571913:VV02 RS06655
gene id: 571913:VV02_RS06655
uniprot id: A0A0K1JFX0
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS06955
gene id: 571913:VV02_RS06955
uniprot id: A0A0K1JG19
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS00305
gene id: 571913:VV02_RS00305
uniprot id: A0A0K1JD96
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

571913:VV02 RS15905
gene id: 571913:VV02_RS15905
uniprot id: A0A0K1JJX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

571913:VV02 RS12450
gene id: 571913:VV02_RS12450
uniprot id: A0A0K1JIE7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

571913:VV02 RS06035
gene id: 571913:VV02_RS06035
uniprot id: A0A0K1JFN0
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

571913:VV02 RS16140
gene id: 571913:VV02_RS16140
uniprot id: A0A0K1JK20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

571913:VV02 RS21220
gene id: 571913:VV02_RS21220
uniprot id: A0A0K1JMJ8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

571913:VV02 RS11510
gene id: 571913:VV02_RS11510
uniprot id: A0A0K1JI08
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M7 family.
messages: Binds 1 zinc ion per subunit.

571913:VV02 RS03905
gene id: 571913:VV02_RS03905
uniprot id: A0A0K1JEU3
names: Similarity
messages: Belongs to the TPP enzyme family.

571913:VV02 RS18085
gene id: 571913:VV02_RS18085
uniprot id: A0A0K1JR78
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS14985
gene id: 571913:VV02_RS14985
uniprot id: A0A0K1JJH1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

571913:VV02 RS17280
gene id: 571913:VV02_RS17280
uniprot id: A0A0K1JKI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

571913:VV02 RS00745
gene id: 571913:VV02_RS00745
uniprot id: A0A0K1JDH1
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS09140
gene id: 571913:VV02_RS09140
uniprot id: A0A0K1JHC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

571913:VV02 RS18935
gene id: 571913:VV02_RS18935
uniprot id: A0A0K1JLJ5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

571913:VV02 RS17840
gene id: 571913:VV02_RS17840
uniprot id: A0A0K1JQR2
names: Similarity
messages: Belongs to the ArsC family.

571913:VV02 RS21915
gene id: 571913:VV02_RS21915
uniprot id: A0A0K1JMG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

571913:VV02 RS07260
gene id: 571913:VV02_RS07260
uniprot id: A0A0K1JG80
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS01145
gene id: 571913:VV02_RS01145
uniprot id: A0A0K1JDL8
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS00710
gene id: 571913:VV02_RS00710
uniprot id: A0A0K1JDS9
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS13920
gene id: 571913:VV02_RS13920
uniprot id: A0A0K1JJG4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

571913:VV02 RS21525
gene id: 571913:VV02_RS21525
uniprot id: A0A0K1JMA8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

571913:VV02 RS05425
gene id: 571913:VV02_RS05425
uniprot id: A0A0K1JFF9
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS15720
gene id: 571913:VV02_RS15720
uniprot id: A0A0K1JQI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

571913:VV02 RS08585
gene id: 571913:VV02_RS08585
uniprot id: A0A0K1JQE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

571913:VV02 RS22045
gene id: 571913:VV02_RS22045
uniprot id: A0A0K1JMX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

571913:VV02 RS09765
gene id: 571913:VV02_RS09765
uniprot id: A0A0K1JHB3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

571913:VV02 RS25750
gene id: 571913:VV02_RS25750
uniprot id: A0A0K1JD53
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS02360
gene id: 571913:VV02_RS02360
uniprot id: A0A0K1JE39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

571913:VV02 RS19170
gene id: 571913:VV02_RS19170
uniprot id: A0A0K1JR75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

571913:VV02 RS10780
gene id: 571913:VV02_RS10780
uniprot id: A0A0K1JQ32
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

571913:VV02 RS13380
gene id: 571913:VV02_RS13380
uniprot id: A0A0K1JIV3
names: Similarity
messages: Belongs to the FemABX family.

571913:VV02 RS09880
gene id: 571913:VV02_RS09880
uniprot id: A0A0K1JHN4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

571913:VV02 RS12090
gene id: 571913:VV02_RS12090
uniprot id: A0A0K1JIB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

571913:VV02 RS15420
gene id: 571913:VV02_RS15420
uniprot id: A0A0K1JJM9
names: Subcellular Location Annotation
messages: Cytoplasm

571913:VV02 RS05435
gene id: 571913:VV02_RS05435
uniprot id: A0A0K1JFG7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

571913:VV02 RS04890
gene id: 571913:VV02_RS04890
uniprot id: A0A0K1JF84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS00775
gene id: 571913:VV02_RS00775
uniprot id: A0A0K1JDH6
names: Similarity
messages: Belongs to the peptidase S33 family.

571913:VV02 RS04355
gene id: 571913:VV02_RS04355
uniprot id: A0A0K1JFB4
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS18975
gene id: 571913:VV02_RS18975
uniprot id: A0A0K1JQV3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

571913:VV02 RS17070
gene id: 571913:VV02_RS17070
uniprot id: A0A0K1JKS6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

571913:VV02 RS08520
gene id: 571913:VV02_RS08520
uniprot id: A0A0K1JH36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

571913:VV02 RS21550
gene id: 571913:VV02_RS21550
uniprot id: A0A0K1JMA7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

571913:VV02 RS00280
gene id: 571913:VV02_RS00280
uniprot id: A0A0K1JD92
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS08590
gene id: 571913:VV02_RS08590
uniprot id: A0A0K1JGS3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

571913:VV02 RS08745
gene id: 571913:VV02_RS08745
uniprot id: A0A0K1JGT6
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS04305
gene id: 571913:VV02_RS04305
uniprot id: A0A0K1JPI5
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS03140
gene id: 571913:VV02_RS03140
uniprot id: A0A0K1JEH2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

571913:VV02 RS00120
gene id: 571913:VV02_RS00120
uniprot id: A0A0K1JD68
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS17215
gene id: 571913:VV02_RS17215
uniprot id: A0A0K1JKG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS10450
gene id: 571913:VV02_RS10450
uniprot id: A0A0K1JHK6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

571913:VV02 RS05335
gene id: 571913:VV02_RS05335
uniprot id: A0A0K1JFR1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

571913:VV02 RS11820
gene id: 571913:VV02_RS11820
uniprot id: A0A0K1JI54
names: Similarity
messages: Belongs to the UPF0102 family.

571913:VV02 RS11435
gene id: 571913:VV02_RS11435
uniprot id: A0A0K1JHZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

571913:VV02 RS11570
gene id: 571913:VV02_RS11570
uniprot id: A0A0K1JI17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

571913:VV02 RS21360
gene id: 571913:VV02_RS21360
uniprot id: A0A0K1JML7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

571913:VV02 RS11175
gene id: 571913:VV02_RS11175
uniprot id: A0A0K1JI98
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS19985
gene id: 571913:VV02_RS19985
uniprot id: A0A0K1JLY2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

571913:VV02 RS06045
gene id: 571913:VV02_RS06045
uniprot id: A0A0K1JFP4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

571913:VV02 RS14155
gene id: 571913:VV02_RS14155
uniprot id: A0A0K1JJK1
names: Similarity
messages: Belongs to the glutamate synthase family.

571913:VV02 RS15365
gene id: 571913:VV02_RS15365
uniprot id: A0A0K1JK18
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

571913:VV02 RS23300
gene id: 571913:VV02_RS23300
uniprot id: A0A0K1JRR1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

571913:VV02 RS01870
gene id: 571913:VV02_RS01870
uniprot id: A0A0K1JE89
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

571913:VV02 RS27250
gene id: 571913:VV02_RS27250
uniprot id: A0A0K1JRB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS20700
gene id: 571913:VV02_RS20700
uniprot id: A0A0K1JLX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

571913:VV02 RS19775
gene id: 571913:VV02_RS19775
uniprot id: A0A0K1JLH3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS14130
gene id: 571913:VV02_RS14130
uniprot id: A0A0K1JJJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

571913:VV02 RS23725
gene id: 571913:VV02_RS23725
uniprot id: A0A0K1JRQ3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

571913:VV02 RS17680
gene id: 571913:VV02_RS17680
uniprot id: A0A0K1JKN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS12125
gene id: 571913:VV02_RS12125
uniprot id: A0A0K1JIC0
names: Similarity
messages: Belongs to the glycosyl hydrolase.

571913:VV02 RS13585
gene id: 571913:VV02_RS13585
uniprot id: A0A0K1JJA4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

571913:VV02 RS22230
gene id: 571913:VV02_RS22230
uniprot id: A0A0K1JMK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

571913:VV02 RS15965
gene id: 571913:VV02_RS15965
uniprot id: A0A0K1JJY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

571913:VV02 RS12965
gene id: 571913:VV02_RS12965
uniprot id: A0A0K1JQA2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

571913:VV02 RS00225
gene id: 571913:VV02_RS00225
uniprot id: A0A0K1JD86
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

571913:VV02 RS03670
gene id: 571913:VV02_RS03670
uniprot id: A0A0K1JEP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS09110
gene id: 571913:VV02_RS09110
uniprot id: A0A0K1JHC4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

571913:VV02 RS20055
gene id: 571913:VV02_RS20055
uniprot id: A0A0K1JLZ3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

571913:VV02 RS11735
gene id: 571913:VV02_RS11735
uniprot id: A0A0K1JI41
names: Similarity
messages: Belongs to the serpin family.

571913:VV02 RS04400
gene id: 571913:VV02_RS04400
uniprot id: A0A0K1JPV7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

571913:VV02 RS16635
gene id: 571913:VV02_RS16635
uniprot id: A0A0K1JKK8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

571913:VV02 RS16015
gene id: 571913:VV02_RS16015
uniprot id: A0A0K1JJZ8
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

571913:VV02 RS06305
gene id: 571913:VV02_RS06305
uniprot id: A0A0K1JFT6
names: Similarity
messages: Belongs to the FPG family.

571913:VV02 RS12370
gene id: 571913:VV02_RS12370
uniprot id: A0A0K1JQ73
names: Similarity
messages: Belongs to the ribF family.

571913:VV02 RS13305
gene id: 571913:VV02_RS13305
uniprot id: A0A0K1JJ49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

571913:VV02 RS18290
gene id: 571913:VV02_RS18290
uniprot id: A0A0K1JKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

571913:VV02 RS15560
gene id: 571913:VV02_RS15560
uniprot id: A0A0K1JK48
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

571913:VV02 RS21400
gene id: 571913:VV02_RS21400
uniprot id: A0A0K1JMM8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

571913:VV02 RS20690
gene id: 571913:VV02_RS20690
uniprot id: A0A0K1JMA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS19835
gene id: 571913:VV02_RS19835
uniprot id: A0A0K1JLW3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

571913:VV02 RS25555
gene id: 571913:VV02_RS25555
uniprot id: A0A0K1JPF8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

571913:VV02 RS19710
gene id: 571913:VV02_RS19710
uniprot id: A0A0K1JLG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS04730
gene id: 571913:VV02_RS04730
uniprot id: A0A0K1JFI1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

571913:VV02 RS01285
gene id: 571913:VV02_RS01285
uniprot id: A0A0K1JDN0
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

571913:VV02 RS11040
gene id: 571913:VV02_RS11040
uniprot id: A0A0K1JHU7
names: Similarity
messages: Belongs to the CFA/CMAS family.

571913:VV02 RS10485
gene id: 571913:VV02_RS10485
uniprot id: A0A0K1JHZ7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

571913:VV02 RS13745
gene id: 571913:VV02_RS13745
uniprot id: A0A0K1JJC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

571913:VV02 RS20865
gene id: 571913:VV02_RS20865
uniprot id: A0A0K1JMD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

571913:VV02 RS12885
gene id: 571913:VV02_RS12885
uniprot id: A0A0K1JQ94
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

571913:VV02 RS14995
gene id: 571913:VV02_RS14995
uniprot id: A0A0K1JJJ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

571913:VV02 RS14930
gene id: 571913:VV02_RS14930
uniprot id: A0A0K1JJI7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

571913:VV02 RS09755
gene id: 571913:VV02_RS09755
uniprot id: A0A0K1JHA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

571913:VV02 RS14795
gene id: 571913:VV02_RS14795
uniprot id: A0A0K1JJE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

571913:VV02 RS19770
gene id: 571913:VV02_RS19770
uniprot id: A0A0K1JLV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

571913:VV02 RS12020
gene id: 571913:VV02_RS12020
uniprot id: A0A0K1JIM7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

571913:VV02 RS01450
gene id: 571913:VV02_RS01450
uniprot id: A0A0K1JDQ3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

571913:VV02 RS17800
gene id: 571913:VV02_RS17800
uniprot id: A0A0K1JKN9
names: Similarity
messages: Belongs to the CFA/CMAS family.

571913:VV02 RS16360
gene id: 571913:VV02_RS16360
uniprot id: A0A0K1JKG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

571913:VV02 RS07270
gene id: 571913:VV02_RS07270
uniprot id: A0A0K1JGJ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

571913:VV02 RS12275
gene id: 571913:VV02_RS12275
uniprot id: A0A0K1JIC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

571913:VV02 RS23040
gene id: 571913:VV02_RS23040
uniprot id: A0A0K1JMY4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

571913:VV02 RS18315
gene id: 571913:VV02_RS18315
uniprot id: A0A0K1JKW9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

571913:VV02 RS01265
gene id: 571913:VV02_RS01265
uniprot id: A0A0K1JE06
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS23570
gene id: 571913:VV02_RS23570
uniprot id: A0A0K1JNH7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

571913:VV02 RS21180
gene id: 571913:VV02_RS21180
uniprot id: A0A0K1JMI6
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

571913:VV02 RS13620
gene id: 571913:VV02_RS13620
uniprot id: A0A0K1JIZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

571913:VV02 RS10275
gene id: 571913:VV02_RS10275
uniprot id: A0A0K1JHI2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS03815
gene id: 571913:VV02_RS03815
uniprot id: A0A0K1JF41
names: Similarity
messages: Belongs to the asparaginase 1 family.

571913:VV02 RS13440
gene id: 571913:VV02_RS13440
uniprot id: A0A0K1JJ75
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

571913:VV02 RS14020
gene id: 571913:VV02_RS14020
uniprot id: A0A0K1JJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

571913:VV02 RS12400
gene id: 571913:VV02_RS12400
uniprot id: A0A0K1JIG0
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS25015
gene id: 571913:VV02_RS25015
uniprot id: A0A0K1JNR6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

571913:VV02 RS08125
gene id: 571913:VV02_RS08125
uniprot id: A0A0K1JGK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

571913:VV02 RS08135
gene id: 571913:VV02_RS08135
uniprot id: A0A0K1JGX9
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS22095
gene id: 571913:VV02_RS22095
uniprot id: A0A0K1JMI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS18675
gene id: 571913:VV02_RS18675
uniprot id: A0A0K1JLF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

571913:VV02 RS03945
gene id: 571913:VV02_RS03945
uniprot id: A0A0K1JF59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

571913:VV02 RS17825
gene id: 571913:VV02_RS17825
uniprot id: A0A0K1JKP4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

571913:VV02 RS08775
gene id: 571913:VV02_RS08775
uniprot id: A0A0K1JGU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

571913:VV02 RS07385
gene id: 571913:VV02_RS07385
uniprot id: A0A0K1JGM2
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

571913:VV02 RS02430
gene id: 571913:VV02_RS02430
uniprot id: A0A0K1JE58
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

571913:VV02 RS20740
gene id: 571913:VV02_RS20740
uniprot id: A0A0K1JLY5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

571913:VV02 RS17685
gene id: 571913:VV02_RS17685
uniprot id: A0A0K1JKN0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

571913:VV02 RS15415
gene id: 571913:VV02_RS15415
uniprot id: A0A0K1JK23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

571913:VV02 RS10290
gene id: 571913:VV02_RS10290
uniprot id: A0A0K1JHH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

571913:VV02 RS24090
gene id: 571913:VV02_RS24090
uniprot id: A0A0K1JNR8
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

571913:VV02 RS16645
gene id: 571913:VV02_RS16645
uniprot id: A0A0K1JK75
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS14445
gene id: 571913:VV02_RS14445
uniprot id: A0A0K1JJB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

571913:VV02 RS15430
gene id: 571913:VV02_RS15430
uniprot id: A0A0K1JJQ1
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS21285
gene id: 571913:VV02_RS21285
uniprot id: A0A0K1JM73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

571913:VV02 RS14125
gene id: 571913:VV02_RS14125
uniprot id: A0A0K1JJ68
names: Similarity
messages: Belongs to the TrpC family.

571913:VV02 RS21230
gene id: 571913:VV02_RS21230
uniprot id: A0A0K1JM63
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS17275
gene id: 571913:VV02_RS17275
uniprot id: A0A0K1JKX3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

571913:VV02 RS22300
gene id: 571913:VV02_RS22300
uniprot id: A0A0K1JMM5
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

571913:VV02 RS13995
gene id: 571913:VV02_RS13995
uniprot id: A0A0K1JJ47
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

571913:VV02 RS11905
gene id: 571913:VV02_RS11905
uniprot id: A0A0K1JIK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

571913:VV02 RS08640
gene id: 571913:VV02_RS08640
uniprot id: A0A0K1JH50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

571913:VV02 RS21475
gene id: 571913:VV02_RS21475
uniprot id: A0A0K1JMN4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

571913:VV02 RS09105
gene id: 571913:VV02_RS09105
uniprot id: A0A0K1JGZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS13370
gene id: 571913:VV02_RS13370
uniprot id: A0A0K1JQP3
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

571913:VV02 RS11910
gene id: 571913:VV02_RS11910
uniprot id: A0A0K1JI85
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

571913:VV02 RS15470
gene id: 571913:VV02_RS15470
uniprot id: A0A0K1JK33
names: Similarity
messages: Belongs to the ComB family.

571913:VV02 RS18455
gene id: 571913:VV02_RS18455
uniprot id: A0A0K1JQT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

571913:VV02 RS20195
gene id: 571913:VV02_RS20195
uniprot id: A0A0K1JRF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

571913:VV02 RS23220
gene id: 571913:VV02_RS23220
uniprot id: A0A0K1JN17
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

571913:VV02 RS16920
gene id: 571913:VV02_RS16920
uniprot id: A0A0K1JKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

571913:VV02 RS17315
gene id: 571913:VV02_RS17315
uniprot id: A0A0K1JKI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

571913:VV02 RS22155
gene id: 571913:VV02_RS22155
uniprot id: A0A0K1JMY6
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

571913:VV02 RS22765
gene id: 571913:VV02_RS22765
uniprot id: A0A0K1JN74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

571913:VV02 RS12445
gene id: 571913:VV02_RS12445
uniprot id: A0A0K1JIG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

571913:VV02 RS11530
gene id: 571913:VV02_RS11530
uniprot id: A0A0K1JIF1
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

571913:VV02 RS09745
gene id: 571913:VV02_RS09745
uniprot id: A0A0K1JPZ9
names: Similarity
messages: Belongs to the UPF0047 family.

571913:VV02 RS23190
gene id: 571913:VV02_RS23190
uniprot id: A0A0K1JND4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

571913:VV02 RS16875
gene id: 571913:VV02_RS16875
uniprot id: A0A0K1JK98
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

571913:VV02 RS15590
gene id: 571913:VV02_RS15590
uniprot id: A0A0K1JK54
names: Similarity
messages: Belongs to the glutamine synthetase family.

571913:VV02 RS04435
gene id: 571913:VV02_RS04435
uniprot id: A0A0K1JF16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS21200
gene id: 571913:VV02_RS21200
uniprot id: A0A0K1JR22
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

571913:VV02 RS24380
gene id: 571913:VV02_RS24380
uniprot id: A0A0K1JNV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

571913:VV02 RS02290
gene id: 571913:VV02_RS02290
uniprot id: A0A0K1JE38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

571913:VV02 RS15280
gene id: 571913:VV02_RS15280
uniprot id: A0A0K1JQZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS03825
gene id: 571913:VV02_RS03825
uniprot id: A0A0K1JES2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

571913:VV02 RS05085
gene id: 571913:VV02_RS05085
uniprot id: A0A0K1JFM6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

571913:VV02 RS21335
gene id: 571913:VV02_RS21335
uniprot id: A0A0K1JM79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

571913:VV02 RS12835
gene id: 571913:VV02_RS12835
uniprot id: A0A0K1JIM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

571913:VV02 RS08015
gene id: 571913:VV02_RS08015
uniprot id: A0A0K1JPW0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

571913:VV02 RS13445
gene id: 571913:VV02_RS13445
uniprot id: A0A0K1JIV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

571913:VV02 RS25400
gene id: 571913:VV02_RS25400
uniprot id: A0A0K1JNX9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS17080
gene id: 571913:VV02_RS17080
uniprot id: A0A0K1JKD9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

571913:VV02 RS03960
gene id: 571913:VV02_RS03960
uniprot id: A0A0K1JF70
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

571913:VV02 RS06560
gene id: 571913:VV02_RS06560
uniprot id: A0A0K1JG77
names: Similarity
messages: Belongs to the neutral ceramidase family.

571913:VV02 RS00125
gene id: 571913:VV02_RS00125
uniprot id: A0A0K1JDG1
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS20650
gene id: 571913:VV02_RS20650
uniprot id: A0A0K1JMA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

571913:VV02 RS08785
gene id: 571913:VV02_RS08785
uniprot id: A0A0K1JGU7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

571913:VV02 RS12595
gene id: 571913:VV02_RS12595
uniprot id: A0A0K1JIV6
names: Similarity
messages: Belongs to the FGGY kinase family.

571913:VV02 RS19060
gene id: 571913:VV02_RS19060
uniprot id: A0A0K1JL67
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

571913:VV02 RS21240
gene id: 571913:VV02_RS21240
uniprot id: A0A0K1JM66
names: Similarity
messages: Belongs to the CobH/CbiC family.

571913:VV02 RS12725
gene id: 571913:VV02_RS12725
uniprot id: A0A0K1JIX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

571913:VV02 RS04640
gene id: 571913:VV02_RS04640
uniprot id: A0A0K1JF26
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS19085
gene id: 571913:VV02_RS19085
uniprot id: A0A0K1JLL6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

571913:VV02 RS13570
gene id: 571913:VV02_RS13570
uniprot id: A0A0K1JIX8
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS17735
gene id: 571913:VV02_RS17735
uniprot id: A0A0K1JKP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

571913:VV02 RS07870
gene id: 571913:VV02_RS07870
uniprot id: A0A0K1JQB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

571913:VV02 RS24460
gene id: 571913:VV02_RS24460
uniprot id: A0A0K1JNJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

571913:VV02 RS22050
gene id: 571913:VV02_RS22050
uniprot id: A0A0K1JMJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

571913:VV02 RS15055
gene id: 571913:VV02_RS15055
uniprot id: A0A0K1JJI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

571913:VV02 RS19425
gene id: 571913:VV02_RS19425
uniprot id: A0A0K1JLR1
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS21980
gene id: 571913:VV02_RS21980
uniprot id: A0A0K1JMW7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

571913:VV02 RS02340
gene id: 571913:VV02_RS02340
uniprot id: A0A0K1JE47
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

571913:VV02 RS13860
gene id: 571913:VV02_RS13860
uniprot id: A0A0K1JJ21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

571913:VV02 RS11790
gene id: 571913:VV02_RS11790
uniprot id: A0A0K1JIJ2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

571913:VV02 RS10440
gene id: 571913:VV02_RS10440
uniprot id: A0A0K1JHX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS20705
gene id: 571913:VV02_RS20705
uniprot id: A0A0K1JMB2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

571913:VV02 RS03470
gene id: 571913:VV02_RS03470
uniprot id: A0A0K1JEX0
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS07205
gene id: 571913:VV02_RS07205
uniprot id: A0A0K1JGG6
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

571913:VV02 RS12570
gene id: 571913:VV02_RS12570
uniprot id: A0A0K1JIV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS15100
gene id: 571913:VV02_RS15100
uniprot id: A0A0K1JJY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

571913:VV02 RS11500
gene id: 571913:VV02_RS11500
uniprot id: A0A0K1JI20
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M7 family.
messages: Binds 1 zinc ion per subunit.

571913:VV02 RS11285
gene id: 571913:VV02_RS11285
uniprot id: A0A0K1JHY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

571913:VV02 RS00110
gene id: 571913:VV02_RS00110
uniprot id: A0A0K1JD49
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

571913:VV02 RS15030
gene id: 571913:VV02_RS15030
uniprot id: A0A0K1JJY6
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

571913:VV02 RS19265
gene id: 571913:VV02_RS19265
uniprot id: A0A0K1JLN6
names: Similarity
messages: Belongs to the UPF0045 family.

571913:VV02 RS20050
gene id: 571913:VV02_RS20050
uniprot id: A0A0K1JLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS09385
gene id: 571913:VV02_RS09385
uniprot id: A0A0K1JH52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

571913:VV02 RS21480
gene id: 571913:VV02_RS21480
uniprot id: A0A0K1JM97
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

571913:VV02 RS20685
gene id: 571913:VV02_RS20685
uniprot id: A0A0K1JLX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS21705
gene id: 571913:VV02_RS21705
uniprot id: A0A0K1JMD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

571913:VV02 RS12655
gene id: 571913:VV02_RS12655
uniprot id: A0A0K1JIW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS16755
gene id: 571913:VV02_RS16755
uniprot id: A0A0K1JKK9
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS19185
gene id: 571913:VV02_RS19185
uniprot id: A0A0K1JL90
names: Similarity
messages: Belongs to the phosphohexose mutase family.

571913:VV02 RS05770
gene id: 571913:VV02_RS05770
uniprot id: A0A0K1JFK9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

571913:VV02 RS20825
gene id: 571913:VV02_RS20825
uniprot id: A0A0K1JLZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

571913:VV02 RS21035
gene id: 571913:VV02_RS21035
uniprot id: A0A0K1JM37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

571913:VV02 RS14470
gene id: 571913:VV02_RS14470
uniprot id: A0A0K1JJQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

571913:VV02 RS19765
gene id: 571913:VV02_RS19765
uniprot id: A0A0K1JLH7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

571913:VV02 RS16135
gene id: 571913:VV02_RS16135
uniprot id: A0A0K1JKE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

571913:VV02 RS25250
gene id: 571913:VV02_RS25250
uniprot id: A0A0K1JP95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS12675
gene id: 571913:VV02_RS12675
uniprot id: A0A0K1JIJ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS20795
gene id: 571913:VV02_RS20795
uniprot id: A0A0K1JMC6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS02385
gene id: 571913:VV02_RS02385
uniprot id: A0A0K1JPC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

571913:VV02 RS19360
gene id: 571913:VV02_RS19360
uniprot id: A0A0K1JLA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

571913:VV02 RS10950
gene id: 571913:VV02_RS10950
uniprot id: A0A0K1JQ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

571913:VV02 RS19555
gene id: 571913:VV02_RS19555
uniprot id: A0A0K1JLE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

571913:VV02 RS03595
gene id: 571913:VV02_RS03595
uniprot id: A0A0K1JEN5
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS07955
gene id: 571913:VV02_RS07955
uniprot id: A0A0K1JGV5
names: Similarity
messages: Belongs to the universal stress protein A family.

571913:VV02 RS07885
gene id: 571913:VV02_RS07885
uniprot id: A0A0K1JGH1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

571913:VV02 RS03145
gene id: 571913:VV02_RS03145
uniprot id: A0A0K1JER8
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS04440
gene id: 571913:VV02_RS04440
uniprot id: A0A0K1JEZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS20815
gene id: 571913:VV02_RS20815
uniprot id: A0A0K1JLZ7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

571913:VV02 RS22020
gene id: 571913:VV02_RS22020
uniprot id: A0A0K1JMH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

571913:VV02 RS01085
gene id: 571913:VV02_RS01085
uniprot id: A0A0K1JDY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

571913:VV02 RS13345
gene id: 571913:VV02_RS13345
uniprot id: A0A0K1JIU8
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

571913:VV02 RS19790
gene id: 571913:VV02_RS19790
uniprot id: A0A0K1JLI6
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS08805
gene id: 571913:VV02_RS08805
uniprot id: A0A0K1JGU5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

571913:VV02 RS01400
gene id: 571913:VV02_RS01400
uniprot id: A0A0K1JDQ6
names: Similarity
messages: Belongs to the peptidase C1 family.

571913:VV02 RS19050
gene id: 571913:VV02_RS19050
uniprot id: A0A0K1JLL1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

571913:VV02 RS14735
gene id: 571913:VV02_RS14735
uniprot id: A0A0K1JJE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS12915
gene id: 571913:VV02_RS12915
uniprot id: A0A0K1JIL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

571913:VV02 RS00595
gene id: 571913:VV02_RS00595
uniprot id: A0A0K1JDQ7
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

571913:VV02 RS24930
gene id: 571913:VV02_RS24930
uniprot id: A0A0K1JNQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

571913:VV02 RS24245
gene id: 571913:VV02_RS24245
uniprot id: A0A0K1JNG2
names: Similarity
messages: Belongs to the AHA1 family.

571913:VV02 RS10030
gene id: 571913:VV02_RS10030
uniprot id: A0A0K1JHR1
names: Similarity
messages: Belongs to the peptidase C40 family.

571913:VV02 RS25110
gene id: 571913:VV02_RS25110
uniprot id: A0A0K1JP61
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

571913:VV02 RS22700
gene id: 571913:VV02_RS22700
uniprot id: A0A0K1JMT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

571913:VV02 RS06420
gene id: 571913:VV02_RS06420
uniprot id: A0A0K1JG59
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

571913:VV02 RS18400
gene id: 571913:VV02_RS18400
uniprot id: A0A0K1JQT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

571913:VV02 RS10735
gene id: 571913:VV02_RS10735
uniprot id: A0A0K1JI31
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

571913:VV02 RS10005
gene id: 571913:VV02_RS10005
uniprot id: A0A0K1JHE2
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS19635
gene id: 571913:VV02_RS19635
uniprot id: A0A0K1JLU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

571913:VV02 RS21685
gene id: 571913:VV02_RS21685
uniprot id: A0A0K1JMC5
names: Similarity
messages: Belongs to the peptidase M1 family.

571913:VV02 RS22815
gene id: 571913:VV02_RS22815
uniprot id: A0A0K1JMW1
names: Subcellular Location Annotation
messages: Mitochondrion

571913:VV02 RS25390
gene id: 571913:VV02_RS25390
uniprot id: A0A0K1JNX1
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

571913:VV02 RS05540
gene id: 571913:VV02_RS05540
uniprot id: A0A0K1JFH9
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS26830
gene id: 571913:VV02_RS26830
uniprot id: A0A0K1JJ00
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

571913:VV02 RS15730
gene id: 571913:VV02_RS15730
uniprot id: A0A0K1JJU8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

571913:VV02 RS21990
gene id: 571913:VV02_RS21990
uniprot id: A0A0K1JMH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

571913:VV02 RS09290
gene id: 571913:VV02_RS09290
uniprot id: A0A0K1JH38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

571913:VV02 RS15835
gene id: 571913:VV02_RS15835
uniprot id: A0A0K1JK85
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

571913:VV02 RS15065
gene id: 571913:VV02_RS15065
uniprot id: A0A0K1JJK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

571913:VV02 RS09175
gene id: 571913:VV02_RS09175
uniprot id: A0A0K1JHD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS04320
gene id: 571913:VV02_RS04320
uniprot id: A0A0K1JFA9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

571913:VV02 RS14670
gene id: 571913:VV02_RS14670
uniprot id: A0A0K1JJS5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

571913:VV02 RS01115
gene id: 571913:VV02_RS01115
uniprot id: A0A0K1JDY0
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

571913:VV02 RS09895
gene id: 571913:VV02_RS09895
uniprot id: A0A0K1JHD3
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

571913:VV02 RS24800
gene id: 571913:VV02_RS24800
uniprot id: A0A0K1JP29
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

571913:VV02 RS02020
gene id: 571913:VV02_RS02020
uniprot id: A0A0K1JEB3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

571913:VV02 RS09260
gene id: 571913:VV02_RS09260
uniprot id: A0A0K1JHE5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

571913:VV02 RS04690
gene id: 571913:VV02_RS04690
uniprot id: A0A0K1JFG0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

571913:VV02 RS18525
gene id: 571913:VV02_RS18525
uniprot id: A0A0K1JL01
names: Similarity
messages: Belongs to the disproportionating enzyme family.

571913:VV02 RS09670
gene id: 571913:VV02_RS09670
uniprot id: A0A0K1JH98
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS14770
gene id: 571913:VV02_RS14770
uniprot id: A0A0K1JJV1
names: Similarity
messages: Belongs to the IucA/IucC family.

571913:VV02 RS14510
gene id: 571913:VV02_RS14510
uniprot id: A0A0K1JJD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

571913:VV02 RS14570
gene id: 571913:VV02_RS14570
uniprot id: A0A0K1JJR0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

571913:VV02 RS26775
gene id: 571913:VV02_RS26775
uniprot id: A0A0K1JDX4
names: Similarity
messages: Belongs to the FPG family.

571913:VV02 RS06935
gene id: 571913:VV02_RS06935
uniprot id: A0A0K1JGD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS12035
gene id: 571913:VV02_RS12035
uniprot id: A0A0K1JI88
names: Similarity
messages: Belongs to the CutC family.

571913:VV02 RS18895
gene id: 571913:VV02_RS18895
uniprot id: A0A0K1JLJ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS13420
gene id: 571913:VV02_RS13420
uniprot id: A0A0K1JIU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

571913:VV02 RS10860
gene id: 571913:VV02_RS10860
uniprot id: A0A0K1JI52
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS06815
gene id: 571913:VV02_RS06815
uniprot id: A0A0K1JFZ0
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

571913:VV02 RS23390
gene id: 571913:VV02_RS23390
uniprot id: A0A0K1JN50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

571913:VV02 RS13650
gene id: 571913:VV02_RS13650
uniprot id: A0A0K1JIZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS14555
gene id: 571913:VV02_RS14555
uniprot id: A0A0K1JJR8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

571913:VV02 RS10095
gene id: 571913:VV02_RS10095
uniprot id: A0A0K1JHS1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

571913:VV02 RS08355
gene id: 571913:VV02_RS08355
uniprot id: A0A0K1JH07
names: Similarity
messages: Belongs to the UDPGP type 2 family.

571913:VV02 RS05780
gene id: 571913:VV02_RS05780
uniprot id: A0A0K1JFL7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

571913:VV02 RS16350
gene id: 571913:VV02_RS16350
uniprot id: A0A0K1JQK1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

571913:VV02 RS09520
gene id: 571913:VV02_RS09520
uniprot id: A0A0K1JH58
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS24340
gene id: 571913:VV02_RS24340
uniprot id: A0A0K1JNH9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

571913:VV02 RS13865
gene id: 571913:VV02_RS13865
uniprot id: A0A0K1JQQ8
names: Similarity
messages: Belongs to the glutamate synthase family.

571913:VV02 RS16490
gene id: 571913:VV02_RS16490
uniprot id: A0A0K1JK47
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS11590
gene id: 571913:VV02_RS11590
uniprot id: A0A0K1JI23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

571913:VV02 RS16190
gene id: 571913:VV02_RS16190
uniprot id: A0A0K1JK12
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

571913:VV02 RS16225
gene id: 571913:VV02_RS16225
uniprot id: A0A0K1JK11
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

571913:VV02 RS15820
gene id: 571913:VV02_RS15820
uniprot id: A0A0K1JK91
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS25310
gene id: 571913:VV02_RS25310
uniprot id: A0A0K1JNW4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

571913:VV02 RS13390
gene id: 571913:VV02_RS13390
uniprot id: A0A0K1JJ65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

571913:VV02 RS11650
gene id: 571913:VV02_RS11650
uniprot id: A0A0K1JI33
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

571913:VV02 RS01715
gene id: 571913:VV02_RS01715
uniprot id: A0A0K1JE71
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS14465
gene id: 571913:VV02_RS14465
uniprot id: A0A0K1JJB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

571913:VV02 RS18360
gene id: 571913:VV02_RS18360
uniprot id: A0A0K1JLB8
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

571913:VV02 RS05300
gene id: 571913:VV02_RS05300
uniprot id: A0A0K1JFE5
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

571913:VV02 RS18160
gene id: 571913:VV02_RS18160
uniprot id: A0A0K1JL93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

571913:VV02 RS09255
gene id: 571913:VV02_RS09255
uniprot id: A0A0K1JH19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

571913:VV02 RS03980
gene id: 571913:VV02_RS03980
uniprot id: A0A0K1JEU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

571913:VV02 RS24550
gene id: 571913:VV02_RS24550
uniprot id: A0A0K1JNX7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

571913:VV02 RS18875
gene id: 571913:VV02_RS18875
uniprot id: A0A0K1JL34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

571913:VV02 RS18625
gene id: 571913:VV02_RS18625
uniprot id: A0A0K1JL05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

571913:VV02 RS21090
gene id: 571913:VV02_RS21090
uniprot id: A0A0K1JRE8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

571913:VV02 RS00315
gene id: 571913:VV02_RS00315
uniprot id: A0A0K1JD97
names: Similarity
messages: Belongs to the pirin family.

571913:VV02 RS23370
gene id: 571913:VV02_RS23370
uniprot id: A0A0K1JNF2
names: Similarity
messages: Belongs to the GSP E family.

571913:VV02 RS21725
gene id: 571913:VV02_RS21725
uniprot id: A0A0K1JMS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

571913:VV02 RS08320
gene id: 571913:VV02_RS08320
uniprot id: A0A0K1JH02
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS01420
gene id: 571913:VV02_RS01420
uniprot id: A0A0K1JE25
names: Similarity
messages: Belongs to the peptidase M1 family.

571913:VV02 RS01205
gene id: 571913:VV02_RS01205
uniprot id: A0A0K1JDM8
names: Similarity
messages: Belongs to the peptidase S33 family.

571913:VV02 RS13230
gene id: 571913:VV02_RS13230
uniprot id: A0A0K1JIT1
names: Similarity
messages: Belongs to the CdaR family.

571913:VV02 RS09535
gene id: 571913:VV02_RS09535
uniprot id: A0A0K1JQC5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

571913:VV02 RS02235
gene id: 571913:VV02_RS02235
uniprot id: A0A0K1JE33
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS17625
gene id: 571913:VV02_RS17625
uniprot id: A0A0K1JKM1
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS12825
gene id: 571913:VV02_RS12825
uniprot id: A0A0K1JIK3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

571913:VV02 RS13705
gene id: 571913:VV02_RS13705
uniprot id: A0A0K1JQB2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

571913:VV02 RS18500
gene id: 571913:VV02_RS18500
uniprot id: A0A0K1JKY6
names: Similarity
messages: Belongs to the peptidase M1 family.

571913:VV02 RS14475
gene id: 571913:VV02_RS14475
uniprot id: A0A0K1JJC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

571913:VV02 RS24140
gene id: 571913:VV02_RS24140
uniprot id: A0A0K1JNG4
names: Similarity
messages: Belongs to the IucA/IucC family.

571913:VV02 RS18680
gene id: 571913:VV02_RS18680
uniprot id: A0A0K1JL21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

571913:VV02 RS19615
gene id: 571913:VV02_RS19615
uniprot id: A0A0K1JLF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS14230
gene id: 571913:VV02_RS14230
uniprot id: A0A0K1JJ78
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

571913:VV02 RS20960
gene id: 571913:VV02_RS20960
uniprot id: A0A0K1JM23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

571913:VV02 RS12890
gene id: 571913:VV02_RS12890
uniprot id: A0A0K1JQN3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

571913:VV02 RS08930
gene id: 571913:VV02_RS08930
uniprot id: A0A0K1JH95
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

571913:VV02 RS02395
gene id: 571913:VV02_RS02395
uniprot id: A0A0K1JPD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

571913:VV02 RS13210
gene id: 571913:VV02_RS13210
uniprot id: A0A0K1JIR5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

571913:VV02 RS12240
gene id: 571913:VV02_RS12240
uniprot id: A0A0K1JIR4
names: Subcellular Location Annotation
messages: cytosol

571913:VV02 RS19380
gene id: 571913:VV02_RS19380
uniprot id: A0A0K1JLB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

571913:VV02 RS11760
gene id: 571913:VV02_RS11760
uniprot id: A0A0K1JI46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

571913:VV02 RS19655
gene id: 571913:VV02_RS19655
uniprot id: A0A0K1JLF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

571913:VV02 RS06300
gene id: 571913:VV02_RS06300
uniprot id: A0A0K1JG52
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS18845
gene id: 571913:VV02_RS18845
uniprot id: A0A0K1JLI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

571913:VV02 RS09845
gene id: 571913:VV02_RS09845
uniprot id: A0A0K1JHB7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

571913:VV02 RS12045
gene id: 571913:VV02_RS12045
uniprot id: A0A0K1JIM8
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

571913:VV02 RS06115
gene id: 571913:VV02_RS06115
uniprot id: A0A0K1JG18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS15580
gene id: 571913:VV02_RS15580
uniprot id: A0A0K1JJR7
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS15980
gene id: 571913:VV02_RS15980
uniprot id: A0A0K1JJW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

571913:VV02 RS00060
gene id: 571913:VV02_RS00060
uniprot id: A0A0K1JDE7
names: Similarity
messages: Belongs to the AHA1 family.

571913:VV02 RS02525
gene id: 571913:VV02_RS02525
uniprot id: A0A0K1JPQ5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

571913:VV02 RS02280
gene id: 571913:VV02_RS02280
uniprot id: A0A0K1JEF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS03065
gene id: 571913:VV02_RS03065
uniprot id: A0A0K1JEE6
names: Similarity
messages: Belongs to the peptidase S51 family.

571913:VV02 RS14455
gene id: 571913:VV02_RS14455
uniprot id: A0A0K1JQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

571913:VV02 RS16740
gene id: 571913:VV02_RS16740
uniprot id: A0A0K1JK87
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

571913:VV02 RS20980
gene id: 571913:VV02_RS20980
uniprot id: A0A0K1JMF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

571913:VV02 RS23070
gene id: 571913:VV02_RS23070
uniprot id: A0A0K1JRM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

571913:VV02 RS04775
gene id: 571913:VV02_RS04775
uniprot id: A0A0K1JF44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

571913:VV02 RS18080
gene id: 571913:VV02_RS18080
uniprot id: A0A0K1JQS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

571913:VV02 RS17405
gene id: 571913:VV02_RS17405
uniprot id: A0A0K1JKJ1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

571913:VV02 RS15095
gene id: 571913:VV02_RS15095
uniprot id: A0A0K1JJK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

571913:VV02 RS21520
gene id: 571913:VV02_RS21520
uniprot id: A0A0K1JMP8
names: Similarity
messages: Belongs to the UPF0336 family.

571913:VV02 RS04625
gene id: 571913:VV02_RS04625
uniprot id: A0A0K1JFF0
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS07215
gene id: 571913:VV02_RS07215
uniprot id: A0A0K1JG68
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS16925
gene id: 571913:VV02_RS16925
uniprot id: A0A0K1JKN7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

571913:VV02 RS06585
gene id: 571913:VV02_RS06585
uniprot id: A0A0K1JG82
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

571913:VV02 RS14635
gene id: 571913:VV02_RS14635
uniprot id: A0A0K1JJS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

571913:VV02 RS24850
gene id: 571913:VV02_RS24850
uniprot id: A0A0K1JNN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS03570
gene id: 571913:VV02_RS03570
uniprot id: A0A0K1JEY0
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

571913:VV02 RS00170
gene id: 571913:VV02_RS00170
uniprot id: A0A0K1JDG6
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

571913:VV02 RS25410
gene id: 571913:VV02_RS25410
uniprot id: A0A0K1JPB1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

571913:VV02 RS14375
gene id: 571913:VV02_RS14375
uniprot id: A0A0K1JJP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

571913:VV02 RS21065
gene id: 571913:VV02_RS21065
uniprot id: A0A0K1JM40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

571913:VV02 RS16640
gene id: 571913:VV02_RS16640
uniprot id: A0A0K1JK92
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

571913:VV02 RS01470
gene id: 571913:VV02_RS01470
uniprot id: A0A0K1JE36
names: Similarity
messages: Belongs to the Nudix hydrolase family.

571913:VV02 RS13055
gene id: 571913:VV02_RS13055
uniprot id: A0A0K1JJ11
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

571913:VV02 RS25550
gene id: 571913:VV02_RS25550
uniprot id: A0A0K1JP02
names: Similarity
messages: Belongs to the ABC transporter superfamily.

571913:VV02 RS21720
gene id: 571913:VV02_RS21720
uniprot id: A0A0K1JMD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

571913:VV02 RS23740
gene id: 571913:VV02_RS23740
uniprot id: A0A0K1JN76
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS13520
gene id: 571913:VV02_RS13520
uniprot id: A0A0K1JJ94
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

571913:VV02 RS24520
gene id: 571913:VV02_RS24520
uniprot id: A0A0K1JNX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

571913:VV02 RS08630
gene id: 571913:VV02_RS08630
uniprot id: A0A0K1JH49
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS19350
gene id: 571913:VV02_RS19350
uniprot id: A0A0K1JLA9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

571913:VV02 RS20910
gene id: 571913:VV02_RS20910
uniprot id: A0A0K1JME4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

571913:VV02 RS14710
gene id: 571913:VV02_RS14710
uniprot id: A0A0K1JJD8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

571913:VV02 RS22635
gene id: 571913:VV02_RS22635
uniprot id: A0A0K1JMS3
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS15090
gene id: 571913:VV02_RS15090
uniprot id: A0A0K1JJL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

571913:VV02 RS07200
gene id: 571913:VV02_RS07200
uniprot id: A0A0K1JG60
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

571913:VV02 RS20925
gene id: 571913:VV02_RS20925
uniprot id: A0A0K1JM18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

571913:VV02 RS00095
gene id: 571913:VV02_RS00095
uniprot id: A0A0K1JD63
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS11565
gene id: 571913:VV02_RS11565
uniprot id: A0A0K1JI32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

571913:VV02 RS13010
gene id: 571913:VV02_RS13010
uniprot id: A0A0K1JJ10
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS11640
gene id: 571913:VV02_RS11640
uniprot id: A0A0K1JI29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS25020
gene id: 571913:VV02_RS25020
uniprot id: A0A0K1JP51
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS09595
gene id: 571913:VV02_RS09595
uniprot id: A0A0K1JH80
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

571913:VV02 RS09620
gene id: 571913:VV02_RS09620
uniprot id: A0A0K1JH88
names: Subcellular Location Annotation
messages: Secreted

571913:VV02 RS13530
gene id: 571913:VV02_RS13530
uniprot id: A0A0K1JIX3
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

571913:VV02 RS17455
gene id: 571913:VV02_RS17455
uniprot id: A0A0K1JKJ2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

571913:VV02 RS17360
gene id: 571913:VV02_RS17360
uniprot id: A0A0K1JKI6
names: Similarity
messages: Belongs to the universal stress protein A family.

571913:VV02 RS21950
gene id: 571913:VV02_RS21950
uniprot id: A0A0K1JMH5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS10745
gene id: 571913:VV02_RS10745
uniprot id: A0A0K1JQK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

571913:VV02 RS11460
gene id: 571913:VV02_RS11460
uniprot id: A0A0K1JI01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

571913:VV02 RS07275
gene id: 571913:VV02_RS07275
uniprot id: A0A0K1JG85
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS13485
gene id: 571913:VV02_RS13485
uniprot id: A0A0K1JQA8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

571913:VV02 RS10660
gene id: 571913:VV02_RS10660
uniprot id: A0A0K1JQG0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

571913:VV02 RS25620
gene id: 571913:VV02_RS25620
uniprot id: A0A0K1JRH3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

571913:VV02 RS18305
gene id: 571913:VV02_RS18305
uniprot id: A0A0K1JKV3
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

571913:VV02 RS15205
gene id: 571913:VV02_RS15205
uniprot id: A0A0K1JK09
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

571913:VV02 RS20665
gene id: 571913:VV02_RS20665
uniprot id: A0A0K1JMA4
names: Similarity
messages: Belongs to the FBPase class 2 family.

571913:VV02 RS18955
gene id: 571913:VV02_RS18955
uniprot id: A0A0K1JL60
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS13170
gene id: 571913:VV02_RS13170
uniprot id: A0A0K1JJ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS10670
gene id: 571913:VV02_RS10670
uniprot id: A0A0K1JHN9
names: Similarity
messages: Belongs to the PGI/PMI family.

571913:VV02 RS24905
gene id: 571913:VV02_RS24905
uniprot id: A0A0K1JNP8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

571913:VV02 RS15015
gene id: 571913:VV02_RS15015
uniprot id: A0A0K1JJH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

571913:VV02 RS21010
gene id: 571913:VV02_RS21010
uniprot id: A0A0K1JM33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

571913:VV02 RS18075
gene id: 571913:VV02_RS18075
uniprot id: A0A0K1JKT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

571913:VV02 RS06340
gene id: 571913:VV02_RS06340
uniprot id: A0A0K1JFU2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

571913:VV02 RS24645
gene id: 571913:VV02_RS24645
uniprot id: A0A0K1JNM2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

571913:VV02 RS17645
gene id: 571913:VV02_RS17645
uniprot id: A0A0K1JL19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

571913:VV02 RS21710
gene id: 571913:VV02_RS21710
uniprot id: A0A0K1JMD0
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS14955
gene id: 571913:VV02_RS14955
uniprot id: A0A0K1JJX6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS01360
gene id: 571913:VV02_RS01360
uniprot id: A0A0K1JDP9
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

571913:VV02 RS11545
gene id: 571913:VV02_RS11545
uniprot id: A0A0K1JIF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

571913:VV02 RS20330
gene id: 571913:VV02_RS20330
uniprot id: A0A0K1JLQ5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS15785
gene id: 571913:VV02_RS15785
uniprot id: A0A0K1JJT4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

571913:VV02 RS14890
gene id: 571913:VV02_RS14890
uniprot id: A0A0K1JJI2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

571913:VV02 RS09640
gene id: 571913:VV02_RS09640
uniprot id: A0A0K1JHK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS07910
gene id: 571913:VV02_RS07910
uniprot id: A0A0K1JGG8
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS19665
gene id: 571913:VV02_RS19665
uniprot id: A0A0K1JLG6
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS15070
gene id: 571913:VV02_RS15070
uniprot id: A0A0K1JJJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

571913:VV02 RS19095
gene id: 571913:VV02_RS19095
uniprot id: A0A0K1JL72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS22180
gene id: 571913:VV02_RS22180
uniprot id: A0A0K1JML0
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

571913:VV02 RS16735
gene id: 571913:VV02_RS16735
uniprot id: A0A0K1JKA2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

571913:VV02 RS03940
gene id: 571913:VV02_RS03940
uniprot id: A0A0K1JEU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

571913:VV02 RS09070
gene id: 571913:VV02_RS09070
uniprot id: A0A0K1JHB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS11875
gene id: 571913:VV02_RS11875
uniprot id: A0A0K1JIK1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

571913:VV02 RS09035
gene id: 571913:VV02_RS09035
uniprot id: A0A0K1JHB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

571913:VV02 RS02990
gene id: 571913:VV02_RS02990
uniprot id: A0A0K1JED1
names: Similarity
messages: Belongs to the AHA1 family.

571913:VV02 RS25585
gene id: 571913:VV02_RS25585
uniprot id: A0A0K1JP16
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

571913:VV02 RS13265
gene id: 571913:VV02_RS13265
uniprot id: A0A0K1JIS5
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

571913:VV02 RS24185
gene id: 571913:VV02_RS24185
uniprot id: A0A0K1JNF8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

571913:VV02 RS14760
gene id: 571913:VV02_RS14760
uniprot id: A0A0K1JJE4
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

571913:VV02 RS22005
gene id: 571913:VV02_RS22005
uniprot id: A0A0K1JMI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

571913:VV02 RS06095
gene id: 571913:VV02_RS06095
uniprot id: A0A0K1JFQ9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

571913:VV02 RS21125
gene id: 571913:VV02_RS21125
uniprot id: A0A0K1JM48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

571913:VV02 RS05685
gene id: 571913:VV02_RS05685
uniprot id: A0A0K1JFX1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

571913:VV02 RS07310
gene id: 571913:VV02_RS07310
uniprot id: A0A0K1JG78
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

571913:VV02 RS04310
gene id: 571913:VV02_RS04310
uniprot id: A0A0K1JFB8
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS26730
gene id: 571913:VV02_RS26730
uniprot id: A0A0K1JMQ8
names: Similarity
messages: Belongs to the AHA1 family.

571913:VV02 RS15390
gene id: 571913:VV02_RS15390
uniprot id: A0A0K1JK30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

571913:VV02 RS02460
gene id: 571913:VV02_RS02460
uniprot id: A0A0K1JE63
names: Similarity
messages: Belongs to the Nudix hydrolase family.

571913:VV02 RS17120
gene id: 571913:VV02_RS17120
uniprot id: A0A0K1JKE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

571913:VV02 RS08365
gene id: 571913:VV02_RS08365
uniprot id: A0A0K1JGM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

571913:VV02 RS20775
gene id: 571913:VV02_RS20775
uniprot id: A0A0K1JLZ0
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS11825
gene id: 571913:VV02_RS11825
uniprot id: A0A0K1JIJ7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

571913:VV02 RS06180
gene id: 571913:VV02_RS06180
uniprot id: A0A0K1JFR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

571913:VV02 RS20950
gene id: 571913:VV02_RS20950
uniprot id: A0A0K1JM19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

571913:VV02 RS20345
gene id: 571913:VV02_RS20345
uniprot id: A0A0K1JLR9
names: Similarity
messages: Belongs to the peptidase S51 family.

571913:VV02 RS06910
gene id: 571913:VV02_RS06910
uniprot id: A0A0K1JGD2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

571913:VV02 RS05380
gene id: 571913:VV02_RS05380
uniprot id: A0A0K1JFF6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

571913:VV02 RS13780
gene id: 571913:VV02_RS13780
uniprot id: A0A0K1JJ13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS24015
gene id: 571913:VV02_RS24015
uniprot id: A0A0K1JNS2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

571913:VV02 RS12075
gene id: 571913:VV02_RS12075
uniprot id: A0A0K1JI97
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS17260
gene id: 571913:VV02_RS17260
uniprot id: A0A0K1JKH3
names: Similarity
messages: Belongs to the YggT family.

571913:VV02 RS24975
gene id: 571913:VV02_RS24975
uniprot id: A0A0K1JP58
names: Similarity
messages: Belongs to the YoeB family.

571913:VV02 RS07810
gene id: 571913:VV02_RS07810
uniprot id: A0A0K1JGT5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

571913:VV02 RS15295
gene id: 571913:VV02_RS15295
uniprot id: A0A0K1JJL4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

571913:VV02 RS18460
gene id: 571913:VV02_RS18460
uniprot id: A0A0K1JLD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

571913:VV02 RS03380
gene id: 571913:VV02_RS03380
uniprot id: A0A0K1JEJ7
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.

571913:VV02 RS08995
gene id: 571913:VV02_RS08995
uniprot id: A0A0K1JGX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

571913:VV02 RS21410
gene id: 571913:VV02_RS21410
uniprot id: A0A0K1JM89
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

571913:VV02 RS07135
gene id: 571913:VV02_RS07135
uniprot id: A0A0K1JG53
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.

571913:VV02 RS12865
gene id: 571913:VV02_RS12865
uniprot id: A0A0K1JIM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

571913:VV02 RS23240
gene id: 571913:VV02_RS23240
uniprot id: A0A0K1JN28
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS16805
gene id: 571913:VV02_RS16805
uniprot id: A0A0K1JKL4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

571913:VV02 RS11520
gene id: 571913:VV02_RS11520
uniprot id: A0A0K1JI13
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

571913:VV02 RS08540
gene id: 571913:VV02_RS08540
uniprot id: A0A0K1JGR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

571913:VV02 RS25565
gene id: 571913:VV02_RS25565
uniprot id: A0A0K1JP08
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

571913:VV02 RS21790
gene id: 571913:VV02_RS21790
uniprot id: A0A0K1JMT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

571913:VV02 RS15200
gene id: 571913:VV02_RS15200
uniprot id: A0A0K1JJK4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

571913:VV02 RS08110
gene id: 571913:VV02_RS08110
uniprot id: A0A0K1JGJ4
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

571913:VV02 RS24100
gene id: 571913:VV02_RS24100
uniprot id: A0A0K1JRR3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS23685
gene id: 571913:VV02_RS23685
uniprot id: A0A0K1JN72
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS15570
gene id: 571913:VV02_RS15570
uniprot id: A0A0K1JK59
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS22390
gene id: 571913:VV02_RS22390
uniprot id: A0A0K1JRN0
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS09970
gene id: 571913:VV02_RS09970
uniprot id: A0A0K1JHD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

571913:VV02 RS01160
gene id: 571913:VV02_RS01160
uniprot id: A0A0K1JDM5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS03035
gene id: 571913:VV02_RS03035
uniprot id: A0A0K1JEF1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

571913:VV02 RS17665
gene id: 571913:VV02_RS17665
uniprot id: A0A0K1JKM0
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS21055
gene id: 571913:VV02_RS21055
uniprot id: A0A0K1JMH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

571913:VV02 RS05830
gene id: 571913:VV02_RS05830
uniprot id: A0A0K1JFZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

571913:VV02 RS19795
gene id: 571913:VV02_RS19795
uniprot id: A0A0K1JLI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

571913:VV02 RS20335
gene id: 571913:VV02_RS20335
uniprot id: A0A0K1JM38
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

571913:VV02 RS00290
gene id: 571913:VV02_RS00290
uniprot id: A0A0K1JP52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

571913:VV02 RS22600
gene id: 571913:VV02_RS22600
uniprot id: A0A0K1JN49
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

571913:VV02 RS05905
gene id: 571913:VV02_RS05905
uniprot id: A0A0K1JFY8
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

571913:VV02 RS04215
gene id: 571913:VV02_RS04215
uniprot id: A0A0K1JFA5
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS07710
gene id: 571913:VV02_RS07710
uniprot id: A0A0K1JGE6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

571913:VV02 RS21310
gene id: 571913:VV02_RS21310
uniprot id: A0A0K1JM80
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

571913:VV02 RS12015
gene id: 571913:VV02_RS12015
uniprot id: A0A0K1JI87
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

571913:VV02 RS12880
gene id: 571913:VV02_RS12880
uniprot id: A0A0K1JIL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

571913:VV02 RS21420
gene id: 571913:VV02_RS21420
uniprot id: A0A0K1JM91
names: Similarity
messages: Belongs to the TelA family.

571913:VV02 RS22160
gene id: 571913:VV02_RS22160
uniprot id: A0A0K1JMK6
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

571913:VV02 RS04165
gene id: 571913:VV02_RS04165
uniprot id: A0A0K1JEX9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

571913:VV02 RS12760
gene id: 571913:VV02_RS12760
uniprot id: A0A0K1JIY0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS16415
gene id: 571913:VV02_RS16415
uniprot id: A0A0K1JK37
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

571913:VV02 RS09045
gene id: 571913:VV02_RS09045
uniprot id: A0A0K1JGY1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

571913:VV02 RS20985
gene id: 571913:VV02_RS20985
uniprot id: A0A0K1JM28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

571913:VV02 RS16905
gene id: 571913:VV02_RS16905
uniprot id: A0A0K1JKA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

571913:VV02 RS19070
gene id: 571913:VV02_RS19070
uniprot id: A0A0K1JL66
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

571913:VV02 RS18515
gene id: 571913:VV02_RS18515
uniprot id: A0A0K1JQT6
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS08385
gene id: 571913:VV02_RS08385
uniprot id: A0A0K1JGP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

571913:VV02 RS13220
gene id: 571913:VV02_RS13220
uniprot id: A0A0K1JIQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

571913:VV02 RS20490
gene id: 571913:VV02_RS20490
uniprot id: A0A0K1JM65
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

571913:VV02 RS12630
gene id: 571913:VV02_RS12630
uniprot id: A0A0K1JIJ0
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

571913:VV02 RS25660
gene id: 571913:VV02_RS25660
uniprot id: A0A0K1JPF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

571913:VV02 RS06580
gene id: 571913:VV02_RS06580
uniprot id: A0A0K1JFW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

571913:VV02 RS10045
gene id: 571913:VV02_RS10045
uniprot id: A0A0K1JHR3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS02735
gene id: 571913:VV02_RS02735
uniprot id: A0A0K1JEL1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

571913:VV02 RS00200
gene id: 571913:VV02_RS00200
uniprot id: A0A0K1JD82
names: Similarity
messages: Belongs to the pirin family.

571913:VV02 RS09690
gene id: 571913:VV02_RS09690
uniprot id: A0A0K1JHK9
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

571913:VV02 RS10380
gene id: 571913:VV02_RS10380
uniprot id: A0A0K1JHW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

571913:VV02 RS17780
gene id: 571913:VV02_RS17780
uniprot id: A0A0K1JL37
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

571913:VV02 RS17775
gene id: 571913:VV02_RS17775
uniprot id: A0A0K1JKN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS11810
gene id: 571913:VV02_RS11810
uniprot id: A0A0K1JIJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

571913:VV02 RS00130
gene id: 571913:VV02_RS00130
uniprot id: A0A0K1JD66
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

571913:VV02 RS19545
gene id: 571913:VV02_RS19545
uniprot id: A0A0K1JLE6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

571913:VV02 RS11730
gene id: 571913:VV02_RS11730
uniprot id: A0A0K1JII4
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

571913:VV02 RS13815
gene id: 571913:VV02_RS13815
uniprot id: A0A0K1JJ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS09560
gene id: 571913:VV02_RS09560
uniprot id: A0A0K1JH76
names: Similarity
messages: Belongs to the Nudix hydrolase family.

571913:VV02 RS21650
gene id: 571913:VV02_RS21650
uniprot id: A0A0K1JMQ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS19175
gene id: 571913:VV02_RS19175
uniprot id: A0A0K1JQW0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

571913:VV02 RS08445
gene id: 571913:VV02_RS08445
uniprot id: A0A0K1JH20
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS06570
gene id: 571913:VV02_RS06570
uniprot id: A0A0K1JG70
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

571913:VV02 RS18115
gene id: 571913:VV02_RS18115
uniprot id: A0A0K1JL84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

571913:VV02 RS03850
gene id: 571913:VV02_RS03850
uniprot id: A0A0K1JES6
names: Similarity
messages: Belongs to the thioredoxin family.

571913:VV02 RS15160
gene id: 571913:VV02_RS15160
uniprot id: A0A0K1JJJ9
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

571913:VV02 RS02370
gene id: 571913:VV02_RS02370
uniprot id: A0A0K1JPP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

571913:VV02 RS25140
gene id: 571913:VV02_RS25140
uniprot id: A0A0K1JP66
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

571913:VV02 RS16335
gene id: 571913:VV02_RS16335
uniprot id: A0A0K1JKG5
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

571913:VV02 RS13635
gene id: 571913:VV02_RS13635
uniprot id: A0A0K1JIY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

571913:VV02 RS04260
gene id: 571913:VV02_RS04260
uniprot id: A0A0K1JFA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS18235
gene id: 571913:VV02_RS18235
uniprot id: A0A0K1JKU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS23280
gene id: 571913:VV02_RS23280
uniprot id: A0A0K1JN34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

571913:VV02 RS02200
gene id: 571913:VV02_RS02200
uniprot id: A0A0K1JE28
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS05350
gene id: 571913:VV02_RS05350
uniprot id: A0A0K1JPY5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

571913:VV02 RS14685
gene id: 571913:VV02_RS14685
uniprot id: A0A0K1JJF1
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

571913:VV02 RS21895
gene id: 571913:VV02_RS21895
uniprot id: A0A0K1JMV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm

571913:VV02 RS23015
gene id: 571913:VV02_RS23015
uniprot id: A0A0K1JMX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS06550
gene id: 571913:VV02_RS06550
uniprot id: A0A0K1JFV5
names: Similarity
messages: Belongs to the IMPACT family.

571913:VV02 RS07370
gene id: 571913:VV02_RS07370
uniprot id: A0A0K1JPU5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS18825
gene id: 571913:VV02_RS18825
uniprot id: A0A0K1JQU8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

571913:VV02 RS09390
gene id: 571913:VV02_RS09390
uniprot id: A0A0K1JH37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

571913:VV02 RS21985
gene id: 571913:VV02_RS21985
uniprot id: A0A0K1JMI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

571913:VV02 RS15080
gene id: 571913:VV02_RS15080
uniprot id: A0A0K1JJI9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

571913:VV02 RS20965
gene id: 571913:VV02_RS20965
uniprot id: A0A0K1JM20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

571913:VV02 RS21365
gene id: 571913:VV02_RS21365
uniprot id: A0A0K1JM85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

571913:VV02 RS04225
gene id: 571913:VV02_RS04225
uniprot id: A0A0K1JF97
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS21605
gene id: 571913:VV02_RS21605
uniprot id: A0A0K1JMQ4
names: Similarity
messages: Belongs to the UPF0234 family.

571913:VV02 RS08965
gene id: 571913:VV02_RS08965
uniprot id: A0A0K1JGX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

571913:VV02 RS13910
gene id: 571913:VV02_RS13910
uniprot id: A0A0K1JJ46
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

571913:VV02 RS13955
gene id: 571913:VV02_RS13955
uniprot id: A0A0K1JQU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

571913:VV02 RS18925
gene id: 571913:VV02_RS18925
uniprot id: A0A0K1JL55
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

571913:VV02 RS20230
gene id: 571913:VV02_RS20230
uniprot id: A0A0K1JM21
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS18470
gene id: 571913:VV02_RS18470
uniprot id: A0A0K1JKX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

571913:VV02 RS01760
gene id: 571913:VV02_RS01760
uniprot id: A0A0K1JE74
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

571913:VV02 RS17965
gene id: 571913:VV02_RS17965
uniprot id: A0A0K1JKR2
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS24095
gene id: 571913:VV02_RS24095
uniprot id: A0A0K1JNE2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

571913:VV02 RS14070
gene id: 571913:VV02_RS14070
uniprot id: A0A0K1JJ57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

571913:VV02 RS19035
gene id: 571913:VV02_RS19035
uniprot id: A0A0K1JL62
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

571913:VV02 RS12470
gene id: 571913:VV02_RS12470
uniprot id: A0A0K1JIU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

571913:VV02 RS13795
gene id: 571913:VV02_RS13795
uniprot id: A0A0K1JJ31
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

571913:VV02 RS24845
gene id: 571913:VV02_RS24845
uniprot id: A0A0K1JP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS05080
gene id: 571913:VV02_RS05080
uniprot id: A0A0K1JFA3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS11895
gene id: 571913:VV02_RS11895
uniprot id: A0A0K1JQ58
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS13605
gene id: 571913:VV02_RS13605
uniprot id: A0A0K1JJA0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

571913:VV02 RS03690
gene id: 571913:VV02_RS03690
uniprot id: A0A0K1JEQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

571913:VV02 RS21510
gene id: 571913:VV02_RS21510
uniprot id: A0A0K1JMN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

571913:VV02 RS07390
gene id: 571913:VV02_RS07390
uniprot id: A0A0K1JG98
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

571913:VV02 RS10415
gene id: 571913:VV02_RS10415
uniprot id: A0A0K1JHX3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS12130
gene id: 571913:VV02_RS12130
uniprot id: A0A0K1JIA3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

571913:VV02 RS18150
gene id: 571913:VV02_RS18150
uniprot id: A0A0K1JL89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

571913:VV02 RS12285
gene id: 571913:VV02_RS12285
uniprot id: A0A0K1JIE3
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

571913:VV02 RS21045
gene id: 571913:VV02_RS21045
uniprot id: A0A0K1JMG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

571913:VV02 RS09150
gene id: 571913:VV02_RS09150
uniprot id: A0A0K1JQF3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

571913:VV02 RS14010
gene id: 571913:VV02_RS14010
uniprot id: A0A0K1JJI6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

571913:VV02 RS02425
gene id: 571913:VV02_RS02425
uniprot id: A0A0K1JEH3
names: Similarity
messages: Belongs to the thioredoxin family.

571913:VV02 RS20520
gene id: 571913:VV02_RS20520
uniprot id: A0A0K1JLT6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS11190
gene id: 571913:VV02_RS11190
uniprot id: A0A0K1JIA1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS18620
gene id: 571913:VV02_RS18620
uniprot id: A0A0K1JL16
names: Similarity
messages: Belongs to the EfeM/EfeO family.

571913:VV02 RS25000
gene id: 571913:VV02_RS25000
uniprot id: A0A0K1JNQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

571913:VV02 RS02540
gene id: 571913:VV02_RS02540
uniprot id: A0A0K1JE64
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

571913:VV02 RS05370
gene id: 571913:VV02_RS05370
uniprot id: A0A0K1JFE9
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS23085
gene id: 571913:VV02_RS23085
uniprot id: A0A0K1JNB3
names: Similarity
messages: Belongs to the peptidase S13 family.

571913:VV02 RS10980
gene id: 571913:VV02_RS10980
uniprot id: A0A0K1JHV1
names: Similarity
messages: Belongs to the DapA family.

571913:VV02 RS18215
gene id: 571913:VV02_RS18215
uniprot id: A0A0K1JL98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

571913:VV02 RS02135
gene id: 571913:VV02_RS02135
uniprot id: A0A0K1JPC2
names: Similarity
messages: Belongs to the Vsr family.

571913:VV02 RS21015
gene id: 571913:VV02_RS21015
uniprot id: A0A0K1JM30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

571913:VV02 RS09270
gene id: 571913:VV02_RS09270
uniprot id: A0A0K1JH15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

571913:VV02 RS01070
gene id: 571913:VV02_RS01070
uniprot id: A0A0K1JDK9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

571913:VV02 RS22530
gene id: 571913:VV02_RS22530
uniprot id: A0A0K1JMR3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

571913:VV02 RS12495
gene id: 571913:VV02_RS12495
uniprot id: A0A0K1JIF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

571913:VV02 RS16240
gene id: 571913:VV02_RS16240
uniprot id: A0A0K1JK34
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

571913:VV02 RS19400
gene id: 571913:VV02_RS19400
uniprot id: A0A0K1JQW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

571913:VV02 RS13310
gene id: 571913:VV02_RS13310
uniprot id: A0A0K1JIS2
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS18615
gene id: 571913:VV02_RS18615
uniprot id: A0A0K1JLF4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

571913:VV02 RS17795
gene id: 571913:VV02_RS17795
uniprot id: A0A0K1JL32
names: Similarity
messages: Belongs to the CFA/CMAS family.

571913:VV02 RS24720
gene id: 571913:VV02_RS24720
uniprot id: A0A0K1JP01
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

571913:VV02 RS03635
gene id: 571913:VV02_RS03635
uniprot id: A0A0K1JEN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

571913:VV02 RS01345
gene id: 571913:VV02_RS01345
uniprot id: A0A0K1JDP4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

571913:VV02 RS21165
gene id: 571913:VV02_RS21165
uniprot id: A0A0K1JMI8
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS02660
gene id: 571913:VV02_RS02660
uniprot id: A0A0K1JE80
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS07100
gene id: 571913:VV02_RS07100
uniprot id: A0A0K1JGF1
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

571913:VV02 RS03420
gene id: 571913:VV02_RS03420
uniprot id: A0A0K1JEL5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

571913:VV02 RS13735
gene id: 571913:VV02_RS13735
uniprot id: A0A0K1JJ08
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS22755
gene id: 571913:VV02_RS22755
uniprot id: A0A0K1JMU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

571913:VV02 RS18930
gene id: 571913:VV02_RS18930
uniprot id: A0A0K1JL47
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

571913:VV02 RS13960
gene id: 571913:VV02_RS13960
uniprot id: A0A0K1JJH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

571913:VV02 RS04265
gene id: 571913:VV02_RS04265
uniprot id: A0A0K1JEZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS02895
gene id: 571913:VV02_RS02895
uniprot id: A0A0K1JEN4
names: Similarity
messages: Belongs to the AHA1 family.

571913:VV02 RS17525
gene id: 571913:VV02_RS17525
uniprot id: A0A0K1JKL5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS14440
gene id: 571913:VV02_RS14440
uniprot id: A0A0K1JJC4
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

571913:VV02 RS07365
gene id: 571913:VV02_RS07365
uniprot id: A0A0K1JQ68
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

571913:VV02 RS11630
gene id: 571913:VV02_RS11630
uniprot id: A0A0K1JIG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

571913:VV02 RS15425
gene id: 571913:VV02_RS15425
uniprot id: A0A0K1JK35
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS21345
gene id: 571913:VV02_RS21345
uniprot id: A0A0K1JM84
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS11130
gene id: 571913:VV02_RS11130
uniprot id: A0A0K1JHW0
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS12765
gene id: 571913:VV02_RS12765
uniprot id: A0A0K1JQ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

571913:VV02 RS10540
gene id: 571913:VV02_RS10540
uniprot id: A0A0K1JHM9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

571913:VV02 RS06310
gene id: 571913:VV02_RS06310
uniprot id: A0A0K1JG46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

571913:VV02 RS05765
gene id: 571913:VV02_RS05765
uniprot id: A0A0K1JQ22
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

571913:VV02 RS13430
gene id: 571913:VV02_RS13430
uniprot id: A0A0K1JIW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

571913:VV02 RS10025
gene id: 571913:VV02_RS10025
uniprot id: A0A0K1JHD6
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

571913:VV02 RS18565
gene id: 571913:VV02_RS18565
uniprot id: A0A0K1JLE5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

571913:VV02 RS14005
gene id: 571913:VV02_RS14005
uniprot id: A0A0K1JJ43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

571913:VV02 RS05975
gene id: 571913:VV02_RS05975
uniprot id: A0A0K1JFZ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

571913:VV02 RS19245
gene id: 571913:VV02_RS19245
uniprot id: A0A0K1JL86
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

571913:VV02 RS14435
gene id: 571913:VV02_RS14435
uniprot id: A0A0K1JJQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

571913:VV02 RS24875
gene id: 571913:VV02_RS24875
uniprot id: A0A0K1JNP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS03205
gene id: 571913:VV02_RS03205
uniprot id: A0A0K1JEG4
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

571913:VV02 RS24970
gene id: 571913:VV02_RS24970
uniprot id: A0A0K1JNQ3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

571913:VV02 RS21195
gene id: 571913:VV02_RS21195
uniprot id: A0A0K1JM61
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

571913:VV02 RS13855
gene id: 571913:VV02_RS13855
uniprot id: A0A0K1JQB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

571913:VV02 RS24345
gene id: 571913:VV02_RS24345
uniprot id: A0A0K1JNV3
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS20165
gene id: 571913:VV02_RS20165
uniprot id: A0A0K1JM10
names: Similarity
messages: Belongs to the peptidase M24B family.

571913:VV02 RS17440
gene id: 571913:VV02_RS17440
uniprot id: A0A0K1JKY3
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

571913:VV02 RS17890
gene id: 571913:VV02_RS17890
uniprot id: A0A0K1JKR1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS12730
gene id: 571913:VV02_RS12730
uniprot id: A0A0K1JIK4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS17845
gene id: 571913:VV02_RS17845
uniprot id: A0A0K1JL44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

571913:VV02 RS20495
gene id: 571913:VV02_RS20495
uniprot id: A0A0K1JLU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

571913:VV02 RS10170
gene id: 571913:VV02_RS10170
uniprot id: A0A0K1JHT5
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

571913:VV02 RS05255
gene id: 571913:VV02_RS05255
uniprot id: A0A0K1JFQ1
names: Similarity
messages: Belongs to the peptidase C1 family.

571913:VV02 RS17655
gene id: 571913:VV02_RS17655
uniprot id: A0A0K1JKM5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS20075
gene id: 571913:VV02_RS20075
uniprot id: A0A0K1JQZ0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

571913:VV02 RS08885
gene id: 571913:VV02_RS08885
uniprot id: A0A0K1JH89
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS08430
gene id: 571913:VV02_RS08430
uniprot id: A0A0K1JGN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS17220
gene id: 571913:VV02_RS17220
uniprot id: A0A0K1JKV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS09145
gene id: 571913:VV02_RS09145
uniprot id: A0A0K1JH04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS19550
gene id: 571913:VV02_RS19550
uniprot id: A0A0K1JQX4
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

571913:VV02 RS13630
gene id: 571913:VV02_RS13630
uniprot id: A0A0K1JJA7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS12335
gene id: 571913:VV02_RS12335
uniprot id: A0A0K1JIS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

571913:VV02 RS27195
gene id: 571913:VV02_RS27195
uniprot id: A0A0K1JKV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

571913:VV02 RS25365
gene id: 571913:VV02_RS25365
uniprot id: A0A0K1JNX4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

571913:VV02 RS16470
gene id: 571913:VV02_RS16470
uniprot id: A0A0K1JK65
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS13525
gene id: 571913:VV02_RS13525
uniprot id: A0A0K1JIX9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

571913:VV02 RS11900
gene id: 571913:VV02_RS11900
uniprot id: A0A0K1JI66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

571913:VV02 RS01090
gene id: 571913:VV02_RS01090
uniprot id: A0A0K1JP79
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

571913:VV02 RS11560
gene id: 571913:VV02_RS11560
uniprot id: A0A0K1JIF7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

571913:VV02 RS07345
gene id: 571913:VV02_RS07345
uniprot id: A0A0K1JG94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

571913:VV02 RS21095
gene id: 571913:VV02_RS21095
uniprot id: A0A0K1JR21
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

571913:VV02 RS20370
gene id: 571913:VV02_RS20370
uniprot id: A0A0K1JLS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

571913:VV02 RS18255
gene id: 571913:VV02_RS18255
uniprot id: A0A0K1JKV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

571913:VV02 RS05675
gene id: 571913:VV02_RS05675
uniprot id: A0A0K1JFK2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

571913:VV02 RS08330
gene id: 571913:VV02_RS08330
uniprot id: A0A0K1JGL8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

571913:VV02 RS10695
gene id: 571913:VV02_RS10695
uniprot id: A0A0K1JHP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

571913:VV02 RS17905
gene id: 571913:VV02_RS17905
uniprot id: A0A0K1JL48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

571913:VV02 RS21700
gene id: 571913:VV02_RS21700
uniprot id: A0A0K1JMS2
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS03060
gene id: 571913:VV02_RS03060
uniprot id: A0A0K1JEF7
names: Similarity
messages: Belongs to the peptidase S51 family.

571913:VV02 RS19800
gene id: 571913:VV02_RS19800
uniprot id: A0A0K1JLW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

571913:VV02 RS08075
gene id: 571913:VV02_RS08075
uniprot id: A0A0K1JGW7
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS09700
gene id: 571913:VV02_RS09700
uniprot id: A0A0K1JH87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

571913:VV02 RS20880
gene id: 571913:VV02_RS20880
uniprot id: A0A0K1JME0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS10150
gene id: 571913:VV02_RS10150
uniprot id: A0A0K1JHH4
names: Similarity
messages: Belongs to the TPP enzyme family.

571913:VV02 RS14350
gene id: 571913:VV02_RS14350
uniprot id: A0A0K1JJB0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

571913:VV02 RS11720
gene id: 571913:VV02_RS11720
uniprot id: A0A0K1JI39
names: Similarity
messages: Belongs to the malate synthase family.

571913:VV02 RS08480
gene id: 571913:VV02_RS08480
uniprot id: A0A0K1JGP1
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

571913:VV02 RS24120
gene id: 571913:VV02_RS24120
uniprot id: A0A0K1JNE8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

571913:VV02 RS09505
gene id: 571913:VV02_RS09505
uniprot id: A0A0K1JH60
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

571913:VV02 RS12360
gene id: 571913:VV02_RS12360
uniprot id: A0A0K1JID8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

571913:VV02 RS21405
gene id: 571913:VV02_RS21405
uniprot id: A0A0K1JM90
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS10940
gene id: 571913:VV02_RS10940
uniprot id: A0A0K1JHT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

571913:VV02 RS19490
gene id: 571913:VV02_RS19490
uniprot id: A0A0K1JLD2
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

571913:VV02 RS19410
gene id: 571913:VV02_RS19410
uniprot id: A0A0K1JLC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

571913:VV02 RS04555
gene id: 571913:VV02_RS04555
uniprot id: A0A0K1JFE2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

571913:VV02 RS23470
gene id: 571913:VV02_RS23470
uniprot id: A0A0K1JRN8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

571913:VV02 RS21470
gene id: 571913:VV02_RS21470
uniprot id: A0A0K1JM95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

571913:VV02 RS25530
gene id: 571913:VV02_RS25530
uniprot id: A0A0K1JPF3
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

571913:VV02 RS22025
gene id: 571913:VV02_RS22025
uniprot id: A0A0K1JMW8
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

571913:VV02 RS17055
gene id: 571913:VV02_RS17055
uniprot id: A0A0K1JKD5
names: Similarity
messages: Belongs to the GcvT family.

571913:VV02 RS19430
gene id: 571913:VV02_RS19430
uniprot id: A0A0K1JLB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS00030
gene id: 571913:VV02_RS00030
uniprot id: A0A0K1JD53
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS10200
gene id: 571913:VV02_RS10200
uniprot id: A0A0K1JHG1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

571913:VV02 RS04850
gene id: 571913:VV02_RS04850
uniprot id: A0A0K1JFK0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

571913:VV02 RS12860
gene id: 571913:VV02_RS12860
uniprot id: A0A0K1JIZ4
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS19810
gene id: 571913:VV02_RS19810
uniprot id: A0A0K1JLW1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS15930
gene id: 571913:VV02_RS15930
uniprot id: A0A0K1JQI8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

571913:VV02 RS09940
gene id: 571913:VV02_RS09940
uniprot id: A0A0K1JHP6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

571913:VV02 RS11195
gene id: 571913:VV02_RS11195
uniprot id: A0A0K1JHX1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

571913:VV02 RS02015
gene id: 571913:VV02_RS02015
uniprot id: A0A0K1JDY8
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS22000
gene id: 571913:VV02_RS22000
uniprot id: A0A0K1JMW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

571913:VV02 RS11780
gene id: 571913:VV02_RS11780
uniprot id: A0A0K1JI65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

571913:VV02 RS14140
gene id: 571913:VV02_RS14140
uniprot id: A0A0K1JJK7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

571913:VV02 RS22360
gene id: 571913:VV02_RS22360
uniprot id: A0A0K1JMN5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS19900
gene id: 571913:VV02_RS19900
uniprot id: A0A0K1JLX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS12925
gene id: 571913:VV02_RS12925
uniprot id: A0A0K1JJ01
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

571913:VV02 RS20645
gene id: 571913:VV02_RS20645
uniprot id: A0A0K1JLX1
names: Subcellular Location Annotation
messages: Cytoplasm

571913:VV02 RS10825
gene id: 571913:VV02_RS10825
uniprot id: A0A0K1JHR2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

571913:VV02 RS14530
gene id: 571913:VV02_RS14530
uniprot id: A0A0K1JJC0
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS20110
gene id: 571913:VV02_RS20110
uniprot id: A0A0K1JLN1
names: Similarity
messages: Belongs to the DEAD box helicase family.

571913:VV02 RS09800
gene id: 571913:VV02_RS09800
uniprot id: A0A0K1JHA1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

571913:VV02 RS19640
gene id: 571913:VV02_RS19640
uniprot id: A0A0K1JLG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

571913:VV02 RS18050
gene id: 571913:VV02_RS18050
uniprot id: A0A0K1JL74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

571913:VV02 RS22065
gene id: 571913:VV02_RS22065
uniprot id: A0A0K1JMX3
names: Similarity
messages: Belongs to the isochorismate synthase family.

571913:VV02 RS08495
gene id: 571913:VV02_RS08495
uniprot id: A0A0K1JGQ2
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS04415
gene id: 571913:VV02_RS04415
uniprot id: A0A0K1JEZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

571913:VV02 RS23480
gene id: 571913:VV02_RS23480
uniprot id: A0A0K1JN60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

571913:VV02 RS19385
gene id: 571913:VV02_RS19385
uniprot id: A0A0K1JLB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

571913:VV02 RS12175
gene id: 571913:VV02_RS12175
uniprot id: A0A0K1JIB3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

571913:VV02 RS22330
gene id: 571913:VV02_RS22330
uniprot id: A0A0K1JN10
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

571913:VV02 RS25005
gene id: 571913:VV02_RS25005
uniprot id: A0A0K1JP63
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

571913:VV02 RS19540
gene id: 571913:VV02_RS19540
uniprot id: A0A0K1JLS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

571913:VV02 RS23330
gene id: 571913:VV02_RS23330
uniprot id: A0A0K1JN32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

571913:VV02 RS00510
gene id: 571913:VV02_RS00510
uniprot id: A0A0K1JDQ1
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS04195
gene id: 571913:VV02_RS04195
uniprot id: A0A0K1JF92
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS22340
gene id: 571913:VV02_RS22340
uniprot id: A0A0K1JN19
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

571913:VV02 RS19290
gene id: 571913:VV02_RS19290
uniprot id: A0A0K1JQW4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

571913:VV02 RS22035
gene id: 571913:VV02_RS22035
uniprot id: A0A0K1JMI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

571913:VV02 RS09785
gene id: 571913:VV02_RS09785
uniprot id: A0A0K1JHL9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

571913:VV02 RS17390
gene id: 571913:VV02_RS17390
uniprot id: A0A0K1JKK0
names: Similarity
messages: Belongs to the SufE family.

571913:VV02 RS20730
gene id: 571913:VV02_RS20730
uniprot id: A0A0K1JLY3
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS03435
gene id: 571913:VV02_RS03435
uniprot id: A0A0K1JEK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

571913:VV02 RS21855
gene id: 571913:VV02_RS21855
uniprot id: A0A0K1JME8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

571913:VV02 RS02870
gene id: 571913:VV02_RS02870
uniprot id: A0A0K1JPE4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

571913:VV02 RS20915
gene id: 571913:VV02_RS20915
uniprot id: A0A0K1JM14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

571913:VV02 RS14620
gene id: 571913:VV02_RS14620
uniprot id: A0A0K1JJD7
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS21280
gene id: 571913:VV02_RS21280
uniprot id: A0A0K1JM76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

571913:VV02 RS20515
gene id: 571913:VV02_RS20515
uniprot id: A0A0K1JRG6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS21300
gene id: 571913:VV02_RS21300
uniprot id: A0A0K1JM77
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

571913:VV02 RS05615
gene id: 571913:VV02_RS05615
uniprot id: A0A0K1JFW3
names: Similarity
messages: Belongs to the universal stress protein A family.

571913:VV02 RS07230
gene id: 571913:VV02_RS07230
uniprot id: A0A0K1JGI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

571913:VV02 RS18295
gene id: 571913:VV02_RS18295
uniprot id: A0A0K1JLA8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

571913:VV02 RS16070
gene id: 571913:VV02_RS16070
uniprot id: A0A0K1JJZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

571913:VV02 RS19045
gene id: 571913:VV02_RS19045
uniprot id: A0A0K1JL61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

571913:VV02 RS20905
gene id: 571913:VV02_RS20905
uniprot id: A0A0K1JM12
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

571913:VV02 RS19870
gene id: 571913:VV02_RS19870
uniprot id: A0A0K1JRE2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS01720
gene id: 571913:VV02_RS01720
uniprot id: A0A0K1JDV1
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS14110
gene id: 571913:VV02_RS14110
uniprot id: A0A0K1JJ58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

571913:VV02 RS17610
gene id: 571913:VV02_RS17610
uniprot id: A0A0K1JL14
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS08185
gene id: 571913:VV02_RS08185
uniprot id: A0A0K1JGJ8
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS12165
gene id: 571913:VV02_RS12165
uniprot id: A0A0K1JIP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS11665
gene id: 571913:VV02_RS11665
uniprot id: A0A0K1JI34
names: Similarity
messages: Belongs to the peptidase C40 family.

571913:VV02 RS17635
gene id: 571913:VV02_RS17635
uniprot id: A0A0K1JKL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

571913:VV02 RS17075
gene id: 571913:VV02_RS17075
uniprot id: A0A0K1JKF2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

571913:VV02 RS19495
gene id: 571913:VV02_RS19495
uniprot id: A0A0K1JLS1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

571913:VV02 RS02000
gene id: 571913:VV02_RS02000
uniprot id: A0A0K1JEB5
names: Similarity
messages: Belongs to the UPF0749 family.

571913:VV02 RS03875
gene id: 571913:VV02_RS03875
uniprot id: A0A0K1JF50
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

571913:VV02 RS02595
gene id: 571913:VV02_RS02595
uniprot id: A0A0K1JE83
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

571913:VV02 RS26950
gene id: 571913:VV02_RS26950
uniprot id: A0A0K1JKI9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

571913:VV02 RS22430
gene id: 571913:VV02_RS22430
uniprot id: A0A0K1JRK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

571913:VV02 RS21695
gene id: 571913:VV02_RS21695
uniprot id: A0A0K1JMC8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

571913:VV02 RS22395
gene id: 571913:VV02_RS22395
uniprot id: A0A0K1JN20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

571913:VV02 RS05565
gene id: 571913:VV02_RS05565
uniprot id: A0A0K1JFG8
names: Similarity
messages: Belongs to the universal stress protein A family.

571913:VV02 RS17310
gene id: 571913:VV02_RS17310
uniprot id: A0A0K1JKJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

571913:VV02 RS12405
gene id: 571913:VV02_RS12405
uniprot id: A0A0K1JQ74
names: Similarity
messages: Belongs to the ABC transporter superfamily.

571913:VV02 RS07040
gene id: 571913:VV02_RS07040
uniprot id: A0A0K1JG42
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS12080
gene id: 571913:VV02_RS12080
uniprot id: A0A0K1JIN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

571913:VV02 RS09415
gene id: 571913:VV02_RS09415
uniprot id: A0A0K1JQG5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

571913:VV02 RS02865
gene id: 571913:VV02_RS02865
uniprot id: A0A0K1JEM9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS02550
gene id: 571913:VV02_RS02550
uniprot id: A0A0K1JE77
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

571913:VV02 RS02400
gene id: 571913:VV02_RS02400
uniprot id: A0A0K1JE53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

571913:VV02 RS20765
gene id: 571913:VV02_RS20765
uniprot id: A0A0K1JLY8
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS09835
gene id: 571913:VV02_RS09835
uniprot id: A0A0K1JHM6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

571913:VV02 RS23435
gene id: 571913:VV02_RS23435
uniprot id: A0A0K1JNF7
names: Similarity
messages: Belongs to the universal stress protein A family.

571913:VV02 RS20955
gene id: 571913:VV02_RS20955
uniprot id: A0A0K1JMF0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

571913:VV02 RS16515
gene id: 571913:VV02_RS16515
uniprot id: A0A0K1JKI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

571913:VV02 RS00475
gene id: 571913:VV02_RS00475
uniprot id: A0A0K1JDP6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

571913:VV02 RS01335
gene id: 571913:VV02_RS01335
uniprot id: A0A0K1JE16
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS07175
gene id: 571913:VV02_RS07175
uniprot id: A0A0K1JG56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

571913:VV02 RS00380
gene id: 571913:VV02_RS00380
uniprot id: A0A0K1JDK8
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS13580
gene id: 571913:VV02_RS13580
uniprot id: A0A0K1JIX0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

571913:VV02 RS24765
gene id: 571913:VV02_RS24765
uniprot id: A0A0K1JNM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS15075
gene id: 571913:VV02_RS15075
uniprot id: A0A0K1JJY2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

571913:VV02 RS04810
gene id: 571913:VV02_RS04810
uniprot id: A0A0K1JPK8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

571913:VV02 RS12855
gene id: 571913:VV02_RS12855
uniprot id: A0A0K1JIK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

571913:VV02 RS15510
gene id: 571913:VV02_RS15510
uniprot id: A0A0K1JK50
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS18800
gene id: 571913:VV02_RS18800
uniprot id: A0A0K1JL35
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

571913:VV02 RS05510
gene id: 571913:VV02_RS05510
uniprot id: A0A0K1JFH4
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

571913:VV02 RS05440
gene id: 571913:VV02_RS05440
uniprot id: A0A0K1JFE8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

571913:VV02 RS22630
gene id: 571913:VV02_RS22630
uniprot id: A0A0K1JN54
names: Similarity
messages: Belongs to the ABC transporter superfamily.

571913:VV02 RS13880
gene id: 571913:VV02_RS13880
uniprot id: A0A0K1JJ29
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

571913:VV02 RS07905
gene id: 571913:VV02_RS07905
uniprot id: A0A0K1JGH8
names: Similarity
messages: Belongs to the group II decarboxylase family.

571913:VV02 RS04540
gene id: 571913:VV02_RS04540
uniprot id: A0A0K1JF14
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

571913:VV02 RS02880
gene id: 571913:VV02_RS02880
uniprot id: A0A0K1JEB1
names: Similarity
messages: Belongs to the peptidase C40 family.

571913:VV02 RS19535
gene id: 571913:VV02_RS19535
uniprot id: A0A0K1JLD0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS19395
gene id: 571913:VV02_RS19395
uniprot id: A0A0K1JLB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

571913:VV02 RS21965
gene id: 571913:VV02_RS21965
uniprot id: A0A0K1JMH7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

571913:VV02 RS07945
gene id: 571913:VV02_RS07945
uniprot id: A0A0K1JGH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

571913:VV02 RS17335
gene id: 571913:VV02_RS17335
uniprot id: A0A0K1JKH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

571913:VV02 RS18760
gene id: 571913:VV02_RS18760
uniprot id: A0A0K1JL30
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

571913:VV02 RS18035
gene id: 571913:VV02_RS18035
uniprot id: A0A0K1JL73
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS14045
gene id: 571913:VV02_RS14045
uniprot id: A0A0K1JJ67
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

571913:VV02 RS12815
gene id: 571913:VV02_RS12815
uniprot id: A0A0K1JIJ8
names: Similarity
messages: Belongs to the CapA family.

571913:VV02 RS10975
gene id: 571913:VV02_RS10975
uniprot id: A0A0K1JI68
names: Similarity
messages: Belongs to the proline racemase family.

571913:VV02 RS13835
gene id: 571913:VV02_RS13835
uniprot id: A0A0K1JJ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

571913:VV02 RS24885
gene id: 571913:VV02_RS24885
uniprot id: A0A0K1JNP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

571913:VV02 RS14600
gene id: 571913:VV02_RS14600
uniprot id: A0A0K1JJC9
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS10855
gene id: 571913:VV02_RS10855
uniprot id: A0A0K1JHR7
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS09450
gene id: 571913:VV02_RS09450
uniprot id: A0A0K1JHH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

571913:VV02 RS24545
gene id: 571913:VV02_RS24545
uniprot id: A0A0K1JRD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

571913:VV02 RS14500
gene id: 571913:VV02_RS14500
uniprot id: A0A0K1JJB6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS01445
gene id: 571913:VV02_RS01445
uniprot id: A0A0K1JDQ9
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS25425
gene id: 571913:VV02_RS25425
uniprot id: A0A0K1JNY4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

571913:VV02 RS17240
gene id: 571913:VV02_RS17240
uniprot id: A0A0K1JKI2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

571913:VV02 RS13625
gene id: 571913:VV02_RS13625
uniprot id: A0A0K1JIY8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

571913:VV02 RS25335
gene id: 571913:VV02_RS25335
uniprot id: A0A0K1JNW9
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS24650
gene id: 571913:VV02_RS24650
uniprot id: A0A0K1JNL5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

571913:VV02 RS16910
gene id: 571913:VV02_RS16910
uniprot id: A0A0K1JKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

571913:VV02 RS22010
gene id: 571913:VV02_RS22010
uniprot id: A0A0K1JMX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

571913:VV02 RS18000
gene id: 571913:VV02_RS18000
uniprot id: A0A0K1JL63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

571913:VV02 RS02310
gene id: 571913:VV02_RS02310
uniprot id: A0A0K1JE42
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

571913:VV02 RS25190
gene id: 571913:VV02_RS25190
uniprot id: A0A0K1JNU1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

571913:VV02 RS22650
gene id: 571913:VV02_RS22650
uniprot id: A0A0K1JMT7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

571913:VV02 RS24415
gene id: 571913:VV02_RS24415
uniprot id: A0A0K1JNW1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

571913:VV02 RS25030
gene id: 571913:VV02_RS25030
uniprot id: A0A0K1JNR2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

571913:VV02 RS17270
gene id: 571913:VV02_RS17270
uniprot id: A0A0K1JKH0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

571913:VV02 RS18860
gene id: 571913:VV02_RS18860
uniprot id: A0A0K1JL45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS15945
gene id: 571913:VV02_RS15945
uniprot id: A0A0K1JKA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

571913:VV02 RS17060
gene id: 571913:VV02_RS17060
uniprot id: A0A0K1JKQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

571913:VV02 RS11025
gene id: 571913:VV02_RS11025
uniprot id: A0A0K1JHU2
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS08345
gene id: 571913:VV02_RS08345
uniprot id: A0A0K1JGM9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

571913:VV02 RS13285
gene id: 571913:VV02_RS13285
uniprot id: A0A0K1JQA3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

571913:VV02 RS23090
gene id: 571913:VV02_RS23090
uniprot id: A0A0K1JMZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

571913:VV02 RS20620
gene id: 571913:VV02_RS20620
uniprot id: A0A0K1JLW5
names: Similarity
messages: Belongs to the thioredoxin family.

571913:VV02 RS12945
gene id: 571913:VV02_RS12945
uniprot id: A0A0K1JIN6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

571913:VV02 RS18070
gene id: 571913:VV02_RS18070
uniprot id: A0A0K1JKU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

571913:VV02 RS04770
gene id: 571913:VV02_RS04770
uniprot id: A0A0K1JF65
names: Similarity
messages: Belongs to the Nudix hydrolase family.

571913:VV02 RS11830
gene id: 571913:VV02_RS11830
uniprot id: A0A0K1JI56
names: Similarity
messages: Belongs to the DprA/Smf family.

571913:VV02 RS05025
gene id: 571913:VV02_RS05025
uniprot id: A0A0K1JF93
names: Similarity
messages: Belongs to the glutathione peroxidase family.

571913:VV02 RS22580
gene id: 571913:VV02_RS22580
uniprot id: A0A0K1JMR5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

571913:VV02 RS20655
gene id: 571913:VV02_RS20655
uniprot id: A0A0K1JR14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

571913:VV02 RS14135
gene id: 571913:VV02_RS14135
uniprot id: A0A0K1JJ62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

571913:VV02 RS20640
gene id: 571913:VV02_RS20640
uniprot id: A0A0K1JLX0
names: Similarity
messages: Belongs to the peptidase S33 family.

571913:VV02 RS05725
gene id: 571913:VV02_RS05725
uniprot id: A0A0K1JFL1
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS04115
gene id: 571913:VV02_RS04115
uniprot id: A0A0K1JEV5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS24965
gene id: 571913:VV02_RS24965
uniprot id: A0A0K1JP40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

571913:VV02 RS12055
gene id: 571913:VV02_RS12055
uniprot id: A0A0K1JIN3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

571913:VV02 RS06270
gene id: 571913:VV02_RS06270
uniprot id: A0A0K1JFT0
names: Similarity
messages: Belongs to the GARS family.

571913:VV02 RS10480
gene id: 571913:VV02_RS10480
uniprot id: A0A0K1JHM0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

571913:VV02 RS05330
gene id: 571913:VV02_RS05330
uniprot id: A0A0K1JFE4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS02485
gene id: 571913:VV02_RS02485
uniprot id: A0A0K1JE67
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS18535
gene id: 571913:VV02_RS18535
uniprot id: A0A0K1JLE0
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

571913:VV02 RS09695
gene id: 571913:VV02_RS09695
uniprot id: A0A0K1JHA3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

571913:VV02 RS00235
gene id: 571913:VV02_RS00235
uniprot id: A0A0K1JD88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

571913:VV02 RS20935
gene id: 571913:VV02_RS20935
uniprot id: A0A0K1JR17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

571913:VV02 RS22405
gene id: 571913:VV02_RS22405
uniprot id: A0A0K1JN29
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS02915
gene id: 571913:VV02_RS02915
uniprot id: A0A0K1JEC8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

571913:VV02 RS13215
gene id: 571913:VV02_RS13215
uniprot id: A0A0K1JJ33
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

571913:VV02 RS10935
gene id: 571913:VV02_RS10935
uniprot id: A0A0K1JI62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

571913:VV02 RS24880
gene id: 571913:VV02_RS24880
uniprot id: A0A0K1JP25
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

571913:VV02 RS25450
gene id: 571913:VV02_RS25450
uniprot id: A0A0K1JNY9
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

571913:VV02 RS05365
gene id: 571913:VV02_RS05365
uniprot id: A0A0K1JFS2
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS25155
gene id: 571913:VV02_RS25155
uniprot id: A0A0K1JNU0
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

571913:VV02 RS08990
gene id: 571913:VV02_RS08990
uniprot id: A0A0K1JGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

571913:VV02 RS01575
gene id: 571913:VV02_RS01575
uniprot id: A0A0K1JDT2
names: Similarity
messages: Belongs to the AHA1 family.

571913:VV02 RS17305
gene id: 571913:VV02_RS17305
uniprot id: A0A0K1JKX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

571913:VV02 RS19285
gene id: 571913:VV02_RS19285
uniprot id: A0A0K1JL97
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

571913:VV02 RS21305
gene id: 571913:VV02_RS21305
uniprot id: A0A0K1JML3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

571913:VV02 RS19660
gene id: 571913:VV02_RS19660
uniprot id: A0A0K1JLU7
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS15210
gene id: 571913:VV02_RS15210
uniprot id: A0A0K1JJM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

571913:VV02 RS23295
gene id: 571913:VV02_RS23295
uniprot id: A0A0K1JN27
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

571913:VV02 RS25130
gene id: 571913:VV02_RS25130
uniprot id: A0A0K1JNT5
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS13600
gene id: 571913:VV02_RS13600
uniprot id: A0A0K1JIY3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

571913:VV02 RS05910
gene id: 571913:VV02_RS05910
uniprot id: A0A0K1JFN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

571913:VV02 RS03610
gene id: 571913:VV02_RS03610
uniprot id: A0A0K1JEM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS10395
gene id: 571913:VV02_RS10395
uniprot id: A0A0K1JHK7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS15335
gene id: 571913:VV02_RS15335
uniprot id: A0A0K1JK14
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

571913:VV02 RS22465
gene id: 571913:VV02_RS22465
uniprot id: A0A0K1JMQ3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

571913:VV02 RS14080
gene id: 571913:VV02_RS14080
uniprot id: A0A0K1JJ53
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS14460
gene id: 571913:VV02_RS14460
uniprot id: A0A0K1JJP5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

571913:VV02 RS24910
gene id: 571913:VV02_RS24910
uniprot id: A0A0K1JP30
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS04420
gene id: 571913:VV02_RS04420
uniprot id: A0A0K1JFD1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

571913:VV02 RS04425
gene id: 571913:VV02_RS04425
uniprot id: A0A0K1JF10
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

571913:VV02 RS11795
gene id: 571913:VV02_RS11795
uniprot id: A0A0K1JI51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

571913:VV02 RS15795
gene id: 571913:VV02_RS15795
uniprot id: A0A0K1JJV7
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

571913:VV02 RS14910
gene id: 571913:VV02_RS14910
uniprot id: A0A0K1JJG3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS17300
gene id: 571913:VV02_RS17300
uniprot id: A0A0K1JKH1
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS15455
gene id: 571913:VV02_RS15455
uniprot id: A0A0K1JK40
names: Similarity
messages: Belongs to the AHA1 family.

571913:VV02 RS24155
gene id: 571913:VV02_RS24155
uniprot id: A0A0K1JNF1
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS24560
gene id: 571913:VV02_RS24560
uniprot id: A0A0K1JNJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS11070
gene id: 571913:VV02_RS11070
uniprot id: A0A0K1JHV2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

571913:VV02 RS20265
gene id: 571913:VV02_RS20265
uniprot id: A0A0K1JLP5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

571913:VV02 RS24610
gene id: 571913:VV02_RS24610
uniprot id: A0A0K1JP00
names: Subcellular Location Annotation
messages: Cytoplasm

571913:VV02 RS00690
gene id: 571913:VV02_RS00690
uniprot id: A0A0K1JDG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

571913:VV02 RS16860
gene id: 571913:VV02_RS16860
uniprot id: A0A0K1JKM7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS11450
gene id: 571913:VV02_RS11450
uniprot id: A0A0K1JHZ8
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

571913:VV02 RS13615
gene id: 571913:VV02_RS13615
uniprot id: A0A0K1JJA9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

571913:VV02 RS03130
gene id: 571913:VV02_RS03130
uniprot id: A0A0K1JEF3
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

571913:VV02 RS09495
gene id: 571913:VV02_RS09495
uniprot id: A0A0K1JH53
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

571913:VV02 RS18385
gene id: 571913:VV02_RS18385
uniprot id: A0A0K1JLC3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS07900
gene id: 571913:VV02_RS07900
uniprot id: A0A0K1JPU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

571913:VV02 RS06480
gene id: 571913:VV02_RS06480
uniprot id: A0A0K1JG69
names: Similarity
messages: Belongs to the SAICAR synthetase family.

571913:VV02 RS11265
gene id: 571913:VV02_RS11265
uniprot id: A0A0K1JHX6
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS19280
gene id: 571913:VV02_RS19280
uniprot id: A0A0K1JLA5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

571913:VV02 RS04100
gene id: 571913:VV02_RS04100
uniprot id: A0A0K1JEW4
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS11655
gene id: 571913:VV02_RS11655
uniprot id: A0A0K1JIH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

571913:VV02 RS21050
gene id: 571913:VV02_RS21050
uniprot id: A0A0K1JM39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

571913:VV02 RS16275
gene id: 571913:VV02_RS16275
uniprot id: A0A0K1JK39
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS26905
gene id: 571913:VV02_RS26905
uniprot id: A0A0K1JHY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

571913:VV02 RS13915
gene id: 571913:VV02_RS13915
uniprot id: A0A0K1JJ34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

571913:VV02 RS17815
gene id: 571913:VV02_RS17815
uniprot id: A0A0K1JKQ1
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS06160
gene id: 571913:VV02_RS06160
uniprot id: A0A0K1JQ08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

571913:VV02 RS02440
gene id: 571913:VV02_RS02440
uniprot id: A0A0K1JEH1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

571913:VV02 RS07280
gene id: 571913:VV02_RS07280
uniprot id: A0A0K1JG73
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

571913:VV02 RS20995
gene id: 571913:VV02_RS20995
uniprot id: A0A0K1JMF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

571913:VV02 RS23450
gene id: 571913:VV02_RS23450
uniprot id: A0A0K1JN55
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

571913:VV02 RS25300
gene id: 571913:VV02_RS25300
uniprot id: A0A0K1JNV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

571913:VV02 RS13965
gene id: 571913:VV02_RS13965
uniprot id: A0A0K1JJ54
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS12715
gene id: 571913:VV02_RS12715
uniprot id: A0A0K1JII8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

571913:VV02 RS09715
gene id: 571913:VV02_RS09715
uniprot id: A0A0K1JH97
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS09245
gene id: 571913:VV02_RS09245
uniprot id: A0A0K1JQF8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

571913:VV02 RS21235
gene id: 571913:VV02_RS21235
uniprot id: A0A0K1JMJ7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

571913:VV02 RS19455
gene id: 571913:VV02_RS19455
uniprot id: A0A0K1JLC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

571913:VV02 RS00275
gene id: 571913:VV02_RS00275
uniprot id: A0A0K1JDJ0
names: Similarity
messages: Belongs to the CsoR family.

571913:VV02 RS06870
gene id: 571913:VV02_RS06870
uniprot id: A0A0K1JG16
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS06060
gene id: 571913:VV02_RS06060
uniprot id: A0A0K1JPN9
names: Similarity
messages: Belongs to the UPF0098 family.

571913:VV02 RS06930
gene id: 571913:VV02_RS06930
uniprot id: A0A0K1JG12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS04405
gene id: 571913:VV02_RS04405
uniprot id: A0A0K1JF12
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

571913:VV02 RS19315
gene id: 571913:VV02_RS19315
uniprot id: A0A0K1JLB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

571913:VV02 RS13850
gene id: 571913:VV02_RS13850
uniprot id: A0A0K1JJF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

571913:VV02 RS04150
gene id: 571913:VV02_RS04150
uniprot id: A0A0K1JF96
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

571913:VV02 RS20975
gene id: 571913:VV02_RS20975
uniprot id: A0A0K1JM24
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

571913:VV02 RS16580
gene id: 571913:VV02_RS16580
uniprot id: A0A0K1JK66
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

571913:VV02 RS15915
gene id: 571913:VV02_RS15915
uniprot id: A0A0K1JK99
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

571913:VV02 RS09515
gene id: 571913:VV02_RS09515
uniprot id: A0A0K1JH72
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS21255
gene id: 571913:VV02_RS21255
uniprot id: A0A0K1JM68
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

571913:VV02 RS20485
gene id: 571913:VV02_RS20485
uniprot id: A0A0K1JLT0
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

571913:VV02 RS25415
gene id: 571913:VV02_RS25415
uniprot id: A0A0K1JNX6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

571913:VV02 RS10195
gene id: 571913:VV02_RS10195
uniprot id: A0A0K1JQI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

571913:VV02 RS23540
gene id: 571913:VV02_RS23540
uniprot id: A0A0K1JN58
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

571913:VV02 RS09530
gene id: 571913:VV02_RS09530
uniprot id: A0A0K1JHJ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

571913:VV02 RS10455
gene id: 571913:VV02_RS10455
uniprot id: A0A0K1JHX8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

571913:VV02 RS17115
gene id: 571913:VV02_RS17115
uniprot id: A0A0K1JKS0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

571913:VV02 RS24135
gene id: 571913:VV02_RS24135
uniprot id: A0A0K1JNU2
names: Similarity
messages: Belongs to the IucA/IucC family.

571913:VV02 RS06020
gene id: 571913:VV02_RS06020
uniprot id: A0A0K1JG02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

571913:VV02 RS03660
gene id: 571913:VV02_RS03660
uniprot id: A0A0K1JEP5
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS06150
gene id: 571913:VV02_RS06150
uniprot id: A0A0K1JFR8
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS20990
gene id: 571913:VV02_RS20990
uniprot id: A0A0K1JM25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

571913:VV02 RS21565
gene id: 571913:VV02_RS21565
uniprot id: A0A0K1JMB3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

571913:VV02 RS13930
gene id: 571913:VV02_RS13930
uniprot id: A0A0K1JJH4
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

571913:VV02 RS08000
gene id: 571913:VV02_RS08000
uniprot id: A0A0K1JGI3
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

571913:VV02 RS11170
gene id: 571913:VV02_RS11170
uniprot id: A0A0K1JHW5
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

571913:VV02 RS15105
gene id: 571913:VV02_RS15105
uniprot id: A0A0K1JJJ4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

571913:VV02 RS13065
gene id: 571913:VV02_RS13065
uniprot id: A0A0K1JIN2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

571913:VV02 RS05430
gene id: 571913:VV02_RS05430
uniprot id: A0A0K1JFS4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

571913:VV02 RS21905
gene id: 571913:VV02_RS21905
uniprot id: A0A0K1JMF7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

571913:VV02 RS12005
gene id: 571913:VV02_RS12005
uniprot id: A0A0K1JIM4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS21270
gene id: 571913:VV02_RS21270
uniprot id: A0A0K1JM72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

571913:VV02 RS11310
gene id: 571913:VV02_RS11310
uniprot id: A0A0K1JQM2
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

571913:VV02 RS18580
gene id: 571913:VV02_RS18580
uniprot id: A0A0K1JL11
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS19165
gene id: 571913:VV02_RS19165
uniprot id: A0A0K1JLM5
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

571913:VV02 RS02580
gene id: 571913:VV02_RS02580
uniprot id: A0A0K1JEJ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

571913:VV02 RS17150
gene id: 571913:VV02_RS17150
uniprot id: A0A0K1JKE4
names: Similarity
messages: Belongs to the glutamine synthetase family.

571913:VV02 RS20615
gene id: 571913:VV02_RS20615
uniprot id: A0A0K1JM98
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

571913:VV02 RS12830
gene id: 571913:VV02_RS12830
uniprot id: A0A0K1JIY9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

571913:VV02 RS20325
gene id: 571913:VV02_RS20325
uniprot id: A0A0K1JM36
names: Similarity
messages: Belongs to the citrate synthase family.

571913:VV02 RS12300
gene id: 571913:VV02_RS12300
uniprot id: A0A0K1JIR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

571913:VV02 RS06575
gene id: 571913:VV02_RS06575
uniprot id: A0A0K1JFX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

571913:VV02 RS06125
gene id: 571913:VV02_RS06125
uniprot id: A0A0K1JFP5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

571913:VV02 RS09010
gene id: 571913:VV02_RS09010
uniprot id: A0A0K1JHA5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

571913:VV02 RS16540
gene id: 571913:VV02_RS16540
uniprot id: A0A0K1JK77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS00465
gene id: 571913:VV02_RS00465
uniprot id: A0A0K1JDD3
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS13875
gene id: 571913:VV02_RS13875
uniprot id: A0A0K1JJ41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

571913:VV02 RS11150
gene id: 571913:VV02_RS11150
uniprot id: A0A0K1JHW1
names: Similarity
messages: Belongs to the peptidase S58 family.

571913:VV02 RS21040
gene id: 571913:VV02_RS21040
uniprot id: A0A0K1JM35
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

571913:VV02 RS13935
gene id: 571913:VV02_RS13935
uniprot id: A0A0K1JJ51
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

571913:VV02 RS17295
gene id: 571913:VV02_RS17295
uniprot id: A0A0K1JKW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS13975
gene id: 571913:VV02_RS13975
uniprot id: A0A0K1JJH3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS10365
gene id: 571913:VV02_RS10365
uniprot id: A0A0K1JHW4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

571913:VV02 RS24255
gene id: 571913:VV02_RS24255
uniprot id: A0A0K1JNH6
names: Similarity
messages: Belongs to the AHA1 family.

571913:VV02 RS11740
gene id: 571913:VV02_RS11740
uniprot id: A0A0K1JII1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

571913:VV02 RS23025
gene id: 571913:VV02_RS23025
uniprot id: A0A0K1JMY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

571913:VV02 RS12670
gene id: 571913:VV02_RS12670
uniprot id: A0A0K1JIW6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS07085
gene id: 571913:VV02_RS07085
uniprot id: A0A0K1JG34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

571913:VV02 RS05490
gene id: 571913:VV02_RS05490
uniprot id: A0A0K1JFT4
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS17090
gene id: 571913:VV02_RS17090
uniprot id: A0A0K1JKR3
names: Similarity
messages: Belongs to the citrate synthase family.

571913:VV02 RS15830
gene id: 571913:VV02_RS15830
uniprot id: A0A0K1JJV2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

571913:VV02 RS01975
gene id: 571913:VV02_RS01975
uniprot id: A0A0K1JDZ2
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS22495
gene id: 571913:VV02_RS22495
uniprot id: A0A0K1JMR0
names: Similarity
messages: Belongs to the histone deacetylase family.

571913:VV02 RS20930
gene id: 571913:VV02_RS20930
uniprot id: A0A0K1JM16
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

571913:VV02 RS21945
gene id: 571913:VV02_RS21945
uniprot id: A0A0K1JMW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

571913:VV02 RS16730
gene id: 571913:VV02_RS16730
uniprot id: A0A0K1JKL9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

571913:VV02 RS25295
gene id: 571913:VV02_RS25295
uniprot id: A0A0K1JP90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

571913:VV02 RS21940
gene id: 571913:VV02_RS21940
uniprot id: A0A0K1JMH4
names: Similarity
messages: Belongs to the peptidase M1 family.

571913:VV02 RS20290
gene id: 571913:VV02_RS20290
uniprot id: A0A0K1JLQ0
names: Similarity
messages: Belongs to the LOG family.

571913:VV02 RS05960
gene id: 571913:VV02_RS05960
uniprot id: A0A0K1JFL8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

571913:VV02 RS11015
gene id: 571913:VV02_RS11015
uniprot id: A0A0K1JHV7
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

571913:VV02 RS21025
gene id: 571913:VV02_RS21025
uniprot id: A0A0K1JM34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

571913:VV02 RS19335
gene id: 571913:VV02_RS19335
uniprot id: A0A0K1JLP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

571913:VV02 RS09955
gene id: 571913:VV02_RS09955
uniprot id: A0A0K1JHE4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

571913:VV02 RS10680
gene id: 571913:VV02_RS10680
uniprot id: A0A0K1JHP5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

571913:VV02 RS14030
gene id: 571913:VV02_RS14030
uniprot id: A0A0K1JJ48
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

571913:VV02 RS18880
gene id: 571913:VV02_RS18880
uniprot id: A0A0K1JLI8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

571913:VV02 RS23790
gene id: 571913:VV02_RS23790
uniprot id: A0A0K1JNL7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

571913:VV02 RS20380
gene id: 571913:VV02_RS20380
uniprot id: A0A0K1JM46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

571913:VV02 RS16935
gene id: 571913:VV02_RS16935
uniprot id: A0A0K1JKQ4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

571913:VV02 RS09625
gene id: 571913:VV02_RS09625
uniprot id: A0A0K1JH70
names: Similarity
messages: Belongs to the creatininase superfamily.

571913:VV02 RS18015
gene id: 571913:VV02_RS18015
uniprot id: A0A0K1JL68
names: Similarity
messages: Belongs to the FPG family.

571913:VV02 RS12145
gene id: 571913:VV02_RS12145
uniprot id: A0A0K1JIA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

571913:VV02 RS24990
gene id: 571913:VV02_RS24990
uniprot id: A0A0K1JP46
names: Similarity
messages: Belongs to the XFP family.

571913:VV02 RS18545
gene id: 571913:VV02_RS18545
uniprot id: A0A0K1JKY5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

571913:VV02 RS07990
gene id: 571913:VV02_RS07990
uniprot id: A0A0K1JGH6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

571913:VV02 RS20920
gene id: 571913:VV02_RS20920
uniprot id: A0A0K1JME5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

571913:VV02 RS14740
gene id: 571913:VV02_RS14740
uniprot id: A0A0K1JJU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS11060
gene id: 571913:VV02_RS11060
uniprot id: A0A0K1JHU8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

571913:VV02 RS22715
gene id: 571913:VV02_RS22715
uniprot id: A0A0K1JN73
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

571913:VV02 RS23410
gene id: 571913:VV02_RS23410
uniprot id: A0A0K1JN36
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS14150
gene id: 571913:VV02_RS14150
uniprot id: A0A0K1JJ72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

571913:VV02 RS19465
gene id: 571913:VV02_RS19465
uniprot id: A0A0K1JLC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS12980
gene id: 571913:VV02_RS12980
uniprot id: A0A0K1JIM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS12225
gene id: 571913:VV02_RS12225
uniprot id: A0A0K1JIB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS12365
gene id: 571913:VV02_RS12365
uniprot id: A0A0K1JIS9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

571913:VV02 RS18590
gene id: 571913:VV02_RS18590
uniprot id: A0A0K1JL00
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

571913:VV02 RS08650
gene id: 571913:VV02_RS08650
uniprot id: A0A0K1JGR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

571913:VV02 RS17015
gene id: 571913:VV02_RS17015
uniprot id: A0A0K1JKE3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

571913:VV02 RS09920
gene id: 571913:VV02_RS09920
uniprot id: A0A0K1JHN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS10850
gene id: 571913:VV02_RS10850
uniprot id: A0A0K1JHT2
names: Similarity
messages: Belongs to the GSP E family.

571913:VV02 RS18450
gene id: 571913:VV02_RS18450
uniprot id: A0A0K1JKY1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

571913:VV02 RS19675
gene id: 571913:VV02_RS19675
uniprot id: A0A0K1JLV0
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS21275
gene id: 571913:VV02_RS21275
uniprot id: A0A0K1JMK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

571913:VV02 RS19390
gene id: 571913:VV02_RS19390
uniprot id: A0A0K1JLQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

571913:VV02 RS20585
gene id: 571913:VV02_RS20585
uniprot id: A0A0K1JLV3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

571913:VV02 RS11270
gene id: 571913:VV02_RS11270
uniprot id: A0A0K1JIB1
names: Similarity
messages: Belongs to the LOG family.

571913:VV02 RS17805
gene id: 571913:VV02_RS17805
uniprot id: A0A0K1JL39
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS19620
gene id: 571913:VV02_RS19620
uniprot id: A0A0K1JLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS05900
gene id: 571913:VV02_RS05900
uniprot id: A0A0K1JFM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS16880
gene id: 571913:VV02_RS16880
uniprot id: A0A0K1JKP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

571913:VV02 RS16310
gene id: 571913:VV02_RS16310
uniprot id: A0A0K1JKG1
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS14490
gene id: 571913:VV02_RS14490
uniprot id: A0A0K1JJC1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

571913:VV02 RS10000
gene id: 571913:VV02_RS10000
uniprot id: A0A0K1JHQ6
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS19500
gene id: 571913:VV02_RS19500
uniprot id: A0A0K1JLC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

571913:VV02 RS14025
gene id: 571913:VV02_RS14025
uniprot id: A0A0K1JJI4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

571913:VV02 RS17660
gene id: 571913:VV02_RS17660
uniprot id: A0A0K1JL12
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS00420
gene id: 571913:VV02_RS00420
uniprot id: A0A0K1JDL7
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS11490
gene id: 571913:VV02_RS11490
uniprot id: A0A0K1JIE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

571913:VV02 RS14575
gene id: 571913:VV02_RS14575
uniprot id: A0A0K1JJC5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

571913:VV02 RS21030
gene id: 571913:VV02_RS21030
uniprot id: A0A0K1JMG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

571913:VV02 RS16895
gene id: 571913:VV02_RS16895
uniprot id: A0A0K1JKB0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS14405
gene id: 571913:VV02_RS14405
uniprot id: A0A0K1JJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

571913:VV02 RS18840
gene id: 571913:VV02_RS18840
uniprot id: A0A0K1JL33
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS14535
gene id: 571913:VV02_RS14535
uniprot id: A0A0K1JQD7
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS22015
gene id: 571913:VV02_RS22015
uniprot id: A0A0K1JMI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

571913:VV02 RS22605
gene id: 571913:VV02_RS22605
uniprot id: A0A0K1JMR8
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

571913:VV02 RS13495
gene id: 571913:VV02_RS13495
uniprot id: A0A0K1JIX4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

571913:VV02 RS20130
gene id: 571913:VV02_RS20130
uniprot id: A0A0K1JLM4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

571913:VV02 RS18155
gene id: 571913:VV02_RS18155
uniprot id: A0A0K1JKT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

571913:VV02 RS15705
gene id: 571913:VV02_RS15705
uniprot id: A0A0K1JQI5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

571913:VV02 RS17950
gene id: 571913:VV02_RS17950
uniprot id: A0A0K1JKS3
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

571913:VV02 RS09720
gene id: 571913:VV02_RS09720
uniprot id: A0A0K1JHL2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

571913:VV02 RS01785
gene id: 571913:VV02_RS01785
uniprot id: A0A0K1JDV3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

571913:VV02 RS15300
gene id: 571913:VV02_RS15300
uniprot id: A0A0K1JK21
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

571913:VV02 RS25675
gene id: 571913:VV02_RS25675
uniprot id: A0A0K1JP33
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

571913:VV02 RS07800
gene id: 571913:VV02_RS07800
uniprot id: A0A0K1JGG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Vgb family.
messages: Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.
messages: Monomer.

571913:VV02 RS07090
gene id: 571913:VV02_RS07090
uniprot id: A0A0K1JGG0
names: Similarity
messages: Belongs to the PstS family.

571913:VV02 RS10340
gene id: 571913:VV02_RS10340
uniprot id: A0A0K1JHJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

571913:VV02 RS20630
gene id: 571913:VV02_RS20630
uniprot id: A0A0K1JR12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

571913:VV02 RS24130
gene id: 571913:VV02_RS24130
uniprot id: A0A0K1JNE7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

571913:VV02 RS12230
gene id: 571913:VV02_RS12230
uniprot id: A0A0K1JIQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS04630
gene id: 571913:VV02_RS04630
uniprot id: A0A0K1JPK2
names: Similarity
messages: Belongs to the fructosamine kinase family.

571913:VV02 RS16460
gene id: 571913:VV02_RS16460
uniprot id: A0A0K1JKI1
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

571913:VV02 RS08265
gene id: 571913:VV02_RS08265
uniprot id: A0A0K1JGK8
names: Similarity
messages: Belongs to the sulfatase family.

571913:VV02 RS14085
gene id: 571913:VV02_RS14085
uniprot id: A0A0K1JJJ8
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS21430
gene id: 571913:VV02_RS21430
uniprot id: A0A0K1JM93
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

571913:VV02 RS17630
gene id: 571913:VV02_RS17630
uniprot id: A0A0K1JL06
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

571913:VV02 RS03530
gene id: 571913:VV02_RS03530
uniprot id: A0A0K1JEM8
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS08920
gene id: 571913:VV02_RS08920
uniprot id: A0A0K1JH94
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

571913:VV02 RS11835
gene id: 571913:VV02_RS11835
uniprot id: A0A0K1JIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

571913:VV02 RS12455
gene id: 571913:VV02_RS12455
uniprot id: A0A0K1JIT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

571913:VV02 RS17030
gene id: 571913:VV02_RS17030
uniprot id: A0A0K1JKQ3
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS18730
gene id: 571913:VV02_RS18730
uniprot id: A0A0K1JL25
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS08230
gene id: 571913:VV02_RS08230
uniprot id: A0A0K1JGK3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

571913:VV02 RS13830
gene id: 571913:VV02_RS13830
uniprot id: A0A0K1JQU4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

571913:VV02 RS24745
gene id: 571913:VV02_RS24745
uniprot id: A0A0K1JNM9
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS15180
gene id: 571913:VV02_RS15180
uniprot id: A0A0K1JJL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

571913:VV02 RS15355
gene id: 571913:VV02_RS15355
uniprot id: A0A0K1JJN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

571913:VV02 RS13925
gene id: 571913:VV02_RS13925
uniprot id: A0A0K1JJ30
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS12750
gene id: 571913:VV02_RS12750
uniprot id: A0A0K1JIJ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

571913:VV02 RS15970
gene id: 571913:VV02_RS15970
uniprot id: A0A0K1JJY0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

571913:VV02 RS25305
gene id: 571913:VV02_RS25305
uniprot id: A0A0K1JPA4
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS14775
gene id: 571913:VV02_RS14775
uniprot id: A0A0K1JJG6
names: Similarity
messages: Belongs to the UPF0098 family.

571913:VV02 RS00590
gene id: 571913:VV02_RS00590
uniprot id: A0A0K1JDE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS15340
gene id: 571913:VV02_RS15340
uniprot id: A0A0K1JJL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

571913:VV02 RS11785
gene id: 571913:VV02_RS11785
uniprot id: A0A0K1JI49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

571913:VV02 RS09265
gene id: 571913:VV02_RS09265
uniprot id: A0A0K1JH33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

571913:VV02 RS09190
gene id: 571913:VV02_RS09190
uniprot id: A0A0K1JH09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS15845
gene id: 571913:VV02_RS15845
uniprot id: A0A0K1JK96
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

571913:VV02 RS14040
gene id: 571913:VV02_RS14040
uniprot id: A0A0K1JQC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

571913:VV02 RS02590
gene id: 571913:VV02_RS02590
uniprot id: A0A0K1JEJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

571913:VV02 RS20780
gene id: 571913:VV02_RS20780
uniprot id: A0A0K1JMC3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

571913:VV02 RS12975
gene id: 571913:VV02_RS12975
uniprot id: A0A0K1JIP1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

571913:VV02 RS11315
gene id: 571913:VV02_RS11315
uniprot id: A0A0K1JHZ1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

571913:VV02 RS22060
gene id: 571913:VV02_RS22060
uniprot id: A0A0K1JR61
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

571913:VV02 RS19100
gene id: 571913:VV02_RS19100
uniprot id: A0A0K1JLL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS03195
gene id: 571913:VV02_RS03195
uniprot id: A0A0K1JEH4
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

571913:VV02 RS02030
gene id: 571913:VV02_RS02030
uniprot id: A0A0K1JEB9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS16810
gene id: 571913:VV02_RS16810
uniprot id: A0A0K1JK89
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

571913:VV02 RS05635
gene id: 571913:VV02_RS05635
uniprot id: A0A0K1JFJ5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

571913:VV02 RS03975
gene id: 571913:VV02_RS03975
uniprot id: A0A0K1JEV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

571913:VV02 RS18495
gene id: 571913:VV02_RS18495
uniprot id: A0A0K1JR94
names: Similarity
messages: Belongs to the LacAB/RpiB family.

571913:VV02 RS15910
gene id: 571913:VV02_RS15910
uniprot id: A0A0K1JJW9
names: Function
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

571913:VV02 RS12295
gene id: 571913:VV02_RS12295
uniprot id: A0A0K1JIC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

571913:VV02 RS15825
gene id: 571913:VV02_RS15825
uniprot id: A0A0K1JJW2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

571913:VV02 RS14415
gene id: 571913:VV02_RS14415
uniprot id: A0A0K1JJB9
names: Similarity
messages: Belongs to the peptidase C40 family.

571913:VV02 RS23710
gene id: 571913:VV02_RS23710
uniprot id: A0A0K1JNJ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS04040
gene id: 571913:VV02_RS04040
uniprot id: A0A0K1JEV7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

571913:VV02 RS09195
gene id: 571913:VV02_RS09195
uniprot id: A0A0K1JHD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS25685
gene id: 571913:VV02_RS25685
uniprot id: A0A0K1JPF6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

571913:VV02 RS23285
gene id: 571913:VV02_RS23285
uniprot id: A0A0K1JN21
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

571913:VV02 RS16650
gene id: 571913:VV02_RS16650
uniprot id: A0A0K1JQL4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

571913:VV02 RS04700
gene id: 571913:VV02_RS04700
uniprot id: A0A0K1JF34
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

571913:VV02 RS23100
gene id: 571913:VV02_RS23100
uniprot id: A0A0K1JN08
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS07405
gene id: 571913:VV02_RS07405
uniprot id: A0A0K1JGA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

571913:VV02 RS17530
gene id: 571913:VV02_RS17530
uniprot id: A0A0K1JKK6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

571913:VV02 RS13410
gene id: 571913:VV02_RS13410
uniprot id: A0A0K1JIV4
names: Similarity
messages: Belongs to the glutamine synthetase family.

571913:VV02 RS08130
gene id: 571913:VV02_RS08130
uniprot id: A0A0K1JGI9
names: Similarity
messages: Belongs to the peptidase C40 family.

571913:VV02 RS23745
gene id: 571913:VV02_RS23745
uniprot id: A0A0K1JNK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

571913:VV02 RS18250
gene id: 571913:VV02_RS18250
uniprot id: A0A0K1JKV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

571913:VV02 RS21005
gene id: 571913:VV02_RS21005
uniprot id: A0A0K1JMG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

571913:VV02 RS10900
gene id: 571913:VV02_RS10900
uniprot id: A0A0K1JQ35
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

571913:VV02 RS13640
gene id: 571913:VV02_RS13640
uniprot id: A0A0K1JJB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

571913:VV02 RS24780
gene id: 571913:VV02_RS24780
uniprot id: A0A0K1JNN3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS06215
gene id: 571913:VV02_RS06215
uniprot id: A0A0K1JG33
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

571913:VV02 RS11210
gene id: 571913:VV02_RS11210
uniprot id: A0A0K1JHY2
names: Similarity
messages: Belongs to the peptidase M20A family.

571913:VV02 RS25265
gene id: 571913:VV02_RS25265
uniprot id: A0A0K1JNV1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

571913:VV02 RS25200
gene id: 571913:VV02_RS25200
uniprot id: A0A0K1JNT9
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

571913:VV02 RS06280
gene id: 571913:VV02_RS06280
uniprot id: A0A0K1JPP0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

571913:VV02 RS14780
gene id: 571913:VV02_RS14780
uniprot id: A0A0K1JJF5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

571913:VV02 RS17100
gene id: 571913:VV02_RS17100
uniprot id: A0A0K1JKT1
names: Similarity
messages: Belongs to the citrate synthase family.

571913:VV02 RS23715
gene id: 571913:VV02_RS23715
uniprot id: A0A0K1JN77
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

571913:VV02 RS20475
gene id: 571913:VV02_RS20475
uniprot id: A0A0K1JLT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

571913:VV02 RS13510
gene id: 571913:VV02_RS13510
uniprot id: A0A0K1JIW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS25505
gene id: 571913:VV02_RS25505
uniprot id: A0A0K1JPE9
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS10920
gene id: 571913:VV02_RS10920
uniprot id: A0A0K1JHU1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

571913:VV02 RS07815
gene id: 571913:VV02_RS07815
uniprot id: A0A0K1JGG4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

571913:VV02 RS17515
gene id: 571913:VV02_RS17515
uniprot id: A0A0K1JQP9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

571913:VV02 RS21715
gene id: 571913:VV02_RS21715
uniprot id: A0A0K1JMS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

571913:VV02 RS02420
gene id: 571913:VV02_RS02420
uniprot id: A0A0K1JE57
names: Similarity
messages: Belongs to the ParB family.

571913:VV02 RS14690
gene id: 571913:VV02_RS14690
uniprot id: A0A0K1JJE2
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

571913:VV02 RS06425
gene id: 571913:VV02_RS06425
uniprot id: A0A0K1JFV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

571913:VV02 RS04140
gene id: 571913:VV02_RS04140
uniprot id: A0A0K1JEV9
names: Similarity
messages: Belongs to the AHA1 family.

571913:VV02 RS20970
gene id: 571913:VV02_RS20970
uniprot id: A0A0K1JMF1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

571913:VV02 RS03055
gene id: 571913:VV02_RS03055
uniprot id: A0A0K1JER1
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS02410
gene id: 571913:VV02_RS02410
uniprot id: A0A0K1JEG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

571913:VV02 RS00425
gene id: 571913:VV02_RS00425
uniprot id: A0A0K1JDC6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

571913:VV02 RS22985
gene id: 571913:VV02_RS22985
uniprot id: A0A0K1JNA6
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS02080
gene id: 571913:VV02_RS02080
uniprot id: A0A0K1JDZ9
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

571913:VV02 RS12780
gene id: 571913:VV02_RS12780
uniprot id: A0A0K1JIY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

571913:VV02 RS23055
gene id: 571913:VV02_RS23055
uniprot id: A0A0K1JMZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

571913:VV02 RS11465
gene id: 571913:VV02_RS11465
uniprot id: A0A0K1JIE1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

571913:VV02 RS00405
gene id: 571913:VV02_RS00405
uniprot id: A0A0K1JDA2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

571913:VV02 RS08830
gene id: 571913:VV02_RS08830
uniprot id: A0A0K1JH83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS04780
gene id: 571913:VV02_RS04780
uniprot id: A0A0K1JFJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

571913:VV02 RS10190
gene id: 571913:VV02_RS10190
uniprot id: A0A0K1JHH9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

571913:VV02 RS19470
gene id: 571913:VV02_RS19470
uniprot id: A0A0K1JLR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS01430
gene id: 571913:VV02_RS01430
uniprot id: A0A0K1JDR1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

571913:VV02 RS14165
gene id: 571913:VV02_RS14165
uniprot id: A0A0K1JJL2
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

571913:VV02 RS13425
gene id: 571913:VV02_RS13425
uniprot id: A0A0K1JJ79
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

571913:VV02 RS04605
gene id: 571913:VV02_RS04605
uniprot id: A0A0K1JF23
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS01780
gene id: 571913:VV02_RS01780
uniprot id: A0A0K1JDW1
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS01280
gene id: 571913:VV02_RS01280
uniprot id: A0A0K1JPP1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

571913:VV02 RS19015
gene id: 571913:VV02_RS19015
uniprot id: A0A0K1JL56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS11880
gene id: 571913:VV02_RS11880
uniprot id: A0A0K1JI79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

571913:VV02 RS13000
gene id: 571913:VV02_RS13000
uniprot id: A0A0K1JIP6
names: Similarity
messages: Belongs to the peptidase S1 family.

571913:VV02 RS02380
gene id: 571913:VV02_RS02380
uniprot id: A0A0K1JEG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

571913:VV02 RS08440
gene id: 571913:VV02_RS08440
uniprot id: A0A0K1JGP2
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS02130
gene id: 571913:VV02_RS02130
uniprot id: A0A0K1JED4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

571913:VV02 RS07225
gene id: 571913:VV02_RS07225
uniprot id: A0A0K1JG74
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

571913:VV02 RS19815
gene id: 571913:VV02_RS19815
uniprot id: A0A0K1JLJ1
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS11470
gene id: 571913:VV02_RS11470
uniprot id: A0A0K1JI15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

571913:VV02 RS17145
gene id: 571913:VV02_RS17145
uniprot id: A0A0K1JKS7
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS23050
gene id: 571913:VV02_RS23050
uniprot id: A0A0K1JNB1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

571913:VV02 RS25385
gene id: 571913:VV02_RS25385
uniprot id: A0A0K1JRF6
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

571913:VV02 RS20785
gene id: 571913:VV02_RS20785
uniprot id: A0A0K1JLZ4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

571913:VV02 RS08140
gene id: 571913:VV02_RS08140
uniprot id: A0A0K1JGJ9
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS03105
gene id: 571913:VV02_RS03105
uniprot id: A0A0K1JER7
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

571913:VV02 RS25590
gene id: 571913:VV02_RS25590
uniprot id: A0A0K1JP13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

571913:VV02 RS21690
gene id: 571913:VV02_RS21690
uniprot id: A0A0K1JMR4
names: Similarity
messages: Belongs to the peptidase M1 family.

571913:VV02 RS18765
gene id: 571913:VV02_RS18765
uniprot id: A0A0K1JL20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

571913:VV02 RS13415
gene id: 571913:VV02_RS13415
uniprot id: A0A0K1JJ70
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

571913:VV02 RS16300
gene id: 571913:VV02_RS16300
uniprot id: A0A0K1JK19
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

571913:VV02 RS12790
gene id: 571913:VV02_RS12790
uniprot id: A0A0K1JIJ9
names: Similarity
messages: Belongs to the peptidase C40 family.

571913:VV02 RS19580
gene id: 571913:VV02_RS19580
uniprot id: A0A0K1JLT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS21395
gene id: 571913:VV02_RS21395
uniprot id: A0A0K1JM88
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

571913:VV02 RS20500
gene id: 571913:VV02_RS20500
uniprot id: A0A0K1JR05
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

571913:VV02 RS03115
gene id: 571913:VV02_RS03115
uniprot id: A0A0K1JEG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

571913:VV02 RS08195
gene id: 571913:VV02_RS08195
uniprot id: A0A0K1JGK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

571913:VV02 RS24395
gene id: 571913:VV02_RS24395
uniprot id: A0A0K1JNX5
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS22505
gene id: 571913:VV02_RS22505
uniprot id: A0A0K1JN35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

571913:VV02 RS15695
gene id: 571913:VV02_RS15695
uniprot id: A0A0K1JK68
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

571913:VV02 RS23315
gene id: 571913:VV02_RS23315
uniprot id: A0A0K1JN26
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

571913:VV02 RS21210
gene id: 571913:VV02_RS21210
uniprot id: A0A0K1JMJ2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

571913:VV02 RS23460
gene id: 571913:VV02_RS23460
uniprot id: A0A0K1JNG0
names: Subcellular Location Annotation
messages: Cytoplasm

571913:VV02 RS20540
gene id: 571913:VV02_RS20540
uniprot id: A0A0K1JLU9
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS24655
gene id: 571913:VV02_RS24655
uniprot id: A0A0K1JNZ2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

571913:VV02 RS13700
gene id: 571913:VV02_RS13700
uniprot id: A0A0K1JJ05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS14000
gene id: 571913:VV02_RS14000
uniprot id: A0A0K1JJH9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

571913:VV02 RS17160
gene id: 571913:VV02_RS17160
uniprot id: A0A0K1JKH2
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS13970
gene id: 571913:VV02_RS13970
uniprot id: A0A0K1JJ42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

571913:VV02 RS00175
gene id: 571913:VV02_RS00175
uniprot id: A0A0K1JD78
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS22470
gene id: 571913:VV02_RS22470
uniprot id: A0A0K1JMP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

571913:VV02 RS19785
gene id: 571913:VV02_RS19785
uniprot id: A0A0K1JQX9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

571913:VV02 RS05865
gene id: 571913:VV02_RS05865
uniprot id: A0A0K1JFY3
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

571913:VV02 RS02085
gene id: 571913:VV02_RS02085
uniprot id: A0A0K1JEC4
names: Similarity
messages: Belongs to the YciI family.

571913:VV02 RS12935
gene id: 571913:VV02_RS12935
uniprot id: A0A0K1JJ02
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

571913:VV02 RS19645
gene id: 571913:VV02_RS19645
uniprot id: A0A0K1JLF7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

571913:VV02 RS13610
gene id: 571913:VV02_RS13610
uniprot id: A0A0K1JIX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

571913:VV02 RS11440
gene id: 571913:VV02_RS11440
uniprot id: A0A0K1JID6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

571913:VV02 RS17375
gene id: 571913:VV02_RS17375
uniprot id: A0A0K1JKH9
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS25535
gene id: 571913:VV02_RS25535
uniprot id: A0A0K1JP04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

571913:VV02 RS17290
gene id: 571913:VV02_RS17290
uniprot id: A0A0K1JKH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

571913:VV02 RS20310
gene id: 571913:VV02_RS20310
uniprot id: A0A0K1JLR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS17330
gene id: 571913:VV02_RS17330
uniprot id: A0A0K1JKW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

571913:VV02 RS11320
gene id: 571913:VV02_RS11320
uniprot id: A0A0K1JHY4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

571913:VV02 RS05035
gene id: 571913:VV02_RS05035
uniprot id: A0A0K1JFA7
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS13400
gene id: 571913:VV02_RS13400
uniprot id: A0A0K1JJ71
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS24900
gene id: 571913:VV02_RS24900
uniprot id: A0A0K1JNQ1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

571913:VV02 RS07410
gene id: 571913:VV02_RS07410
uniprot id: A0A0K1JG93
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

571913:VV02 RS09825
gene id: 571913:VV02_RS09825
uniprot id: A0A0K1JHC3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

571913:VV02 RS02585
gene id: 571913:VV02_RS02585
uniprot id: A0A0K1JE82
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS09675
gene id: 571913:VV02_RS09675
uniprot id: A0A0K1JH82
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

571913:VV02 RS01855
gene id: 571913:VV02_RS01855
uniprot id: A0A0K1JDW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

571913:VV02 RS06510
gene id: 571913:VV02_RS06510
uniprot id: A0A0K1JFW6
names: Subcellular Location Annotation
messages: Membrane

571913:VV02 RS12235
gene id: 571913:VV02_RS12235
uniprot id: A0A0K1JIC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

571913:VV02 RS03305
gene id: 571913:VV02_RS03305
uniprot id: A0A0K1JEJ5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

571913:VV02 RS05985
gene id: 571913:VV02_RS05985
uniprot id: A0A0K1JFP2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

571913:VV02 RS16375
gene id: 571913:VV02_RS16375
uniprot id: A0A0K1JK31
names: Similarity
messages: Belongs to the thymidine kinase family.

571913:VV02 RS06830
gene id: 571913:VV02_RS06830
uniprot id: A0A0K1JG08
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.