPR_RS05360
uniprot id: A0A7U3YKV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

577650:DESPR RS11840
gene id: 577650:DESPR_RS11840
uniprot id: A0A7U3YNA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

577650:DESPR RS16220
gene id: 577650:DESPR_RS16220
uniprot id: A0A7U3YPV9
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS04735
gene id: 577650:DESPR_RS04735
uniprot id: A0A7U3YKN0
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS13290
gene id: 577650:DESPR_RS13290
uniprot id: A0A7U3YNS9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

577650:DESPR RS06940
gene id: 577650:DESPR_RS06940
uniprot id: A0A7U3YLR8
names: Similarity
messages: Belongs to the AOR/FOR family.

577650:DESPR RS14065
gene id: 577650:DESPR_RS14065
uniprot id: A0A7U3YP29
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

577650:DESPR RS13210
gene id: 577650:DESPR_RS13210
uniprot id: A0A7U3YNT0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS11340
gene id: 577650:DESPR_RS11340
uniprot id: A0A7U4DPR0
names: Similarity
messages: Belongs to the peptidase S16 family.

577650:DESPR RS02865
gene id: 577650:DESPR_RS02865
uniprot id: A0A7U3YK62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

577650:DESPR RS05585
gene id: 577650:DESPR_RS05585
uniprot id: A0A7U3YKY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

577650:DESPR RS02700
gene id: 577650:DESPR_RS02700
uniprot id: A0A7U3YJW1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

577650:DESPR RS05370
gene id: 577650:DESPR_RS05370
uniprot id: A0A7U3YKX8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

577650:DESPR RS16705
gene id: 577650:DESPR_RS16705
uniprot id: A0A7U3YQ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

577650:DESPR RS13065
gene id: 577650:DESPR_RS13065
uniprot id: A0A7U3YNP2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

577650:DESPR RS09905
gene id: 577650:DESPR_RS09905
uniprot id: A0A7U3YMI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

577650:DESPR RS09110
gene id: 577650:DESPR_RS09110
uniprot id: A0A7U3YM89
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

577650:DESPR RS10650
gene id: 577650:DESPR_RS10650
uniprot id: A0A7U4DPL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

577650:DESPR RS10265
gene id: 577650:DESPR_RS10265
uniprot id: A0A7U3YMP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS11065
gene id: 577650:DESPR_RS11065
uniprot id: A0A7U3YMZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

577650:DESPR RS08310
gene id: 577650:DESPR_RS08310
uniprot id: A0A7U4DPB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS10840
gene id: 577650:DESPR_RS10840
uniprot id: A0A7U3YMX3
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS14415
gene id: 577650:DESPR_RS14415
uniprot id: A0A7U3YP82
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

577650:DESPR RS07860
gene id: 577650:DESPR_RS07860
uniprot id: A0A7U3YLS0
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

577650:DESPR RS11405
gene id: 577650:DESPR_RS11405
uniprot id: A0A7U4DPU5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

577650:DESPR RS13095
gene id: 577650:DESPR_RS13095
uniprot id: A0A7U4DQ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

577650:DESPR RS11930
gene id: 577650:DESPR_RS11930
uniprot id: A0A7U3YNA4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

577650:DESPR RS14805
gene id: 577650:DESPR_RS14805
uniprot id: A0A7U3YPD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

577650:DESPR RS11435
gene id: 577650:DESPR_RS11435
uniprot id: A0A7U3YN36
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

577650:DESPR RS00310
gene id: 577650:DESPR_RS00310
uniprot id: A0A7U3YJ18
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

577650:DESPR RS07705
gene id: 577650:DESPR_RS07705
uniprot id: A0A7U3YLQ3
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS07050
gene id: 577650:DESPR_RS07050
uniprot id: A0A7U3YLG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

577650:DESPR RS17235
gene id: 577650:DESPR_RS17235
uniprot id: A0A7U4DPA4
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS12960
gene id: 577650:DESPR_RS12960
uniprot id: A0A7U3YNQ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

577650:DESPR RS10795
gene id: 577650:DESPR_RS10795
uniprot id: A0A7U4DPM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

577650:DESPR RS16700
gene id: 577650:DESPR_RS16700
uniprot id: A0A7U3YQ03
names: Similarity
messages: Belongs to the peptidase A31 family.

577650:DESPR RS14280
gene id: 577650:DESPR_RS14280
uniprot id: A0A7U3YP66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS09285
gene id: 577650:DESPR_RS09285
uniprot id: A0A7U4DPC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS05600
gene id: 577650:DESPR_RS05600
uniprot id: A0A7U3YL07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cholesterol-dependent cytolysin family.
messages: Membrane
messages: Secreted

577650:DESPR RS09320
gene id: 577650:DESPR_RS09320
uniprot id: A0A7U3YMB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

577650:DESPR RS06120
gene id: 577650:DESPR_RS06120
uniprot id: A0A7U4DNS2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

577650:DESPR RS02255
gene id: 577650:DESPR_RS02255
uniprot id: A0A7U4DN45
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

577650:DESPR RS09440
gene id: 577650:DESPR_RS09440
uniprot id: A0A7U4DPJ0
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS01240
gene id: 577650:DESPR_RS01240
uniprot id: A0A7U3YJB2
names: Similarity
messages: Belongs to the HsdR family.

577650:DESPR RS03135
gene id: 577650:DESPR_RS03135
uniprot id: A0A7U3YK08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

577650:DESPR RS06070
gene id: 577650:DESPR_RS06070
uniprot id: A0A7U3YL51
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

577650:DESPR RS08940
gene id: 577650:DESPR_RS08940
uniprot id: A0A7U3YM49
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

577650:DESPR RS11835
gene id: 577650:DESPR_RS11835
uniprot id: A0A7U4DPW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

577650:DESPR RS13630
gene id: 577650:DESPR_RS13630
uniprot id: A0A7U3YNX3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

577650:DESPR RS15165
gene id: 577650:DESPR_RS15165
uniprot id: A0A7U4DQE9
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

577650:DESPR RS07465
gene id: 577650:DESPR_RS07465
uniprot id: A0A7U3YLM4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

577650:DESPR RS16300
gene id: 577650:DESPR_RS16300
uniprot id: A0A7U4DQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

577650:DESPR RS01410
gene id: 577650:DESPR_RS01410
uniprot id: A0A7U3YJE3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS06990
gene id: 577650:DESPR_RS06990
uniprot id: A0A7U3YLG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS08215
gene id: 577650:DESPR_RS08215
uniprot id: A0A7U3YLY2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

577650:DESPR RS07900
gene id: 577650:DESPR_RS07900
uniprot id: A0A7U4DP65
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

577650:DESPR RS13220
gene id: 577650:DESPR_RS13220
uniprot id: A0A7U3YNS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

577650:DESPR RS01925
gene id: 577650:DESPR_RS01925
uniprot id: A0A7U3YJK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

577650:DESPR RS15645
gene id: 577650:DESPR_RS15645
uniprot id: A0A7U3YPN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

577650:DESPR RS11955
gene id: 577650:DESPR_RS11955
uniprot id: A0A7U3YNB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

577650:DESPR RS16320
gene id: 577650:DESPR_RS16320
uniprot id: A0A7U3YPY3
names: Similarity
messages: Belongs to the LarC family.

577650:DESPR RS13205
gene id: 577650:DESPR_RS13205
uniprot id: A0A7U4DQ23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS05105
gene id: 577650:DESPR_RS05105
uniprot id: A0A7U4DNQ9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

577650:DESPR RS04605
gene id: 577650:DESPR_RS04605
uniprot id: A0A7U3YKL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

577650:DESPR RS01545
gene id: 577650:DESPR_RS01545
uniprot id: A0A7U3YJE9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS10945
gene id: 577650:DESPR_RS10945
uniprot id: A0A7U3YN75
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

577650:DESPR RS03670
gene id: 577650:DESPR_RS03670
uniprot id: A0A7U3YK89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

577650:DESPR RS11260
gene id: 577650:DESPR_RS11260
uniprot id: A0A7U4DPQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

577650:DESPR RS11265
gene id: 577650:DESPR_RS11265
uniprot id: A0A7U4DPW9
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

577650:DESPR RS13360
gene id: 577650:DESPR_RS13360
uniprot id: A0A7U3YNT5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

577650:DESPR RS00420
gene id: 577650:DESPR_RS00420
uniprot id: A0A7U3YIY9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

577650:DESPR RS15530
gene id: 577650:DESPR_RS15530
uniprot id: A0A7U3YPM5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

577650:DESPR RS01625
gene id: 577650:DESPR_RS01625
uniprot id: A0A7U4DMX3
names: Similarity
messages: Belongs to the asparagine synthetase family.

577650:DESPR RS12015
gene id: 577650:DESPR_RS12015
uniprot id: A0A7U3YNB5
names: Subunit
messages: Heterodimer of a large and a small subunit.

577650:DESPR RS01355
gene id: 577650:DESPR_RS01355
uniprot id: A0A7U3YJM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS05180
gene id: 577650:DESPR_RS05180
uniprot id: A0A7U4DNR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

577650:DESPR RS04610
gene id: 577650:DESPR_RS04610
uniprot id: A0A7U3YKL9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

577650:DESPR RS10105
gene id: 577650:DESPR_RS10105
uniprot id: A0A7U3YMM6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

577650:DESPR RS13310
gene id: 577650:DESPR_RS13310
uniprot id: A0A7U4DQ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

577650:DESPR RS01495
gene id: 577650:DESPR_RS01495
uniprot id: A0A7U3YJE2
names: Similarity
messages: Belongs to the HisA/HisF family.

577650:DESPR RS06550
gene id: 577650:DESPR_RS06550
uniprot id: A0A7U3YLB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS13275
gene id: 577650:DESPR_RS13275
uniprot id: A0A7U3YNU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

577650:DESPR RS16130
gene id: 577650:DESPR_RS16130
uniprot id: A0A7U4DQP3
names: Similarity
messages: Belongs to the bacterial secretin family.

577650:DESPR RS04595
gene id: 577650:DESPR_RS04595
uniprot id: A0A7U3YKL1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

577650:DESPR RS16785
gene id: 577650:DESPR_RS16785
uniprot id: A0A7U4DQQ5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

577650:DESPR RS09510
gene id: 577650:DESPR_RS09510
uniprot id: A0A7U4DPJ5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

577650:DESPR RS10065
gene id: 577650:DESPR_RS10065
uniprot id: A0A7U3YMM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

577650:DESPR RS04330
gene id: 577650:DESPR_RS04330
uniprot id: A0A7U3YKP2
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS03570
gene id: 577650:DESPR_RS03570
uniprot id: A0A7U3YK75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

577650:DESPR RS10315
gene id: 577650:DESPR_RS10315
uniprot id: A0A7U4DPM3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS14940
gene id: 577650:DESPR_RS14940
uniprot id: A0A7U3YPE8
names: Similarity
messages: Belongs to the UPF0045 family.

577650:DESPR RS17445
gene id: 577650:DESPR_RS17445
uniprot id: A0A7U4DQ20
names: Subcellular Location Annotation
messages: Cell inner membrane

577650:DESPR RS08190
gene id: 577650:DESPR_RS08190
uniprot id: A0A7U3YLX7
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

577650:DESPR RS06125
gene id: 577650:DESPR_RS06125
uniprot id: A0A7U4DNW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS10025
gene id: 577650:DESPR_RS10025
uniprot id: A0A7U4DPN1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

577650:DESPR RS14860
gene id: 577650:DESPR_RS14860
uniprot id: A0A7U3YPF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

577650:DESPR RS03980
gene id: 577650:DESPR_RS03980
uniprot id: A0A7U3YKD1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

577650:DESPR RS04500
gene id: 577650:DESPR_RS04500
uniprot id: A0A7U3YKI8
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

577650:DESPR RS14335
gene id: 577650:DESPR_RS14335
uniprot id: A0A7U4DQA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS10580
gene id: 577650:DESPR_RS10580
uniprot id: A0A7U3YMT3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

577650:DESPR RS14735
gene id: 577650:DESPR_RS14735
uniprot id: A0A7U3YPC3
names: Similarity
messages: Belongs to the DprA/Smf family.

577650:DESPR RS12050
gene id: 577650:DESPR_RS12050
uniprot id: A0A7U4DPY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

577650:DESPR RS10915
gene id: 577650:DESPR_RS10915
uniprot id: A0A7U3YMX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

577650:DESPR RS15830
gene id: 577650:DESPR_RS15830
uniprot id: A0A7U3YPR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

577650:DESPR RS04680
gene id: 577650:DESPR_RS04680
uniprot id: A0A7U3YKM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

577650:DESPR RS03390
gene id: 577650:DESPR_RS03390
uniprot id: A0A7U3YK50
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS15335
gene id: 577650:DESPR_RS15335
uniprot id: A0A7U3YPI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

577650:DESPR RS02920
gene id: 577650:DESPR_RS02920
uniprot id: A0A7U3YJY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

577650:DESPR RS02765
gene id: 577650:DESPR_RS02765
uniprot id: A0A7U3YJV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

577650:DESPR RS04415
gene id: 577650:DESPR_RS04415
uniprot id: A0A7U3YKL7
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

577650:DESPR RS12910
gene id: 577650:DESPR_RS12910
uniprot id: A0A7U4DQ38
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

577650:DESPR RS05010
gene id: 577650:DESPR_RS05010
uniprot id: A0A7U3YJ18
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

577650:DESPR RS15650
gene id: 577650:DESPR_RS15650
uniprot id: A0A7U4DQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

577650:DESPR RS11075
gene id: 577650:DESPR_RS11075
uniprot id: A0A7U3YMZ1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

577650:DESPR RS11070
gene id: 577650:DESPR_RS11070
uniprot id: A0A7U3YMZ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

577650:DESPR RS19125
gene id: 577650:DESPR_RS19125
uniprot id: A0A7U3YJP0
names: Similarity
messages: Belongs to the transglycosylase Slt family.

577650:DESPR RS01525
gene id: 577650:DESPR_RS01525
uniprot id: A0A7U4DMZ7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

577650:DESPR RS05775
gene id: 577650:DESPR_RS05775
uniprot id: A0A7U3YL87
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

577650:DESPR RS09120
gene id: 577650:DESPR_RS09120
uniprot id: A0A7U4DPE6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

577650:DESPR RS09300
gene id: 577650:DESPR_RS09300
uniprot id: A0A7U3YMA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS01750
gene id: 577650:DESPR_RS01750
uniprot id: A0A7U3YJH9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

577650:DESPR RS15865
gene id: 577650:DESPR_RS15865
uniprot id: A0A7U3YPR7
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS14650
gene id: 577650:DESPR_RS14650
uniprot id: A0A7U3YPB8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

577650:DESPR RS00380
gene id: 577650:DESPR_RS00380
uniprot id: A0A7U4DMS2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

577650:DESPR RS14855
gene id: 577650:DESPR_RS14855
uniprot id: A0A7U3YPC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

577650:DESPR RS06275
gene id: 577650:DESPR_RS06275
uniprot id: A0A7U4DNX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

577650:DESPR RS03270
gene id: 577650:DESPR_RS03270
uniprot id: A0A7U3YK33
names: Similarity
messages: Belongs to the DtxR/MntR family.

577650:DESPR RS04485
gene id: 577650:DESPR_RS04485
uniprot id: A0A7U4DNH8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS10135
gene id: 577650:DESPR_RS10135
uniprot id: A0A7U3YMM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

577650:DESPR RS02815
gene id: 577650:DESPR_RS02815
uniprot id: A0A7U3YJX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

577650:DESPR RS14235
gene id: 577650:DESPR_RS14235
uniprot id: A0A7U4DQ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

577650:DESPR RS03575
gene id: 577650:DESPR_RS03575
uniprot id: A0A7U3YK77
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

577650:DESPR RS13645
gene id: 577650:DESPR_RS13645
uniprot id: A0A7U3YNX6
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS01440
gene id: 577650:DESPR_RS01440
uniprot id: A0A7U3YJI1
names: Subunit
messages: Heterodimer of a large and a small subunit.

577650:DESPR RS09250
gene id: 577650:DESPR_RS09250
uniprot id: A0A7U3YMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

577650:DESPR RS11580
gene id: 577650:DESPR_RS11580
uniprot id: A0A7U3YN74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

577650:DESPR RS16335
gene id: 577650:DESPR_RS16335
uniprot id: A0A7U3YPX4
names: Similarity
messages: Belongs to the pyruvate kinase family.

577650:DESPR RS02535
gene id: 577650:DESPR_RS02535
uniprot id: A0A7U3YJS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

577650:DESPR RS01780
gene id: 577650:DESPR_RS01780
uniprot id: A0A7U3YJS9
names: Similarity
messages: Belongs to the P(II) protein family.

577650:DESPR RS08870
gene id: 577650:DESPR_RS08870
uniprot id: A0A7U3YM62
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

577650:DESPR RS09295
gene id: 577650:DESPR_RS09295
uniprot id: A0A7U3YMA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

577650:DESPR RS11085
gene id: 577650:DESPR_RS11085
uniprot id: A0A7U3YMZ2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

577650:DESPR RS01175
gene id: 577650:DESPR_RS01175
uniprot id: A0A7U4DMW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS03855
gene id: 577650:DESPR_RS03855
uniprot id: A0A7U3YKA1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

577650:DESPR RS03485
gene id: 577650:DESPR_RS03485
uniprot id: A0A7U3YK98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

577650:DESPR RS03300
gene id: 577650:DESPR_RS03300
uniprot id: A0A7U3YK34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

577650:DESPR RS00290
gene id: 577650:DESPR_RS00290
uniprot id: A0A7U3YIW6
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS13495
gene id: 577650:DESPR_RS13495
uniprot id: A0A7U3YNV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

577650:DESPR RS02585
gene id: 577650:DESPR_RS02585
uniprot id: A0A7U3YJU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

577650:DESPR RS08930
gene id: 577650:DESPR_RS08930
uniprot id: A0A7U3YM69
names: Similarity
messages: Belongs to the SAICAR synthetase family.

577650:DESPR RS16780
gene id: 577650:DESPR_RS16780
uniprot id: A0A7U3YQ31
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

577650:DESPR RS13415
gene id: 577650:DESPR_RS13415
uniprot id: A0A7U3YNU5
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS16510
gene id: 577650:DESPR_RS16510
uniprot id: A0A7U4DQU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

577650:DESPR RS11080
gene id: 577650:DESPR_RS11080
uniprot id: A0A7U3YN01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

577650:DESPR RS09685
gene id: 577650:DESPR_RS09685
uniprot id: A0A7U3YMF8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

577650:DESPR RS11615
gene id: 577650:DESPR_RS11615
uniprot id: A0A7U3YN70
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

577650:DESPR RS04700
gene id: 577650:DESPR_RS04700
uniprot id: A0A7U3YKU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

577650:DESPR RS07265
gene id: 577650:DESPR_RS07265
uniprot id: A0A7U3YLL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

577650:DESPR RS12460
gene id: 577650:DESPR_RS12460
uniprot id: A0A7U3YNH5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

577650:DESPR RS03200
gene id: 577650:DESPR_RS03200
uniprot id: A0A7U3YK24
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

577650:DESPR RS09790
gene id: 577650:DESPR_RS09790
uniprot id: A0A7U4DPI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

577650:DESPR RS03635
gene id: 577650:DESPR_RS03635
uniprot id: A0A7U4DNH3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

577650:DESPR RS08855
gene id: 577650:DESPR_RS08855
uniprot id: A0A7U3YM63
names: Similarity
messages: Belongs to the aspartokinase family.

577650:DESPR RS11465
gene id: 577650:DESPR_RS11465
uniprot id: A0A7U3YN43
names: Similarity
messages: Belongs to the peptidase M18 family.

577650:DESPR RS12700
gene id: 577650:DESPR_RS12700
uniprot id: A0A7U4DPZ6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

577650:DESPR RS09060
gene id: 577650:DESPR_RS09060
uniprot id: A0A7U4DPA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS16205
gene id: 577650:DESPR_RS16205
uniprot id: A0A7U4DQS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

577650:DESPR RS02645
gene id: 577650:DESPR_RS02645
uniprot id: A0A7U3YJY5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

577650:DESPR RS14390
gene id: 577650:DESPR_RS14390
uniprot id: A0A7U4DQG7
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS05565
gene id: 577650:DESPR_RS05565
uniprot id: A0A7U3YKY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

577650:DESPR RS00060
gene id: 577650:DESPR_RS00060
uniprot id: A0A7U3YIT0
names: Subcellular Location Annotation
messages: Periplasm

577650:DESPR RS16620
gene id: 577650:DESPR_RS16620
uniprot id: A0A7U3YQ00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

577650:DESPR RS03595
gene id: 577650:DESPR_RS03595
uniprot id: A0A7U3YK72
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

577650:DESPR RS04320
gene id: 577650:DESPR_RS04320
uniprot id: A0A7U3YKG5
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS02430
gene id: 577650:DESPR_RS02430
uniprot id: A0A7U3YJR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

577650:DESPR RS14585
gene id: 577650:DESPR_RS14585
uniprot id: A0A7U4DQE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

577650:DESPR RS15130
gene id: 577650:DESPR_RS15130
uniprot id: A0A7U4DQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS04175
gene id: 577650:DESPR_RS04175
uniprot id: A0A7U3YKM8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

577650:DESPR RS10275
gene id: 577650:DESPR_RS10275
uniprot id: A0A7U4DPJ8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS03310
gene id: 577650:DESPR_RS03310
uniprot id: A0A7U4DNA5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

577650:DESPR RS09345
gene id: 577650:DESPR_RS09345
uniprot id: A0A7U3YMM5
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS14275
gene id: 577650:DESPR_RS14275
uniprot id: A0A7U3YP53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS09525
gene id: 577650:DESPR_RS09525
uniprot id: A0A7U4DPF1
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

577650:DESPR RS06640
gene id: 577650:DESPR_RS06640
uniprot id: A0A7U3YLA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

577650:DESPR RS11300
gene id: 577650:DESPR_RS11300
uniprot id: A0A7U3YN27
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

577650:DESPR RS03930
gene id: 577650:DESPR_RS03930
uniprot id: A0A7U3YKB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

577650:DESPR RS03925
gene id: 577650:DESPR_RS03925
uniprot id: A0A7U3YKB3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

577650:DESPR RS09865
gene id: 577650:DESPR_RS09865
uniprot id: A0A7U4DPJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

577650:DESPR RS04010
gene id: 577650:DESPR_RS04010
uniprot id: A0A7U3YKC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

577650:DESPR RS15320
gene id: 577650:DESPR_RS15320
uniprot id: A0A7U3YPL7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

577650:DESPR RS16615
gene id: 577650:DESPR_RS16615
uniprot id: A0A7U4DQV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

577650:DESPR RS12555
gene id: 577650:DESPR_RS12555
uniprot id: A0A7U3YNI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS16730
gene id: 577650:DESPR_RS16730
uniprot id: A0A7U3YQ14
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

577650:DESPR RS15250
gene id: 577650:DESPR_RS15250
uniprot id: A0A7U3YPH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS04260
gene id: 577650:DESPR_RS04260
uniprot id: A0A7U4DNH7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS08030
gene id: 577650:DESPR_RS08030
uniprot id: A0A7U3YLU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

577650:DESPR RS13190
gene id: 577650:DESPR_RS13190
uniprot id: A0A7U3YNR9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).

577650:DESPR RS12725
gene id: 577650:DESPR_RS12725
uniprot id: A0A7U4DPZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

577650:DESPR RS14195
gene id: 577650:DESPR_RS14195
uniprot id: A0A7U3YP49
names: Similarity
messages: Belongs to the HSP15 family.

577650:DESPR RS13935
gene id: 577650:DESPR_RS13935
uniprot id: A0A7U4DQA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS01890
gene id: 577650:DESPR_RS01890
uniprot id: A0A7U4DN54
names: Similarity
messages: Belongs to the LOG family.

577650:DESPR RS13955
gene id: 577650:DESPR_RS13955
uniprot id: A0A7U3YP20
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

577650:DESPR RS11570
gene id: 577650:DESPR_RS11570
uniprot id: A0A7U3YNF9
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS01910
gene id: 577650:DESPR_RS01910
uniprot id: A0A7U4DMZ3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

577650:DESPR RS07575
gene id: 577650:DESPR_RS07575
uniprot id: A0A7U3YLN9
names: Similarity
messages: Belongs to the histone deacetylase family.

577650:DESPR RS11100
gene id: 577650:DESPR_RS11100
uniprot id: A0A7U4DPS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS09545
gene id: 577650:DESPR_RS09545
uniprot id: A0A7U3YMF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

577650:DESPR RS10225
gene id: 577650:DESPR_RS10225
uniprot id: A0A7U3YMP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS08720
gene id: 577650:DESPR_RS08720
uniprot id: A0A7U3YM18
names: Similarity
messages: Belongs to the HupF/HypC family.

577650:DESPR RS15615
gene id: 577650:DESPR_RS15615
uniprot id: A0A7U4DQH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

577650:DESPR RS13570
gene id: 577650:DESPR_RS13570
uniprot id: A0A7U3YNW1
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

577650:DESPR RS09615
gene id: 577650:DESPR_RS09615
uniprot id: A0A7U3YMG1
names: Similarity
messages: Belongs to the peptidase S11 family.

577650:DESPR RS05285
gene id: 577650:DESPR_RS05285
uniprot id: A0A7U3YKT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

577650:DESPR RS03935
gene id: 577650:DESPR_RS03935
uniprot id: A0A7U3YKB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

577650:DESPR RS15790
gene id: 577650:DESPR_RS15790
uniprot id: A0A7U3YPQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

577650:DESPR RS15065
gene id: 577650:DESPR_RS15065
uniprot id: A0A7U4DQF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

577650:DESPR RS17195
gene id: 577650:DESPR_RS17195
uniprot id: A0A7U3YLL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

577650:DESPR RS13505
gene id: 577650:DESPR_RS13505
uniprot id: A0A7U3YNW9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

577650:DESPR RS12620
gene id: 577650:DESPR_RS12620
uniprot id: A0A7U4DPZ1
names: Similarity
messages: Belongs to the peptidase C56 family.

577650:DESPR RS08240
gene id: 577650:DESPR_RS08240
uniprot id: A0A7U3YLW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

577650:DESPR RS10145
gene id: 577650:DESPR_RS10145
uniprot id: A0A7U3YMN2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

577650:DESPR RS07885
gene id: 577650:DESPR_RS07885
uniprot id: A0A7U3YLT8
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS05705
gene id: 577650:DESPR_RS05705
uniprot id: A0A7U3YL14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

577650:DESPR RS01350
gene id: 577650:DESPR_RS01350
uniprot id: A0A7U4DMX2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

577650:DESPR RS09840
gene id: 577650:DESPR_RS09840
uniprot id: A0A7U3YMJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

577650:DESPR RS10630
gene id: 577650:DESPR_RS10630
uniprot id: A0A7U4DPT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS02190
gene id: 577650:DESPR_RS02190
uniprot id: A0A7U3YJP1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS14165
gene id: 577650:DESPR_RS14165
uniprot id: A0A7U4DQ93
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS15330
gene id: 577650:DESPR_RS15330
uniprot id: A0A7U3YPI9
names: Similarity
messages: Belongs to the P(II) protein family.

577650:DESPR RS03695
gene id: 577650:DESPR_RS03695
uniprot id: A0A7U3YKC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

577650:DESPR RS02130
gene id: 577650:DESPR_RS02130
uniprot id: A0A7U3YJN0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

577650:DESPR RS15205
gene id: 577650:DESPR_RS15205
uniprot id: A0A7U4DQJ7
names: Similarity
messages: Belongs to the group II decarboxylase family.

577650:DESPR RS07740
gene id: 577650:DESPR_RS07740
uniprot id: A0A7U3YLQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS03290
gene id: 577650:DESPR_RS03290
uniprot id: A0A7U3YK36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

577650:DESPR RS06590
gene id: 577650:DESPR_RS06590
uniprot id: A0A7U4DNV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

577650:DESPR RS14635
gene id: 577650:DESPR_RS14635
uniprot id: A0A7U4DQB7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

577650:DESPR RS10450
gene id: 577650:DESPR_RS10450
uniprot id: A0A7U3YN13
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

577650:DESPR RS10460
gene id: 577650:DESPR_RS10460
uniprot id: A0A7U3YMU0
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS16520
gene id: 577650:DESPR_RS16520
uniprot id: A0A7U4DQR4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

577650:DESPR RS15230
gene id: 577650:DESPR_RS15230
uniprot id: A0A7U3YPI6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

577650:DESPR RS14665
gene id: 577650:DESPR_RS14665
uniprot id: A0A7U4DQF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

577650:DESPR RS05045
gene id: 577650:DESPR_RS05045
uniprot id: A0A7U3YKR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS00200
gene id: 577650:DESPR_RS00200
uniprot id: A0A7U3YIV2
names: Similarity
messages: Belongs to the GSP E family.

577650:DESPR RS07430
gene id: 577650:DESPR_RS07430
uniprot id: A0A7U4DP36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

577650:DESPR RS15020
gene id: 577650:DESPR_RS15020
uniprot id: A0A7U3YPH7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS11350
gene id: 577650:DESPR_RS11350
uniprot id: A0A7U3YN29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

577650:DESPR RS02555
gene id: 577650:DESPR_RS02555
uniprot id: A0A7U4DN52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

577650:DESPR RS03850
gene id: 577650:DESPR_RS03850
uniprot id: A0A7U3YKA0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

577650:DESPR RS09370
gene id: 577650:DESPR_RS09370
uniprot id: A0A7U3YMB3
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

577650:DESPR RS02995
gene id: 577650:DESPR_RS02995
uniprot id: A0A7U3YJZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

577650:DESPR RS14375
gene id: 577650:DESPR_RS14375
uniprot id: A0A7U4DQE0
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

577650:DESPR RS13510
gene id: 577650:DESPR_RS13510
uniprot id: A0A7U3YNV4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

577650:DESPR RS06350
gene id: 577650:DESPR_RS06350
uniprot id: A0A7U4DNY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS09930
gene id: 577650:DESPR_RS09930
uniprot id: A0A7U4DPJ9
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS13980
gene id: 577650:DESPR_RS13980
uniprot id: A0A7U3YP16
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

577650:DESPR RS05915
gene id: 577650:DESPR_RS05915
uniprot id: A0A7U3YL22
names: Similarity
messages: Belongs to the universal stress protein A family.

577650:DESPR RS17480
gene id: 577650:DESPR_RS17480
uniprot id: A0A7U3YP80
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS14160
gene id: 577650:DESPR_RS14160
uniprot id: A0A7U3YP52
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS09605
gene id: 577650:DESPR_RS09605
uniprot id: A0A7U3YME8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

577650:DESPR RS15970
gene id: 577650:DESPR_RS15970
uniprot id: A0A7U4DQP5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

577650:DESPR RS11145
gene id: 577650:DESPR_RS11145
uniprot id: A0A7U3YN03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

577650:DESPR RS10965
gene id: 577650:DESPR_RS10965
uniprot id: A0A7U4DPU9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

577650:DESPR RS00320
gene id: 577650:DESPR_RS00320
uniprot id: A0A7U3YIY6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

577650:DESPR RS06255
gene id: 577650:DESPR_RS06255
uniprot id: A0A7U3YLH6
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS12710
gene id: 577650:DESPR_RS12710
uniprot id: A0A7U3YNK7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

577650:DESPR RS11290
gene id: 577650:DESPR_RS11290
uniprot id: A0A7U3YN30
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

577650:DESPR RS13170
gene id: 577650:DESPR_RS13170
uniprot id: A0A7U4DQ56
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

577650:DESPR RS16635
gene id: 577650:DESPR_RS16635
uniprot id: A0A7U4DQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

577650:DESPR RS14870
gene id: 577650:DESPR_RS14870
uniprot id: A0A7U3YPD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

577650:DESPR RS05280
gene id: 577650:DESPR_RS05280
uniprot id: A0A7U3YKU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

577650:DESPR RS04280
gene id: 577650:DESPR_RS04280
uniprot id: A0A7U3YKH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

577650:DESPR RS09555
gene id: 577650:DESPR_RS09555
uniprot id: A0A7U4DPH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS13690
gene id: 577650:DESPR_RS13690
uniprot id: A0A7U4DQ87
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

577650:DESPR RS14645
gene id: 577650:DESPR_RS14645
uniprot id: A0A7U3YP94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

577650:DESPR RS07000
gene id: 577650:DESPR_RS07000
uniprot id: A0A7U3YLH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

577650:DESPR RS12410
gene id: 577650:DESPR_RS12410
uniprot id: A0A7U4DPX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

577650:DESPR RS00230
gene id: 577650:DESPR_RS00230
uniprot id: A0A7U4DMR0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

577650:DESPR RS11520
gene id: 577650:DESPR_RS11520
uniprot id: A0A7U3YN50
names: Similarity
messages: Belongs to the leucine-binding protein family.

577650:DESPR RS09375
gene id: 577650:DESPR_RS09375
uniprot id: A0A7U3YMB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

577650:DESPR RS14125
gene id: 577650:DESPR_RS14125
uniprot id: A0A7U3YP30
names: Similarity
messages: Belongs to the phosphohexose mutase family.

577650:DESPR RS14705
gene id: 577650:DESPR_RS14705
uniprot id: A0A7U3YPA2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

577650:DESPR RS08890
gene id: 577650:DESPR_RS08890
uniprot id: A0A7U4DPC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

577650:DESPR RS04295
gene id: 577650:DESPR_RS04295
uniprot id: A0A7U4DNE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS08670
gene id: 577650:DESPR_RS08670
uniprot id: A0A7U4DPB5
names: Similarity
messages: Belongs to the UPF0166 family.

577650:DESPR RS08835
gene id: 577650:DESPR_RS08835
uniprot id: A0A7U4DP95
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

577650:DESPR RS07370
gene id: 577650:DESPR_RS07370
uniprot id: A0A7U3YLL5
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS03995
gene id: 577650:DESPR_RS03995
uniprot id: A0A7U4DNC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

577650:DESPR RS14530
gene id: 577650:DESPR_RS14530
uniprot id: A0A7U3YP97
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.

577650:DESPR RS12895
gene id: 577650:DESPR_RS12895
uniprot id: A0A7U3YNM4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

577650:DESPR RS08975
gene id: 577650:DESPR_RS08975
uniprot id: A0A7U4DPD6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

577650:DESPR RS00010
gene id: 577650:DESPR_RS00010
uniprot id: A0A7U4DMP7
names: Similarity
messages: Belongs to the ParB family.

577650:DESPR RS09310
gene id: 577650:DESPR_RS09310
uniprot id: A0A7U4DPD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS11990
gene id: 577650:DESPR_RS11990
uniprot id: A0A7U3YNC0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

577650:DESPR RS00695
gene id: 577650:DESPR_RS00695
uniprot id: A0A7U3YJ41
names: Subcellular Location Annotation
messages: Cytoplasm

577650:DESPR RS06410
gene id: 577650:DESPR_RS06410
uniprot id: A0A7U3YLJ6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

577650:DESPR RS02990
gene id: 577650:DESPR_RS02990
uniprot id: A0A7U3YJZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS06300
gene id: 577650:DESPR_RS06300
uniprot id: A0A7U3YL73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

577650:DESPR RS02560
gene id: 577650:DESPR_RS02560
uniprot id: A0A7U3YK28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

577650:DESPR RS00395
gene id: 577650:DESPR_RS00395
uniprot id: A0A7U4DMV2
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS14245
gene id: 577650:DESPR_RS14245
uniprot id: A0A7U3YP71
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

577650:DESPR RS04400
gene id: 577650:DESPR_RS04400
uniprot id: A0A7U4DNI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

577650:DESPR RS09915
gene id: 577650:DESPR_RS09915
uniprot id: A0A7U3YMK3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

577650:DESPR RS14560
gene id: 577650:DESPR_RS14560
uniprot id: A0A7U3YPA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

577650:DESPR RS10985
gene id: 577650:DESPR_RS10985
uniprot id: A0A7U4DPP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

577650:DESPR RS15570
gene id: 577650:DESPR_RS15570
uniprot id: A0A7U4DQL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

577650:DESPR RS09925
gene id: 577650:DESPR_RS09925
uniprot id: A0A7U3YMK5
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS07630
gene id: 577650:DESPR_RS07630
uniprot id: A0A7U3YLR0
names: Similarity
messages: Belongs to the arginase family.

577650:DESPR RS11640
gene id: 577650:DESPR_RS11640
uniprot id: A0A7U4DPV9
names: Similarity
messages: Belongs to the GSP E family.

577650:DESPR RS07095
gene id: 577650:DESPR_RS07095
uniprot id: A0A7U3YLH0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

577650:DESPR RS16665
gene id: 577650:DESPR_RS16665
uniprot id: A0A7U4DQV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

577650:DESPR RS14895
gene id: 577650:DESPR_RS14895
uniprot id: A0A7U4DQG5
names: Similarity
messages: Belongs to the UPF0047 family.

577650:DESPR RS04310
gene id: 577650:DESPR_RS04310
uniprot id: A0A7U3YKG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS04685
gene id: 577650:DESPR_RS04685
uniprot id: A0A7U3YKL5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

577650:DESPR RS14060
gene id: 577650:DESPR_RS14060
uniprot id: A0A7U3YP24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS04090
gene id: 577650:DESPR_RS04090
uniprot id: A0A7U3YKD5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

577650:DESPR RS02895
gene id: 577650:DESPR_RS02895
uniprot id: A0A7U3YJY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

577650:DESPR RS16515
gene id: 577650:DESPR_RS16515
uniprot id: A0A7U3YQ78
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

577650:DESPR RS04505
gene id: 577650:DESPR_RS04505
uniprot id: A0A7U3YKJ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS14385
gene id: 577650:DESPR_RS14385
uniprot id: A0A7U4DQA7
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

577650:DESPR RS08735
gene id: 577650:DESPR_RS08735
uniprot id: A0A7U3YM44
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

577650:DESPR RS05655
gene id: 577650:DESPR_RS05655
uniprot id: A0A7U4DNP5
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS09045
gene id: 577650:DESPR_RS09045
uniprot id: A0A7U3YMJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

577650:DESPR RS11555
gene id: 577650:DESPR_RS11555
uniprot id: A0A7U3YN58
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS15015
gene id: 577650:DESPR_RS15015
uniprot id: A0A7U3YPE0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

577650:DESPR RS09050
gene id: 577650:DESPR_RS09050
uniprot id: A0A7U4DPE1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

577650:DESPR RS11775
gene id: 577650:DESPR_RS11775
uniprot id: A0A7U4DPZ8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

577650:DESPR RS06585
gene id: 577650:DESPR_RS06585
uniprot id: A0A7U3YLC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS14470
gene id: 577650:DESPR_RS14470
uniprot id: A0A7U3YP70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

577650:DESPR RS09425
gene id: 577650:DESPR_RS09425
uniprot id: A0A7U4DPG2
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

577650:DESPR RS08955
gene id: 577650:DESPR_RS08955
uniprot id: A0A7U3YM73
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.

577650:DESPR RS03055
gene id: 577650:DESPR_RS03055
uniprot id: A0A7U4DN79
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

577650:DESPR RS15190
gene id: 577650:DESPR_RS15190
uniprot id: A0A7U3YPG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

577650:DESPR RS14840
gene id: 577650:DESPR_RS14840
uniprot id: A0A7U4DQD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS04040
gene id: 577650:DESPR_RS04040
uniprot id: A0A7U4DNF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

577650:DESPR RS02095
gene id: 577650:DESPR_RS02095
uniprot id: A0A7U3YJS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

577650:DESPR RS09830
gene id: 577650:DESPR_RS09830
uniprot id: A0A7U3YMH7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

577650:DESPR RS01830
gene id: 577650:DESPR_RS01830
uniprot id: A0A7U3YJI8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

577650:DESPR RS11550
gene id: 577650:DESPR_RS11550
uniprot id: A0A7U3YN57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS05910
gene id: 577650:DESPR_RS05910
uniprot id: A0A7U3YL25
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

577650:DESPR RS07905
gene id: 577650:DESPR_RS07905
uniprot id: A0A7U3YM46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

577650:DESPR RS10030
gene id: 577650:DESPR_RS10030
uniprot id: A0A7U3YML1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

577650:DESPR RS04145
gene id: 577650:DESPR_RS04145
uniprot id: A0A7U3YKE3
names: Similarity
messages: Belongs to the histone deacetylase family.

577650:DESPR RS09420
gene id: 577650:DESPR_RS09420
uniprot id: A0A7U3YMN4
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

577650:DESPR RS06790
gene id: 577650:DESPR_RS06790
uniprot id: A0A7U3YLC9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

577650:DESPR RS05385
gene id: 577650:DESPR_RS05385
uniprot id: A0A7U3YL38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

577650:DESPR RS06245
gene id: 577650:DESPR_RS06245
uniprot id: A0A7U3YL60
names: Similarity
messages: Belongs to the universal stress protein A family.

577650:DESPR RS01620
gene id: 577650:DESPR_RS01620
uniprot id: A0A7U3YJ18
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

577650:DESPR RS03540
gene id: 577650:DESPR_RS03540
uniprot id: A0A7U4DNC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

577650:DESPR RS06075
gene id: 577650:DESPR_RS06075
uniprot id: A0A7U4DNS5
names: Similarity
messages: Belongs to the Lgt family.

577650:DESPR RS10010
gene id: 577650:DESPR_RS10010
uniprot id: A0A7U4DPK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

577650:DESPR RS01365
gene id: 577650:DESPR_RS01365
uniprot id: A0A7U3YJG6
names: Similarity
messages: Belongs to the citrate synthase family.

577650:DESPR RS15995
gene id: 577650:DESPR_RS15995
uniprot id: A0A7U4DQS3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

577650:DESPR RS03775
gene id: 577650:DESPR_RS03775
uniprot id: A0A7U3YKH7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

577650:DESPR RS08580
gene id: 577650:DESPR_RS08580
uniprot id: A0A7U3YM17
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

577650:DESPR RS02720
gene id: 577650:DESPR_RS02720
uniprot id: A0A7U3YK47
names: Similarity
messages: Belongs to the polysaccharide synthase family.

577650:DESPR RS07100
gene id: 577650:DESPR_RS07100
uniprot id: A0A7U4DP18
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

577650:DESPR RS06815
gene id: 577650:DESPR_RS06815
uniprot id: A0A7U4DNX1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

577650:DESPR RS09400
gene id: 577650:DESPR_RS09400
uniprot id: A0A7U3YMD6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS14875
gene id: 577650:DESPR_RS14875
uniprot id: A0A7U3YPC0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

577650:DESPR RS14015
gene id: 577650:DESPR_RS14015
uniprot id: A0A7U3YP34
names: Similarity
messages: Belongs to the YicC/YloC family.

577650:DESPR RS16440
gene id: 577650:DESPR_RS16440
uniprot id: A0A7U3YQ73
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

577650:DESPR RS09800
gene id: 577650:DESPR_RS09800
uniprot id: A0A7U4DPF8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

577650:DESPR RS10295
gene id: 577650:DESPR_RS10295
uniprot id: A0A7U3YMQ4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

577650:DESPR RS05515
gene id: 577650:DESPR_RS05515
uniprot id: A0A7U3YKY1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

577650:DESPR RS15600
gene id: 577650:DESPR_RS15600
uniprot id: A0A7U3YPN6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

577650:DESPR RS01430
gene id: 577650:DESPR_RS01430
uniprot id: A0A7U3YJN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

577650:DESPR RS04675
gene id: 577650:DESPR_RS04675
uniprot id: A0A7U3YKM9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS10370
gene id: 577650:DESPR_RS10370
uniprot id: A0A7U3YMR2
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS15175
gene id: 577650:DESPR_RS15175
uniprot id: A0A7U3YPG7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

577650:DESPR RS16555
gene id: 577650:DESPR_RS16555
uniprot id: A0A7U4DQN7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

577650:DESPR RS17110
gene id: 577650:DESPR_RS17110
uniprot id: A0A7U3YKZ8
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS13015
gene id: 577650:DESPR_RS13015
uniprot id: A0A7U4DQ72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

577650:DESPR RS17190
gene id: 577650:DESPR_RS17190
uniprot id: A0A7U4DP21
names: Similarity
messages: Belongs to the peptidase C40 family.

577650:DESPR RS08475
gene id: 577650:DESPR_RS08475
uniprot id: A0A7U4DP80
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

577650:DESPR RS03620
gene id: 577650:DESPR_RS03620
uniprot id: A0A7U4DND5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

577650:DESPR RS14945
gene id: 577650:DESPR_RS14945
uniprot id: A0A7U3YPD0
names: Similarity
messages: Belongs to the pyruvate kinase family.

577650:DESPR RS04005
gene id: 577650:DESPR_RS04005
uniprot id: A0A7U3YKC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

577650:DESPR RS07540
gene id: 577650:DESPR_RS07540
uniprot id: A0A7U3YLN5
names: Similarity
messages: Belongs to the CutA family.

577650:DESPR RS06870
gene id: 577650:DESPR_RS06870
uniprot id: A0A7U3YLQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

577650:DESPR RS01155
gene id: 577650:DESPR_RS01155
uniprot id: A0A7U3YJ98
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

577650:DESPR RS01420
gene id: 577650:DESPR_RS01420
uniprot id: A0A7U3YJD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

577650:DESPR RS04830
gene id: 577650:DESPR_RS04830
uniprot id: A0A7U3YKP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

577650:DESPR RS13965
gene id: 577650:DESPR_RS13965
uniprot id: A0A7U3YP26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

577650:DESPR RS10260
gene id: 577650:DESPR_RS10260
uniprot id: A0A7U3YMP4
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS12970
gene id: 577650:DESPR_RS12970
uniprot id: A0A7U3YNN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

577650:DESPR RS07825
gene id: 577650:DESPR_RS07825
uniprot id: A0A7U3YM35
names: Similarity
messages: Belongs to the UPF0246 family.

577650:DESPR RS10410
gene id: 577650:DESPR_RS10410
uniprot id: A0A7U3YMR5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

577650:DESPR RS13280
gene id: 577650:DESPR_RS13280
uniprot id: A0A7U3YNS8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

577650:DESPR RS06430
gene id: 577650:DESPR_RS06430
uniprot id: A0A7U4DNU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

577650:DESPR RS09795
gene id: 577650:DESPR_RS09795
uniprot id: A0A7U3YMJ7
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

577650:DESPR RS02575
gene id: 577650:DESPR_RS02575
uniprot id: A0A7U4DN60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

577650:DESPR RS13225
gene id: 577650:DESPR_RS13225
uniprot id: A0A7U4DQ57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

577650:DESPR RS00400
gene id: 577650:DESPR_RS00400
uniprot id: A0A7U3YIZ4
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS07470
gene id: 577650:DESPR_RS07470
uniprot id: A0A7U3YLM1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

577650:DESPR RS07750
gene id: 577650:DESPR_RS07750
uniprot id: A0A7U3YM27
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

577650:DESPR RS16685
gene id: 577650:DESPR_RS16685
uniprot id: A0A7U4DQQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

577650:DESPR RS14540
gene id: 577650:DESPR_RS14540
uniprot id: A0A7U3YPA9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

577650:DESPR RS04105
gene id: 577650:DESPR_RS04105
uniprot id: A0A7U4DNG6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

577650:DESPR RS05210
gene id: 577650:DESPR_RS05210
uniprot id: A0A7U3YKT0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

577650:DESPR RS16630
gene id: 577650:DESPR_RS16630
uniprot id: A0A7U3YQ19
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

577650:DESPR RS09215
gene id: 577650:DESPR_RS09215
uniprot id: A0A7U4DPH5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

577650:DESPR RS09055
gene id: 577650:DESPR_RS09055
uniprot id: A0A7U3YM90
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

577650:DESPR RS02860
gene id: 577650:DESPR_RS02860
uniprot id: A0A7U4DN71
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

577650:DESPR RS14680
gene id: 577650:DESPR_RS14680
uniprot id: A0A7U4DQF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

577650:DESPR RS06535
gene id: 577650:DESPR_RS06535
uniprot id: A0A7U4DNV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

577650:DESPR RS11575
gene id: 577650:DESPR_RS11575
uniprot id: A0A7U4DPV0
names: Similarity
messages: Belongs to the peptidase S1C family.

577650:DESPR RS02260
gene id: 577650:DESPR_RS02260
uniprot id: A0A7U3YJU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS03145
gene id: 577650:DESPR_RS03145
uniprot id: A0A7U3YK15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

577650:DESPR RS04080
gene id: 577650:DESPR_RS04080
uniprot id: A0A7U3YKD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

577650:DESPR RS19170
gene id: 577650:DESPR_RS19170
uniprot id: A0A7U3YMV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

577650:DESPR RS11480
gene id: 577650:DESPR_RS11480
uniprot id: A0A7U3YN45
names: Similarity
messages: Belongs to the glutamate synthase family.

577650:DESPR RS01630
gene id: 577650:DESPR_RS01630
uniprot id: A0A7U3YJF8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

577650:DESPR RS10465
gene id: 577650:DESPR_RS10465
uniprot id: A0A7U4DPK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS13545
gene id: 577650:DESPR_RS13545
uniprot id: A0A7U3YNW4
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

577650:DESPR RS09155
gene id: 577650:DESPR_RS09155
uniprot id: A0A7U4DPC3
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

577650:DESPR RS04100
gene id: 577650:DESPR_RS04100
uniprot id: A0A7U3YKL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

577650:DESPR RS16590
gene id: 577650:DESPR_RS16590
uniprot id: A0A7U4DQV1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

577650:DESPR RS15685
gene id: 577650:DESPR_RS15685
uniprot id: A0A7U3YPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

577650:DESPR RS11170
gene id: 577650:DESPR_RS11170
uniprot id: A0A7U3YNA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

577650:DESPR RS02405
gene id: 577650:DESPR_RS02405
uniprot id: A0A7U4DN55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

577650:DESPR RS02550
gene id: 577650:DESPR_RS02550
uniprot id: A0A7U3YJT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS04430
gene id: 577650:DESPR_RS04430
uniprot id: A0A7U3YKI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

577650:DESPR RS07535
gene id: 577650:DESPR_RS07535
uniprot id: A0A7U4DP56
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS02480
gene id: 577650:DESPR_RS02480
uniprot id: A0A7U4DN47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

577650:DESPR RS16625
gene id: 577650:DESPR_RS16625
uniprot id: A0A7U3YPZ6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

577650:DESPR RS10415
gene id: 577650:DESPR_RS10415
uniprot id: A0A7U4DPK5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

577650:DESPR RS13400
gene id: 577650:DESPR_RS13400
uniprot id: A0A7U4DQ99
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

577650:DESPR RS19100
gene id: 577650:DESPR_RS19100
uniprot id: A0A7U3YPI4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

577650:DESPR RS17295
gene id: 577650:DESPR_RS17295
uniprot id: A0A7U3YMF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

577650:DESPR RS16255
gene id: 577650:DESPR_RS16255
uniprot id: A0A7U3YPV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS04020
gene id: 577650:DESPR_RS04020
uniprot id: A0A7U4DNF6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

577650:DESPR RS09535
gene id: 577650:DESPR_RS09535
uniprot id: A0A7U3YME3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

577650:DESPR RS04465
gene id: 577650:DESPR_RS04465
uniprot id: A0A7U4DNI7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

577650:DESPR RS06885
gene id: 577650:DESPR_RS06885
uniprot id: A0A7U4DNX7
names: Similarity
messages: Belongs to the leucine-binding protein family.

577650:DESPR RS05320
gene id: 577650:DESPR_RS05320
uniprot id: A0A7U3YKX7
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS08380
gene id: 577650:DESPR_RS08380
uniprot id: A0A7U4DPB6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

577650:DESPR RS05375
gene id: 577650:DESPR_RS05375
uniprot id: A0A7U3YKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

577650:DESPR RS04220
gene id: 577650:DESPR_RS04220
uniprot id: A0A7U3YKF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

577650:DESPR RS15220
gene id: 577650:DESPR_RS15220
uniprot id: A0A7U4DQM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS13940
gene id: 577650:DESPR_RS13940
uniprot id: A0A7U3YP14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS11610
gene id: 577650:DESPR_RS11610
uniprot id: A0A7U4DPS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

577650:DESPR RS10930
gene id: 577650:DESPR_RS10930
uniprot id: A0A7U3YMY3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS13330
gene id: 577650:DESPR_RS13330
uniprot id: A0A7U3YNT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

577650:DESPR RS07260
gene id: 577650:DESPR_RS07260
uniprot id: A0A7U3YLJ3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

577650:DESPR RS04085
gene id: 577650:DESPR_RS04085
uniprot id: A0A7U3YKD4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS15835
gene id: 577650:DESPR_RS15835
uniprot id: A0A7U4DQK4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

577650:DESPR RS15025
gene id: 577650:DESPR_RS15025
uniprot id: A0A7U3YPG3
names: Similarity
messages: Belongs to the SUI1 family.

577650:DESPR RS06625
gene id: 577650:DESPR_RS06625
uniprot id: A0A7U3YLB7
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS06355
gene id: 577650:DESPR_RS06355
uniprot id: A0A7U3YL80
names: Subunit
messages: Heterodimer of a large and a small subunit.

577650:DESPR RS13230
gene id: 577650:DESPR_RS13230
uniprot id: A0A7U3YP10
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

577650:DESPR RS09775
gene id: 577650:DESPR_RS09775
uniprot id: A0A7U3YMI4
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

577650:DESPR RS02455
gene id: 577650:DESPR_RS02455
uniprot id: A0A7U3YJT2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

577650:DESPR RS16480
gene id: 577650:DESPR_RS16480
uniprot id: A0A7U4DQN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS10220
gene id: 577650:DESPR_RS10220
uniprot id: A0A7U3YMP5
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS10310
gene id: 577650:DESPR_RS10310
uniprot id: A0A7U3YN00
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

577650:DESPR RS08985
gene id: 577650:DESPR_RS08985
uniprot id: A0A7U4DPA3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

577650:DESPR RS09475
gene id: 577650:DESPR_RS09475
uniprot id: A0A7U3YME0
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

577650:DESPR RS08655
gene id: 577650:DESPR_RS08655
uniprot id: A0A7U3YM37
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

577650:DESPR RS04570
gene id: 577650:DESPR_RS04570
uniprot id: A0A7U3YKK3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

577650:DESPR RS01160
gene id: 577650:DESPR_RS01160
uniprot id: A0A7U3YJB3
names: Similarity
messages: Belongs to the ModE family.

577650:DESPR RS04980
gene id: 577650:DESPR_RS04980
uniprot id: A0A7U3YKR7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

577650:DESPR RS04180
gene id: 577650:DESPR_RS04180
uniprot id: A0A7U4DNH2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

577650:DESPR RS14490
gene id: 577650:DESPR_RS14490
uniprot id: A0A7U3YP91
names: Similarity
messages: Belongs to the glutamate synthase family.

577650:DESPR RS03870
gene id: 577650:DESPR_RS03870
uniprot id: A0A7U4DNE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

577650:DESPR RS04275
gene id: 577650:DESPR_RS04275
uniprot id: A0A7U4DNL1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

577650:DESPR RS08725
gene id: 577650:DESPR_RS08725
uniprot id: A0A7U3YM41
names: Similarity
messages: Belongs to the HypD family.

577650:DESPR RS16100
gene id: 577650:DESPR_RS16100
uniprot id: A0A7U3YPU1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

577650:DESPR RS11510
gene id: 577650:DESPR_RS11510
uniprot id: A0A7U4DPS1
names: Similarity
messages: Belongs to the universal stress protein A family.

577650:DESPR RS14320
gene id: 577650:DESPR_RS14320
uniprot id: A0A7U3YP79
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

577650:DESPR RS02290
gene id: 577650:DESPR_RS02290
uniprot id: A0A7U4DN22
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

577650:DESPR RS10130
gene id: 577650:DESPR_RS10130
uniprot id: A0A7U3YMM2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

577650:DESPR RS17065
gene id: 577650:DESPR_RS17065
uniprot id: A0A7U3YKS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

577650:DESPR RS07250
gene id: 577650:DESPR_RS07250
uniprot id: A0A7U4DNZ6
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

577650:DESPR RS11235
gene id: 577650:DESPR_RS11235
uniprot id: A0A7U3YN17
names: Similarity
messages: Belongs to the FlgM family.

577650:DESPR RS06200
gene id: 577650:DESPR_RS06200
uniprot id: A0A7U4DNS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS09760
gene id: 577650:DESPR_RS09760
uniprot id: A0A7U3YMH1
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

577650:DESPR RS12435
gene id: 577650:DESPR_RS12435
uniprot id: A0A7U3YNH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

577650:DESPR RS07315
gene id: 577650:DESPR_RS07315
uniprot id: A0A7U3YLK1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

577650:DESPR RS05960
gene id: 577650:DESPR_RS05960
uniprot id: A0A7U4DNV7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

577650:DESPR RS05890
gene id: 577650:DESPR_RS05890
uniprot id: A0A7U3YL23
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

577650:DESPR RS03110
gene id: 577650:DESPR_RS03110
uniprot id: A0A7U4DNE0
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

577650:DESPR RS09845
gene id: 577650:DESPR_RS09845
uniprot id: A0A7U3YMJ4
names: Similarity
messages: Belongs to the cytochrome c-552 family.

577650:DESPR RS00070
gene id: 577650:DESPR_RS00070
uniprot id: A0A7U3YJ64
names: Similarity
messages: Belongs to the peptidase A31 family.

577650:DESPR RS02400
gene id: 577650:DESPR_RS02400
uniprot id: A0A7U3YK05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

577650:DESPR RS02435
gene id: 577650:DESPR_RS02435
uniprot id: A0A7U3YJS2
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

577650:DESPR RS12060
gene id: 577650:DESPR_RS12060
uniprot id: A0A7U4DPY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

577650:DESPR RS06915
gene id: 577650:DESPR_RS06915
uniprot id: A0A7U3YLF2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

577650:DESPR RS04165
gene id: 577650:DESPR_RS04165
uniprot id: A0A7U3YKE5
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS08395
gene id: 577650:DESPR_RS08395
uniprot id: A0A7U3YM06
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS07795
gene id: 577650:DESPR_RS07795
uniprot id: A0A7U3YLR4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

577650:DESPR RS04345
gene id: 577650:DESPR_RS04345
uniprot id: A0A7U4DNG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS15855
gene id: 577650:DESPR_RS15855
uniprot id: A0A7U3YPS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

577650:DESPR RS04860
gene id: 577650:DESPR_RS04860
uniprot id: A0A7U3YKS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

577650:DESPR RS15030
gene id: 577650:DESPR_RS15030
uniprot id: A0A7U3YPE9
names: Similarity
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.

577650:DESPR RS04655
gene id: 577650:DESPR_RS04655
uniprot id: A0A7U3YKL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

577650:DESPR RS01900
gene id: 577650:DESPR_RS01900
uniprot id: A0A7U3YJK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

577650:DESPR RS03645
gene id: 577650:DESPR_RS03645
uniprot id: A0A7U3YK82
names: Similarity
messages: Belongs to the citrate synthase family.

577650:DESPR RS09020
gene id: 577650:DESPR_RS09020
uniprot id: A0A7U3YM75
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Belongs to the GARS family.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

577650:DESPR RS16060
gene id: 577650:DESPR_RS16060
uniprot id: A0A7U3YPT8
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS07645
gene id: 577650:DESPR_RS07645
uniprot id: A0A7U3YLP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

577650:DESPR RS02805
gene id: 577650:DESPR_RS02805
uniprot id: A0A7U4DN73
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

577650:DESPR RS03770
gene id: 577650:DESPR_RS03770
uniprot id: A0A7U4DNE3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

577650:DESPR RS18650
gene id: 577650:DESPR_RS18650
uniprot id: A0A7U3YPX0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

577650:DESPR RS03865
gene id: 577650:DESPR_RS03865
uniprot id: A0A7U3YKA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

577650:DESPR RS08080
gene id: 577650:DESPR_RS08080
uniprot id: A0A7U3YLT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

577650:DESPR RS09085
gene id: 577650:DESPR_RS09085
uniprot id: A0A7U4DPB7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

577650:DESPR RS06910
gene id: 577650:DESPR_RS06910
uniprot id: A0A7U4DNX8
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS06180
gene id: 577650:DESPR_RS06180
uniprot id: A0A7U4DNV0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

577650:DESPR RS11245
gene id: 577650:DESPR_RS11245
uniprot id: A0A7U3YNB9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

577650:DESPR RS11015
gene id: 577650:DESPR_RS11015
uniprot id: A0A7U4DPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

577650:DESPR RS00190
gene id: 577650:DESPR_RS00190
uniprot id: A0A7U4DMI9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

577650:DESPR RS11330
gene id: 577650:DESPR_RS11330
uniprot id: A0A7U4DPT3
names: Similarity
messages: Belongs to the UPF0751 family.

577650:DESPR RS04590
gene id: 577650:DESPR_RS04590
uniprot id: A0A7U4DNH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

577650:DESPR RS02155
gene id: 577650:DESPR_RS02155
uniprot id: A0A7U4DN30
names: Similarity
messages: Belongs to the hemerythrin family.

577650:DESPR RS15170
gene id: 577650:DESPR_RS15170
uniprot id: A0A7U3YPH1
names: Similarity
messages: Belongs to the CobH/CbiC family.

577650:DESPR RS15785
gene id: 577650:DESPR_RS15785
uniprot id: A0A7U4DQI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

577650:DESPR RS04645
gene id: 577650:DESPR_RS04645
uniprot id: A0A7U3YKL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

577650:DESPR RS05420
gene id: 577650:DESPR_RS05420
uniprot id: A0A7U3YKW0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS11935
gene id: 577650:DESPR_RS11935
uniprot id: A0A7U3YNA1
names: Similarity
messages: Belongs to the UPF0102 family.

577650:DESPR RS11565
gene id: 577650:DESPR_RS11565
uniprot id: A0A7U4DPV5
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS13135
gene id: 577650:DESPR_RS13135
uniprot id: A0A7U3YNS5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

577650:DESPR RS06130
gene id: 577650:DESPR_RS06130
uniprot id: A0A7U3YL55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

577650:DESPR RS00175
gene id: 577650:DESPR_RS00175
uniprot id: A0A7U3YIV8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

577650:DESPR RS13905
gene id: 577650:DESPR_RS13905
uniprot id: A0A7U3YP03
names: Similarity
messages: Belongs to the ClpA/ClpB family.

577650:DESPR RS11040
gene id: 577650:DESPR_RS11040
uniprot id: A0A7U4DPV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS04540
gene id: 577650:DESPR_RS04540
uniprot id: A0A7U4DNJ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS07070
gene id: 577650:DESPR_RS07070
uniprot id: A0A7U3YLG8
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

577650:DESPR RS05475
gene id: 577650:DESPR_RS05475
uniprot id: A0A7U4DNN2
names: Similarity
messages: Belongs to the oxoprolinase family.

577650:DESPR RS09820
gene id: 577650:DESPR_RS09820
uniprot id: A0A7U3YMI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

577650:DESPR RS08050
gene id: 577650:DESPR_RS08050
uniprot id: A0A7U4DP75
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

577650:DESPR RS15920
gene id: 577650:DESPR_RS15920
uniprot id: A0A7U3YPS4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

577650:DESPR RS14055
gene id: 577650:DESPR_RS14055
uniprot id: A0A7U3YP21
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

577650:DESPR RS05315
gene id: 577650:DESPR_RS05315
uniprot id: A0A7U4DNQ2
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS05115
gene id: 577650:DESPR_RS05115
uniprot id: A0A7U3YKS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

577650:DESPR RS11625
gene id: 577650:DESPR_RS11625
uniprot id: A0A7U3YN68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

577650:DESPR RS09140
gene id: 577650:DESPR_RS09140
uniprot id: A0A7U3YM82
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

577650:DESPR RS05190
gene id: 577650:DESPR_RS05190
uniprot id: A0A7U3YKT1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

577650:DESPR RS07485
gene id: 577650:DESPR_RS07485
uniprot id: A0A7U3YLL8
names: Similarity
messages: Belongs to the citrate synthase family.

577650:DESPR RS09990
gene id: 577650:DESPR_RS09990
uniprot id: A0A7U3YMK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

577650:DESPR RS11900
gene id: 577650:DESPR_RS11900
uniprot id: A0A7U4DPX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

577650:DESPR RS04565
gene id: 577650:DESPR_RS04565
uniprot id: A0A7U4DNN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

577650:DESPR RS04335
gene id: 577650:DESPR_RS04335
uniprot id: A0A7U4DNI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

577650:DESPR RS08025
gene id: 577650:DESPR_RS08025
uniprot id: A0A7U3YLT9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

577650:DESPR RS11975
gene id: 577650:DESPR_RS11975
uniprot id: A0A7U4DPX8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

577650:DESPR RS10280
gene id: 577650:DESPR_RS10280
uniprot id: A0A7U3YMN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS03845
gene id: 577650:DESPR_RS03845
uniprot id: A0A7U3YKA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

577650:DESPR RS15240
gene id: 577650:DESPR_RS15240
uniprot id: A0A7U4DQF3
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

577650:DESPR RS07005
gene id: 577650:DESPR_RS07005
uniprot id: A0A7U3YLF8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

577650:DESPR RS09705
gene id: 577650:DESPR_RS09705
uniprot id: A0A7U4DPI8
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS15510
gene id: 577650:DESPR_RS15510
uniprot id: A0A7U3YPM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS07500
gene id: 577650:DESPR_RS07500
uniprot id: A0A7U3YLN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

577650:DESPR RS08455
gene id: 577650:DESPR_RS08455
uniprot id: A0A7U4DPC1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

577650:DESPR RS13715
gene id: 577650:DESPR_RS13715
uniprot id: A0A7U4DQB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

577650:DESPR RS03915
gene id: 577650:DESPR_RS03915
uniprot id: A0A7U4DNC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

577650:DESPR RS00245
gene id: 577650:DESPR_RS00245
uniprot id: A0A7U4DMU2
names: Similarity
messages: Belongs to the bacterial glucokinase family.

577650:DESPR RS03585
gene id: 577650:DESPR_RS03585
uniprot id: A0A7U3YK73
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

577650:DESPR RS12085
gene id: 577650:DESPR_RS12085
uniprot id: A0A7U3YNC9
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

577650:DESPR RS14120
gene id: 577650:DESPR_RS14120
uniprot id: A0A7U3YP39
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

577650:DESPR RS03590
gene id: 577650:DESPR_RS03590
uniprot id: A0A7U3YK70
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

577650:DESPR RS13515
gene id: 577650:DESPR_RS13515
uniprot id: A0A7U3YNV9
names: Similarity
messages: Belongs to the FUN14 family.

577650:DESPR RS08935
gene id: 577650:DESPR_RS08935
uniprot id: A0A7U4DPA7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

577650:DESPR RS14050
gene id: 577650:DESPR_RS14050
uniprot id: A0A7U3YP31
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

577650:DESPR RS04035
gene id: 577650:DESPR_RS04035
uniprot id: A0A7U3YKG7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

577650:DESPR RS16225
gene id: 577650:DESPR_RS16225
uniprot id: A0A7U4DQM9
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS18745
gene id: 577650:DESPR_RS18745
uniprot id: A0A7U4DNE2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

577650:DESPR RS16070
gene id: 577650:DESPR_RS16070
uniprot id: A0A7U4DQS6
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS16250
gene id: 577650:DESPR_RS16250
uniprot id: A0A7U4DQL6
names: Similarity
messages: Belongs to the CinA family.

577650:DESPR RS03985
gene id: 577650:DESPR_RS03985
uniprot id: A0A7U3YKC2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

577650:DESPR RS00210
gene id: 577650:DESPR_RS00210
uniprot id: A0A7U3YIW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

577650:DESPR RS16990
gene id: 577650:DESPR_RS16990
uniprot id: A0A7U3YK87
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS03000
gene id: 577650:DESPR_RS03000
uniprot id: A0A7U3YJZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

577650:DESPR RS09825
gene id: 577650:DESPR_RS09825
uniprot id: A0A7U4DPG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

577650:DESPR RS13020
gene id: 577650:DESPR_RS13020
uniprot id: A0A7U3YNP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Membrane

577650:DESPR RS07425
gene id: 577650:DESPR_RS07425
uniprot id: A0A7U3YLK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

577650:DESPR RS15340
gene id: 577650:DESPR_RS15340
uniprot id: A0A7U3YPL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

577650:DESPR RS09995
gene id: 577650:DESPR_RS09995
uniprot id: A0A7U3YML5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

577650:DESPR RS07715
gene id: 577650:DESPR_RS07715
uniprot id: A0A7U4DP27
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

577650:DESPR RS14030
gene id: 577650:DESPR_RS14030
uniprot id: A0A7U3YP33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

577650:DESPR RS09305
gene id: 577650:DESPR_RS09305
uniprot id: A0A7U3YMB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS17290
gene id: 577650:DESPR_RS17290
uniprot id: A0A7U4DPE4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

577650:DESPR RS06280
gene id: 577650:DESPR_RS06280
uniprot id: A0A7U3YL69
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

577650:DESPR RS03415
gene id: 577650:DESPR_RS03415
uniprot id: A0A7U4DNB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

577650:DESPR RS07115
gene id: 577650:DESPR_RS07115
uniprot id: A0A7U3YLI8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

577650:DESPR RS16725
gene id: 577650:DESPR_RS16725
uniprot id: A0A7U3YQ16
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

577650:DESPR RS04795
gene id: 577650:DESPR_RS04795
uniprot id: A0A7U4DNP4
names: Similarity
messages: Belongs to the peptidase S41A family.

577650:DESPR RS16105
gene id: 577650:DESPR_RS16105
uniprot id: A0A7U3YPV0
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS02135
gene id: 577650:DESPR_RS02135
uniprot id: A0A7U3YJM8
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

577650:DESPR RS03920
gene id: 577650:DESPR_RS03920
uniprot id: A0A7U3YKB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

577650:DESPR RS16465
gene id: 577650:DESPR_RS16465
uniprot id: A0A7U3YPY1
names: Similarity
messages: Belongs to the universal stress protein A family.

577650:DESPR RS04395
gene id: 577650:DESPR_RS04395
uniprot id: A0A7U3YKH9
names: Similarity
messages: Belongs to the type IA topoisomerase family.

577650:DESPR RS11250
gene id: 577650:DESPR_RS11250
uniprot id: A0A7U4DPS8
names: Similarity
messages: Belongs to the bacterial flagellin family.

577650:DESPR RS00335
gene id: 577650:DESPR_RS00335
uniprot id: A0A7U4DMK3
names: Caution
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS11400
gene id: 577650:DESPR_RS11400
uniprot id: A0A7U3YN37
names: Similarity
messages: Belongs to the MEMO1 family.

577650:DESPR RS14685
gene id: 577650:DESPR_RS14685
uniprot id: A0A7U3YPB6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS16540
gene id: 577650:DESPR_RS16540
uniprot id: A0A7U3YPZ1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS03515
gene id: 577650:DESPR_RS03515
uniprot id: A0A7U4DNA1
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

577650:DESPR RS09715
gene id: 577650:DESPR_RS09715
uniprot id: A0A7U4DPI0
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

577650:DESPR RS04650
gene id: 577650:DESPR_RS04650
uniprot id: A0A7U3YKK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

577650:DESPR RS05220
gene id: 577650:DESPR_RS05220
uniprot id: A0A7U3YKV6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

577650:DESPR RS05830
gene id: 577650:DESPR_RS05830
uniprot id: A0A7U3YL12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

577650:DESPR RS01565
gene id: 577650:DESPR_RS01565
uniprot id: A0A7U3YJG1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS03660
gene id: 577650:DESPR_RS03660
uniprot id: A0A7U3YK83
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

577650:DESPR RS08860
gene id: 577650:DESPR_RS08860
uniprot id: A0A7U4DPA2
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

577650:DESPR RS07325
gene id: 577650:DESPR_RS07325
uniprot id: A0A7U3YLM0
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS11970
gene id: 577650:DESPR_RS11970
uniprot id: A0A7U3YNB4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

577650:DESPR RS12370
gene id: 577650:DESPR_RS12370
uniprot id: A0A7U3YNQ1
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS14690
gene id: 577650:DESPR_RS14690
uniprot id: A0A7U4DQC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

577650:DESPR RS12055
gene id: 577650:DESPR_RS12055
uniprot id: A0A7U3YNL7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

577650:DESPR RS11205
gene id: 577650:DESPR_RS11205
uniprot id: A0A7U3YN14
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

577650:DESPR RS00105
gene id: 577650:DESPR_RS00105
uniprot id: A0A7U3YIU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

577650:DESPR RS16330
gene id: 577650:DESPR_RS16330
uniprot id: A0A7U3YPW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

577650:DESPR RS14640
gene id: 577650:DESPR_RS14640
uniprot id: A0A7U3YPA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

577650:DESPR RS12065
gene id: 577650:DESPR_RS12065
uniprot id: A0A7U3YNC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

577650:DESPR RS01475
gene id: 577650:DESPR_RS01475
uniprot id: A0A7U3YJD8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

577650:DESPR RS01575
gene id: 577650:DESPR_RS01575
uniprot id: A0A7U3YJF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

577650:DESPR RS09095
gene id: 577650:DESPR_RS09095
uniprot id: A0A7U3YJ18
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

577650:DESPR RS02980
gene id: 577650:DESPR_RS02980
uniprot id: A0A7U4DN70
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

577650:DESPR RS01455
gene id: 577650:DESPR_RS01455
uniprot id: A0A7U3YJE5
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS12395
gene id: 577650:DESPR_RS12395
uniprot id: A0A7U3YNG5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

577650:DESPR RS14880
gene id: 577650:DESPR_RS14880
uniprot id: A0A7U3YPF8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

577650:DESPR RS07730
gene id: 577650:DESPR_RS07730
uniprot id: A0A7U3YLR7
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

577650:DESPR RS15095
gene id: 577650:DESPR_RS15095
uniprot id: A0A7U3YPG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

577650:DESPR RS12890
gene id: 577650:DESPR_RS12890
uniprot id: A0A7U3YNM6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

577650:DESPR RS07800
gene id: 577650:DESPR_RS07800
uniprot id: A0A7U3YLR3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

577650:DESPR RS04545
gene id: 577650:DESPR_RS04545
uniprot id: A0A7U3YKS8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

577650:DESPR RS02140
gene id: 577650:DESPR_RS02140
uniprot id: A0A7U3YJN9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

577650:DESPR RS09485
gene id: 577650:DESPR_RS09485
uniprot id: A0A7U4DPH0
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

577650:DESPR RS03895
gene id: 577650:DESPR_RS03895
uniprot id: A0A7U4DNI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

577650:DESPR RS12830
gene id: 577650:DESPR_RS12830
uniprot id: A0A7U4DQ32
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

577650:DESPR RS11740
gene id: 577650:DESPR_RS11740
uniprot id: A0A7U3YN82
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

577650:DESPR RS03785
gene id: 577650:DESPR_RS03785
uniprot id: A0A7U4DNE1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

577650:DESPR RS05205
gene id: 577650:DESPR_RS05205
uniprot id: A0A7U3YKT5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

577650:DESPR RS03580
gene id: 577650:DESPR_RS03580
uniprot id: A0A7U4DNA4
names: Similarity
messages: Belongs to the RutC family.

577650:DESPR RS11790
gene id: 577650:DESPR_RS11790
uniprot id: A0A7U3YN84
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS10235
gene id: 577650:DESPR_RS10235
uniprot id: A0A7U3YMZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS11505
gene id: 577650:DESPR_RS11505
uniprot id: A0A7U3YN63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

577650:DESPR RS14965
gene id: 577650:DESPR_RS14965
uniprot id: A0A7U3YPN8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

577650:DESPR RS10250
gene id: 577650:DESPR_RS10250
uniprot id: A0A7U4DPI9
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

577650:DESPR RS00265
gene id: 577650:DESPR_RS00265
uniprot id: A0A7U4DMJ5
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS06445
gene id: 577650:DESPR_RS06445
uniprot id: A0A7U3YL97
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

577650:DESPR RS00215
gene id: 577650:DESPR_RS00215
uniprot id: A0A7U3YIV4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

577650:DESPR RS13315
gene id: 577650:DESPR_RS13315
uniprot id: A0A7U3YNT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

577650:DESPR RS04070
gene id: 577650:DESPR_RS04070
uniprot id: A0A7U3YKD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

577650:DESPR RS03370
gene id: 577650:DESPR_RS03370
uniprot id: A0A7U3YK42
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

577650:DESPR RS15965
gene id: 577650:DESPR_RS15965
uniprot id: A0A7U3YQ39
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

577650:DESPR RS11630
gene id: 577650:DESPR_RS11630
uniprot id: A0A7U3YN66
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS14610
gene id: 577650:DESPR_RS14610
uniprot id: A0A7U4DQC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

577650:DESPR RS02760
gene id: 577650:DESPR_RS02760
uniprot id: A0A7U3YJV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

577650:DESPR RS03225
gene id: 577650:DESPR_RS03225
uniprot id: A0A7U3YK25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

577650:DESPR RS05185
gene id: 577650:DESPR_RS05185
uniprot id: A0A7U3YKS9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

577650:DESPR RS04880
gene id: 577650:DESPR_RS04880
uniprot id: A0A7U3YKP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS04630
gene id: 577650:DESPR_RS04630
uniprot id: A0A7U4DNK7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

577650:DESPR RS01920
gene id: 577650:DESPR_RS01920
uniprot id: A0A7U3YJJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

577650:DESPR RS04255
gene id: 577650:DESPR_RS04255
uniprot id: A0A7U3YKN1
names: Subcellular Location Annotation
messages: Cytoplasm

577650:DESPR RS10400
gene id: 577650:DESPR_RS10400
uniprot id: A0A7U3YMR0
names: Similarity
messages: Belongs to the AOR/FOR family.

577650:DESPR RS15820
gene id: 577650:DESPR_RS15820
uniprot id: A0A7U3YPZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS06630
gene id: 577650:DESPR_RS06630
uniprot id: A0A7U3YLC3
names: Similarity
messages: Belongs to the UPF0111 family.

577650:DESPR RS13675
gene id: 577650:DESPR_RS13675
uniprot id: A0A7U3YNY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

577650:DESPR RS11160
gene id: 577650:DESPR_RS11160
uniprot id: A0A7U3YN10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

577650:DESPR RS14850
gene id: 577650:DESPR_RS14850
uniprot id: A0A7U3YPD9
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS01690
gene id: 577650:DESPR_RS01690
uniprot id: A0A7U3YJH7
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS16645
gene id: 577650:DESPR_RS16645
uniprot id: A0A7U3YQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS10240
gene id: 577650:DESPR_RS10240
uniprot id: A0A7U4DPL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

577650:DESPR RS00415
gene id: 577650:DESPR_RS00415
uniprot id: A0A7U4DML3
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

577650:DESPR RS11125
gene id: 577650:DESPR_RS11125
uniprot id: A0A7U3YN11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

577650:DESPR RS10875
gene id: 577650:DESPR_RS10875
uniprot id: A0A7U4DPQ8
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

577650:DESPR RS01505
gene id: 577650:DESPR_RS01505
uniprot id: A0A7U3YJP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

577650:DESPR RS08060
gene id: 577650:DESPR_RS08060
uniprot id: A0A7U4DP81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

577650:DESPR RS10170
gene id: 577650:DESPR_RS10170
uniprot id: A0A7U4DPI2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

577650:DESPR RS05640
gene id: 577650:DESPR_RS05640
uniprot id: A0A7U3YKY8
names: Similarity
messages: Belongs to the universal stress protein A family.

577650:DESPR RS16695
gene id: 577650:DESPR_RS16695
uniprot id: A0A7U3YQ09
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

577650:DESPR RS15310
gene id: 577650:DESPR_RS15310
uniprot id: A0A7U3YPJ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS05665
gene id: 577650:DESPR_RS05665
uniprot id: A0A7U3YKY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

577650:DESPR RS01470
gene id: 577650:DESPR_RS01470
uniprot id: A0A7U4DMW2
names: Similarity
messages: Belongs to the peptidase S41A family.

577650:DESPR RS12075
gene id: 577650:DESPR_RS12075
uniprot id: A0A7U4DQ16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

577650:DESPR RS14255
gene id: 577650:DESPR_RS14255
uniprot id: A0A7U3YP65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

577650:DESPR RS14365
gene id: 577650:DESPR_RS14365
uniprot id: A0A7U4DQD3
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS11965
gene id: 577650:DESPR_RS11965
uniprot id: A0A7U3YNA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

577650:DESPR RS13500
gene id: 577650:DESPR_RS13500
uniprot id: A0A7U4DQ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

577650:DESPR RS10730
gene id: 577650:DESPR_RS10730
uniprot id: A0A7U3YMV1
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

577650:DESPR RS11560
gene id: 577650:DESPR_RS11560
uniprot id: A0A7U3YN56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

577650:DESPR RS14545
gene id: 577650:DESPR_RS14545
uniprot id: A0A7U3YP78
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

577650:DESPR RS10565
gene id: 577650:DESPR_RS10565
uniprot id: A0A7U3YMT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

577650:DESPR RS10800
gene id: 577650:DESPR_RS10800
uniprot id: A0A7U4DPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

577650:DESPR RS16585
gene id: 577650:DESPR_RS16585
uniprot id: A0A7U3YQB6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

577650:DESPR RS16600
gene id: 577650:DESPR_RS16600
uniprot id: A0A7U4DQR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

577650:DESPR RS09275
gene id: 577650:DESPR_RS09275
uniprot id: A0A7U4DPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS14130
gene id: 577650:DESPR_RS14130
uniprot id: A0A7U3YP35
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

577650:DESPR RS15805
gene id: 577650:DESPR_RS15805
uniprot id: A0A7U3YPQ7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

577650:DESPR RS17265
gene id: 577650:DESPR_RS17265
uniprot id: A0A7U4DPA0
names: Similarity
messages: Belongs to the peptidase A31 family.

577650:DESPR RS05365
gene id: 577650:DESPR_RS05365
uniprot id: A0A7U3YKW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

577650:DESPR RS18815
gene id: 577650:DESPR_RS18815
uniprot id: A0A7U3YPC8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

577650:DESPR RS08180
gene id: 577650:DESPR_RS08180
uniprot id: A0A7U3YLW4
names: Similarity
messages: Belongs to the thioredoxin family.

577650:DESPR RS03425
gene id: 577650:DESPR_RS03425
uniprot id: A0A7U3YK66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

577650:DESPR RS01150
gene id: 577650:DESPR_RS01150
uniprot id: A0A7U3YJ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

577650:DESPR RS13575
gene id: 577650:DESPR_RS13575
uniprot id: A0A7U3YNW7
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

577650:DESPR RS14920
gene id: 577650:DESPR_RS14920
uniprot id: A0A7U4DQK0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

577650:DESPR RS14180
gene id: 577650:DESPR_RS14180
uniprot id: A0A7U3YP28
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

577650:DESPR RS11165
gene id: 577650:DESPR_RS11165
uniprot id: A0A7U4DPT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

577650:DESPR RS09030
gene id: 577650:DESPR_RS09030
uniprot id: A0A7U3YM84
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

577650:DESPR RS10960
gene id: 577650:DESPR_RS10960
uniprot id: A0A7U4DPN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

577650:DESPR RS14835
gene id: 577650:DESPR_RS14835
uniprot id: A0A7U3YPD4
names: Similarity
messages: Belongs to the thioredoxin family.

577650:DESPR RS11895
gene id: 577650:DESPR_RS11895
uniprot id: A0A7U3YNA2
names: Similarity
messages: Belongs to the peptidase S13 family.

577650:DESPR RS06575
gene id: 577650:DESPR_RS06575
uniprot id: A0A7U3YLL6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS13720
gene id: 577650:DESPR_RS13720
uniprot id: A0A7U3YNY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

577650:DESPR RS00445
gene id: 577650:DESPR_RS00445
uniprot id: A0A7U3YJB7
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

577650:DESPR RS04575
gene id: 577650:DESPR_RS04575
uniprot id: A0A7U3YKJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

577650:DESPR RS08920
gene id: 577650:DESPR_RS08920
uniprot id: A0A7U3YM51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

577650:DESPR RS12885
gene id: 577650:DESPR_RS12885
uniprot id: A0A7U3YNP1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

577650:DESPR RS01865
gene id: 577650:DESPR_RS01865
uniprot id: A0A7U4DN21
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

577650:DESPR RS06975
gene id: 577650:DESPR_RS06975
uniprot id: A0A7U3YLH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

577650:DESPR RS01605
gene id: 577650:DESPR_RS01605
uniprot id: A0A7U4DN29
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

577650:DESPR RS15120
gene id: 577650:DESPR_RS15120
uniprot id: A0A7U4DQH9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

577650:DESPR RS08375
gene id: 577650:DESPR_RS08375
uniprot id: A0A7U4DP64
names: Similarity
messages: Belongs to the UPF0166 family.

577650:DESPR RS08155
gene id: 577650:DESPR_RS08155
uniprot id: A0A7U3YLU6
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

577650:DESPR RS07640
gene id: 577650:DESPR_RS07640
uniprot id: A0A7U4DP23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

577650:DESPR RS03885
gene id: 577650:DESPR_RS03885
uniprot id: A0A7U3YKE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

577650:DESPR RS05900
gene id: 577650:DESPR_RS05900
uniprot id: A0A7U3YL30
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

577650:DESPR RS16310
gene id: 577650:DESPR_RS16310
uniprot id: A0A7U3YPW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

577650:DESPR RS05710
gene id: 577650:DESPR_RS05710
uniprot id: A0A7U4DNP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

577650:DESPR RS11925
gene id: 577650:DESPR_RS11925
uniprot id: A0A7U4DQ07
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

577650:DESPR RS03860
gene id: 577650:DESPR_RS03860
uniprot id: A0A7U3YKA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

577650:DESPR RS07820
gene id: 577650:DESPR_RS07820
uniprot id: A0A7U4DP61
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS08530
gene id: 577650:DESPR_RS08530
uniprot id: A0A7U4DP73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

577650:DESPR RS11980
gene id: 577650:DESPR_RS11980
uniprot id: A0A7U3YNL0
names: Similarity
messages: Belongs to the fabD family.

577650:DESPR RS02195
gene id: 577650:DESPR_RS02195
uniprot id: A0A7U3YJP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

577650:DESPR RS03195
gene id: 577650:DESPR_RS03195
uniprot id: A0A7U3YK22
names: Similarity
messages: Belongs to the HsdR family.

577650:DESPR RS12705
gene id: 577650:DESPR_RS12705
uniprot id: A0A7U4DQ51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

577650:DESPR RS03410
gene id: 577650:DESPR_RS03410
uniprot id: A0A7U3YK85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

577650:DESPR RS04025
gene id: 577650:DESPR_RS04025
uniprot id: A0A7U3YKK9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

577650:DESPR RS07615
gene id: 577650:DESPR_RS07615
uniprot id: A0A7U4DP63
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

577650:DESPR RS16025
gene id: 577650:DESPR_RS16025
uniprot id: A0A7U3YPS9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

577650:DESPR RS07400
gene id: 577650:DESPR_RS07400
uniprot id: A0A7U4DP06
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

577650:DESPR RS07405
gene id: 577650:DESPR_RS07405
uniprot id: A0A7U3YLK9
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

577650:DESPR RS03675
gene id: 577650:DESPR_RS03675
uniprot id: A0A7U3YK88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

577650:DESPR RS07950
gene id: 577650:DESPR_RS07950
uniprot id: A0A7U3YLS9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

577650:DESPR RS13000
gene id: 577650:DESPR_RS13000
uniprot id: A0A7U3YNP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS09620
gene id: 577650:DESPR_RS09620
uniprot id: A0A7U3YMF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

577650:DESPR RS15590
gene id: 577650:DESPR_RS15590
uniprot id: A0A7U4DQJ2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

577650:DESPR RS04315
gene id: 577650:DESPR_RS04315
uniprot id: A0A7U3YKG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS03020
gene id: 577650:DESPR_RS03020
uniprot id: A0A7U4DNA2
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS13710
gene id: 577650:DESPR_RS13710
uniprot id: A0A7U4DQ64
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

577650:DESPR RS03835
gene id: 577650:DESPR_RS03835
uniprot id: A0A7U3YKC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

577650:DESPR RS09390
gene id: 577650:DESPR_RS09390
uniprot id: A0A7U3YMB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

577650:DESPR RS15405
gene id: 577650:DESPR_RS15405
uniprot id: A0A7U3YPJ9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

577650:DESPR RS07220
gene id: 577650:DESPR_RS07220
uniprot id: A0A7U3YLJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

577650:DESPR RS06890
gene id: 577650:DESPR_RS06890
uniprot id: A0A7U4DP15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

577650:DESPR RS16605
gene id: 577650:DESPR_RS16605
uniprot id: A0A7U3YQ02
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

577650:DESPR RS13700
gene id: 577650:DESPR_RS13700
uniprot id: A0A7U4DQ91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

577650:DESPR RS06090
gene id: 577650:DESPR_RS06090
uniprot id: A0A7U3YL54
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

577650:DESPR RS10455
gene id: 577650:DESPR_RS10455
uniprot id: A0A7U4DPN3
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS04600
gene id: 577650:DESPR_RS04600
uniprot id: A0A7U3YKK5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS12365
gene id: 577650:DESPR_RS12365
uniprot id: A0A7U4DQ01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

577650:DESPR RS13455
gene id: 577650:DESPR_RS13455
uniprot id: A0A7U3YP46
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

577650:DESPR RS04765
gene id: 577650:DESPR_RS04765
uniprot id: A0A7U3YKM5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

577650:DESPR RS08980
gene id: 577650:DESPR_RS08980
uniprot id: A0A7U3YM77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

577650:DESPR RS09225
gene id: 577650:DESPR_RS09225
uniprot id: A0A7U3YM98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

577650:DESPR RS02690
gene id: 577650:DESPR_RS02690
uniprot id: A0A7U3YJV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

577650:DESPR RS04930
gene id: 577650:DESPR_RS04930
uniprot id: A0A7U4DNM6
names: Subcellular Location Annotation
messages: Cytoplasm

577650:DESPR RS04535
gene id: 577650:DESPR_RS04535
uniprot id: A0A7U3YKK0
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS12390
gene id: 577650:DESPR_RS12390
uniprot id: A0A7U4DQ33
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

577650:DESPR RS10015
gene id: 577650:DESPR_RS10015
uniprot id: A0A7U3YMM9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

577650:DESPR RS06800
gene id: 577650:DESPR_RS06800
uniprot id: A0A7U3YLP6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

577650:DESPR RS03455
gene id: 577650:DESPR_RS03455
uniprot id: A0A7U3YK53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

577650:DESPR RS13600
gene id: 577650:DESPR_RS13600
uniprot id: A0A7U3YNW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

577650:DESPR RS15850
gene id: 577650:DESPR_RS15850
uniprot id: A0A7U3YPR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

577650:DESPR RS09815
gene id: 577650:DESPR_RS09815
uniprot id: A0A7U3YMI0
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

577650:DESPR RS08200
gene id: 577650:DESPR_RS08200
uniprot id: A0A7U4DP83
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

577650:DESPR RS07975
gene id: 577650:DESPR_RS07975
uniprot id: A0A7U4DP70
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

577650:DESPR RS07650
gene id: 577650:DESPR_RS07650
uniprot id: A0A7U3YLP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

577650:DESPR RS15925
gene id: 577650:DESPR_RS15925
uniprot id: A0A7U3YPR9
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS00180
gene id: 577650:DESPR_RS00180
uniprot id: A0A7U3YIV9
names: Similarity
messages: Belongs to the GSP E family.

577650:DESPR RS09325
gene id: 577650:DESPR_RS09325
uniprot id: A0A7U3YMC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS16690
gene id: 577650:DESPR_RS16690
uniprot id: A0A7U4DQW3
names: Subunit
messages: Heterodimer of a large and a small subunit.

577650:DESPR RS03900
gene id: 577650:DESPR_RS03900
uniprot id: A0A7U3YKC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

577650:DESPR RS03545
gene id: 577650:DESPR_RS03545
uniprot id: A0A7U3YKF0
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

577650:DESPR RS10140
gene id: 577650:DESPR_RS10140
uniprot id: A0A7U3YMN5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

577650:DESPR RS06620
gene id: 577650:DESPR_RS06620
uniprot id: A0A7U3YLB2
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS03295
gene id: 577650:DESPR_RS03295
uniprot id: A0A7U3YK35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

577650:DESPR RS10270
gene id: 577650:DESPR_RS10270
uniprot id: A0A7U3YMP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

577650:DESPR RS08460
gene id: 577650:DESPR_RS08460
uniprot id: A0A7U3YLY6
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

577650:DESPR RS07910
gene id: 577650:DESPR_RS07910
uniprot id: A0A7U4DP71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS08990
gene id: 577650:DESPR_RS08990
uniprot id: A0A7U4DPG1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

577650:DESPR RS04790
gene id: 577650:DESPR_RS04790
uniprot id: A0A7U4DNJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

577650:DESPR RS13855
gene id: 577650:DESPR_RS13855
uniprot id: A0A7U3YP89
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

577650:DESPR RS02620
gene id: 577650:DESPR_RS02620
uniprot id: A0A7U3YJ18
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

577650:DESPR RS16660
gene id: 577650:DESPR_RS16660
uniprot id: A0A7U3YQC4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS06580
gene id: 577650:DESPR_RS06580
uniprot id: A0A7U4DNX9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

577650:DESPR RS05785
gene id: 577650:DESPR_RS05785
uniprot id: A0A7U3YL24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS04405
gene id: 577650:DESPR_RS04405
uniprot id: A0A7U3YKQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

577650:DESPR RS01395
gene id: 577650:DESPR_RS01395
uniprot id: A0A7U4DMV5
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

577650:DESPR RS03875
gene id: 577650:DESPR_RS03875
uniprot id: A0A7U3YKJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

577650:DESPR RS09065
gene id: 577650:DESPR_RS09065
uniprot id: A0A7U4DPG6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

577650:DESPR RS14935
gene id: 577650:DESPR_RS14935
uniprot id: A0A7U3YPG4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

577650:DESPR RS03880
gene id: 577650:DESPR_RS03880
uniprot id: A0A7U4DNE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

577650:DESPR RS06780
gene id: 577650:DESPR_RS06780
uniprot id: A0A7U3YLE6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

577650:DESPR RS08915
gene id: 577650:DESPR_RS08915
uniprot id: A0A7U4DPF4
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

577650:DESPR RS09785
gene id: 577650:DESPR_RS09785
uniprot id: A0A7U3YMS8
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS01765
gene id: 577650:DESPR_RS01765
uniprot id: A0A7U3YJI5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

577650:DESPR RS04110
gene id: 577650:DESPR_RS04110
uniprot id: A0A7U3YKH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

577650:DESPR RS15860
gene id: 577650:DESPR_RS15860
uniprot id: A0A7U4DQJ1
names: Subcellular Location Annotation
messages: Cytoplasm

577650:DESPR RS08700
gene id: 577650:DESPR_RS08700
uniprot id: A0A7U3YM19
names: Subcellular Location Annotation
messages: Periplasm

577650:DESPR RS11600
gene id: 577650:DESPR_RS11600
uniprot id: A0A7U3YN72
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

577650:DESPR RS15795
gene id: 577650:DESPR_RS15795
uniprot id: A0A7U3YPQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

577650:DESPR RS04915
gene id: 577650:DESPR_RS04915
uniprot id: A0A7U3YKP8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

577650:DESPR RS04210
gene id: 577650:DESPR_RS04210
uniprot id: A0A7U3YKF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS13590
gene id: 577650:DESPR_RS13590
uniprot id: A0A7U3YNW3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

577650:DESPR RS17155
gene id: 577650:DESPR_RS17155
uniprot id: A0A7U3YL57
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS08740
gene id: 577650:DESPR_RS08740
uniprot id: A0A7U3YM38
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

577650:DESPR RS12905
gene id: 577650:DESPR_RS12905
uniprot id: A0A7U3YNN1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

577650:DESPR RS04300
gene id: 577650:DESPR_RS04300
uniprot id: A0A7U3YKG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

577650:DESPR RS15090
gene id: 577650:DESPR_RS15090
uniprot id: A0A7U4DQE6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

577650:DESPR RS04425
gene id: 577650:DESPR_RS04425
uniprot id: A0A7U4DNM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

577650:DESPR RS02705
gene id: 577650:DESPR_RS02705
uniprot id: A0A7U3YJV1
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

577650:DESPR RS09205
gene id: 577650:DESPR_RS09205
uniprot id: A0A7U3YMA9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

577650:DESPR RS16020
gene id: 577650:DESPR_RS16020
uniprot id: A0A7U3YPT3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

577650:DESPR RS07495
gene id: 577650:DESPR_RS07495
uniprot id: A0A7U3YLN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

577650:DESPR RS07475
gene id: 577650:DESPR_RS07475
uniprot id: A0A7U3YLN8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

577650:DESPR RS05250
gene id: 577650:DESPR_RS05250
uniprot id: A0A7U4DNL8
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

577650:DESPR RS02530
gene id: 577650:DESPR_RS02530
uniprot id: A0A7U3YJT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

577650:DESPR RS14035
gene id: 577650:DESPR_RS14035
uniprot id: A0A7U3YP23
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

577650:DESPR RS09660
gene id: 577650:DESPR_RS09660
uniprot id: A0A7U3YMF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

577650:DESPR RS06295
gene id: 577650:DESPR_RS06295
uniprot id: A0A7U4DNU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

577650:DESPR RS05805
gene id: 577650:DESPR_RS05805
uniprot id: A0A7U3YL13
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS10470
gene id: 577650:DESPR_RS10470
uniprot id: A0A7U4DPR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS05090
gene id: 577650:DESPR_RS05090
uniprot id: A0A7U4DNN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

577650:DESPR RS14135
gene id: 577650:DESPR_RS14135
uniprot id: A0A7U3YP41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

577650:DESPR RS01905
gene id: 577650:DESPR_RS01905
uniprot id: A0A7U3YJK1
names: Similarity
messages: Belongs to the UPF0758 family.

577650:DESPR RS15815
gene id: 577650:DESPR_RS15815
uniprot id: A0A7U4DQM5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

577650:DESPR RS12385
gene id: 577650:DESPR_RS12385
uniprot id: A0A7U4DPX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS09645
gene id: 577650:DESPR_RS09645
uniprot id: A0A7U3YMH6
names: Similarity
messages: Belongs to the catalase family.

577650:DESPR RS14620
gene id: 577650:DESPR_RS14620
uniprot id: A0A7U3YPB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

577650:DESPR RS06765
gene id: 577650:DESPR_RS06765
uniprot id: A0A7U4DNW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS08345
gene id: 577650:DESPR_RS08345
uniprot id: A0A7U3YLZ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

577650:DESPR RS15990
gene id: 577650:DESPR_RS15990
uniprot id: A0A7U4DQL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

577650:DESPR RS04440
gene id: 577650:DESPR_RS04440
uniprot id: A0A7U3YKI9
names: Similarity
messages: Belongs to the glutamate synthase family.

577650:DESPR RS15695
gene id: 577650:DESPR_RS15695
uniprot id: A0A7U4DQI3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

577650:DESPR RS05675
gene id: 577650:DESPR_RS05675
uniprot id: A0A7U3YL17
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS04480
gene id: 577650:DESPR_RS04480
uniprot id: A0A7U3YKM2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

577650:DESPR RS03740
gene id: 577650:DESPR_RS03740
uniprot id: A0A7U4DNB2
names: Similarity
messages: Belongs to the ribF family.

577650:DESPR RS01790
gene id: 577650:DESPR_RS01790
uniprot id: A0A7U3YJN6
names: Similarity
messages: Belongs to the glutamine synthetase family.

577650:DESPR RS06320
gene id: 577650:DESPR_RS06320
uniprot id: A0A7U3YL71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS07880
gene id: 577650:DESPR_RS07880
uniprot id: A0A7U3YLS6
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS12575
gene id: 577650:DESPR_RS12575
uniprot id: A0A7U3YNJ0
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS14405
gene id: 577650:DESPR_RS14405
uniprot id: A0A7U3YP87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS05380
gene id: 577650:DESPR_RS05380
uniprot id: A0A7U4DNP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS09180
gene id: 577650:DESPR_RS09180
uniprot id: A0A7U3YM99
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Membrane

577650:DESPR RS15885
gene id: 577650:DESPR_RS15885
uniprot id: A0A7U3YQ33
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

577650:DESPR RS03910
gene id: 577650:DESPR_RS03910
uniprot id: A0A7U3YKB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

577650:DESPR RS13405
gene id: 577650:DESPR_RS13405
uniprot id: A0A7U3YNU6
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

577650:DESPR RS10615
gene id: 577650:DESPR_RS10615
uniprot id: A0A7U4DPP0
names: Similarity
messages: Belongs to the histone deacetylase family.

577650:DESPR RS13320
gene id: 577650:DESPR_RS13320
uniprot id: A0A7U4DQ39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

577650:DESPR RS07340
gene id: 577650:DESPR_RS07340
uniprot id: A0A7U3YLM2
names: Similarity
messages: Belongs to the universal stress protein A family.

577650:DESPR RS05855
gene id: 577650:DESPR_RS05855
uniprot id: A0A7U3YL98
names: Subcellular Location Annotation
messages: Cell inner membrane

577650:DESPR RS08085
gene id: 577650:DESPR_RS08085
uniprot id: A0A7U3YLU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

577650:DESPR RS16230
gene id: 577650:DESPR_RS16230
uniprot id: A0A7U4DQT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

577650:DESPR RS02710
gene id: 577650:DESPR_RS02710
uniprot id: A0A7U3YJW3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

577650:DESPR RS13090
gene id: 577650:DESPR_RS13090
uniprot id: A0A7U3YNZ0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

577650:DESPR RS04065
gene id: 577650:DESPR_RS04065
uniprot id: A0A7U4DND1
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

577650:DESPR RS01205
gene id: 577650:DESPR_RS01205
uniprot id: A0A7U3YJB4
names: Subcellular Location Annotation
messages: Membrane

577650:DESPR RS14590
gene id: 577650:DESPR_RS14590
uniprot id: A0A7U3YPJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

577650:DESPR RS15845
gene id: 577650:DESPR_RS15845
uniprot id: A0A7U3YPR4
names: Similarity
messages: Belongs to the SecB family.

577650:DESPR RS19175
gene id: 577650:DESPR_RS19175
uniprot id: A0A7U4DPQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

577650:DESPR RS08875
gene id: 577650:DESPR_RS08875
uniprot id: A0A7U3YM65
names: Similarity
messages: Belongs to the RecJ family.

577650:DESPR RS07105
gene id: 577650:DESPR_RS07105
uniprot id: A0A7U3YLU2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

577650:DESPR RS03890
gene id: 577650:DESPR_RS03890
uniprot id: A0A7U4DND7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

577650:DESPR RS03605
gene id: 577650:DESPR_RS03605
uniprot id: A0A7U3YK78
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

577650:DESPR RS15565
gene id: 577650:DESPR_RS15565
uniprot id: A0A7U3YPM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

577650:DESPR RS03050
gene id: 577650:DESPR_RS03050
uniprot id: A0A7U3YK02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

577650:DESPR RS09650
gene id: 577650:DESPR_RS09650
uniprot id: A0A7U4DPE8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

577650:DESPR RS11325
gene id: 577650:DESPR_RS11325
uniprot id: A0A7U3YNC7
names: Similarity
messages: Belongs to the histone deacetylase family.

577650:DESPR RS09585
gene id: 577650:DESPR_RS09585
uniprot id: A0A7U3YME7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

577650:DESPR RS16485
gene id: 577650:DESPR_RS16485
uniprot id: A0A7U3YPY2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

577650:DESPR RS09360
gene id: 577650:DESPR_RS09360
uniprot id: A0A7U4DPD1
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

577650:DESPR RS17310
gene id: 577650:DESPR_RS17310
uniprot id: A0A7U3YMQ0
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

577650:DESPR RS03265
gene id: 577650:DESPR_RS03265
uniprot id: A0A7U3YK41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

577650:DESPR RS02500
gene id: 577650:DESPR_RS02500
uniprot id: A0A7U4DN53
names: Similarity
messages: Belongs to the sigma-54 factor family.

577650:DESPR RS11115
gene id: 577650:DESPR_RS11115
uniprot id: A0A7U4DPW0
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

577650:DESPR RS07455
gene id: 577650:DESPR_RS07455
uniprot id: A0A7U4DP05
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

577650:DESPR RS08705
gene id: 577650:DESPR_RS08705
uniprot id: A0A7U3YM26
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

577650:DESPR RS15675
gene id: 577650:DESPR_RS15675
uniprot id: A0A7U4DQQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

577650:DESPR RS12540
gene id: 577650:DESPR_RS12540
uniprot id: A0A7U4DPY9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

577650:DESPR RS02515
gene id: 577650:DESPR_RS02515
uniprot id: A0A7U3YJT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

577650:DESPR RS03025
gene id: 577650:DESPR_RS03025
uniprot id: A0A7U3YK29
names: Similarity
messages: Belongs to the HMG-CoA lyase family.