572479:HPRAE RS04710
gene id: 572479:HPRAE_RS04710
uniprot id: E3DRM4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

572479:HPRAE RS06045
gene id: 572479:HPRAE_RS06045
uniprot id: E3DM36
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

572479:HPRAE RS05420
gene id: 572479:HPRAE_RS05420
uniprot id: E3DLF8
names: Similarity
messages: Belongs to the peptidase S58 family.

572479:HPRAE RS07360
gene id: 572479:HPRAE_RS07360
uniprot id: E3DNL6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

572479:HPRAE RS09175
gene id: 572479:HPRAE_RS09175
uniprot id: E3DQJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

572479:HPRAE RS05250
gene id: 572479:HPRAE_RS05250
uniprot id: E3DLC5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS10245
gene id: 572479:HPRAE_RS10245
uniprot id: E3DRQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

572479:HPRAE RS07530
gene id: 572479:HPRAE_RS07530
uniprot id: E3DNQ0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS09785
gene id: 572479:HPRAE_RS09785
uniprot id: E3DR42
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

572479:HPRAE RS10000
gene id: 572479:HPRAE_RS10000
uniprot id: E3DRE2
names: Similarity
messages: Belongs to the Skp family.

572479:HPRAE RS01980
gene id: 572479:HPRAE_RS01980
uniprot id: E3DNK9
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

572479:HPRAE RS07860
gene id: 572479:HPRAE_RS07860
uniprot id: E3DP31
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS06205
gene id: 572479:HPRAE_RS06205
uniprot id: E3DM67
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS01285
gene id: 572479:HPRAE_RS01285
uniprot id: E3DMT4
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS02220
gene id: 572479:HPRAE_RS02220
uniprot id: E3DNW9
names: Similarity
messages: Belongs to the ThiD family.

572479:HPRAE RS03355
gene id: 572479:HPRAE_RS03355
uniprot id: E3DQ61
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

572479:HPRAE RS08795
gene id: 572479:HPRAE_RS08795
uniprot id: E3DQ05
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS06415
gene id: 572479:HPRAE_RS06415
uniprot id: E3DMH8
names: Similarity
messages: Belongs to the transketolase family.

572479:HPRAE RS07565
gene id: 572479:HPRAE_RS07565
uniprot id: E3DNQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS06795
gene id: 572479:HPRAE_RS06795
uniprot id: E3DMX0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

572479:HPRAE RS01905
gene id: 572479:HPRAE_RS01905
uniprot id: E3DNJ4
names: Similarity
messages: Belongs to the peptidase M20A family.

572479:HPRAE RS06950
gene id: 572479:HPRAE_RS06950
uniprot id: E3DN01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

572479:HPRAE RS01300
gene id: 572479:HPRAE_RS01300
uniprot id: E3DMT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

572479:HPRAE RS05125
gene id: 572479:HPRAE_RS05125
uniprot id: E3DS24
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS08600
gene id: 572479:HPRAE_RS08600
uniprot id: E3DPX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

572479:HPRAE RS06280
gene id: 572479:HPRAE_RS06280
uniprot id: E3DMF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

572479:HPRAE RS10280
gene id: 572479:HPRAE_RS10280
uniprot id: E3DRR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

572479:HPRAE RS09450
gene id: 572479:HPRAE_RS09450
uniprot id: E3DQQ2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

572479:HPRAE RS04360
gene id: 572479:HPRAE_RS04360
uniprot id: E3DR89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

572479:HPRAE RS09210
gene id: 572479:HPRAE_RS09210
uniprot id: E3DQK3
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

572479:HPRAE RS06395
gene id: 572479:HPRAE_RS06395
uniprot id: E3DMH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

572479:HPRAE RS08180
gene id: 572479:HPRAE_RS08180
uniprot id: E3DPG7
names: Similarity
messages: Belongs to the ComB family.

572479:HPRAE RS03270
gene id: 572479:HPRAE_RS03270
uniprot id: E3DQ44
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

572479:HPRAE RS08605
gene id: 572479:HPRAE_RS08605
uniprot id: E3DPX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

572479:HPRAE RS03810
gene id: 572479:HPRAE_RS03810
uniprot id: E3DQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS01200
gene id: 572479:HPRAE_RS01200
uniprot id: E3DMR7
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS02690
gene id: 572479:HPRAE_RS02690
uniprot id: E3DPD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

572479:HPRAE RS03990
gene id: 572479:HPRAE_RS03990
uniprot id: E3DQV8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

572479:HPRAE RS03325
gene id: 572479:HPRAE_RS03325
uniprot id: E3DQ55
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS07935
gene id: 572479:HPRAE_RS07935
uniprot id: E3DP46
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

572479:HPRAE RS10295
gene id: 572479:HPRAE_RS10295
uniprot id: E3DRR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

572479:HPRAE RS08695
gene id: 572479:HPRAE_RS08695
uniprot id: E3DPY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

572479:HPRAE RS08405
gene id: 572479:HPRAE_RS08405
uniprot id: E3DPL1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

572479:HPRAE RS03815
gene id: 572479:HPRAE_RS03815
uniprot id: E3DQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

572479:HPRAE RS03540
gene id: 572479:HPRAE_RS03540
uniprot id: E3DQF2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

572479:HPRAE RS05820
gene id: 572479:HPRAE_RS05820
uniprot id: E3DLS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

572479:HPRAE RS04045
gene id: 572479:HPRAE_RS04045
uniprot id: E3DQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

572479:HPRAE RS06590
gene id: 572479:HPRAE_RS06590
uniprot id: E3DML3
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

572479:HPRAE RS02190
gene id: 572479:HPRAE_RS02190
uniprot id: E3DNW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

572479:HPRAE RS09420
gene id: 572479:HPRAE_RS09420
uniprot id: E3DQP6
names: Similarity
messages: Belongs to the UPF0178 family.

572479:HPRAE RS08360
gene id: 572479:HPRAE_RS08360
uniprot id: E3DPK1
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

572479:HPRAE RS06135
gene id: 572479:HPRAE_RS06135
uniprot id: E3DM53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

572479:HPRAE RS03020
gene id: 572479:HPRAE_RS03020
uniprot id: E3DPS7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

572479:HPRAE RS09960
gene id: 572479:HPRAE_RS09960
uniprot id: E3DRD4
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

572479:HPRAE RS09790
gene id: 572479:HPRAE_RS09790
uniprot id: E3DR43
names: Similarity
messages: Belongs to the RutC family.

572479:HPRAE RS03070
gene id: 572479:HPRAE_RS03070
uniprot id: E3DQ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

572479:HPRAE RS02815
gene id: 572479:HPRAE_RS02815
uniprot id: E3DPN6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

572479:HPRAE RS03040
gene id: 572479:HPRAE_RS03040
uniprot id: E3DPT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

572479:HPRAE RS01480
gene id: 572479:HPRAE_RS01480
uniprot id: E3DN40
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

572479:HPRAE RS07950
gene id: 572479:HPRAE_RS07950
uniprot id: E3DP49
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

572479:HPRAE RS06250
gene id: 572479:HPRAE_RS06250
uniprot id: E3DM76
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

572479:HPRAE RS02325
gene id: 572479:HPRAE_RS02325
uniprot id: E3DNZ0
names: Similarity
messages: Belongs to the peptidase C69 family.

572479:HPRAE RS02255
gene id: 572479:HPRAE_RS02255
uniprot id: E3DNX6
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS05445
gene id: 572479:HPRAE_RS05445
uniprot id: E3DLG3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

572479:HPRAE RS07180
gene id: 572479:HPRAE_RS07180
uniprot id: E3DNB2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS01875
gene id: 572479:HPRAE_RS01875
uniprot id: E3DNI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS01125
gene id: 572479:HPRAE_RS01125
uniprot id: E3DMQ2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

572479:HPRAE RS02835
gene id: 572479:HPRAE_RS02835
uniprot id: E3DPP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

572479:HPRAE RS10200
gene id: 572479:HPRAE_RS10200
uniprot id: E3DRQ0
names: Similarity
messages: Belongs to the peptidase M18 family.

572479:HPRAE RS08430
gene id: 572479:HPRAE_RS08430
uniprot id: E3DPT7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

572479:HPRAE RS04435
gene id: 572479:HPRAE_RS04435
uniprot id: E3DRA4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS01445
gene id: 572479:HPRAE_RS01445
uniprot id: E3DN33
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

572479:HPRAE RS10205
gene id: 572479:HPRAE_RS10205
uniprot id: E3DRQ1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS04645
gene id: 572479:HPRAE_RS04645
uniprot id: E3DRL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS02435
gene id: 572479:HPRAE_RS02435
uniprot id: E3DP84
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

572479:HPRAE RS06215
gene id: 572479:HPRAE_RS06215
uniprot id: E3DM69
names: Similarity
messages: Belongs to the FBPase class 3 family.

572479:HPRAE RS08490
gene id: 572479:HPRAE_RS08490
uniprot id: E3DPU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

572479:HPRAE RS06050
gene id: 572479:HPRAE_RS06050
uniprot id: E3DM37
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

572479:HPRAE RS10090
gene id: 572479:HPRAE_RS10090
uniprot id: E3DRG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

572479:HPRAE RS04915
gene id: 572479:HPRAE_RS04915
uniprot id: E3DRY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

572479:HPRAE RS06640
gene id: 572479:HPRAE_RS06640
uniprot id: E3DMU1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

572479:HPRAE RS01250
gene id: 572479:HPRAE_RS01250
uniprot id: E3DMS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS00465
gene id: 572479:HPRAE_RS00465
uniprot id: E3DLY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

572479:HPRAE RS09830
gene id: 572479:HPRAE_RS09830
uniprot id: E3DR51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

572479:HPRAE RS08010
gene id: 572479:HPRAE_RS08010
uniprot id: E3DP61
names: Similarity
messages: Belongs to the UPF0340 family.

572479:HPRAE RS08135
gene id: 572479:HPRAE_RS08135
uniprot id: E3DPF8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

572479:HPRAE RS01565
gene id: 572479:HPRAE_RS01565
uniprot id: E3DN58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS04775
gene id: 572479:HPRAE_RS04775
uniprot id: E3DRN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

572479:HPRAE RS02735
gene id: 572479:HPRAE_RS02735
uniprot id: E3DPM0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

572479:HPRAE RS02600
gene id: 572479:HPRAE_RS02600
uniprot id: E3DPB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

572479:HPRAE RS03185
gene id: 572479:HPRAE_RS03185
uniprot id: E3DQ29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

572479:HPRAE RS07730
gene id: 572479:HPRAE_RS07730
uniprot id: E3DP05
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

572479:HPRAE RS02380
gene id: 572479:HPRAE_RS02380
uniprot id: E3DP73
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS03530
gene id: 572479:HPRAE_RS03530
uniprot id: E3DQF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

572479:HPRAE RS08565
gene id: 572479:HPRAE_RS08565
uniprot id: E3DPW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

572479:HPRAE RS09070
gene id: 572479:HPRAE_RS09070
uniprot id: E3DQA9
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS07515
gene id: 572479:HPRAE_RS07515
uniprot id: E3DNP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

572479:HPRAE RS01430
gene id: 572479:HPRAE_RS01430
uniprot id: E3DN30
names: Subcellular Location Annotation
messages: Bacterial microcompartment

572479:HPRAE RS10780
gene id: 572479:HPRAE_RS10780
uniprot id: E3DS76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

572479:HPRAE RS04650
gene id: 572479:HPRAE_RS04650
uniprot id: E3DRL2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

572479:HPRAE RS00800
gene id: 572479:HPRAE_RS00800
uniprot id: E3DMB7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

572479:HPRAE RS03440
gene id: 572479:HPRAE_RS03440
uniprot id: E3DQD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

572479:HPRAE RS04760
gene id: 572479:HPRAE_RS04760
uniprot id: E3DRN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

572479:HPRAE RS00855
gene id: 572479:HPRAE_RS00855
uniprot id: E3DMC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

572479:HPRAE RS10870
gene id: 572479:HPRAE_RS10870
uniprot id: E3DPP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

572479:HPRAE RS03475
gene id: 572479:HPRAE_RS03475
uniprot id: E3DQD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS05230
gene id: 572479:HPRAE_RS05230
uniprot id: E3DLC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

572479:HPRAE RS00200
gene id: 572479:HPRAE_RS00200
uniprot id: E3DLL5
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS04800
gene id: 572479:HPRAE_RS04800
uniprot id: E3DRP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

572479:HPRAE RS10305
gene id: 572479:HPRAE_RS10305
uniprot id: E3DRS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

572479:HPRAE RS00435
gene id: 572479:HPRAE_RS00435
uniprot id: E3DLX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

572479:HPRAE RS01075
gene id: 572479:HPRAE_RS01075
uniprot id: E3DMP1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

572479:HPRAE RS06980
gene id: 572479:HPRAE_RS06980
uniprot id: E3DN77
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS02230
gene id: 572479:HPRAE_RS02230
uniprot id: E3DNX1
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

572479:HPRAE RS05310
gene id: 572479:HPRAE_RS05310
uniprot id: E3DLD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

572479:HPRAE RS00100
gene id: 572479:HPRAE_RS00100
uniprot id: E3DLJ5
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

572479:HPRAE RS08275
gene id: 572479:HPRAE_RS08275
uniprot id: E3DPI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

572479:HPRAE RS00815
gene id: 572479:HPRAE_RS00815
uniprot id: E3DMC0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

572479:HPRAE RS10235
gene id: 572479:HPRAE_RS10235
uniprot id: E3DRQ7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

572479:HPRAE RS09800
gene id: 572479:HPRAE_RS09800
uniprot id: E3DR45
names: Similarity
messages: Belongs to the peptidase S41A family.

572479:HPRAE RS02140
gene id: 572479:HPRAE_RS02140
uniprot id: E3DNV3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

572479:HPRAE RS02925
gene id: 572479:HPRAE_RS02925
uniprot id: E3DPQ8
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS02620
gene id: 572479:HPRAE_RS02620
uniprot id: E3DPC1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

572479:HPRAE RS03670
gene id: 572479:HPRAE_RS03670
uniprot id: E3DQH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

572479:HPRAE RS02990
gene id: 572479:HPRAE_RS02990
uniprot id: E3DPS1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

572479:HPRAE RS10110
gene id: 572479:HPRAE_RS10110
uniprot id: E3DRG4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

572479:HPRAE RS10070
gene id: 572479:HPRAE_RS10070
uniprot id: E3DRF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

572479:HPRAE RS07625
gene id: 572479:HPRAE_RS07625
uniprot id: E3DNR9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

572479:HPRAE RS07220
gene id: 572479:HPRAE_RS07220
uniprot id: E3DNC0
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS09215
gene id: 572479:HPRAE_RS09215
uniprot id: E3DQK4
names: Similarity
messages: Belongs to the EamA transporter family.

572479:HPRAE RS08415
gene id: 572479:HPRAE_RS08415
uniprot id: E3DPT4
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

572479:HPRAE RS07610
gene id: 572479:HPRAE_RS07610
uniprot id: E3DNR6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

572479:HPRAE RS03850
gene id: 572479:HPRAE_RS03850
uniprot id: E3DQT0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

572479:HPRAE RS03660
gene id: 572479:HPRAE_RS03660
uniprot id: E3DQH1
names: Similarity
messages: Belongs to the transpeptidase family.

572479:HPRAE RS00735
gene id: 572479:HPRAE_RS00735
uniprot id: E3DMA5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

572479:HPRAE RS04595
gene id: 572479:HPRAE_RS04595
uniprot id: E3DRK1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

572479:HPRAE RS03230
gene id: 572479:HPRAE_RS03230
uniprot id: E3DQ37
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

572479:HPRAE RS04345
gene id: 572479:HPRAE_RS04345
uniprot id: E3DR86
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS03975
gene id: 572479:HPRAE_RS03975
uniprot id: E3DQV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

572479:HPRAE RS07130
gene id: 572479:HPRAE_RS07130
uniprot id: E3DNA2
names: Similarity
messages: Belongs to the EamA transporter family.

572479:HPRAE RS03385
gene id: 572479:HPRAE_RS03385
uniprot id: E3DQ67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

572479:HPRAE RS02725
gene id: 572479:HPRAE_RS02725
uniprot id: E3DPL8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS07645
gene id: 572479:HPRAE_RS07645
uniprot id: E3DNS2
names: Subcellular Location Annotation
messages: Cytoplasm

572479:HPRAE RS09745
gene id: 572479:HPRAE_RS09745
uniprot id: E3DR34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS06290
gene id: 572479:HPRAE_RS06290
uniprot id: E3DMF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

572479:HPRAE RS09195
gene id: 572479:HPRAE_RS09195
uniprot id: E3DQK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

572479:HPRAE RS03870
gene id: 572479:HPRAE_RS03870
uniprot id: E3DQT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

572479:HPRAE RS04040
gene id: 572479:HPRAE_RS04040
uniprot id: E3DQW8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

572479:HPRAE RS06505
gene id: 572479:HPRAE_RS06505
uniprot id: E3DMJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

572479:HPRAE RS02580
gene id: 572479:HPRAE_RS02580
uniprot id: E3DPB3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

572479:HPRAE RS03785
gene id: 572479:HPRAE_RS03785
uniprot id: E3DQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

572479:HPRAE RS02545
gene id: 572479:HPRAE_RS02545
uniprot id: E3DPA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS00590
gene id: 572479:HPRAE_RS00590
uniprot id: E3DM10
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

572479:HPRAE RS04335
gene id: 572479:HPRAE_RS04335
uniprot id: E3DR84
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

572479:HPRAE RS05665
gene id: 572479:HPRAE_RS05665
uniprot id: E3DLP7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

572479:HPRAE RS07205
gene id: 572479:HPRAE_RS07205
uniprot id: E3DNB7
names: Similarity
messages: Belongs to the Dps family.

572479:HPRAE RS00210
gene id: 572479:HPRAE_RS00210
uniprot id: E3DLL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

572479:HPRAE RS10655
gene id: 572479:HPRAE_RS10655
uniprot id: E3DS51
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

572479:HPRAE RS04675
gene id: 572479:HPRAE_RS04675
uniprot id: E3DRL7
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

572479:HPRAE RS05610
gene id: 572479:HPRAE_RS05610
uniprot id: E3DLN6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

572479:HPRAE RS09720
gene id: 572479:HPRAE_RS09720
uniprot id: E3DR29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

572479:HPRAE RS04495
gene id: 572479:HPRAE_RS04495
uniprot id: E3DRI1
names: Similarity
messages: Belongs to the GSP E family.

572479:HPRAE RS03735
gene id: 572479:HPRAE_RS03735
uniprot id: E3DQI6
names: Subcellular Location Annotation
messages: Cytoplasm

572479:HPRAE RS01855
gene id: 572479:HPRAE_RS01855
uniprot id: E3DNI5
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

572479:HPRAE RS04790
gene id: 572479:HPRAE_RS04790
uniprot id: E3DRP0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

572479:HPRAE RS09940
gene id: 572479:HPRAE_RS09940
uniprot id: E3DRD0
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS09065
gene id: 572479:HPRAE_RS09065
uniprot id: E3DQA8
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS08585
gene id: 572479:HPRAE_RS08585
uniprot id: E3DPW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

572479:HPRAE RS00665
gene id: 572479:HPRAE_RS00665
uniprot id: E3DM91
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

572479:HPRAE RS01635
gene id: 572479:HPRAE_RS01635
uniprot id: E3DN71
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS10725
gene id: 572479:HPRAE_RS10725
uniprot id: E3DS65
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS09510
gene id: 572479:HPRAE_RS09510
uniprot id: E3DQR4
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

572479:HPRAE RS05360
gene id: 572479:HPRAE_RS05360
uniprot id: E3DLE7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS02105
gene id: 572479:HPRAE_RS02105
uniprot id: E3DNU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

572479:HPRAE RS06710
gene id: 572479:HPRAE_RS06710
uniprot id: E3DMV5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

572479:HPRAE RS05130
gene id: 572479:HPRAE_RS05130
uniprot id: E3DS25
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS05680
gene id: 572479:HPRAE_RS05680
uniprot id: E3DLQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

572479:HPRAE RS03155
gene id: 572479:HPRAE_RS03155
uniprot id: E3DQ23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

572479:HPRAE RS03845
gene id: 572479:HPRAE_RS03845
uniprot id: E3DQS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

572479:HPRAE RS03065
gene id: 572479:HPRAE_RS03065
uniprot id: E3DQ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

572479:HPRAE RS08375
gene id: 572479:HPRAE_RS08375
uniprot id: E3DPK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

572479:HPRAE RS08545
gene id: 572479:HPRAE_RS08545
uniprot id: E3DPW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

572479:HPRAE RS02645
gene id: 572479:HPRAE_RS02645
uniprot id: E3DPC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

572479:HPRAE RS00345
gene id: 572479:HPRAE_RS00345
uniprot id: E3DLW1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

572479:HPRAE RS01825
gene id: 572479:HPRAE_RS01825
uniprot id: E3DNH9
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

572479:HPRAE RS04310
gene id: 572479:HPRAE_RS04310
uniprot id: E3DR79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

572479:HPRAE RS10850
gene id: 572479:HPRAE_RS10850
uniprot id: E3DMR3
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS09555
gene id: 572479:HPRAE_RS09555
uniprot id: E3DQZ5
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS02215
gene id: 572479:HPRAE_RS02215
uniprot id: E3DNW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

572479:HPRAE RS09290
gene id: 572479:HPRAE_RS09290
uniprot id: E3DQM0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

572479:HPRAE RS07855
gene id: 572479:HPRAE_RS07855
uniprot id: E3DP30
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

572479:HPRAE RS10020
gene id: 572479:HPRAE_RS10020
uniprot id: E3DRE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS02205
gene id: 572479:HPRAE_RS02205
uniprot id: E3DNW6
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

572479:HPRAE RS08445
gene id: 572479:HPRAE_RS08445
uniprot id: E3DPU0
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS00490
gene id: 572479:HPRAE_RS00490
uniprot id: E3DLZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

572479:HPRAE RS01100
gene id: 572479:HPRAE_RS01100
uniprot id: E3DMP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS08520
gene id: 572479:HPRAE_RS08520
uniprot id: E3DPV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

572479:HPRAE RS03360
gene id: 572479:HPRAE_RS03360
uniprot id: E3DQ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

572479:HPRAE RS09645
gene id: 572479:HPRAE_RS09645
uniprot id: E3DR14
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

572479:HPRAE RS04815
gene id: 572479:HPRAE_RS04815
uniprot id: E3DRP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

572479:HPRAE RS01655
gene id: 572479:HPRAE_RS01655
uniprot id: E3DN75
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

572479:HPRAE RS09305
gene id: 572479:HPRAE_RS09305
uniprot id: E3DQM3
names: Similarity
messages: Belongs to the ParB family.

572479:HPRAE RS07775
gene id: 572479:HPRAE_RS07775
uniprot id: E3DP14
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

572479:HPRAE RS01270
gene id: 572479:HPRAE_RS01270
uniprot id: E3DMT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

572479:HPRAE RS04960
gene id: 572479:HPRAE_RS04960
uniprot id: E3DRZ1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

572479:HPRAE RS03400
gene id: 572479:HPRAE_RS03400
uniprot id: E3DQ70
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

572479:HPRAE RS01610
gene id: 572479:HPRAE_RS01610
uniprot id: E3DN67
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

572479:HPRAE RS05010
gene id: 572479:HPRAE_RS05010
uniprot id: E3DS01
names: Cofactor
messages: Binds 2 irons ions per subunit via 4 cysteine residues per iron.

572479:HPRAE RS10635
gene id: 572479:HPRAE_RS10635
uniprot id: E3DS47
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

572479:HPRAE RS07300
gene id: 572479:HPRAE_RS07300
uniprot id: E3DND6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS05585
gene id: 572479:HPRAE_RS05585
uniprot id: E3DLN1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

572479:HPRAE RS08465
gene id: 572479:HPRAE_RS08465
uniprot id: E3DPU4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

572479:HPRAE RS04970
gene id: 572479:HPRAE_RS04970
uniprot id: E3DRZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

572479:HPRAE RS08650
gene id: 572479:HPRAE_RS08650
uniprot id: E3DPY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

572479:HPRAE RS08805
gene id: 572479:HPRAE_RS08805
uniprot id: E3DQ07
names: Similarity
messages: Belongs to the BMP lipoprotein family.

572479:HPRAE RS05215
gene id: 572479:HPRAE_RS05215
uniprot id: E3DLB8
names: Similarity
messages: Belongs to the CinA family.

572479:HPRAE RS08255
gene id: 572479:HPRAE_RS08255
uniprot id: E3DPI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

572479:HPRAE RS03825
gene id: 572479:HPRAE_RS03825
uniprot id: E3DQS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

572479:HPRAE RS01605
gene id: 572479:HPRAE_RS01605
uniprot id: E3DN66
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

572479:HPRAE RS03635
gene id: 572479:HPRAE_RS03635
uniprot id: E3DQG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

572479:HPRAE RS10050
gene id: 572479:HPRAE_RS10050
uniprot id: E3DRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

572479:HPRAE RS01920
gene id: 572479:HPRAE_RS01920
uniprot id: E3DNJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

572479:HPRAE RS04980
gene id: 572479:HPRAE_RS04980
uniprot id: E3DRZ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

572479:HPRAE RS06350
gene id: 572479:HPRAE_RS06350
uniprot id: E3DMG5
names: Similarity
messages: Belongs to the UPF0758 family.

572479:HPRAE RS05315
gene id: 572479:HPRAE_RS05315
uniprot id: E3DLD8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

572479:HPRAE RS00225
gene id: 572479:HPRAE_RS00225
uniprot id: E3DLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS04835
gene id: 572479:HPRAE_RS04835
uniprot id: E3DRW6
names: Similarity
messages: Belongs to the DprA/Smf family.

572479:HPRAE RS04870
gene id: 572479:HPRAE_RS04870
uniprot id: E3DRX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

572479:HPRAE RS07575
gene id: 572479:HPRAE_RS07575
uniprot id: E3DNQ9
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

572479:HPRAE RS07920
gene id: 572479:HPRAE_RS07920
uniprot id: E3DM10
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

572479:HPRAE RS00910
gene id: 572479:HPRAE_RS00910
uniprot id: E3DME0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

572479:HPRAE RS04750
gene id: 572479:HPRAE_RS04750
uniprot id: E3DRN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

572479:HPRAE RS01130
gene id: 572479:HPRAE_RS01130
uniprot id: E3DMQ3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

572479:HPRAE RS06405
gene id: 572479:HPRAE_RS06405
uniprot id: E3DMH6
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

572479:HPRAE RS03830
gene id: 572479:HPRAE_RS03830
uniprot id: E3DQS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

572479:HPRAE RS06765
gene id: 572479:HPRAE_RS06765
uniprot id: E3DMW4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

572479:HPRAE RS10540
gene id: 572479:HPRAE_RS10540
uniprot id: E3DRW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS02490
gene id: 572479:HPRAE_RS02490
uniprot id: E3DP95
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

572479:HPRAE RS09360
gene id: 572479:HPRAE_RS09360
uniprot id: E3DQN4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

572479:HPRAE RS08480
gene id: 572479:HPRAE_RS08480
uniprot id: E3DPU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

572479:HPRAE RS10560
gene id: 572479:HPRAE_RS10560
uniprot id: E3DS32
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

572479:HPRAE RS06465
gene id: 572479:HPRAE_RS06465
uniprot id: E3DMI8
names: Similarity
messages: Belongs to the peptidase M16 family.

572479:HPRAE RS10775
gene id: 572479:HPRAE_RS10775
uniprot id: E3DS75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

572479:HPRAE RS08505
gene id: 572479:HPRAE_RS08505
uniprot id: E3DPV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

572479:HPRAE RS03180
gene id: 572479:HPRAE_RS03180
uniprot id: E3DQ28
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

572479:HPRAE RS08235
gene id: 572479:HPRAE_RS08235
uniprot id: E3DPH8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

572479:HPRAE RS04105
gene id: 572479:HPRAE_RS04105
uniprot id: E3DQY1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

572479:HPRAE RS07715
gene id: 572479:HPRAE_RS07715
uniprot id: E3DP02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

572479:HPRAE RS02485
gene id: 572479:HPRAE_RS02485
uniprot id: E3DP94
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

572479:HPRAE RS10565
gene id: 572479:HPRAE_RS10565
uniprot id: E3DS33
names: Subcellular Location Annotation
messages: cytosol

572479:HPRAE RS04010
gene id: 572479:HPRAE_RS04010
uniprot id: E3DQW2
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

572479:HPRAE RS03250
gene id: 572479:HPRAE_RS03250
uniprot id: E3DQ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

572479:HPRAE RS00270
gene id: 572479:HPRAE_RS00270
uniprot id: E3DLU8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

572479:HPRAE RS02780
gene id: 572479:HPRAE_RS02780
uniprot id: E3DPM9
names: Similarity
messages: Belongs to the FlgD family.

572479:HPRAE RS07290
gene id: 572479:HPRAE_RS07290
uniprot id: E3DND4
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS08115
gene id: 572479:HPRAE_RS08115
uniprot id: E3DPF4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

572479:HPRAE RS10545
gene id: 572479:HPRAE_RS10545
uniprot id: E3DS29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

572479:HPRAE RS00975
gene id: 572479:HPRAE_RS00975
uniprot id: E3DMM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

572479:HPRAE RS06380
gene id: 572479:HPRAE_RS06380
uniprot id: E3DMH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

572479:HPRAE RS09490
gene id: 572479:HPRAE_RS09490
uniprot id: E3DQR0
names: Similarity
messages: Belongs to the class-I fumarase family.

572479:HPRAE RS03300
gene id: 572479:HPRAE_RS03300
uniprot id: E3DQ50
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

572479:HPRAE RS00945
gene id: 572479:HPRAE_RS00945
uniprot id: E3DME7
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS01985
gene id: 572479:HPRAE_RS01985
uniprot id: E3DNL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

572479:HPRAE RS09235
gene id: 572479:HPRAE_RS09235
uniprot id: E3DQK8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

572479:HPRAE RS04035
gene id: 572479:HPRAE_RS04035
uniprot id: E3DQW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

572479:HPRAE RS09680
gene id: 572479:HPRAE_RS09680
uniprot id: E3DR21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

572479:HPRAE RS04900
gene id: 572479:HPRAE_RS04900
uniprot id: E3DRX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

572479:HPRAE RS00380
gene id: 572479:HPRAE_RS00380
uniprot id: E3DLW8
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS03025
gene id: 572479:HPRAE_RS03025
uniprot id: E3DPS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

572479:HPRAE RS00405
gene id: 572479:HPRAE_RS00405
uniprot id: E3DLX3
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

572479:HPRAE RS06195
gene id: 572479:HPRAE_RS06195
uniprot id: E3DM65
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.

572479:HPRAE RS03450
gene id: 572479:HPRAE_RS03450
uniprot id: E3DQD4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

572479:HPRAE RS01295
gene id: 572479:HPRAE_RS01295
uniprot id: E3DMT6
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

572479:HPRAE RS00690
gene id: 572479:HPRAE_RS00690
uniprot id: E3DM96
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

572479:HPRAE RS01320
gene id: 572479:HPRAE_RS01320
uniprot id: E3DN09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

572479:HPRAE RS06080
gene id: 572479:HPRAE_RS06080
uniprot id: E3DM43
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

572479:HPRAE RS08720
gene id: 572479:HPRAE_RS08720
uniprot id: E3DPZ4
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

572479:HPRAE RS09710
gene id: 572479:HPRAE_RS09710
uniprot id: E3DR27
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

572479:HPRAE RS08315
gene id: 572479:HPRAE_RS08315
uniprot id: E3DPJ2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

572479:HPRAE RS01210
gene id: 572479:HPRAE_RS01210
uniprot id: E3DMR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

572479:HPRAE RS03955
gene id: 572479:HPRAE_RS03955
uniprot id: E3DQV1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

572479:HPRAE RS02090
gene id: 572479:HPRAE_RS02090
uniprot id: E3DNU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

572479:HPRAE RS00675
gene id: 572479:HPRAE_RS00675
uniprot id: E3DM93
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

572479:HPRAE RS05070
gene id: 572479:HPRAE_RS05070
uniprot id: E3DS13
names: Similarity
messages: Belongs to the acylphosphatase family.

572479:HPRAE RS03725
gene id: 572479:HPRAE_RS03725
uniprot id: E3DQI4
names: Similarity
messages: Belongs to the YggT family.

572479:HPRAE RS07145
gene id: 572479:HPRAE_RS07145
uniprot id: E3DNA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

572479:HPRAE RS00610
gene id: 572479:HPRAE_RS00610
uniprot id: E3DM80
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

572479:HPRAE RS09040
gene id: 572479:HPRAE_RS09040
uniprot id: E3DQA3
names: Similarity
messages: Belongs to the glutamine synthetase family.

572479:HPRAE RS08775
gene id: 572479:HPRAE_RS08775
uniprot id: E3DQ01
names: Similarity
messages: Belongs to the UPF0047 family.

572479:HPRAE RS00585
gene id: 572479:HPRAE_RS00585
uniprot id: E3DM09
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

572479:HPRAE RS09640
gene id: 572479:HPRAE_RS09640
uniprot id: E3DR13
names: Similarity
messages: Belongs to the bacterial flagellin family.

572479:HPRAE RS02810
gene id: 572479:HPRAE_RS02810
uniprot id: E3DPN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

572479:HPRAE RS08660
gene id: 572479:HPRAE_RS08660
uniprot id: E3DPY2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

572479:HPRAE RS00635
gene id: 572479:HPRAE_RS00635
uniprot id: E3DM85
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

572479:HPRAE RS05915
gene id: 572479:HPRAE_RS05915
uniprot id: E3DM14
names: Similarity
messages: Belongs to the EamA transporter family.

572479:HPRAE RS07655
gene id: 572479:HPRAE_RS07655
uniprot id: E3DNS4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

572479:HPRAE RS10265
gene id: 572479:HPRAE_RS10265
uniprot id: E3DRR3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

572479:HPRAE RS00330
gene id: 572479:HPRAE_RS00330
uniprot id: E3DLV9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS09340
gene id: 572479:HPRAE_RS09340
uniprot id: E3DQN0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS02475
gene id: 572479:HPRAE_RS02475
uniprot id: E3DP92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

572479:HPRAE RS00595
gene id: 572479:HPRAE_RS00595
uniprot id: E3DM11
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

572479:HPRAE RS01890
gene id: 572479:HPRAE_RS01890
uniprot id: E3DNJ1
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

572479:HPRAE RS06160
gene id: 572479:HPRAE_RS06160
uniprot id: E3DM58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

572479:HPRAE RS04305
gene id: 572479:HPRAE_RS04305
uniprot id: E3DR78
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

572479:HPRAE RS07240
gene id: 572479:HPRAE_RS07240
uniprot id: E3DNC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

572479:HPRAE RS01060
gene id: 572479:HPRAE_RS01060
uniprot id: E3DMN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

572479:HPRAE RS04700
gene id: 572479:HPRAE_RS04700
uniprot id: E3DRM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

572479:HPRAE RS07175
gene id: 572479:HPRAE_RS07175
uniprot id: E3DNB1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS02405
gene id: 572479:HPRAE_RS02405
uniprot id: E3DP78
names: Cofactor
messages: Binds 1 zinc ion per subunit.

572479:HPRAE RS00780
gene id: 572479:HPRAE_RS00780
uniprot id: E3DMB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

572479:HPRAE RS01425
gene id: 572479:HPRAE_RS01425
uniprot id: E3DN29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

572479:HPRAE RS03685
gene id: 572479:HPRAE_RS03685
uniprot id: E3DQH6
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS00725
gene id: 572479:HPRAE_RS00725
uniprot id: E3DMA3
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS10130
gene id: 572479:HPRAE_RS10130
uniprot id: E3DRG8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

572479:HPRAE RS01945
gene id: 572479:HPRAE_RS01945
uniprot id: E3DNK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS09525
gene id: 572479:HPRAE_RS09525
uniprot id: E3DQY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

572479:HPRAE RS08985
gene id: 572479:HPRAE_RS08985
uniprot id: E3DQ92
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

572479:HPRAE RS04740
gene id: 572479:HPRAE_RS04740
uniprot id: E3DRN0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

572479:HPRAE RS10805
gene id: 572479:HPRAE_RS10805
uniprot id: E3DS81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

572479:HPRAE RS04615
gene id: 572479:HPRAE_RS04615
uniprot id: E3DRK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

572479:HPRAE RS03645
gene id: 572479:HPRAE_RS03645
uniprot id: E3DQG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

572479:HPRAE RS00180
gene id: 572479:HPRAE_RS00180
uniprot id: E3DLL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

572479:HPRAE RS10335
gene id: 572479:HPRAE_RS10335
uniprot id: E3DRS7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

572479:HPRAE RS04810
gene id: 572479:HPRAE_RS04810
uniprot id: E3DRP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

572479:HPRAE RS08575
gene id: 572479:HPRAE_RS08575
uniprot id: E3DPW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

572479:HPRAE RS08735
gene id: 572479:HPRAE_RS08735
uniprot id: E3DPZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

572479:HPRAE RS06240
gene id: 572479:HPRAE_RS06240
uniprot id: E3DM74
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

572479:HPRAE RS08290
gene id: 572479:HPRAE_RS08290
uniprot id: E3DPI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

572479:HPRAE RS07520
gene id: 572479:HPRAE_RS07520
uniprot id: E3DNP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

572479:HPRAE RS03705
gene id: 572479:HPRAE_RS03705
uniprot id: E3DQI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

572479:HPRAE RS02075
gene id: 572479:HPRAE_RS02075
uniprot id: E3DNU0
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

572479:HPRAE RS10700
gene id: 572479:HPRAE_RS10700
uniprot id: E3DS60
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS05785
gene id: 572479:HPRAE_RS05785
uniprot id: E3DLS2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

572479:HPRAE RS09380
gene id: 572479:HPRAE_RS09380
uniprot id: E3DQN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

572479:HPRAE RS01790
gene id: 572479:HPRAE_RS01790
uniprot id: E3DNH1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

572479:HPRAE RS07970
gene id: 572479:HPRAE_RS07970
uniprot id: E3DP53
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS03555
gene id: 572479:HPRAE_RS03555
uniprot id: E3DQF5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

572479:HPRAE RS04860
gene id: 572479:HPRAE_RS04860
uniprot id: E3DRX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

572479:HPRAE RS00545
gene id: 572479:HPRAE_RS00545
uniprot id: E3DM01
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS04555
gene id: 572479:HPRAE_RS04555
uniprot id: E3DRJ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

572479:HPRAE RS04275
gene id: 572479:HPRAE_RS04275
uniprot id: E3DR72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

572479:HPRAE RS06440
gene id: 572479:HPRAE_RS06440
uniprot id: E3DMI3
names: Similarity
messages: Belongs to the fabD family.

572479:HPRAE RS08725
gene id: 572479:HPRAE_RS08725
uniprot id: E3DPZ5
names: Similarity
messages: Belongs to the ycf81 family.

572479:HPRAE RS06180
gene id: 572479:HPRAE_RS06180
uniprot id: E3DM62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS07750
gene id: 572479:HPRAE_RS07750
uniprot id: E3DP09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

572479:HPRAE RS00820
gene id: 572479:HPRAE_RS00820
uniprot id: E3DMC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

572479:HPRAE RS05005
gene id: 572479:HPRAE_RS05005
uniprot id: E3DS00
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

572479:HPRAE RS04670
gene id: 572479:HPRAE_RS04670
uniprot id: E3DRL6
names: Similarity
messages: Belongs to the peptidase M29 family.

572479:HPRAE RS02515
gene id: 572479:HPRAE_RS02515
uniprot id: E3DPA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

572479:HPRAE RS00240
gene id: 572479:HPRAE_RS00240
uniprot id: E3DLM3
names: Similarity
messages: Belongs to the UPF0246 family.

572479:HPRAE RS08130
gene id: 572479:HPRAE_RS08130
uniprot id: E3DPF7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS09095
gene id: 572479:HPRAE_RS09095
uniprot id: E3DQB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

572479:HPRAE RS05640
gene id: 572479:HPRAE_RS05640
uniprot id: E3DLP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS08745
gene id: 572479:HPRAE_RS08745
uniprot id: E3DPZ9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

572479:HPRAE RS05205
gene id: 572479:HPRAE_RS05205
uniprot id: E3DLB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

572479:HPRAE RS05165
gene id: 572479:HPRAE_RS05165
uniprot id: E3DS28
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

572479:HPRAE RS02120
gene id: 572479:HPRAE_RS02120
uniprot id: E3DNU9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

572479:HPRAE RS00115
gene id: 572479:HPRAE_RS00115
uniprot id: E3DLJ8
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

572479:HPRAE RS06420
gene id: 572479:HPRAE_RS06420
uniprot id: E3DMH9
names: Similarity
messages: Belongs to the EamA transporter family.

572479:HPRAE RS04450
gene id: 572479:HPRAE_RS04450
uniprot id: E3DRA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS10595
gene id: 572479:HPRAE_RS10595
uniprot id: E3DS39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS05705
gene id: 572479:HPRAE_RS05705
uniprot id: E3DLQ5
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

572479:HPRAE RS01050
gene id: 572479:HPRAE_RS01050
uniprot id: E3DMN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS04550
gene id: 572479:HPRAE_RS04550
uniprot id: E3DRJ2
names: Similarity
messages: Belongs to the bacterial secretin family.

572479:HPRAE RS05720
gene id: 572479:HPRAE_RS05720
uniprot id: E3DLQ8
names: Similarity
messages: Belongs to the peptidase C1 family.

572479:HPRAE RS04350
gene id: 572479:HPRAE_RS04350
uniprot id: E3DR87
names: Similarity
messages: Belongs to the GSP E family.

572479:HPRAE RS07800
gene id: 572479:HPRAE_RS07800
uniprot id: E3DP19
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS03780
gene id: 572479:HPRAE_RS03780
uniprot id: E3DQR6
names: Similarity
messages: Belongs to the RemA family.

572479:HPRAE RS03865
gene id: 572479:HPRAE_RS03865
uniprot id: E3DQT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

572479:HPRAE RS03010
gene id: 572479:HPRAE_RS03010
uniprot id: E3DPS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

572479:HPRAE RS03615
gene id: 572479:HPRAE_RS03615
uniprot id: E3DQG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

572479:HPRAE RS04025
gene id: 572479:HPRAE_RS04025
uniprot id: E3DQW5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

572479:HPRAE RS10795
gene id: 572479:HPRAE_RS10795
uniprot id: E3DS79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

572479:HPRAE RS05405
gene id: 572479:HPRAE_RS05405
uniprot id: E3DLF6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

572479:HPRAE RS09000
gene id: 572479:HPRAE_RS09000
uniprot id: E3DQ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

572479:HPRAE RS08570
gene id: 572479:HPRAE_RS08570
uniprot id: E3DPW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

572479:HPRAE RS07650
gene id: 572479:HPRAE_RS07650
uniprot id: E3DNS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

572479:HPRAE RS07875
gene id: 572479:HPRAE_RS07875
uniprot id: E3DP34
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

572479:HPRAE RS06320
gene id: 572479:HPRAE_RS06320
uniprot id: E3DMF9
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

572479:HPRAE RS06455
gene id: 572479:HPRAE_RS06455
uniprot id: E3DMI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

572479:HPRAE RS02635
gene id: 572479:HPRAE_RS02635
uniprot id: E3DPC4
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS08450
gene id: 572479:HPRAE_RS08450
uniprot id: E3DPU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

572479:HPRAE RS08580
gene id: 572479:HPRAE_RS08580
uniprot id: E3DPW7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

572479:HPRAE RS02965
gene id: 572479:HPRAE_RS02965
uniprot id: E3DPR6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

572479:HPRAE RS00320
gene id: 572479:HPRAE_RS00320
uniprot id: E3DLV7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS06650
gene id: 572479:HPRAE_RS06650
uniprot id: E3DMU3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

572479:HPRAE RS09910
gene id: 572479:HPRAE_RS09910
uniprot id: E3DRC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

572479:HPRAE RS00125
gene id: 572479:HPRAE_RS00125
uniprot id: E3DLK0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

572479:HPRAE RS07155
gene id: 572479:HPRAE_RS07155
uniprot id: E3DNA7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS10770
gene id: 572479:HPRAE_RS10770
uniprot id: E3DS74
names: Similarity
messages: Belongs to the ParB family.

572479:HPRAE RS04030
gene id: 572479:HPRAE_RS04030
uniprot id: E3DQW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

572479:HPRAE RS05105
gene id: 572479:HPRAE_RS05105
uniprot id: E3DS20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

572479:HPRAE RS10665
gene id: 572479:HPRAE_RS10665
uniprot id: E3DS53
names: Similarity
messages: Belongs to the GARS family.

572479:HPRAE RS07490
gene id: 572479:HPRAE_RS07490
uniprot id: E3DNP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS03225
gene id: 572479:HPRAE_RS03225
uniprot id: E3DQ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

572479:HPRAE RS07585
gene id: 572479:HPRAE_RS07585
uniprot id: E3DNR1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS06600
gene id: 572479:HPRAE_RS06600
uniprot id: E3DML5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

572479:HPRAE RS04120
gene id: 572479:HPRAE_RS04120
uniprot id: E3DQY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

572479:HPRAE RS01455
gene id: 572479:HPRAE_RS01455
uniprot id: E3DN35
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

572479:HPRAE RS08595
gene id: 572479:HPRAE_RS08595
uniprot id: E3DPX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

572479:HPRAE RS04015
gene id: 572479:HPRAE_RS04015
uniprot id: E3DQW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

572479:HPRAE RS07230
gene id: 572479:HPRAE_RS07230
uniprot id: E3DNC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

572479:HPRAE RS01345
gene id: 572479:HPRAE_RS01345
uniprot id: E3DN14
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS06880
gene id: 572479:HPRAE_RS06880
uniprot id: E3DMY8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

572479:HPRAE RS06425
gene id: 572479:HPRAE_RS06425
uniprot id: E3DMI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

572479:HPRAE RS07580
gene id: 572479:HPRAE_RS07580
uniprot id: E3DNR0
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

572479:HPRAE RS03675
gene id: 572479:HPRAE_RS03675
uniprot id: E3DQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS07945
gene id: 572479:HPRAE_RS07945
uniprot id: E3DP48
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS02945
gene id: 572479:HPRAE_RS02945
uniprot id: E3DPR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS06975
gene id: 572479:HPRAE_RS06975
uniprot id: E3DN76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

572479:HPRAE RS10640
gene id: 572479:HPRAE_RS10640
uniprot id: E3DS48
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS05580
gene id: 572479:HPRAE_RS05580
uniprot id: E3DLN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

572479:HPRAE RS02315
gene id: 572479:HPRAE_RS02315
uniprot id: E3DNY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS01310
gene id: 572479:HPRAE_RS01310
uniprot id: E3DN07
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

572479:HPRAE RS04570
gene id: 572479:HPRAE_RS04570
uniprot id: E3DRJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

572479:HPRAE RS09365
gene id: 572479:HPRAE_RS09365
uniprot id: E3DQN5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

572479:HPRAE RS08125
gene id: 572479:HPRAE_RS08125
uniprot id: E3DPF6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

572479:HPRAE RS00845
gene id: 572479:HPRAE_RS00845
uniprot id: E3DMC6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

572479:HPRAE RS04695
gene id: 572479:HPRAE_RS04695
uniprot id: E3DRM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS03465
gene id: 572479:HPRAE_RS03465
uniprot id: E3DQD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

572479:HPRAE RS04085
gene id: 572479:HPRAE_RS04085
uniprot id: E3DQX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

572479:HPRAE RS06385
gene id: 572479:HPRAE_RS06385
uniprot id: E3DMH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

572479:HPRAE RS01155
gene id: 572479:HPRAE_RS01155
uniprot id: E3DMQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

572479:HPRAE RS00755
gene id: 572479:HPRAE_RS00755
uniprot id: E3DMA9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

572479:HPRAE RS04770
gene id: 572479:HPRAE_RS04770
uniprot id: E3DRN6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

572479:HPRAE RS01240
gene id: 572479:HPRAE_RS01240
uniprot id: E3DMS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS08380
gene id: 572479:HPRAE_RS08380
uniprot id: E3DPK6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS07460
gene id: 572479:HPRAE_RS07460
uniprot id: E3DNN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS07685
gene id: 572479:HPRAE_RS07685
uniprot id: E3DNZ6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

572479:HPRAE RS01160
gene id: 572479:HPRAE_RS01160
uniprot id: E3DMQ9
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS00020
gene id: 572479:HPRAE_RS00020
uniprot id: E3DLI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

572479:HPRAE RS02130
gene id: 572479:HPRAE_RS02130
uniprot id: E3DNV1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

572479:HPRAE RS06170
gene id: 572479:HPRAE_RS06170
uniprot id: E3DM60
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

572479:HPRAE RS00395
gene id: 572479:HPRAE_RS00395
uniprot id: E3DLX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

572479:HPRAE RS06870
gene id: 572479:HPRAE_RS06870
uniprot id: E3DMY6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

572479:HPRAE RS04295
gene id: 572479:HPRAE_RS04295
uniprot id: E3DR76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

572479:HPRAE RS01615
gene id: 572479:HPRAE_RS01615
uniprot id: E3DN68
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

572479:HPRAE RS00785
gene id: 572479:HPRAE_RS00785
uniprot id: E3DMB4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

572479:HPRAE RS08645
gene id: 572479:HPRAE_RS08645
uniprot id: E3DPX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

572479:HPRAE RS04600
gene id: 572479:HPRAE_RS04600
uniprot id: E3DRK2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

572479:HPRAE RS07795
gene id: 572479:HPRAE_RS07795
uniprot id: E3DP18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS03280
gene id: 572479:HPRAE_RS03280
uniprot id: E3DQ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

572479:HPRAE RS07250
gene id: 572479:HPRAE_RS07250
uniprot id: E3DNC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

572479:HPRAE RS01510
gene id: 572479:HPRAE_RS01510
uniprot id: E3DN46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS08485
gene id: 572479:HPRAE_RS08485
uniprot id: E3DPU8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

572479:HPRAE RS05660
gene id: 572479:HPRAE_RS05660
uniprot id: E3DLP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

572479:HPRAE RS04270
gene id: 572479:HPRAE_RS04270
uniprot id: E3DR71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

572479:HPRAE RS00655
gene id: 572479:HPRAE_RS00655
uniprot id: E3DM89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS04655
gene id: 572479:HPRAE_RS04655
uniprot id: E3DRL3
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS00010
gene id: 572479:HPRAE_RS00010
uniprot id: E3DLI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

572479:HPRAE RS08555
gene id: 572479:HPRAE_RS08555
uniprot id: E3DPW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

572479:HPRAE RS02080
gene id: 572479:HPRAE_RS02080
uniprot id: E3DNU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

572479:HPRAE RS09580
gene id: 572479:HPRAE_RS09580
uniprot id: E3DR00
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

572479:HPRAE RS03805
gene id: 572479:HPRAE_RS03805
uniprot id: E3DQS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS09730
gene id: 572479:HPRAE_RS09730
uniprot id: E3DR31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

572479:HPRAE RS08470
gene id: 572479:HPRAE_RS08470
uniprot id: E3DPU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

572479:HPRAE RS10175
gene id: 572479:HPRAE_RS10175
uniprot id: E3DRH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

572479:HPRAE RS09080
gene id: 572479:HPRAE_RS09080
uniprot id: E3DQB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

572479:HPRAE RS07880
gene id: 572479:HPRAE_RS07880
uniprot id: E3DP35
names: Similarity
messages: Belongs to the sigma-54 factor family.

572479:HPRAE RS03750
gene id: 572479:HPRAE_RS03750
uniprot id: E3DQI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

572479:HPRAE RS01390
gene id: 572479:HPRAE_RS01390
uniprot id: E3DN22
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

572479:HPRAE RS02100
gene id: 572479:HPRAE_RS02100
uniprot id: E3DNU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

572479:HPRAE RS08390
gene id: 572479:HPRAE_RS08390
uniprot id: E3DPK8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

572479:HPRAE RS02390
gene id: 572479:HPRAE_RS02390
uniprot id: E3DP75
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

572479:HPRAE RS06075
gene id: 572479:HPRAE_RS06075
uniprot id: E3DM42
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

572479:HPRAE RS06820
gene id: 572479:HPRAE_RS06820
uniprot id: E3DMX5
names: Similarity
messages: Belongs to the Ahb/Nir family.

572479:HPRAE RS00740
gene id: 572479:HPRAE_RS00740
uniprot id: E3DMA6
names: Similarity
messages: Belongs to the thioredoxin family.

572479:HPRAE RS02840
gene id: 572479:HPRAE_RS02840
uniprot id: E3DPP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

572479:HPRAE RS10720
gene id: 572479:HPRAE_RS10720
uniprot id: E3DS64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

572479:HPRAE RS01085
gene id: 572479:HPRAE_RS01085
uniprot id: E3DMP3
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

572479:HPRAE RS09455
gene id: 572479:HPRAE_RS09455
uniprot id: E3DQQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

572479:HPRAE RS08395
gene id: 572479:HPRAE_RS08395
uniprot id: E3DPK9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

572479:HPRAE RS07150
gene id: 572479:HPRAE_RS07150
uniprot id: E3DNA6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

572479:HPRAE RS03305
gene id: 572479:HPRAE_RS03305
uniprot id: E3DQ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

572479:HPRAE RS10010
gene id: 572479:HPRAE_RS10010
uniprot id: E3DRE4
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS10060
gene id: 572479:HPRAE_RS10060
uniprot id: E3DRF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

572479:HPRAE RS03455
gene id: 572479:HPRAE_RS03455
uniprot id: E3DQD5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

572479:HPRAE RS02765
gene id: 572479:HPRAE_RS02765
uniprot id: E3DPM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS11235
gene id: 572479:HPRAE_RS11235
uniprot id: E3DNB9
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

572479:HPRAE RS09770
gene id: 572479:HPRAE_RS09770
uniprot id: E3DR39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

572479:HPRAE RS09090
gene id: 572479:HPRAE_RS09090
uniprot id: E3DQB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS03790
gene id: 572479:HPRAE_RS03790
uniprot id: E3DQR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

572479:HPRAE RS03110
gene id: 572479:HPRAE_RS03110
uniprot id: E3DQ19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

572479:HPRAE RS01495
gene id: 572479:HPRAE_RS01495
uniprot id: E3DN43
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

572479:HPRAE RS04115
gene id: 572479:HPRAE_RS04115
uniprot id: E3DQY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

572479:HPRAE RS03480
gene id: 572479:HPRAE_RS03480
uniprot id: E3DQE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

572479:HPRAE RS09010
gene id: 572479:HPRAE_RS09010
uniprot id: E3DQ97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

572479:HPRAE RS01095
gene id: 572479:HPRAE_RS01095
uniprot id: E3DMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS03620
gene id: 572479:HPRAE_RS03620
uniprot id: E3DQG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

572479:HPRAE RS05290
gene id: 572479:HPRAE_RS05290
uniprot id: E3DLD3
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

572479:HPRAE RS08790
gene id: 572479:HPRAE_RS08790
uniprot id: E3DQ04
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

572479:HPRAE RS08060
gene id: 572479:HPRAE_RS08060
uniprot id: E3DPE3
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

572479:HPRAE RS04560
gene id: 572479:HPRAE_RS04560
uniprot id: E3DRJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

572479:HPRAE RS09375
gene id: 572479:HPRAE_RS09375
uniprot id: E3DQN7
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS09190
gene id: 572479:HPRAE_RS09190
uniprot id: E3DQJ9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

572479:HPRAE RS02565
gene id: 572479:HPRAE_RS02565
uniprot id: E3DPB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

572479:HPRAE RS05270
gene id: 572479:HPRAE_RS05270
uniprot id: E3DLC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

572479:HPRAE RS03375
gene id: 572479:HPRAE_RS03375
uniprot id: E3DQ65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

572479:HPRAE RS03820
gene id: 572479:HPRAE_RS03820
uniprot id: E3DQS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

572479:HPRAE RS07540
gene id: 572479:HPRAE_RS07540
uniprot id: E3DNQ2
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

572479:HPRAE RS09980
gene id: 572479:HPRAE_RS09980
uniprot id: E3DRD8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

572479:HPRAE RS05015
gene id: 572479:HPRAE_RS05015
uniprot id: E3DS02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

572479:HPRAE RS05345
gene id: 572479:HPRAE_RS05345
uniprot id: E3DLE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

572479:HPRAE RS03665
gene id: 572479:HPRAE_RS03665
uniprot id: E3DQH2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS06500
gene id: 572479:HPRAE_RS06500
uniprot id: E3DMJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS00950
gene id: 572479:HPRAE_RS00950
uniprot id: E3DME8
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS04935
gene id: 572479:HPRAE_RS04935
uniprot id: E3DRY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

572479:HPRAE RS01055
gene id: 572479:HPRAE_RS01055
uniprot id: E3DMN7
names: Similarity
messages: Belongs to the threonine aldolase family.

572479:HPRAE RS08750
gene id: 572479:HPRAE_RS08750
uniprot id: E3DQ00
names: Similarity
messages: Belongs to the CtsR family.

572479:HPRAE RS08200
gene id: 572479:HPRAE_RS08200
uniprot id: E3DPH1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

572479:HPRAE RS06565
gene id: 572479:HPRAE_RS06565
uniprot id: E3DMK8
names: Similarity
messages: Belongs to the hemerythrin family.

572479:HPRAE RS00810
gene id: 572479:HPRAE_RS00810
uniprot id: E3DMB9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

572479:HPRAE RS09395
gene id: 572479:HPRAE_RS09395
uniprot id: E3DQP1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

572479:HPRAE RS02830
gene id: 572479:HPRAE_RS02830
uniprot id: E3DPN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

572479:HPRAE RS08530
gene id: 572479:HPRAE_RS08530
uniprot id: E3DPV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

572479:HPRAE RS10690
gene id: 572479:HPRAE_RS10690
uniprot id: E3DS58
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

572479:HPRAE RS01280
gene id: 572479:HPRAE_RS01280
uniprot id: E3DMT3
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

572479:HPRAE RS05335
gene id: 572479:HPRAE_RS05335
uniprot id: E3DLE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

572479:HPRAE RS10155
gene id: 572479:HPRAE_RS10155
uniprot id: E3DRH3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

572479:HPRAE RS10740
gene id: 572479:HPRAE_RS10740
uniprot id: E3DS68
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

572479:HPRAE RS02350
gene id: 572479:HPRAE_RS02350
uniprot id: E3DP67
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS08440
gene id: 572479:HPRAE_RS08440
uniprot id: E3DPT9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS03260
gene id: 572479:HPRAE_RS03260
uniprot id: E3DQ42
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS00475
gene id: 572479:HPRAE_RS00475
uniprot id: E3DLY7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS08170
gene id: 572479:HPRAE_RS08170
uniprot id: E3DPG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

572479:HPRAE RS10790
gene id: 572479:HPRAE_RS10790
uniprot id: E3DS78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

572479:HPRAE RS08120
gene id: 572479:HPRAE_RS08120
uniprot id: E3DPF5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

572479:HPRAE RS03220
gene id: 572479:HPRAE_RS03220
uniprot id: E3DQ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

572479:HPRAE RS06445
gene id: 572479:HPRAE_RS06445
uniprot id: E3DMI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

572479:HPRAE RS08635
gene id: 572479:HPRAE_RS08635
uniprot id: E3DPX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

572479:HPRAE RS00890
gene id: 572479:HPRAE_RS00890
uniprot id: E3DMD6
names: Similarity
messages: Belongs to the UPF0751 family.

572479:HPRAE RS04625
gene id: 572479:HPRAE_RS04625
uniprot id: E3DRK7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

572479:HPRAE RS00410
gene id: 572479:HPRAE_RS00410
uniprot id: E3DLX4
names: Similarity
messages: Belongs to the RutC family.

572479:HPRAE RS05730
gene id: 572479:HPRAE_RS05730
uniprot id: E3DLR0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

572479:HPRAE RS06865
gene id: 572479:HPRAE_RS06865
uniprot id: E3DMY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

572479:HPRAE RS07535
gene id: 572479:HPRAE_RS07535
uniprot id: E3DNQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

572479:HPRAE RS04855
gene id: 572479:HPRAE_RS04855
uniprot id: E3DRX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

572479:HPRAE RS05400
gene id: 572479:HPRAE_RS05400
uniprot id: E3DLF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS02745
gene id: 572479:HPRAE_RS02745
uniprot id: E3DPM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

572479:HPRAE RS10450
gene id: 572479:HPRAE_RS10450
uniprot id: E3DRU5
names: Similarity
messages: Belongs to the HsdR family.

572479:HPRAE RS08820
gene id: 572479:HPRAE_RS08820
uniprot id: E3DQ75
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

572479:HPRAE RS02685
gene id: 572479:HPRAE_RS02685
uniprot id: E3DPD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

572479:HPRAE RS01775
gene id: 572479:HPRAE_RS01775
uniprot id: E3DNG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

572479:HPRAE RS00135
gene id: 572479:HPRAE_RS00135
uniprot id: E3DLK2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS08700
gene id: 572479:HPRAE_RS08700
uniprot id: E3DPZ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

572479:HPRAE RS04890
gene id: 572479:HPRAE_RS04890
uniprot id: E3DRX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

572479:HPRAE RS07410
gene id: 572479:HPRAE_RS07410
uniprot id: E3DNM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

572479:HPRAE RS09780
gene id: 572479:HPRAE_RS09780
uniprot id: E3DR41
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS00790
gene id: 572479:HPRAE_RS00790
uniprot id: E3DMB5
names: Similarity
messages: Belongs to the GARS family.

572479:HPRAE RS06850
gene id: 572479:HPRAE_RS06850
uniprot id: E3DMY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

572479:HPRAE RS07355
gene id: 572479:HPRAE_RS07355
uniprot id: E3DNL5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

572479:HPRAE RS09245
gene id: 572479:HPRAE_RS09245
uniprot id: E3DQL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

572479:HPRAE RS09200
gene id: 572479:HPRAE_RS09200
uniprot id: E3DQK1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

572479:HPRAE RS04780
gene id: 572479:HPRAE_RS04780
uniprot id: E3DRN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

572479:HPRAE RS01810
gene id: 572479:HPRAE_RS01810
uniprot id: E3DNH6
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS04420
gene id: 572479:HPRAE_RS04420
uniprot id: E3DRA1
names: Similarity
messages: Belongs to the bacterial secretin family.

572479:HPRAE RS10575
gene id: 572479:HPRAE_RS10575
uniprot id: E3DS35
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

572479:HPRAE RS10150
gene id: 572479:HPRAE_RS10150
uniprot id: E3DRH2
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS00005
gene id: 572479:HPRAE_RS00005
uniprot id: E3DLI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

572479:HPRAE RS08040
gene id: 572479:HPRAE_RS08040
uniprot id: E3DPD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS04910
gene id: 572479:HPRAE_RS04910
uniprot id: E3DRY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

572479:HPRAE RS04220
gene id: 572479:HPRAE_RS04220
uniprot id: E3DR61
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS04880
gene id: 572479:HPRAE_RS04880
uniprot id: E3DRX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

572479:HPRAE RS08845
gene id: 572479:HPRAE_RS08845
uniprot id: E3DQ80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

572479:HPRAE RS03970
gene id: 572479:HPRAE_RS03970
uniprot id: E3DQV4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

572479:HPRAE RS10225
gene id: 572479:HPRAE_RS10225
uniprot id: E3DRQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

572479:HPRAE RS01230
gene id: 572479:HPRAE_RS01230
uniprot id: E3DMS3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

572479:HPRAE RS10760
gene id: 572479:HPRAE_RS10760
uniprot id: E3DS72
names: Similarity
messages: Belongs to the ParB family.

572479:HPRAE RS06230
gene id: 572479:HPRAE_RS06230
uniprot id: E3DM72
names: Similarity
messages: Belongs to the phosphohexose mutase family.

572479:HPRAE RS10120
gene id: 572479:HPRAE_RS10120
uniprot id: E3DRG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

572479:HPRAE RS10035
gene id: 572479:HPRAE_RS10035
uniprot id: E3DRE9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

572479:HPRAE RS06325
gene id: 572479:HPRAE_RS06325
uniprot id: E3DMG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

572479:HPRAE RS01835
gene id: 572479:HPRAE_RS01835
uniprot id: E3DNI1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

572479:HPRAE RS03960
gene id: 572479:HPRAE_RS03960
uniprot id: E3DQV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

572479:HPRAE RS03890
gene id: 572479:HPRAE_RS03890
uniprot id: E3DQT8
names: Similarity
messages: Belongs to the asp23 family.

572479:HPRAE RS08095
gene id: 572479:HPRAE_RS08095
uniprot id: E3DPF0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

572479:HPRAE RS08045
gene id: 572479:HPRAE_RS08045
uniprot id: E3DPD9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

572479:HPRAE RS03900
gene id: 572479:HPRAE_RS03900
uniprot id: E3DQU0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

572479:HPRAE RS09385
gene id: 572479:HPRAE_RS09385
uniprot id: E3DQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS02655
gene id: 572479:HPRAE_RS02655
uniprot id: E3DPC8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS03505
gene id: 572479:HPRAE_RS03505
uniprot id: E3DQE5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

572479:HPRAE RS08455
gene id: 572479:HPRAE_RS08455
uniprot id: E3DPU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS06630
gene id: 572479:HPRAE_RS06630
uniprot id: E3DMT9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

572479:HPRAE RS11135
gene id: 572479:HPRAE_RS11135
uniprot id: E3DP21
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS01540
gene id: 572479:HPRAE_RS01540
uniprot id: E3DN53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

572479:HPRAE RS04945
gene id: 572479:HPRAE_RS04945
uniprot id: E3DRY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

572479:HPRAE RS07695
gene id: 572479:HPRAE_RS07695
uniprot id: E3DNZ8
names: Similarity
messages: Belongs to the peptidase C56 family.

572479:HPRAE RS01030
gene id: 572479:HPRAE_RS01030
uniprot id: E3DMN2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

572479:HPRAE RS01505
gene id: 572479:HPRAE_RS01505
uniprot id: E3DN45
names: Similarity
messages: Belongs to the UPF0251 family.

572479:HPRAE RS02740
gene id: 572479:HPRAE_RS02740
uniprot id: E3DPM1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

572479:HPRAE RS00530
gene id: 572479:HPRAE_RS00530
uniprot id: E3DLZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

572479:HPRAE RS09480
gene id: 572479:HPRAE_RS09480
uniprot id: E3DQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

572479:HPRAE RS07465
gene id: 572479:HPRAE_RS07465
uniprot id: E3DNN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS01110
gene id: 572479:HPRAE_RS01110
uniprot id: E3DMP9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

572479:HPRAE RS07660
gene id: 572479:HPRAE_RS07660
uniprot id: E3DNS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

572479:HPRAE RS03650
gene id: 572479:HPRAE_RS03650
uniprot id: E3DQG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

572479:HPRAE RS04755
gene id: 572479:HPRAE_RS04755
uniprot id: E3DRN3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

572479:HPRAE RS06545
gene id: 572479:HPRAE_RS06545
uniprot id: E3DMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

572479:HPRAE RS05260
gene id: 572479:HPRAE_RS05260
uniprot id: E3DLC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

572479:HPRAE RS03410
gene id: 572479:HPRAE_RS03410
uniprot id: E3DQ72
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

572479:HPRAE RS03295
gene id: 572479:HPRAE_RS03295
uniprot id: E3DQ49
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

572479:HPRAE RS10080
gene id: 572479:HPRAE_RS10080
uniprot id: E3DRF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

572479:HPRAE RS02750
gene id: 572479:HPRAE_RS02750
uniprot id: E3DPM3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

572479:HPRAE RS06370
gene id: 572479:HPRAE_RS06370
uniprot id: E3DMG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

572479:HPRAE RS07425
gene id: 572479:HPRAE_RS07425
uniprot id: E3DNM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

572479:HPRAE RS05200
gene id: 572479:HPRAE_RS05200
uniprot id: E3DLB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

572479:HPRAE RS05650
gene id: 572479:HPRAE_RS05650
uniprot id: E3DLP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS10170
gene id: 572479:HPRAE_RS10170
uniprot id: E3DRH6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS03170
gene id: 572479:HPRAE_RS03170
uniprot id: E3DQ26
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

572479:HPRAE RS06335
gene id: 572479:HPRAE_RS06335
uniprot id: E3DMG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

572479:HPRAE RS04635
gene id: 572479:HPRAE_RS04635
uniprot id: E3DRK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

572479:HPRAE RS07825
gene id: 572479:HPRAE_RS07825
uniprot id: E3DP24
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

572479:HPRAE RS01405
gene id: 572479:HPRAE_RS01405
uniprot id: E3DN25
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS04640
gene id: 572479:HPRAE_RS04640
uniprot id: E3DRL0
names: Similarity
messages: Belongs to the TlyA family.

572479:HPRAE RS03690
gene id: 572479:HPRAE_RS03690
uniprot id: E3DQH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS04260
gene id: 572479:HPRAE_RS04260
uniprot id: E3DR69
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS02025
gene id: 572479:HPRAE_RS02025
uniprot id: E3DNT1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

572479:HPRAE RS03430
gene id: 572479:HPRAE_RS03430
uniprot id: E3DQD0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

572479:HPRAE RS10625
gene id: 572479:HPRAE_RS10625
uniprot id: E3DS45
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

572479:HPRAE RS00995
gene id: 572479:HPRAE_RS00995
uniprot id: E3DMM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS10055
gene id: 572479:HPRAE_RS10055
uniprot id: E3DRF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

572479:HPRAE RS02995
gene id: 572479:HPRAE_RS02995
uniprot id: E3DPS2
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

572479:HPRAE RS10670
gene id: 572479:HPRAE_RS10670
uniprot id: E3DS54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

572479:HPRAE RS10255
gene id: 572479:HPRAE_RS10255
uniprot id: E3DRR1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

572479:HPRAE RS10140
gene id: 572479:HPRAE_RS10140
uniprot id: E3DRH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

572479:HPRAE RS03150
gene id: 572479:HPRAE_RS03150
uniprot id: E3DQ22
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

572479:HPRAE RS00920
gene id: 572479:HPRAE_RS00920
uniprot id: E3DME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

572479:HPRAE RS03205
gene id: 572479:HPRAE_RS03205
uniprot id: E3DQ32
names: Similarity
messages: Belongs to the UPF0237 family.

572479:HPRAE RS10360
gene id: 572479:HPRAE_RS10360
uniprot id: E3DRT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

572479:HPRAE RS10085
gene id: 572479:HPRAE_RS10085
uniprot id: E3DRF9
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS04100
gene id: 572479:HPRAE_RS04100
uniprot id: E3DQY0
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

572479:HPRAE RS10095
gene id: 572479:HPRAE_RS10095
uniprot id: E3DRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

572479:HPRAE RS06155
gene id: 572479:HPRAE_RS06155
uniprot id: E3DM57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

572479:HPRAE RS07590
gene id: 572479:HPRAE_RS07590
uniprot id: E3DNR2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

572479:HPRAE RS04875
gene id: 572479:HPRAE_RS04875
uniprot id: E3DRX4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS06100
gene id: 572479:HPRAE_RS06100
uniprot id: E3DM47
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

572479:HPRAE RS00510
gene id: 572479:HPRAE_RS00510
uniprot id: E3DLZ4
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS10865
gene id: 572479:HPRAE_RS10865
uniprot id: E3DPN1
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

572479:HPRAE RS00165
gene id: 572479:HPRAE_RS00165
uniprot id: E3DLK8
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

572479:HPRAE RS04745
gene id: 572479:HPRAE_RS04745
uniprot id: E3DRN1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

572479:HPRAE RS03370
gene id: 572479:HPRAE_RS03370
uniprot id: E3DQ64
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

572479:HPRAE RS03460
gene id: 572479:HPRAE_RS03460
uniprot id: E3DQD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

572479:HPRAE RS05090
gene id: 572479:HPRAE_RS05090
uniprot id: E3DS17
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS00835
gene id: 572479:HPRAE_RS00835
uniprot id: E3DMC4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS08515
gene id: 572479:HPRAE_RS08515
uniprot id: E3DPV4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

572479:HPRAE RS00825
gene id: 572479:HPRAE_RS00825
uniprot id: E3DMC2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS06675
gene id: 572479:HPRAE_RS06675
uniprot id: E3DMU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

572479:HPRAE RS10355
gene id: 572479:HPRAE_RS10355
uniprot id: E3DRT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

572479:HPRAE RS09515
gene id: 572479:HPRAE_RS09515
uniprot id: E3DQY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

572479:HPRAE RS08250
gene id: 572479:HPRAE_RS08250
uniprot id: E3DPI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

572479:HPRAE RS03390
gene id: 572479:HPRAE_RS03390
uniprot id: E3DQ68
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

572479:HPRAE RS00080
gene id: 572479:HPRAE_RS00080
uniprot id: E3DLJ1
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

572479:HPRAE RS08740
gene id: 572479:HPRAE_RS08740
uniprot id: E3DPZ8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

572479:HPRAE RS06475
gene id: 572479:HPRAE_RS06475
uniprot id: E3DMJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

572479:HPRAE RS10785
gene id: 572479:HPRAE_RS10785
uniprot id: E3DS77
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS06890
gene id: 572479:HPRAE_RS06890
uniprot id: E3DMZ0
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

572479:HPRAE RS05655
gene id: 572479:HPRAE_RS05655
uniprot id: E3DLP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS00615
gene id: 572479:HPRAE_RS00615
uniprot id: E3DM81
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

572479:HPRAE RS07900
gene id: 572479:HPRAE_RS07900
uniprot id: E3DM13
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

572479:HPRAE RS01420
gene id: 572479:HPRAE_RS01420
uniprot id: E3DN28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

572479:HPRAE RS08670
gene id: 572479:HPRAE_RS08670
uniprot id: E3DPY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

572479:HPRAE RS01885
gene id: 572479:HPRAE_RS01885
uniprot id: E3DNJ0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

572479:HPRAE RS04975
gene id: 572479:HPRAE_RS04975
uniprot id: E3DRZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

572479:HPRAE RS04070
gene id: 572479:HPRAE_RS04070
uniprot id: E3DQX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

572479:HPRAE RS05600
gene id: 572479:HPRAE_RS05600
uniprot id: E3DLN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

572479:HPRAE RS10125
gene id: 572479:HPRAE_RS10125
uniprot id: E3DRG7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

572479:HPRAE RS10590
gene id: 572479:HPRAE_RS10590
uniprot id: E3DS38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS08535
gene id: 572479:HPRAE_RS08535
uniprot id: E3DPV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

572479:HPRAE RS03445
gene id: 572479:HPRAE_RS03445
uniprot id: E3DQD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

572479:HPRAE RS01970
gene id: 572479:HPRAE_RS01970
uniprot id: E3DNK7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

572479:HPRAE RS03380
gene id: 572479:HPRAE_RS03380
uniprot id: E3DQ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

572479:HPRAE RS00795
gene id: 572479:HPRAE_RS00795
uniprot id: E3DMB6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS05300
gene id: 572479:HPRAE_RS05300
uniprot id: E3DLD5
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS08330
gene id: 572479:HPRAE_RS08330
uniprot id: E3DPJ5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

572479:HPRAE RS03560
gene id: 572479:HPRAE_RS03560
uniprot id: E3DQF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS10660
gene id: 572479:HPRAE_RS10660
uniprot id: E3DS52
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

572479:HPRAE RS09635
gene id: 572479:HPRAE_RS09635
uniprot id: E3DR12
names: Similarity
messages: Belongs to the bacterial flagellin family.

572479:HPRAE RS03740
gene id: 572479:HPRAE_RS03740
uniprot id: E3DQI7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

572479:HPRAE RS09970
gene id: 572479:HPRAE_RS09970
uniprot id: E3DRD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

572479:HPRAE RS06375
gene id: 572479:HPRAE_RS06375
uniprot id: E3DMH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

572479:HPRAE RS08285
gene id: 572479:HPRAE_RS08285
uniprot id: E3DPI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

572479:HPRAE RS09440
gene id: 572479:HPRAE_RS09440
uniprot id: E3DQQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS05265
gene id: 572479:HPRAE_RS05265
uniprot id: E3DLC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

572479:HPRAE RS09470
gene id: 572479:HPRAE_RS09470
uniprot id: E3DQQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS08185
gene id: 572479:HPRAE_RS08185
uniprot id: E3DPG8
names: Similarity
messages: Belongs to the RecJ family.

572479:HPRAE RS02730
gene id: 572479:HPRAE_RS02730
uniprot id: E3DPL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

572479:HPRAE RS06680
gene id: 572479:HPRAE_RS06680
uniprot id: E3DMU9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

572479:HPRAE RS02065
gene id: 572479:HPRAE_RS02065
uniprot id: E3DNT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS00640
gene id: 572479:HPRAE_RS00640
uniprot id: E3DM86
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

572479:HPRAE RS06760
gene id: 572479:HPRAE_RS06760
uniprot id: E3DMW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

572479:HPRAE RS00925
gene id: 572479:HPRAE_RS00925
uniprot id: E3DME3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

572479:HPRAE RS04925
gene id: 572479:HPRAE_RS04925
uniprot id: E3DRY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

572479:HPRAE RS03795
gene id: 572479:HPRAE_RS03795
uniprot id: E3DQR9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS01120
gene id: 572479:HPRAE_RS01120
uniprot id: E3DMQ1
names: Similarity
messages: Belongs to the peptidase S16 family.

572479:HPRAE RS04055
gene id: 572479:HPRAE_RS04055
uniprot id: E3DQX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

572479:HPRAE RS07260
gene id: 572479:HPRAE_RS07260
uniprot id: E3DNC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS09020
gene id: 572479:HPRAE_RS09020
uniprot id: E3DQ99
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS03405
gene id: 572479:HPRAE_RS03405
uniprot id: E3DQ71
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

572479:HPRAE RS08825
gene id: 572479:HPRAE_RS08825
uniprot id: E3DQ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

572479:HPRAE RS09310
gene id: 572479:HPRAE_RS09310
uniprot id: E3DQM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

572479:HPRAE RS09805
gene id: 572479:HPRAE_RS09805
uniprot id: E3DR46
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

572479:HPRAE RS03165
gene id: 572479:HPRAE_RS03165
uniprot id: E3DQ25
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

572479:HPRAE RS08500
gene id: 572479:HPRAE_RS08500
uniprot id: E3DPV1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

572479:HPRAE RS06345
gene id: 572479:HPRAE_RS06345
uniprot id: E3DMG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

572479:HPRAE RS03005
gene id: 572479:HPRAE_RS03005
uniprot id: E3DPS4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

572479:HPRAE RS00205
gene id: 572479:HPRAE_RS00205
uniprot id: E3DLL6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

572479:HPRAE RS08835
gene id: 572479:HPRAE_RS08835
uniprot id: E3DQ78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

572479:HPRAE RS06330
gene id: 572479:HPRAE_RS06330
uniprot id: E3DMG1
names: Similarity
messages: Belongs to the transpeptidase family.

572479:HPRAE RS07760
gene id: 572479:HPRAE_RS07760
uniprot id: E3DP11
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

572479:HPRAE RS02320
gene id: 572479:HPRAE_RS02320
uniprot id: E3DNY9
names: Similarity
messages: Belongs to the peptidase C69 family.

572479:HPRAE RS03050
gene id: 572479:HPRAE_RS03050
uniprot id: E3DPT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

572479:HPRAE RS00805
gene id: 572479:HPRAE_RS00805
uniprot id: E3DMB8
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

572479:HPRAE RS10730
gene id: 572479:HPRAE_RS10730
uniprot id: E3DS66
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

572479:HPRAE RS03625
gene id: 572479:HPRAE_RS03625
uniprot id: E3DQG4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

572479:HPRAE RS09050
gene id: 572479:HPRAE_RS09050
uniprot id: E3DQA5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

572479:HPRAE RS05030
gene id: 572479:HPRAE_RS05030
uniprot id: E3DS05
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

572479:HPRAE RS04620
gene id: 572479:HPRAE_RS04620
uniprot id: E3DRK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

572479:HPRAE RS05045
gene id: 572479:HPRAE_RS05045
uniprot id: E3DS08
names: Similarity
messages: Belongs to the peptidase M18 family.

572479:HPRAE RS04455
gene id: 572479:HPRAE_RS04455
uniprot id: E3DRA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS08885
gene id: 572479:HPRAE_RS08885
uniprot id: E3DQ88
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

572479:HPRAE RS06220
gene id: 572479:HPRAE_RS06220
uniprot id: E3DM70
names: Similarity
messages: Belongs to the FBPase class 3 family.

572479:HPRAE RS03350
gene id: 572479:HPRAE_RS03350
uniprot id: E3DQ60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

572479:HPRAE RS04485
gene id: 572479:HPRAE_RS04485
uniprot id: E3DRH9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

572479:HPRAE RS08785
gene id: 572479:HPRAE_RS08785
uniprot id: E3DQ03
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

572479:HPRAE RS03075
gene id: 572479:HPRAE_RS03075
uniprot id: E3DQ12
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS07420
gene id: 572479:HPRAE_RS07420
uniprot id: E3DNM8
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS09760
gene id: 572479:HPRAE_RS09760
uniprot id: E3DR37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

572479:HPRAE RS04725
gene id: 572479:HPRAE_RS04725
uniprot id: E3DRM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

572479:HPRAE RS00605
gene id: 572479:HPRAE_RS00605
uniprot id: E3DM13
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

572479:HPRAE RS00965
gene id: 572479:HPRAE_RS00965
uniprot id: E3DMM0
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS04920
gene id: 572479:HPRAE_RS04920
uniprot id: E3DRY3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

572479:HPRAE RS04605
gene id: 572479:HPRAE_RS04605
uniprot id: E3DRK3
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

572479:HPRAE RS07605
gene id: 572479:HPRAE_RS07605
uniprot id: E3DNR5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS03395
gene id: 572479:HPRAE_RS03395
uniprot id: E3DQ69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

572479:HPRAE RS05875
gene id: 572479:HPRAE_RS05875
uniprot id: E3DLT7
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS06285
gene id: 572479:HPRAE_RS06285
uniprot id: E3DMF3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

572479:HPRAE RS01650
gene id: 572479:HPRAE_RS01650
uniprot id: E3DN74
names: Similarity
messages: Belongs to the polysaccharide synthase family.

572479:HPRAE RS10430
gene id: 572479:HPRAE_RS10430
uniprot id: E3DRU0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS10615
gene id: 572479:HPRAE_RS10615
uniprot id: E3DS43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS04235
gene id: 572479:HPRAE_RS04235
uniprot id: E3DR64
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

572479:HPRAE RS10705
gene id: 572479:HPRAE_RS10705
uniprot id: E3DS61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

572479:HPRAE RS09655
gene id: 572479:HPRAE_RS09655
uniprot id: E3DR16
names: Similarity
messages: Belongs to the FlgM family.

572479:HPRAE RS01235
gene id: 572479:HPRAE_RS01235
uniprot id: E3DMS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS09775
gene id: 572479:HPRAE_RS09775
uniprot id: E3DR40
names: Similarity
messages: Belongs to the UPF0597 family.

572479:HPRAE RS03470
gene id: 572479:HPRAE_RS03470
uniprot id: E3DQD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

572479:HPRAE RS06725
gene id: 572479:HPRAE_RS06725
uniprot id: E3DMV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

572479:HPRAE RS08385
gene id: 572479:HPRAE_RS08385
uniprot id: E3DPK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

572479:HPRAE RS03485
gene id: 572479:HPRAE_RS03485
uniprot id: E3DQE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

572479:HPRAE RS10710
gene id: 572479:HPRAE_RS10710
uniprot id: E3DS62
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

572479:HPRAE RS05305
gene id: 572479:HPRAE_RS05305
uniprot id: E3DLD6
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

572479:HPRAE RS09570
gene id: 572479:HPRAE_RS09570
uniprot id: E3DQZ8
names: Similarity
messages: Belongs to the BMP lipoprotein family.

572479:HPRAE RS05225
gene id: 572479:HPRAE_RS05225
uniprot id: E3DLC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

572479:HPRAE RS10300
gene id: 572479:HPRAE_RS10300
uniprot id: E3DRS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS09475
gene id: 572479:HPRAE_RS09475
uniprot id: E3DQQ7
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

572479:HPRAE RS02385
gene id: 572479:HPRAE_RS02385
uniprot id: E3DP74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

572479:HPRAE RS03940
gene id: 572479:HPRAE_RS03940
uniprot id: E3DQU8
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS08995
gene id: 572479:HPRAE_RS08995
uniprot id: E3DQ94
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS09100
gene id: 572479:HPRAE_RS09100
uniprot id: E3DQB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

572479:HPRAE RS09835
gene id: 572479:HPRAE_RS09835
uniprot id: E3DR52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

572479:HPRAE RS08900
gene id: 572479:HPRAE_RS08900
uniprot id: E3DQ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

572479:HPRAE RS09485
gene id: 572479:HPRAE_RS09485
uniprot id: E3DQQ9
names: Similarity
messages: Belongs to the class-I fumarase family.

572479:HPRAE RS04680
gene id: 572479:HPRAE_RS04680
uniprot id: E3DRL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

572479:HPRAE RS03210
gene id: 572479:HPRAE_RS03210
uniprot id: E3DQ33
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

572479:HPRAE RS03045
gene id: 572479:HPRAE_RS03045
uniprot id: E3DPT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

572479:HPRAE RS08050
gene id: 572479:HPRAE_RS08050
uniprot id: E3DPE0
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

572479:HPRAE RS00160
gene id: 572479:HPRAE_RS00160
uniprot id: E3DLK7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS06920
gene id: 572479:HPRAE_RS06920
uniprot id: E3DMZ6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

572479:HPRAE RS05900
gene id: 572479:HPRAE_RS05900
uniprot id: E3DLU2
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS04905
gene id: 572479:HPRAE_RS04905
uniprot id: E3DRY0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS06125
gene id: 572479:HPRAE_RS06125
uniprot id: E3DM51
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

572479:HPRAE RS02900
gene id: 572479:HPRAE_RS02900
uniprot id: E3DPQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.

572479:HPRAE RS00970
gene id: 572479:HPRAE_RS00970
uniprot id: E3DMM1
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS08550
gene id: 572479:HPRAE_RS08550
uniprot id: E3DPW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

572479:HPRAE RS03720
gene id: 572479:HPRAE_RS03720
uniprot id: E3DQI3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

572479:HPRAE RS04585
gene id: 572479:HPRAE_RS04585
uniprot id: E3DRJ9
names: Similarity
messages: Belongs to the asp23 family.

572479:HPRAE RS02605
gene id: 572479:HPRAE_RS02605
uniprot id: E3DPB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

572479:HPRAE RS09690
gene id: 572479:HPRAE_RS09690
uniprot id: E3DR23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS09795
gene id: 572479:HPRAE_RS09795
uniprot id: E3DR44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

572479:HPRAE RS04370
gene id: 572479:HPRAE_RS04370
uniprot id: E3DR91
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS10920
gene id: 572479:HPRAE_RS10920
uniprot id: E3DMV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

572479:HPRAE RS03215
gene id: 572479:HPRAE_RS03215
uniprot id: E3DQ34
names: Similarity
messages: Belongs to the aldose epimerase family.

572479:HPRAE RS02985
gene id: 572479:HPRAE_RS02985
uniprot id: E3DPS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

572479:HPRAE RS02050
gene id: 572479:HPRAE_RS02050
uniprot id: E3DNT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS08715
gene id: 572479:HPRAE_RS08715
uniprot id: E3DPZ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS08475
gene id: 572479:HPRAE_RS08475
uniprot id: E3DPU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

572479:HPRAE RS10800
gene id: 572479:HPRAE_RS10800
uniprot id: E3DS80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

572479:HPRAE RS03030
gene id: 572479:HPRAE_RS03030
uniprot id: E3DPS9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

572479:HPRAE RS08525
gene id: 572479:HPRAE_RS08525
uniprot id: E3DPV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

572479:HPRAE RS00565
gene id: 572479:HPRAE_RS00565
uniprot id: E3DM05
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

572479:HPRAE RS03275
gene id: 572479:HPRAE_RS03275
uniprot id: E3DQ45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

572479:HPRAE RS07845
gene id: 572479:HPRAE_RS07845
uniprot id: E3DP28
names: Similarity
messages: Belongs to the CobH/CbiC family.

572479:HPRAE RS01860
gene id: 572479:HPRAE_RS01860
uniprot id: E3DNI6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

572479:HPRAE RS03910
gene id: 572479:HPRAE_RS03910
uniprot id: E3DQU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

572479:HPRAE RS05485
gene id: 572479:HPRAE_RS05485
uniprot id: E3DLH1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

572479:HPRAE RS03755
gene id: 572479:HPRAE_RS03755
uniprot id: E3DQJ0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

572479:HPRAE RS08675
gene id: 572479:HPRAE_RS08675
uniprot id: E3DPY5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

572479:HPRAE RS04230
gene id: 572479:HPRAE_RS04230
uniprot id: E3DR63
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

572479:HPRAE RS00235
gene id: 572479:HPRAE_RS00235
uniprot id: E3DLM2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

572479:HPRAE RS06235
gene id: 572479:HPRAE_RS06235
uniprot id: E3DM73
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

572479:HPRAE RS04795
gene id: 572479:HPRAE_RS04795
uniprot id: E3DRP1
names: Similarity
messages: Belongs to the UPF0102 family.

572479:HPRAE RS05295
gene id: 572479:HPRAE_RS05295
uniprot id: E3DLD4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

572479:HPRAE RS02885
gene id: 572479:HPRAE_RS02885
uniprot id: E3DPQ0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

572479:HPRAE RS08680
gene id: 572479:HPRAE_RS08680
uniprot id: E3DPY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

572479:HPRAE RS07330
gene id: 572479:HPRAE_RS07330
uniprot id: E3DNE2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

572479:HPRAE RS03885
gene id: 572479:HPRAE_RS03885
uniprot id: E3DQT7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

572479:HPRAE RS02430
gene id: 572479:HPRAE_RS02430
uniprot id: E3DP83
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

572479:HPRAE RS10350
gene id: 572479:HPRAE_RS10350
uniprot id: E3DRT0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

572479:HPRAE RS00830
gene id: 572479:HPRAE_RS00830
uniprot id: E3DMC3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

572479:HPRAE RS08625
gene id: 572479:HPRAE_RS08625
uniprot id: E3DPX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

572479:HPRAE RS09670
gene id: 572479:HPRAE_RS09670
uniprot id: E3DR19
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS03000
gene id: 572479:HPRAE_RS03000
uniprot id: E3DPS3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

572479:HPRAE RS07820
gene id: 572479:HPRAE_RS07820
uniprot id: E3DP23
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

572479:HPRAE RS09875
gene id: 572479:HPRAE_RS09875
uniprot id: E3DRB7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

572479:HPRAE RS10340
gene id: 572479:HPRAE_RS10340
uniprot id: E3DRS8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

572479:HPRAE RS04865
gene id: 572479:HPRAE_RS04865
uniprot id: E3DRX2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

572479:HPRAE RS00370
gene id: 572479:HPRAE_RS00370
uniprot id: E3DLW6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

572479:HPRAE RS03500
gene id: 572479:HPRAE_RS03500
uniprot id: E3DQE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

572479:HPRAE RS05835
gene id: 572479:HPRAE_RS05835
uniprot id: E3DLT2
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

572479:HPRAE RS08280
gene id: 572479:HPRAE_RS08280
uniprot id: E3DPI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

572479:HPRAE RS10240
gene id: 572479:HPRAE_RS10240
uniprot id: E3DRQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

572479:HPRAE RS03115
gene id: 572479:HPRAE_RS03115
uniprot id: E3DQ20
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

572479:HPRAE RS10580
gene id: 572479:HPRAE_RS10580
uniprot id: E3DS36
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

572479:HPRAE RS08840
gene id: 572479:HPRAE_RS08840
uniprot id: E3DQ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

572479:HPRAE RS04830
gene id: 572479:HPRAE_RS04830
uniprot id: E3DRW5
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS09560
gene id: 572479:HPRAE_RS09560
uniprot id: E3DQZ6
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS06805
gene id: 572479:HPRAE_RS06805
uniprot id: E3DMX2
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS05115
gene id: 572479:HPRAE_RS05115
uniprot id: E3DS22
names: Similarity
messages: Belongs to the BMP lipoprotein family.

572479:HPRAE RS05100
gene id: 572479:HPRAE_RS05100
uniprot id: E3DS19
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS02520
gene id: 572479:HPRAE_RS02520
uniprot id: E3DPA1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

572479:HPRAE RS02845
gene id: 572479:HPRAE_RS02845
uniprot id: E3DPP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

572479:HPRAE RS07770
gene id: 572479:HPRAE_RS07770
uniprot id: E3DP13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

572479:HPRAE RS01955
gene id: 572479:HPRAE_RS01955
uniprot id: E3DNK4
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

572479:HPRAE RS05065
gene id: 572479:HPRAE_RS05065
uniprot id: E3DS12
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

572479:HPRAE RS00500
gene id: 572479:HPRAE_RS00500
uniprot id: E3DLZ2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

572479:HPRAE RS04690
gene id: 572479:HPRAE_RS04690
uniprot id: E3DRM0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

572479:HPRAE RS04580
gene id: 572479:HPRAE_RS04580
uniprot id: E3DRJ8
names: Similarity
messages: Belongs to the asp23 family.

572479:HPRAE RS02095
gene id: 572479:HPRAE_RS02095
uniprot id: E3DNU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

572479:HPRAE RS02800
gene id: 572479:HPRAE_RS02800
uniprot id: E3DPN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

572479:HPRAE RS02070
gene id: 572479:HPRAE_RS02070
uniprot id: E3DNT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS09985
gene id: 572479:HPRAE_RS09985
uniprot id: E3DRD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

572479:HPRAE RS04175
gene id: 572479:HPRAE_RS04175
uniprot id: E3DR60
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

572479:HPRAE RS09240
gene id: 572479:HPRAE_RS09240
uniprot id: E3DQK9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

572479:HPRAE RS07910
gene id: 572479:HPRAE_RS07910
uniprot id: E3DP41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

572479:HPRAE RS02225
gene id: 572479:HPRAE_RS02225
uniprot id: E3DNX0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

572479:HPRAE RS00385
gene id: 572479:HPRAE_RS00385
uniprot id: E3DLW9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

572479:HPRAE RS05710
gene id: 572479:HPRAE_RS05710
uniprot id: E3DLQ6
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS02760
gene id: 572479:HPRAE_RS02760
uniprot id: E3DPM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

572479:HPRAE RS03160
gene id: 572479:HPRAE_RS03160
uniprot id: E3DQ24
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

572479:HPRAE RS02420
gene id: 572479:HPRAE_RS02420
uniprot id: E3DP81
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

572479:HPRAE RS03950
gene id: 572479:HPRAE_RS03950
uniprot id: E3DQV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

572479:HPRAE RS00960
gene id: 572479:HPRAE_RS00960
uniprot id: E3DML9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS08510
gene id: 572479:HPRAE_RS08510
uniprot id: E3DPV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

572479:HPRAE RS07755
gene id: 572479:HPRAE_RS07755
uniprot id: E3DP10
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

572479:HPRAE RS00505
gene id: 572479:HPRAE_RS00505
uniprot id: E3DLZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

572479:HPRAE RS00310
gene id: 572479:HPRAE_RS00310
uniprot id: E3DLV5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

572479:HPRAE RS03995
gene id: 572479:HPRAE_RS03995
uniprot id: E3DQV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

572479:HPRAE RS00630
gene id: 572479:HPRAE_RS00630
uniprot id: E3DM84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

572479:HPRAE RS04845
gene id: 572479:HPRAE_RS04845
uniprot id: E3DRW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

572479:HPRAE RS06775
gene id: 572479:HPRAE_RS06775
uniprot id: E3DMW6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

572479:HPRAE RS03535
gene id: 572479:HPRAE_RS03535
uniprot id: E3DQF1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

572479:HPRAE RS03775
gene id: 572479:HPRAE_RS03775
uniprot id: E3DQR5
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

572479:HPRAE RS03680
gene id: 572479:HPRAE_RS03680
uniprot id: E3DQH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

572479:HPRAE RS06005
gene id: 572479:HPRAE_RS06005
uniprot id: E3DM31
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

572479:HPRAE RS03495
gene id: 572479:HPRAE_RS03495
uniprot id: E3DQE3
names: Similarity
messages: Belongs to the RecJ family.

572479:HPRAE RS06915
gene id: 572479:HPRAE_RS06915
uniprot id: E3DMZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

572479:HPRAE RS01195
gene id: 572479:HPRAE_RS01195
uniprot id: E3DMR6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS01400
gene id: 572479:HPRAE_RS01400
uniprot id: E3DN24
names: Similarity
messages: Belongs to the EutP/PduV family.

572479:HPRAE RS02695
gene id: 572479:HPRAE_RS02695
uniprot id: E3DPD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

572479:HPRAE RS09015
gene id: 572479:HPRAE_RS09015
uniprot id: E3DQ98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

572479:HPRAE RS00955
gene id: 572479:HPRAE_RS00955
uniprot id: E3DME9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

572479:HPRAE RS06860
gene id: 572479:HPRAE_RS06860
uniprot id: E3DMY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

572479:HPRAE RS10425
gene id: 572479:HPRAE_RS10425
uniprot id: E3DRT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

572479:HPRAE RS05085
gene id: 572479:HPRAE_RS05085
uniprot id: E3DS16
names: Similarity
messages: Belongs to the EamA transporter family.

572479:HPRAE RS08710
gene id: 572479:HPRAE_RS08710
uniprot id: E3DPZ2
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

572479:HPRAE RS07320
gene id: 572479:HPRAE_RS07320
uniprot id: E3DNE0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

572479:HPRAE RS00515
gene id: 572479:HPRAE_RS00515
uniprot id: E3DLZ5
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

572479:HPRAE RS08495
gene id: 572479:HPRAE_RS08495
uniprot id: E3DPV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

572479:HPRAE RS01575
gene id: 572479:HPRAE_RS01575
uniprot id: E3DN60
names: Similarity
messages: Belongs to the WrbA family.

572479:HPRAE RS07840
gene id: 572479:HPRAE_RS07840
uniprot id: E3DP27
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

572479:HPRAE RS09810
gene id: 572479:HPRAE_RS09810
uniprot id: E3DR47
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

572479:HPRAE RS09735
gene id: 572479:HPRAE_RS09735
uniprot id: E3DR32
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

572479:HPRAE RS05885
gene id: 572479:HPRAE_RS05885
uniprot id: E3DLT9
names: Similarity
messages: Belongs to the UPF0045 family.

572479:HPRAE RS01305
gene id: 572479:HPRAE_RS01305
uniprot id: E3DN06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

572479:HPRAE RS00450
gene id: 572479:HPRAE_RS00450
uniprot id: E3DLY2
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS03945
gene id: 572479:HPRAE_RS03945
uniprot id: E3DQU9
names: Similarity
messages: Belongs to the peptidase S16 family.

572479:HPRAE RS03055
gene id: 572479:HPRAE_RS03055
uniprot id: E3DQ08
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS08705
gene id: 572479:HPRAE_RS08705
uniprot id: E3DPZ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

572479:HPRAE RS04995
gene id: 572479:HPRAE_RS04995
uniprot id: E3DRZ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

572479:HPRAE RS09430
gene id: 572479:HPRAE_RS09430
uniprot id: E3DQP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

572479:HPRAE RS04895
gene id: 572479:HPRAE_RS04895
uniprot id: E3DRX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

572479:HPRAE RS03525
gene id: 572479:HPRAE_RS03525
uniprot id: E3DQE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

572479:HPRAE RS10675
gene id: 572479:HPRAE_RS10675
uniprot id: E3DS55
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

572479:HPRAE RS01220
gene id: 572479:HPRAE_RS01220
uniprot id: E3DMS1
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

572479:HPRAE RS05320
gene id: 572479:HPRAE_RS05320
uniprot id: E3DLD9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

572479:HPRAE RS00900
gene id: 572479:HPRAE_RS00900
uniprot id: E3DMD8
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

572479:HPRAE RS07725
gene id: 572479:HPRAE_RS07725
uniprot id: E3DP04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

572479:HPRAE RS06435
gene id: 572479:HPRAE_RS06435
uniprot id: E3DMI2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

572479:HPRAE RS05325
gene id: 572479:HPRAE_RS05325
uniprot id: E3DLE0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

572479:HPRAE RS05870
gene id: 572479:HPRAE_RS05870
uniprot id: E3DLT6
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS08175
gene id: 572479:HPRAE_RS08175
uniprot id: E3DPG6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

572479:HPRAE RS08615
gene id: 572479:HPRAE_RS08615
uniprot id: E3DPX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

572479:HPRAE RS05715
gene id: 572479:HPRAE_RS05715
uniprot id: E3DLQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

572479:HPRAE RS04950
gene id: 572479:HPRAE_RS04950
uniprot id: E3DRY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

572479:HPRAE RS05095
gene id: 572479:HPRAE_RS05095
uniprot id: E3DS18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

572479:HPRAE RS07450
gene id: 572479:HPRAE_RS07450
uniprot id: E3DNN4
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS03760
gene id: 572479:HPRAE_RS03760
uniprot id: E3DQJ1
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

572479:HPRAE RS03915
gene id: 572479:HPRAE_RS03915
uniprot id: E3DQU3
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS08080
gene id: 572479:HPRAE_RS08080
uniprot id: E3DPE7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

572479:HPRAE RS07925
gene id: 572479:HPRAE_RS07925
uniprot id: E3DM09
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

572479:HPRAE RS02240
gene id: 572479:HPRAE_RS02240
uniprot id: E3DNX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

572479:HPRAE RS08590
gene id: 572479:HPRAE_RS08590
uniprot id: E3DPW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

572479:HPRAE RS04160
gene id: 572479:HPRAE_RS04160
uniprot id: E3DR58
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

572479:HPRAE RS03710
gene id: 572479:HPRAE_RS03710
uniprot id: E3DQI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

572479:HPRAE RS07885
gene id: 572479:HPRAE_RS07885
uniprot id: E3DP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

572479:HPRAE RS06705
gene id: 572479:HPRAE_RS06705
uniprot id: E3DMV4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

572479:HPRAE RS10135
gene id: 572479:HPRAE_RS10135
uniprot id: E3DRG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

572479:HPRAE RS00150
gene id: 572479:HPRAE_RS00150
uniprot id: E3DLK5
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

572479:HPRAE RS08005
gene id: 572479:HPRAE_RS08005
uniprot id: E3DP60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

572479:HPRAE RS05590
gene id: 572479:HPRAE_RS05590
uniprot id: E3DLN2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

572479:HPRAE RS03545
gene id: 572479:HPRAE_RS03545
uniprot id: E3DQF3
names: Similarity
messages: Belongs to the IMPACT family.

572479:HPRAE RS06815
gene id: 572479:HPRAE_RS06815
uniprot id: E3DMX4
names: Similarity
messages: Belongs to the Ahb/Nir family.

572479:HPRAE RS02270
gene id: 572479:HPRAE_RS02270
uniprot id: E3DNX9
names: Similarity
messages: Belongs to the thioredoxin family.

572479:HPRAE RS00030
gene id: 572479:HPRAE_RS00030
uniprot id: E3DLI7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

572479:HPRAE RS08540
gene id: 572479:HPRAE_RS08540
uniprot id: E3DPV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

572479:HPRAE RS10190
gene id: 572479:HPRAE_RS10190
uniprot id: E3DRP8
names: Similarity
messages: Belongs to the thioredoxin family.

572479:HPRAE RS05825
gene id: 572479:HPRAE_RS05825
uniprot id: E3DLT0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

572479:HPRAE RS07440
gene id: 572479:HPRAE_RS07440
uniprot id: E3DNN2
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

572479:HPRAE RS08245
gene id: 572479:HPRAE_RS08245
uniprot id: E3DPI0
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

572479:HPRAE RS02890
gene id: 572479:HPRAE_RS02890
uniprot id: E3DPQ1
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

572479:HPRAE RS03510
gene id: 572479:HPRAE_RS03510
uniprot id: E3DQE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

572479:HPRAE RS06390
gene id: 572479:HPRAE_RS06390
uniprot id: E3DMH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

572479:HPRAE RS04005
gene id: 572479:HPRAE_RS04005
uniprot id: E3DQW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

572479:HPRAE RS04965
gene id: 572479:HPRAE_RS04965
uniprot id: E3DRZ2
names: Similarity
messages: Belongs to the ribF family.

572479:HPRAE RS05605
gene id: 572479:HPRAE_RS05605
uniprot id: E3DLN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

572479:HPRAE RS10075
gene id: 572479:HPRAE_RS10075
uniprot id: E3DRF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

572479:HPRAE RS07595
gene id: 572479:HPRAE_RS07595
uniprot id: E3DNR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

572479:HPRAE RS10345
gene id: 572479:HPRAE_RS10345
uniprot id: E3DRS9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

572479:HPRAE RS01685
gene id: 572479:HPRAE_RS01685
uniprot id: E3DNE9
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS03835
gene id: 572479:HPRAE_RS03835
uniprot id: E3DQS7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

572479:HPRAE RS06310
gene id: 572479:HPRAE_RS06310
uniprot id: E3DMF8
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS10040
gene id: 572479:HPRAE_RS10040
uniprot id: E3DRF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

572479:HPRAE RS10065
gene id: 572479:HPRAE_RS10065
uniprot id: E3DRF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

572479:HPRAE RS06130
gene id: 572479:HPRAE_RS06130
uniprot id: E3DM52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

572479:HPRAE RS01260
gene id: 572479:HPRAE_RS01260
uniprot id: E3DMS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

572479:HPRAE RS02940
gene id: 572479:HPRAE_RS02940
uniprot id: E3DPR1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

572479:HPRAE RS09005
gene id: 572479:HPRAE_RS09005
uniprot id: E3DQ96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

572479:HPRAE RS10105
gene id: 572479:HPRAE_RS10105
uniprot id: E3DRG3
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS07325
gene id: 572479:HPRAE_RS07325
uniprot id: E3DNE1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

572479:HPRAE RS06105
gene id: 572479:HPRAE_RS06105
uniprot id: E3DM48
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

572479:HPRAE RS03330
gene id: 572479:HPRAE_RS03330
uniprot id: E3DQ56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

572479:HPRAE RS07160
gene id: 572479:HPRAE_RS07160
uniprot id: E3DNA8
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS09665
gene id: 572479:HPRAE_RS09665
uniprot id: E3DR18
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

572479:HPRAE RS03015
gene id: 572479:HPRAE_RS03015
uniprot id: E3DPS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

572479:HPRAE RS01165
gene id: 572479:HPRAE_RS01165
uniprot id: E3DMR0
names: Subcellular Location Annotation
messages: Membrane

572479:HPRAE RS09660
gene id: 572479:HPRAE_RS09660
uniprot id: E3DR17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

572479:HPRAE RS01185
gene id: 572479:HPRAE_RS01185
uniprot id: E3DMR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane