573413:SPIRS RS09690
gene id: 573413:SPIRS_RS09690
uniprot id: E1R6M3
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

573413:SPIRS RS14590
gene id: 573413:SPIRS_RS14590
uniprot id: E1R3M1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

573413:SPIRS RS03700
gene id: 573413:SPIRS_RS03700
uniprot id: E1RBY6
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

573413:SPIRS RS05705
gene id: 573413:SPIRS_RS05705
uniprot id: E1R114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

573413:SPIRS RS18455
gene id: 573413:SPIRS_RS18455
uniprot id: E1R7N9
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

573413:SPIRS RS13245
gene id: 573413:SPIRS_RS13245
uniprot id: E1R4J2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS00405
gene id: 573413:SPIRS_RS00405
uniprot id: E1R899
names: Similarity
messages: Belongs to the band 7/mec-2 family.

573413:SPIRS RS00950
gene id: 573413:SPIRS_RS00950
uniprot id: E1R8K0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

573413:SPIRS RS04510
gene id: 573413:SPIRS_RS04510
uniprot id: E1RCE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS20735
gene id: 573413:SPIRS_RS20735
uniprot id: E1R9N0
names: Similarity
messages: Belongs to the Nth/MutY family.

573413:SPIRS RS02860
gene id: 573413:SPIRS_RS02860
uniprot id: E1RBH8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

573413:SPIRS RS17175
gene id: 573413:SPIRS_RS17175
uniprot id: E1R2D2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

573413:SPIRS RS10360
gene id: 573413:SPIRS_RS10360
uniprot id: E1R2Y6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS20745
gene id: 573413:SPIRS_RS20745
uniprot id: E1R9N2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS19850
gene id: 573413:SPIRS_RS19850
uniprot id: E1R955
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573413:SPIRS RS00930
gene id: 573413:SPIRS_RS00930
uniprot id: E1R8J6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

573413:SPIRS RS20755
gene id: 573413:SPIRS_RS20755
uniprot id: E1R9N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

573413:SPIRS RS14375
gene id: 573413:SPIRS_RS14375
uniprot id: E1R264
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

573413:SPIRS RS09680
gene id: 573413:SPIRS_RS09680
uniprot id: E1R6M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

573413:SPIRS RS15380
gene id: 573413:SPIRS_RS15380
uniprot id: E1R4R0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

573413:SPIRS RS15410
gene id: 573413:SPIRS_RS15410
uniprot id: E1R4R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS03895
gene id: 573413:SPIRS_RS03895
uniprot id: E1RC26
names: Similarity
messages: Belongs to the DapA family.

573413:SPIRS RS21420
gene id: 573413:SPIRS_RS21420
uniprot id: E1RA13
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

573413:SPIRS RS08215
gene id: 573413:SPIRS_RS08215
uniprot id: E1R5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS16770
gene id: 573413:SPIRS_RS16770
uniprot id: E1RAQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS20840
gene id: 573413:SPIRS_RS20840
uniprot id: E1R9Q1
names: Similarity
messages: Belongs to the BMP lipoprotein family.

573413:SPIRS RS10185
gene id: 573413:SPIRS_RS10185
uniprot id: E1R1J6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

573413:SPIRS RS11100
gene id: 573413:SPIRS_RS11100
uniprot id: E1R6Y8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

573413:SPIRS RS04840
gene id: 573413:SPIRS_RS04840
uniprot id: E1RCL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

573413:SPIRS RS12025
gene id: 573413:SPIRS_RS12025
uniprot id: E1R1X2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

573413:SPIRS RS10515
gene id: 573413:SPIRS_RS10515
uniprot id: E1R316
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

573413:SPIRS RS16130
gene id: 573413:SPIRS_RS16130
uniprot id: E1R5G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

573413:SPIRS RS07070
gene id: 573413:SPIRS_RS07070
uniprot id: E1R4A5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

573413:SPIRS RS21345
gene id: 573413:SPIRS_RS21345
uniprot id: E1R9Z8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS21990
gene id: 573413:SPIRS_RS21990
uniprot id: E1R3J5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

573413:SPIRS RS08530
gene id: 573413:SPIRS_RS08530
uniprot id: E1R649
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

573413:SPIRS RS08000
gene id: 573413:SPIRS_RS08000
uniprot id: E1R5U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

573413:SPIRS RS10260
gene id: 573413:SPIRS_RS10260
uniprot id: E1R1L1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

573413:SPIRS RS12820
gene id: 573413:SPIRS_RS12820
uniprot id: E1R4A9
names: Similarity
messages: Belongs to the citrate synthase family.

573413:SPIRS RS03740
gene id: 573413:SPIRS_RS03740
uniprot id: E1RBZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS20400
gene id: 573413:SPIRS_RS20400
uniprot id: E1R9G3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

573413:SPIRS RS21155
gene id: 573413:SPIRS_RS21155
uniprot id: E1R9W2
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS00055
gene id: 573413:SPIRS_RS00055
uniprot id: E1R6P0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

573413:SPIRS RS15375
gene id: 573413:SPIRS_RS15375
uniprot id: E1R4Q9
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

573413:SPIRS RS13130
gene id: 573413:SPIRS_RS13130
uniprot id: E1R4G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Periplasm
messages: Periplasmic flagellum
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.

573413:SPIRS RS13360
gene id: 573413:SPIRS_RS13360
uniprot id: E1R4L3
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS08290
gene id: 573413:SPIRS_RS08290
uniprot id: E1R602
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

573413:SPIRS RS18650
gene id: 573413:SPIRS_RS18650
uniprot id: E1R7S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

573413:SPIRS RS05630
gene id: 573413:SPIRS_RS05630
uniprot id: E1R100
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS03960
gene id: 573413:SPIRS_RS03960
uniprot id: E1RC39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS15755
gene id: 573413:SPIRS_RS15755
uniprot id: E1R4Y3
names: Caution
names: Function
names: Similarity
messages: Belongs to the GARS family.
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: In the C-terminal section; belongs to the GART family.
messages: In the central section; belongs to the AIR synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS00230
gene id: 573413:SPIRS_RS00230
uniprot id: E1R6S5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

573413:SPIRS RS16205
gene id: 573413:SPIRS_RS16205
uniprot id: E1R5I4
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

573413:SPIRS RS19225
gene id: 573413:SPIRS_RS19225
uniprot id: E1R844
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

573413:SPIRS RS18150
gene id: 573413:SPIRS_RS18150
uniprot id: E1R7I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS03455
gene id: 573413:SPIRS_RS03455
uniprot id: E1RBU1
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

573413:SPIRS RS16625
gene id: 573413:SPIRS_RS16625
uniprot id: E1RAM1
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

573413:SPIRS RS15190
gene id: 573413:SPIRS_RS15190
uniprot id: E1R3Y9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

573413:SPIRS RS11585
gene id: 573413:SPIRS_RS11585
uniprot id: E1R1N7
names: Similarity
messages: Belongs to the fabD family.

573413:SPIRS RS11605
gene id: 573413:SPIRS_RS11605
uniprot id: E1R1P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Monomer.

573413:SPIRS RS13085
gene id: 573413:SPIRS_RS13085
uniprot id: E1R4G0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

573413:SPIRS RS08360
gene id: 573413:SPIRS_RS08360
uniprot id: E1R616
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

573413:SPIRS RS04335
gene id: 573413:SPIRS_RS04335
uniprot id: E1RCB4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573413:SPIRS RS07450
gene id: 573413:SPIRS_RS07450
uniprot id: E1R568
names: Similarity
messages: Belongs to the phosphohexose mutase family.

573413:SPIRS RS07490
gene id: 573413:SPIRS_RS07490
uniprot id: E1R576
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS09170
gene id: 573413:SPIRS_RS09170
uniprot id: E1R6C0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

573413:SPIRS RS19380
gene id: 573413:SPIRS_RS19380
uniprot id: E1R876
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

573413:SPIRS RS03555
gene id: 573413:SPIRS_RS03555
uniprot id: E1RBV7
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

573413:SPIRS RS09455
gene id: 573413:SPIRS_RS09455
uniprot id: E1R6H5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

573413:SPIRS RS17980
gene id: 573413:SPIRS_RS17980
uniprot id: E1R7E7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

573413:SPIRS RS15845
gene id: 573413:SPIRS_RS15845
uniprot id: E1R5B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm

573413:SPIRS RS15970
gene id: 573413:SPIRS_RS15970
uniprot id: E1R5D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

573413:SPIRS RS10280
gene id: 573413:SPIRS_RS10280
uniprot id: E1R1L5
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

573413:SPIRS RS20585
gene id: 573413:SPIRS_RS20585
uniprot id: E1R9K0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

573413:SPIRS RS21500
gene id: 573413:SPIRS_RS21500
uniprot id: E1RA28
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

573413:SPIRS RS00220
gene id: 573413:SPIRS_RS00220
uniprot id: E1R6S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS05495
gene id: 573413:SPIRS_RS05495
uniprot id: E1R0X3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

573413:SPIRS RS09135
gene id: 573413:SPIRS_RS09135
uniprot id: E1R6B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

573413:SPIRS RS02995
gene id: 573413:SPIRS_RS02995
uniprot id: E1RBK6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

573413:SPIRS RS15320
gene id: 573413:SPIRS_RS15320
uniprot id: E1R4P8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

573413:SPIRS RS10485
gene id: 573413:SPIRS_RS10485
uniprot id: E1R311
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS04105
gene id: 573413:SPIRS_RS04105
uniprot id: E1RC68
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

573413:SPIRS RS06455
gene id: 573413:SPIRS_RS06455
uniprot id: E1R2X8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS08210
gene id: 573413:SPIRS_RS08210
uniprot id: E1R5Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS21870
gene id: 573413:SPIRS_RS21870
uniprot id: E1RAL2
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS11150
gene id: 573413:SPIRS_RS11150
uniprot id: E1R6Z8
names: Subcellular Location Annotation
messages: Cytoplasm

573413:SPIRS RS00015
gene id: 573413:SPIRS_RS00015
uniprot id: E1R6N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

573413:SPIRS RS06835
gene id: 573413:SPIRS_RS06835
uniprot id: E1R458
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS05955
gene id: 573413:SPIRS_RS05955
uniprot id: E1R2N0
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS00890
gene id: 573413:SPIRS_RS00890
uniprot id: E1R8I9
names: Similarity
messages: Belongs to the CobT family.

573413:SPIRS RS08420
gene id: 573413:SPIRS_RS08420
uniprot id: E1R627
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS18210
gene id: 573413:SPIRS_RS18210
uniprot id: E1R7J2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

573413:SPIRS RS10845
gene id: 573413:SPIRS_RS10845
uniprot id: E1R380
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS02420
gene id: 573413:SPIRS_RS02420
uniprot id: E1RB94
names: Subcellular Location Annotation
messages: Cell inner membrane

573413:SPIRS RS16025
gene id: 573413:SPIRS_RS16025
uniprot id: E1R5E8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

573413:SPIRS RS16285
gene id: 573413:SPIRS_RS16285
uniprot id: E1R5J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

573413:SPIRS RS00795
gene id: 573413:SPIRS_RS00795
uniprot id: E1R8H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

573413:SPIRS RS01320
gene id: 573413:SPIRS_RS01320
uniprot id: E1RAC6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS17020
gene id: 573413:SPIRS_RS17020
uniprot id: E1R2A3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

573413:SPIRS RS11775
gene id: 573413:SPIRS_RS11775
uniprot id: E1R1S3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

573413:SPIRS RS10255
gene id: 573413:SPIRS_RS10255
uniprot id: E1R1L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

573413:SPIRS RS15765
gene id: 573413:SPIRS_RS15765
uniprot id: E1R4Y5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

573413:SPIRS RS18275
gene id: 573413:SPIRS_RS18275
uniprot id: E1R7K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

573413:SPIRS RS21150
gene id: 573413:SPIRS_RS21150
uniprot id: E1R9W1
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS17850
gene id: 573413:SPIRS_RS17850
uniprot id: E1R7C1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

573413:SPIRS RS19275
gene id: 573413:SPIRS_RS19275
uniprot id: E1R855
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS15870
gene id: 573413:SPIRS_RS15870
uniprot id: E1R5B6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

573413:SPIRS RS15535
gene id: 573413:SPIRS_RS15535
uniprot id: E1R4T9
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS18575
gene id: 573413:SPIRS_RS18575
uniprot id: E1R7R4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573413:SPIRS RS17455
gene id: 573413:SPIRS_RS17455
uniprot id: E1R2I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

573413:SPIRS RS18255
gene id: 573413:SPIRS_RS18255
uniprot id: E1R7K0
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

573413:SPIRS RS15770
gene id: 573413:SPIRS_RS15770
uniprot id: E1R4Y6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

573413:SPIRS RS14520
gene id: 573413:SPIRS_RS14520
uniprot id: E1R293
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

573413:SPIRS RS16920
gene id: 573413:SPIRS_RS16920
uniprot id: E1RAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

573413:SPIRS RS00680
gene id: 573413:SPIRS_RS00680
uniprot id: E1R8E7
names: Similarity
messages: Belongs to the RutC family.

573413:SPIRS RS17110
gene id: 573413:SPIRS_RS17110
uniprot id: E1R2C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573413:SPIRS RS04795
gene id: 573413:SPIRS_RS04795
uniprot id: E1RCK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

573413:SPIRS RS08475
gene id: 573413:SPIRS_RS08475
uniprot id: E1R638
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS00410
gene id: 573413:SPIRS_RS00410
uniprot id: E1R8A0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

573413:SPIRS RS03755
gene id: 573413:SPIRS_RS03755
uniprot id: E1RBZ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS13300
gene id: 573413:SPIRS_RS13300
uniprot id: E1R4K1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

573413:SPIRS RS09855
gene id: 573413:SPIRS_RS09855
uniprot id: E1R1D3
names: Similarity
messages: Belongs to the ketopantoate reductase family.

573413:SPIRS RS08260
gene id: 573413:SPIRS_RS08260
uniprot id: E1R5Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

573413:SPIRS RS09435
gene id: 573413:SPIRS_RS09435
uniprot id: E1R6H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

573413:SPIRS RS00225
gene id: 573413:SPIRS_RS00225
uniprot id: E1R6S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS16430
gene id: 573413:SPIRS_RS16430
uniprot id: E1RAI5
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

573413:SPIRS RS06585
gene id: 573413:SPIRS_RS06585
uniprot id: E1R408
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

573413:SPIRS RS01195
gene id: 573413:SPIRS_RS01195
uniprot id: E1RAA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

573413:SPIRS RS04815
gene id: 573413:SPIRS_RS04815
uniprot id: E1RCK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

573413:SPIRS RS11515
gene id: 573413:SPIRS_RS11515
uniprot id: E1R772
names: Similarity
messages: Belongs to the CapA family.

573413:SPIRS RS07840
gene id: 573413:SPIRS_RS07840
uniprot id: E1R5R1
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS12005
gene id: 573413:SPIRS_RS12005
uniprot id: E1R1W8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

573413:SPIRS RS00270
gene id: 573413:SPIRS_RS00270
uniprot id: E1R6T3
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS08660
gene id: 573413:SPIRS_RS08660
uniprot id: E1R675
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

573413:SPIRS RS09090
gene id: 573413:SPIRS_RS09090
uniprot id: E1R1A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS02500
gene id: 573413:SPIRS_RS02500
uniprot id: E1RBB0
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS14535
gene id: 573413:SPIRS_RS14535
uniprot id: E1R296
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

573413:SPIRS RS06725
gene id: 573413:SPIRS_RS06725
uniprot id: E1R436
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

573413:SPIRS RS05470
gene id: 573413:SPIRS_RS05470
uniprot id: E1R0W8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

573413:SPIRS RS01375
gene id: 573413:SPIRS_RS01375
uniprot id: E1RAD7
names: Similarity
messages: Belongs to the IMPACT family.

573413:SPIRS RS19490
gene id: 573413:SPIRS_RS19490
uniprot id: E1R8Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS04545
gene id: 573413:SPIRS_RS04545
uniprot id: E1RCF3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573413:SPIRS RS15430
gene id: 573413:SPIRS_RS15430
uniprot id: E1R4R9
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS16650
gene id: 573413:SPIRS_RS16650
uniprot id: E1RAM6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573413:SPIRS RS17395
gene id: 573413:SPIRS_RS17395
uniprot id: E1R2H6
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS07750
gene id: 573413:SPIRS_RS07750
uniprot id: E1R5P3
names: Similarity
messages: Belongs to the universal stress protein A family.

573413:SPIRS RS21475
gene id: 573413:SPIRS_RS21475
uniprot id: E1RA24
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS13970
gene id: 573413:SPIRS_RS13970
uniprot id: E1R8W4
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS21220
gene id: 573413:SPIRS_RS21220
uniprot id: E1R9X5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

573413:SPIRS RS20860
gene id: 573413:SPIRS_RS20860
uniprot id: E1R9Q5
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

573413:SPIRS RS05890
gene id: 573413:SPIRS_RS05890
uniprot id: E1R150
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS14605
gene id: 573413:SPIRS_RS14605
uniprot id: E1R3M4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

573413:SPIRS RS05390
gene id: 573413:SPIRS_RS05390
uniprot id: E1R0V4
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

573413:SPIRS RS07970
gene id: 573413:SPIRS_RS07970
uniprot id: E1R5T7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

573413:SPIRS RS05415
gene id: 573413:SPIRS_RS05415
uniprot id: E1R0V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

573413:SPIRS RS07880
gene id: 573413:SPIRS_RS07880
uniprot id: E1R5R9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

573413:SPIRS RS18060
gene id: 573413:SPIRS_RS18060
uniprot id: E1R7G2
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS15670
gene id: 573413:SPIRS_RS15670
uniprot id: E1R4W6
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

573413:SPIRS RS03685
gene id: 573413:SPIRS_RS03685
uniprot id: E1RBY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS18625
gene id: 573413:SPIRS_RS18625
uniprot id: E1R7S4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

573413:SPIRS RS03445
gene id: 573413:SPIRS_RS03445
uniprot id: E1RBT9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

573413:SPIRS RS00145
gene id: 573413:SPIRS_RS00145
uniprot id: E1R6Q8
names: Similarity
messages: Belongs to the creatininase superfamily.

573413:SPIRS RS05030
gene id: 573413:SPIRS_RS05030
uniprot id: E1RCQ0
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

573413:SPIRS RS06845
gene id: 573413:SPIRS_RS06845
uniprot id: E1R460
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

573413:SPIRS RS08130
gene id: 573413:SPIRS_RS08130
uniprot id: E1R5X0
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

573413:SPIRS RS17505
gene id: 573413:SPIRS_RS17505
uniprot id: E1R2J7
names: Similarity
messages: Belongs to the UPF0166 family.

573413:SPIRS RS09665
gene id: 573413:SPIRS_RS09665
uniprot id: E1R6L8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

573413:SPIRS RS05320
gene id: 573413:SPIRS_RS05320
uniprot id: E1R0T9
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS18770
gene id: 573413:SPIRS_RS18770
uniprot id: E1R7V3
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS13415
gene id: 573413:SPIRS_RS13415
uniprot id: E1R4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS07300
gene id: 573413:SPIRS_RS07300
uniprot id: E1R538
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

573413:SPIRS RS16255
gene id: 573413:SPIRS_RS16255
uniprot id: E1R5J3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

573413:SPIRS RS17985
gene id: 573413:SPIRS_RS17985
uniprot id: E1R7E8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

573413:SPIRS RS09910
gene id: 573413:SPIRS_RS09910
uniprot id: E1R1E3
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

573413:SPIRS RS17595
gene id: 573413:SPIRS_RS17595
uniprot id: E1R2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

573413:SPIRS RS21570
gene id: 573413:SPIRS_RS21570
uniprot id: E1RA42
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

573413:SPIRS RS14825
gene id: 573413:SPIRS_RS14825
uniprot id: E1R3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

573413:SPIRS RS20885
gene id: 573413:SPIRS_RS20885
uniprot id: E1R9R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

573413:SPIRS RS19075
gene id: 573413:SPIRS_RS19075
uniprot id: E1R814
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS09915
gene id: 573413:SPIRS_RS09915
uniprot id: E1R1E4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

573413:SPIRS RS02470
gene id: 573413:SPIRS_RS02470
uniprot id: E1RBA4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573413:SPIRS RS04025
gene id: 573413:SPIRS_RS04025
uniprot id: E1RC52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS08125
gene id: 573413:SPIRS_RS08125
uniprot id: E1R5W9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS12410
gene id: 573413:SPIRS_RS12410
uniprot id: E1R3E0
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

573413:SPIRS RS18660
gene id: 573413:SPIRS_RS18660
uniprot id: E1R7T1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

573413:SPIRS RS16970
gene id: 573413:SPIRS_RS16970
uniprot id: E1RAT7
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

573413:SPIRS RS04955
gene id: 573413:SPIRS_RS04955
uniprot id: E1RCN5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

573413:SPIRS RS18385
gene id: 573413:SPIRS_RS18385
uniprot id: E1R7M5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

573413:SPIRS RS16735
gene id: 573413:SPIRS_RS16735
uniprot id: E1RAP3
names: Similarity
messages: Belongs to the peptidase C69 family.

573413:SPIRS RS15690
gene id: 573413:SPIRS_RS15690
uniprot id: E1R4X0
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

573413:SPIRS RS20195
gene id: 573413:SPIRS_RS20195
uniprot id: E1R9C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

573413:SPIRS RS05020
gene id: 573413:SPIRS_RS05020
uniprot id: E1RCP8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

573413:SPIRS RS00425
gene id: 573413:SPIRS_RS00425
uniprot id: E1R8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

573413:SPIRS RS12310
gene id: 573413:SPIRS_RS12310
uniprot id: E1R3C0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

573413:SPIRS RS18380
gene id: 573413:SPIRS_RS18380
uniprot id: E1R7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

573413:SPIRS RS21120
gene id: 573413:SPIRS_RS21120
uniprot id: E1R9V5
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS19180
gene id: 573413:SPIRS_RS19180
uniprot id: E1R835
names: Similarity
messages: Belongs to the FGGY kinase family.

573413:SPIRS RS08965
gene id: 573413:SPIRS_RS08965
uniprot id: E1R180
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS15915
gene id: 573413:SPIRS_RS15915
uniprot id: E1R5C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS05050
gene id: 573413:SPIRS_RS05050
uniprot id: E1RCQ4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

573413:SPIRS RS14705
gene id: 573413:SPIRS_RS14705
uniprot id: E1R3P4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

573413:SPIRS RS06700
gene id: 573413:SPIRS_RS06700
uniprot id: E1R431
names: Similarity
messages: Belongs to the YggT family.

573413:SPIRS RS07140
gene id: 573413:SPIRS_RS07140
uniprot id: E1R506
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS09050
gene id: 573413:SPIRS_RS09050
uniprot id: E1R196
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

573413:SPIRS RS08500
gene id: 573413:SPIRS_RS08500
uniprot id: E1R643
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS20685
gene id: 573413:SPIRS_RS20685
uniprot id: E1R9M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

573413:SPIRS RS10290
gene id: 573413:SPIRS_RS10290
uniprot id: E1R1L7
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS15130
gene id: 573413:SPIRS_RS15130
uniprot id: E1R3X7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573413:SPIRS RS06595
gene id: 573413:SPIRS_RS06595
uniprot id: E1R410
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

573413:SPIRS RS10475
gene id: 573413:SPIRS_RS10475
uniprot id: E1R309
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

573413:SPIRS RS07380
gene id: 573413:SPIRS_RS07380
uniprot id: E1R554
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

573413:SPIRS RS02785
gene id: 573413:SPIRS_RS02785
uniprot id: E1RBG3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

573413:SPIRS RS03385
gene id: 573413:SPIRS_RS03385
uniprot id: E1RBS8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

573413:SPIRS RS05360
gene id: 573413:SPIRS_RS05360
uniprot id: E1R0U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS04850
gene id: 573413:SPIRS_RS04850
uniprot id: E1RCL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

573413:SPIRS RS11615
gene id: 573413:SPIRS_RS11615
uniprot id: E1R1P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS21470
gene id: 573413:SPIRS_RS21470
uniprot id: E1RA23
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS17060
gene id: 573413:SPIRS_RS17060
uniprot id: E1R2B2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

573413:SPIRS RS10890
gene id: 573413:SPIRS_RS10890
uniprot id: E1R389
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS02615
gene id: 573413:SPIRS_RS02615
uniprot id: E1RBD1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573413:SPIRS RS09130
gene id: 573413:SPIRS_RS09130
uniprot id: E1R6B2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

573413:SPIRS RS03780
gene id: 573413:SPIRS_RS03780
uniprot id: E1RC02
names: Similarity
messages: Belongs to the creatininase superfamily.

573413:SPIRS RS16505
gene id: 573413:SPIRS_RS16505
uniprot id: E1RAJ9
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS02295
gene id: 573413:SPIRS_RS02295
uniprot id: E1RB69
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

573413:SPIRS RS13165
gene id: 573413:SPIRS_RS13165
uniprot id: E1R4H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

573413:SPIRS RS11835
gene id: 573413:SPIRS_RS11835
uniprot id: E1R1T4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

573413:SPIRS RS21645
gene id: 573413:SPIRS_RS21645
uniprot id: E1RA57
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

573413:SPIRS RS01340
gene id: 573413:SPIRS_RS01340
uniprot id: E1RAD0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS13680
gene id: 573413:SPIRS_RS13680
uniprot id: E1R8Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

573413:SPIRS RS12190
gene id: 573413:SPIRS_RS12190
uniprot id: E1R396
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS15820
gene id: 573413:SPIRS_RS15820
uniprot id: E1R5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

573413:SPIRS RS14610
gene id: 573413:SPIRS_RS14610
uniprot id: E1R3M5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS01730
gene id: 573413:SPIRS_RS01730
uniprot id: E1RAW8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

573413:SPIRS RS12455
gene id: 573413:SPIRS_RS12455
uniprot id: E1R3E9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

573413:SPIRS RS04835
gene id: 573413:SPIRS_RS04835
uniprot id: E1RCK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

573413:SPIRS RS06235
gene id: 573413:SPIRS_RS06235
uniprot id: E1R2T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

573413:SPIRS RS13030
gene id: 573413:SPIRS_RS13030
uniprot id: E1R4E9
names: Similarity
messages: Belongs to the hyi family.

573413:SPIRS RS17450
gene id: 573413:SPIRS_RS17450
uniprot id: E1R2I6
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS18680
gene id: 573413:SPIRS_RS18680
uniprot id: E1R7T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

573413:SPIRS RS01360
gene id: 573413:SPIRS_RS01360
uniprot id: E1RAD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

573413:SPIRS RS05930
gene id: 573413:SPIRS_RS05930
uniprot id: E1R2M5
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

573413:SPIRS RS09195
gene id: 573413:SPIRS_RS09195
uniprot id: E1R6C4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

573413:SPIRS RS14350
gene id: 573413:SPIRS_RS14350
uniprot id: E1R259
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS07410
gene id: 573413:SPIRS_RS07410
uniprot id: E1R560
names: Function
names: Similarity
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.

573413:SPIRS RS16820
gene id: 573413:SPIRS_RS16820
uniprot id: E1RAR0
names: Similarity
messages: Belongs to the citrate synthase family.

573413:SPIRS RS01435
gene id: 573413:SPIRS_RS01435
uniprot id: E1RAE9
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS02555
gene id: 573413:SPIRS_RS02555
uniprot id: E1RBC1
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS16460
gene id: 573413:SPIRS_RS16460
uniprot id: E1RAJ0
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS05865
gene id: 573413:SPIRS_RS05865
uniprot id: E1R145
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS02800
gene id: 573413:SPIRS_RS02800
uniprot id: E1RBG6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

573413:SPIRS RS08045
gene id: 573413:SPIRS_RS08045
uniprot id: E1R5V2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

573413:SPIRS RS12415
gene id: 573413:SPIRS_RS12415
uniprot id: E1R3E1
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

573413:SPIRS RS21460
gene id: 573413:SPIRS_RS21460
uniprot id: E1RA21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS03280
gene id: 573413:SPIRS_RS03280
uniprot id: E1RBQ9
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

573413:SPIRS RS08400
gene id: 573413:SPIRS_RS08400
uniprot id: E1R623
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

573413:SPIRS RS00855
gene id: 573413:SPIRS_RS00855
uniprot id: E1R8I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

573413:SPIRS RS16715
gene id: 573413:SPIRS_RS16715
uniprot id: E1RAN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS20075
gene id: 573413:SPIRS_RS20075
uniprot id: E1R9A0
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

573413:SPIRS RS06515
gene id: 573413:SPIRS_RS06515
uniprot id: E1R3Z9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

573413:SPIRS RS06345
gene id: 573413:SPIRS_RS06345
uniprot id: E1R2V6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

573413:SPIRS RS02220
gene id: 573413:SPIRS_RS02220
uniprot id: E1RB55
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

573413:SPIRS RS15315
gene id: 573413:SPIRS_RS15315
uniprot id: E1R4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS04935
gene id: 573413:SPIRS_RS04935
uniprot id: E1RCN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

573413:SPIRS RS06315
gene id: 573413:SPIRS_RS06315
uniprot id: E1R2V0
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

573413:SPIRS RS14995
gene id: 573413:SPIRS_RS14995
uniprot id: E1R3V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

573413:SPIRS RS13175
gene id: 573413:SPIRS_RS13175
uniprot id: E1R4H8
names: Function
names: Subcellular Location Annotation
messages: Component of the core of the flagella.
messages: Periplasmic flagellum

573413:SPIRS RS17770
gene id: 573413:SPIRS_RS17770
uniprot id: E1R7A5
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

573413:SPIRS RS06035
gene id: 573413:SPIRS_RS06035
uniprot id: E1R2P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS17425
gene id: 573413:SPIRS_RS17425
uniprot id: E1R2I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS00525
gene id: 573413:SPIRS_RS00525
uniprot id: E1R8B8
names: Similarity
messages: Belongs to the hemerythrin family.

573413:SPIRS RS14560
gene id: 573413:SPIRS_RS14560
uniprot id: E1R2A1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

573413:SPIRS RS04205
gene id: 573413:SPIRS_RS04205
uniprot id: E1RC89
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS00985
gene id: 573413:SPIRS_RS00985
uniprot id: E1R8K6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

573413:SPIRS RS06440
gene id: 573413:SPIRS_RS06440
uniprot id: E1R2X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS14540
gene id: 573413:SPIRS_RS14540
uniprot id: E1R297
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

573413:SPIRS RS18130
gene id: 573413:SPIRS_RS18130
uniprot id: E1R7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS17370
gene id: 573413:SPIRS_RS17370
uniprot id: E1R2H1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

573413:SPIRS RS08325
gene id: 573413:SPIRS_RS08325
uniprot id: E1R609
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

573413:SPIRS RS10805
gene id: 573413:SPIRS_RS10805
uniprot id: E1R372
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

573413:SPIRS RS00935
gene id: 573413:SPIRS_RS00935
uniprot id: E1R8J7
names: Similarity
messages: Belongs to the CobH/CbiC family.

573413:SPIRS RS06275
gene id: 573413:SPIRS_RS06275
uniprot id: E1R2U2
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS08690
gene id: 573413:SPIRS_RS08690
uniprot id: E1R681
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS16935
gene id: 573413:SPIRS_RS16935
uniprot id: E1RAT1
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

573413:SPIRS RS17815
gene id: 573413:SPIRS_RS17815
uniprot id: E1R7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS21355
gene id: 573413:SPIRS_RS21355
uniprot id: E1RA00
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

573413:SPIRS RS05925
gene id: 573413:SPIRS_RS05925
uniprot id: E1R2M4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

573413:SPIRS RS16745
gene id: 573413:SPIRS_RS16745
uniprot id: E1RAP5
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS10715
gene id: 573413:SPIRS_RS10715
uniprot id: E1R354
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

573413:SPIRS RS07525
gene id: 573413:SPIRS_RS07525
uniprot id: E1R583
names: Similarity
messages: Belongs to the TrpR family.

573413:SPIRS RS11315
gene id: 573413:SPIRS_RS11315
uniprot id: E1R732
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

573413:SPIRS RS12095
gene id: 573413:SPIRS_RS12095
uniprot id: E1R1Y2
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

573413:SPIRS RS10720
gene id: 573413:SPIRS_RS10720
uniprot id: E1R355
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS21090
gene id: 573413:SPIRS_RS21090
uniprot id: E1R9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS13890
gene id: 573413:SPIRS_RS13890
uniprot id: E1R8U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

573413:SPIRS RS01365
gene id: 573413:SPIRS_RS01365
uniprot id: E1RAD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

573413:SPIRS RS15565
gene id: 573413:SPIRS_RS15565
uniprot id: E1R4U6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

573413:SPIRS RS15305
gene id: 573413:SPIRS_RS15305
uniprot id: E1R4P5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

573413:SPIRS RS12855
gene id: 573413:SPIRS_RS12855
uniprot id: E1R4B6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

573413:SPIRS RS17485
gene id: 573413:SPIRS_RS17485
uniprot id: E1R2J3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

573413:SPIRS RS05580
gene id: 573413:SPIRS_RS05580
uniprot id: E1R0Z0
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

573413:SPIRS RS03030
gene id: 573413:SPIRS_RS03030
uniprot id: E1RBL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

573413:SPIRS RS04645
gene id: 573413:SPIRS_RS04645
uniprot id: E1RCH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS01505
gene id: 573413:SPIRS_RS01505
uniprot id: E1RAG3
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS13955
gene id: 573413:SPIRS_RS13955
uniprot id: E1R8W1
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

573413:SPIRS RS09635
gene id: 573413:SPIRS_RS09635
uniprot id: E1R6L2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS20750
gene id: 573413:SPIRS_RS20750
uniprot id: E1R9N3
names: Function
names: Similarity
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

573413:SPIRS RS19840
gene id: 573413:SPIRS_RS19840
uniprot id: E1R953
names: Similarity
messages: Belongs to the phosphopentomutase family.

573413:SPIRS RS17855
gene id: 573413:SPIRS_RS17855
uniprot id: E1R7C2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS04985
gene id: 573413:SPIRS_RS04985
uniprot id: E1RCP1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

573413:SPIRS RS11265
gene id: 573413:SPIRS_RS11265
uniprot id: E1R721
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

573413:SPIRS RS17025
gene id: 573413:SPIRS_RS17025
uniprot id: E1R2A4
names: Similarity
messages: Belongs to the YoeB family.

573413:SPIRS RS16015
gene id: 573413:SPIRS_RS16015
uniprot id: E1R5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS04905
gene id: 573413:SPIRS_RS04905
uniprot id: E1RCM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

573413:SPIRS RS19160
gene id: 573413:SPIRS_RS19160
uniprot id: E1R831
names: Similarity
messages: Belongs to the DEAD box helicase family.

573413:SPIRS RS14530
gene id: 573413:SPIRS_RS14530
uniprot id: E1R295
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

573413:SPIRS RS05310
gene id: 573413:SPIRS_RS05310
uniprot id: E1R0T7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

573413:SPIRS RS00675
gene id: 573413:SPIRS_RS00675
uniprot id: E1R8E6
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

573413:SPIRS RS12200
gene id: 573413:SPIRS_RS12200
uniprot id: E1R398
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

573413:SPIRS RS06590
gene id: 573413:SPIRS_RS06590
uniprot id: E1R409
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

573413:SPIRS RS10245
gene id: 573413:SPIRS_RS10245
uniprot id: E1R1K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

573413:SPIRS RS17440
gene id: 573413:SPIRS_RS17440
uniprot id: E1R2I4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

573413:SPIRS RS21630
gene id: 573413:SPIRS_RS21630
uniprot id: E1RA54
names: Similarity
messages: Belongs to the ParB family.

573413:SPIRS RS06815
gene id: 573413:SPIRS_RS06815
uniprot id: E1R454
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

573413:SPIRS RS15880
gene id: 573413:SPIRS_RS15880
uniprot id: E1R5B8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

573413:SPIRS RS10785
gene id: 573413:SPIRS_RS10785
uniprot id: E1R368
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

573413:SPIRS RS01675
gene id: 573413:SPIRS_RS01675
uniprot id: E1RAV7
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

573413:SPIRS RS04825
gene id: 573413:SPIRS_RS04825
uniprot id: E1RCK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

573413:SPIRS RS08355
gene id: 573413:SPIRS_RS08355
uniprot id: E1R615
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

573413:SPIRS RS05870
gene id: 573413:SPIRS_RS05870
uniprot id: E1R146
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS14635
gene id: 573413:SPIRS_RS14635
uniprot id: E1R3N0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

573413:SPIRS RS09480
gene id: 573413:SPIRS_RS09480
uniprot id: E1R6I0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

573413:SPIRS RS18220
gene id: 573413:SPIRS_RS18220
uniprot id: E1R7J4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

573413:SPIRS RS04500
gene id: 573413:SPIRS_RS04500
uniprot id: E1RCE4
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

573413:SPIRS RS19005
gene id: 573413:SPIRS_RS19005
uniprot id: E1R801
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

573413:SPIRS RS16305
gene id: 573413:SPIRS_RS16305
uniprot id: E1R5J9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS13465
gene id: 573413:SPIRS_RS13465
uniprot id: E1R8L6
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

573413:SPIRS RS02460
gene id: 573413:SPIRS_RS02460
uniprot id: E1RBA2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

573413:SPIRS RS00820
gene id: 573413:SPIRS_RS00820
uniprot id: E1R8H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS08010
gene id: 573413:SPIRS_RS08010
uniprot id: E1R5U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

573413:SPIRS RS07065
gene id: 573413:SPIRS_RS07065
uniprot id: E1R4A4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

573413:SPIRS RS15360
gene id: 573413:SPIRS_RS15360
uniprot id: E1R4Q5
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS15460
gene id: 573413:SPIRS_RS15460
uniprot id: E1R4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS13445
gene id: 573413:SPIRS_RS13445
uniprot id: E1R8L2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

573413:SPIRS RS08315
gene id: 573413:SPIRS_RS08315
uniprot id: E1R607
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS12255
gene id: 573413:SPIRS_RS12255
uniprot id: E1R3A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

573413:SPIRS RS16145
gene id: 573413:SPIRS_RS16145
uniprot id: E1R5H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

573413:SPIRS RS12835
gene id: 573413:SPIRS_RS12835
uniprot id: E1R4B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

573413:SPIRS RS15060
gene id: 573413:SPIRS_RS15060
uniprot id: E1R3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

573413:SPIRS RS10435
gene id: 573413:SPIRS_RS10435
uniprot id: E1R301
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS05790
gene id: 573413:SPIRS_RS05790
uniprot id: E1R131
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

573413:SPIRS RS04470
gene id: 573413:SPIRS_RS04470
uniprot id: E1RCD8
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

573413:SPIRS RS17400
gene id: 573413:SPIRS_RS17400
uniprot id: E1R2H7
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

573413:SPIRS RS18620
gene id: 573413:SPIRS_RS18620
uniprot id: E1R7S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

573413:SPIRS RS17925
gene id: 573413:SPIRS_RS17925
uniprot id: E1R7D6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

573413:SPIRS RS08005
gene id: 573413:SPIRS_RS08005
uniprot id: E1R5U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

573413:SPIRS RS15900
gene id: 573413:SPIRS_RS15900
uniprot id: E1R5C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS04805
gene id: 573413:SPIRS_RS04805
uniprot id: E1RCK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

573413:SPIRS RS05155
gene id: 573413:SPIRS_RS05155
uniprot id: E1RCS5
names: Similarity
messages: Belongs to the carbamate kinase family.

573413:SPIRS RS04145
gene id: 573413:SPIRS_RS04145
uniprot id: E1RC76
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS12090
gene id: 573413:SPIRS_RS12090
uniprot id: E1R1Y1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

573413:SPIRS RS06150
gene id: 573413:SPIRS_RS06150
uniprot id: E1R2R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS12000
gene id: 573413:SPIRS_RS12000
uniprot id: E1R1W7
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

573413:SPIRS RS10575
gene id: 573413:SPIRS_RS10575
uniprot id: E1R326
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS05145
gene id: 573413:SPIRS_RS05145
uniprot id: E1RCS3
names: Similarity
messages: Belongs to the RutC family.

573413:SPIRS RS02830
gene id: 573413:SPIRS_RS02830
uniprot id: E1RBH2
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

573413:SPIRS RS02445
gene id: 573413:SPIRS_RS02445
uniprot id: E1RB99
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

573413:SPIRS RS04695
gene id: 573413:SPIRS_RS04695
uniprot id: E1RCI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

573413:SPIRS RS15175
gene id: 573413:SPIRS_RS15175
uniprot id: E1R3Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

573413:SPIRS RS18495
gene id: 573413:SPIRS_RS18495
uniprot id: E1R7P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

573413:SPIRS RS11395
gene id: 573413:SPIRS_RS11395
uniprot id: E1R748
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS04265
gene id: 573413:SPIRS_RS04265
uniprot id: E1RCA0
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS12350
gene id: 573413:SPIRS_RS12350
uniprot id: E1R3C8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

573413:SPIRS RS09150
gene id: 573413:SPIRS_RS09150
uniprot id: E1R6B6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

573413:SPIRS RS13180
gene id: 573413:SPIRS_RS13180
uniprot id: E1R4H9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

573413:SPIRS RS02795
gene id: 573413:SPIRS_RS02795
uniprot id: E1RBG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS01850
gene id: 573413:SPIRS_RS01850
uniprot id: E1RAZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573413:SPIRS RS15170
gene id: 573413:SPIRS_RS15170
uniprot id: E1R3Y5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

573413:SPIRS RS01180
gene id: 573413:SPIRS_RS01180
uniprot id: E1RA99
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573413:SPIRS RS13990
gene id: 573413:SPIRS_RS13990
uniprot id: E1R8W8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

573413:SPIRS RS10175
gene id: 573413:SPIRS_RS10175
uniprot id: E1R1J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

573413:SPIRS RS07355
gene id: 573413:SPIRS_RS07355
uniprot id: E1R549
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

573413:SPIRS RS09185
gene id: 573413:SPIRS_RS09185
uniprot id: E1R6C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

573413:SPIRS RS12270
gene id: 573413:SPIRS_RS12270
uniprot id: E1R3B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

573413:SPIRS RS15225
gene id: 573413:SPIRS_RS15225
uniprot id: E1R4M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

573413:SPIRS RS19655
gene id: 573413:SPIRS_RS19655
uniprot id: E1R916
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

573413:SPIRS RS12450
gene id: 573413:SPIRS_RS12450
uniprot id: E1R3E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

573413:SPIRS RS18790
gene id: 573413:SPIRS_RS18790
uniprot id: E1R7V8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS20080
gene id: 573413:SPIRS_RS20080
uniprot id: E1R9A1
names: Similarity
messages: Belongs to the hexokinase family.

573413:SPIRS RS17630
gene id: 573413:SPIRS_RS17630
uniprot id: E1R777
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS04945
gene id: 573413:SPIRS_RS04945
uniprot id: E1RCN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

573413:SPIRS RS02440
gene id: 573413:SPIRS_RS02440
uniprot id: E1RB98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS08910
gene id: 573413:SPIRS_RS08910
uniprot id: E1R169
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

573413:SPIRS RS14115
gene id: 573413:SPIRS_RS14115
uniprot id: E1R210
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

573413:SPIRS RS16810
gene id: 573413:SPIRS_RS16810
uniprot id: E1RAQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS06785
gene id: 573413:SPIRS_RS06785
uniprot id: E1R448
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

573413:SPIRS RS03025
gene id: 573413:SPIRS_RS03025
uniprot id: E1RBL1
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS12100
gene id: 573413:SPIRS_RS12100
uniprot id: E1R1Y3
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

573413:SPIRS RS13255
gene id: 573413:SPIRS_RS13255
uniprot id: E1R4J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

573413:SPIRS RS18740
gene id: 573413:SPIRS_RS18740
uniprot id: E1R7U7
names: Similarity
messages: Belongs to the thioredoxin family.

573413:SPIRS RS13490
gene id: 573413:SPIRS_RS13490
uniprot id: E1R8M1
names: Similarity
messages: Belongs to the BMP lipoprotein family.

573413:SPIRS RS07905
gene id: 573413:SPIRS_RS07905
uniprot id: E1R5S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

573413:SPIRS RS11105
gene id: 573413:SPIRS_RS11105
uniprot id: E1R6Y9
names: Similarity
messages: Belongs to the YoeB family.

573413:SPIRS RS09550
gene id: 573413:SPIRS_RS09550
uniprot id: E1R6J5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

573413:SPIRS RS15390
gene id: 573413:SPIRS_RS15390
uniprot id: E1R4R2
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS07135
gene id: 573413:SPIRS_RS07135
uniprot id: E1R505
names: Similarity
messages: Belongs to the acetyltransferase family. ArgA subfamily.

573413:SPIRS RS05860
gene id: 573413:SPIRS_RS05860
uniprot id: E1R144
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

573413:SPIRS RS19520
gene id: 573413:SPIRS_RS19520
uniprot id: E1R8Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS12335
gene id: 573413:SPIRS_RS12335
uniprot id: E1R3C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573413:SPIRS RS03625
gene id: 573413:SPIRS_RS03625
uniprot id: E1RBX1
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS07055
gene id: 573413:SPIRS_RS07055
uniprot id: E1R4A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS04225
gene id: 573413:SPIRS_RS04225
uniprot id: E1RC93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS15070
gene id: 573413:SPIRS_RS15070
uniprot id: E1R3W5
names: Similarity
messages: Belongs to the thioredoxin family.

573413:SPIRS RS11550
gene id: 573413:SPIRS_RS11550
uniprot id: E1R1N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

573413:SPIRS RS15575
gene id: 573413:SPIRS_RS15575
uniprot id: E1R4U8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

573413:SPIRS RS04925
gene id: 573413:SPIRS_RS04925
uniprot id: E1RCM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

573413:SPIRS RS08595
gene id: 573413:SPIRS_RS08595
uniprot id: E1R662
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573413:SPIRS RS21180
gene id: 573413:SPIRS_RS21180
uniprot id: E1R9W7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

573413:SPIRS RS16065
gene id: 573413:SPIRS_RS16065
uniprot id: E1R5F6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

573413:SPIRS RS02415
gene id: 573413:SPIRS_RS02415
uniprot id: E1RB93
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

573413:SPIRS RS02980
gene id: 573413:SPIRS_RS02980
uniprot id: E1RBK3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

573413:SPIRS RS06485
gene id: 573413:SPIRS_RS06485
uniprot id: E1R3Z3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

573413:SPIRS RS08435
gene id: 573413:SPIRS_RS08435
uniprot id: E1R630
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

573413:SPIRS RS06055
gene id: 573413:SPIRS_RS06055
uniprot id: E1R2Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Membrane

573413:SPIRS RS06330
gene id: 573413:SPIRS_RS06330
uniprot id: E1R2V3
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

573413:SPIRS RS19870
gene id: 573413:SPIRS_RS19870
uniprot id: E1R959
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

573413:SPIRS RS06070
gene id: 573413:SPIRS_RS06070
uniprot id: E1R2Q3
names: Similarity
messages: Belongs to the creatininase superfamily.

573413:SPIRS RS13080
gene id: 573413:SPIRS_RS13080
uniprot id: E1R4F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

573413:SPIRS RS20050
gene id: 573413:SPIRS_RS20050
uniprot id: E1R995
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

573413:SPIRS RS07110
gene id: 573413:SPIRS_RS07110
uniprot id: E1R500
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573413:SPIRS RS20390
gene id: 573413:SPIRS_RS20390
uniprot id: E1R9G1
names: Similarity
messages: Belongs to the sigma-54 factor family.

573413:SPIRS RS03915
gene id: 573413:SPIRS_RS03915
uniprot id: E1RC30
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

573413:SPIRS RS16565
gene id: 573413:SPIRS_RS16565
uniprot id: E1RAL1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS19090
gene id: 573413:SPIRS_RS19090
uniprot id: E1R817
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

573413:SPIRS RS05750
gene id: 573413:SPIRS_RS05750
uniprot id: E1R123
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

573413:SPIRS RS14880
gene id: 573413:SPIRS_RS14880
uniprot id: E1R3S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS04785
gene id: 573413:SPIRS_RS04785
uniprot id: E1RCJ9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

573413:SPIRS RS21660
gene id: 573413:SPIRS_RS21660
uniprot id: E1RA60
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

573413:SPIRS RS04585
gene id: 573413:SPIRS_RS04585
uniprot id: E1RCG1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS18475
gene id: 573413:SPIRS_RS18475
uniprot id: E1R7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

573413:SPIRS RS06650
gene id: 573413:SPIRS_RS06650
uniprot id: E1R421
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

573413:SPIRS RS01285
gene id: 573413:SPIRS_RS01285
uniprot id: E1RAB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

573413:SPIRS RS01900
gene id: 573413:SPIRS_RS01900
uniprot id: E1RB02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS18360
gene id: 573413:SPIRS_RS18360
uniprot id: E1R7M0
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

573413:SPIRS RS05850
gene id: 573413:SPIRS_RS05850
uniprot id: E1R142
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

573413:SPIRS RS16815
gene id: 573413:SPIRS_RS16815
uniprot id: E1RAQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS12165
gene id: 573413:SPIRS_RS12165
uniprot id: E1R1Z6
names: Similarity
messages: Belongs to the FemABX family.

573413:SPIRS RS08815
gene id: 573413:SPIRS_RS08815
uniprot id: E1R6A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

573413:SPIRS RS15700
gene id: 573413:SPIRS_RS15700
uniprot id: E1R4X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

573413:SPIRS RS10600
gene id: 573413:SPIRS_RS10600
uniprot id: E1R331
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

573413:SPIRS RS00330
gene id: 573413:SPIRS_RS00330
uniprot id: E1R6U5
names: Similarity
messages: Belongs to the DapA family.

573413:SPIRS RS06120
gene id: 573413:SPIRS_RS06120
uniprot id: E1R2R1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

573413:SPIRS RS05525
gene id: 573413:SPIRS_RS05525
uniprot id: E1R0X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS02815
gene id: 573413:SPIRS_RS02815
uniprot id: E1RBG9
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS20495
gene id: 573413:SPIRS_RS20495
uniprot id: E1R9I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

573413:SPIRS RS15840
gene id: 573413:SPIRS_RS15840
uniprot id: E1R5B0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

573413:SPIRS RS12075
gene id: 573413:SPIRS_RS12075
uniprot id: E1R1X8
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

573413:SPIRS RS17525
gene id: 573413:SPIRS_RS17525
uniprot id: E1R2K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS00035
gene id: 573413:SPIRS_RS00035
uniprot id: E1R6N6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

573413:SPIRS RS18195
gene id: 573413:SPIRS_RS18195
uniprot id: E1R7I9
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS20135
gene id: 573413:SPIRS_RS20135
uniprot id: E1R9B2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573413:SPIRS RS17845
gene id: 573413:SPIRS_RS17845
uniprot id: E1R7C0
names: Similarity
messages: Belongs to the CarB family.

573413:SPIRS RS06280
gene id: 573413:SPIRS_RS06280
uniprot id: E1R2U3
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS06750
gene id: 573413:SPIRS_RS06750
uniprot id: E1R441
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

573413:SPIRS RS06905
gene id: 573413:SPIRS_RS06905
uniprot id: E1R472
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS10850
gene id: 573413:SPIRS_RS10850
uniprot id: E1R381
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

573413:SPIRS RS17715
gene id: 573413:SPIRS_RS17715
uniprot id: E1R794
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

573413:SPIRS RS02915
gene id: 573413:SPIRS_RS02915
uniprot id: E1RBI9
names: Similarity
messages: Belongs to the aspartokinase family.

573413:SPIRS RS09115
gene id: 573413:SPIRS_RS09115
uniprot id: E1R6A9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

573413:SPIRS RS18970
gene id: 573413:SPIRS_RS18970
uniprot id: E1R7Z4
names: Cofactor
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

573413:SPIRS RS03365
gene id: 573413:SPIRS_RS03365
uniprot id: E1RBS4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573413:SPIRS RS16670
gene id: 573413:SPIRS_RS16670
uniprot id: E1RAN0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

573413:SPIRS RS05990
gene id: 573413:SPIRS_RS05990
uniprot id: E1R2N7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

573413:SPIRS RS02490
gene id: 573413:SPIRS_RS02490
uniprot id: E1RBA8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

573413:SPIRS RS15685
gene id: 573413:SPIRS_RS15685
uniprot id: E1R4W9
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

573413:SPIRS RS19565
gene id: 573413:SPIRS_RS19565
uniprot id: E1R8Z8
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

573413:SPIRS RS15245
gene id: 573413:SPIRS_RS15245
uniprot id: E1R4N3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

573413:SPIRS RS00335
gene id: 573413:SPIRS_RS00335
uniprot id: E1R6U6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

573413:SPIRS RS16550
gene id: 573413:SPIRS_RS16550
uniprot id: E1RAK8
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

573413:SPIRS RS18645
gene id: 573413:SPIRS_RS18645
uniprot id: E1R7S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

573413:SPIRS RS00830
gene id: 573413:SPIRS_RS00830
uniprot id: E1R8H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

573413:SPIRS RS07805
gene id: 573413:SPIRS_RS07805
uniprot id: E1R5Q4
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

573413:SPIRS RS19940
gene id: 573413:SPIRS_RS19940
uniprot id: E1R973
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS16470
gene id: 573413:SPIRS_RS16470
uniprot id: E1RAJ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

573413:SPIRS RS03840
gene id: 573413:SPIRS_RS03840
uniprot id: E1RC14
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS19215
gene id: 573413:SPIRS_RS19215
uniprot id: E1R842
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573413:SPIRS RS17500
gene id: 573413:SPIRS_RS17500
uniprot id: E1R2J6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

573413:SPIRS RS08225
gene id: 573413:SPIRS_RS08225
uniprot id: E1R5Y9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

573413:SPIRS RS21360
gene id: 573413:SPIRS_RS21360
uniprot id: E1RA01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

573413:SPIRS RS06175
gene id: 573413:SPIRS_RS06175
uniprot id: E1R2S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS03645
gene id: 573413:SPIRS_RS03645
uniprot id: E1RBX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS16035
gene id: 573413:SPIRS_RS16035
uniprot id: E1R5F0
names: Similarity
messages: Belongs to the CinA family.

573413:SPIRS RS17700
gene id: 573413:SPIRS_RS17700
uniprot id: E1R791
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

573413:SPIRS RS08060
gene id: 573413:SPIRS_RS08060
uniprot id: E1R5V5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

573413:SPIRS RS16390
gene id: 573413:SPIRS_RS16390
uniprot id: E1R5L6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573413:SPIRS RS16345
gene id: 573413:SPIRS_RS16345
uniprot id: E1R5K7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

573413:SPIRS RS11595
gene id: 573413:SPIRS_RS11595
uniprot id: E1R1N9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

573413:SPIRS RS16500
gene id: 573413:SPIRS_RS16500
uniprot id: E1RAJ8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS04670
gene id: 573413:SPIRS_RS04670
uniprot id: E1RCH8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

573413:SPIRS RS02675
gene id: 573413:SPIRS_RS02675
uniprot id: E1RBE3
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS07370
gene id: 573413:SPIRS_RS07370
uniprot id: E1R552
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

573413:SPIRS RS04865
gene id: 573413:SPIRS_RS04865
uniprot id: E1RCL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

573413:SPIRS RS05120
gene id: 573413:SPIRS_RS05120
uniprot id: E1RCR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

573413:SPIRS RS04780
gene id: 573413:SPIRS_RS04780
uniprot id: E1RCJ8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

573413:SPIRS RS14700
gene id: 573413:SPIRS_RS14700
uniprot id: E1R3P3
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

573413:SPIRS RS22335
gene id: 573413:SPIRS_RS22335
uniprot id: E1RCJ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

573413:SPIRS RS13090
gene id: 573413:SPIRS_RS13090
uniprot id: E1R4G1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

573413:SPIRS RS04820
gene id: 573413:SPIRS_RS04820
uniprot id: E1RCK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

573413:SPIRS RS06050
gene id: 573413:SPIRS_RS06050
uniprot id: E1R2P9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

573413:SPIRS RS15120
gene id: 573413:SPIRS_RS15120
uniprot id: E1R3X5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

573413:SPIRS RS04890
gene id: 573413:SPIRS_RS04890
uniprot id: E1RCM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

573413:SPIRS RS18920
gene id: 573413:SPIRS_RS18920
uniprot id: E1R7Y3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

573413:SPIRS RS07890
gene id: 573413:SPIRS_RS07890
uniprot id: E1R5S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

573413:SPIRS RS08450
gene id: 573413:SPIRS_RS08450
uniprot id: E1R633
names: Similarity
messages: Belongs to the DapA family.

573413:SPIRS RS14920
gene id: 573413:SPIRS_RS14920
uniprot id: E1R3T6
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS02465
gene id: 573413:SPIRS_RS02465
uniprot id: E1RBA3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

573413:SPIRS RS08605
gene id: 573413:SPIRS_RS08605
uniprot id: E1R664
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

573413:SPIRS RS03785
gene id: 573413:SPIRS_RS03785
uniprot id: E1RC03
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

573413:SPIRS RS07940
gene id: 573413:SPIRS_RS07940
uniprot id: E1R5T1
names: Similarity
messages: Belongs to the FlgD family.

573413:SPIRS RS13700
gene id: 573413:SPIRS_RS13700
uniprot id: E1R8R3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

573413:SPIRS RS17775
gene id: 573413:SPIRS_RS17775
uniprot id: E1R7A6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS02695
gene id: 573413:SPIRS_RS02695
uniprot id: E1RBE7
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS11540
gene id: 573413:SPIRS_RS11540
uniprot id: E1R1M8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

573413:SPIRS RS15775
gene id: 573413:SPIRS_RS15775
uniprot id: E1R4Y7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

573413:SPIRS RS03205
gene id: 573413:SPIRS_RS03205
uniprot id: E1RBP4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

573413:SPIRS RS03265
gene id: 573413:SPIRS_RS03265
uniprot id: E1RBQ6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

573413:SPIRS RS10295
gene id: 573413:SPIRS_RS10295
uniprot id: E1R1L8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

573413:SPIRS RS05270
gene id: 573413:SPIRS_RS05270
uniprot id: E1RCU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

573413:SPIRS RS11400
gene id: 573413:SPIRS_RS11400
uniprot id: E1R749
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS07260
gene id: 573413:SPIRS_RS07260
uniprot id: E1R531
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

573413:SPIRS RS16620
gene id: 573413:SPIRS_RS16620
uniprot id: E1RAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

573413:SPIRS RS01560
gene id: 573413:SPIRS_RS01560
uniprot id: E1RAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS07180
gene id: 573413:SPIRS_RS07180
uniprot id: E1R514
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

573413:SPIRS RS05530
gene id: 573413:SPIRS_RS05530
uniprot id: E1R0Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS12805
gene id: 573413:SPIRS_RS12805
uniprot id: E1R4A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

573413:SPIRS RS11340
gene id: 573413:SPIRS_RS11340
uniprot id: E1R737
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS04180
gene id: 573413:SPIRS_RS04180
uniprot id: E1RC84
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

573413:SPIRS RS07870
gene id: 573413:SPIRS_RS07870
uniprot id: E1R5R7
names: Similarity
messages: Belongs to the DprA/Smf family.

573413:SPIRS RS17475
gene id: 573413:SPIRS_RS17475
uniprot id: E1R2J1
names: Similarity
messages: Belongs to the creatininase superfamily.

573413:SPIRS RS05365
gene id: 573413:SPIRS_RS05365
uniprot id: E1R0U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS00515
gene id: 573413:SPIRS_RS00515
uniprot id: E1R8B6
names: Similarity
messages: Belongs to the thymidine kinase family.

573413:SPIRS RS01145
gene id: 573413:SPIRS_RS01145
uniprot id: E1RA92
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

573413:SPIRS RS06555
gene id: 573413:SPIRS_RS06555
uniprot id: E1R402
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

573413:SPIRS RS04895
gene id: 573413:SPIRS_RS04895
uniprot id: E1RCM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

573413:SPIRS RS20440
gene id: 573413:SPIRS_RS20440
uniprot id: E1R9H1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS09255
gene id: 573413:SPIRS_RS09255
uniprot id: E1R6D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

573413:SPIRS RS07625
gene id: 573413:SPIRS_RS07625
uniprot id: E1R5M4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

573413:SPIRS RS04920
gene id: 573413:SPIRS_RS04920
uniprot id: E1RCM7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

573413:SPIRS RS02410
gene id: 573413:SPIRS_RS02410
uniprot id: E1RB92
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

573413:SPIRS RS11580
gene id: 573413:SPIRS_RS11580
uniprot id: E1R1N6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

573413:SPIRS RS03150
gene id: 573413:SPIRS_RS03150
uniprot id: E1RBN3
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

573413:SPIRS RS18540
gene id: 573413:SPIRS_RS18540
uniprot id: E1R7Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

573413:SPIRS RS09060
gene id: 573413:SPIRS_RS09060
uniprot id: E1R198
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

573413:SPIRS RS10180
gene id: 573413:SPIRS_RS10180
uniprot id: E1R1J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

573413:SPIRS RS11575
gene id: 573413:SPIRS_RS11575
uniprot id: E1R1N5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

573413:SPIRS RS08960
gene id: 573413:SPIRS_RS08960
uniprot id: E1R179
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS04560
gene id: 573413:SPIRS_RS04560
uniprot id: E1RCF6
names: Similarity
messages: Belongs to the glycosyl hydrolase 100 family.

573413:SPIRS RS18295
gene id: 573413:SPIRS_RS18295
uniprot id: E1R7K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

573413:SPIRS RS19300
gene id: 573413:SPIRS_RS19300
uniprot id: E1R860
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

573413:SPIRS RS01785
gene id: 573413:SPIRS_RS01785
uniprot id: E1RAX9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

573413:SPIRS RS11700
gene id: 573413:SPIRS_RS11700
uniprot id: E1R1Q8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS21465
gene id: 573413:SPIRS_RS21465
uniprot id: E1RA22
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS10210
gene id: 573413:SPIRS_RS10210
uniprot id: E1R1K1
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

573413:SPIRS RS04530
gene id: 573413:SPIRS_RS04530
uniprot id: E1RCF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS20670
gene id: 573413:SPIRS_RS20670
uniprot id: E1R9L8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

573413:SPIRS RS11500
gene id: 573413:SPIRS_RS11500
uniprot id: E1R769
names: Similarity
messages: Belongs to the YicC/YloC family.

573413:SPIRS RS16155
gene id: 573413:SPIRS_RS16155
uniprot id: E1R5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

573413:SPIRS RS07960
gene id: 573413:SPIRS_RS07960
uniprot id: E1R5T5
names: Similarity
messages: Belongs to the MotB family.

573413:SPIRS RS18750
gene id: 573413:SPIRS_RS18750
uniprot id: E1R7U9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS05245
gene id: 573413:SPIRS_RS05245
uniprot id: E1RCU3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

573413:SPIRS RS21400
gene id: 573413:SPIRS_RS21400
uniprot id: E1RA09
names: Similarity
messages: Belongs to the FemABX family.

573413:SPIRS RS19245
gene id: 573413:SPIRS_RS19245
uniprot id: E1R849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS06780
gene id: 573413:SPIRS_RS06780
uniprot id: E1R447
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

573413:SPIRS RS05940
gene id: 573413:SPIRS_RS05940
uniprot id: E1R2M7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

573413:SPIRS RS07855
gene id: 573413:SPIRS_RS07855
uniprot id: E1R5R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

573413:SPIRS RS08585
gene id: 573413:SPIRS_RS08585
uniprot id: E1R660
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

573413:SPIRS RS09080
gene id: 573413:SPIRS_RS09080
uniprot id: E1R1A2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

573413:SPIRS RS20760
gene id: 573413:SPIRS_RS20760
uniprot id: E1R9N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

573413:SPIRS RS11270
gene id: 573413:SPIRS_RS11270
uniprot id: E1R722
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

573413:SPIRS RS18655
gene id: 573413:SPIRS_RS18655
uniprot id: E1R7T0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS14425
gene id: 573413:SPIRS_RS14425
uniprot id: E1R274
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

573413:SPIRS RS06005
gene id: 573413:SPIRS_RS06005
uniprot id: E1R2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS00770
gene id: 573413:SPIRS_RS00770
uniprot id: E1R8G5
names: Similarity
messages: Belongs to the UPF0047 family.

573413:SPIRS RS10905
gene id: 573413:SPIRS_RS10905
uniprot id: E1R392
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

573413:SPIRS RS10480
gene id: 573413:SPIRS_RS10480
uniprot id: E1R310
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

573413:SPIRS RS11290
gene id: 573413:SPIRS_RS11290
uniprot id: E1R727
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

573413:SPIRS RS00920
gene id: 573413:SPIRS_RS00920
uniprot id: E1R8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

573413:SPIRS RS20405
gene id: 573413:SPIRS_RS20405
uniprot id: E1R9G4
names: Subcellular Location Annotation
messages: Cytoplasm

573413:SPIRS RS13915
gene id: 573413:SPIRS_RS13915
uniprot id: E1R8V4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

573413:SPIRS RS04005
gene id: 573413:SPIRS_RS04005
uniprot id: E1RC48
names: Similarity
messages: Belongs to the DapA family.

573413:SPIRS RS04680
gene id: 573413:SPIRS_RS04680
uniprot id: E1RCI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

573413:SPIRS RS09700
gene id: 573413:SPIRS_RS09700
uniprot id: E1R6M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

573413:SPIRS RS17200
gene id: 573413:SPIRS_RS17200
uniprot id: E1R2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS10385
gene id: 573413:SPIRS_RS10385
uniprot id: E1R2Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

573413:SPIRS RS01485
gene id: 573413:SPIRS_RS01485
uniprot id: E1RAF9
names: Similarity
messages: Belongs to the WrbA family.

573413:SPIRS RS19580
gene id: 573413:SPIRS_RS19580
uniprot id: E1R901
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS01105
gene id: 573413:SPIRS_RS01105
uniprot id: E1RA84
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS21300
gene id: 573413:SPIRS_RS21300
uniprot id: E1R9Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

573413:SPIRS RS10595
gene id: 573413:SPIRS_RS10595
uniprot id: E1R330
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

573413:SPIRS RS09560
gene id: 573413:SPIRS_RS09560
uniprot id: E1R6J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

573413:SPIRS RS02865
gene id: 573413:SPIRS_RS02865
uniprot id: E1RBH9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS10250
gene id: 573413:SPIRS_RS10250
uniprot id: E1R1K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

573413:SPIRS RS15735
gene id: 573413:SPIRS_RS15735
uniprot id: E1R4X9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

573413:SPIRS RS12160
gene id: 573413:SPIRS_RS12160
uniprot id: E1R1Z5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

573413:SPIRS RS14890
gene id: 573413:SPIRS_RS14890
uniprot id: E1R3T0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

573413:SPIRS RS14400
gene id: 573413:SPIRS_RS14400
uniprot id: E1R269
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

573413:SPIRS RS03525
gene id: 573413:SPIRS_RS03525
uniprot id: E1RBV3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

573413:SPIRS RS19360
gene id: 573413:SPIRS_RS19360
uniprot id: E1R872
names: Similarity
messages: Belongs to the LarC family.

573413:SPIRS RS00125
gene id: 573413:SPIRS_RS00125
uniprot id: E1R6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS07885
gene id: 573413:SPIRS_RS07885
uniprot id: E1R5S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

573413:SPIRS RS04915
gene id: 573413:SPIRS_RS04915
uniprot id: E1RCM6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

573413:SPIRS RS17315
gene id: 573413:SPIRS_RS17315
uniprot id: E1R2G0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

573413:SPIRS RS18105
gene id: 573413:SPIRS_RS18105
uniprot id: E1R7H1
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

573413:SPIRS RS05710
gene id: 573413:SPIRS_RS05710
uniprot id: E1R115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

573413:SPIRS RS00900
gene id: 573413:SPIRS_RS00900
uniprot id: E1R8J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573413:SPIRS RS21505
gene id: 573413:SPIRS_RS21505
uniprot id: E1RA29
names: Similarity
messages: Belongs to the HepT RNase toxin family.

573413:SPIRS RS05240
gene id: 573413:SPIRS_RS05240
uniprot id: E1RCU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS14555
gene id: 573413:SPIRS_RS14555
uniprot id: E1R2A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS17865
gene id: 573413:SPIRS_RS17865
uniprot id: E1R7C4
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

573413:SPIRS RS13540
gene id: 573413:SPIRS_RS13540
uniprot id: E1R8N1
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS06600
gene id: 573413:SPIRS_RS06600
uniprot id: E1R411
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

573413:SPIRS RS02670
gene id: 573413:SPIRS_RS02670
uniprot id: E1RBE2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

573413:SPIRS RS20070
gene id: 573413:SPIRS_RS20070
uniprot id: E1R999
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

573413:SPIRS RS08520
gene id: 573413:SPIRS_RS08520
uniprot id: E1R647
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

573413:SPIRS RS05745
gene id: 573413:SPIRS_RS05745
uniprot id: E1R122
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

573413:SPIRS RS06520
gene id: 573413:SPIRS_RS06520
uniprot id: E1R400
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

573413:SPIRS RS07425
gene id: 573413:SPIRS_RS07425
uniprot id: E1R563
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

573413:SPIRS RS18725
gene id: 573413:SPIRS_RS18725
uniprot id: E1R7U4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS07550
gene id: 573413:SPIRS_RS07550
uniprot id: E1R588
names: Similarity
messages: Belongs to the UPF0164 family.

573413:SPIRS RS07910
gene id: 573413:SPIRS_RS07910
uniprot id: E1R5S5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

573413:SPIRS RS05280
gene id: 573413:SPIRS_RS05280
uniprot id: E1RCV0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

573413:SPIRS RS02535
gene id: 573413:SPIRS_RS02535
uniprot id: E1RBB7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

573413:SPIRS RS10885
gene id: 573413:SPIRS_RS10885
uniprot id: E1R388
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

573413:SPIRS RS14460
gene id: 573413:SPIRS_RS14460
uniprot id: E1R281
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

573413:SPIRS RS08535
gene id: 573413:SPIRS_RS08535
uniprot id: E1R650
names: Similarity
messages: Belongs to the peptidase M16 family.

573413:SPIRS RS01780
gene id: 573413:SPIRS_RS01780
uniprot id: E1RAX8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

573413:SPIRS RS06730
gene id: 573413:SPIRS_RS06730
uniprot id: E1R437
names: Similarity
messages: Belongs to the polysaccharide synthase family.

573413:SPIRS RS05075
gene id: 573413:SPIRS_RS05075
uniprot id: E1RCQ9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

573413:SPIRS RS01075
gene id: 573413:SPIRS_RS01075
uniprot id: E1RA78
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS13910
gene id: 573413:SPIRS_RS13910
uniprot id: E1R8V3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

573413:SPIRS RS10505
gene id: 573413:SPIRS_RS10505
uniprot id: E1R314
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

573413:SPIRS RS17530
gene id: 573413:SPIRS_RS17530
uniprot id: E1R2K2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

573413:SPIRS RS06405
gene id: 573413:SPIRS_RS06405
uniprot id: E1R2W8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS18200
gene id: 573413:SPIRS_RS18200
uniprot id: E1R7J0
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

573413:SPIRS RS17935
gene id: 573413:SPIRS_RS17935
uniprot id: E1R7D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

573413:SPIRS RS09045
gene id: 573413:SPIRS_RS09045
uniprot id: E1R195
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

573413:SPIRS RS00670
gene id: 573413:SPIRS_RS00670
uniprot id: E1R8E5
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS03710
gene id: 573413:SPIRS_RS03710
uniprot id: E1RBY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS20610
gene id: 573413:SPIRS_RS20610
uniprot id: E1R9K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS15890
gene id: 573413:SPIRS_RS15890
uniprot id: E1R5B9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

573413:SPIRS RS19775
gene id: 573413:SPIRS_RS19775
uniprot id: E1R940
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS04465
gene id: 573413:SPIRS_RS04465
uniprot id: E1RCD7
names: Similarity
messages: Belongs to the threonine synthase family.

573413:SPIRS RS10200
gene id: 573413:SPIRS_RS10200
uniprot id: E1R1J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

573413:SPIRS RS04260
gene id: 573413:SPIRS_RS04260
uniprot id: E1RC99
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS05205
gene id: 573413:SPIRS_RS05205
uniprot id: E1RCT5
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS05315
gene id: 573413:SPIRS_RS05315
uniprot id: E1R0T8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS10855
gene id: 573413:SPIRS_RS10855
uniprot id: E1R382
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

573413:SPIRS RS07345
gene id: 573413:SPIRS_RS07345
uniprot id: E1R547
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

573413:SPIRS RS17570
gene id: 573413:SPIRS_RS17570
uniprot id: E1R2L0
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

573413:SPIRS RS02495
gene id: 573413:SPIRS_RS02495
uniprot id: E1RBA9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573413:SPIRS RS00025
gene id: 573413:SPIRS_RS00025
uniprot id: E1R6N4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

573413:SPIRS RS05410
gene id: 573413:SPIRS_RS05410
uniprot id: E1R0V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

573413:SPIRS RS00570
gene id: 573413:SPIRS_RS00570
uniprot id: E1R8C5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

573413:SPIRS RS19900
gene id: 573413:SPIRS_RS19900
uniprot id: E1R965
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573413:SPIRS RS04830
gene id: 573413:SPIRS_RS04830
uniprot id: E1RCK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

573413:SPIRS RS17665
gene id: 573413:SPIRS_RS17665
uniprot id: E1R784
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

573413:SPIRS RS08120
gene id: 573413:SPIRS_RS08120
uniprot id: E1R5W8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS09520
gene id: 573413:SPIRS_RS09520
uniprot id: E1R6I8
names: Similarity
messages: Belongs to the UPF0102 family.

573413:SPIRS RS18270
gene id: 573413:SPIRS_RS18270
uniprot id: E1R7K2
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

573413:SPIRS RS02620
gene id: 573413:SPIRS_RS02620
uniprot id: E1RBD2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS07895
gene id: 573413:SPIRS_RS07895
uniprot id: E1R5S2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

573413:SPIRS RS00045
gene id: 573413:SPIRS_RS00045
uniprot id: E1R6N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

573413:SPIRS RS12365
gene id: 573413:SPIRS_RS12365
uniprot id: E1R3D1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

573413:SPIRS RS15615
gene id: 573413:SPIRS_RS15615
uniprot id: E1R4V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

573413:SPIRS RS21450
gene id: 573413:SPIRS_RS21450
uniprot id: E1RA19
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

573413:SPIRS RS20015
gene id: 573413:SPIRS_RS20015
uniprot id: E1R988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

573413:SPIRS RS05670
gene id: 573413:SPIRS_RS05670
uniprot id: E1R108
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

573413:SPIRS RS10340
gene id: 573413:SPIRS_RS10340
uniprot id: E1R2Y2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

573413:SPIRS RS20490
gene id: 573413:SPIRS_RS20490
uniprot id: E1R9I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

573413:SPIRS RS17465
gene id: 573413:SPIRS_RS17465
uniprot id: E1R2I9
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

573413:SPIRS RS15180
gene id: 573413:SPIRS_RS15180
uniprot id: E1R3Y7
names: Similarity
messages: Belongs to the P(II) protein family.

573413:SPIRS RS10735
gene id: 573413:SPIRS_RS10735
uniprot id: E1R358
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

573413:SPIRS RS19025
gene id: 573413:SPIRS_RS19025
uniprot id: E1R804
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573413:SPIRS RS10275
gene id: 573413:SPIRS_RS10275
uniprot id: E1R1L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

573413:SPIRS RS12175
gene id: 573413:SPIRS_RS12175
uniprot id: E1R1Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS16325
gene id: 573413:SPIRS_RS16325
uniprot id: E1R5K3
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

573413:SPIRS RS09545
gene id: 573413:SPIRS_RS09545
uniprot id: E1R6J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

573413:SPIRS RS14570
gene id: 573413:SPIRS_RS14570
uniprot id: E1R3L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.

573413:SPIRS RS04280
gene id: 573413:SPIRS_RS04280
uniprot id: E1RCA3
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

573413:SPIRS RS14015
gene id: 573413:SPIRS_RS14015
uniprot id: E1R8X3
names: Similarity
messages: Belongs to the DtxR/MntR family.

573413:SPIRS RS09660
gene id: 573413:SPIRS_RS09660
uniprot id: E1R6L7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

573413:SPIRS RS15675
gene id: 573413:SPIRS_RS15675
uniprot id: E1R4W7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

573413:SPIRS RS13070
gene id: 573413:SPIRS_RS13070
uniprot id: E1R4F7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

573413:SPIRS RS04960
gene id: 573413:SPIRS_RS04960
uniprot id: E1RCN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

573413:SPIRS RS09155
gene id: 573413:SPIRS_RS09155
uniprot id: E1R6B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

573413:SPIRS RS02790
gene id: 573413:SPIRS_RS02790
uniprot id: E1RBG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS12825
gene id: 573413:SPIRS_RS12825
uniprot id: E1R4B0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS01100
gene id: 573413:SPIRS_RS01100
uniprot id: E1RA83
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS18155
gene id: 573413:SPIRS_RS18155
uniprot id: E1R7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS11195
gene id: 573413:SPIRS_RS11195
uniprot id: E1R707
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS05060
gene id: 573413:SPIRS_RS05060
uniprot id: E1RCQ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

573413:SPIRS RS10190
gene id: 573413:SPIRS_RS10190
uniprot id: E1R1J7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

573413:SPIRS RS11770
gene id: 573413:SPIRS_RS11770
uniprot id: E1R1S2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

573413:SPIRS RS09845
gene id: 573413:SPIRS_RS09845
uniprot id: E1R1D1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

573413:SPIRS RS18615
gene id: 573413:SPIRS_RS18615
uniprot id: E1R7S2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

573413:SPIRS RS09315
gene id: 573413:SPIRS_RS09315
uniprot id: E1R6E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS11220
gene id: 573413:SPIRS_RS11220
uniprot id: E1R712
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573413:SPIRS RS20485
gene id: 573413:SPIRS_RS20485
uniprot id: E1R9I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS11990
gene id: 573413:SPIRS_RS11990
uniprot id: E1R1W5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

573413:SPIRS RS05805
gene id: 573413:SPIRS_RS05805
uniprot id: E1R134
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

573413:SPIRS RS11955
gene id: 573413:SPIRS_RS11955
uniprot id: E1R1V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

573413:SPIRS RS01415
gene id: 573413:SPIRS_RS01415
uniprot id: E1RAE5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

573413:SPIRS RS13985
gene id: 573413:SPIRS_RS13985
uniprot id: E1R8W7
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

573413:SPIRS RS20845
gene id: 573413:SPIRS_RS20845
uniprot id: E1R9Q2
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS13900
gene id: 573413:SPIRS_RS13900
uniprot id: E1R8V1
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

573413:SPIRS RS08455
gene id: 573413:SPIRS_RS08455
uniprot id: E1R634
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

573413:SPIRS RS08335
gene id: 573413:SPIRS_RS08335
uniprot id: E1R611
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

573413:SPIRS RS10775
gene id: 573413:SPIRS_RS10775
uniprot id: E1R366
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

573413:SPIRS RS10800
gene id: 573413:SPIRS_RS10800
uniprot id: E1R371
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS13045
gene id: 573413:SPIRS_RS13045
uniprot id: E1R4F2
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS12810
gene id: 573413:SPIRS_RS12810
uniprot id: E1R4A7
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS14895
gene id: 573413:SPIRS_RS14895
uniprot id: E1R3T1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

573413:SPIRS RS18350
gene id: 573413:SPIRS_RS18350
uniprot id: E1R7L8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

573413:SPIRS RS13480
gene id: 573413:SPIRS_RS13480
uniprot id: E1R8L9
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS10880
gene id: 573413:SPIRS_RS10880
uniprot id: E1R387
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

573413:SPIRS RS19460
gene id: 573413:SPIRS_RS19460
uniprot id: E1R8X7
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS04930
gene id: 573413:SPIRS_RS04930
uniprot id: E1RCM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

573413:SPIRS RS12460
gene id: 573413:SPIRS_RS12460
uniprot id: E1R3F0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

573413:SPIRS RS12420
gene id: 573413:SPIRS_RS12420
uniprot id: E1R3E2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

573413:SPIRS RS00520
gene id: 573413:SPIRS_RS00520
uniprot id: E1R8B7
names: Similarity
messages: Belongs to the hemerythrin family.

573413:SPIRS RS07990
gene id: 573413:SPIRS_RS07990
uniprot id: E1R5U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

573413:SPIRS RS02880
gene id: 573413:SPIRS_RS02880
uniprot id: E1RBI2
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS07720
gene id: 573413:SPIRS_RS07720
uniprot id: E1R5P1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573413:SPIRS RS04810
gene id: 573413:SPIRS_RS04810
uniprot id: E1RCK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

573413:SPIRS RS17305
gene id: 573413:SPIRS_RS17305
uniprot id: E1R2F8
names: Similarity
messages: Belongs to the ribulokinase family.

573413:SPIRS RS05590
gene id: 573413:SPIRS_RS05590
uniprot id: E1R0Z2
names: Similarity
messages: Belongs to the UxaA family.

573413:SPIRS RS04250
gene id: 573413:SPIRS_RS04250
uniprot id: E1RC97
names: Similarity
messages: Belongs to the BMP lipoprotein family.

573413:SPIRS RS17130
gene id: 573413:SPIRS_RS17130
uniprot id: E1R2C3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

573413:SPIRS RS19000
gene id: 573413:SPIRS_RS19000
uniprot id: E1R800
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

573413:SPIRS RS16245
gene id: 573413:SPIRS_RS16245
uniprot id: E1R5J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS15865
gene id: 573413:SPIRS_RS15865
uniprot id: E1R5B5
names: Subcellular Location Annotation
messages: Cytoplasm

573413:SPIRS RS00990
gene id: 573413:SPIRS_RS00990
uniprot id: E1R8K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS12260
gene id: 573413:SPIRS_RS12260
uniprot id: E1R3B0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

573413:SPIRS RS10165
gene id: 573413:SPIRS_RS10165
uniprot id: E1R1J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

573413:SPIRS RS17830
gene id: 573413:SPIRS_RS17830
uniprot id: E1R7B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS19590
gene id: 573413:SPIRS_RS19590
uniprot id: E1R903
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

573413:SPIRS RS18115
gene id: 573413:SPIRS_RS18115
uniprot id: E1R7H3
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

573413:SPIRS RS10895
gene id: 573413:SPIRS_RS10895
uniprot id: E1R390
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573413:SPIRS RS20890
gene id: 573413:SPIRS_RS20890
uniprot id: E1R9R1
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

573413:SPIRS RS21085
gene id: 573413:SPIRS_RS21085
uniprot id: E1R9V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS09565
gene id: 573413:SPIRS_RS09565
uniprot id: E1R6J8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

573413:SPIRS RS11980
gene id: 573413:SPIRS_RS11980
uniprot id: E1R1W3
names: Similarity
messages: Belongs to the UPF0047 family.

573413:SPIRS RS15815
gene id: 573413:SPIRS_RS15815
uniprot id: E1R5A5
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

573413:SPIRS RS17870
gene id: 573413:SPIRS_RS17870
uniprot id: E1R7C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

573413:SPIRS RS03450
gene id: 573413:SPIRS_RS03450
uniprot id: E1RBU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

573413:SPIRS RS06510
gene id: 573413:SPIRS_RS06510
uniprot id: E1R3Z8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

573413:SPIRS RS15205
gene id: 573413:SPIRS_RS15205
uniprot id: E1R4M5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

573413:SPIRS RS21550
gene id: 573413:SPIRS_RS21550
uniprot id: E1RA38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

573413:SPIRS RS11275
gene id: 573413:SPIRS_RS11275
uniprot id: E1R723
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

573413:SPIRS RS11455
gene id: 573413:SPIRS_RS11455
uniprot id: E1R760
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

573413:SPIRS RS07040
gene id: 573413:SPIRS_RS07040
uniprot id: E1R499
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

573413:SPIRS RS09460
gene id: 573413:SPIRS_RS09460
uniprot id: E1R6H6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

573413:SPIRS RS20640
gene id: 573413:SPIRS_RS20640
uniprot id: E1R9L1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

573413:SPIRS RS03955
gene id: 573413:SPIRS_RS03955
uniprot id: E1RC38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS16240
gene id: 573413:SPIRS_RS16240
uniprot id: E1R5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS11545
gene id: 573413:SPIRS_RS11545
uniprot id: E1R1M9
names: Similarity
messages: Belongs to the Nth/MutY family.

573413:SPIRS RS09720
gene id: 573413:SPIRS_RS09720
uniprot id: E1R1A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

573413:SPIRS RS12385
gene id: 573413:SPIRS_RS12385
uniprot id: E1R3D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

573413:SPIRS RS20225
gene id: 573413:SPIRS_RS20225
uniprot id: E1R9C9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

573413:SPIRS RS02810
gene id: 573413:SPIRS_RS02810
uniprot id: E1RBG8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS06840
gene id: 573413:SPIRS_RS06840
uniprot id: E1R459
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS13065
gene id: 573413:SPIRS_RS13065
uniprot id: E1R4F6
names: Subcellular Location Annotation
messages: Periplasmic flagellum

573413:SPIRS RS11825
gene id: 573413:SPIRS_RS11825
uniprot id: E1R1T3
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS10225
gene id: 573413:SPIRS_RS10225
uniprot id: E1R1K4
names: Similarity
messages: Belongs to the Skp family.

573413:SPIRS RS04910
gene id: 573413:SPIRS_RS04910
uniprot id: E1RCM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

573413:SPIRS RS18830
gene id: 573413:SPIRS_RS18830
uniprot id: E1R7W5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

573413:SPIRS RS12185
gene id: 573413:SPIRS_RS12185
uniprot id: E1R395
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Membrane

573413:SPIRS RS02975
gene id: 573413:SPIRS_RS02975
uniprot id: E1RBK2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

573413:SPIRS RS10510
gene id: 573413:SPIRS_RS10510
uniprot id: E1R315
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

573413:SPIRS RS02970
gene id: 573413:SPIRS_RS02970
uniprot id: E1RBK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

573413:SPIRS RS13475
gene id: 573413:SPIRS_RS13475
uniprot id: E1R8L8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS17680
gene id: 573413:SPIRS_RS17680
uniprot id: E1R787
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

573413:SPIRS RS03965
gene id: 573413:SPIRS_RS03965
uniprot id: E1RC40
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

573413:SPIRS RS07215
gene id: 573413:SPIRS_RS07215
uniprot id: E1R521
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS03775
gene id: 573413:SPIRS_RS03775
uniprot id: E1RC01
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

573413:SPIRS RS15465
gene id: 573413:SPIRS_RS15465
uniprot id: E1R4S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS02590
gene id: 573413:SPIRS_RS02590
uniprot id: E1RBC6
names: Similarity
messages: Belongs to the DapA family.

573413:SPIRS RS03510
gene id: 573413:SPIRS_RS03510
uniprot id: E1RBV1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

573413:SPIRS RS07850
gene id: 573413:SPIRS_RS07850
uniprot id: E1R5R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

573413:SPIRS RS19975
gene id: 573413:SPIRS_RS19975
uniprot id: E1R980
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS05250
gene id: 573413:SPIRS_RS05250
uniprot id: E1RCU4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

573413:SPIRS RS07760
gene id: 573413:SPIRS_RS07760
uniprot id: E1R5P5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

573413:SPIRS RS10380
gene id: 573413:SPIRS_RS10380
uniprot id: E1R2Z0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

573413:SPIRS RS15875
gene id: 573413:SPIRS_RS15875
uniprot id: E1R5B7
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS20215
gene id: 573413:SPIRS_RS20215
uniprot id: E1R9C7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573413:SPIRS RS07495
gene id: 573413:SPIRS_RS07495
uniprot id: E1R577
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS04220
gene id: 573413:SPIRS_RS04220
uniprot id: E1RC92
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

573413:SPIRS RS06880
gene id: 573413:SPIRS_RS06880
uniprot id: E1R467
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

573413:SPIRS RS17495
gene id: 573413:SPIRS_RS17495
uniprot id: E1R2J5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

573413:SPIRS RS11740
gene id: 573413:SPIRS_RS11740
uniprot id: E1R1R6
names: Similarity
messages: Belongs to the glutamate synthase family.

573413:SPIRS RS17920
gene id: 573413:SPIRS_RS17920
uniprot id: E1R7D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS12985
gene id: 573413:SPIRS_RS12985
uniprot id: E1R4D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS09595
gene id: 573413:SPIRS_RS09595
uniprot id: E1R6K4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

573413:SPIRS RS09190
gene id: 573413:SPIRS_RS09190
uniprot id: E1R6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

573413:SPIRS RS15520
gene id: 573413:SPIRS_RS15520
uniprot id: E1R4T6
names: Similarity
messages: Belongs to the SufE family.

573413:SPIRS RS14845
gene id: 573413:SPIRS_RS14845
uniprot id: E1R3S1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

573413:SPIRS RS20025
gene id: 573413:SPIRS_RS20025
uniprot id: E1R990
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

573413:SPIRS RS12195
gene id: 573413:SPIRS_RS12195
uniprot id: E1R397
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

573413:SPIRS RS03845
gene id: 573413:SPIRS_RS03845
uniprot id: E1RC15
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

573413:SPIRS RS20045
gene id: 573413:SPIRS_RS20045
uniprot id: E1R994
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS20130
gene id: 573413:SPIRS_RS20130
uniprot id: E1R9B1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS17135
gene id: 573413:SPIRS_RS17135
uniprot id: E1R2C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS13570
gene id: 573413:SPIRS_RS13570
uniprot id: E1R8N7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

573413:SPIRS RS13170
gene id: 573413:SPIRS_RS13170
uniprot id: E1R4H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

573413:SPIRS RS16350
gene id: 573413:SPIRS_RS16350
uniprot id: E1R5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

573413:SPIRS RS21455
gene id: 573413:SPIRS_RS21455
uniprot id: E1RA20
names: Similarity
messages: Belongs to the ABC transporter superfamily.

573413:SPIRS RS16125
gene id: 573413:SPIRS_RS16125
uniprot id: E1R5G8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

573413:SPIRS RS11280
gene id: 573413:SPIRS_RS11280
uniprot id: E1R724
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

573413:SPIRS RS09110
gene id: 573413:SPIRS_RS09110
uniprot id: E1R6A8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

573413:SPIRS RS18580
gene id: 573413:SPIRS_RS18580
uniprot id: E1R7R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

573413:SPIRS RS13895
gene id: 573413:SPIRS_RS13895
uniprot id: E1R8V0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

573413:SPIRS RS02145
gene id: 573413:SPIRS_RS02145
uniprot id: E1RB43
names: Similarity
messages: Belongs to the DapA family.

573413:SPIRS RS11510
gene id: 573413:SPIRS_RS11510
uniprot id: E1R771
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS19525
gene id: 573413:SPIRS_RS19525
uniprot id: E1R8Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS04940
gene id: 573413:SPIRS_RS04940
uniprot id: E1RCN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

573413:SPIRS RS17725
gene id: 573413:SPIRS_RS17725
uniprot id: E1R796
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS15705
gene id: 573413:SPIRS_RS15705
uniprot id: E1R4X3
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

573413:SPIRS RS00160
gene id: 573413:SPIRS_RS00160
uniprot id: E1R6R1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573413:SPIRS RS20835
gene id: 573413:SPIRS_RS20835
uniprot id: E1R9Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

573413:SPIRS RS03650
gene id: 573413:SPIRS_RS03650
uniprot id: E1RBX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS21980
gene id: 573413:SPIRS_RS21980
uniprot id: E1R1F8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

573413:SPIRS RS06945
gene id: 573413:SPIRS_RS06945
uniprot id: E1R480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

573413:SPIRS RS15185
gene id: 573413:SPIRS_RS15185
uniprot id: E1R3Y8
names: Similarity
messages: Belongs to the P(II) protein family.

573413:SPIRS RS19970
gene id: 573413:SPIRS_RS19970
uniprot id: E1R979
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

573413:SPIRS RS07975
gene id: 573413:SPIRS_RS07975
uniprot id: E1R5T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

573413:SPIRS RS17610
gene id: 573413:SPIRS_RS17610
uniprot id: E1R2L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

573413:SPIRS RS05540
gene id: 573413:SPIRS_RS05540
uniprot id: E1R0Y2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

573413:SPIRS RS19710
gene id: 573413:SPIRS_RS19710
uniprot id: E1R927
names: Similarity
messages: Belongs to the glutamine synthetase family.

573413:SPIRS RS19070
gene id: 573413:SPIRS_RS19070
uniprot id: E1R813
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS09600
gene id: 573413:SPIRS_RS09600
uniprot id: E1R6K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

573413:SPIRS RS14465
gene id: 573413:SPIRS_RS14465
uniprot id: E1R282
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

573413:SPIRS RS03715
gene id: 573413:SPIRS_RS03715
uniprot id: E1RBY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS21000
gene id: 573413:SPIRS_RS21000
uniprot id: E1R9T3
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

573413:SPIRS RS13060
gene id: 573413:SPIRS_RS13060
uniprot id: E1R4F5
names: Subcellular Location Annotation
messages: Periplasmic flagellum

573413:SPIRS RS20210
gene id: 573413:SPIRS_RS20210
uniprot id: E1R9C6
names: Similarity
messages: Belongs to the peptidase S49 family.

573413:SPIRS RS02985
gene id: 573413:SPIRS_RS02985
uniprot id: E1RBK4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

573413:SPIRS RS20245
gene id: 573413:SPIRS_RS20245
uniprot id: E1R9D3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

573413:SPIRS RS14470
gene id: 573413:SPIRS_RS14470
uniprot id: E1R283
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

573413:SPIRS RS09120
gene id: 573413:SPIRS_RS09120
uniprot id: E1R6B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

573413:SPIRS RS14950
gene id: 573413:SPIRS_RS14950
uniprot id: E1R3U1
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

573413:SPIRS RS04095
gene id: 573413:SPIRS_RS04095
uniprot id: E1RC66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS07860
gene id: 573413:SPIRS_RS07860
uniprot id: E1R5R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

573413:SPIRS RS14490
gene id: 573413:SPIRS_RS14490
uniprot id: E1R287
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS15910
gene id: 573413:SPIRS_RS15910
uniprot id: E1R5C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS07475
gene id: 573413:SPIRS_RS07475
uniprot id: E1R573
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573413:SPIRS RS14945
gene id: 573413:SPIRS_RS14945
uniprot id: E1R3U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS13115
gene id: 573413:SPIRS_RS13115
uniprot id: E1R4G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

573413:SPIRS RS16150
gene id: 573413:SPIRS_RS16150
uniprot id: E1R5H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

573413:SPIRS RS13225
gene id: 573413:SPIRS_RS13225
uniprot id: E1R4I8
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

573413:SPIRS RS15975
gene id: 573413:SPIRS_RS15975
uniprot id: E1R5D7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

573413:SPIRS RS04870
gene id: 573413:SPIRS_RS04870
uniprot id: E1RCL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

573413:SPIRS RS11720
gene id: 573413:SPIRS_RS11720
uniprot id: E1R1R2
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS18250
gene id: 573413:SPIRS_RS18250
uniprot id: E1R7J9
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS00010
gene id: 573413:SPIRS_RS00010
uniprot id: E1R6N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

573413:SPIRS RS05225
gene id: 573413:SPIRS_RS05225
uniprot id: E1RCT9
names: Similarity
messages: Belongs to the hemerythrin family.

573413:SPIRS RS01440
gene id: 573413:SPIRS_RS01440
uniprot id: E1RAF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

573413:SPIRS RS17550
gene id: 573413:SPIRS_RS17550
uniprot id: E1R2K6
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS00180
gene id: 573413:SPIRS_RS00180
uniprot id: E1R6R5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573413:SPIRS RS16675
gene id: 573413:SPIRS_RS16675
uniprot id: E1RAN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS12400
gene id: 573413:SPIRS_RS12400
uniprot id: E1R3D8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS18175
gene id: 573413:SPIRS_RS18175
uniprot id: E1R7I5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

573413:SPIRS RS12150
gene id: 573413:SPIRS_RS12150
uniprot id: E1R1Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS18545
gene id: 573413:SPIRS_RS18545
uniprot id: E1R7Q7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

573413:SPIRS RS06255
gene id: 573413:SPIRS_RS06255
uniprot id: E1R2T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

573413:SPIRS RS11355
gene id: 573413:SPIRS_RS11355
uniprot id: E1R740
names: Similarity
messages: Belongs to the UPF0178 family.

573413:SPIRS RS06855
gene id: 573413:SPIRS_RS06855
uniprot id: E1R462
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS20695
gene id: 573413:SPIRS_RS20695
uniprot id: E1R9M3
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS19550
gene id: 573413:SPIRS_RS19550
uniprot id: E1R8Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

573413:SPIRS RS02770
gene id: 573413:SPIRS_RS02770
uniprot id: E1RBG0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

573413:SPIRS RS04580
gene id: 573413:SPIRS_RS04580
uniprot id: E1RCG0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

573413:SPIRS RS04800
gene id: 573413:SPIRS_RS04800
uniprot id: E1RCK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

573413:SPIRS RS00005
gene id: 573413:SPIRS_RS00005
uniprot id: E1R6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

573413:SPIRS RS19760
gene id: 573413:SPIRS_RS19760
uniprot id: E1R937
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS14780
gene id: 573413:SPIRS_RS14780
uniprot id: E1R3Q8
names: Subcellular Location Annotation
messages: Periplasmic flagellum

573413:SPIRS RS03375
gene id: 573413:SPIRS_RS03375
uniprot id: E1RBS6
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

573413:SPIRS RS02825
gene id: 573413:SPIRS_RS02825
uniprot id: E1RBH1
names: Similarity
messages: Belongs to the BMP lipoprotein family.

573413:SPIRS RS01790
gene id: 573413:SPIRS_RS01790
uniprot id: E1RAY0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

573413:SPIRS RS04640
gene id: 573413:SPIRS_RS04640
uniprot id: E1RCH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS11370
gene id: 573413:SPIRS_RS11370
uniprot id: E1R743
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

573413:SPIRS RS18095
gene id: 573413:SPIRS_RS18095
uniprot id: E1R7G9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

573413:SPIRS RS01070
gene id: 573413:SPIRS_RS01070
uniprot id: E1RA77
names: Similarity
messages: Belongs to the peptidase M24B family.

573413:SPIRS RS04950
gene id: 573413:SPIRS_RS04950
uniprot id: E1RCN4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

573413:SPIRS RS00120
gene id: 573413:SPIRS_RS00120
uniprot id: E1R6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS06670
gene id: 573413:SPIRS_RS06670
uniprot id: E1R425
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

573413:SPIRS RS05370
gene id: 573413:SPIRS_RS05370
uniprot id: E1R0U9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

573413:SPIRS RS07185
gene id: 573413:SPIRS_RS07185
uniprot id: E1R515
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

573413:SPIRS RS14165
gene id: 573413:SPIRS_RS14165
uniprot id: E1R221
names: Subcellular Location Annotation
messages: Virion

573413:SPIRS RS18190
gene id: 573413:SPIRS_RS18190
uniprot id: E1R7I8
names: Subcellular Location Annotation
messages: Cytoplasm

573413:SPIRS RS11985
gene id: 573413:SPIRS_RS11985
uniprot id: E1R1W4
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS17005
gene id: 573413:SPIRS_RS17005
uniprot id: E1RAU3
names: Similarity
messages: Belongs to the DapA family.

573413:SPIRS RS11330
gene id: 573413:SPIRS_RS11330
uniprot id: E1R735
names: Similarity
messages: Belongs to the ArsC family.

573413:SPIRS RS19410
gene id: 573413:SPIRS_RS19410
uniprot id: E1R882
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS14585
gene id: 573413:SPIRS_RS14585
uniprot id: E1R3M0
names: Similarity
messages: Belongs to the FemABX family.

573413:SPIRS RS16660
gene id: 573413:SPIRS_RS16660
uniprot id: E1RAM8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS16395
gene id: 573413:SPIRS_RS16395
uniprot id: E1R5L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS19660
gene id: 573413:SPIRS_RS19660
uniprot id: E1R917
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

573413:SPIRS RS09610
gene id: 573413:SPIRS_RS09610
uniprot id: E1R6K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

573413:SPIRS RS00605
gene id: 573413:SPIRS_RS00605
uniprot id: E1R8D2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

573413:SPIRS RS04540
gene id: 573413:SPIRS_RS04540
uniprot id: E1RCF2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

573413:SPIRS RS16005
gene id: 573413:SPIRS_RS16005
uniprot id: E1R5E4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

573413:SPIRS RS20315
gene id: 573413:SPIRS_RS20315
uniprot id: E1R9E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573413:SPIRS RS02805
gene id: 573413:SPIRS_RS02805
uniprot id: E1RBG7
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

573413:SPIRS RS20330
gene id: 573413:SPIRS_RS20330
uniprot id: E1R9F0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

573413:SPIRS RS18925
gene id: 573413:SPIRS_RS18925
uniprot id: E1R7Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

573413:SPIRS RS02990
gene id: 573413:SPIRS_RS02990
uniprot id: E1RBK5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

573413:SPIRS RS00240
gene id: 573413:SPIRS_RS00240
uniprot id: E1R6S7
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS05715
gene id: 573413:SPIRS_RS05715
uniprot id: E1R116
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

573413:SPIRS RS07365
gene id: 573413:SPIRS_RS07365
uniprot id: E1R551
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

573413:SPIRS RS01290
gene id: 573413:SPIRS_RS01290
uniprot id: E1RAC0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573413:SPIRS RS02930
gene id: 573413:SPIRS_RS02930
uniprot id: E1RBJ2
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

573413:SPIRS RS04185
gene id: 573413:SPIRS_RS04185
uniprot id: E1RC85
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS14645
gene id: 573413:SPIRS_RS14645
uniprot id: E1R3N2
names: Similarity
messages: Belongs to the peptidase C40 family.

573413:SPIRS RS11745
gene id: 573413:SPIRS_RS11745
uniprot id: E1R1R7
names: Similarity
messages: Belongs to the DEAD box helicase family.

573413:SPIRS RS07955
gene id: 573413:SPIRS_RS07955
uniprot id: E1R5T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

573413:SPIRS RS06180
gene id: 573413:SPIRS_RS06180
uniprot id: E1R2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS19055
gene id: 573413:SPIRS_RS19055
uniprot id: E1R810
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

573413:SPIRS RS15240
gene id: 573413:SPIRS_RS15240
uniprot id: E1R4N2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two zinc ions.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

573413:SPIRS RS18850
gene id: 573413:SPIRS_RS18850
uniprot id: E1R7W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

573413:SPIRS RS09685
gene id: 573413:SPIRS_RS09685
uniprot id: E1R6M2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

573413:SPIRS RS20715
gene id: 573413:SPIRS_RS20715
uniprot id: E1R9M6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

573413:SPIRS RS07985
gene id: 573413:SPIRS_RS07985
uniprot id: E1R5U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

573413:SPIRS RS15085
gene id: 573413:SPIRS_RS15085
uniprot id: E1R3W8
names: Similarity
messages: Belongs to the TPP enzyme family.

573413:SPIRS RS14820
gene id: 573413:SPIRS_RS14820
uniprot id: E1R3R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

573413:SPIRS RS01455
gene id: 573413:SPIRS_RS01455
uniprot id: E1RAF3
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS13625
gene id: 573413:SPIRS_RS13625
uniprot id: E1R8P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.
messages: Cytoplasm

573413:SPIRS RS17255
gene id: 573413:SPIRS_RS17255
uniprot id: E1R2E8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS04525
gene id: 573413:SPIRS_RS04525
uniprot id: E1RCE9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

573413:SPIRS RS10285
gene id: 573413:SPIRS_RS10285
uniprot id: E1R1L6
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS04230
gene id: 573413:SPIRS_RS04230
uniprot id: E1RC94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS02885
gene id: 573413:SPIRS_RS02885
uniprot id: E1RBI3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS04775
gene id: 573413:SPIRS_RS04775
uniprot id: E1RCJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

573413:SPIRS RS13750
gene id: 573413:SPIRS_RS13750
uniprot id: E1R8S3
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS20570
gene id: 573413:SPIRS_RS20570
uniprot id: E1R9J7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

573413:SPIRS RS14515
gene id: 573413:SPIRS_RS14515
uniprot id: E1R292
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

573413:SPIRS RS01740
gene id: 573413:SPIRS_RS01740
uniprot id: E1RAX0
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS16120
gene id: 573413:SPIRS_RS16120
uniprot id: E1R5G7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

573413:SPIRS RS03830
gene id: 573413:SPIRS_RS03830
uniprot id: E1RC12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

573413:SPIRS RS03210
gene id: 573413:SPIRS_RS03210
uniprot id: E1RBP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS15990
gene id: 573413:SPIRS_RS15990
uniprot id: E1R5E0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

573413:SPIRS RS09040
gene id: 573413:SPIRS_RS09040
uniprot id: E1R194
names: Similarity
messages: Belongs to the phosphohexose mutase family.

573413:SPIRS RS04605
gene id: 573413:SPIRS_RS04605
uniprot id: E1RCG5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily.

573413:SPIRS RS07305
gene id: 573413:SPIRS_RS07305
uniprot id: E1R539
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573413:SPIRS RS19440
gene id: 573413:SPIRS_RS19440
uniprot id: E1R888
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

573413:SPIRS RS09675
gene id: 573413:SPIRS_RS09675
uniprot id: E1R6M0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

573413:SPIRS RS15950
gene id: 573413:SPIRS_RS15950
uniprot id: E1R5D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS15680
gene id: 573413:SPIRS_RS15680
uniprot id: E1R4W8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

573413:SPIRS RS11785
gene id: 573413:SPIRS_RS11785
uniprot id: E1R1S5
names: Similarity
messages: Belongs to the aldose epimerase family.

573413:SPIRS RS13810
gene id: 573413:SPIRS_RS13810
uniprot id: E1R8T3
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

573413:SPIRS RS21560
gene id: 573413:SPIRS_RS21560
uniprot id: E1RA40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

573413:SPIRS RS21620
gene id: 573413:SPIRS_RS21620
uniprot id: E1RA52
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

573413:SPIRS RS08365
gene id: 573413:SPIRS_RS08365
uniprot id: E1R617
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

573413:SPIRS RS18100
gene id: 573413:SPIRS_RS18100
uniprot id: E1R7H0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

573413:SPIRS RS08700
gene id: 573413:SPIRS_RS08700
uniprot id: E1R683
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

573413:SPIRS RS08385
gene id: 573413:SPIRS_RS08385
uniprot id: E1R620
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS01210
gene id: 573413:SPIRS_RS01210
uniprot id: E1RAA5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

573413:SPIRS RS17755
gene id: 573413:SPIRS_RS17755
uniprot id: E1R7A2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

573413:SPIRS RS17580
gene id: 573413:SPIRS_RS17580
uniprot id: E1R2L2
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

573413:SPIRS RS16385
gene id: 573413:SPIRS_RS16385
uniprot id: E1R5L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

573413:SPIRS RS18055
gene id: 573413:SPIRS_RS18055
uniprot id: E1R7G1
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS01820
gene id: 573413:SPIRS_RS01820
uniprot id: E1RAY6
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS05430
gene id: 573413:SPIRS_RS05430
uniprot id: E1R0W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

573413:SPIRS RS17750
gene id: 573413:SPIRS_RS17750
uniprot id: E1R7A1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS10445
gene id: 573413:SPIRS_RS10445
uniprot id: E1R303
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS06240
gene id: 573413:SPIRS_RS06240
uniprot id: E1R2T5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

573413:SPIRS RS13345
gene id: 573413:SPIRS_RS13345
uniprot id: E1R4L0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

573413:SPIRS RS05260
gene id: 573413:SPIRS_RS05260
uniprot id: E1RCU6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

573413:SPIRS RS04885
gene id: 573413:SPIRS_RS04885
uniprot id: E1RCL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

573413:SPIRS RS18690
gene id: 573413:SPIRS_RS18690
uniprot id: E1R7T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS03175
gene id: 573413:SPIRS_RS03175
uniprot id: E1RBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS02610
gene id: 573413:SPIRS_RS02610
uniprot id: E1RBD0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573413:SPIRS RS11570
gene id: 573413:SPIRS_RS11570
uniprot id: E1R1N4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

573413:SPIRS RS05760
gene id: 573413:SPIRS_RS05760
uniprot id: E1R125
names: Similarity
messages: Belongs to the AOR/FOR family.

573413:SPIRS RS13385
gene id: 573413:SPIRS_RS13385
uniprot id: E1R4L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573413:SPIRS RS21520
gene id: 573413:SPIRS_RS21520
uniprot id: E1RA32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

573413:SPIRS RS16360
gene id: 573413:SPIRS_RS16360
uniprot id: E1R5L0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

573413:SPIRS RS11495
gene id: 573413:SPIRS_RS11495
uniprot id: E1R768
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

573413:SPIRS RS00460
gene id: 573413:SPIRS_RS00460
uniprot id: E1R8A5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

573413:SPIRS RS06215
gene id: 573413:SPIRS_RS06215
uniprot id: E1R2T0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

573413:SPIRS RS04720
gene id: 573413:SPIRS_RS04720
uniprot id: E1RCI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS01630
gene id: 573413:SPIRS_RS01630
uniprot id: E1RAU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

573413:SPIRS RS03730
gene id: 573413:SPIRS_RS03730
uniprot id: E1RBZ2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

573413:SPIRS RS09670
gene id: 573413:SPIRS_RS09670
uniprot id: E1R6L9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

573413:SPIRS RS17390
gene id: 573413:SPIRS_RS17390
uniprot id: E1R2H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS01575
gene id: 573413:SPIRS_RS01575
uniprot id: E1RAH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS06525
gene id: 573413:SPIRS_RS06525
uniprot id: E1R401
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

573413:SPIRS RS09575
gene id: 573413:SPIRS_RS09575
uniprot id: E1R6K0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS09475
gene id: 573413:SPIRS_RS09475
uniprot id: E1R6H9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

573413:SPIRS RS09290
gene id: 573413:SPIRS_RS09290
uniprot id: E1R6E3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

573413:SPIRS RS18225
gene id: 573413:SPIRS_RS18225
uniprot id: E1R7J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

573413:SPIRS RS02725
gene id: 573413:SPIRS_RS02725
uniprot id: E1RBF3
names: Similarity
messages: Belongs to the peptidase C56 family.

573413:SPIRS RS17635
gene id: 573413:SPIRS_RS17635
uniprot id: E1R778
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS01590
gene id: 573413:SPIRS_RS01590
uniprot id: E1RAI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

573413:SPIRS RS19305
gene id: 573413:SPIRS_RS19305
uniprot id: E1R861
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS10820
gene id: 573413:SPIRS_RS10820
uniprot id: E1R375
names: Similarity
messages: Belongs to the RecJ family.

573413:SPIRS RS07045
gene id: 573413:SPIRS_RS07045
uniprot id: E1R4A0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

573413:SPIRS RS21210
gene id: 573413:SPIRS_RS21210
uniprot id: E1R9X3
names: Subunit
messages: Homodimer.

573413:SPIRS RS17890
gene id: 573413:SPIRS_RS17890
uniprot id: E1R7C9
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

573413:SPIRS RS09450
gene id: 573413:SPIRS_RS09450
uniprot id: E1R6H4
names: Subcellular Location Annotation
messages: Nucleus

573413:SPIRS RS06160
gene id: 573413:SPIRS_RS06160
uniprot id: E1R2R9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

573413:SPIRS RS14915
gene id: 573413:SPIRS_RS14915
uniprot id: E1R3T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

573413:SPIRS RS18940
gene id: 573413:SPIRS_RS18940
uniprot id: E1R7Y8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

573413:SPIRS RS15165
gene id: 573413:SPIRS_RS15165
uniprot id: E1R3Y4
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

573413:SPIRS RS16055
gene id: 573413:SPIRS_RS16055
uniprot id: E1R5F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS12105
gene id: 573413:SPIRS_RS12105
uniprot id: E1R1Y4
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS19855
gene id: 573413:SPIRS_RS19855
uniprot id: E1R956
names: Similarity
messages: Belongs to the threonine aldolase family.

573413:SPIRS RS08860
gene id: 573413:SPIRS_RS08860
uniprot id: E1R159
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

573413:SPIRS RS14565
gene id: 573413:SPIRS_RS14565
uniprot id: E1R3L6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

573413:SPIRS RS16795
gene id: 573413:SPIRS_RS16795
uniprot id: E1RAQ5
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

573413:SPIRS RS13965
gene id: 573413:SPIRS_RS13965
uniprot id: E1R8W3
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS13785
gene id: 573413:SPIRS_RS13785
uniprot id: E1R8S8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

573413:SPIRS RS00430
gene id: 573413:SPIRS_RS00430
uniprot id: E1R8A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

573413:SPIRS RS15210
gene id: 573413:SPIRS_RS15210
uniprot id: E1R4M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

573413:SPIRS RS16475
gene id: 573413:SPIRS_RS16475
uniprot id: E1RAJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS12340
gene id: 573413:SPIRS_RS12340
uniprot id: E1R3C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

573413:SPIRS RS06810
gene id: 573413:SPIRS_RS06810
uniprot id: E1R453
names: Similarity
messages: Belongs to the DapA family.

573413:SPIRS RS21200
gene id: 573413:SPIRS_RS21200
uniprot id: E1R9X1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

573413:SPIRS RS01745
gene id: 573413:SPIRS_RS01745
uniprot id: E1RAX1
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS07520
gene id: 573413:SPIRS_RS07520
uniprot id: E1R582
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

573413:SPIRS RS18530
gene id: 573413:SPIRS_RS18530
uniprot id: E1R7Q4
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS07375
gene id: 573413:SPIRS_RS07375
uniprot id: E1R553
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

573413:SPIRS RS04755
gene id: 573413:SPIRS_RS04755
uniprot id: E1RCJ5
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

573413:SPIRS RS09730
gene id: 573413:SPIRS_RS09730
uniprot id: E1R1A8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS03870
gene id: 573413:SPIRS_RS03870
uniprot id: E1RC20
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

573413:SPIRS RS14020
gene id: 573413:SPIRS_RS14020
uniprot id: E1R8X4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

573413:SPIRS RS14615
gene id: 573413:SPIRS_RS14615
uniprot id: E1R3M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

573413:SPIRS RS00420
gene id: 573413:SPIRS_RS00420
uniprot id: E1R8A2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

573413:SPIRS RS08380
gene id: 573413:SPIRS_RS08380
uniprot id: E1R619
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS03985
gene id: 573413:SPIRS_RS03985
uniprot id: E1RC44
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

573413:SPIRS RS05025
gene id: 573413:SPIRS_RS05025
uniprot id: E1RCP9
names: Similarity
messages: Belongs to the FGGY kinase family.

573413:SPIRS RS11160
gene id: 573413:SPIRS_RS11160
uniprot id: E1R700
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

573413:SPIRS RS11125
gene id: 573413:SPIRS_RS11125
uniprot id: E1R6Z2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

573413:SPIRS RS14675
gene id: 573413:SPIRS_RS14675
uniprot id: E1R3N8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

573413:SPIRS RS19340
gene id: 573413:SPIRS_RS19340
uniprot id: E1R868
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

573413:SPIRS RS12945
gene id: 573413:SPIRS_RS12945
uniprot id: E1R4D1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

573413:SPIRS RS12990
gene id: 573413:SPIRS_RS12990
uniprot id: E1R4E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS01865
gene id: 573413:SPIRS_RS01865
uniprot id: E1RAZ5
names: Similarity
messages: Belongs to the peptidase M29 family.

573413:SPIRS RS19270
gene id: 573413:SPIRS_RS19270
uniprot id: E1R854
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

573413:SPIRS RS01330
gene id: 573413:SPIRS_RS01330
uniprot id: E1RAC8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS09485
gene id: 573413:SPIRS_RS09485
uniprot id: E1R6I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

573413:SPIRS RS21760
gene id: 573413:SPIRS_RS21760
uniprot id: E1R1G9
names: Similarity
messages: Belongs to the peptidase S14 family.

573413:SPIRS RS11155
gene id: 573413:SPIRS_RS11155
uniprot id: E1R6Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

573413:SPIRS RS03060
gene id: 573413:SPIRS_RS03060
uniprot id: E1RBL8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

573413:SPIRS RS08525
gene id: 573413:SPIRS_RS08525
uniprot id: E1R648
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

573413:SPIRS RS18990
gene id: 573413:SPIRS_RS18990
uniprot id: E1R7Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS14600
gene id: 573413:SPIRS_RS14600
uniprot id: E1R3M3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

573413:SPIRS RS04860
gene id: 573413:SPIRS_RS04860
uniprot id: E1RCL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

573413:SPIRS RS07795
gene id: 573413:SPIRS_RS07795
uniprot id: E1R5Q2
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

573413:SPIRS RS19605
gene id: 573413:SPIRS_RS19605
uniprot id: E1R906
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS15290
gene id: 573413:SPIRS_RS15290
uniprot id: E1R4P2
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS16925
gene id: 573413:SPIRS_RS16925
uniprot id: E1RAS9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

573413:SPIRS RS19755
gene id: 573413:SPIRS_RS19755
uniprot id: E1R936
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

573413:SPIRS RS11435
gene id: 573413:SPIRS_RS11435
uniprot id: E1R756
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

573413:SPIRS RS03460
gene id: 573413:SPIRS_RS03460
uniprot id: E1RBU2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

573413:SPIRS RS04065
gene id: 573413:SPIRS_RS04065
uniprot id: E1RC60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS04900
gene id: 573413:SPIRS_RS04900
uniprot id: E1RCM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

573413:SPIRS RS17710
gene id: 573413:SPIRS_RS17710
uniprot id: E1R793
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

573413:SPIRS RS11360
gene id: 573413:SPIRS_RS11360
uniprot id: E1R741
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

573413:SPIRS RS08320
gene id: 573413:SPIRS_RS08320
uniprot id: E1R608
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS19020
gene id: 573413:SPIRS_RS19020
uniprot id: E1R803
names: Similarity
messages: Belongs to the P(II) protein family.

573413:SPIRS RS00775
gene id: 573413:SPIRS_RS00775
uniprot id: E1R8G6
names: Similarity
messages: Belongs to the peptidase S41A family.

573413:SPIRS RS09345
gene id: 573413:SPIRS_RS09345
uniprot id: E1R6F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS04415
gene id: 573413:SPIRS_RS04415
uniprot id: E1RCC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

573413:SPIRS RS17095
gene id: 573413:SPIRS_RS17095
uniprot id: E1R2B9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

573413:SPIRS RS18120
gene id: 573413:SPIRS_RS18120
uniprot id: E1R7H4
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS06470
gene id: 573413:SPIRS_RS06470
uniprot id: E1R3Z1
names: Similarity
messages: Belongs to the BMP lipoprotein family.

573413:SPIRS RS05375
gene id: 573413:SPIRS_RS05375
uniprot id: E1R0V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

573413:SPIRS RS18945
gene id: 573413:SPIRS_RS18945
uniprot id: E1R7Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

573413:SPIRS RS05820
gene id: 573413:SPIRS_RS05820
uniprot id: E1R137
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS17545
gene id: 573413:SPIRS_RS17545
uniprot id: E1R2K5
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS20770
gene id: 573413:SPIRS_RS20770
uniprot id: E1R9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

573413:SPIRS RS00690
gene id: 573413:SPIRS_RS00690
uniprot id: E1R8E9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS18585
gene id: 573413:SPIRS_RS18585
uniprot id: E1R7R6
names: Similarity
messages: Belongs to the glutaminase PdxT/SNO family.

573413:SPIRS RS06395
gene id: 573413:SPIRS_RS06395
uniprot id: E1R2W6
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS10710
gene id: 573413:SPIRS_RS10710
uniprot id: E1R353
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573413:SPIRS RS07200
gene id: 573413:SPIRS_RS07200
uniprot id: E1R518
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS11015
gene id: 573413:SPIRS_RS11015
uniprot id: E1R6X0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

573413:SPIRS RS04435
gene id: 573413:SPIRS_RS04435
uniprot id: E1RCD1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

573413:SPIRS RS19890
gene id: 573413:SPIRS_RS19890
uniprot id: E1R963
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573413:SPIRS RS16780
gene id: 573413:SPIRS_RS16780
uniprot id: E1RAQ2
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS15400
gene id: 573413:SPIRS_RS15400
uniprot id: E1R4R4
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

573413:SPIRS RS09580
gene id: 573413:SPIRS_RS09580
uniprot id: E1R6K1
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

573413:SPIRS RS21215
gene id: 573413:SPIRS_RS21215
uniprot id: E1R9X4
names: Similarity
messages: Belongs to the UPF0047 family.

573413:SPIRS RS21230
gene id: 573413:SPIRS_RS21230
uniprot id: E1R9X7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

573413:SPIRS RS20260
gene id: 573413:SPIRS_RS20260
uniprot id: E1R9D6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

573413:SPIRS RS09175
gene id: 573413:SPIRS_RS09175
uniprot id: E1R6C1
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

573413:SPIRS RS17350
gene id: 573413:SPIRS_RS17350
uniprot id: E1R2G7
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

573413:SPIRS RS00590
gene id: 573413:SPIRS_RS00590
uniprot id: E1R8C9
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

573413:SPIRS RS00870
gene id: 573413:SPIRS_RS00870
uniprot id: E1R8I5
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

573413:SPIRS RS01655
gene id: 573413:SPIRS_RS01655
uniprot id: E1RAV3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

573413:SPIRS RS14665
gene id: 573413:SPIRS_RS14665
uniprot id: E1R3N6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

573413:SPIRS RS11190
gene id: 573413:SPIRS_RS11190
uniprot id: E1R706
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS11565
gene id: 573413:SPIRS_RS11565
uniprot id: E1R1N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

573413:SPIRS RS00765
gene id: 573413:SPIRS_RS00765
uniprot id: E1R8G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

573413:SPIRS RS08565
gene id: 573413:SPIRS_RS08565
uniprot id: E1R656
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS06040
gene id: 573413:SPIRS_RS06040
uniprot id: E1R2P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS09570
gene id: 573413:SPIRS_RS09570
uniprot id: E1R6J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

573413:SPIRS RS01255
gene id: 573413:SPIRS_RS01255
uniprot id: E1RAB3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

573413:SPIRS RS07830
gene id: 573413:SPIRS_RS07830
uniprot id: E1R5Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

573413:SPIRS RS02170
gene id: 573413:SPIRS_RS02170
uniprot id: E1RB48
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

573413:SPIRS RS05405
gene id: 573413:SPIRS_RS05405
uniprot id: E1R0V7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

573413:SPIRS RS18600
gene id: 573413:SPIRS_RS18600
uniprot id: E1R7R9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

573413:SPIRS RS03370
gene id: 573413:SPIRS_RS03370
uniprot id: E1RBS5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

573413:SPIRS RS05950
gene id: 573413:SPIRS_RS05950
uniprot id: E1R2M9
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS15370
gene id: 573413:SPIRS_RS15370
uniprot id: E1R4Q8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

573413:SPIRS RS21490
gene id: 573413:SPIRS_RS21490
uniprot id: E1RA26
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

573413:SPIRS RS14495
gene id: 573413:SPIRS_RS14495
uniprot id: E1R288
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

573413:SPIRS RS14595
gene id: 573413:SPIRS_RS14595
uniprot id: E1R3M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

573413:SPIRS RS14850
gene id: 573413:SPIRS_RS14850
uniprot id: E1R3S2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

573413:SPIRS RS03215
gene id: 573413:SPIRS_RS03215
uniprot id: E1RBP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS00710
gene id: 573413:SPIRS_RS00710
uniprot id: E1R8F3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

573413:SPIRS RS03410
gene id: 573413:SPIRS_RS03410
uniprot id: E1RBT2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

573413:SPIRS RS03890
gene id: 573413:SPIRS_RS03890
uniprot id: E1RC25
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

573413:SPIRS RS00040
gene id: 573413:SPIRS_RS00040
uniprot id: E1R6N7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS20580
gene id: 573413:SPIRS_RS20580
uniprot id: E1R9J9
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS11490
gene id: 573413:SPIRS_RS11490
uniprot id: E1R767
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

573413:SPIRS RS13120
gene id: 573413:SPIRS_RS13120
uniprot id: E1R4G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

573413:SPIRS RS16525
gene id: 573413:SPIRS_RS16525
uniprot id: E1RAK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

573413:SPIRS RS00150
gene id: 573413:SPIRS_RS00150
uniprot id: E1R6Q9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

573413:SPIRS RS03760
gene id: 573413:SPIRS_RS03760
uniprot id: E1RBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS00095
gene id: 573413:SPIRS_RS00095
uniprot id: E1R6P8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

573413:SPIRS RS08825
gene id: 573413:SPIRS_RS08825
uniprot id: E1R6A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

573413:SPIRS RS16740
gene id: 573413:SPIRS_RS16740
uniprot id: E1RAP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

573413:SPIRS RS09585
gene id: 573413:SPIRS_RS09585
uniprot id: E1R6K2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

573413:SPIRS RS05070
gene id: 573413:SPIRS_RS05070
uniprot id: E1RCQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS04845
gene id: 573413:SPIRS_RS04845
uniprot id: E1RCL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

573413:SPIRS RS09500
gene id: 573413:SPIRS_RS09500
uniprot id: E1R6I4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

573413:SPIRS RS03935
gene id: 573413:SPIRS_RS03935
uniprot id: E1RC34
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

573413:SPIRS RS13410
gene id: 573413:SPIRS_RS13410
uniprot id: E1R4M1
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

573413:SPIRS RS12345
gene id: 573413:SPIRS_RS12345
uniprot id: E1R3C7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

573413:SPIRS RS11140
gene id: 573413:SPIRS_RS11140
uniprot id: E1R6Z6
names: Similarity
messages: Belongs to the CitG/MdcB family.

573413:SPIRS RS11135
gene id: 573413:SPIRS_RS11135
uniprot id: E1R6Z5
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

573413:SPIRS RS20265
gene id: 573413:SPIRS_RS20265
uniprot id: E1R9D7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573413:SPIRS RS20305
gene id: 573413:SPIRS_RS20305
uniprot id: E1R9E6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

573413:SPIRS RS09640
gene id: 573413:SPIRS_RS09640
uniprot id: E1R6L3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

573413:SPIRS RS01080
gene id: 573413:SPIRS_RS01080
uniprot id: E1RA79
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

573413:SPIRS RS08625
gene id: 573413:SPIRS_RS08625
uniprot id: E1R668
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS15850
gene id: 573413:SPIRS_RS15850
uniprot id: E1R5B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

573413:SPIRS RS14475
gene id: 573413:SPIRS_RS14475
uniprot id: E1R284
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

573413:SPIRS RS07060
gene id: 573413:SPIRS_RS07060
uniprot id: E1R4A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS05625
gene id: 573413:SPIRS_RS05625
uniprot id: E1R0Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

573413:SPIRS RS08540
gene id: 573413:SPIRS_RS08540
uniprot id: E1R651
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

573413:SPIRS RS02165
gene id: 573413:SPIRS_RS02165
uniprot id: E1RB47
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

573413:SPIRS RS15920
gene id: 573413:SPIRS_RS15920
uniprot id: E1R5C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573413:SPIRS RS08085
gene id: 573413:SPIRS_RS08085
uniprot id: E1R5W0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

573413:SPIRS RS12320
gene id: 573413:SPIRS_RS12320
uniprot id: E1R3C2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

573413:SPIRS RS16680
gene id: 573413:SPIRS_RS16680
uniprot id: E1RAN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS13805
gene id: 573413:SPIRS_RS13805
uniprot id: E1R8T2
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

573413:SPIRS RS17330
gene id: 573413:SPIRS_RS17330
uniprot id: E1R2G3
names: Similarity
messages: Belongs to the universal stress protein A family.

573413:SPIRS RS20815
gene id: 573413:SPIRS_RS20815
uniprot id: E1R9P6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

573413:SPIRS RS02400
gene id: 573413:SPIRS_RS02400
uniprot id: E1RB90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

573413:SPIRS RS21315
gene id: 573413:SPIRS_RS21315
uniprot id: E1R9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

573413:SPIRS RS20995
gene id: 573413:SPIRS_RS20995
uniprot id: E1R9T2
names: Caution
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS12830
gene id: 573413:SPIRS_RS12830
uniprot id: E1R4B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

573413:SPIRS RS08280
gene id: 573413:SPIRS_RS08280
uniprot id: E1R600
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

573413:SPIRS RS21285
gene id: 573413:SPIRS_RS21285
uniprot id: E1R9Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

573413:SPIRS RS07290
gene id: 573413:SPIRS_RS07290
uniprot id: E1R536
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

573413:SPIRS RS07765
gene id: 573413:SPIRS_RS07765
uniprot id: E1R5P6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS14480
gene id: 573413:SPIRS_RS14480
uniprot id: E1R285
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

573413:SPIRS RS20235
gene id: 573413:SPIRS_RS20235
uniprot id: E1R9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

573413:SPIRS RS04625
gene id: 573413:SPIRS_RS04625
uniprot id: E1RCG9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

573413:SPIRS RS00290
gene id: 573413:SPIRS_RS00290
uniprot id: E1R6T7
names: Similarity
messages: Belongs to the pyruvate kinase family.

573413:SPIRS RS10835
gene id: 573413:SPIRS_RS10835
uniprot id: E1R378
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

573413:SPIRS RS21545
gene id: 573413:SPIRS_RS21545
uniprot id: E1RA37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

573413:SPIRS RS15395
gene id: 573413:SPIRS_RS15395
uniprot id: E1R4R3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

573413:SPIRS RS04515
gene id: 573413:SPIRS_RS04515
uniprot id: E1RCE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

573413:SPIRS RS03620
gene id: 573413:SPIRS_RS03620
uniprot id: E1RBX0
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS15450
gene id: 573413:SPIRS_RS15450
uniprot id: E1R4S3
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

573413:SPIRS RS08115
gene id: 573413:SPIRS_RS08115
uniprot id: E1R5W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

573413:SPIRS RS09765
gene id: 573413:SPIRS_RS09765
uniprot id: E1R1B5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

573413:SPIRS RS09020
gene id: 573413:SPIRS_RS09020
uniprot id: E1R190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS06060
gene id: 573413:SPIRS_RS06060
uniprot id: E1R2Q1
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS05800
gene id: 573413:SPIRS_RS05800
uniprot id: E1R133
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

573413:SPIRS RS21655
gene id: 573413:SPIRS_RS21655
uniprot id: E1RA59
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

573413:SPIRS RS00175
gene id: 573413:SPIRS_RS00175
uniprot id: E1R6R4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

573413:SPIRS RS06155
gene id: 573413:SPIRS_RS06155
uniprot id: E1R2R8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

573413:SPIRS RS06145
gene id: 573413:SPIRS_RS06145
uniprot id: E1R2R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS10195
gene id: 573413:SPIRS_RS10195
uniprot id: E1R1J8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

573413:SPIRS RS06425
gene id: 573413:SPIRS_RS06425
uniprot id: E1R2X2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

573413:SPIRS RS10725
gene id: 573413:SPIRS_RS10725
uniprot id: E1R356
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS19080
gene id: 573413:SPIRS_RS19080
uniprot id: E1R815
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS03090
gene id: 573413:SPIRS_RS03090
uniprot id: E1RBM2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

573413:SPIRS RS16340
gene id: 573413:SPIRS_RS16340
uniprot id: E1R5K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

573413:SPIRS RS08675
gene id: 573413:SPIRS_RS08675
uniprot id: E1R678
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

573413:SPIRS RS09555
gene id: 573413:SPIRS_RS09555
uniprot id: E1R6J6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

573413:SPIRS RS07925
gene id: 573413:SPIRS_RS07925
uniprot id: E1R5S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS13150
gene id: 573413:SPIRS_RS13150
uniprot id: E1R4H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

573413:SPIRS RS18555
gene id: 573413:SPIRS_RS18555
uniprot id: E1R7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

573413:SPIRS RS13000
gene id: 573413:SPIRS_RS13000
uniprot id: E1R4E3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

573413:SPIRS RS18460
gene id: 573413:SPIRS_RS18460
uniprot id: E1R7P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

573413:SPIRS RS06200
gene id: 573413:SPIRS_RS06200
uniprot id: E1R2S7
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

573413:SPIRS RS07965
gene id: 573413:SPIRS_RS07965
uniprot id: E1R5T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

573413:SPIRS RS10570
gene id: 573413:SPIRS_RS10570
uniprot id: E1R325
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS07190
gene id: 573413:SPIRS_RS07190
uniprot id: E1R516
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS08255
gene id: 573413:SPIRS_RS08255
uniprot id: E1R5Z5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

573413:SPIRS RS08905
gene id: 573413:SPIRS_RS08905
uniprot id: E1R168
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

573413:SPIRS RS12475
gene id: 573413:SPIRS_RS12475
uniprot id: E1R3F3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

573413:SPIRS RS14660
gene id: 573413:SPIRS_RS14660
uniprot id: E1R3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

573413:SPIRS RS16180
gene id: 573413:SPIRS_RS16180
uniprot id: E1R5H9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

573413:SPIRS RS10790
gene id: 573413:SPIRS_RS10790
uniprot id: E1R369
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

573413:SPIRS RS06435
gene id: 573413:SPIRS_RS06435
uniprot id: E1R2X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS03380
gene id: 573413:SPIRS_RS03380
uniprot id: E1RBS7
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS01620
gene id: 573413:SPIRS_RS01620
uniprot id: E1RAU7
names: Similarity
messages: Belongs to the peptidase S16 family.

573413:SPIRS RS09490
gene id: 573413:SPIRS_RS09490
uniprot id: E1R6I2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

573413:SPIRS RS17720
gene id: 573413:SPIRS_RS17720
uniprot id: E1R795
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS07770
gene id: 573413:SPIRS_RS07770
uniprot id: E1R5P7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

573413:SPIRS RS14270
gene id: 573413:SPIRS_RS14270
uniprot id: E1R243
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

573413:SPIRS RS13230
gene id: 573413:SPIRS_RS13230
uniprot id: E1R4I9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

573413:SPIRS RS18665
gene id: 573413:SPIRS_RS18665
uniprot id: E1R7T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

573413:SPIRS RS19610
gene id: 573413:SPIRS_RS19610
uniprot id: E1R907
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS15525
gene id: 573413:SPIRS_RS15525
uniprot id: E1R4T7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

573413:SPIRS RS06490
gene id: 573413:SPIRS_RS06490
uniprot id: E1R3Z4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

573413:SPIRS RS06900
gene id: 573413:SPIRS_RS06900
uniprot id: E1R471
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS08135
gene id: 573413:SPIRS_RS08135
uniprot id: E1R5X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS19700
gene id: 573413:SPIRS_RS19700
uniprot id: E1R925
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

573413:SPIRS RS11590
gene id: 573413:SPIRS_RS11590
uniprot id: E1R1N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

573413:SPIRS RS09740
gene id: 573413:SPIRS_RS09740
uniprot id: E1R1B0
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS04880
gene id: 573413:SPIRS_RS04880
uniprot id: E1RCL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

573413:SPIRS RS14410
gene id: 573413:SPIRS_RS14410
uniprot id: E1R271
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

573413:SPIRS RS17625
gene id: 573413:SPIRS_RS17625
uniprot id: E1R776
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

573413:SPIRS RS16335
gene id: 573413:SPIRS_RS16335
uniprot id: E1R5K5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

573413:SPIRS RS17560
gene id: 573413:SPIRS_RS17560
uniprot id: E1R2K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

573413:SPIRS RS00940
gene id: 573413:SPIRS_RS00940
uniprot id: E1R8J8
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

573413:SPIRS RS20230
gene id: 573413:SPIRS_RS20230
uniprot id: E1R9D0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

573413:SPIRS RS09285
gene id: 573413:SPIRS_RS09285
uniprot id: E1R6E2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

573413:SPIRS RS17915
gene id: 573413:SPIRS_RS17915
uniprot id: E1R7D4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

573413:SPIRS RS04725
gene id: 573413:SPIRS_RS04725
uniprot id: E1RCI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS03235
gene id: 573413:SPIRS_RS03235
uniprot id: E1RBQ0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

573413:SPIRS RS18075
gene id: 573413:SPIRS_RS18075
uniprot id: E1R7G5
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

573413:SPIRS RS02550
gene id: 573413:SPIRS_RS02550
uniprot id: E1RBC0
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS05385
gene id: 573413:SPIRS_RS05385
uniprot id: E1R0V3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

573413:SPIRS RS18985
gene id: 573413:SPIRS_RS18985
uniprot id: E1R7Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

573413:SPIRS RS16030
gene id: 573413:SPIRS_RS16030
uniprot id: E1R5E9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS13265
gene id: 573413:SPIRS_RS13265
uniprot id: E1R4J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

573413:SPIRS RS20730
gene id: 573413:SPIRS_RS20730
uniprot id: E1R9M9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS05720
gene id: 573413:SPIRS_RS05720
uniprot id: E1R117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

573413:SPIRS RS10365
gene id: 573413:SPIRS_RS10365
uniprot id: E1R2Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

573413:SPIRS RS02715
gene id: 573413:SPIRS_RS02715
uniprot id: E1RBF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

573413:SPIRS RS04875
gene id: 573413:SPIRS_RS04875
uniprot id: E1RCL7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

573413:SPIRS RS21145
gene id: 573413:SPIRS_RS21145
uniprot id: E1R9W0
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

573413:SPIRS RS13715
gene id: 573413:SPIRS_RS13715
uniprot id: E1R8R6
names: Similarity
messages: Belongs to the UPF0597 family.

573413:SPIRS RS05135
gene id: 573413:SPIRS_RS05135
uniprot id: E1RCS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

573413:SPIRS RS05255
gene id: 573413:SPIRS_RS05255
uniprot id: E1RCU5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

573413:SPIRS RS08250
gene id: 573413:SPIRS_RS08250
uniprot id: E1R5Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

573413:SPIRS RS00080
gene id: 573413:SPIRS_RS00080
uniprot id: E1R6P5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

573413:SPIRS RS11815
gene id: 573413:SPIRS_RS11815
uniprot id: E1R1T1
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS10655
gene id: 573413:SPIRS_RS10655
uniprot id: E1R342
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

573413:SPIRS RS20370
gene id: 573413:SPIRS_RS20370
uniprot id: E1R9F7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS04855
gene id: 573413:SPIRS_RS04855
uniprot id: E1RCL3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

573413:SPIRS RS19295
gene id: 573413:SPIRS_RS19295
uniprot id: E1R859
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

573413:SPIRS RS07995
gene id: 573413:SPIRS_RS07995
uniprot id: E1R5U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

573413:SPIRS RS07815
gene id: 573413:SPIRS_RS07815
uniprot id: E1R5Q6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

573413:SPIRS RS04995
gene id: 573413:SPIRS_RS04995
uniprot id: E1RCP3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

573413:SPIRS RS06980
gene id: 573413:SPIRS_RS06980
uniprot id: E1R487
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

573413:SPIRS RS07900
gene id: 573413:SPIRS_RS07900
uniprot id: E1R5S3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

573413:SPIRS RS13720
gene id: 573413:SPIRS_RS13720
uniprot id: E1R8R7
names: Similarity
messages: Belongs to the RutC family.

573413:SPIRS RS09495
gene id: 573413:SPIRS_RS09495
uniprot id: E1R6I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

573413:SPIRS RS00745
gene id: 573413:SPIRS_RS00745
uniprot id: E1R8G0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS01735
gene id: 573413:SPIRS_RS01735
uniprot id: E1RAW9
names: Similarity
messages: Belongs to the leucine-binding protein family.

573413:SPIRS RS16300
gene id: 573413:SPIRS_RS16300
uniprot id: E1R5J8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

573413:SPIRS RS17645
gene id: 573413:SPIRS_RS17645
uniprot id: E1R780
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS03805
gene id: 573413:SPIRS_RS03805
uniprot id: E1RC07
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS17960
gene id: 573413:SPIRS_RS17960
uniprot id: E1R7E3
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS03070
gene id: 573413:SPIRS_RS03070
uniprot id: E1RBM0
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

573413:SPIRS RS18025
gene id: 573413:SPIRS_RS18025
uniprot id: E1R7F5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

573413:SPIRS RS08840
gene id: 573413:SPIRS_RS08840
uniprot id: E1R155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS03580
gene id: 573413:SPIRS_RS03580
uniprot id: E1RBW2
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS10300
gene id: 573413:SPIRS_RS10300
uniprot id: E1R1L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

573413:SPIRS RS16375
gene id: 573413:SPIRS_RS16375
uniprot id: E1R5L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

573413:SPIRS RS20985
gene id: 573413:SPIRS_RS20985
uniprot id: E1R9T0
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS20425
gene id: 573413:SPIRS_RS20425
uniprot id: E1R9G8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

573413:SPIRS RS02300
gene id: 573413:SPIRS_RS02300
uniprot id: E1RB70
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

573413:SPIRS RS00300
gene id: 573413:SPIRS_RS00300
uniprot id: E1R6T9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

573413:SPIRS RS20615
gene id: 573413:SPIRS_RS20615
uniprot id: E1R9K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS18410
gene id: 573413:SPIRS_RS18410
uniprot id: E1R7N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS08835
gene id: 573413:SPIRS_RS08835
uniprot id: E1R154
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS17685
gene id: 573413:SPIRS_RS17685
uniprot id: E1R788
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

573413:SPIRS RS13640
gene id: 573413:SPIRS_RS13640
uniprot id: E1R8Q1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

573413:SPIRS RS21745
gene id: 573413:SPIRS_RS21745
uniprot id: E1R403
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

573413:SPIRS RS17075
gene id: 573413:SPIRS_RS17075
uniprot id: E1R2B5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

573413:SPIRS RS12215
gene id: 573413:SPIRS_RS12215
uniprot id: E1R3A1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

573413:SPIRS RS02690
gene id: 573413:SPIRS_RS02690
uniprot id: E1RBE6
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS11915
gene id: 573413:SPIRS_RS11915
uniprot id: E1R1V0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

573413:SPIRS RS14870
gene id: 573413:SPIRS_RS14870
uniprot id: E1R3S6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

573413:SPIRS RS19325
gene id: 573413:SPIRS_RS19325
uniprot id: E1R865
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

573413:SPIRS RS15695
gene id: 573413:SPIRS_RS15695
uniprot id: E1R4X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

573413:SPIRS RS14860
gene id: 573413:SPIRS_RS14860
uniprot id: E1R3S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

573413:SPIRS RS03850
gene id: 573413:SPIRS_RS03850
uniprot id: E1RC16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

573413:SPIRS RS01875
gene id: 573413:SPIRS_RS01875
uniprot id: E1RAZ7
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS05090
gene id: 573413:SPIRS_RS05090
uniprot id: E1RCR2
names: Similarity
messages: Belongs to the peptidase M29 family.

573413:SPIRS RS07835
gene id: 573413:SPIRS_RS07835
uniprot id: E1R5R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS04115
gene id: 573413:SPIRS_RS04115
uniprot id: E1RC70
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

573413:SPIRS RS16710
gene id: 573413:SPIRS_RS16710
uniprot id: E1RAN8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

573413:SPIRS RS10780
gene id: 573413:SPIRS_RS10780
uniprot id: E1R367
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

573413:SPIRS RS00720
gene id: 573413:SPIRS_RS00720
uniprot id: E1R8F5
names: Similarity
messages: Belongs to the PspA/IM30 family.

573413:SPIRS RS15020
gene id: 573413:SPIRS_RS15020
uniprot id: E1R3V5
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS01625
gene id: 573413:SPIRS_RS01625
uniprot id: E1RAU8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

573413:SPIRS RS16380
gene id: 573413:SPIRS_RS16380
uniprot id: E1R5L4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS12915
gene id: 573413:SPIRS_RS12915
uniprot id: E1R4C5
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS15580
gene id: 573413:SPIRS_RS15580
uniprot id: E1R4U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

573413:SPIRS RS11450
gene id: 573413:SPIRS_RS11450
uniprot id: E1R759
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

573413:SPIRS RS04070
gene id: 573413:SPIRS_RS04070
uniprot id: E1RC61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS07235
gene id: 573413:SPIRS_RS07235
uniprot id: E1R526
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

573413:SPIRS RS13850
gene id: 573413:SPIRS_RS13850
uniprot id: E1R8U1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

573413:SPIRS RS19960
gene id: 573413:SPIRS_RS19960
uniprot id: E1R977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

573413:SPIRS RS09140
gene id: 573413:SPIRS_RS09140
uniprot id: E1R6B4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

573413:SPIRS RS17780
gene id: 573413:SPIRS_RS17780
uniprot id: E1R7A7
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS00895
gene id: 573413:SPIRS_RS00895
uniprot id: E1R8J0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

573413:SPIRS RS16185
gene id: 573413:SPIRS_RS16185
uniprot id: E1R5I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

573413:SPIRS RS04320
gene id: 573413:SPIRS_RS04320
uniprot id: E1RCB1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

573413:SPIRS RS04750
gene id: 573413:SPIRS_RS04750
uniprot id: E1RCJ4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

573413:SPIRS RS01660
gene id: 573413:SPIRS_RS01660
uniprot id: E1RAV4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

573413:SPIRS RS08080
gene id: 573413:SPIRS_RS08080
uniprot id: E1R5V9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

573413:SPIRS RS20020
gene id: 573413:SPIRS_RS20020
uniprot id: E1R989
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

573413:SPIRS RS07150
gene id: 573413:SPIRS_RS07150
uniprot id: E1R508
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

573413:SPIRS RS02450
gene id: 573413:SPIRS_RS02450
uniprot id: E1RBA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

573413:SPIRS RS04055
gene id: 573413:SPIRS_RS04055
uniprot id: E1RC58
names: Similarity
messages: Belongs to the DapA family.

573413:SPIRS RS06460
gene id: 573413:SPIRS_RS06460
uniprot id: E1R2X9
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS15980
gene id: 573413:SPIRS_RS15980
uniprot id: E1R5D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

573413:SPIRS RS08305
gene id: 573413:SPIRS_RS08305
uniprot id: E1R605
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

573413:SPIRS RS07320
gene id: 573413:SPIRS_RS07320
uniprot id: E1R542
names: Similarity
messages: Belongs to the peptidase M18 family.

573413:SPIRS RS08350
gene id: 573413:SPIRS_RS08350
uniprot id: E1R614
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

573413:SPIRS RS17250
gene id: 573413:SPIRS_RS17250
uniprot id: E1R2E7
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS07175
gene id: 573413:SPIRS_RS07175
uniprot id: E1R513
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

573413:SPIRS RS08810
gene id: 573413:SPIRS_RS08810
uniprot id: E1R6A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

573413:SPIRS RS03750
gene id: 573413:SPIRS_RS03750
uniprot id: E1RBZ6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

573413:SPIRS RS08600
gene id: 573413:SPIRS_RS08600
uniprot id: E1R663
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

573413:SPIRS RS06220
gene id: 573413:SPIRS_RS06220
uniprot id: E1R2T1
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

573413:SPIRS RS07875
gene id: 573413:SPIRS_RS07875
uniprot id: E1R5R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

573413:SPIRS RS20875
gene id: 573413:SPIRS_RS20875
uniprot id: E1R9Q8
names: Subcellular Location Annotation
messages: Membrane

573413:SPIRS RS08150
gene id: 573413:SPIRS_RS08150
uniprot id: E1R5X4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS19485
gene id: 573413:SPIRS_RS19485
uniprot id: E1R8Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

573413:SPIRS RS11335
gene id: 573413:SPIRS_RS11335
uniprot id: E1R736
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

573413:SPIRS RS09750
gene id: 573413:SPIRS_RS09750
uniprot id: E1R1B2
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.