572544:ILYOP RS09340
gene id: 572544:ILYOP_RS09340
uniprot id: E3H9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

572544:ILYOP RS06390
gene id: 572544:ILYOP_RS06390
uniprot id: E3H9E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

572544:ILYOP RS02780
gene id: 572544:ILYOP_RS02780
uniprot id: E3H6B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

572544:ILYOP RS06015
gene id: 572544:ILYOP_RS06015
uniprot id: E3H8J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

572544:ILYOP RS00770
gene id: 572544:ILYOP_RS00770
uniprot id: E3H736
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

572544:ILYOP RS02410
gene id: 572544:ILYOP_RS02410
uniprot id: E3HB99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS08540
gene id: 572544:ILYOP_RS08540
uniprot id: E3HA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

572544:ILYOP RS04905
gene id: 572544:ILYOP_RS04905
uniprot id: E3H950
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

572544:ILYOP RS05430
gene id: 572544:ILYOP_RS05430
uniprot id: E3H7G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

572544:ILYOP RS12765
gene id: 572544:ILYOP_RS12765
uniprot id: E3HDS1
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS09755
gene id: 572544:ILYOP_RS09755
uniprot id: E3HAE9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

572544:ILYOP RS03875
gene id: 572544:ILYOP_RS03875
uniprot id: E3H764
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

572544:ILYOP RS08385
gene id: 572544:ILYOP_RS08385
uniprot id: E3H9Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

572544:ILYOP RS06970
gene id: 572544:ILYOP_RS06970
uniprot id: E3HA36
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

572544:ILYOP RS13915
gene id: 572544:ILYOP_RS13915
uniprot id: E3HCT8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

572544:ILYOP RS01140
gene id: 572544:ILYOP_RS01140
uniprot id: E3H8A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

572544:ILYOP RS00900
gene id: 572544:ILYOP_RS00900
uniprot id: E3H7K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

572544:ILYOP RS07885
gene id: 572544:ILYOP_RS07885
uniprot id: E3H8T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell inner membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

572544:ILYOP RS04060
gene id: 572544:ILYOP_RS04060
uniprot id: E3H7A0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

572544:ILYOP RS01860
gene id: 572544:ILYOP_RS01860
uniprot id: E3HAZ1
names: Subcellular Location Annotation
messages: Cytoplasm

572544:ILYOP RS03630
gene id: 572544:ILYOP_RS03630
uniprot id: E3H6X7
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS01845
gene id: 572544:ILYOP_RS01845
uniprot id: E3HAY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

572544:ILYOP RS12870
gene id: 572544:ILYOP_RS12870
uniprot id: E3HDU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

572544:ILYOP RS07320
gene id: 572544:ILYOP_RS07320
uniprot id: E3HAP7
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS14650
gene id: 572544:ILYOP_RS14650
uniprot id: E3HDZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

572544:ILYOP RS01920
gene id: 572544:ILYOP_RS01920
uniprot id: E3HB04
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

572544:ILYOP RS01945
gene id: 572544:ILYOP_RS01945
uniprot id: E3HB09
names: Similarity
messages: Belongs to the peptidase M16 family.

572544:ILYOP RS08990
gene id: 572544:ILYOP_RS08990
uniprot id: E3H901
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

572544:ILYOP RS04385
gene id: 572544:ILYOP_RS04385
uniprot id: E3H7R3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS06910
gene id: 572544:ILYOP_RS06910
uniprot id: E3HA24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

572544:ILYOP RS01385
gene id: 572544:ILYOP_RS01385
uniprot id: E3HAH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

572544:ILYOP RS05605
gene id: 572544:ILYOP_RS05605
uniprot id: E3H7U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

572544:ILYOP RS08750
gene id: 572544:ILYOP_RS08750
uniprot id: E3HAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

572544:ILYOP RS05860
gene id: 572544:ILYOP_RS05860
uniprot id: E3H7Z4
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

572544:ILYOP RS05970
gene id: 572544:ILYOP_RS05970
uniprot id: E3H8I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

572544:ILYOP RS12365
gene id: 572544:ILYOP_RS12365
uniprot id: E3HDJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

572544:ILYOP RS09360
gene id: 572544:ILYOP_RS09360
uniprot id: E3H9U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

572544:ILYOP RS02835
gene id: 572544:ILYOP_RS02835
uniprot id: E3H6C2
names: Similarity
messages: Belongs to the CitG/MdcB family.

572544:ILYOP RS12965
gene id: 572544:ILYOP_RS12965
uniprot id: E3HBX1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

572544:ILYOP RS09015
gene id: 572544:ILYOP_RS09015
uniprot id: E3H906
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

572544:ILYOP RS01930
gene id: 572544:ILYOP_RS01930
uniprot id: E3HB06
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS02225
gene id: 572544:ILYOP_RS02225
uniprot id: E3HB62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

572544:ILYOP RS00415
gene id: 572544:ILYOP_RS00415
uniprot id: E3H6A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

572544:ILYOP RS07325
gene id: 572544:ILYOP_RS07325
uniprot id: E3HAP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

572544:ILYOP RS04470
gene id: 572544:ILYOP_RS04470
uniprot id: E3H7S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

572544:ILYOP RS09790
gene id: 572544:ILYOP_RS09790
uniprot id: E3HBI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

572544:ILYOP RS02540
gene id: 572544:ILYOP_RS02540
uniprot id: E3H5Y6
names: Similarity
messages: Belongs to the MEMO1 family.

572544:ILYOP RS12855
gene id: 572544:ILYOP_RS12855
uniprot id: E3HDT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS08190
gene id: 572544:ILYOP_RS08190
uniprot id: E3H9L4
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

572544:ILYOP RS02740
gene id: 572544:ILYOP_RS02740
uniprot id: E3H626
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

572544:ILYOP RS09125
gene id: 572544:ILYOP_RS09125
uniprot id: E3H928
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

572544:ILYOP RS01025
gene id: 572544:ILYOP_RS01025
uniprot id: E3H881
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

572544:ILYOP RS02995
gene id: 572544:ILYOP_RS02995
uniprot id: E3H6F4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

572544:ILYOP RS12720
gene id: 572544:ILYOP_RS12720
uniprot id: E3HDR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

572544:ILYOP RS04095
gene id: 572544:ILYOP_RS04095
uniprot id: E3H7A7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS03580
gene id: 572544:ILYOP_RS03580
uniprot id: E3H6W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

572544:ILYOP RS07715
gene id: 572544:ILYOP_RS07715
uniprot id: E3H8P8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS14170
gene id: 572544:ILYOP_RS14170
uniprot id: E3HD54
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

572544:ILYOP RS13005
gene id: 572544:ILYOP_RS13005
uniprot id: E3HBX8
names: Similarity
messages: Belongs to the CvfB family.

572544:ILYOP RS00085
gene id: 572544:ILYOP_RS00085
uniprot id: E3H647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

572544:ILYOP RS08430
gene id: 572544:ILYOP_RS08430
uniprot id: E3HA44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

572544:ILYOP RS09685
gene id: 572544:ILYOP_RS09685
uniprot id: E3HAD5
names: Similarity
messages: Belongs to the peptidase M18 family.

572544:ILYOP RS02150
gene id: 572544:ILYOP_RS02150
uniprot id: E3HB47
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

572544:ILYOP RS12265
gene id: 572544:ILYOP_RS12265
uniprot id: E3HDH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

572544:ILYOP RS10740
gene id: 572544:ILYOP_RS10740
uniprot id: E3HC30
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

572544:ILYOP RS13285
gene id: 572544:ILYOP_RS13285
uniprot id: E3HC99
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS11855
gene id: 572544:ILYOP_RS11855
uniprot id: E3HD76
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

572544:ILYOP RS02535
gene id: 572544:ILYOP_RS02535
uniprot id: E3H5Y5
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

572544:ILYOP RS15020
gene id: 572544:ILYOP_RS15020
uniprot id: E3H666
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

572544:ILYOP RS07315
gene id: 572544:ILYOP_RS07315
uniprot id: E3HAP6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS12035
gene id: 572544:ILYOP_RS12035
uniprot id: E3HDB2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

572544:ILYOP RS01205
gene id: 572544:ILYOP_RS01205
uniprot id: E3H938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS12400
gene id: 572544:ILYOP_RS12400
uniprot id: E3HDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

572544:ILYOP RS12395
gene id: 572544:ILYOP_RS12395
uniprot id: E3HDJ7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

572544:ILYOP RS07330
gene id: 572544:ILYOP_RS07330
uniprot id: E3HAQ0
names: Function
names: Similarity
messages: Belongs to the type-2 OGG1 family.
messages: Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).

572544:ILYOP RS01130
gene id: 572544:ILYOP_RS01130
uniprot id: E3H899
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

572544:ILYOP RS09140
gene id: 572544:ILYOP_RS09140
uniprot id: E3H9Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

572544:ILYOP RS10205
gene id: 572544:ILYOP_RS10205
uniprot id: E3HBF9
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS07425
gene id: 572544:ILYOP_RS07425
uniprot id: E3H825
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

572544:ILYOP RS03800
gene id: 572544:ILYOP_RS03800
uniprot id: E3H711
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

572544:ILYOP RS09335
gene id: 572544:ILYOP_RS09335
uniprot id: E3H9U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

572544:ILYOP RS02160
gene id: 572544:ILYOP_RS02160
uniprot id: E3HB49
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

572544:ILYOP RS02170
gene id: 572544:ILYOP_RS02170
uniprot id: E3HB51
names: Similarity
messages: Belongs to the leucine-binding protein family.

572544:ILYOP RS15090
gene id: 572544:ILYOP_RS15090
uniprot id: E3H782
names: Similarity
messages: Belongs to the UPF0145 family.

572544:ILYOP RS01605
gene id: 572544:ILYOP_RS01605
uniprot id: E3HAT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

572544:ILYOP RS13165
gene id: 572544:ILYOP_RS13165
uniprot id: E3HC10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

572544:ILYOP RS14375
gene id: 572544:ILYOP_RS14375
uniprot id: E3HDF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS08380
gene id: 572544:ILYOP_RS08380
uniprot id: E3H9Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

572544:ILYOP RS06345
gene id: 572544:ILYOP_RS06345
uniprot id: E3H9D1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

572544:ILYOP RS04390
gene id: 572544:ILYOP_RS04390
uniprot id: E3H7R4
names: Similarity
messages: Belongs to the MipA/OmpV family.

572544:ILYOP RS03995
gene id: 572544:ILYOP_RS03995
uniprot id: E3H788
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS05885
gene id: 572544:ILYOP_RS05885
uniprot id: E3H7Z6
names: Similarity
messages: Belongs to the BMP lipoprotein family.

572544:ILYOP RS01910
gene id: 572544:ILYOP_RS01910
uniprot id: E3HB02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

572544:ILYOP RS14370
gene id: 572544:ILYOP_RS14370
uniprot id: E3HDF2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

572544:ILYOP RS12750
gene id: 572544:ILYOP_RS12750
uniprot id: E3HDR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

572544:ILYOP RS01940
gene id: 572544:ILYOP_RS01940
uniprot id: E3HB08
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS03520
gene id: 572544:ILYOP_RS03520
uniprot id: E3H6V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS05610
gene id: 572544:ILYOP_RS05610
uniprot id: E3H7U4
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

572544:ILYOP RS02265
gene id: 572544:ILYOP_RS02265
uniprot id: E3HB70
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS06625
gene id: 572544:ILYOP_RS06625
uniprot id: E3H9W9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

572544:ILYOP RS03910
gene id: 572544:ILYOP_RS03910
uniprot id: E3H771
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

572544:ILYOP RS09110
gene id: 572544:ILYOP_RS09110
uniprot id: E3H925
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

572544:ILYOP RS09330
gene id: 572544:ILYOP_RS09330
uniprot id: E3H9U0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

572544:ILYOP RS03475
gene id: 572544:ILYOP_RS03475
uniprot id: E3H6U5
names: Similarity
messages: Belongs to the UPF0735 family.

572544:ILYOP RS09070
gene id: 572544:ILYOP_RS09070
uniprot id: E3H917
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

572544:ILYOP RS11140
gene id: 572544:ILYOP_RS11140
uniprot id: E3HCG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

572544:ILYOP RS13775
gene id: 572544:ILYOP_RS13775
uniprot id: E3HCR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

572544:ILYOP RS02250
gene id: 572544:ILYOP_RS02250
uniprot id: E3HB67
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

572544:ILYOP RS02420
gene id: 572544:ILYOP_RS02420
uniprot id: E3HBA1
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS02130
gene id: 572544:ILYOP_RS02130
uniprot id: E3HB43
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

572544:ILYOP RS11730
gene id: 572544:ILYOP_RS11730
uniprot id: E3HCZ5
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS01065
gene id: 572544:ILYOP_RS01065
uniprot id: E3H887
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

572544:ILYOP RS13615
gene id: 572544:ILYOP_RS13615
uniprot id: E3HCM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

572544:ILYOP RS00040
gene id: 572544:ILYOP_RS00040
uniprot id: E3H638
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

572544:ILYOP RS03915
gene id: 572544:ILYOP_RS03915
uniprot id: E3H772
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS02020
gene id: 572544:ILYOP_RS02020
uniprot id: E3HB24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

572544:ILYOP RS13700
gene id: 572544:ILYOP_RS13700
uniprot id: E3HCP7
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS07255
gene id: 572544:ILYOP_RS07255
uniprot id: E3HAN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

572544:ILYOP RS02215
gene id: 572544:ILYOP_RS02215
uniprot id: E3HB60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

572544:ILYOP RS01710
gene id: 572544:ILYOP_RS01710
uniprot id: E3HAW0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

572544:ILYOP RS11910
gene id: 572544:ILYOP_RS11910
uniprot id: E3HD87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

572544:ILYOP RS07915
gene id: 572544:ILYOP_RS07915
uniprot id: E3H8T6
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

572544:ILYOP RS08435
gene id: 572544:ILYOP_RS08435
uniprot id: E3HA45
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

572544:ILYOP RS08945
gene id: 572544:ILYOP_RS08945
uniprot id: E3H8Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

572544:ILYOP RS13410
gene id: 572544:ILYOP_RS13410
uniprot id: E3HCC4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

572544:ILYOP RS02480
gene id: 572544:ILYOP_RS02480
uniprot id: E3HBB3
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

572544:ILYOP RS00980
gene id: 572544:ILYOP_RS00980
uniprot id: E3H7L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

572544:ILYOP RS12995
gene id: 572544:ILYOP_RS12995
uniprot id: E3HBX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

572544:ILYOP RS07790
gene id: 572544:ILYOP_RS07790
uniprot id: E3H8R1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

572544:ILYOP RS02600
gene id: 572544:ILYOP_RS02600
uniprot id: E3H5Z8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS04645
gene id: 572544:ILYOP_RS04645
uniprot id: E3H8C7
names: Similarity
messages: Belongs to the peptidase U62 family.

572544:ILYOP RS09075
gene id: 572544:ILYOP_RS09075
uniprot id: E3H918
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

572544:ILYOP RS13805
gene id: 572544:ILYOP_RS13805
uniprot id: E3HCR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

572544:ILYOP RS03365
gene id: 572544:ILYOP_RS03365
uniprot id: E3H6S3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS03185
gene id: 572544:ILYOP_RS03185
uniprot id: E3H6N7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS12005
gene id: 572544:ILYOP_RS12005
uniprot id: E3HDA6
names: Subcellular Location Annotation
messages: Bacterial microcompartment

572544:ILYOP RS07600
gene id: 572544:ILYOP_RS07600
uniprot id: E3H859
names: Similarity
messages: Belongs to the fabD family.

572544:ILYOP RS13975
gene id: 572544:ILYOP_RS13975
uniprot id: E3HD19
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

572544:ILYOP RS12375
gene id: 572544:ILYOP_RS12375
uniprot id: E3HDJ3
names: Similarity
messages: Belongs to the peptidase M16 family.

572544:ILYOP RS07740
gene id: 572544:ILYOP_RS07740
uniprot id: E3H8Q3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

572544:ILYOP RS06810
gene id: 572544:ILYOP_RS06810
uniprot id: E3HA04
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

572544:ILYOP RS13230
gene id: 572544:ILYOP_RS13230
uniprot id: E3HC21
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS06470
gene id: 572544:ILYOP_RS06470
uniprot id: E3H9F6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

572544:ILYOP RS07830
gene id: 572544:ILYOP_RS07830
uniprot id: E3H8R9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

572544:ILYOP RS07135
gene id: 572544:ILYOP_RS07135
uniprot id: E3HAL0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

572544:ILYOP RS13575
gene id: 572544:ILYOP_RS13575
uniprot id: E3HCF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

572544:ILYOP RS06675
gene id: 572544:ILYOP_RS06675
uniprot id: E3H9X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

572544:ILYOP RS03765
gene id: 572544:ILYOP_RS03765
uniprot id: E3H704
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

572544:ILYOP RS12315
gene id: 572544:ILYOP_RS12315
uniprot id: E3HDI1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

572544:ILYOP RS15235
gene id: 572544:ILYOP_RS15235
uniprot id: E3HBM4
names: Similarity
messages: Belongs to the peptidase S14 family.

572544:ILYOP RS09375
gene id: 572544:ILYOP_RS09375
uniprot id: E3H9U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

572544:ILYOP RS09020
gene id: 572544:ILYOP_RS09020
uniprot id: E3H907
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

572544:ILYOP RS10965
gene id: 572544:ILYOP_RS10965
uniprot id: E3HC74
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

572544:ILYOP RS11005
gene id: 572544:ILYOP_RS11005
uniprot id: E3HC82
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

572544:ILYOP RS03275
gene id: 572544:ILYOP_RS03275
uniprot id: E3H6Q4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

572544:ILYOP RS01060
gene id: 572544:ILYOP_RS01060
uniprot id: E3H885
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

572544:ILYOP RS03005
gene id: 572544:ILYOP_RS03005
uniprot id: E3H6F6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

572544:ILYOP RS03495
gene id: 572544:ILYOP_RS03495
uniprot id: E3H6U9
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS06490
gene id: 572544:ILYOP_RS06490
uniprot id: E3H9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

572544:ILYOP RS01950
gene id: 572544:ILYOP_RS01950
uniprot id: E3HB10
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

572544:ILYOP RS12500
gene id: 572544:ILYOP_RS12500
uniprot id: E3HDL7
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS06385
gene id: 572544:ILYOP_RS06385
uniprot id: E3H9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

572544:ILYOP RS14135
gene id: 572544:ILYOP_RS14135
uniprot id: E3HD47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

572544:ILYOP RS01190
gene id: 572544:ILYOP_RS01190
uniprot id: E3H935
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

572544:ILYOP RS04105
gene id: 572544:ILYOP_RS04105
uniprot id: E3H7A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

572544:ILYOP RS12180
gene id: 572544:ILYOP_RS12180
uniprot id: E3HDE1
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

572544:ILYOP RS10255
gene id: 572544:ILYOP_RS10255
uniprot id: E3HBG5
names: Similarity
messages: Belongs to the asparagine synthetase family.

572544:ILYOP RS00665
gene id: 572544:ILYOP_RS00665
uniprot id: E3H6M6
names: Similarity
messages: Belongs to the RutC family.

572544:ILYOP RS07695
gene id: 572544:ILYOP_RS07695
uniprot id: E3H8P5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

572544:ILYOP RS01585
gene id: 572544:ILYOP_RS01585
uniprot id: E3HAT5
names: Subcellular Location Annotation
messages: Cytoplasm

572544:ILYOP RS06325
gene id: 572544:ILYOP_RS06325
uniprot id: E3H9C7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS02655
gene id: 572544:ILYOP_RS02655
uniprot id: E3H609
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

572544:ILYOP RS06555
gene id: 572544:ILYOP_RS06555
uniprot id: E3H9H4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

572544:ILYOP RS07535
gene id: 572544:ILYOP_RS07535
uniprot id: E3H845
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

572544:ILYOP RS07590
gene id: 572544:ILYOP_RS07590
uniprot id: E3H857
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

572544:ILYOP RS01490
gene id: 572544:ILYOP_RS01490
uniprot id: E3HAR6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

572544:ILYOP RS15140
gene id: 572544:ILYOP_RS15140
uniprot id: E3H7C6
names: Similarity
messages: Belongs to the peptidase S14 family.

572544:ILYOP RS08270
gene id: 572544:ILYOP_RS08270
uniprot id: E3H9M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS04290
gene id: 572544:ILYOP_RS04290
uniprot id: E3H7P5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

572544:ILYOP RS12310
gene id: 572544:ILYOP_RS12310
uniprot id: E3HDI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

572544:ILYOP RS00255
gene id: 572544:ILYOP_RS00255
uniprot id: E3H673
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

572544:ILYOP RS08605
gene id: 572544:ILYOP_RS08605
uniprot id: E3HA79
names: Similarity
messages: Belongs to the peptidase S41A family.

572544:ILYOP RS07360
gene id: 572544:ILYOP_RS07360
uniprot id: E3H812
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

572544:ILYOP RS03340
gene id: 572544:ILYOP_RS03340
uniprot id: E3H6R8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

572544:ILYOP RS10730
gene id: 572544:ILYOP_RS10730
uniprot id: E3HBV9
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS11680
gene id: 572544:ILYOP_RS11680
uniprot id: E3HCY5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

572544:ILYOP RS07945
gene id: 572544:ILYOP_RS07945
uniprot id: E3H8U2
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN covalently per subunit.

572544:ILYOP RS07850
gene id: 572544:ILYOP_RS07850
uniprot id: E3H8S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS14240
gene id: 572544:ILYOP_RS14240
uniprot id: E3HD59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

572544:ILYOP RS14475
gene id: 572544:ILYOP_RS14475
uniprot id: E3HDW4
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

572544:ILYOP RS00670
gene id: 572544:ILYOP_RS00670
uniprot id: E3H716
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

572544:ILYOP RS09080
gene id: 572544:ILYOP_RS09080
uniprot id: E3H919
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

572544:ILYOP RS07795
gene id: 572544:ILYOP_RS07795
uniprot id: E3H8R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS06145
gene id: 572544:ILYOP_RS06145
uniprot id: E3H8L9
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Belongs to the complex I 51 kDa subunit family.

572544:ILYOP RS10750
gene id: 572544:ILYOP_RS10750
uniprot id: E3HC31
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

572544:ILYOP RS08460
gene id: 572544:ILYOP_RS08460
uniprot id: E3HA50
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS05770
gene id: 572544:ILYOP_RS05770
uniprot id: E3H7X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

572544:ILYOP RS10790
gene id: 572544:ILYOP_RS10790
uniprot id: E3HC39
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

572544:ILYOP RS06955
gene id: 572544:ILYOP_RS06955
uniprot id: E3HA33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

572544:ILYOP RS07395
gene id: 572544:ILYOP_RS07395
uniprot id: E3H819
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

572544:ILYOP RS01395
gene id: 572544:ILYOP_RS01395
uniprot id: E3HAH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

572544:ILYOP RS01905
gene id: 572544:ILYOP_RS01905
uniprot id: E3HB01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

572544:ILYOP RS07085
gene id: 572544:ILYOP_RS07085
uniprot id: E3HAK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

572544:ILYOP RS12140
gene id: 572544:ILYOP_RS12140
uniprot id: E3HDD3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

572544:ILYOP RS07350
gene id: 572544:ILYOP_RS07350
uniprot id: E3H810
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

572544:ILYOP RS07780
gene id: 572544:ILYOP_RS07780
uniprot id: E3H8Q9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS13520
gene id: 572544:ILYOP_RS13520
uniprot id: E3HCE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS06360
gene id: 572544:ILYOP_RS06360
uniprot id: E3H9D4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

572544:ILYOP RS07160
gene id: 572544:ILYOP_RS07160
uniprot id: E3HAL5
names: Similarity
messages: Belongs to the IMPACT family.

572544:ILYOP RS02625
gene id: 572544:ILYOP_RS02625
uniprot id: E3H603
names: Similarity
messages: Belongs to the Nudix hydrolase family.

572544:ILYOP RS02855
gene id: 572544:ILYOP_RS02855
uniprot id: E3H6C6
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS10725
gene id: 572544:ILYOP_RS10725
uniprot id: E3HBV8
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS05760
gene id: 572544:ILYOP_RS05760
uniprot id: E3H7X4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

572544:ILYOP RS03025
gene id: 572544:ILYOP_RS03025
uniprot id: E3H6G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

572544:ILYOP RS08865
gene id: 572544:ILYOP_RS08865
uniprot id: E3H8X6
names: Similarity
messages: Belongs to the pyruvate kinase family.

572544:ILYOP RS12845
gene id: 572544:ILYOP_RS12845
uniprot id: E3HDT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS12405
gene id: 572544:ILYOP_RS12405
uniprot id: E3HDJ9
names: Similarity
messages: Belongs to the aspartokinase family.

572544:ILYOP RS12320
gene id: 572544:ILYOP_RS12320
uniprot id: E3HDI2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

572544:ILYOP RS00175
gene id: 572544:ILYOP_RS00175
uniprot id: E3H665
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

572544:ILYOP RS02175
gene id: 572544:ILYOP_RS02175
uniprot id: E3HB52
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS12090
gene id: 572544:ILYOP_RS12090
uniprot id: E3HDC3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

572544:ILYOP RS12175
gene id: 572544:ILYOP_RS12175
uniprot id: E3HDE0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS07355
gene id: 572544:ILYOP_RS07355
uniprot id: E3H811
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

572544:ILYOP RS13335
gene id: 572544:ILYOP_RS13335
uniprot id: E3HCA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

572544:ILYOP RS03835
gene id: 572544:ILYOP_RS03835
uniprot id: E3H756
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

572544:ILYOP RS10775
gene id: 572544:ILYOP_RS10775
uniprot id: E3HC36
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

572544:ILYOP RS06830
gene id: 572544:ILYOP_RS06830
uniprot id: E3HA08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

572544:ILYOP RS00290
gene id: 572544:ILYOP_RS00290
uniprot id: E3H680
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

572544:ILYOP RS04460
gene id: 572544:ILYOP_RS04460
uniprot id: E3H7S7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

572544:ILYOP RS09470
gene id: 572544:ILYOP_RS09470
uniprot id: E3H9V6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

572544:ILYOP RS10355
gene id: 572544:ILYOP_RS10355
uniprot id: E3HBI3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

572544:ILYOP RS07630
gene id: 572544:ILYOP_RS07630
uniprot id: E3H865
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

572544:ILYOP RS12220
gene id: 572544:ILYOP_RS12220
uniprot id: E3HDG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS10910
gene id: 572544:ILYOP_RS10910
uniprot id: E3HC63
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

572544:ILYOP RS05715
gene id: 572544:ILYOP_RS05715
uniprot id: E3H7W5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

572544:ILYOP RS07775
gene id: 572544:ILYOP_RS07775
uniprot id: E3H8Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

572544:ILYOP RS07560
gene id: 572544:ILYOP_RS07560
uniprot id: E3H851
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

572544:ILYOP RS14140
gene id: 572544:ILYOP_RS14140
uniprot id: E3HD48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

572544:ILYOP RS00120
gene id: 572544:ILYOP_RS00120
uniprot id: E3H654
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

572544:ILYOP RS04410
gene id: 572544:ILYOP_RS04410
uniprot id: E3H7R7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

572544:ILYOP RS01650
gene id: 572544:ILYOP_RS01650
uniprot id: E3HAU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

572544:ILYOP RS06475
gene id: 572544:ILYOP_RS06475
uniprot id: E3H9F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

572544:ILYOP RS03165
gene id: 572544:ILYOP_RS03165
uniprot id: E3H6N3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

572544:ILYOP RS09775
gene id: 572544:ILYOP_RS09775
uniprot id: E3HBI6
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS06660
gene id: 572544:ILYOP_RS06660
uniprot id: E3H9X6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

572544:ILYOP RS09350
gene id: 572544:ILYOP_RS09350
uniprot id: E3H9U4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

572544:ILYOP RS09325
gene id: 572544:ILYOP_RS09325
uniprot id: E3H9T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

572544:ILYOP RS00055
gene id: 572544:ILYOP_RS00055
uniprot id: E3H641
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

572544:ILYOP RS12355
gene id: 572544:ILYOP_RS12355
uniprot id: E3HDI9
names: Similarity
messages: Belongs to the TrpF family.

572544:ILYOP RS01655
gene id: 572544:ILYOP_RS01655
uniprot id: E3HAU9
names: Similarity
messages: Belongs to the UPF0751 family.

572544:ILYOP RS00245
gene id: 572544:ILYOP_RS00245
uniprot id: E3H671
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

572544:ILYOP RS08525
gene id: 572544:ILYOP_RS08525
uniprot id: E3HA63
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

572544:ILYOP RS02975
gene id: 572544:ILYOP_RS02975
uniprot id: E3H6F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

572544:ILYOP RS05460
gene id: 572544:ILYOP_RS05460
uniprot id: E3H7G9
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

572544:ILYOP RS11295
gene id: 572544:ILYOP_RS11295
uniprot id: E3HCJ4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

572544:ILYOP RS10805
gene id: 572544:ILYOP_RS10805
uniprot id: E3HC42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

572544:ILYOP RS12360
gene id: 572544:ILYOP_RS12360
uniprot id: E3HDJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

572544:ILYOP RS06320
gene id: 572544:ILYOP_RS06320
uniprot id: E3H9C6
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

572544:ILYOP RS14355
gene id: 572544:ILYOP_RS14355
uniprot id: E3HDE9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

572544:ILYOP RS06690
gene id: 572544:ILYOP_RS06690
uniprot id: E3H9Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

572544:ILYOP RS08700
gene id: 572544:ILYOP_RS08700
uniprot id: E3HA98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

572544:ILYOP RS08520
gene id: 572544:ILYOP_RS08520
uniprot id: E3HA62
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

572544:ILYOP RS06645
gene id: 572544:ILYOP_RS06645
uniprot id: E3H9X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

572544:ILYOP RS00965
gene id: 572544:ILYOP_RS00965
uniprot id: E3H7L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

572544:ILYOP RS14965
gene id: 572544:ILYOP_RS14965
uniprot id: E3HE49
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

572544:ILYOP RS02865
gene id: 572544:ILYOP_RS02865
uniprot id: E3H6C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

572544:ILYOP RS15060
gene id: 572544:ILYOP_RS15060
uniprot id: E3H5Z2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

572544:ILYOP RS09010
gene id: 572544:ILYOP_RS09010
uniprot id: E3H905
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

572544:ILYOP RS12700
gene id: 572544:ILYOP_RS12700
uniprot id: E3HDQ7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

572544:ILYOP RS08650
gene id: 572544:ILYOP_RS08650
uniprot id: E3HA88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

572544:ILYOP RS09170
gene id: 572544:ILYOP_RS09170
uniprot id: E3H9R2
names: Similarity
messages: Belongs to the bacterial secretin family.

572544:ILYOP RS06120
gene id: 572544:ILYOP_RS06120
uniprot id: E3H8L3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

572544:ILYOP RS07025
gene id: 572544:ILYOP_RS07025
uniprot id: E3HAI8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

572544:ILYOP RS09100
gene id: 572544:ILYOP_RS09100
uniprot id: E3H923
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

572544:ILYOP RS13720
gene id: 572544:ILYOP_RS13720
uniprot id: E3HCQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

572544:ILYOP RS01775
gene id: 572544:ILYOP_RS01775
uniprot id: E3HAX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS02575
gene id: 572544:ILYOP_RS02575
uniprot id: E3H5Z3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

572544:ILYOP RS10765
gene id: 572544:ILYOP_RS10765
uniprot id: E3HC34
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

572544:ILYOP RS00810
gene id: 572544:ILYOP_RS00810
uniprot id: E3H744
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

572544:ILYOP RS03395
gene id: 572544:ILYOP_RS03395
uniprot id: E3H6S9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

572544:ILYOP RS09650
gene id: 572544:ILYOP_RS09650
uniprot id: E3HAD1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

572544:ILYOP RS05555
gene id: 572544:ILYOP_RS05555
uniprot id: E3H7I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

572544:ILYOP RS06990
gene id: 572544:ILYOP_RS06990
uniprot id: E3HAI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

572544:ILYOP RS07080
gene id: 572544:ILYOP_RS07080
uniprot id: E3HAJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

572544:ILYOP RS01340
gene id: 572544:ILYOP_RS01340
uniprot id: E3HAG3
names: Similarity
messages: Belongs to the GSP E family.

572544:ILYOP RS02895
gene id: 572544:ILYOP_RS02895
uniprot id: E3H6D4
names: Subcellular Location Annotation
messages: Cytoplasm

572544:ILYOP RS02990
gene id: 572544:ILYOP_RS02990
uniprot id: E3H6F3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

572544:ILYOP RS03415
gene id: 572544:ILYOP_RS03415
uniprot id: E3H6T3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS10595
gene id: 572544:ILYOP_RS10595
uniprot id: E3HBT2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

572544:ILYOP RS12850
gene id: 572544:ILYOP_RS12850
uniprot id: E3HDT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

572544:ILYOP RS08955
gene id: 572544:ILYOP_RS08955
uniprot id: E3H8Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

572544:ILYOP RS06155
gene id: 572544:ILYOP_RS06155
uniprot id: E3H8M1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

572544:ILYOP RS01165
gene id: 572544:ILYOP_RS01165
uniprot id: E3H930
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

572544:ILYOP RS10345
gene id: 572544:ILYOP_RS10345
uniprot id: E3HBI1
names: Similarity
messages: Belongs to the class-I fumarase family.

572544:ILYOP RS06570
gene id: 572544:ILYOP_RS06570
uniprot id: E3H9H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

572544:ILYOP RS08720
gene id: 572544:ILYOP_RS08720
uniprot id: E3HAA2
names: Subcellular Location Annotation
messages: Cytoplasm

572544:ILYOP RS09730
gene id: 572544:ILYOP_RS09730
uniprot id: E3HAE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

572544:ILYOP RS10715
gene id: 572544:ILYOP_RS10715
uniprot id: E3HBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

572544:ILYOP RS12530
gene id: 572544:ILYOP_RS12530
uniprot id: E3HDM3
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS06705
gene id: 572544:ILYOP_RS06705
uniprot id: E3H9Y3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

572544:ILYOP RS08975
gene id: 572544:ILYOP_RS08975
uniprot id: E3H8Z8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

572544:ILYOP RS12390
gene id: 572544:ILYOP_RS12390
uniprot id: E3HDJ6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

572544:ILYOP RS03400
gene id: 572544:ILYOP_RS03400
uniprot id: E3H6T0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

572544:ILYOP RS13885
gene id: 572544:ILYOP_RS13885
uniprot id: E3HCT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS04275
gene id: 572544:ILYOP_RS04275
uniprot id: E3H7P2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

572544:ILYOP RS10185
gene id: 572544:ILYOP_RS10185
uniprot id: E3HBF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

572544:ILYOP RS05855
gene id: 572544:ILYOP_RS05855
uniprot id: E3H7Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

572544:ILYOP RS13345
gene id: 572544:ILYOP_RS13345
uniprot id: E3HCB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

572544:ILYOP RS11560
gene id: 572544:ILYOP_RS11560
uniprot id: E3HCW4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

572544:ILYOP RS14815
gene id: 572544:ILYOP_RS14815
uniprot id: E3HE24
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

572544:ILYOP RS06200
gene id: 572544:ILYOP_RS06200
uniprot id: E3H8N0
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

572544:ILYOP RS12630
gene id: 572544:ILYOP_RS12630
uniprot id: E3HDP2
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS02325
gene id: 572544:ILYOP_RS02325
uniprot id: E3HB82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

572544:ILYOP RS02195
gene id: 572544:ILYOP_RS02195
uniprot id: E3HB56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

572544:ILYOP RS15655
gene id: 572544:ILYOP_RS15655
uniprot id: E3HCI7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

572544:ILYOP RS04745
gene id: 572544:ILYOP_RS04745
uniprot id: E3H8E9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

572544:ILYOP RS08195
gene id: 572544:ILYOP_RS08195
uniprot id: E3H9L5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

572544:ILYOP RS12710
gene id: 572544:ILYOP_RS12710
uniprot id: E3HDQ9
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

572544:ILYOP RS02110
gene id: 572544:ILYOP_RS02110
uniprot id: E3HB41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

572544:ILYOP RS10770
gene id: 572544:ILYOP_RS10770
uniprot id: E3HC35
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

572544:ILYOP RS03460
gene id: 572544:ILYOP_RS03460
uniprot id: E3H6U2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

572544:ILYOP RS03465
gene id: 572544:ILYOP_RS03465
uniprot id: E3H6U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

572544:ILYOP RS12820
gene id: 572544:ILYOP_RS12820
uniprot id: E3HDT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS05780
gene id: 572544:ILYOP_RS05780
uniprot id: E3H7X8
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

572544:ILYOP RS13220
gene id: 572544:ILYOP_RS13220
uniprot id: E3HC19
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

572544:ILYOP RS14720
gene id: 572544:ILYOP_RS14720
uniprot id: E3HE05
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

572544:ILYOP RS00895
gene id: 572544:ILYOP_RS00895
uniprot id: E3H7K3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

572544:ILYOP RS07750
gene id: 572544:ILYOP_RS07750
uniprot id: E3H8Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

572544:ILYOP RS09145
gene id: 572544:ILYOP_RS09145
uniprot id: E3H9Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

572544:ILYOP RS03000
gene id: 572544:ILYOP_RS03000
uniprot id: E3H6F5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

572544:ILYOP RS13935
gene id: 572544:ILYOP_RS13935
uniprot id: E3HCU2
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

572544:ILYOP RS05680
gene id: 572544:ILYOP_RS05680
uniprot id: E3H7V8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

572544:ILYOP RS06315
gene id: 572544:ILYOP_RS06315
uniprot id: E3H9C5
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

572544:ILYOP RS06870
gene id: 572544:ILYOP_RS06870
uniprot id: E3HA16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

572544:ILYOP RS07975
gene id: 572544:ILYOP_RS07975
uniprot id: E3H8U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS10800
gene id: 572544:ILYOP_RS10800
uniprot id: E3HC41
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS10955
gene id: 572544:ILYOP_RS10955
uniprot id: E3HC72
names: Similarity
messages: Belongs to the nitroreductase family.

572544:ILYOP RS04195
gene id: 572544:ILYOP_RS04195
uniprot id: E3H7M6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

572544:ILYOP RS05475
gene id: 572544:ILYOP_RS05475
uniprot id: E3H7H2
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

572544:ILYOP RS05840
gene id: 572544:ILYOP_RS05840
uniprot id: E3H7Z0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS03780
gene id: 572544:ILYOP_RS03780
uniprot id: E3H707
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

572544:ILYOP RS01450
gene id: 572544:ILYOP_RS01450
uniprot id: E3HAQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

572544:ILYOP RS11020
gene id: 572544:ILYOP_RS11020
uniprot id: E3HC86
names: Similarity
messages: Belongs to the peptidase M18 family.

572544:ILYOP RS09315
gene id: 572544:ILYOP_RS09315
uniprot id: E3H9T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

572544:ILYOP RS06760
gene id: 572544:ILYOP_RS06760
uniprot id: E3H9Z4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

572544:ILYOP RS05665
gene id: 572544:ILYOP_RS05665
uniprot id: E3H7V5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

572544:ILYOP RS00110
gene id: 572544:ILYOP_RS00110
uniprot id: E3H652
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

572544:ILYOP RS08470
gene id: 572544:ILYOP_RS08470
uniprot id: E3HA52
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

572544:ILYOP RS04950
gene id: 572544:ILYOP_RS04950
uniprot id: E3H959
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS09815
gene id: 572544:ILYOP_RS09815
uniprot id: E3HBJ4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

572544:ILYOP RS05600
gene id: 572544:ILYOP_RS05600
uniprot id: E3H7U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

572544:ILYOP RS12770
gene id: 572544:ILYOP_RS12770
uniprot id: E3HDS2
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

572544:ILYOP RS01900
gene id: 572544:ILYOP_RS01900
uniprot id: E3HB00
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

572544:ILYOP RS07665
gene id: 572544:ILYOP_RS07665
uniprot id: E3H872
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

572544:ILYOP RS00910
gene id: 572544:ILYOP_RS00910
uniprot id: E3H7K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

572544:ILYOP RS03195
gene id: 572544:ILYOP_RS03195
uniprot id: E3H6N9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

572544:ILYOP RS12615
gene id: 572544:ILYOP_RS12615
uniprot id: E3HDN9
names: Similarity
messages: Belongs to the thioredoxin family.

572544:ILYOP RS11650
gene id: 572544:ILYOP_RS11650
uniprot id: E3HCX9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

572544:ILYOP RS12740
gene id: 572544:ILYOP_RS12740
uniprot id: E3HDR6
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

572544:ILYOP RS03355
gene id: 572544:ILYOP_RS03355
uniprot id: E3H6S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

572544:ILYOP RS04220
gene id: 572544:ILYOP_RS04220
uniprot id: E3H7N1
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

572544:ILYOP RS11600
gene id: 572544:ILYOP_RS11600
uniprot id: E3HCX0
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

572544:ILYOP RS04080
gene id: 572544:ILYOP_RS04080
uniprot id: E3H7A4
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS12440
gene id: 572544:ILYOP_RS12440
uniprot id: E3HDK5
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS00985
gene id: 572544:ILYOP_RS00985
uniprot id: E3H7L5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

572544:ILYOP RS14380
gene id: 572544:ILYOP_RS14380
uniprot id: E3HDF4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

572544:ILYOP RS12745
gene id: 572544:ILYOP_RS12745
uniprot id: E3HDR7
names: Caution
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

572544:ILYOP RS06180
gene id: 572544:ILYOP_RS06180
uniprot id: E3H8M6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

572544:ILYOP RS05560
gene id: 572544:ILYOP_RS05560
uniprot id: E3H7J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

572544:ILYOP RS08950
gene id: 572544:ILYOP_RS08950
uniprot id: E3H8Z3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS13255
gene id: 572544:ILYOP_RS13255
uniprot id: E3HC26
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

572544:ILYOP RS06735
gene id: 572544:ILYOP_RS06735
uniprot id: E3H9Y9
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

572544:ILYOP RS02260
gene id: 572544:ILYOP_RS02260
uniprot id: E3HB69
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS00305
gene id: 572544:ILYOP_RS00305
uniprot id: E3H683
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

572544:ILYOP RS12930
gene id: 572544:ILYOP_RS12930
uniprot id: E3HBW4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

572544:ILYOP RS00330
gene id: 572544:ILYOP_RS00330
uniprot id: E3H688
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

572544:ILYOP RS06965
gene id: 572544:ILYOP_RS06965
uniprot id: E3HA35
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

572544:ILYOP RS03455
gene id: 572544:ILYOP_RS03455
uniprot id: E3H6U1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

572544:ILYOP RS01360
gene id: 572544:ILYOP_RS01360
uniprot id: E3HAG7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

572544:ILYOP RS10670
gene id: 572544:ILYOP_RS10670
uniprot id: E3HBU7
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

572544:ILYOP RS00270
gene id: 572544:ILYOP_RS00270
uniprot id: E3H676
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

572544:ILYOP RS00115
gene id: 572544:ILYOP_RS00115
uniprot id: E3H653
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

572544:ILYOP RS10130
gene id: 572544:ILYOP_RS10130
uniprot id: E3HBE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

572544:ILYOP RS03020
gene id: 572544:ILYOP_RS03020
uniprot id: E3H6F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

572544:ILYOP RS00035
gene id: 572544:ILYOP_RS00035
uniprot id: E3H637
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

572544:ILYOP RS01180
gene id: 572544:ILYOP_RS01180
uniprot id: E3H933
names: Similarity
messages: Belongs to the CinA family.

572544:ILYOP RS08425
gene id: 572544:ILYOP_RS08425
uniprot id: E3HA43
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

572544:ILYOP RS00280
gene id: 572544:ILYOP_RS00280
uniprot id: E3H678
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS13780
gene id: 572544:ILYOP_RS13780
uniprot id: E3HCR1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

572544:ILYOP RS13235
gene id: 572544:ILYOP_RS13235
uniprot id: E3HC22
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

572544:ILYOP RS06425
gene id: 572544:ILYOP_RS06425
uniprot id: E3H9E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

572544:ILYOP RS07990
gene id: 572544:ILYOP_RS07990
uniprot id: E3H8V0
names: Similarity
messages: Belongs to the UPF0251 family.

572544:ILYOP RS06885
gene id: 572544:ILYOP_RS06885
uniprot id: E3HA19
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

572544:ILYOP RS06665
gene id: 572544:ILYOP_RS06665
uniprot id: E3H9X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

572544:ILYOP RS08500
gene id: 572544:ILYOP_RS08500
uniprot id: E3HA58
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

572544:ILYOP RS02695
gene id: 572544:ILYOP_RS02695
uniprot id: E3H617
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS01995
gene id: 572544:ILYOP_RS01995
uniprot id: E3HB19
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

572544:ILYOP RS08985
gene id: 572544:ILYOP_RS08985
uniprot id: E3H900
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

572544:ILYOP RS01070
gene id: 572544:ILYOP_RS01070
uniprot id: E3H888
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

572544:ILYOP RS03080
gene id: 572544:ILYOP_RS03080
uniprot id: E3H6H2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

572544:ILYOP RS11520
gene id: 572544:ILYOP_RS11520
uniprot id: E3HCV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

572544:ILYOP RS06900
gene id: 572544:ILYOP_RS06900
uniprot id: E3HA22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

572544:ILYOP RS07245
gene id: 572544:ILYOP_RS07245
uniprot id: E3HAN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

572544:ILYOP RS13755
gene id: 572544:ILYOP_RS13755
uniprot id: E3HCQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Membrane

572544:ILYOP RS01575
gene id: 572544:ILYOP_RS01575
uniprot id: E3HAT3
names: Subcellular Location Annotation
messages: Cytoplasm

572544:ILYOP RS15170
gene id: 572544:ILYOP_RS15170
uniprot id: E3HAL8
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS09210
gene id: 572544:ILYOP_RS09210
uniprot id: E3H9S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

572544:ILYOP RS02510
gene id: 572544:ILYOP_RS02510
uniprot id: E3H5Y0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

572544:ILYOP RS05955
gene id: 572544:ILYOP_RS05955
uniprot id: E3H8I0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

572544:ILYOP RS13000
gene id: 572544:ILYOP_RS13000
uniprot id: E3HBX7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

572544:ILYOP RS07235
gene id: 572544:ILYOP_RS07235
uniprot id: E3HAN0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

572544:ILYOP RS13150
gene id: 572544:ILYOP_RS13150
uniprot id: E3HC07
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

572544:ILYOP RS11990
gene id: 572544:ILYOP_RS11990
uniprot id: E3HDA3
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

572544:ILYOP RS08705
gene id: 572544:ILYOP_RS08705
uniprot id: E3HA99
names: Similarity
messages: Belongs to the ABC transporter superfamily.

572544:ILYOP RS12980
gene id: 572544:ILYOP_RS12980
uniprot id: E3HBX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

572544:ILYOP RS06185
gene id: 572544:ILYOP_RS06185
uniprot id: E3H8M7
names: Similarity
messages: Belongs to the MlaA family.

572544:ILYOP RS13810
gene id: 572544:ILYOP_RS13810
uniprot id: E3HCR7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

572544:ILYOP RS05990
gene id: 572544:ILYOP_RS05990
uniprot id: E3H8I6
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

572544:ILYOP RS02270
gene id: 572544:ILYOP_RS02270
uniprot id: E3HB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS14700
gene id: 572544:ILYOP_RS14700
uniprot id: E3HE02
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

572544:ILYOP RS06995
gene id: 572544:ILYOP_RS06995
uniprot id: E3HAI2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

572544:ILYOP RS10210
gene id: 572544:ILYOP_RS10210
uniprot id: E3HBG0
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS02970
gene id: 572544:ILYOP_RS02970
uniprot id: E3H6E9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

572544:ILYOP RS09735
gene id: 572544:ILYOP_RS09735
uniprot id: E3HAE4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS09160
gene id: 572544:ILYOP_RS09160
uniprot id: E3H9R0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS00825
gene id: 572544:ILYOP_RS00825
uniprot id: E3H747
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS03435
gene id: 572544:ILYOP_RS03435
uniprot id: E3H6T7
names: Similarity
messages: Belongs to the threonine synthase family.

572544:ILYOP RS06915
gene id: 572544:ILYOP_RS06915
uniprot id: E3HA25
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

572544:ILYOP RS02880
gene id: 572544:ILYOP_RS02880
uniprot id: E3H6D1
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

572544:ILYOP RS14580
gene id: 572544:ILYOP_RS14580
uniprot id: E3HDY4
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

572544:ILYOP RS03060
gene id: 572544:ILYOP_RS03060
uniprot id: E3H6G7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

572544:ILYOP RS00365
gene id: 572544:ILYOP_RS00365
uniprot id: E3H695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS05695
gene id: 572544:ILYOP_RS05695
uniprot id: E3H7W1
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS14270
gene id: 572544:ILYOP_RS14270
uniprot id: E3HD65
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

572544:ILYOP RS04525
gene id: 572544:ILYOP_RS04525
uniprot id: E3H8A7
names: Similarity
messages: Belongs to the P(II) protein family.

572544:ILYOP RS14715
gene id: 572544:ILYOP_RS14715
uniprot id: E3HE04
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

572544:ILYOP RS07130
gene id: 572544:ILYOP_RS07130
uniprot id: E3HAK9
names: Similarity
messages: Belongs to the disproportionating enzyme family.

572544:ILYOP RS12330
gene id: 572544:ILYOP_RS12330
uniprot id: E3HDI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

572544:ILYOP RS07700
gene id: 572544:ILYOP_RS07700
uniprot id: E3H8P6
names: Similarity
messages: Belongs to the BMP lipoprotein family.

572544:ILYOP RS04670
gene id: 572544:ILYOP_RS04670
uniprot id: E3H8D3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

572544:ILYOP RS08675
gene id: 572544:ILYOP_RS08675
uniprot id: E3HA93
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

572544:ILYOP RS00820
gene id: 572544:ILYOP_RS00820
uniprot id: E3H746
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

572544:ILYOP RS04420
gene id: 572544:ILYOP_RS04420
uniprot id: E3H7R9
names: Similarity
messages: Belongs to the ribF family.

572544:ILYOP RS10285
gene id: 572544:ILYOP_RS10285
uniprot id: E3HBG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

572544:ILYOP RS05995
gene id: 572544:ILYOP_RS05995
uniprot id: E3H8I7
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

572544:ILYOP RS10245
gene id: 572544:ILYOP_RS10245
uniprot id: E3HBG3
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS01000
gene id: 572544:ILYOP_RS01000
uniprot id: E3H7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

572544:ILYOP RS04125
gene id: 572544:ILYOP_RS04125
uniprot id: E3H7B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

572544:ILYOP RS09115
gene id: 572544:ILYOP_RS09115
uniprot id: E3H926
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

572544:ILYOP RS07005
gene id: 572544:ILYOP_RS07005
uniprot id: E3HAI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

572544:ILYOP RS00020
gene id: 572544:ILYOP_RS00020
uniprot id: E3H634
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

572544:ILYOP RS03140
gene id: 572544:ILYOP_RS03140
uniprot id: E3H6M8
names: Similarity
messages: Belongs to the Skp family.

572544:ILYOP RS06365
gene id: 572544:ILYOP_RS06365
uniprot id: E3H9D5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

572544:ILYOP RS14125
gene id: 572544:ILYOP_RS14125
uniprot id: E3HD45
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

572544:ILYOP RS03470
gene id: 572544:ILYOP_RS03470
uniprot id: E3H6U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

572544:ILYOP RS02910
gene id: 572544:ILYOP_RS02910
uniprot id: E3H6D7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

572544:ILYOP RS00380
gene id: 572544:ILYOP_RS00380
uniprot id: E3H698
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

572544:ILYOP RS06895
gene id: 572544:ILYOP_RS06895
uniprot id: E3HA21
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

572544:ILYOP RS12715
gene id: 572544:ILYOP_RS12715
uniprot id: E3HDR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

572544:ILYOP RS13330
gene id: 572544:ILYOP_RS13330
uniprot id: E3HCA8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

572544:ILYOP RS15180
gene id: 572544:ILYOP_RS15180
uniprot id: E3H9J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

572544:ILYOP RS01590
gene id: 572544:ILYOP_RS01590
uniprot id: E3HAT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

572544:ILYOP RS09665
gene id: 572544:ILYOP_RS09665
uniprot id: E3HAD4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

572544:ILYOP RS12120
gene id: 572544:ILYOP_RS12120
uniprot id: E3HDC9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

572544:ILYOP RS05890
gene id: 572544:ILYOP_RS05890
uniprot id: E3H7Z7
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

572544:ILYOP RS04490
gene id: 572544:ILYOP_RS04490
uniprot id: E3H7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

572544:ILYOP RS07280
gene id: 572544:ILYOP_RS07280
uniprot id: E3HAN9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

572544:ILYOP RS02670
gene id: 572544:ILYOP_RS02670
uniprot id: E3H612
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

572544:ILYOP RS14335
gene id: 572544:ILYOP_RS14335
uniprot id: E3HDE5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

572544:ILYOP RS12705
gene id: 572544:ILYOP_RS12705
uniprot id: E3HDQ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS08510
gene id: 572544:ILYOP_RS08510
uniprot id: E3HA60
names: Similarity
messages: Belongs to the thioredoxin family.

572544:ILYOP RS02180
gene id: 572544:ILYOP_RS02180
uniprot id: E3HB53
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS00865
gene id: 572544:ILYOP_RS00865
uniprot id: E3H7J7
names: Similarity
messages: Belongs to the bacterial secretin family.

572544:ILYOP RS05615
gene id: 572544:ILYOP_RS05615
uniprot id: E3H7U5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

572544:ILYOP RS12285
gene id: 572544:ILYOP_RS12285
uniprot id: E3HDH5
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

572544:ILYOP RS06840
gene id: 572544:ILYOP_RS06840
uniprot id: E3HA10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

572544:ILYOP RS07475
gene id: 572544:ILYOP_RS07475
uniprot id: E3H835
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

572544:ILYOP RS03525
gene id: 572544:ILYOP_RS03525
uniprot id: E3H6V5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

572544:ILYOP RS08775
gene id: 572544:ILYOP_RS08775
uniprot id: E3H8W4
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

572544:ILYOP RS07435
gene id: 572544:ILYOP_RS07435
uniprot id: E3H827
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

572544:ILYOP RS08535
gene id: 572544:ILYOP_RS08535
uniprot id: E3HA65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS00725
gene id: 572544:ILYOP_RS00725
uniprot id: E3H727
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS08505
gene id: 572544:ILYOP_RS08505
uniprot id: E3HA59
names: Similarity
messages: Belongs to the thioredoxin family.

572544:ILYOP RS13795
gene id: 572544:ILYOP_RS13795
uniprot id: E3HCR4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

572544:ILYOP RS09620
gene id: 572544:ILYOP_RS09620
uniprot id: E3HAC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS14040
gene id: 572544:ILYOP_RS14040
uniprot id: E3HD29
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

572544:ILYOP RS01460
gene id: 572544:ILYOP_RS01460
uniprot id: E3HAR0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

572544:ILYOP RS12775
gene id: 572544:ILYOP_RS12775
uniprot id: E3HDS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

572544:ILYOP RS07895
gene id: 572544:ILYOP_RS07895
uniprot id: E3H8T2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

572544:ILYOP RS06925
gene id: 572544:ILYOP_RS06925
uniprot id: E3HA27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

572544:ILYOP RS00465
gene id: 572544:ILYOP_RS00465
uniprot id: E3H6I6
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS12960
gene id: 572544:ILYOP_RS12960
uniprot id: E3HBX0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

572544:ILYOP RS00095
gene id: 572544:ILYOP_RS00095
uniprot id: E3H649
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

572544:ILYOP RS10350
gene id: 572544:ILYOP_RS10350
uniprot id: E3HBI2
names: Similarity
messages: Belongs to the class-I fumarase family.

572544:ILYOP RS05795
gene id: 572544:ILYOP_RS05795
uniprot id: E3H7Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

572544:ILYOP RS07710
gene id: 572544:ILYOP_RS07710
uniprot id: E3H8P7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

572544:ILYOP RS08930
gene id: 572544:ILYOP_RS08930
uniprot id: E3H8Y9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS00550
gene id: 572544:ILYOP_RS00550
uniprot id: E3H6K3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

572544:ILYOP RS01125
gene id: 572544:ILYOP_RS01125
uniprot id: E3H898
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

572544:ILYOP RS04760
gene id: 572544:ILYOP_RS04760
uniprot id: E3H8F2
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS03840
gene id: 572544:ILYOP_RS03840
uniprot id: E3H757
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

572544:ILYOP RS02805
gene id: 572544:ILYOP_RS02805
uniprot id: E3H6B6
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

572544:ILYOP RS06260
gene id: 572544:ILYOP_RS06260
uniprot id: E3H8P1
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS12345
gene id: 572544:ILYOP_RS12345
uniprot id: E3HDI7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS01120
gene id: 572544:ILYOP_RS01120
uniprot id: E3H897
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

572544:ILYOP RS08840
gene id: 572544:ILYOP_RS08840
uniprot id: E3H8X1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

572544:ILYOP RS03820
gene id: 572544:ILYOP_RS03820
uniprot id: E3H715
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS00090
gene id: 572544:ILYOP_RS00090
uniprot id: E3H648
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

572544:ILYOP RS12805
gene id: 572544:ILYOP_RS12805
uniprot id: E3HDS9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
messages: Belongs to the arginase family.

572544:ILYOP RS02725
gene id: 572544:ILYOP_RS02725
uniprot id: E3H623
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

572544:ILYOP RS07010
gene id: 572544:ILYOP_RS07010
uniprot id: E3HAI5
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS02810
gene id: 572544:ILYOP_RS02810
uniprot id: E3H6B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

572544:ILYOP RS06875
gene id: 572544:ILYOP_RS06875
uniprot id: E3HA17
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

572544:ILYOP RS07110
gene id: 572544:ILYOP_RS07110
uniprot id: E3HAK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

572544:ILYOP RS04230
gene id: 572544:ILYOP_RS04230
uniprot id: E3H7N3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

572544:ILYOP RS14980
gene id: 572544:ILYOP_RS14980
uniprot id: E3HE52
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

572544:ILYOP RS09810
gene id: 572544:ILYOP_RS09810
uniprot id: E3HBJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS13065
gene id: 572544:ILYOP_RS13065
uniprot id: E3HBZ0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

572544:ILYOP RS01540
gene id: 572544:ILYOP_RS01540
uniprot id: E3HAS6
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

572544:ILYOP RS04415
gene id: 572544:ILYOP_RS04415
uniprot id: E3H7R8
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

572544:ILYOP RS14470
gene id: 572544:ILYOP_RS14470
uniprot id: E3HDW3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

572544:ILYOP RS04335
gene id: 572544:ILYOP_RS04335
uniprot id: E3H7Q3
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

572544:ILYOP RS10125
gene id: 572544:ILYOP_RS10125
uniprot id: E3HBE3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

572544:ILYOP RS06195
gene id: 572544:ILYOP_RS06195
uniprot id: E3H8M9
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

572544:ILYOP RS14460
gene id: 572544:ILYOP_RS14460
uniprot id: E3HDW1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

572544:ILYOP RS09820
gene id: 572544:ILYOP_RS09820
uniprot id: E3HBJ5
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

572544:ILYOP RS01375
gene id: 572544:ILYOP_RS01375
uniprot id: E3HAH0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

572544:ILYOP RS09515
gene id: 572544:ILYOP_RS09515
uniprot id: E3HAB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

572544:ILYOP RS03970
gene id: 572544:ILYOP_RS03970
uniprot id: E3H783
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

572544:ILYOP RS09025
gene id: 572544:ILYOP_RS09025
uniprot id: E3H908
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

572544:ILYOP RS13205
gene id: 572544:ILYOP_RS13205
uniprot id: E3HC16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

572544:ILYOP RS09155
gene id: 572544:ILYOP_RS09155
uniprot id: E3H9Q9
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS06650
gene id: 572544:ILYOP_RS06650
uniprot id: E3H9X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

572544:ILYOP RS00830
gene id: 572544:ILYOP_RS00830
uniprot id: E3H748
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

572544:ILYOP RS06070
gene id: 572544:ILYOP_RS06070
uniprot id: E3H8K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

572544:ILYOP RS12570
gene id: 572544:ILYOP_RS12570
uniprot id: E3HDN0
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS06745
gene id: 572544:ILYOP_RS06745
uniprot id: E3H9Z1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

572544:ILYOP RS11905
gene id: 572544:ILYOP_RS11905
uniprot id: E3HD86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

572544:ILYOP RS06790
gene id: 572544:ILYOP_RS06790
uniprot id: E3HA00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

572544:ILYOP RS03110
gene id: 572544:ILYOP_RS03110
uniprot id: E3H6H8
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS12130
gene id: 572544:ILYOP_RS12130
uniprot id: E3HDD1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

572544:ILYOP RS07825
gene id: 572544:ILYOP_RS07825
uniprot id: E3H8R8
names: Similarity
messages: Belongs to the UPF0597 family.

572544:ILYOP RS11965
gene id: 572544:ILYOP_RS11965
uniprot id: E3HD98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

572544:ILYOP RS11770
gene id: 572544:ILYOP_RS11770
uniprot id: E3HD02
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS06550
gene id: 572544:ILYOP_RS06550
uniprot id: E3H9H3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

572544:ILYOP RS05510
gene id: 572544:ILYOP_RS05510
uniprot id: E3H7I0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

572544:ILYOP RS07090
gene id: 572544:ILYOP_RS07090
uniprot id: E3HAK1
names: Similarity
messages: Belongs to the P(II) protein family.

572544:ILYOP RS07595
gene id: 572544:ILYOP_RS07595
uniprot id: E3H858
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

572544:ILYOP RS04895
gene id: 572544:ILYOP_RS04895
uniprot id: E3H947
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

572544:ILYOP RS14345
gene id: 572544:ILYOP_RS14345
uniprot id: E3HDE7
names: Similarity
messages: Belongs to the peptidase S24 family.

572544:ILYOP RS13800
gene id: 572544:ILYOP_RS13800
uniprot id: E3HCR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

572544:ILYOP RS12915
gene id: 572544:ILYOP_RS12915
uniprot id: E3HBW1
names: Similarity
messages: Belongs to the glutamine synthetase family.

572544:ILYOP RS10695
gene id: 572544:ILYOP_RS10695
uniprot id: E3HBV1
names: Similarity
messages: Belongs to the PrpF family.

572544:ILYOP RS01035
gene id: 572544:ILYOP_RS01035
uniprot id: E3H883
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

572544:ILYOP RS12585
gene id: 572544:ILYOP_RS12585
uniprot id: E3HDN3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

572544:ILYOP RS06720
gene id: 572544:ILYOP_RS06720
uniprot id: E3H9Y6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

572544:ILYOP RS00950
gene id: 572544:ILYOP_RS00950
uniprot id: E3H7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

572544:ILYOP RS13610
gene id: 572544:ILYOP_RS13610
uniprot id: E3HCM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

572544:ILYOP RS02360
gene id: 572544:ILYOP_RS02360
uniprot id: E3HB89
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

572544:ILYOP RS08915
gene id: 572544:ILYOP_RS08915
uniprot id: E3H8Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

572544:ILYOP RS11670
gene id: 572544:ILYOP_RS11670
uniprot id: E3HCY3
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

572544:ILYOP RS11665
gene id: 572544:ILYOP_RS11665
uniprot id: E3HCY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS12250
gene id: 572544:ILYOP_RS12250
uniprot id: E3HDG9
names: Similarity
messages: Belongs to the UPF0047 family.

572544:ILYOP RS11250
gene id: 572544:ILYOP_RS11250
uniprot id: E3HCI5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS09005
gene id: 572544:ILYOP_RS09005
uniprot id: E3H904
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

572544:ILYOP RS05575
gene id: 572544:ILYOP_RS05575
uniprot id: E3H7J3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

572544:ILYOP RS14245
gene id: 572544:ILYOP_RS14245
uniprot id: E3HD60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

572544:ILYOP RS02080
gene id: 572544:ILYOP_RS02080
uniprot id: E3HB36
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

572544:ILYOP RS12580
gene id: 572544:ILYOP_RS12580
uniprot id: E3HDN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

572544:ILYOP RS05095
gene id: 572544:ILYOP_RS05095
uniprot id: E3H989
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS10330
gene id: 572544:ILYOP_RS10330
uniprot id: E3HBH8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

572544:ILYOP RS13290
gene id: 572544:ILYOP_RS13290
uniprot id: E3HCA0
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

572544:ILYOP RS07550
gene id: 572544:ILYOP_RS07550
uniprot id: E3H849
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

572544:ILYOP RS06160
gene id: 572544:ILYOP_RS06160
uniprot id: E3H8M2
names: Similarity
messages: Belongs to the HypE family.

572544:ILYOP RS06075
gene id: 572544:ILYOP_RS06075
uniprot id: E3H8K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

572544:ILYOP RS11640
gene id: 572544:ILYOP_RS11640
uniprot id: E3HCX7
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS11660
gene id: 572544:ILYOP_RS11660
uniprot id: E3HCY1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

572544:ILYOP RS14220
gene id: 572544:ILYOP_RS14220
uniprot id: E3HD55
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS05620
gene id: 572544:ILYOP_RS05620
uniprot id: E3H7U6
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS11245
gene id: 572544:ILYOP_RS11245
uniprot id: E3HCI4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

572544:ILYOP RS01480
gene id: 572544:ILYOP_RS01480
uniprot id: E3HAR4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

572544:ILYOP RS13455
gene id: 572544:ILYOP_RS13455
uniprot id: E3HCD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS01755
gene id: 572544:ILYOP_RS01755
uniprot id: E3HAW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

572544:ILYOP RS01295
gene id: 572544:ILYOP_RS01295
uniprot id: E3HAF4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

572544:ILYOP RS14595
gene id: 572544:ILYOP_RS14595
uniprot id: E3HDY7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

572544:ILYOP RS05645
gene id: 572544:ILYOP_RS05645
uniprot id: E3H7V1
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS07345
gene id: 572544:ILYOP_RS07345
uniprot id: E3H809
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

572544:ILYOP RS11475
gene id: 572544:ILYOP_RS11475
uniprot id: E3HCU8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

572544:ILYOP RS05830
gene id: 572544:ILYOP_RS05830
uniprot id: E3H7Y8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

572544:ILYOP RS12525
gene id: 572544:ILYOP_RS12525
uniprot id: E3HDM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

572544:ILYOP RS06950
gene id: 572544:ILYOP_RS06950
uniprot id: E3HA32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

572544:ILYOP RS01325
gene id: 572544:ILYOP_RS01325
uniprot id: E3HAG0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

572544:ILYOP RS08245
gene id: 572544:ILYOP_RS08245
uniprot id: E3H9M3
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS03480
gene id: 572544:ILYOP_RS03480
uniprot id: E3H6U6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

572544:ILYOP RS08410
gene id: 572544:ILYOP_RS08410
uniprot id: E3HA40
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

572544:ILYOP RS03425
gene id: 572544:ILYOP_RS03425
uniprot id: E3H6T5
names: Similarity
messages: Belongs to the aspartokinase family.

572544:ILYOP RS13505
gene id: 572544:ILYOP_RS13505
uniprot id: E3HCE2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

572544:ILYOP RS10940
gene id: 572544:ILYOP_RS10940
uniprot id: E3HC69
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

572544:ILYOP RS02210
gene id: 572544:ILYOP_RS02210
uniprot id: E3HB59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS06670
gene id: 572544:ILYOP_RS06670
uniprot id: E3H9X8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

572544:ILYOP RS06985
gene id: 572544:ILYOP_RS06985
uniprot id: E3HAI0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

572544:ILYOP RS09130
gene id: 572544:ILYOP_RS09130
uniprot id: E3H835
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

572544:ILYOP RS08665
gene id: 572544:ILYOP_RS08665
uniprot id: E3HA91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

572544:ILYOP RS09500
gene id: 572544:ILYOP_RS09500
uniprot id: E3HAB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

572544:ILYOP RS01345
gene id: 572544:ILYOP_RS01345
uniprot id: E3HAG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS02875
gene id: 572544:ILYOP_RS02875
uniprot id: E3H6D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

572544:ILYOP RS02960
gene id: 572544:ILYOP_RS02960
uniprot id: E3H6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

572544:ILYOP RS12725
gene id: 572544:ILYOP_RS12725
uniprot id: E3HDR2
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

572544:ILYOP RS02415
gene id: 572544:ILYOP_RS02415
uniprot id: E3HBA0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

572544:ILYOP RS05550
gene id: 572544:ILYOP_RS05550
uniprot id: E3H7I8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

572544:ILYOP RS14255
gene id: 572544:ILYOP_RS14255
uniprot id: E3HD62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

572544:ILYOP RS00435
gene id: 572544:ILYOP_RS00435
uniprot id: E3H6A6
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

572544:ILYOP RS09035
gene id: 572544:ILYOP_RS09035
uniprot id: E3H910
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

572544:ILYOP RS10665
gene id: 572544:ILYOP_RS10665
uniprot id: E3HBU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS05900
gene id: 572544:ILYOP_RS05900
uniprot id: E3H7Z9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS04970
gene id: 572544:ILYOP_RS04970
uniprot id: E3H963
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

572544:ILYOP RS12625
gene id: 572544:ILYOP_RS12625
uniprot id: E3HDP1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

572544:ILYOP RS11190
gene id: 572544:ILYOP_RS11190
uniprot id: E3HCH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS03760
gene id: 572544:ILYOP_RS03760
uniprot id: E3H703
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

572544:ILYOP RS05070
gene id: 572544:ILYOP_RS05070
uniprot id: E3H984
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

572544:ILYOP RS03215
gene id: 572544:ILYOP_RS03215
uniprot id: E3H6P3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

572544:ILYOP RS11270
gene id: 572544:ILYOP_RS11270
uniprot id: E3HCI9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS00430
gene id: 572544:ILYOP_RS00430
uniprot id: E3H6A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS04235
gene id: 572544:ILYOP_RS04235
uniprot id: E3H7N4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

572544:ILYOP RS02760
gene id: 572544:ILYOP_RS02760
uniprot id: E3H630
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS09530
gene id: 572544:ILYOP_RS09530
uniprot id: E3HAB7
names: Similarity
messages: Belongs to the UPF0246 family.

572544:ILYOP RS08745
gene id: 572544:ILYOP_RS08745
uniprot id: E3H8W4
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

572544:ILYOP RS09030
gene id: 572544:ILYOP_RS09030
uniprot id: E3H909
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

572544:ILYOP RS01260
gene id: 572544:ILYOP_RS01260
uniprot id: E3H9W4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

572544:ILYOP RS00960
gene id: 572544:ILYOP_RS00960
uniprot id: E3H7L0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

572544:ILYOP RS09710
gene id: 572544:ILYOP_RS09710
uniprot id: E3HAD9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

572544:ILYOP RS07610
gene id: 572544:ILYOP_RS07610
uniprot id: E3H861
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

572544:ILYOP RS00545
gene id: 572544:ILYOP_RS00545
uniprot id: E3H6K2
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS08600
gene id: 572544:ILYOP_RS08600
uniprot id: E3HA78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

572544:ILYOP RS07240
gene id: 572544:ILYOP_RS07240
uniprot id: E3HAN1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

572544:ILYOP RS05815
gene id: 572544:ILYOP_RS05815
uniprot id: E3H7Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

572544:ILYOP RS11380
gene id: 572544:ILYOP_RS11380
uniprot id: E3HCL1
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

572544:ILYOP RS13035
gene id: 572544:ILYOP_RS13035
uniprot id: E3HBY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

572544:ILYOP RS01685
gene id: 572544:ILYOP_RS01685
uniprot id: E3HAV5
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

572544:ILYOP RS13715
gene id: 572544:ILYOP_RS13715
uniprot id: E3HCQ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS03125
gene id: 572544:ILYOP_RS03125
uniprot id: E3H6I1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

572544:ILYOP RS12790
gene id: 572544:ILYOP_RS12790
uniprot id: E3HDS6
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

572544:ILYOP RS03865
gene id: 572544:ILYOP_RS03865
uniprot id: E3H762
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS00815
gene id: 572544:ILYOP_RS00815
uniprot id: E3H745
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS12825
gene id: 572544:ILYOP_RS12825
uniprot id: E3HDT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS02720
gene id: 572544:ILYOP_RS02720
uniprot id: E3H622
names: Similarity
messages: Belongs to the DprA/Smf family.

572544:ILYOP RS09040
gene id: 572544:ILYOP_RS09040
uniprot id: E3H911
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

572544:ILYOP RS03100
gene id: 572544:ILYOP_RS03100
uniprot id: E3H6H6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

572544:ILYOP RS06920
gene id: 572544:ILYOP_RS06920
uniprot id: E3HA26
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

572544:ILYOP RS11865
gene id: 572544:ILYOP_RS11865
uniprot id: E3HD78
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

572544:ILYOP RS13790
gene id: 572544:ILYOP_RS13790
uniprot id: E3HCR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

572544:ILYOP RS03860
gene id: 572544:ILYOP_RS03860
uniprot id: E3H761
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

572544:ILYOP RS03825
gene id: 572544:ILYOP_RS03825
uniprot id: E3H754
names: Cofactor
messages: Binds 1 zinc ion per subunit.

572544:ILYOP RS09105
gene id: 572544:ILYOP_RS09105
uniprot id: E3H924
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

572544:ILYOP RS02705
gene id: 572544:ILYOP_RS02705
uniprot id: E3H619
names: Similarity
messages: Belongs to the Nudix hydrolase family.

572544:ILYOP RS05470
gene id: 572544:ILYOP_RS05470
uniprot id: E3H7H1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

572544:ILYOP RS04185
gene id: 572544:ILYOP_RS04185
uniprot id: E3H7M4
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS14780
gene id: 572544:ILYOP_RS14780
uniprot id: E3HE17
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS06020
gene id: 572544:ILYOP_RS06020
uniprot id: E3H8J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

572544:ILYOP RS05000
gene id: 572544:ILYOP_RS05000
uniprot id: E3H970
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

572544:ILYOP RS01085
gene id: 572544:ILYOP_RS01085
uniprot id: E3H891
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

572544:ILYOP RS12170
gene id: 572544:ILYOP_RS12170
uniprot id: E3HDD9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

572544:ILYOP RS03065
gene id: 572544:ILYOP_RS03065
uniprot id: E3H6G8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

572544:ILYOP RS12325
gene id: 572544:ILYOP_RS12325
uniprot id: E3HDI3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

572544:ILYOP RS14975
gene id: 572544:ILYOP_RS14975
uniprot id: E3HE51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

572544:ILYOP RS03055
gene id: 572544:ILYOP_RS03055
uniprot id: E3H6G6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

572544:ILYOP RS06740
gene id: 572544:ILYOP_RS06740
uniprot id: E3H9Z0
names: Similarity
messages: Belongs to the DEAD box helicase family.

572544:ILYOP RS08995
gene id: 572544:ILYOP_RS08995
uniprot id: E3H902
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

572544:ILYOP RS12255
gene id: 572544:ILYOP_RS12255
uniprot id: E3HDH0
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS09095
gene id: 572544:ILYOP_RS09095
uniprot id: E3H922
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

572544:ILYOP RS02395
gene id: 572544:ILYOP_RS02395
uniprot id: E3HB96
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

572544:ILYOP RS06945
gene id: 572544:ILYOP_RS06945
uniprot id: E3HA31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

572544:ILYOP RS13930
gene id: 572544:ILYOP_RS13930
uniprot id: E3HCU1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

572544:ILYOP RS09320
gene id: 572544:ILYOP_RS09320
uniprot id: E3H9T8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

572544:ILYOP RS03530
gene id: 572544:ILYOP_RS03530
uniprot id: E3H6V6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

572544:ILYOP RS02815
gene id: 572544:ILYOP_RS02815
uniprot id: E3H6B8
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

572544:ILYOP RS11180
gene id: 572544:ILYOP_RS11180
uniprot id: E3HCH3
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

572544:ILYOP RS14850
gene id: 572544:ILYOP_RS14850
uniprot id: E3HE28
names: Similarity
messages: Belongs to the type IA topoisomerase family.

572544:ILYOP RS13435
gene id: 572544:ILYOP_RS13435
uniprot id: E3HCC9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

572544:ILYOP RS13225
gene id: 572544:ILYOP_RS13225
uniprot id: E3HC20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

572544:ILYOP RS08040
gene id: 572544:ILYOP_RS08040
uniprot id: E3H8W0
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS11720
gene id: 572544:ILYOP_RS11720
uniprot id: E3HCZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

572544:ILYOP RS12290
gene id: 572544:ILYOP_RS12290
uniprot id: E3HDH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

572544:ILYOP RS11045
gene id: 572544:ILYOP_RS11045
uniprot id: E3HC92
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

572544:ILYOP RS05750
gene id: 572544:ILYOP_RS05750
uniprot id: E3H7X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

572544:ILYOP RS05120
gene id: 572544:ILYOP_RS05120
uniprot id: E3H994
names: Similarity
messages: Belongs to the Nudix hydrolase family.

572544:ILYOP RS13880
gene id: 572544:ILYOP_RS13880
uniprot id: E3HCT1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

572544:ILYOP RS03200
gene id: 572544:ILYOP_RS03200
uniprot id: E3H6P0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS12910
gene id: 572544:ILYOP_RS12910
uniprot id: E3HBW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

572544:ILYOP RS07070
gene id: 572544:ILYOP_RS07070
uniprot id: E3HAJ7
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

572544:ILYOP RS11340
gene id: 572544:ILYOP_RS11340
uniprot id: E3HCK3
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

572544:ILYOP RS06465
gene id: 572544:ILYOP_RS06465
uniprot id: E3H9F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

572544:ILYOP RS08200
gene id: 572544:ILYOP_RS08200
uniprot id: E3H9L6
names: Similarity
messages: Belongs to the HAM1 NTPase family.

572544:ILYOP RS09355
gene id: 572544:ILYOP_RS09355
uniprot id: E3H9U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

572544:ILYOP RS07655
gene id: 572544:ILYOP_RS07655
uniprot id: E3H870
names: Similarity
messages: Belongs to the UPF0102 family.

572544:ILYOP RS06460
gene id: 572544:ILYOP_RS06460
uniprot id: E3H9F4
names: Similarity
messages: Belongs to the YggT family.

572544:ILYOP RS02295
gene id: 572544:ILYOP_RS02295
uniprot id: E3HB76
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS09135
gene id: 572544:ILYOP_RS09135
uniprot id: E3H9Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

572544:ILYOP RS11405
gene id: 572544:ILYOP_RS11405
uniprot id: E3HCL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

572544:ILYOP RS11555
gene id: 572544:ILYOP_RS11555
uniprot id: E3HCW3
names: Similarity
messages: Belongs to the glutamate synthase family.

572544:ILYOP RS03845
gene id: 572544:ILYOP_RS03845
uniprot id: E3H758
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

572544:ILYOP RS13465
gene id: 572544:ILYOP_RS13465
uniprot id: E3HCD5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

572544:ILYOP RS01115
gene id: 572544:ILYOP_RS01115
uniprot id: E3H896
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

572544:ILYOP RS09370
gene id: 572544:ILYOP_RS09370
uniprot id: E3H9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

572544:ILYOP RS08530
gene id: 572544:ILYOP_RS08530
uniprot id: E3HA64
names: Similarity
messages: Belongs to the GSP E family.

572544:ILYOP RS05590
gene id: 572544:ILYOP_RS05590
uniprot id: E3H7U0
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

572544:ILYOP RS16030
gene id: 572544:ILYOP_RS16030
uniprot id: E3HA28
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS08130
gene id: 572544:ILYOP_RS08130
uniprot id: E3H9K3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

572544:ILYOP RS01885
gene id: 572544:ILYOP_RS01885
uniprot id: E3HAZ6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

572544:ILYOP RS14905
gene id: 572544:ILYOP_RS14905
uniprot id: E3HE39
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

572544:ILYOP RS07190
gene id: 572544:ILYOP_RS07190
uniprot id: E3HAM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS08455
gene id: 572544:ILYOP_RS08455
uniprot id: E3HA49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

572544:ILYOP RS04245
gene id: 572544:ILYOP_RS04245
uniprot id: E3H7N6
names: Similarity
messages: Belongs to the FBPase class 3 family.

572544:ILYOP RS02365
gene id: 572544:ILYOP_RS02365
uniprot id: E3HB90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

572544:ILYOP RS01370
gene id: 572544:ILYOP_RS01370
uniprot id: E3HAG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS03485
gene id: 572544:ILYOP_RS03485
uniprot id: E3H6U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

572544:ILYOP RS02730
gene id: 572544:ILYOP_RS02730
uniprot id: E3H624
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

572544:ILYOP RS09770
gene id: 572544:ILYOP_RS09770
uniprot id: E3HBI5
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS03120
gene id: 572544:ILYOP_RS03120
uniprot id: E3H6I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

572544:ILYOP RS02015
gene id: 572544:ILYOP_RS02015
uniprot id: E3HB23
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS05085
gene id: 572544:ILYOP_RS05085
uniprot id: E3H987
names: Similarity
messages: Belongs to the LacAB/RpiB family.

572544:ILYOP RS06415
gene id: 572544:ILYOP_RS06415
uniprot id: E3H9E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

572544:ILYOP RS03145
gene id: 572544:ILYOP_RS03145
uniprot id: E3H6M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

572544:ILYOP RS06125
gene id: 572544:ILYOP_RS06125
uniprot id: E3H8L5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

572544:ILYOP RS07880
gene id: 572544:ILYOP_RS07880
uniprot id: E3H8S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS13040
gene id: 572544:ILYOP_RS13040
uniprot id: E3HBY5
names: Similarity
messages: Belongs to the UPF0178 family.

572544:ILYOP RS09380
gene id: 572544:ILYOP_RS09380
uniprot id: E3H9V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

572544:ILYOP RS15190
gene id: 572544:ILYOP_RS15190
uniprot id: E3H9K4
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS07605
gene id: 572544:ILYOP_RS07605
uniprot id: E3H860
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

572544:ILYOP RS03170
gene id: 572544:ILYOP_RS03170
uniprot id: E3H6N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

572544:ILYOP RS12795
gene id: 572544:ILYOP_RS12795
uniprot id: E3HDS7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

572544:ILYOP RS03575
gene id: 572544:ILYOP_RS03575
uniprot id: E3H6W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

572544:ILYOP RS14985
gene id: 572544:ILYOP_RS14985
uniprot id: E3HE53
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS07580
gene id: 572544:ILYOP_RS07580
uniprot id: E3H855
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

572544:ILYOP RS03720
gene id: 572544:ILYOP_RS03720
uniprot id: E3H6Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

572544:ILYOP RS04875
gene id: 572544:ILYOP_RS04875
uniprot id: E3H8H5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

572544:ILYOP RS13260
gene id: 572544:ILYOP_RS13260
uniprot id: E3HC27
names: Similarity
messages: Belongs to the CdaR family.

572544:ILYOP RS08870
gene id: 572544:ILYOP_RS08870
uniprot id: E3H8X7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

572544:ILYOP RS00150
gene id: 572544:ILYOP_RS00150
uniprot id: E3H660
names: Similarity
messages: Belongs to the RutC family.

572544:ILYOP RS13910
gene id: 572544:ILYOP_RS13910
uniprot id: E3HCT7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

572544:ILYOP RS10315
gene id: 572544:ILYOP_RS10315
uniprot id: E3HBH5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

572544:ILYOP RS07545
gene id: 572544:ILYOP_RS07545
uniprot id: E3H848
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

572544:ILYOP RS02320
gene id: 572544:ILYOP_RS02320
uniprot id: E3HB81
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

572544:ILYOP RS07125
gene id: 572544:ILYOP_RS07125
uniprot id: E3HAK8
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

572544:ILYOP RS14045
gene id: 572544:ILYOP_RS14045
uniprot id: E3HD30
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

572544:ILYOP RS01110
gene id: 572544:ILYOP_RS01110
uniprot id: E3H895
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

572544:ILYOP RS08835
gene id: 572544:ILYOP_RS08835
uniprot id: E3H8X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

572544:ILYOP RS09705
gene id: 572544:ILYOP_RS09705
uniprot id: E3HAD8
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

572544:ILYOP RS07265
gene id: 572544:ILYOP_RS07265
uniprot id: E3HAN6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

572544:ILYOP RS07500
gene id: 572544:ILYOP_RS07500
uniprot id: E3H837
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

572544:ILYOP RS13630
gene id: 572544:ILYOP_RS13630
uniprot id: E3HCN1
names: Similarity
messages: Belongs to the aspartokinase family.

572544:ILYOP RS01330
gene id: 572544:ILYOP_RS01330
uniprot id: E3HAG1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

572544:ILYOP RS02525
gene id: 572544:ILYOP_RS02525
uniprot id: E3H5Y3
names: Similarity
messages: Belongs to the RecJ family.

572544:ILYOP RS04050
gene id: 572544:ILYOP_RS04050
uniprot id: E3H798
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

572544:ILYOP RS05940
gene id: 572544:ILYOP_RS05940
uniprot id: E3H807
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

572544:ILYOP RS05030
gene id: 572544:ILYOP_RS05030
uniprot id: E3H976
names: Similarity
messages: Belongs to the UPF0173 family.

572544:ILYOP RS01515
gene id: 572544:ILYOP_RS01515
uniprot id: E3HAS1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

572544:ILYOP RS13595
gene id: 572544:ILYOP_RS13595
uniprot id: E3HCF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

572544:ILYOP RS13625
gene id: 572544:ILYOP_RS13625
uniprot id: E3HCN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS07905
gene id: 572544:ILYOP_RS07905
uniprot id: E3H8T4
names: Similarity
messages: Belongs to the YjdM family.

572544:ILYOP RS01010
gene id: 572544:ILYOP_RS01010
uniprot id: E3H878
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

572544:ILYOP RS00425
gene id: 572544:ILYOP_RS00425
uniprot id: E3H6A4
names: Similarity
messages: Belongs to the UxaA family.

572544:ILYOP RS09385
gene id: 572544:ILYOP_RS09385
uniprot id: E3H9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

572544:ILYOP RS03700
gene id: 572544:ILYOP_RS03700
uniprot id: E3H6Z1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

572544:ILYOP RS09055
gene id: 572544:ILYOP_RS09055
uniprot id: E3H914
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

572544:ILYOP RS02830
gene id: 572544:ILYOP_RS02830
uniprot id: E3H6C1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

572544:ILYOP RS02935
gene id: 572544:ILYOP_RS02935
uniprot id: E3H6E2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

572544:ILYOP RS02710
gene id: 572544:ILYOP_RS02710
uniprot id: E3H620
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

572544:ILYOP RS00995
gene id: 572544:ILYOP_RS00995
uniprot id: E3H7L7
names: Similarity
messages: Belongs to the RemA family.

572544:ILYOP RS02940
gene id: 572544:ILYOP_RS02940
uniprot id: E3H6E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

572544:ILYOP RS05325
gene id: 572544:ILYOP_RS05325
uniprot id: E3H7D9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

572544:ILYOP RS10735
gene id: 572544:ILYOP_RS10735
uniprot id: E3HC29
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

572544:ILYOP RS07440
gene id: 572544:ILYOP_RS07440
uniprot id: E3H828
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS04975
gene id: 572544:ILYOP_RS04975
uniprot id: E3H964
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

572544:ILYOP RS08185
gene id: 572544:ILYOP_RS08185
uniprot id: E3H9L3
names: Similarity
messages: Belongs to the UPF0237 family.

572544:ILYOP RS07200
gene id: 572544:ILYOP_RS07200
uniprot id: E3HAM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS06175
gene id: 572544:ILYOP_RS06175
uniprot id: E3H8M5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

572544:ILYOP RS04295
gene id: 572544:ILYOP_RS04295
uniprot id: E3H7P6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

572544:ILYOP RS10295
gene id: 572544:ILYOP_RS10295
uniprot id: E3HBH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

572544:ILYOP RS05985
gene id: 572544:ILYOP_RS05985
uniprot id: E3H8I5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

572544:ILYOP RS06220
gene id: 572544:ILYOP_RS06220
uniprot id: E3H8N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

572544:ILYOP RS08445
gene id: 572544:ILYOP_RS08445
uniprot id: E3HA47
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

572544:ILYOP RS07745
gene id: 572544:ILYOP_RS07745
uniprot id: E3H8Q4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

572544:ILYOP RS00265
gene id: 572544:ILYOP_RS00265
uniprot id: E3H675
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

572544:ILYOP RS14360
gene id: 572544:ILYOP_RS14360
uniprot id: E3HDF0
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

572544:ILYOP RS07900
gene id: 572544:ILYOP_RS07900
uniprot id: E3H8T3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

572544:ILYOP RS06785
gene id: 572544:ILYOP_RS06785
uniprot id: E3H9Z9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

572544:ILYOP RS12590
gene id: 572544:ILYOP_RS12590
uniprot id: E3HDN4
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

572544:ILYOP RS07375
gene id: 572544:ILYOP_RS07375
uniprot id: E3H815
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

572544:ILYOP RS08575
gene id: 572544:ILYOP_RS08575
uniprot id: E3HA73
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS12165
gene id: 572544:ILYOP_RS12165
uniprot id: E3HDD8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

572544:ILYOP RS07260
gene id: 572544:ILYOP_RS07260
uniprot id: E3HAN5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

572544:ILYOP RS06545
gene id: 572544:ILYOP_RS06545
uniprot id: E3H9H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

572544:ILYOP RS02280
gene id: 572544:ILYOP_RS02280
uniprot id: E3HB73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

572544:ILYOP RS08255
gene id: 572544:ILYOP_RS08255
uniprot id: E3H9M5
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

572544:ILYOP RS09295
gene id: 572544:ILYOP_RS09295
uniprot id: E3H9T3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

572544:ILYOP RS02275
gene id: 572544:ILYOP_RS02275
uniprot id: E3HB72
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

572544:ILYOP RS01800
gene id: 572544:ILYOP_RS01800
uniprot id: E3HAY0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS10135
gene id: 572544:ILYOP_RS10135
uniprot id: E3HBE5
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

572544:ILYOP RS09045
gene id: 572544:ILYOP_RS09045
uniprot id: E3H912
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

572544:ILYOP RS07170
gene id: 572544:ILYOP_RS07170
uniprot id: E3HAL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS09785
gene id: 572544:ILYOP_RS09785
uniprot id: E3HBI8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

572544:ILYOP RS09605
gene id: 572544:ILYOP_RS09605
uniprot id: E3HAC1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

572544:ILYOP RS11655
gene id: 572544:ILYOP_RS11655
uniprot id: E3HCY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

572544:ILYOP RS01625
gene id: 572544:ILYOP_RS01625
uniprot id: E3HAU2
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

572544:ILYOP RS11470
gene id: 572544:ILYOP_RS11470
uniprot id: E3HCU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

572544:ILYOP RS00630
gene id: 572544:ILYOP_RS00630
uniprot id: E3H6L9
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS14785
gene id: 572544:ILYOP_RS14785
uniprot id: E3HE18
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

572544:ILYOP RS00080
gene id: 572544:ILYOP_RS00080
uniprot id: E3H646
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

572544:ILYOP RS05300
gene id: 572544:ILYOP_RS05300
uniprot id: E3H7D3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

572544:ILYOP RS07100
gene id: 572544:ILYOP_RS07100
uniprot id: E3HAK3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-103 inactivates the nitrogenase reductase and regulates nitrogenase activity.

572544:ILYOP RS08365
gene id: 572544:ILYOP_RS08365
uniprot id: E3H9P7
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS09050
gene id: 572544:ILYOP_RS09050
uniprot id: E3H913
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

572544:ILYOP RS04520
gene id: 572544:ILYOP_RS04520
uniprot id: E3H8A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS13270
gene id: 572544:ILYOP_RS13270
uniprot id: E3HC96
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

572544:ILYOP RS11460
gene id: 572544:ILYOP_RS11460
uniprot id: E3HCM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

572544:ILYOP RS13600
gene id: 572544:ILYOP_RS13600
uniprot id: E3HCG0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

572544:ILYOP RS12095
gene id: 572544:ILYOP_RS12095
uniprot id: E3HDC4
names: Similarity
messages: Belongs to the CobH/CbiC family.

572544:ILYOP RS02400
gene id: 572544:ILYOP_RS02400
uniprot id: E3HB97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

572544:ILYOP RS12080
gene id: 572544:ILYOP_RS12080
uniprot id: E3HDC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

572544:ILYOP RS14465
gene id: 572544:ILYOP_RS14465
uniprot id: E3HDW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

572544:ILYOP RS00060
gene id: 572544:ILYOP_RS00060
uniprot id: E3H642
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

572544:ILYOP RS12350
gene id: 572544:ILYOP_RS12350
uniprot id: E3HDI8
names: Similarity
messages: Belongs to the TrpC family.

572544:ILYOP RS05585
gene id: 572544:ILYOP_RS05585
uniprot id: E3H7J5
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS14955
gene id: 572544:ILYOP_RS14955
uniprot id: E3HE47
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS01915
gene id: 572544:ILYOP_RS01915
uniprot id: E3HB03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

572544:ILYOP RS09085
gene id: 572544:ILYOP_RS09085
uniprot id: E3H920
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

572544:ILYOP RS05075
gene id: 572544:ILYOP_RS05075
uniprot id: E3H985
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

572544:ILYOP RS03815
gene id: 572544:ILYOP_RS03815
uniprot id: E3H714
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

572544:ILYOP RS06805
gene id: 572544:ILYOP_RS06805
uniprot id: E3HA03
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

572544:ILYOP RS00065
gene id: 572544:ILYOP_RS00065
uniprot id: E3H643
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

572544:ILYOP RS11645
gene id: 572544:ILYOP_RS11645
uniprot id: E3HCX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

572544:ILYOP RS05685
gene id: 572544:ILYOP_RS05685
uniprot id: E3H7V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

572544:ILYOP RS03410
gene id: 572544:ILYOP_RS03410
uniprot id: E3H6T2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

572544:ILYOP RS11320
gene id: 572544:ILYOP_RS11320
uniprot id: E3HCJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS07615
gene id: 572544:ILYOP_RS07615
uniprot id: E3H862
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

572544:ILYOP RS00940
gene id: 572544:ILYOP_RS00940
uniprot id: E3H7K7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

572544:ILYOP RS07165
gene id: 572544:ILYOP_RS07165
uniprot id: E3HAL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

572544:ILYOP RS06485
gene id: 572544:ILYOP_RS06485
uniprot id: E3H9G0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS11135
gene id: 572544:ILYOP_RS11135
uniprot id: E3HCG4
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS07095
gene id: 572544:ILYOP_RS07095
uniprot id: E3HAK2
names: Similarity
messages: Belongs to the P(II) protein family.

572544:ILYOP RS08610
gene id: 572544:ILYOP_RS08610
uniprot id: E3HA80
names: Similarity
messages: Belongs to the TlyA family.

572544:ILYOP RS01335
gene id: 572544:ILYOP_RS01335
uniprot id: E3HAG2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

572544:ILYOP RS13620
gene id: 572544:ILYOP_RS13620
uniprot id: E3HCM9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS07585
gene id: 572544:ILYOP_RS07585
uniprot id: E3H856
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

572544:ILYOP RS01960
gene id: 572544:ILYOP_RS01960
uniprot id: E3HB12
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

572544:ILYOP RS06560
gene id: 572544:ILYOP_RS06560
uniprot id: E3H9H5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

572544:ILYOP RS11795
gene id: 572544:ILYOP_RS11795
uniprot id: E3HD07
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

572544:ILYOP RS14250
gene id: 572544:ILYOP_RS14250
uniprot id: E3HD61
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

572544:ILYOP RS01955
gene id: 572544:ILYOP_RS01955
uniprot id: E3HB11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

572544:ILYOP RS07955
gene id: 572544:ILYOP_RS07955
uniprot id: E3H8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS07855
gene id: 572544:ILYOP_RS07855
uniprot id: E3H8S4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

572544:ILYOP RS01230
gene id: 572544:ILYOP_RS01230
uniprot id: E3H943
names: Similarity
messages: Belongs to the peptidase M24B family.

572544:ILYOP RS03790
gene id: 572544:ILYOP_RS03790
uniprot id: E3H709
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

572544:ILYOP RS04090
gene id: 572544:ILYOP_RS04090
uniprot id: E3H7A6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS04780
gene id: 572544:ILYOP_RS04780
uniprot id: E3H8F6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

572544:ILYOP RS01745
gene id: 572544:ILYOP_RS01745
uniprot id: E3HAW7
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS08850
gene id: 572544:ILYOP_RS08850
uniprot id: E3H8X3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

572544:ILYOP RS03130
gene id: 572544:ILYOP_RS03130
uniprot id: E3H6I2
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS12840
gene id: 572544:ILYOP_RS12840
uniprot id: E3HDT6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

572544:ILYOP RS05725
gene id: 572544:ILYOP_RS05725
uniprot id: E3H7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

572544:ILYOP RS13770
gene id: 572544:ILYOP_RS13770
uniprot id: E3HCQ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

572544:ILYOP RS10395
gene id: 572544:ILYOP_RS10395
uniprot id: E3HBP3
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

572544:ILYOP RS02205
gene id: 572544:ILYOP_RS02205
uniprot id: E3HB58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS11265
gene id: 572544:ILYOP_RS11265
uniprot id: E3HCI8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

572544:ILYOP RS13890
gene id: 572544:ILYOP_RS13890
uniprot id: E3HAT8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

572544:ILYOP RS09290
gene id: 572544:ILYOP_RS09290
uniprot id: E3H9T2
names: Caution
names: Function
names: Similarity
messages: Belongs to the MrnC RNase family.
messages: Might be a ribonuclease involved in RNA processing.
messages: Strongly resembles the MrnC Mini-3 enzyme, but is missing a highly conserved, possibly catalytically important site at position 72.

572544:ILYOP RS01550
gene id: 572544:ILYOP_RS01550
uniprot id: E3HAS8
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

572544:ILYOP RS05405
gene id: 572544:ILYOP_RS05405
uniprot id: E3H7F8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

572544:ILYOP RS13215
gene id: 572544:ILYOP_RS13215
uniprot id: E3HC18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

572544:ILYOP RS00955
gene id: 572544:ILYOP_RS00955
uniprot id: E3H7K9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

572544:ILYOP RS11285
gene id: 572544:ILYOP_RS11285
uniprot id: E3HCJ2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

572544:ILYOP RS05625
gene id: 572544:ILYOP_RS05625
uniprot id: E3H7U7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

572544:ILYOP RS13240
gene id: 572544:ILYOP_RS13240
uniprot id: E3HC23
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

572544:ILYOP RS13900
gene id: 572544:ILYOP_RS13900
uniprot id: E3HCT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

572544:ILYOP RS07370
gene id: 572544:ILYOP_RS07370
uniprot id: E3H814
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

572544:ILYOP RS14120
gene id: 572544:ILYOP_RS14120
uniprot id: E3HD44
names: Cofactor
messages: Binds 1 FMN per subunit.

572544:ILYOP RS07335
gene id: 572544:ILYOP_RS07335
uniprot id: E3HAQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS15115
gene id: 572544:ILYOP_RS15115
uniprot id: E3H8C4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

572544:ILYOP RS01445
gene id: 572544:ILYOP_RS01445
uniprot id: E3HAQ7
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS11940
gene id: 572544:ILYOP_RS11940
uniprot id: E3HD93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

572544:ILYOP RS08895
gene id: 572544:ILYOP_RS08895
uniprot id: E3H8Y2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

572544:ILYOP RS12040
gene id: 572544:ILYOP_RS12040
uniprot id: E3HDB3
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

572544:ILYOP RS03570
gene id: 572544:ILYOP_RS03570
uniprot id: E3H6W4
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

572544:ILYOP RS01935
gene id: 572544:ILYOP_RS01935
uniprot id: E3HB07
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS07390
gene id: 572544:ILYOP_RS07390
uniprot id: E3H818
names: Similarity
messages: Belongs to the asp23 family.

572544:ILYOP RS13315
gene id: 572544:ILYOP_RS13315
uniprot id: E3HCA5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

572544:ILYOP RS13310
gene id: 572544:ILYOP_RS13310
uniprot id: E3HCA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

572544:ILYOP RS07720
gene id: 572544:ILYOP_RS07720
uniprot id: E3H8P9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

572544:ILYOP RS05445
gene id: 572544:ILYOP_RS05445
uniprot id: E3H7G6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

572544:ILYOP RS10265
gene id: 572544:ILYOP_RS10265
uniprot id: E3HBG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS08855
gene id: 572544:ILYOP_RS08855
uniprot id: E3H8X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

572544:ILYOP RS09750
gene id: 572544:ILYOP_RS09750
uniprot id: E3HAE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

572544:ILYOP RS15080
gene id: 572544:ILYOP_RS15080
uniprot id: E3H6B2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

572544:ILYOP RS01305
gene id: 572544:ILYOP_RS01305
uniprot id: E3HAF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

572544:ILYOP RS12215
gene id: 572544:ILYOP_RS12215
uniprot id: E3HDG2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

572544:ILYOP RS12695
gene id: 572544:ILYOP_RS12695
uniprot id: E3HDQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

572544:ILYOP RS13555
gene id: 572544:ILYOP_RS13555
uniprot id: E3HCF1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

572544:ILYOP RS12540
gene id: 572544:ILYOP_RS12540
uniprot id: E3HDM5
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS01730
gene id: 572544:ILYOP_RS01730
uniprot id: E3HAW4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

572544:ILYOP RS15330
gene id: 572544:ILYOP_RS15330
uniprot id: E3HDL8
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS03075
gene id: 572544:ILYOP_RS03075
uniprot id: E3H6H1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

572544:ILYOP RS14560
gene id: 572544:ILYOP_RS14560
uniprot id: E3HDY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

572544:ILYOP RS03450
gene id: 572544:ILYOP_RS03450
uniprot id: E3H6U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

572544:ILYOP RS01015
gene id: 572544:ILYOP_RS01015
uniprot id: E3H879
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

572544:ILYOP RS01795
gene id: 572544:ILYOP_RS01795
uniprot id: E3HAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

572544:ILYOP RS04045
gene id: 572544:ILYOP_RS04045
uniprot id: E3H797
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS13650
gene id: 572544:ILYOP_RS13650
uniprot id: E3HCN5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

572544:ILYOP RS07045
gene id: 572544:ILYOP_RS07045
uniprot id: E3HAJ2
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

572544:ILYOP RS15040
gene id: 572544:ILYOP_RS15040
uniprot id: E3HAV8
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS03225
gene id: 572544:ILYOP_RS03225
uniprot id: E3H6P5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

572544:ILYOP RS02845
gene id: 572544:ILYOP_RS02845
uniprot id: E3H6C4
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

572544:ILYOP RS12430
gene id: 572544:ILYOP_RS12430
uniprot id: E3HDK3
names: Subcellular Location Annotation
messages: Cytoplasm

572544:ILYOP RS12150
gene id: 572544:ILYOP_RS12150
uniprot id: E3HDD5
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

572544:ILYOP RS00730
gene id: 572544:ILYOP_RS00730
uniprot id: E3H728
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS05675
gene id: 572544:ILYOP_RS05675
uniprot id: E3H7V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

572544:ILYOP RS01500
gene id: 572544:ILYOP_RS01500
uniprot id: E3HAR8
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

572544:ILYOP RS11890
gene id: 572544:ILYOP_RS11890
uniprot id: E3HD83
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

572544:ILYOP RS06855
gene id: 572544:ILYOP_RS06855
uniprot id: E3HA13
names: Similarity
messages: Belongs to the FBPase class 2 family.

572544:ILYOP RS03775
gene id: 572544:ILYOP_RS03775
uniprot id: E3H706
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

572544:ILYOP RS13275
gene id: 572544:ILYOP_RS13275
uniprot id: E3HC97
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS08250
gene id: 572544:ILYOP_RS08250
uniprot id: E3H9M4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

572544:ILYOP RS12260
gene id: 572544:ILYOP_RS12260
uniprot id: E3HDH1
names: Subcellular Location Annotation
messages: Cytoplasm

572544:ILYOP RS02135
gene id: 572544:ILYOP_RS02135
uniprot id: E3HB44
names: Similarity
messages: Belongs to the AlaDH/PNT family.

572544:ILYOP RS09365
gene id: 572544:ILYOP_RS09365
uniprot id: E3H9U7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS03370
gene id: 572544:ILYOP_RS03370
uniprot id: E3H6S4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

572544:ILYOP RS10890
gene id: 572544:ILYOP_RS10890
uniprot id: E3HC59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

572544:ILYOP RS14695
gene id: 572544:ILYOP_RS14695
uniprot id: E3HE01
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

572544:ILYOP RS08780
gene id: 572544:ILYOP_RS08780
uniprot id: E3H8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

572544:ILYOP RS09690
gene id: 572544:ILYOP_RS09690
uniprot id: E3HAD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS07690
gene id: 572544:ILYOP_RS07690
uniprot id: E3H877
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

572544:ILYOP RS08925
gene id: 572544:ILYOP_RS08925
uniprot id: E3H8Y8
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

572544:ILYOP RS02675
gene id: 572544:ILYOP_RS02675
uniprot id: E3H613
names: Similarity
messages: Belongs to the UPF0758 family.

572544:ILYOP RS01825
gene id: 572544:ILYOP_RS01825
uniprot id: E3HAY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

572544:ILYOP RS13635
gene id: 572544:ILYOP_RS13635
uniprot id: E3HCN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

572544:ILYOP RS00705
gene id: 572544:ILYOP_RS00705
uniprot id: E3H723
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

572544:ILYOP RS00250
gene id: 572544:ILYOP_RS00250
uniprot id: E3H671
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

572544:ILYOP RS01985
gene id: 572544:ILYOP_RS01985
uniprot id: E3HB17
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS03085
gene id: 572544:ILYOP_RS03085
uniprot id: E3H6H3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

572544:ILYOP RS14280
gene id: 572544:ILYOP_RS14280
uniprot id: E3HD67
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

572544:ILYOP RS02155
gene id: 572544:ILYOP_RS02155
uniprot id: E3HB48
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

572544:ILYOP RS15650
gene id: 572544:ILYOP_RS15650
uniprot id: E3HCI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

572544:ILYOP RS09240
gene id: 572544:ILYOP_RS09240
uniprot id: E3H9S6
names: Similarity
messages: Belongs to the GSP E family.

572544:ILYOP RS06395
gene id: 572544:ILYOP_RS06395
uniprot id: E3H9E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

572544:ILYOP RS01245
gene id: 572544:ILYOP_RS01245
uniprot id: E3H9W1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

572544:ILYOP RS11300
gene id: 572544:ILYOP_RS11300
uniprot id: E3HCJ5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS02140
gene id: 572544:ILYOP_RS02140
uniprot id: E3HB45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

572544:ILYOP RS01475
gene id: 572544:ILYOP_RS01475
uniprot id: E3HAR3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

572544:ILYOP RS02660
gene id: 572544:ILYOP_RS02660
uniprot id: E3H610
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

572544:ILYOP RS06430
gene id: 572544:ILYOP_RS06430
uniprot id: E3H9E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

572544:ILYOP RS08595
gene id: 572544:ILYOP_RS08595
uniprot id: E3HA77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

572544:ILYOP RS03285
gene id: 572544:ILYOP_RS03285
uniprot id: E3H6Q7
names: Similarity
messages: Belongs to the peptidase S49 family.

572544:ILYOP RS01005
gene id: 572544:ILYOP_RS01005
uniprot id: E3H7L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

572544:ILYOP RS14235
gene id: 572544:ILYOP_RS14235
uniprot id: E3HD58
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

572544:ILYOP RS08580
gene id: 572544:ILYOP_RS08580
uniprot id: E3HA74
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS06190
gene id: 572544:ILYOP_RS06190
uniprot id: E3H8M8
names: Similarity
messages: Belongs to the MlaA family.

572544:ILYOP RS09000
gene id: 572544:ILYOP_RS09000
uniprot id: E3H903
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

572544:ILYOP RS08935
gene id: 572544:ILYOP_RS08935
uniprot id: E3H8Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

572544:ILYOP RS11860
gene id: 572544:ILYOP_RS11860
uniprot id: E3HD77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

572544:ILYOP RS04710
gene id: 572544:ILYOP_RS04710
uniprot id: E3H8E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

572544:ILYOP RS08590
gene id: 572544:ILYOP_RS08590
uniprot id: E3HA76
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS13875
gene id: 572544:ILYOP_RS13875
uniprot id: E3HCT0
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS02885
gene id: 572544:ILYOP_RS02885
uniprot id: E3H6D2
names: Subcellular Location Annotation
messages: Cytoplasm

572544:ILYOP RS00360
gene id: 572544:ILYOP_RS00360
uniprot id: E3H694
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS16035
gene id: 572544:ILYOP_RS16035
uniprot id: E3HA29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

572544:ILYOP RS12735
gene id: 572544:ILYOP_RS12735
uniprot id: E3HDR4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

572544:ILYOP RS01680
gene id: 572544:ILYOP_RS01680
uniprot id: E3HAV4
names: Similarity
messages: Belongs to the PrpF family.

572544:ILYOP RS10710
gene id: 572544:ILYOP_RS10710
uniprot id: E3HBV4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

572544:ILYOP RS06010
gene id: 572544:ILYOP_RS06010
uniprot id: E3H8J0
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS06375
gene id: 572544:ILYOP_RS06375
uniprot id: E3H9D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

572544:ILYOP RS09090
gene id: 572544:ILYOP_RS09090
uniprot id: E3H921
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

572544:ILYOP RS05540
gene id: 572544:ILYOP_RS05540
uniprot id: E3H7I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

572544:ILYOP RS08375
gene id: 572544:ILYOP_RS08375
uniprot id: E3H9P9
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS14790
gene id: 572544:ILYOP_RS14790
uniprot id: E3HE19
names: Similarity
messages: Belongs to the TrbI/VirB10 family.

572544:ILYOP RS13280
gene id: 572544:ILYOP_RS13280
uniprot id: E3HC98
names: Similarity
messages: Belongs to the CdaR family.

572544:ILYOP RS07940
gene id: 572544:ILYOP_RS07940
uniprot id: E3H8U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

572544:ILYOP RS03750
gene id: 572544:ILYOP_RS03750
uniprot id: E3H702
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

572544:ILYOP RS15160
gene id: 572544:ILYOP_RS15160
uniprot id: E3H8J6
names: Similarity
messages: Belongs to the MipA/OmpV family.

572544:ILYOP RS11175
gene id: 572544:ILYOP_RS11175
uniprot id: E3HCH2
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

572544:ILYOP RS13080
gene id: 572544:ILYOP_RS13080
uniprot id: E3HBZ3
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

572544:ILYOP RS12115
gene id: 572544:ILYOP_RS12115
uniprot id: E3HDC8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

572544:ILYOP RS04785
gene id: 572544:ILYOP_RS04785
uniprot id: E3H8F8
names: Similarity
messages: Belongs to the aspartokinase family.

572544:ILYOP RS00315
gene id: 572544:ILYOP_RS00315
uniprot id: E3H685
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS14575
gene id: 572544:ILYOP_RS14575
uniprot id: E3HDY3
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS06080
gene id: 572544:ILYOP_RS06080
uniprot id: E3H8K4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

572544:ILYOP RS00170
gene id: 572544:ILYOP_RS00170
uniprot id: E3H664
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

572544:ILYOP RS13300
gene id: 572544:ILYOP_RS13300
uniprot id: E3HCA2
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

572544:ILYOP RS00970
gene id: 572544:ILYOP_RS00970
uniprot id: E3H7L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

572544:ILYOP RS13100
gene id: 572544:ILYOP_RS13100
uniprot id: E3HBZ7
names: Similarity
messages: Belongs to the HdrA family.

572544:ILYOP RS08715
gene id: 572544:ILYOP_RS08715
uniprot id: E3HAA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

572544:ILYOP RS09235
gene id: 572544:ILYOP_RS09235
uniprot id: E3H9S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS08570
gene id: 572544:ILYOP_RS08570
uniprot id: E3HA72
names: Similarity
messages: Belongs to the band 7/mec-2 family.

572544:ILYOP RS11240
gene id: 572544:ILYOP_RS11240
uniprot id: E3HCI3
names: Similarity
messages: Belongs to the GARS family.

572544:ILYOP RS07565
gene id: 572544:ILYOP_RS07565
uniprot id: E3H852
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

572544:ILYOP RS10250
gene id: 572544:ILYOP_RS10250
uniprot id: E3HBG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

572544:ILYOP RS13245
gene id: 572544:ILYOP_RS13245
uniprot id: E3HC24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

572544:ILYOP RS07870
gene id: 572544:ILYOP_RS07870
uniprot id: E3H8S7
names: Similarity
messages: Belongs to the peptidase C56 family.

572544:ILYOP RS05835
gene id: 572544:ILYOP_RS05835
uniprot id: E3H7Y9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS06750
gene id: 572544:ILYOP_RS06750
uniprot id: E3H9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

572544:ILYOP RS14455
gene id: 572544:ILYOP_RS14455
uniprot id: E3HDW0
names: Similarity
messages: Belongs to the rubredoxin family.

572544:ILYOP RS05400
gene id: 572544:ILYOP_RS05400
uniprot id: E3H7F7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

572544:ILYOP RS02145
gene id: 572544:ILYOP_RS02145
uniprot id: E3HB46
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS07625
gene id: 572544:ILYOP_RS07625
uniprot id: E3H864
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

572544:ILYOP RS00975
gene id: 572544:ILYOP_RS00975
uniprot id: E3H7L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

572544:ILYOP RS05425
gene id: 572544:ILYOP_RS05425
uniprot id: E3H7G2
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

572544:ILYOP RS11500
gene id: 572544:ILYOP_RS11500
uniprot id: E3HCV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS05415
gene id: 572544:ILYOP_RS05415
uniprot id: E3H7G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

572544:ILYOP RS06420
gene id: 572544:ILYOP_RS06420
uniprot id: E3H9E6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

572544:ILYOP RS08465
gene id: 572544:ILYOP_RS08465
uniprot id: E3HA51
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

572544:ILYOP RS04660
gene id: 572544:ILYOP_RS04660
uniprot id: E3H8D0
names: Similarity
messages: Belongs to the P(II) protein family.

572544:ILYOP RS04655
gene id: 572544:ILYOP_RS04655
uniprot id: E3H8C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS06905
gene id: 572544:ILYOP_RS06905
uniprot id: E3HA23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

572544:ILYOP RS00800
gene id: 572544:ILYOP_RS00800
uniprot id: E3H742
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS12875
gene id: 572544:ILYOP_RS12875
uniprot id: E3HDU3
names: Similarity
messages: Belongs to the asparaginase 1 family.

572544:ILYOP RS02945
gene id: 572544:ILYOP_RS02945
uniprot id: E3H6E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

572544:ILYOP RS01135
gene id: 572544:ILYOP_RS01135
uniprot id: E3H8A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

572544:ILYOP RS09250
gene id: 572544:ILYOP_RS09250
uniprot id: E3H9S8
names: Similarity
messages: Belongs to the GSP E family.

572544:ILYOP RS12935
gene id: 572544:ILYOP_RS12935
uniprot id: E3HBW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane
messages: Membrane

572544:ILYOP RS07075
gene id: 572544:ILYOP_RS07075
uniprot id: E3HAJ8
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

572544:ILYOP RS02635
gene id: 572544:ILYOP_RS02635
uniprot id: E3H605
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

572544:ILYOP RS09635
gene id: 572544:ILYOP_RS09635
uniprot id: E3HAC8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

572544:ILYOP RS01240
gene id: 572544:ILYOP_RS01240
uniprot id: E3H945
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS07770
gene id: 572544:ILYOP_RS07770
uniprot id: E3H8Q7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

572544:ILYOP RS01020
gene id: 572544:ILYOP_RS01020
uniprot id: E3H880
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

572544:ILYOP RS03405
gene id: 572544:ILYOP_RS03405
uniprot id: E3H6T1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

572544:ILYOP RS02700
gene id: 572544:ILYOP_RS02700
uniprot id: E3H618
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

572544:ILYOP RS12535
gene id: 572544:ILYOP_RS12535
uniprot id: E3HDM4
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS02775
gene id: 572544:ILYOP_RS02775
uniprot id: E3H6B0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

572544:ILYOP RS09645
gene id: 572544:ILYOP_RS09645
uniprot id: E3HAD0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

572544:ILYOP RS06445
gene id: 572544:ILYOP_RS06445
uniprot id: E3H9F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

572544:ILYOP RS11880
gene id: 572544:ILYOP_RS11880
uniprot id: E3HD81
names: Function
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

572544:ILYOP RS05640
gene id: 572544:ILYOP_RS05640
uniprot id: E3H7V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

572544:ILYOP RS12230
gene id: 572544:ILYOP_RS12230
uniprot id: E3HDG5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

572544:ILYOP RS06235
gene id: 572544:ILYOP_RS06235
uniprot id: E3H8N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

572544:ILYOP RS08825
gene id: 572544:ILYOP_RS08825
uniprot id: E3H8W8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

572544:ILYOP RS00775
gene id: 572544:ILYOP_RS00775
uniprot id: E3H737
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS11355
gene id: 572544:ILYOP_RS11355
uniprot id: E3HCK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

572544:ILYOP RS11275
gene id: 572544:ILYOP_RS11275
uniprot id: E3HCJ0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

572544:ILYOP RS00075
gene id: 572544:ILYOP_RS00075
uniprot id: E3H645
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

572544:ILYOP RS05905
gene id: 572544:ILYOP_RS05905
uniprot id: E3H800
names: Subcellular Location Annotation
messages: Cytoplasm

572544:ILYOP RS03515
gene id: 572544:ILYOP_RS03515
uniprot id: E3H6V3
names: Similarity
messages: Belongs to the GSP E family.

572544:ILYOP RS07635
gene id: 572544:ILYOP_RS07635
uniprot id: E3H866
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

572544:ILYOP RS00145
gene id: 572544:ILYOP_RS00145
uniprot id: E3H659
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS13025
gene id: 572544:ILYOP_RS13025
uniprot id: E3HBY2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

572544:ILYOP RS02860
gene id: 572544:ILYOP_RS02860
uniprot id: E3H6C7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

572544:ILYOP RS12045
gene id: 572544:ILYOP_RS12045
uniprot id: E3HDB4
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

572544:ILYOP RS03565
gene id: 572544:ILYOP_RS03565
uniprot id: E3H6W3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

572544:ILYOP RS05740
gene id: 572544:ILYOP_RS05740
uniprot id: E3H7X0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

572544:ILYOP RS09120
gene id: 572544:ILYOP_RS09120
uniprot id: E3H927
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

572544:ILYOP RS08980
gene id: 572544:ILYOP_RS08980
uniprot id: E3H8Z9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

572544:ILYOP RS00990
gene id: 572544:ILYOP_RS00990
uniprot id: E3H7L6
names: Similarity
messages: Belongs to the YicC/YloC family.

572544:ILYOP RS02985
gene id: 572544:ILYOP_RS02985
uniprot id: E3H6F2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

572544:ILYOP RS06000
gene id: 572544:ILYOP_RS06000
uniprot id: E3H8I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

572544:ILYOP RS00680
gene id: 572544:ILYOP_RS00680
uniprot id: E3H718
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

572544:ILYOP RS07980
gene id: 572544:ILYOP_RS07980
uniprot id: E3H8U8
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS11325
gene id: 572544:ILYOP_RS11325
uniprot id: E3HCK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS14275
gene id: 572544:ILYOP_RS14275
uniprot id: E3HD66
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572544:ILYOP RS12730
gene id: 572544:ILYOP_RS12730
uniprot id: E3HDR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

572544:ILYOP RS06105
gene id: 572544:ILYOP_RS06105
uniprot id: E3H8K9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

572544:ILYOP RS03420
gene id: 572544:ILYOP_RS03420
uniprot id: E3H6T4
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

572544:ILYOP RS07140
gene id: 572544:ILYOP_RS07140
uniprot id: E3HAL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

572544:ILYOP RS05320
gene id: 572544:ILYOP_RS05320
uniprot id: E3H7D8
names: Similarity
messages: Belongs to the HsdR family.

572544:ILYOP RS06230
gene id: 572544:ILYOP_RS06230
uniprot id: E3H8N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572544:ILYOP RS13390
gene id: 572544:ILYOP_RS13390
uniprot id: E3HCC0
names: Subcellular Location Annotation
messages: Membrane

572544:ILYOP RS09745
gene id: 572544:ILYOP_RS09745
uniprot id: E3HAE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

572544:ILYOP RS08495
gene id: 572544:ILYOP_RS08495
uniprot id: E3HA57
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

572544:ILYOP RS08960
gene id: 572544:ILYOP_RS08960
uniprot id: E3H8Z5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

572544:ILYOP RS05745
gene id: 572544:ILYOP_RS05745
uniprot id: E3H7X1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

572544:ILYOP RS14755
gene id: 572544:ILYOP_RS14755
uniprot id: E3HE13
names: Similarity
messages: Belongs to the MobA/MobL family.

572544:ILYOP RS03715
gene id: 572544:ILYOP_RS03715
uniprot id: E3H6Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

572544:ILYOP RS07970
gene id: 572544:ILYOP_RS07970
uniprot id: E3H8U6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.