573569:F7308 RS01475
gene id: 573569:F7308_RS01475
uniprot id: F8G8S3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

573569:F7308 RS06085
gene id: 573569:F7308_RS06085
uniprot id: F8G700
names: Similarity
messages: Belongs to the PhoH family.

573569:F7308 RS07050
gene id: 573569:F7308_RS07050
uniprot id: F8G841
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

573569:F7308 RS01755
gene id: 573569:F7308_RS01755
uniprot id: F8G8X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

573569:F7308 RS02990
gene id: 573569:F7308_RS02990
uniprot id: F8GAJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

573569:F7308 RS04770
gene id: 573569:F7308_RS04770
uniprot id: F8GBW9
names: Similarity
messages: Belongs to the glutamate synthase family.

573569:F7308 RS08085
gene id: 573569:F7308_RS08085
uniprot id: F8G958
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

573569:F7308 RS01425
gene id: 573569:F7308_RS01425
uniprot id: F8G8R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS03350
gene id: 573569:F7308_RS03350
uniprot id: F8GAY9
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

573569:F7308 RS04685
gene id: 573569:F7308_RS04685
uniprot id: F8GBV4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

573569:F7308 RS01025
gene id: 573569:F7308_RS01025
uniprot id: F8G8A2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

573569:F7308 RS00365
gene id: 573569:F7308_RS00365
uniprot id: F8G7F7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

573569:F7308 RS01585
gene id: 573569:F7308_RS01585
uniprot id: F8G8U4
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS07815
gene id: 573569:F7308_RS07815
uniprot id: F8G904
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

573569:F7308 RS09055
gene id: 573569:F7308_RS09055
uniprot id: F8GAD9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

573569:F7308 RS08415
gene id: 573569:F7308_RS08415
uniprot id: F8G9K4
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS05920
gene id: 573569:F7308_RS05920
uniprot id: F8G6W7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

573569:F7308 RS08100
gene id: 573569:F7308_RS08100
uniprot id: F8G9E1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

573569:F7308 RS06920
gene id: 573569:F7308_RS06920
uniprot id: F8G813
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

573569:F7308 RS08710
gene id: 573569:F7308_RS08710
uniprot id: F8G9Y8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

573569:F7308 RS00745
gene id: 573569:F7308_RS00745
uniprot id: F8G7W5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

573569:F7308 RS08865
gene id: 573569:F7308_RS08865
uniprot id: F8GA22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

573569:F7308 RS07270
gene id: 573569:F7308_RS07270
uniprot id: F8G885
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573569:F7308 RS05855
gene id: 573569:F7308_RS05855
uniprot id: F8G6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

573569:F7308 RS00120
gene id: 573569:F7308_RS00120
uniprot id: F8G727
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

573569:F7308 RS04580
gene id: 573569:F7308_RS04580
uniprot id: F8GBT1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

573569:F7308 RS07895
gene id: 573569:F7308_RS07895
uniprot id: F8G920
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573569:F7308 RS00880
gene id: 573569:F7308_RS00880
uniprot id: F8G7Z2
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS03130
gene id: 573569:F7308_RS03130
uniprot id: F8GAM2
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

573569:F7308 RS01850
gene id: 573569:F7308_RS01850
uniprot id: F8G978
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

573569:F7308 RS08010
gene id: 573569:F7308_RS08010
uniprot id: F8G943
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS05795
gene id: 573569:F7308_RS05795
uniprot id: F8G6U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

573569:F7308 RS06135
gene id: 573569:F7308_RS06135
uniprot id: F8G744
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS07195
gene id: 573569:F7308_RS07195
uniprot id: F8G870
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

573569:F7308 RS07380
gene id: 573569:F7308_RS07380
uniprot id: F8G8I7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

573569:F7308 RS09695
gene id: 573569:F7308_RS09695
uniprot id: F8GB75
names: Similarity
messages: Belongs to the HypE family.

573569:F7308 RS08265
gene id: 573569:F7308_RS08265
uniprot id: F8G9H4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

573569:F7308 RS08805
gene id: 573569:F7308_RS08805
uniprot id: F8GA10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

573569:F7308 RS02310
gene id: 573569:F7308_RS02310
uniprot id: F8G9Q4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

573569:F7308 RS00990
gene id: 573569:F7308_RS00990
uniprot id: F8G896
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

573569:F7308 RS02150
gene id: 573569:F7308_RS02150
uniprot id: F8G9M0
names: Similarity
messages: Belongs to the UPF0102 family.

573569:F7308 RS02420
gene id: 573569:F7308_RS02420
uniprot id: F8G9R9
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS07670
gene id: 573569:F7308_RS07670
uniprot id: F8G8P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

573569:F7308 RS09005
gene id: 573569:F7308_RS09005
uniprot id: F8GAC9
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

573569:F7308 RS02630
gene id: 573569:F7308_RS02630
uniprot id: F8GA43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573569:F7308 RS01905
gene id: 573569:F7308_RS01905
uniprot id: F8G989
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

573569:F7308 RS00780
gene id: 573569:F7308_RS00780
uniprot id: F8G7X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

573569:F7308 RS03185
gene id: 573569:F7308_RS03185
uniprot id: F8GAM9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS06190
gene id: 573569:F7308_RS06190
uniprot id: F8G754
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573569:F7308 RS07435
gene id: 573569:F7308_RS07435
uniprot id: F8G8J8
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

573569:F7308 RS07095
gene id: 573569:F7308_RS07095
uniprot id: F8G850
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

573569:F7308 RS03795
gene id: 573569:F7308_RS03795
uniprot id: F8GBB8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

573569:F7308 RS03320
gene id: 573569:F7308_RS03320
uniprot id: F8GAQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

573569:F7308 RS00105
gene id: 573569:F7308_RS00105
uniprot id: F8G723
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

573569:F7308 RS04285
gene id: 573569:F7308_RS04285
uniprot id: F8GBL9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

573569:F7308 RS09635
gene id: 573569:F7308_RS09635
uniprot id: F8GAY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

573569:F7308 RS02060
gene id: 573569:F7308_RS02060
uniprot id: F8G9C2
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS03150
gene id: 573569:F7308_RS03150
uniprot id: F8GAM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

573569:F7308 RS01110
gene id: 573569:F7308_RS01110
uniprot id: F8G8B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

573569:F7308 RS09075
gene id: 573569:F7308_RS09075
uniprot id: F8GAE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

573569:F7308 RS02635
gene id: 573569:F7308_RS02635
uniprot id: F8GA44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573569:F7308 RS07960
gene id: 573569:F7308_RS07960
uniprot id: F8G933
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

573569:F7308 RS01525
gene id: 573569:F7308_RS01525
uniprot id: F8G8T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS05940
gene id: 573569:F7308_RS05940
uniprot id: F8G6X1
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

573569:F7308 RS08505
gene id: 573569:F7308_RS08505
uniprot id: F8G9U7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

573569:F7308 RS00190
gene id: 573569:F7308_RS00190
uniprot id: F8G7C2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

573569:F7308 RS01135
gene id: 573569:F7308_RS01135
uniprot id: F8G8C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

573569:F7308 RS03990
gene id: 573569:F7308_RS03990
uniprot id: F8GBF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

573569:F7308 RS03925
gene id: 573569:F7308_RS03925
uniprot id: F8GBE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

573569:F7308 RS02660
gene id: 573569:F7308_RS02660
uniprot id: F8GA49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573569:F7308 RS03700
gene id: 573569:F7308_RS03700
uniprot id: F8GB58
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

573569:F7308 RS01785
gene id: 573569:F7308_RS01785
uniprot id: F8G965
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

573569:F7308 RS01060
gene id: 573569:F7308_RS01060
uniprot id: F8G8A9
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS05420
gene id: 573569:F7308_RS05420
uniprot id: F8GC97
names: Similarity
messages: Belongs to the class A bacterial acid phosphatase family.

573569:F7308 RS08960
gene id: 573569:F7308_RS08960
uniprot id: F8GAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

573569:F7308 RS08655
gene id: 573569:F7308_RS08655
uniprot id: F8G9X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

573569:F7308 RS09240
gene id: 573569:F7308_RS09240
uniprot id: F8GAH7
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS00690
gene id: 573569:F7308_RS00690
uniprot id: F8G7V5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

573569:F7308 RS06615
gene id: 573569:F7308_RS06615
uniprot id: F8G7M0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
messages: In the C-terminal section; belongs to the DHPS family.

573569:F7308 RS02735
gene id: 573569:F7308_RS02735
uniprot id: F8GA63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

573569:F7308 RS04690
gene id: 573569:F7308_RS04690
uniprot id: F8GBV5
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS05905
gene id: 573569:F7308_RS05905
uniprot id: F8G6W4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

573569:F7308 RS05425
gene id: 573569:F7308_RS05425
uniprot id: F8GC98
names: Similarity
messages: Belongs to the DEAD box helicase family.

573569:F7308 RS08190
gene id: 573569:F7308_RS08190
uniprot id: F8G9F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573569:F7308 RS04035
gene id: 573569:F7308_RS04035
uniprot id: F8GBG8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

573569:F7308 RS06195
gene id: 573569:F7308_RS06195
uniprot id: F8G755
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

573569:F7308 RS03920
gene id: 573569:F7308_RS03920
uniprot id: F8GBE5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

573569:F7308 RS06835
gene id: 573569:F7308_RS06835
uniprot id: F8G7R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

573569:F7308 RS05730
gene id: 573569:F7308_RS05730
uniprot id: F8G6S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

573569:F7308 RS05085
gene id: 573569:F7308_RS05085
uniprot id: F8GC28
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS02055
gene id: 573569:F7308_RS02055
uniprot id: F8G9C1
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS00235
gene id: 573569:F7308_RS00235
uniprot id: F8G7D1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.

573569:F7308 RS05300
gene id: 573569:F7308_RS05300
uniprot id: F8GC73
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

573569:F7308 RS08690
gene id: 573569:F7308_RS08690
uniprot id: F8G9Y4
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS00715
gene id: 573569:F7308_RS00715
uniprot id: F8G7V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573569:F7308 RS05765
gene id: 573569:F7308_RS05765
uniprot id: F8G6T5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

573569:F7308 RS03530
gene id: 573569:F7308_RS03530
uniprot id: F8GB24
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS04835
gene id: 573569:F7308_RS04835
uniprot id: F8GBY2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

573569:F7308 RS07790
gene id: 573569:F7308_RS07790
uniprot id: F8G8Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

573569:F7308 RS04700
gene id: 573569:F7308_RS04700
uniprot id: F8GBV7
names: Similarity
messages: Belongs to the SufE family.

573569:F7308 RS08255
gene id: 573569:F7308_RS08255
uniprot id: F8G9H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

573569:F7308 RS03360
gene id: 573569:F7308_RS03360
uniprot id: F8GAZ1
names: Similarity
messages: Belongs to the UPF0246 family.

573569:F7308 RS09285
gene id: 573569:F7308_RS09285
uniprot id: F8GAR3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

573569:F7308 RS04385
gene id: 573569:F7308_RS04385
uniprot id: F8GBP1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

573569:F7308 RS01965
gene id: 573569:F7308_RS01965
uniprot id: F8G9A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

573569:F7308 RS04930
gene id: 573569:F7308_RS04930
uniprot id: F8GC01
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

573569:F7308 RS04875
gene id: 573569:F7308_RS04875
uniprot id: F8GBZ0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

573569:F7308 RS09750
gene id: 573569:F7308_RS09750
uniprot id: F8GB87
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

573569:F7308 RS06365
gene id: 573569:F7308_RS06365
uniprot id: F8G789
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

573569:F7308 RS02960
gene id: 573569:F7308_RS02960
uniprot id: F8GAI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

573569:F7308 RS01760
gene id: 573569:F7308_RS01760
uniprot id: F8G8X9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

573569:F7308 RS00230
gene id: 573569:F7308_RS00230
uniprot id: F8G7D0
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

573569:F7308 RS08125
gene id: 573569:F7308_RS08125
uniprot id: F8G9E6
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS05525
gene id: 573569:F7308_RS05525
uniprot id: F8GCB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

573569:F7308 RS03645
gene id: 573569:F7308_RS03645
uniprot id: F8GB47
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS07245
gene id: 573569:F7308_RS07245
uniprot id: F8G880
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

573569:F7308 RS06740
gene id: 573569:F7308_RS06740
uniprot id: F8G7P6
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

573569:F7308 RS05490
gene id: 573569:F7308_RS05490
uniprot id: F8GCB2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

573569:F7308 RS08770
gene id: 573569:F7308_RS08770
uniprot id: F8GA01
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

573569:F7308 RS04970
gene id: 573569:F7308_RS04970
uniprot id: F8GC09
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS06050
gene id: 573569:F7308_RS06050
uniprot id: F8G6Z3
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

573569:F7308 RS06045
gene id: 573569:F7308_RS06045
uniprot id: F8G6Z2
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

573569:F7308 RS07110
gene id: 573569:F7308_RS07110
uniprot id: F8G853
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

573569:F7308 RS07795
gene id: 573569:F7308_RS07795
uniprot id: F8G900
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS07890
gene id: 573569:F7308_RS07890
uniprot id: F8G919
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

573569:F7308 RS06215
gene id: 573569:F7308_RS06215
uniprot id: F8G759
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

573569:F7308 RS02805
gene id: 573569:F7308_RS02805
uniprot id: F8GA77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

573569:F7308 RS08310
gene id: 573569:F7308_RS08310
uniprot id: F8G9I4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

573569:F7308 RS03465
gene id: 573569:F7308_RS03465
uniprot id: F8GB12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

573569:F7308 RS02090
gene id: 573569:F7308_RS02090
uniprot id: F8G9C8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573569:F7308 RS00625
gene id: 573569:F7308_RS00625
uniprot id: F8G7U1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

573569:F7308 RS07755
gene id: 573569:F7308_RS07755
uniprot id: F8G8Z1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

573569:F7308 RS06495
gene id: 573569:F7308_RS06495
uniprot id: F8G7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS00565
gene id: 573569:F7308_RS00565
uniprot id: F8G7J7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

573569:F7308 RS01815
gene id: 573569:F7308_RS01815
uniprot id: F8G971
names: Similarity
messages: Belongs to the ArsC family.

573569:F7308 RS00450
gene id: 573569:F7308_RS00450
uniprot id: F8G7H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

573569:F7308 RS08585
gene id: 573569:F7308_RS08585
uniprot id: F8G9W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

573569:F7308 RS00485
gene id: 573569:F7308_RS00485
uniprot id: F8G7I1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

573569:F7308 RS05720
gene id: 573569:F7308_RS05720
uniprot id: F8G6S6
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS08855
gene id: 573569:F7308_RS08855
uniprot id: F8GA20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

573569:F7308 RS08130
gene id: 573569:F7308_RS08130
uniprot id: F8G9E7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

573569:F7308 RS07695
gene id: 573569:F7308_RS07695
uniprot id: F8G8Y0
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS05885
gene id: 573569:F7308_RS05885
uniprot id: F8G6W0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

573569:F7308 RS02650
gene id: 573569:F7308_RS02650
uniprot id: F8GA47
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

573569:F7308 RS05650
gene id: 573569:F7308_RS05650
uniprot id: F8GCD7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

573569:F7308 RS04915
gene id: 573569:F7308_RS04915
uniprot id: F8GBZ8
names: Similarity
messages: Belongs to the fabD family.

573569:F7308 RS04950
gene id: 573569:F7308_RS04950
uniprot id: F8GC05
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573569:F7308 RS02345
gene id: 573569:F7308_RS02345
uniprot id: F8G9R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

573569:F7308 RS01940
gene id: 573569:F7308_RS01940
uniprot id: F8G997
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS06420
gene id: 573569:F7308_RS06420
uniprot id: F8G7A0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

573569:F7308 RS03260
gene id: 573569:F7308_RS03260
uniprot id: F8GAP4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

573569:F7308 RS00540
gene id: 573569:F7308_RS00540
uniprot id: F8G7J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

573569:F7308 RS08095
gene id: 573569:F7308_RS08095
uniprot id: F8G960
names: Similarity
messages: Belongs to the HesB/IscA family.

573569:F7308 RS08935
gene id: 573569:F7308_RS08935
uniprot id: F8GAB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

573569:F7308 RS03115
gene id: 573569:F7308_RS03115
uniprot id: F8GAL9
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS03035
gene id: 573569:F7308_RS03035
uniprot id: F8GAK3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573569:F7308 RS01855
gene id: 573569:F7308_RS01855
uniprot id: F8G979
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

573569:F7308 RS05915
gene id: 573569:F7308_RS05915
uniprot id: F8G6W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

573569:F7308 RS08620
gene id: 573569:F7308_RS08620
uniprot id: F8G9X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

573569:F7308 RS03660
gene id: 573569:F7308_RS03660
uniprot id: F8GB50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

573569:F7308 RS03255
gene id: 573569:F7308_RS03255
uniprot id: F8GAP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

573569:F7308 RS00010
gene id: 573569:F7308_RS00010
uniprot id: F8G703
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

573569:F7308 RS07910
gene id: 573569:F7308_RS07910
uniprot id: F8G923
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

573569:F7308 RS06280
gene id: 573569:F7308_RS06280
uniprot id: F8G772
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

573569:F7308 RS00215
gene id: 573569:F7308_RS00215
uniprot id: F8G7C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

573569:F7308 RS03615
gene id: 573569:F7308_RS03615
uniprot id: F8GB41
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

573569:F7308 RS01595
gene id: 573569:F7308_RS01595
uniprot id: F8G8U6
names: Similarity
messages: Belongs to the FBPase class 2 family.

573569:F7308 RS06030
gene id: 573569:F7308_RS06030
uniprot id: F8G6Y9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

573569:F7308 RS03195
gene id: 573569:F7308_RS03195
uniprot id: F8GAN1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

573569:F7308 RS06305
gene id: 573569:F7308_RS06305
uniprot id: F8G777
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS06600
gene id: 573569:F7308_RS06600
uniprot id: F8G7L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

573569:F7308 RS09010
gene id: 573569:F7308_RS09010
uniprot id: F8GAD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.

573569:F7308 RS05430
gene id: 573569:F7308_RS05430
uniprot id: F8GC99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

573569:F7308 RS02655
gene id: 573569:F7308_RS02655
uniprot id: F8GA48
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

573569:F7308 RS09355
gene id: 573569:F7308_RS09355
uniprot id: F8GAS3
names: Similarity
messages: Belongs to the DapB family.

573569:F7308 RS04005
gene id: 573569:F7308_RS04005
uniprot id: F8GBG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

573569:F7308 RS07905
gene id: 573569:F7308_RS07905
uniprot id: F8G922
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

573569:F7308 RS07130
gene id: 573569:F7308_RS07130
uniprot id: F8G857
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

573569:F7308 RS07240
gene id: 573569:F7308_RS07240
uniprot id: F8G879
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

573569:F7308 RS02640
gene id: 573569:F7308_RS02640
uniprot id: F8GA45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573569:F7308 RS00545
gene id: 573569:F7308_RS00545
uniprot id: F8G7J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

573569:F7308 RS05410
gene id: 573569:F7308_RS05410
uniprot id: F8GC95
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

573569:F7308 RS03570
gene id: 573569:F7308_RS03570
uniprot id: F8GB32
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

573569:F7308 RS01170
gene id: 573569:F7308_RS01170
uniprot id: F8G8D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

573569:F7308 RS06475
gene id: 573569:F7308_RS06475
uniprot id: F8G7B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

573569:F7308 RS09690
gene id: 573569:F7308_RS09690
uniprot id: F8GB74
names: Similarity
messages: Belongs to the HypD family.

573569:F7308 RS02720
gene id: 573569:F7308_RS02720
uniprot id: F8GA60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

573569:F7308 RS09115
gene id: 573569:F7308_RS09115
uniprot id: F8GAF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

573569:F7308 RS09615
gene id: 573569:F7308_RS09615
uniprot id: F8GAY1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

573569:F7308 RS04605
gene id: 573569:F7308_RS04605
uniprot id: F8GBT6
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS03730
gene id: 573569:F7308_RS03730
uniprot id: F8GB63
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

573569:F7308 RS05095
gene id: 573569:F7308_RS05095
uniprot id: F8GC31
names: Similarity
messages: Belongs to the peptidase C59 family.

573569:F7308 RS05400
gene id: 573569:F7308_RS05400
uniprot id: F8GC93
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

573569:F7308 RS05140
gene id: 573569:F7308_RS05140
uniprot id: F8GC40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

573569:F7308 RS01190
gene id: 573569:F7308_RS01190
uniprot id: F8G8D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

573569:F7308 RS07970
gene id: 573569:F7308_RS07970
uniprot id: F8G935
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

573569:F7308 RS03975
gene id: 573569:F7308_RS03975
uniprot id: F8GBF7
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

573569:F7308 RS08565
gene id: 573569:F7308_RS08565
uniprot id: F8G9W0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

573569:F7308 RS09265
gene id: 573569:F7308_RS09265
uniprot id: F8GAI2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

573569:F7308 RS04175
gene id: 573569:F7308_RS04175
uniprot id: F8GBJ6
names: Similarity
messages: Belongs to the ArsC family.

573569:F7308 RS06265
gene id: 573569:F7308_RS06265
uniprot id: F8G769
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

573569:F7308 RS07235
gene id: 573569:F7308_RS07235
uniprot id: F8G878
names: Similarity
messages: Belongs to the peptidase M17 family.

573569:F7308 RS02860
gene id: 573569:F7308_RS02860
uniprot id: F8GA88
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

573569:F7308 RS01120
gene id: 573569:F7308_RS01120
uniprot id: F8G8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

573569:F7308 RS04195
gene id: 573569:F7308_RS04195
uniprot id: F8GBK1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

573569:F7308 RS02200
gene id: 573569:F7308_RS02200
uniprot id: F8G9N0
names: Similarity
messages: Belongs to the ParB family.

573569:F7308 RS04165
gene id: 573569:F7308_RS04165
uniprot id: F8GBJ4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

573569:F7308 RS03555
gene id: 573569:F7308_RS03555
uniprot id: F8GB29
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS08580
gene id: 573569:F7308_RS08580
uniprot id: F8G9W3
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS09880
gene id: 573569:F7308_RS09880
uniprot id: F8G7X1
names: Similarity
messages: Belongs to the class A bacterial acid phosphatase family.

573569:F7308 RS05220
gene id: 573569:F7308_RS05220
uniprot id: F8GC57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

573569:F7308 RS02615
gene id: 573569:F7308_RS02615
uniprot id: F8GA39
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

573569:F7308 RS02000
gene id: 573569:F7308_RS02000
uniprot id: F8G9A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

573569:F7308 RS08925
gene id: 573569:F7308_RS08925
uniprot id: F8GAB3
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

573569:F7308 RS01375
gene id: 573569:F7308_RS01375
uniprot id: F8G8Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

573569:F7308 RS04900
gene id: 573569:F7308_RS04900
uniprot id: F8GBZ5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

573569:F7308 RS07760
gene id: 573569:F7308_RS07760
uniprot id: F8G8Z2
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS08570
gene id: 573569:F7308_RS08570
uniprot id: F8G9W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

573569:F7308 RS02275
gene id: 573569:F7308_RS02275
uniprot id: F8G9P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

573569:F7308 RS01275
gene id: 573569:F7308_RS01275
uniprot id: F8G8F1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

573569:F7308 RS09790
gene id: 573569:F7308_RS09790
uniprot id: F8GB95
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS00820
gene id: 573569:F7308_RS00820
uniprot id: F8G7Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

573569:F7308 RS01570
gene id: 573569:F7308_RS01570
uniprot id: F8G8U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

573569:F7308 RS02645
gene id: 573569:F7308_RS02645
uniprot id: F8GA46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573569:F7308 RS07920
gene id: 573569:F7308_RS07920
uniprot id: F8G925
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

573569:F7308 RS03125
gene id: 573569:F7308_RS03125
uniprot id: F8GAM1
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS03605
gene id: 573569:F7308_RS03605
uniprot id: F8GB39
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS01235
gene id: 573569:F7308_RS01235
uniprot id: F8G8E3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

573569:F7308 RS06435
gene id: 573569:F7308_RS06435
uniprot id: F8G7A3
names: Similarity
messages: Belongs to the catalase family.

573569:F7308 RS05975
gene id: 573569:F7308_RS05975
uniprot id: F8G6X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

573569:F7308 RS08180
gene id: 573569:F7308_RS08180
uniprot id: F8G9F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

573569:F7308 RS02695
gene id: 573569:F7308_RS02695
uniprot id: F8GA56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573569:F7308 RS08735
gene id: 573569:F7308_RS08735
uniprot id: F8G9Z3
names: Similarity
messages: Belongs to the Gfa family.

573569:F7308 RS01890
gene id: 573569:F7308_RS01890
uniprot id: F8G986
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

573569:F7308 RS08025
gene id: 573569:F7308_RS08025
uniprot id: F8G946
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS08050
gene id: 573569:F7308_RS08050
uniprot id: F8G951
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

573569:F7308 RS01500
gene id: 573569:F7308_RS01500
uniprot id: F8G8S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

573569:F7308 RS03315
gene id: 573569:F7308_RS03315
uniprot id: F8GAQ5
names: Similarity
messages: Belongs to the UPF0597 family.

573569:F7308 RS08875
gene id: 573569:F7308_RS08875
uniprot id: F8GA24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

573569:F7308 RS07665
gene id: 573569:F7308_RS07665
uniprot id: F8G8P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

573569:F7308 RS03340
gene id: 573569:F7308_RS03340
uniprot id: F8GAR0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

573569:F7308 RS07660
gene id: 573569:F7308_RS07660
uniprot id: F8G8P3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

573569:F7308 RS01350
gene id: 573569:F7308_RS01350
uniprot id: F8G8G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

573569:F7308 RS06425
gene id: 573569:F7308_RS06425
uniprot id: F8G7A1
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

573569:F7308 RS00720
gene id: 573569:F7308_RS00720
uniprot id: F8G7W0
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS00240
gene id: 573569:F7308_RS00240
uniprot id: F8G7D2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

573569:F7308 RS05250
gene id: 573569:F7308_RS05250
uniprot id: F8GC63
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS06005
gene id: 573569:F7308_RS06005
uniprot id: F8G6Y4
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS08065
gene id: 573569:F7308_RS08065
uniprot id: F8G954
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

573569:F7308 RS03140
gene id: 573569:F7308_RS03140
uniprot id: F8GAM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

573569:F7308 RS04010
gene id: 573569:F7308_RS04010
uniprot id: F8GBG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

573569:F7308 RS09090
gene id: 573569:F7308_RS09090
uniprot id: F8GAE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

573569:F7308 RS07775
gene id: 573569:F7308_RS07775
uniprot id: F8G8Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

573569:F7308 RS09000
gene id: 573569:F7308_RS09000
uniprot id: F8GAC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS07285
gene id: 573569:F7308_RS07285
uniprot id: F8G888
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573569:F7308 RS01655
gene id: 573569:F7308_RS01655
uniprot id: F8G8V9
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

573569:F7308 RS08725
gene id: 573569:F7308_RS08725
uniprot id: F8G9Z1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

573569:F7308 RS04655
gene id: 573569:F7308_RS04655
uniprot id: F8GBU8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

573569:F7308 RS08525
gene id: 573569:F7308_RS08525
uniprot id: F8G9V1
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS09270
gene id: 573569:F7308_RS09270
uniprot id: F8GAI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

573569:F7308 RS01825
gene id: 573569:F7308_RS01825
uniprot id: F8G973
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

573569:F7308 RS06080
gene id: 573569:F7308_RS06080
uniprot id: F8G6Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

573569:F7308 RS06325
gene id: 573569:F7308_RS06325
uniprot id: F8G781
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

573569:F7308 RS08775
gene id: 573569:F7308_RS08775
uniprot id: F8GA02
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS00620
gene id: 573569:F7308_RS00620
uniprot id: F8G7U0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

573569:F7308 RS09705
gene id: 573569:F7308_RS09705
uniprot id: F8GB77
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

573569:F7308 RS04560
gene id: 573569:F7308_RS04560
uniprot id: F8GBS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS00505
gene id: 573569:F7308_RS00505
uniprot id: F8G7I5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

573569:F7308 RS04515
gene id: 573569:F7308_RS04515
uniprot id: F8GBR7
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS05365
gene id: 573569:F7308_RS05365
uniprot id: F8GC86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

573569:F7308 RS02130
gene id: 573569:F7308_RS02130
uniprot id: F8G9D7
names: Similarity
messages: Belongs to the GARS family.
messages: Belongs to the SAICAR synthetase family.

573569:F7308 RS03230
gene id: 573569:F7308_RS03230
uniprot id: F8GAN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

573569:F7308 RS05415
gene id: 573569:F7308_RS05415
uniprot id: F8GC96
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

573569:F7308 RS06245
gene id: 573569:F7308_RS06245
uniprot id: F8G765
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

573569:F7308 RS00985
gene id: 573569:F7308_RS00985
uniprot id: F8G895
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

573569:F7308 RS06490
gene id: 573569:F7308_RS06490
uniprot id: F8G7B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

573569:F7308 RS02410
gene id: 573569:F7308_RS02410
uniprot id: F8G9R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

573569:F7308 RS05935
gene id: 573569:F7308_RS05935
uniprot id: F8G6X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

573569:F7308 RS07850
gene id: 573569:F7308_RS07850
uniprot id: F8G911
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS08910
gene id: 573569:F7308_RS08910
uniprot id: F8GAB0
names: Similarity
messages: Belongs to the peptidase S49 family.

573569:F7308 RS02820
gene id: 573569:F7308_RS02820
uniprot id: F8GA80
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

573569:F7308 RS01165
gene id: 573569:F7308_RS01165
uniprot id: F8G8C9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

573569:F7308 RS02850
gene id: 573569:F7308_RS02850
uniprot id: F8GA86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS03750
gene id: 573569:F7308_RS03750
uniprot id: F8GBA8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

573569:F7308 RS01750
gene id: 573569:F7308_RS01750
uniprot id: F8G8X7
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

573569:F7308 RS00260
gene id: 573569:F7308_RS00260
uniprot id: F8G7D5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

573569:F7308 RS00900
gene id: 573569:F7308_RS00900
uniprot id: F8G7Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

573569:F7308 RS06895
gene id: 573569:F7308_RS06895
uniprot id: F8G7S7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

573569:F7308 RS02190
gene id: 573569:F7308_RS02190
uniprot id: F8G9M8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

573569:F7308 RS06455
gene id: 573569:F7308_RS06455
uniprot id: F8G7A7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS02540
gene id: 573569:F7308_RS02540
uniprot id: F8G9U4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

573569:F7308 RS05360
gene id: 573569:F7308_RS05360
uniprot id: F8GC85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

573569:F7308 RS01930
gene id: 573569:F7308_RS01930
uniprot id: F8G995
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS06530
gene id: 573569:F7308_RS06530
uniprot id: F8G7K3
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS06035
gene id: 573569:F7308_RS06035
uniprot id: F8G6Z0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

573569:F7308 RS01345
gene id: 573569:F7308_RS01345
uniprot id: F8G8G6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS01105
gene id: 573569:F7308_RS01105
uniprot id: F8G8B7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS07555
gene id: 573569:F7308_RS07555
uniprot id: F8G8M2
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS02155
gene id: 573569:F7308_RS02155
uniprot id: F8G9M1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

573569:F7308 RS08890
gene id: 573569:F7308_RS08890
uniprot id: F8GAA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

573569:F7308 RS01320
gene id: 573569:F7308_RS01320
uniprot id: F8G8G0
names: Similarity
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

573569:F7308 RS02770
gene id: 573569:F7308_RS02770
uniprot id: F8GA70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

573569:F7308 RS09060
gene id: 573569:F7308_RS09060
uniprot id: F8GAE0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

573569:F7308 RS02440
gene id: 573569:F7308_RS02440
uniprot id: F8G9S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

573569:F7308 RS07415
gene id: 573569:F7308_RS07415
uniprot id: F8G8J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

573569:F7308 RS05335
gene id: 573569:F7308_RS05335
uniprot id: F8GC80
names: Similarity
messages: Belongs to the peptidase C59 family.

573569:F7308 RS07580
gene id: 573569:F7308_RS07580
uniprot id: F8G8M6
names: Subcellular Location Annotation
messages: Cytoplasm

573569:F7308 RS05370
gene id: 573569:F7308_RS05370
uniprot id: F8GC87
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

573569:F7308 RS07585
gene id: 573569:F7308_RS07585
uniprot id: F8G8M7
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

573569:F7308 RS04030
gene id: 573569:F7308_RS04030
uniprot id: F8GBG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

573569:F7308 RS07780
gene id: 573569:F7308_RS07780
uniprot id: F8G8Z7
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

573569:F7308 RS02670
gene id: 573569:F7308_RS02670
uniprot id: F8GA51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573569:F7308 RS06690
gene id: 573569:F7308_RS06690
uniprot id: F8G7N5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

573569:F7308 RS09730
gene id: 573569:F7308_RS09730
uniprot id: F8GB82
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

573569:F7308 RS07935
gene id: 573569:F7308_RS07935
uniprot id: F8G928
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

573569:F7308 RS06970
gene id: 573569:F7308_RS06970
uniprot id: F8G823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

573569:F7308 RS06105
gene id: 573569:F7308_RS06105
uniprot id: F8G738
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

573569:F7308 RS03205
gene id: 573569:F7308_RS03205
uniprot id: F8GAN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

573569:F7308 RS09805
gene id: 573569:F7308_RS09805
uniprot id: F8GB98
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.

573569:F7308 RS05775
gene id: 573569:F7308_RS05775
uniprot id: F8G6T7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

573569:F7308 RS08515
gene id: 573569:F7308_RS08515
uniprot id: F8G9U9
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS06565
gene id: 573569:F7308_RS06565
uniprot id: F8G7L0
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS05960
gene id: 573569:F7308_RS05960
uniprot id: F8G6X5
names: Similarity
messages: Belongs to the MlaA family.

573569:F7308 RS02955
gene id: 573569:F7308_RS02955
uniprot id: F8GAI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

573569:F7308 RS07940
gene id: 573569:F7308_RS07940
uniprot id: F8G929
names: Similarity
messages: Belongs to the asparaginase 1 family.

573569:F7308 RS06520
gene id: 573569:F7308_RS06520
uniprot id: F8G7K1
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

573569:F7308 RS01705
gene id: 573569:F7308_RS01705
uniprot id: F8G8W8
names: Similarity
messages: Belongs to the MlaA family.

573569:F7308 RS06145
gene id: 573569:F7308_RS06145
uniprot id: F8G745
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

573569:F7308 RS02730
gene id: 573569:F7308_RS02730
uniprot id: F8GA62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

573569:F7308 RS06515
gene id: 573569:F7308_RS06515
uniprot id: F8G7K0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

573569:F7308 RS01270
gene id: 573569:F7308_RS01270
uniprot id: F8G8F0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

573569:F7308 RS06675
gene id: 573569:F7308_RS06675
uniprot id: F8G7N2
names: Similarity
messages: Belongs to the DEAD box helicase family.

573569:F7308 RS04920
gene id: 573569:F7308_RS04920
uniprot id: F8GBZ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

573569:F7308 RS02995
gene id: 573569:F7308_RS02995
uniprot id: F8GAJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS08550
gene id: 573569:F7308_RS08550
uniprot id: F8G9V7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

573569:F7308 RS03385
gene id: 573569:F7308_RS03385
uniprot id: F8GAZ6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

573569:F7308 RS08305
gene id: 573569:F7308_RS08305
uniprot id: F8G9I3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

573569:F7308 RS07085
gene id: 573569:F7308_RS07085
uniprot id: F8G848
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

573569:F7308 RS08230
gene id: 573569:F7308_RS08230
uniprot id: F8G9G7
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

573569:F7308 RS06500
gene id: 573569:F7308_RS06500
uniprot id: F8G7B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS01215
gene id: 573569:F7308_RS01215
uniprot id: F8G8D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

573569:F7308 RS00095
gene id: 573569:F7308_RS00095
uniprot id: F8G721
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

573569:F7308 RS01195
gene id: 573569:F7308_RS01195
uniprot id: F8G8D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

573569:F7308 RS04000
gene id: 573569:F7308_RS04000
uniprot id: F8GBG1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

573569:F7308 RS01835
gene id: 573569:F7308_RS01835
uniprot id: F8G975
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS08985
gene id: 573569:F7308_RS08985
uniprot id: F8GAC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

573569:F7308 RS08275
gene id: 573569:F7308_RS08275
uniprot id: F8G9H6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

573569:F7308 RS09395
gene id: 573569:F7308_RS09395
uniprot id: F8GAT2
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS08235
gene id: 573569:F7308_RS08235
uniprot id: F8G9G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

573569:F7308 RS09040
gene id: 573569:F7308_RS09040
uniprot id: F8GAD6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

573569:F7308 RS03300
gene id: 573569:F7308_RS03300
uniprot id: F8GAQ2
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

573569:F7308 RS04180
gene id: 573569:F7308_RS04180
uniprot id: F8GBJ7
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

573569:F7308 RS02610
gene id: 573569:F7308_RS02610
uniprot id: F8GA38
names: Similarity
messages: Belongs to the group II decarboxylase family.

573569:F7308 RS03380
gene id: 573569:F7308_RS03380
uniprot id: F8GAZ5
names: Subunit
messages: Monomer.

573569:F7308 RS06790
gene id: 573569:F7308_RS06790
uniprot id: F8G7Q6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

573569:F7308 RS05390
gene id: 573569:F7308_RS05390
uniprot id: F8GC91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS04350
gene id: 573569:F7308_RS04350
uniprot id: F8GBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS02755
gene id: 573569:F7308_RS02755
uniprot id: F8GA67
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

573569:F7308 RS02760
gene id: 573569:F7308_RS02760
uniprot id: F8GA68
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS06465
gene id: 573569:F7308_RS06465
uniprot id: F8G7A9
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

573569:F7308 RS02025
gene id: 573569:F7308_RS02025
uniprot id: F8G9B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

573569:F7308 RS07100
gene id: 573569:F7308_RS07100
uniprot id: F8G851
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

573569:F7308 RS01670
gene id: 573569:F7308_RS01670
uniprot id: F8G8W2
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS07080
gene id: 573569:F7308_RS07080
uniprot id: F8G847
names: Similarity
messages: Belongs to the UPF0250 family.

573569:F7308 RS09065
gene id: 573569:F7308_RS09065
uniprot id: F8GAE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

573569:F7308 RS03960
gene id: 573569:F7308_RS03960
uniprot id: F8GBF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

573569:F7308 RS08475
gene id: 573569:F7308_RS08475
uniprot id: F8G9L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS03215
gene id: 573569:F7308_RS03215
uniprot id: F8GAN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

573569:F7308 RS05210
gene id: 573569:F7308_RS05210
uniprot id: F8GC55
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

573569:F7308 RS05700
gene id: 573569:F7308_RS05700
uniprot id: F8G6S1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

573569:F7308 RS03135
gene id: 573569:F7308_RS03135
uniprot id: F8GAM3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

573569:F7308 RS08675
gene id: 573569:F7308_RS08675
uniprot id: F8G9Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

573569:F7308 RS02340
gene id: 573569:F7308_RS02340
uniprot id: F8G9R0
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS05280
gene id: 573569:F7308_RS05280
uniprot id: F8GC69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

573569:F7308 RS01975
gene id: 573569:F7308_RS01975
uniprot id: F8G9A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

573569:F7308 RS04190
gene id: 573569:F7308_RS04190
uniprot id: F8GBK0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

573569:F7308 RS08285
gene id: 573569:F7308_RS08285
uniprot id: F8G9H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

573569:F7308 RS08245
gene id: 573569:F7308_RS08245
uniprot id: F8G9H0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

573569:F7308 RS00420
gene id: 573569:F7308_RS00420
uniprot id: F8G7G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

573569:F7308 RS06940
gene id: 573569:F7308_RS06940
uniprot id: F8G817
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

573569:F7308 RS03335
gene id: 573569:F7308_RS03335
uniprot id: F8GAQ9
names: Similarity
messages: Belongs to the YfgM family.

573569:F7308 RS03995
gene id: 573569:F7308_RS03995
uniprot id: F8GBG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

573569:F7308 RS07370
gene id: 573569:F7308_RS07370
uniprot id: F8G8I5
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

573569:F7308 RS06825
gene id: 573569:F7308_RS06825
uniprot id: F8G7R3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

573569:F7308 RS02680
gene id: 573569:F7308_RS02680
uniprot id: F8GA53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573569:F7308 RS06710
gene id: 573569:F7308_RS06710
uniprot id: F8G7N9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

573569:F7308 RS06670
gene id: 573569:F7308_RS06670
uniprot id: F8G7N1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

573569:F7308 RS02815
gene id: 573569:F7308_RS02815
uniprot id: F8GA79
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

573569:F7308 RS02785
gene id: 573569:F7308_RS02785
uniprot id: F8GA73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

573569:F7308 RS02685
gene id: 573569:F7308_RS02685
uniprot id: F8GA54
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS00255
gene id: 573569:F7308_RS00255
uniprot id: F8G7D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

573569:F7308 RS02675
gene id: 573569:F7308_RS02675
uniprot id: F8GA52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

573569:F7308 RS04525
gene id: 573569:F7308_RS04525
uniprot id: F8GBS0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

573569:F7308 RS04940
gene id: 573569:F7308_RS04940
uniprot id: F8GC03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

573569:F7308 RS04600
gene id: 573569:F7308_RS04600
uniprot id: F8GBT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

573569:F7308 RS04155
gene id: 573569:F7308_RS04155
uniprot id: F8GBJ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

573569:F7308 RS07550
gene id: 573569:F7308_RS07550
uniprot id: F8G8M1
names: Similarity
messages: Belongs to the UDPGP type 2 family.

573569:F7308 RS02455
gene id: 573569:F7308_RS02455
uniprot id: F8G9S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

573569:F7308 RS06870
gene id: 573569:F7308_RS06870
uniprot id: F8G7S2
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS02515
gene id: 573569:F7308_RS02515
uniprot id: F8G9T9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

573569:F7308 RS05655
gene id: 573569:F7308_RS05655
uniprot id: F8GCD8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

573569:F7308 RS00550
gene id: 573569:F7308_RS00550
uniprot id: F8G7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

573569:F7308 RS08880
gene id: 573569:F7308_RS08880
uniprot id: F8GAA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

573569:F7308 RS08070
gene id: 573569:F7308_RS08070
uniprot id: F8G955
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

573569:F7308 RS03945
gene id: 573569:F7308_RS03945
uniprot id: F8GBF1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS03500
gene id: 573569:F7308_RS03500
uniprot id: F8GB18
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS00800
gene id: 573569:F7308_RS00800
uniprot id: F8G7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS03050
gene id: 573569:F7308_RS03050
uniprot id: F8GAK6
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS07165
gene id: 573569:F7308_RS07165
uniprot id: F8G864
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

573569:F7308 RS07845
gene id: 573569:F7308_RS07845
uniprot id: F8G910
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

573569:F7308 RS00305
gene id: 573569:F7308_RS00305
uniprot id: F8G7E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

573569:F7308 RS01745
gene id: 573569:F7308_RS01745
uniprot id: F8G8X6
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

573569:F7308 RS09150
gene id: 573569:F7308_RS09150
uniprot id: F8GAF7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

573569:F7308 RS05520
gene id: 573569:F7308_RS05520
uniprot id: F8GCB7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

573569:F7308 RS00250
gene id: 573569:F7308_RS00250
uniprot id: F8G7D3
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

573569:F7308 RS02740
gene id: 573569:F7308_RS02740
uniprot id: F8GA64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

573569:F7308 RS00470
gene id: 573569:F7308_RS00470
uniprot id: F8G7H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

573569:F7308 RS03190
gene id: 573569:F7308_RS03190
uniprot id: F8GAN0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

573569:F7308 RS07500
gene id: 573569:F7308_RS07500
uniprot id: F8G8L0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573569:F7308 RS01080
gene id: 573569:F7308_RS01080
uniprot id: F8G8B2
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

573569:F7308 RS04235
gene id: 573569:F7308_RS04235
uniprot id: F8GBK9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

573569:F7308 RS05755
gene id: 573569:F7308_RS05755
uniprot id: F8G6T3
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

573569:F7308 RS01250
gene id: 573569:F7308_RS01250
uniprot id: F8G8E6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

573569:F7308 RS07125
gene id: 573569:F7308_RS07125
uniprot id: F8G856
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

573569:F7308 RS03345
gene id: 573569:F7308_RS03345
uniprot id: F8GAY8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

573569:F7308 RS05515
gene id: 573569:F7308_RS05515
uniprot id: F8GCB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

573569:F7308 RS09350
gene id: 573569:F7308_RS09350
uniprot id: F8GAS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

573569:F7308 RS09650
gene id: 573569:F7308_RS09650
uniprot id: F8GB66
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS06915
gene id: 573569:F7308_RS06915
uniprot id: F8G812
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

573569:F7308 RS09020
gene id: 573569:F7308_RS09020
uniprot id: F8GAD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

573569:F7308 RS02560
gene id: 573569:F7308_RS02560
uniprot id: F8GA28
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

573569:F7308 RS04955
gene id: 573569:F7308_RS04955
uniprot id: F8GC06
names: Similarity
messages: Belongs to the pyruvate kinase family.

573569:F7308 RS03250
gene id: 573569:F7308_RS03250
uniprot id: F8GAP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

573569:F7308 RS07460
gene id: 573569:F7308_RS07460
uniprot id: F8G8K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

573569:F7308 RS00840
gene id: 573569:F7308_RS00840
uniprot id: F8G7Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

573569:F7308 RS01205
gene id: 573569:F7308_RS01205
uniprot id: F8G8D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

573569:F7308 RS05670
gene id: 573569:F7308_RS05670
uniprot id: F8GCE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

573569:F7308 RS08200
gene id: 573569:F7308_RS08200
uniprot id: F8G9G1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

573569:F7308 RS08670
gene id: 573569:F7308_RS08670
uniprot id: F8G9Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

573569:F7308 RS06845
gene id: 573569:F7308_RS06845
uniprot id: F8G7R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

573569:F7308 RS09360
gene id: 573569:F7308_RS09360
uniprot id: F8GAS4
names: Similarity
messages: Belongs to the aspartokinase family.

573569:F7308 RS07465
gene id: 573569:F7308_RS07465
uniprot id: F8G8K4
names: Similarity
messages: Belongs to the UPF0434 family.

573569:F7308 RS05180
gene id: 573569:F7308_RS05180
uniprot id: F8GC49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

573569:F7308 RS09685
gene id: 573569:F7308_RS09685
uniprot id: F8GB73
names: Similarity
messages: Belongs to the HupF/HypC family.

573569:F7308 RS07945
gene id: 573569:F7308_RS07945
uniprot id: F8G930
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

573569:F7308 RS01290
gene id: 573569:F7308_RS01290
uniprot id: F8G8F4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

573569:F7308 RS01260
gene id: 573569:F7308_RS01260
uniprot id: F8G8E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

573569:F7308 RS00825
gene id: 573569:F7308_RS00825
uniprot id: F8G7Y1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS04260
gene id: 573569:F7308_RS04260
uniprot id: F8GBL4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

573569:F7308 RS04405
gene id: 573569:F7308_RS04405
uniprot id: F8GBP5
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

573569:F7308 RS09335
gene id: 573569:F7308_RS09335
uniprot id: F8GAR9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573569:F7308 RS01330
gene id: 573569:F7308_RS01330
uniprot id: F8G8G2
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS08630
gene id: 573569:F7308_RS08630
uniprot id: F8G9X2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

573569:F7308 RS02620
gene id: 573569:F7308_RS02620
uniprot id: F8GA40
names: Similarity
messages: Belongs to the aspartokinase family.

573569:F7308 RS00600
gene id: 573569:F7308_RS00600
uniprot id: F8G7T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

573569:F7308 RS07510
gene id: 573569:F7308_RS07510
uniprot id: F8G8L2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

573569:F7308 RS02335
gene id: 573569:F7308_RS02335
uniprot id: F8G9Q9
names: Similarity
messages: Belongs to the IMPACT family.

573569:F7308 RS06225
gene id: 573569:F7308_RS06225
uniprot id: F8G761
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS02600
gene id: 573569:F7308_RS02600
uniprot id: F8GA36
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

573569:F7308 RS08135
gene id: 573569:F7308_RS08135
uniprot id: F8G9E8
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS06975
gene id: 573569:F7308_RS06975
uniprot id: F8G824
names: Subcellular Location Annotation
messages: Cytoplasm

573569:F7308 RS08990
gene id: 573569:F7308_RS08990
uniprot id: F8GAC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

573569:F7308 RS06330
gene id: 573569:F7308_RS06330
uniprot id: F8G782
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

573569:F7308 RS01055
gene id: 573569:F7308_RS01055
uniprot id: F8G8A8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

573569:F7308 RS08540
gene id: 573569:F7308_RS08540
uniprot id: F8G9V4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

573569:F7308 RS03200
gene id: 573569:F7308_RS03200
uniprot id: F8GAN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

573569:F7308 RS01245
gene id: 573569:F7308_RS01245
uniprot id: F8G8E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

573569:F7308 RS03575
gene id: 573569:F7308_RS03575
uniprot id: F8GB33
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

573569:F7308 RS07190
gene id: 573569:F7308_RS07190
uniprot id: F8G869
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

573569:F7308 RS02875
gene id: 573569:F7308_RS02875
uniprot id: F8GA91
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

573569:F7308 RS07980
gene id: 573569:F7308_RS07980
uniprot id: F8G937
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS05100
gene id: 573569:F7308_RS05100
uniprot id: F8GC32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

573569:F7308 RS07885
gene id: 573569:F7308_RS07885
uniprot id: F8G918
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

573569:F7308 RS08850
gene id: 573569:F7308_RS08850
uniprot id: F8GA19
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

573569:F7308 RS05890
gene id: 573569:F7308_RS05890
uniprot id: F8G6W1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

573569:F7308 RS06830
gene id: 573569:F7308_RS06830
uniprot id: F8G7R4
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

573569:F7308 RS08845
gene id: 573569:F7308_RS08845
uniprot id: F8GA18
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

573569:F7308 RS01130
gene id: 573569:F7308_RS01130
uniprot id: F8G8C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

573569:F7308 RS08785
gene id: 573569:F7308_RS08785
uniprot id: F8GA06
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

573569:F7308 RS04410
gene id: 573569:F7308_RS04410
uniprot id: F8GBP6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

573569:F7308 RS08300
gene id: 573569:F7308_RS08300
uniprot id: F8G9I2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

573569:F7308 RS01125
gene id: 573569:F7308_RS01125
uniprot id: F8G8C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

573569:F7308 RS04390
gene id: 573569:F7308_RS04390
uniprot id: F8GBP2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS03325
gene id: 573569:F7308_RS03325
uniprot id: F8GAQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS01920
gene id: 573569:F7308_RS01920
uniprot id: F8G992
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

573569:F7308 RS00360
gene id: 573569:F7308_RS00360
uniprot id: F8G7F6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS00020
gene id: 573569:F7308_RS00020
uniprot id: F8G705
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS07600
gene id: 573569:F7308_RS07600
uniprot id: F8G8N0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573569:F7308 RS00810
gene id: 573569:F7308_RS00810
uniprot id: F8G7X8
names: Similarity
messages: Belongs to the glutamine synthetase family.

573569:F7308 RS06230
gene id: 573569:F7308_RS06230
uniprot id: F8G762
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

573569:F7308 RS04810
gene id: 573569:F7308_RS04810
uniprot id: F8GBX7
names: Similarity
messages: Belongs to the peptidase C59 family.

573569:F7308 RS06025
gene id: 573569:F7308_RS06025
uniprot id: F8G6Y8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

573569:F7308 RS05295
gene id: 573569:F7308_RS05295
uniprot id: F8GC72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

573569:F7308 RS08640
gene id: 573569:F7308_RS08640
uniprot id: F8G9X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

573569:F7308 RS00220
gene id: 573569:F7308_RS00220
uniprot id: F8G7C8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

573569:F7308 RS05595
gene id: 573569:F7308_RS05595
uniprot id: F8GCD1
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

573569:F7308 RS01865
gene id: 573569:F7308_RS01865
uniprot id: F8G981
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

573569:F7308 RS00290
gene id: 573569:F7308_RS00290
uniprot id: F8G7E2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

573569:F7308 RS09660
gene id: 573569:F7308_RS09660
uniprot id: F8GB68
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

573569:F7308 RS09560
gene id: 573569:F7308_RS09560
uniprot id: F8GAW9
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

573569:F7308 RS00765
gene id: 573569:F7308_RS00765
uniprot id: F8G7W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

573569:F7308 RS06160
gene id: 573569:F7308_RS06160
uniprot id: F8G748
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573569:F7308 RS08625
gene id: 573569:F7308_RS08625
uniprot id: F8G9X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

573569:F7308 RS07410
gene id: 573569:F7308_RS07410
uniprot id: F8G8J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

573569:F7308 RS07185
gene id: 573569:F7308_RS07185
uniprot id: F8G868
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

573569:F7308 RS07875
gene id: 573569:F7308_RS07875
uniprot id: F8G916
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

573569:F7308 RS07030
gene id: 573569:F7308_RS07030
uniprot id: F8G837
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

573569:F7308 RS07455
gene id: 573569:F7308_RS07455
uniprot id: F8G8K2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS03755
gene id: 573569:F7308_RS03755
uniprot id: F8GBA9
names: Function
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

573569:F7308 RS02265
gene id: 573569:F7308_RS02265
uniprot id: F8G9P4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

573569:F7308 RS08615
gene id: 573569:F7308_RS08615
uniprot id: F8G9W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

573569:F7308 RS05200
gene id: 573569:F7308_RS05200
uniprot id: F8GC53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

573569:F7308 RS00905
gene id: 573569:F7308_RS00905
uniprot id: F8G7Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

573569:F7308 RS07300
gene id: 573569:F7308_RS07300
uniprot id: F8G8H1
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS03220
gene id: 573569:F7308_RS03220
uniprot id: F8GAN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

573569:F7308 RS01145
gene id: 573569:F7308_RS01145
uniprot id: F8G8C5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

573569:F7308 RS07785
gene id: 573569:F7308_RS07785
uniprot id: F8G8Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

573569:F7308 RS08555
gene id: 573569:F7308_RS08555
uniprot id: F8G9V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

573569:F7308 RS06785
gene id: 573569:F7308_RS06785
uniprot id: F8G7Q5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

573569:F7308 RS08560
gene id: 573569:F7308_RS08560
uniprot id: F8G9V9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS08600
gene id: 573569:F7308_RS08600
uniprot id: F8G9W7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

573569:F7308 RS00440
gene id: 573569:F7308_RS00440
uniprot id: F8G7H3
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS03265
gene id: 573569:F7308_RS03265
uniprot id: F8GAP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

573569:F7308 RS04850
gene id: 573569:F7308_RS04850
uniprot id: F8GBY5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS06550
gene id: 573569:F7308_RS06550
uniprot id: F8G7K7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

573569:F7308 RS02235
gene id: 573569:F7308_RS02235
uniprot id: F8G9N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

573569:F7308 RS02385
gene id: 573569:F7308_RS02385
uniprot id: F8G9R2
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS01155
gene id: 573569:F7308_RS01155
uniprot id: F8G8C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

573569:F7308 RS02395
gene id: 573569:F7308_RS02395
uniprot id: F8G9R4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

573569:F7308 RS07625
gene id: 573569:F7308_RS07625
uniprot id: F8G8N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

573569:F7308 RS09200
gene id: 573569:F7308_RS09200
uniprot id: F8GAG9
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS05695
gene id: 573569:F7308_RS05695
uniprot id: F8GCE6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

573569:F7308 RS01660
gene id: 573569:F7308_RS01660
uniprot id: F8G8W0
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS00425
gene id: 573569:F7308_RS00425
uniprot id: F8G7H0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

573569:F7308 RS01240
gene id: 573569:F7308_RS01240
uniprot id: F8G8E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

573569:F7308 RS08715
gene id: 573569:F7308_RS08715
uniprot id: F8G9Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

573569:F7308 RS06595
gene id: 573569:F7308_RS06595
uniprot id: F8G7L6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

573569:F7308 RS02795
gene id: 573569:F7308_RS02795
uniprot id: F8GA75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

573569:F7308 RS02460
gene id: 573569:F7308_RS02460
uniprot id: F8G9S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS01310
gene id: 573569:F7308_RS01310
uniprot id: F8G8F8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

573569:F7308 RS09035
gene id: 573569:F7308_RS09035
uniprot id: F8GAD5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS05205
gene id: 573569:F7308_RS05205
uniprot id: F8GC54
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

573569:F7308 RS05130
gene id: 573569:F7308_RS05130
uniprot id: F8GC38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

573569:F7308 RS02790
gene id: 573569:F7308_RS02790
uniprot id: F8GA74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

573569:F7308 RS08215
gene id: 573569:F7308_RS08215
uniprot id: F8G9G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

573569:F7308 RS02085
gene id: 573569:F7308_RS02085
uniprot id: F8G9C7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

573569:F7308 RS05465
gene id: 573569:F7308_RS05465
uniprot id: F8GCA7
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

573569:F7308 RS02445
gene id: 573569:F7308_RS02445
uniprot id: F8G9S5
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS07645
gene id: 573569:F7308_RS07645
uniprot id: F8G8P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

573569:F7308 RS09120
gene id: 573569:F7308_RS09120
uniprot id: F8GAF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

573569:F7308 RS06070
gene id: 573569:F7308_RS06070
uniprot id: F8G6Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS01185
gene id: 573569:F7308_RS01185
uniprot id: F8G8D3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

573569:F7308 RS05345
gene id: 573569:F7308_RS05345
uniprot id: F8GC82
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

573569:F7308 RS09250
gene id: 573569:F7308_RS09250
uniprot id: F8GAH9
names: Subcellular Location Annotation
messages: Cytoplasm

573569:F7308 RS08645
gene id: 573569:F7308_RS08645
uniprot id: F8G9X5
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

573569:F7308 RS08410
gene id: 573569:F7308_RS08410
uniprot id: F8G9K3
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS01775
gene id: 573569:F7308_RS01775
uniprot id: F8G963
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

573569:F7308 RS09565
gene id: 573569:F7308_RS09565
uniprot id: F8GAX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

573569:F7308 RS01610
gene id: 573569:F7308_RS01610
uniprot id: F8G8U9
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS09835
gene id: 573569:F7308_RS09835
uniprot id: F8GBA4
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

573569:F7308 RS01765
gene id: 573569:F7308_RS01765
uniprot id: F8G961
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

573569:F7308 RS04720
gene id: 573569:F7308_RS04720
uniprot id: F8GBW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

573569:F7308 RS05930
gene id: 573569:F7308_RS05930
uniprot id: F8G6W9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

573569:F7308 RS05110
gene id: 573569:F7308_RS05110
uniprot id: F8GC34
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS07175
gene id: 573569:F7308_RS07175
uniprot id: F8G866
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

573569:F7308 RS06270
gene id: 573569:F7308_RS06270
uniprot id: F8G770
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

573569:F7308 RS01315
gene id: 573569:F7308_RS01315
uniprot id: F8G8F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

573569:F7308 RS05910
gene id: 573569:F7308_RS05910
uniprot id: F8G6W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

573569:F7308 RS07990
gene id: 573569:F7308_RS07990
uniprot id: F8G939
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS01180
gene id: 573569:F7308_RS01180
uniprot id: F8G8D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

573569:F7308 RS08930
gene id: 573569:F7308_RS08930
uniprot id: F8GAB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that is essential for cell division.

573569:F7308 RS07265
gene id: 573569:F7308_RS07265
uniprot id: F8G884
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

573569:F7308 RS01955
gene id: 573569:F7308_RS01955
uniprot id: F8G999
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

573569:F7308 RS09300
gene id: 573569:F7308_RS09300
uniprot id: F8GAR7
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS03355
gene id: 573569:F7308_RS03355
uniprot id: F8GAZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

573569:F7308 RS01575
gene id: 573569:F7308_RS01575
uniprot id: F8G8U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

573569:F7308 RS06375
gene id: 573569:F7308_RS06375
uniprot id: F8G791
names: Similarity
messages: Belongs to the YjdM family.

573569:F7308 RS07640
gene id: 573569:F7308_RS07640
uniprot id: F8G8N9
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

573569:F7308 RS01995
gene id: 573569:F7308_RS01995
uniprot id: F8G9A7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

573569:F7308 RS00280
gene id: 573569:F7308_RS00280
uniprot id: F8G7D9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

573569:F7308 RS05225
gene id: 573569:F7308_RS05225
uniprot id: F8GC58
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

573569:F7308 RS08575
gene id: 573569:F7308_RS08575
uniprot id: F8G9W2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

573569:F7308 RS08885
gene id: 573569:F7308_RS08885
uniprot id: F8GAA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

573569:F7308 RS07685
gene id: 573569:F7308_RS07685
uniprot id: F8G8P8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

573569:F7308 RS00465
gene id: 573569:F7308_RS00465
uniprot id: F8G7H7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

573569:F7308 RS02710
gene id: 573569:F7308_RS02710
uniprot id: F8GA59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS05175
gene id: 573569:F7308_RS05175
uniprot id: F8GC48
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

573569:F7308 RS05750
gene id: 573569:F7308_RS05750
uniprot id: F8G6T2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

573569:F7308 RS02800
gene id: 573569:F7308_RS02800
uniprot id: F8GA76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

573569:F7308 RS03330
gene id: 573569:F7308_RS03330
uniprot id: F8GAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

573569:F7308 RS03045
gene id: 573569:F7308_RS03045
uniprot id: F8GAK5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

573569:F7308 RS09715
gene id: 573569:F7308_RS09715
uniprot id: F8GB79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

573569:F7308 RS09130
gene id: 573569:F7308_RS09130
uniprot id: F8GAF4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

573569:F7308 RS00865
gene id: 573569:F7308_RS00865
uniprot id: F8G7Y9
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS07215
gene id: 573569:F7308_RS07215
uniprot id: F8G874
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

573569:F7308 RS08435
gene id: 573569:F7308_RS08435
uniprot id: F8G9K8
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS00515
gene id: 573569:F7308_RS00515
uniprot id: F8G7I7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

573569:F7308 RS08820
gene id: 573569:F7308_RS08820
uniprot id: F8GA13
names: Similarity
messages: Belongs to the RecJ family.

573569:F7308 RS02865
gene id: 573569:F7308_RS02865
uniprot id: F8GA89
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

573569:F7308 RS05660
gene id: 573569:F7308_RS05660
uniprot id: F8GCD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

573569:F7308 RS02240
gene id: 573569:F7308_RS02240
uniprot id: F8G9N9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

573569:F7308 RS00210
gene id: 573569:F7308_RS00210
uniprot id: F8G7C6
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

573569:F7308 RS03070
gene id: 573569:F7308_RS03070
uniprot id: F8GAL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

573569:F7308 RS03510
gene id: 573569:F7308_RS03510
uniprot id: F8GB20
names: Similarity
messages: Belongs to the peptidase S8 family.

573569:F7308 RS03955
gene id: 573569:F7308_RS03955
uniprot id: F8GBF3
names: Similarity
messages: Belongs to the Skp family.

573569:F7308 RS06680
gene id: 573569:F7308_RS06680
uniprot id: F8G7N3
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS06960
gene id: 573569:F7308_RS06960
uniprot id: F8G821
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

573569:F7308 RS04065
gene id: 573569:F7308_RS04065
uniprot id: F8GBH4
names: Similarity
messages: Belongs to the CFA/CMAS family.

573569:F7308 RS06390
gene id: 573569:F7308_RS06390
uniprot id: F8G794
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

573569:F7308 RS01210
gene id: 573569:F7308_RS01210
uniprot id: F8G8D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

573569:F7308 RS02495
gene id: 573569:F7308_RS02495
uniprot id: F8G9T5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

573569:F7308 RS07870
gene id: 573569:F7308_RS07870
uniprot id: F8G915
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

573569:F7308 RS07925
gene id: 573569:F7308_RS07925
uniprot id: F8G926
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

573569:F7308 RS09340
gene id: 573569:F7308_RS09340
uniprot id: F8GAS0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

573569:F7308 RS07430
gene id: 573569:F7308_RS07430
uniprot id: F8G8J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

573569:F7308 RS07830
gene id: 573569:F7308_RS07830
uniprot id: F8G907
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

573569:F7308 RS03980
gene id: 573569:F7308_RS03980
uniprot id: F8GBF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

573569:F7308 RS02405
gene id: 573569:F7308_RS02405
uniprot id: F8G9R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

573569:F7308 RS08205
gene id: 573569:F7308_RS08205
uniprot id: F8G9G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

573569:F7308 RS01485
gene id: 573569:F7308_RS01485
uniprot id: F8G8S5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

573569:F7308 RS04015
gene id: 573569:F7308_RS04015
uniprot id: F8GBG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

573569:F7308 RS07700
gene id: 573569:F7308_RS07700
uniprot id: F8G8Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

573569:F7308 RS06965
gene id: 573569:F7308_RS06965
uniprot id: F8G822
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

573569:F7308 RS00335
gene id: 573569:F7308_RS00335
uniprot id: F8G7F1
names: Similarity
messages: Belongs to the universal stress protein A family.

573569:F7308 RS00195
gene id: 573569:F7308_RS00195
uniprot id: F8G7C3
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS00750
gene id: 573569:F7308_RS00750
uniprot id: F8G7W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

573569:F7308 RS07135
gene id: 573569:F7308_RS07135
uniprot id: F8G858
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

573569:F7308 RS00830
gene id: 573569:F7308_RS00830
uniprot id: F8G7Y2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

573569:F7308 RS08365
gene id: 573569:F7308_RS08365
uniprot id: F8G9J4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

573569:F7308 RS01875
gene id: 573569:F7308_RS01875
uniprot id: F8G983
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

573569:F7308 RS00805
gene id: 573569:F7308_RS00805
uniprot id: F8G7X7
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

573569:F7308 RS05715
gene id: 573569:F7308_RS05715
uniprot id: F8G6S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

573569:F7308 RS09665
gene id: 573569:F7308_RS09665
uniprot id: F8GB69
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

573569:F7308 RS01420
gene id: 573569:F7308_RS01420
uniprot id: F8G8R1
names: Similarity
messages: Belongs to the YciI family.

573569:F7308 RS07070
gene id: 573569:F7308_RS07070
uniprot id: F8G845
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

573569:F7308 RS02035
gene id: 573569:F7308_RS02035
uniprot id: F8G9B7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

573569:F7308 RS04820
gene id: 573569:F7308_RS04820
uniprot id: F8GBX9
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

573569:F7308 RS02885
gene id: 573569:F7308_RS02885
uniprot id: F8GA93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573569:F7308 RS04830
gene id: 573569:F7308_RS04830
uniprot id: F8GBY1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

573569:F7308 RS07720
gene id: 573569:F7308_RS07720
uniprot id: F8G8Y4
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS03840
gene id: 573569:F7308_RS03840
uniprot id: F8GBC8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

573569:F7308 RS08810
gene id: 573569:F7308_RS08810
uniprot id: F8GA11
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS06460
gene id: 573569:F7308_RS06460
uniprot id: F8G7A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

573569:F7308 RS03550
gene id: 573569:F7308_RS03550
uniprot id: F8GB28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

573569:F7308 RS05945
gene id: 573569:F7308_RS05945
uniprot id: F8G6X2
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

573569:F7308 RS09570
gene id: 573569:F7308_RS09570
uniprot id: F8GAX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

573569:F7308 RS09345
gene id: 573569:F7308_RS09345
uniprot id: F8GAS1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

573569:F7308 RS00390
gene id: 573569:F7308_RS00390
uniprot id: F8G7G2
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS08510
gene id: 573569:F7308_RS08510
uniprot id: F8G9U8
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

573569:F7308 RS03450
gene id: 573569:F7308_RS03450
uniprot id: F8GB09
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

573569:F7308 RS02245
gene id: 573569:F7308_RS02245
uniprot id: F8G9P0
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

573569:F7308 RS00200
gene id: 573569:F7308_RS00200
uniprot id: F8G7C4
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS09295
gene id: 573569:F7308_RS09295
uniprot id: F8GAR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS05230
gene id: 573569:F7308_RS05230
uniprot id: F8GC59
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573569:F7308 RS05925
gene id: 573569:F7308_RS05925
uniprot id: F8G6W8
names: Similarity
messages: Belongs to the RNase T2 family.

573569:F7308 RS06210
gene id: 573569:F7308_RS06210
uniprot id: F8G758
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

573569:F7308 RS02665
gene id: 573569:F7308_RS02665
uniprot id: F8GA50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

573569:F7308 RS00965
gene id: 573569:F7308_RS00965
uniprot id: F8G891
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

573569:F7308 RS08420
gene id: 573569:F7308_RS08420
uniprot id: F8G9K5
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS00225
gene id: 573569:F7308_RS00225
uniprot id: F8G7C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

573569:F7308 RS05895
gene id: 573569:F7308_RS05895
uniprot id: F8G6W2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

573569:F7308 RS02840
gene id: 573569:F7308_RS02840
uniprot id: F8GA84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

573569:F7308 RS05665
gene id: 573569:F7308_RS05665
uniprot id: F8GCE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

573569:F7308 RS00525
gene id: 573569:F7308_RS00525
uniprot id: F8G7I9
names: Similarity
messages: Belongs to the peptidase S49 family.

573569:F7308 RS01095
gene id: 573569:F7308_RS01095
uniprot id: F8G8B5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS07485
gene id: 573569:F7308_RS07485
uniprot id: F8G8K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

573569:F7308 RS07025
gene id: 573569:F7308_RS07025
uniprot id: F8G836
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

573569:F7308 RS04880
gene id: 573569:F7308_RS04880
uniprot id: F8GBZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

573569:F7308 RS09135
gene id: 573569:F7308_RS09135
uniprot id: F8GAF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

573569:F7308 RS00890
gene id: 573569:F7308_RS00890
uniprot id: F8G7Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

573569:F7308 RS09935
gene id: 573569:F7308_RS09935
uniprot id: F8GB93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS07140
gene id: 573569:F7308_RS07140
uniprot id: F8G859
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

573569:F7308 RS02830
gene id: 573569:F7308_RS02830
uniprot id: F8GA82
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS00415
gene id: 573569:F7308_RS00415
uniprot id: F8G7G8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS01175
gene id: 573569:F7308_RS01175
uniprot id: F8G8D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

573569:F7308 RS08950
gene id: 573569:F7308_RS08950
uniprot id: F8GAB8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573569:F7308 RS05545
gene id: 573569:F7308_RS05545
uniprot id: F8GCC1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

573569:F7308 RS09110
gene id: 573569:F7308_RS09110
uniprot id: F8GAF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

573569:F7308 RS04045
gene id: 573569:F7308_RS04045
uniprot id: F8GBH0
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS05485
gene id: 573569:F7308_RS05485
uniprot id: F8GCB1
names: Similarity
messages: Belongs to the LOG family.

573569:F7308 RS09725
gene id: 573569:F7308_RS09725
uniprot id: F8GB81
names: Similarity
messages: Belongs to the peptidase A31 family.

573569:F7308 RS09800
gene id: 573569:F7308_RS09800
uniprot id: F8GB97
names: Similarity
messages: Belongs to the peptidase M1 family.

573569:F7308 RS01230
gene id: 573569:F7308_RS01230
uniprot id: F8G8E2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

573569:F7308 RS09755
gene id: 573569:F7308_RS09755
uniprot id: F8GB88
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS02745
gene id: 573569:F7308_RS02745
uniprot id: F8GA65
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS01735
gene id: 573569:F7308_RS01735
uniprot id: F8G8X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

573569:F7308 RS05810
gene id: 573569:F7308_RS05810
uniprot id: F8G6U4
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS08955
gene id: 573569:F7308_RS08955
uniprot id: F8GAB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

573569:F7308 RS06760
gene id: 573569:F7308_RS06760
uniprot id: F8G7Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

573569:F7308 RS06815
gene id: 573569:F7308_RS06815
uniprot id: F8G7R1
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS03495
gene id: 573569:F7308_RS03495
uniprot id: F8GB17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

573569:F7308 RS01265
gene id: 573569:F7308_RS01265
uniprot id: F8G8E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

573569:F7308 RS07440
gene id: 573569:F7308_RS07440
uniprot id: F8G8J9
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

573569:F7308 RS05255
gene id: 573569:F7308_RS05255
uniprot id: F8GC64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

573569:F7308 RS07115
gene id: 573569:F7308_RS07115
uniprot id: F8G854
names: Similarity
messages: Belongs to the peptidase S13 family.

573569:F7308 RS04210
gene id: 573569:F7308_RS04210
uniprot id: F8GBK4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS08460
gene id: 573569:F7308_RS08460
uniprot id: F8G9L3
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS08165
gene id: 573569:F7308_RS08165
uniprot id: F8G9F4
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

573569:F7308 RS04040
gene id: 573569:F7308_RS04040
uniprot id: F8GBG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

573569:F7308 RS05350
gene id: 573569:F7308_RS05350
uniprot id: F8GC83
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

573569:F7308 RS06580
gene id: 573569:F7308_RS06580
uniprot id: F8G7L3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS08465
gene id: 573569:F7308_RS08465
uniprot id: F8G9L4
names: Similarity
messages: Belongs to the peptidase S13 family.

573569:F7308 RS09840
gene id: 573569:F7308_RS09840
uniprot id: F8GBA5
names: Similarity
messages: Belongs to the TrpR family.

573569:F7308 RS00760
gene id: 573569:F7308_RS00760
uniprot id: F8G7W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

573569:F7308 RS03505
gene id: 573569:F7308_RS03505
uniprot id: F8GB19
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

573569:F7308 RS02325
gene id: 573569:F7308_RS02325
uniprot id: F8G9Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

573569:F7308 RS00790
gene id: 573569:F7308_RS00790
uniprot id: F8G7X4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

573569:F7308 RS02435
gene id: 573569:F7308_RS02435
uniprot id: F8G9S3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS06410
gene id: 573569:F7308_RS06410
uniprot id: F8G798
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

573569:F7308 RS06525
gene id: 573569:F7308_RS06525
uniprot id: F8G7K2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

573569:F7308 RS02110
gene id: 573569:F7308_RS02110
uniprot id: F8G9D3
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

573569:F7308 RS07075
gene id: 573569:F7308_RS07075
uniprot id: F8G846
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

573569:F7308 RS03800
gene id: 573569:F7308_RS03800
uniprot id: F8GBB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS08430
gene id: 573569:F7308_RS08430
uniprot id: F8G9K7
names: Similarity
messages: Belongs to the RutC family.

573569:F7308 RS04895
gene id: 573569:F7308_RS04895
uniprot id: F8GBZ4
names: Similarity
messages: Belongs to the YciI family.

573569:F7308 RS06340
gene id: 573569:F7308_RS06340
uniprot id: F8G784
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

573569:F7308 RS06130
gene id: 573569:F7308_RS06130
uniprot id: F8G743
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573569:F7308 RS00705
gene id: 573569:F7308_RS00705
uniprot id: F8G7V7
names: Similarity
messages: Belongs to the YggT family.

573569:F7308 RS02125
gene id: 573569:F7308_RS02125
uniprot id: F8G9D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

573569:F7308 RS03235
gene id: 573569:F7308_RS03235
uniprot id: F8GAN9
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS04355
gene id: 573569:F7308_RS04355
uniprot id: F8GBN5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

573569:F7308 RS02510
gene id: 573569:F7308_RS02510
uniprot id: F8G9T8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS04975
gene id: 573569:F7308_RS04975
uniprot id: F8GC10
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

573569:F7308 RS04230
gene id: 573569:F7308_RS04230
uniprot id: F8GBK8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

573569:F7308 RS00310
gene id: 573569:F7308_RS00310
uniprot id: F8G7E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

573569:F7308 RS04220
gene id: 573569:F7308_RS04220
uniprot id: F8GBK6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

573569:F7308 RS08965
gene id: 573569:F7308_RS08965
uniprot id: F8GAC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

573569:F7308 RS07750
gene id: 573569:F7308_RS07750
uniprot id: F8G8Z0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

573569:F7308 RS05305
gene id: 573569:F7308_RS05305
uniprot id: F8GC74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS09220
gene id: 573569:F7308_RS09220
uniprot id: F8GAH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

573569:F7308 RS03940
gene id: 573569:F7308_RS03940
uniprot id: F8GBF0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

573569:F7308 RS06120
gene id: 573569:F7308_RS06120
uniprot id: F8G741
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

573569:F7308 RS05235
gene id: 573569:F7308_RS05235
uniprot id: F8GC60
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS04025
gene id: 573569:F7308_RS04025
uniprot id: F8GBG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

573569:F7308 RS03000
gene id: 573569:F7308_RS03000
uniprot id: F8GAJ6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

573569:F7308 RS06885
gene id: 573569:F7308_RS06885
uniprot id: F8G7S5
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS09680
gene id: 573569:F7308_RS09680
uniprot id: F8GB72
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

573569:F7308 RS06250
gene id: 573569:F7308_RS06250
uniprot id: F8G766
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

573569:F7308 RS03095
gene id: 573569:F7308_RS03095
uniprot id: F8GAL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

573569:F7308 RS06415
gene id: 573569:F7308_RS06415
uniprot id: F8G799
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

573569:F7308 RS03060
gene id: 573569:F7308_RS03060
uniprot id: F8GAK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

573569:F7308 RS00555
gene id: 573569:F7308_RS00555
uniprot id: F8G7J5
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

573569:F7308 RS04790
gene id: 573569:F7308_RS04790
uniprot id: F8GBX3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

573569:F7308 RS01090
gene id: 573569:F7308_RS01090
uniprot id: F8G8B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

573569:F7308 RS00495
gene id: 573569:F7308_RS00495
uniprot id: F8G7I3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

573569:F7308 RS06805
gene id: 573569:F7308_RS06805
uniprot id: F8G7Q9
names: Similarity
messages: Belongs to the thioredoxin family.

573569:F7308 RS07150
gene id: 573569:F7308_RS07150
uniprot id: F8G861
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS04825
gene id: 573569:F7308_RS04825
uniprot id: F8GBY0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS06910
gene id: 573569:F7308_RS06910
uniprot id: F8G811
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS04775
gene id: 573569:F7308_RS04775
uniprot id: F8GBX0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

573569:F7308 RS07295
gene id: 573569:F7308_RS07295
uniprot id: F8G8H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

573569:F7308 RS02605
gene id: 573569:F7308_RS02605
uniprot id: F8GA37
names: Similarity
messages: Belongs to the IucA/IucC family.

573569:F7308 RS07035
gene id: 573569:F7308_RS07035
uniprot id: F8G838
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS00530
gene id: 573569:F7308_RS00530
uniprot id: F8G7J0
names: Similarity
messages: Belongs to the Skp family.

573569:F7308 RS02475
gene id: 573569:F7308_RS02475
uniprot id: F8G9T1
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS01840
gene id: 573569:F7308_RS01840
uniprot id: F8G976
names: Similarity
messages: Belongs to the DprA/Smf family.

573569:F7308 RS08105
gene id: 573569:F7308_RS08105
uniprot id: F8G9E2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

573569:F7308 RS04240
gene id: 573569:F7308_RS04240
uniprot id: F8GBL0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

573569:F7308 RS05135
gene id: 573569:F7308_RS05135
uniprot id: F8GC39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

573569:F7308 RS07400
gene id: 573569:F7308_RS07400
uniprot id: F8G8J1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

573569:F7308 RS00100
gene id: 573569:F7308_RS00100
uniprot id: F8G722
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS00885
gene id: 573569:F7308_RS00885
uniprot id: F8G7Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

573569:F7308 RS01225
gene id: 573569:F7308_RS01225
uniprot id: F8G8E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

573569:F7308 RS02135
gene id: 573569:F7308_RS02135
uniprot id: F8G9D8
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

573569:F7308 RS04905
gene id: 573569:F7308_RS04905
uniprot id: F8GBZ6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

573569:F7308 RS07330
gene id: 573569:F7308_RS07330
uniprot id: F8G8H8
names: Similarity
messages: Belongs to the peptidase C59 family.

573569:F7308 RS00770
gene id: 573569:F7308_RS00770
uniprot id: F8G7X0
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

573569:F7308 RS06185
gene id: 573569:F7308_RS06185
uniprot id: F8G753
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

573569:F7308 RS04910
gene id: 573569:F7308_RS04910
uniprot id: F8GBZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

573569:F7308 RS08325
gene id: 573569:F7308_RS08325
uniprot id: F8G9I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

573569:F7308 RS03085
gene id: 573569:F7308_RS03085
uniprot id: F8GAL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

573569:F7308 RS03490
gene id: 573569:F7308_RS03490
uniprot id: F8GB16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

573569:F7308 RS02870
gene id: 573569:F7308_RS02870
uniprot id: F8GA90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

573569:F7308 RS02970
gene id: 573569:F7308_RS02970
uniprot id: F8GAI9
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

573569:F7308 RS06575
gene id: 573569:F7308_RS06575
uniprot id: F8G7L2
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS09720
gene id: 573569:F7308_RS09720
uniprot id: F8GB80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

573569:F7308 RS06865
gene id: 573569:F7308_RS06865
uniprot id: F8G7S1
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS09125
gene id: 573569:F7308_RS09125
uniprot id: F8GAF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

573569:F7308 RS09095
gene id: 573569:F7308_RS09095
uniprot id: F8GAE7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

573569:F7308 RS04215
gene id: 573569:F7308_RS04215
uniprot id: F8GBK5
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

573569:F7308 RS01070
gene id: 573569:F7308_RS01070
uniprot id: F8G8B0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

573569:F7308 RS02225
gene id: 573569:F7308_RS02225
uniprot id: F8G9N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

573569:F7308 RS02315
gene id: 573569:F7308_RS02315
uniprot id: F8G9Q5
names: Similarity
messages: Belongs to the bacterial glucokinase family.

573569:F7308 RS02120
gene id: 573569:F7308_RS02120
uniprot id: F8G9D5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS04145
gene id: 573569:F7308_RS04145
uniprot id: F8GBJ0
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS10150
gene id: 573569:F7308_RS10150
uniprot id: F8G715
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

573569:F7308 RS05195
gene id: 573569:F7308_RS05195
uniprot id: F8GC52
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

573569:F7308 RS05395
gene id: 573569:F7308_RS05395
uniprot id: F8GC92
names: Similarity
messages: Belongs to the BolA/IbaG family.

573569:F7308 RS01100
gene id: 573569:F7308_RS01100
uniprot id: F8G8B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

573569:F7308 RS07425
gene id: 573569:F7308_RS07425
uniprot id: F8G8J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

573569:F7308 RS07255
gene id: 573569:F7308_RS07255
uniprot id: F8G882
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

573569:F7308 RS06220
gene id: 573569:F7308_RS06220
uniprot id: F8G760
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS00490
gene id: 573569:F7308_RS00490
uniprot id: F8G7I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

573569:F7308 RS05900
gene id: 573569:F7308_RS05900
uniprot id: F8G6W3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

573569:F7308 RS03105
gene id: 573569:F7308_RS03105
uniprot id: F8GAL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

573569:F7308 RS09600
gene id: 573569:F7308_RS09600
uniprot id: F8GAX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

573569:F7308 RS03415
gene id: 573569:F7308_RS03415
uniprot id: F8GB02
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

573569:F7308 RS04205
gene id: 573569:F7308_RS04205
uniprot id: F8GBK3
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

573569:F7308 RS06450
gene id: 573569:F7308_RS06450
uniprot id: F8G7A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

573569:F7308 RS04815
gene id: 573569:F7308_RS04815
uniprot id: F8GBX8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

573569:F7308 RS06090
gene id: 573569:F7308_RS06090
uniprot id: F8G701
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

573569:F7308 RS03175
gene id: 573569:F7308_RS03175
uniprot id: F8GAM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

573569:F7308 RS01385
gene id: 573569:F7308_RS01385
uniprot id: F8G8Q4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

573569:F7308 RS08015
gene id: 573569:F7308_RS08015
uniprot id: F8G944
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

573569:F7308 RS02415
gene id: 573569:F7308_RS02415
uniprot id: F8G9R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

573569:F7308 RS06755
gene id: 573569:F7308_RS06755
uniprot id: F8G7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS04595
gene id: 573569:F7308_RS04595
uniprot id: F8GBT4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

573569:F7308 RS00005
gene id: 573569:F7308_RS00005
uniprot id: F8G702
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

573569:F7308 RS00740
gene id: 573569:F7308_RS00740
uniprot id: F8G7W4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

573569:F7308 RS00575
gene id: 573569:F7308_RS00575
uniprot id: F8G7T0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

573569:F7308 RS03640
gene id: 573569:F7308_RS03640
uniprot id: F8GB46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

573569:F7308 RS05630
gene id: 573569:F7308_RS05630
uniprot id: F8GCD3
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS07975
gene id: 573569:F7308_RS07975
uniprot id: F8G936
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

573569:F7308 RS06015
gene id: 573569:F7308_RS06015
uniprot id: F8G6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

573569:F7308 RS01115
gene id: 573569:F7308_RS01115
uniprot id: F8G8B9
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

573569:F7308 RS03965
gene id: 573569:F7308_RS03965
uniprot id: F8GBF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

573569:F7308 RS04840
gene id: 573569:F7308_RS04840
uniprot id: F8GBY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

573569:F7308 RS09070
gene id: 573569:F7308_RS09070
uniprot id: F8GAE2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

573569:F7308 RS00875
gene id: 573569:F7308_RS00875
uniprot id: F8G7Z1
names: Similarity
messages: Belongs to the WrbA family.

573569:F7308 RS04130
gene id: 573569:F7308_RS04130
uniprot id: F8GBI7
names: Similarity
messages: Belongs to the arginase family.

573569:F7308 RS04630
gene id: 573569:F7308_RS04630
uniprot id: F8GBU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS03240
gene id: 573569:F7308_RS03240
uniprot id: F8GAP0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS01255
gene id: 573569:F7308_RS01255
uniprot id: F8G8E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

573569:F7308 RS02490
gene id: 573569:F7308_RS02490
uniprot id: F8G9T4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

573569:F7308 RS01045
gene id: 573569:F7308_RS01045
uniprot id: F8G8A6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

573569:F7308 RS06950
gene id: 573569:F7308_RS06950
uniprot id: F8G819
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

573569:F7308 RS08040
gene id: 573569:F7308_RS08040
uniprot id: F8G949
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

573569:F7308 RS08295
gene id: 573569:F7308_RS08295
uniprot id: F8G9I1
names: Similarity
messages: Belongs to the peptidase M16 family.

573569:F7308 RS07395
gene id: 573569:F7308_RS07395
uniprot id: F8G8J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

573569:F7308 RS03055
gene id: 573569:F7308_RS03055
uniprot id: F8GAK7
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

573569:F7308 RS10425
gene id: 573569:F7308_RS10425
uniprot id: F8G9F3
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

573569:F7308 RS03110
gene id: 573569:F7308_RS03110
uniprot id: F8GAL8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

573569:F7308 RS01715
gene id: 573569:F7308_RS01715
uniprot id: F8G8X0
names: Similarity
messages: Belongs to the BolA/IbaG family.

573569:F7308 RS02585
gene id: 573569:F7308_RS02585
uniprot id: F8GA33
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS02005
gene id: 573569:F7308_RS02005
uniprot id: F8G9A9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

573569:F7308 RS08860
gene id: 573569:F7308_RS08860
uniprot id: F8GA21
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

573569:F7308 RS07010
gene id: 573569:F7308_RS07010
uniprot id: F8G833
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

573569:F7308 RS04225
gene id: 573569:F7308_RS04225
uniprot id: F8GBK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

573569:F7308 RS01380
gene id: 573569:F7308_RS01380
uniprot id: F8G8Q3
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

573569:F7308 RS05290
gene id: 573569:F7308_RS05290
uniprot id: F8GC71
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

573569:F7308 RS05990
gene id: 573569:F7308_RS05990
uniprot id: F8G6Y1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

573569:F7308 RS07770
gene id: 573569:F7308_RS07770
uniprot id: F8G8Z5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

573569:F7308 RS09140
gene id: 573569:F7308_RS09140
uniprot id: F8GAF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

573569:F7308 RS02595
gene id: 573569:F7308_RS02595
uniprot id: F8GA35
names: Similarity
messages: Belongs to the IucA/IucC family.

573569:F7308 RS03275
gene id: 573569:F7308_RS03275
uniprot id: F8GAP7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

573569:F7308 RS08440
gene id: 573569:F7308_RS08440
uniprot id: F8G9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

573569:F7308 RS01160
gene id: 573569:F7308_RS01160
uniprot id: F8G8C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

573569:F7308 RS06540
gene id: 573569:F7308_RS06540
uniprot id: F8G7K5
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS02690
gene id: 573569:F7308_RS02690
uniprot id: F8GA55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

573569:F7308 RS07610
gene id: 573569:F7308_RS07610
uniprot id: F8G8N2
names: Similarity
messages: Belongs to the FMO family.

573569:F7308 RS02725
gene id: 573569:F7308_RS02725
uniprot id: F8GA61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

573569:F7308 RS03950
gene id: 573569:F7308_RS03950
uniprot id: F8GBF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

573569:F7308 RS07915
gene id: 573569:F7308_RS07915
uniprot id: F8G924
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

573569:F7308 RS05460
gene id: 573569:F7308_RS05460
uniprot id: F8GCA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

573569:F7308 RS07290
gene id: 573569:F7308_RS07290
uniprot id: F8G889
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

573569:F7308 RS04960
gene id: 573569:F7308_RS04960
uniprot id: F8GC07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

573569:F7308 RS05685
gene id: 573569:F7308_RS05685
uniprot id: F8GCE4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

573569:F7308 RS00835
gene id: 573569:F7308_RS00835
uniprot id: F8G7Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

573569:F7308 RS08240
gene id: 573569:F7308_RS08240
uniprot id: F8G9G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

573569:F7308 RS08075
gene id: 573569:F7308_RS08075
uniprot id: F8G956
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

573569:F7308 RS01415
gene id: 573569:F7308_RS01415
uniprot id: F8G8R0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

573569:F7308 RS08635
gene id: 573569:F7308_RS08635
uniprot id: F8G9X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

573569:F7308 RS01285
gene id: 573569:F7308_RS01285
uniprot id: F8G8F3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

573569:F7308 RS05815
gene id: 573569:F7308_RS05815
uniprot id: F8G6U5
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS09230
gene id: 573569:F7308_RS09230
uniprot id: F8GAH5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

573569:F7308 RS07520
gene id: 573569:F7308_RS07520
uniprot id: F8G8L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

573569:F7308 RS09365
gene id: 573569:F7308_RS09365
uniprot id: F8GAS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

573569:F7308 RS07570
gene id: 573569:F7308_RS07570
uniprot id: F8G8M4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

573569:F7308 RS04870
gene id: 573569:F7308_RS04870
uniprot id: F8GBY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

573569:F7308 RS08815
gene id: 573569:F7308_RS08815
uniprot id: F8GA12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

573569:F7308 RS02705
gene id: 573569:F7308_RS02705
uniprot id: F8GA58
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

573569:F7308 RS01030
gene id: 573569:F7308_RS01030
uniprot id: F8G8A3
names: Similarity
messages: Belongs to the nitroreductase family.

573569:F7308 RS03090
gene id: 573569:F7308_RS03090
uniprot id: F8GAL4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

573569:F7308 RS03065
gene id: 573569:F7308_RS03065
uniprot id: F8GAK9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS09255
gene id: 573569:F7308_RS09255
uniprot id: F8GAI0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

573569:F7308 RS06685
gene id: 573569:F7308_RS06685
uniprot id: F8G7N4
names: Similarity
messages: Belongs to the UPF0145 family.

573569:F7308 RS02855
gene id: 573569:F7308_RS02855
uniprot id: F8GA87
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

573569:F7308 RS04935
gene id: 573569:F7308_RS04935
uniprot id: F8GC02
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

573569:F7308 RS07865
gene id: 573569:F7308_RS07865
uniprot id: F8G914
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

573569:F7308 RS05780
gene id: 573569:F7308_RS05780
uniprot id: F8G6T8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

573569:F7308 RS04395
gene id: 573569:F7308_RS04395
uniprot id: F8GBP3
names: Similarity
messages: Belongs to the thioredoxin family.

573569:F7308 RS07065
gene id: 573569:F7308_RS07065
uniprot id: F8G844
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

573569:F7308 RS08370
gene id: 573569:F7308_RS08370
uniprot id: F8G9J5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS01220
gene id: 573569:F7308_RS01220
uniprot id: F8G8E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

573569:F7308 RS02145
gene id: 573569:F7308_RS02145
uniprot id: F8G9E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

573569:F7308 RS07350
gene id: 573569:F7308_RS07350
uniprot id: F8G8I2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS03535
gene id: 573569:F7308_RS03535
uniprot id: F8GB25
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

573569:F7308 RS05455
gene id: 573569:F7308_RS05455
uniprot id: F8GCA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS03650
gene id: 573569:F7308_RS03650
uniprot id: F8GB48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

573569:F7308 RS03210
gene id: 573569:F7308_RS03210
uniprot id: F8GAN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

573569:F7308 RS01300
gene id: 573569:F7308_RS01300
uniprot id: F8G8F6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

573569:F7308 RS03635
gene id: 573569:F7308_RS03635
uniprot id: F8GB45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

573569:F7308 RS07705
gene id: 573569:F7308_RS07705
uniprot id: F8G8Y2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

573569:F7308 RS01085
gene id: 573569:F7308_RS01085
uniprot id: F8G8B3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

573569:F7308 RS06890
gene id: 573569:F7308_RS06890
uniprot id: F8G7S6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

573569:F7308 RS07955
gene id: 573569:F7308_RS07955
uniprot id: F8G932
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573569:F7308 RS02780
gene id: 573569:F7308_RS02780
uniprot id: F8GA72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

573569:F7308 RS04925
gene id: 573569:F7308_RS04925
uniprot id: F8GC00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

573569:F7308 RS09585
gene id: 573569:F7308_RS09585
uniprot id: F8GAX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

573569:F7308 RS03375
gene id: 573569:F7308_RS03375
uniprot id: F8GAZ4
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS08680
gene id: 573569:F7308_RS08680
uniprot id: F8G9Y2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

573569:F7308 RS06855
gene id: 573569:F7308_RS06855
uniprot id: F8G7R9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573569:F7308 RS02835
gene id: 573569:F7308_RS02835
uniprot id: F8GA83
names: Similarity
messages: Belongs to the citrate synthase family.

573569:F7308 RS02095
gene id: 573569:F7308_RS02095
uniprot id: F8G9D0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

573569:F7308 RS03910
gene id: 573569:F7308_RS03910
uniprot id: F8GBE2
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

573569:F7308 RS08185
gene id: 573569:F7308_RS08185
uniprot id: F8G9F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573569:F7308 RS01355
gene id: 573569:F7308_RS01355
uniprot id: F8G8G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

573569:F7308 RS00570
gene id: 573569:F7308_RS00570
uniprot id: F8G7S9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

573569:F7308 RS05355
gene id: 573569:F7308_RS05355
uniprot id: F8GC84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

573569:F7308 RS02050
gene id: 573569:F7308_RS02050
uniprot id: F8G9C0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

573569:F7308 RS08340
gene id: 573569:F7308_RS08340
uniprot id: F8G9J1
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

573569:F7308 RS03820
gene id: 573569:F7308_RS03820
uniprot id: F8GBC3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

573569:F7308 RS06545
gene id: 573569:F7308_RS06545
uniprot id: F8G7K6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

573569:F7308 RS02140
gene id: 573569:F7308_RS02140
uniprot id: F8G9D9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

573569:F7308 RS01200
gene id: 573569:F7308_RS01200
uniprot id: F8G8D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

573569:F7308 RS03080
gene id: 573569:F7308_RS03080
uniprot id: F8GAL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

573569:F7308 RS02775
gene id: 573569:F7308_RS02775
uniprot id: F8GA71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

573569:F7308 RS08995
gene id: 573569:F7308_RS08995
uniprot id: F8GAC7
names: Similarity
messages: Belongs to the threonine synthase family.

573569:F7308 RS07835
gene id: 573569:F7308_RS07835
uniprot id: F8G908
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

573569:F7308 RS08945
gene id: 573569:F7308_RS08945
uniprot id: F8GAB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573569:F7308 RS06840
gene id: 573569:F7308_RS06840
uniprot id: F8G7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

573569:F7308 RS03245
gene id: 573569:F7308_RS03245
uniprot id: F8GAP1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

573569:F7308 RS03565
gene id: 573569:F7308_RS03565
uniprot id: F8GB31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

573569:F7308 RS02030
gene id: 573569:F7308_RS02030
uniprot id: F8G9B6
names: Subcellular Location Annotation
messages: Membrane

573569:F7308 RS06115
gene id: 573569:F7308_RS06115
uniprot id: F8G740
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

573569:F7308 RS00645
gene id: 573569:F7308_RS00645
uniprot id: F8G7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane