568768:Dpoa569 RS18535
gene id: 568768:Dpoa569_RS18535
uniprot id: A0A5B8HSY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

568768:Dpoa569 RS10920
gene id: 568768:Dpoa569_RS10920
uniprot id: A0A5B8HLF6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

568768:Dpoa569 RS00515
gene id: 568768:Dpoa569_RS00515
uniprot id: A0A5B8HDQ3
names: Subcellular Location Annotation
messages: Cytoplasm

568768:Dpoa569 RS18145
gene id: 568768:Dpoa569_RS18145
uniprot id: A0A5B8IAM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

568768:Dpoa569 RS18510
gene id: 568768:Dpoa569_RS18510
uniprot id: A0A5B8IBS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

568768:Dpoa569 RS01200
gene id: 568768:Dpoa569_RS01200
uniprot id: A0A5B8HE59
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

568768:Dpoa569 RS13455
gene id: 568768:Dpoa569_RS13455
uniprot id: A0A5B8IE08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

568768:Dpoa569 RS03985
gene id: 568768:Dpoa569_RS03985
uniprot id: A0A5B8I2X5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

568768:Dpoa569 RS00425
gene id: 568768:Dpoa569_RS00425
uniprot id: A0A5B8I0G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

568768:Dpoa569 RS13330
gene id: 568768:Dpoa569_RS13330
uniprot id: A0A5B8I9B5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

568768:Dpoa569 RS06465
gene id: 568768:Dpoa569_RS06465
uniprot id: A0A5B8I4H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the rusA family.
messages: Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC.
messages: Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC.
messages: Homodimer.

568768:Dpoa569 RS03770
gene id: 568768:Dpoa569_RS03770
uniprot id: A0A5B8I2S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

568768:Dpoa569 RS05725
gene id: 568768:Dpoa569_RS05725
uniprot id: A0A5B8I8S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS07530
gene id: 568768:Dpoa569_RS07530
uniprot id: A0A5B8I3P5
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

568768:Dpoa569 RS02215
gene id: 568768:Dpoa569_RS02215
uniprot id: A0A5B8HZX6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

568768:Dpoa569 RS10160
gene id: 568768:Dpoa569_RS10160
uniprot id: A0A5B8HKR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

568768:Dpoa569 RS11315
gene id: 568768:Dpoa569_RS11315
uniprot id: A0A5B8ICJ0
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS13235
gene id: 568768:Dpoa569_RS13235
uniprot id: A0A5B8I8N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

568768:Dpoa569 RS10525
gene id: 568768:Dpoa569_RS10525
uniprot id: A0A5B8I744
names: Similarity
messages: Belongs to the GST superfamily.

568768:Dpoa569 RS15200
gene id: 568768:Dpoa569_RS15200
uniprot id: A0A5B8IAD6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

568768:Dpoa569 RS02560
gene id: 568768:Dpoa569_RS02560
uniprot id: A0A5B8I6W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

568768:Dpoa569 RS04560
gene id: 568768:Dpoa569_RS04560
uniprot id: A0A5B8ICP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

568768:Dpoa569 RS13045
gene id: 568768:Dpoa569_RS13045
uniprot id: A0A5B8IDQ0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

568768:Dpoa569 RS05675
gene id: 568768:Dpoa569_RS05675
uniprot id: A0A5B8I8Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

568768:Dpoa569 RS12305
gene id: 568768:Dpoa569_RS12305
uniprot id: A0A5B8HMJ7
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.

568768:Dpoa569 RS13565
gene id: 568768:Dpoa569_RS13565
uniprot id: A0A5B8IAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS05780
gene id: 568768:Dpoa569_RS05780
uniprot id: A0A5B8I8T7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

568768:Dpoa569 RS14520
gene id: 568768:Dpoa569_RS14520
uniprot id: A0A5B8IEP5
names: Similarity
messages: Belongs to the type IA topoisomerase family.

568768:Dpoa569 RS14685
gene id: 568768:Dpoa569_RS14685
uniprot id: A0A5B8HRH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

568768:Dpoa569 RS01525
gene id: 568768:Dpoa569_RS01525
uniprot id: A0A5B8I126
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

568768:Dpoa569 RS08940
gene id: 568768:Dpoa569_RS08940
uniprot id: A0A5B8I7V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

568768:Dpoa569 RS11870
gene id: 568768:Dpoa569_RS11870
uniprot id: A0A5B8HP93
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS11480
gene id: 568768:Dpoa569_RS11480
uniprot id: A0A5B8I9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS10695
gene id: 568768:Dpoa569_RS10695
uniprot id: A0A5B8HL85
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

568768:Dpoa569 RS02175
gene id: 568768:Dpoa569_RS02175
uniprot id: A0A5B8I1P5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

568768:Dpoa569 RS07225
gene id: 568768:Dpoa569_RS07225
uniprot id: A0A5B8I9P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

568768:Dpoa569 RS01355
gene id: 568768:Dpoa569_RS01355
uniprot id: A0A5B8I0X7
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

568768:Dpoa569 RS00575
gene id: 568768:Dpoa569_RS00575
uniprot id: A0A5B8I5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane

568768:Dpoa569 RS13650
gene id: 568768:Dpoa569_RS13650
uniprot id: A0A5B8I9I0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family. AroL subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The LID domain closes over the active site upon ATP binding.

568768:Dpoa569 RS12695
gene id: 568768:Dpoa569_RS12695
uniprot id: A0A5B8HPX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

568768:Dpoa569 RS11375
gene id: 568768:Dpoa569_RS11375
uniprot id: A0A5B8I9K1
names: Similarity
messages: Belongs to the flavodoxin family.

568768:Dpoa569 RS18210
gene id: 568768:Dpoa569_RS18210
uniprot id: A0A5B8HRJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

568768:Dpoa569 RS07635
gene id: 568768:Dpoa569_RS07635
uniprot id: A0A5B8I3R7
names: Similarity
messages: Belongs to the peptidase C40 family.

568768:Dpoa569 RS07915
gene id: 568768:Dpoa569_RS07915
uniprot id: A0A5B8I5H9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

568768:Dpoa569 RS10940
gene id: 568768:Dpoa569_RS10940
uniprot id: A0A5B8HNI7
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS03555
gene id: 568768:Dpoa569_RS03555
uniprot id: A0A5B8HFX2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

568768:Dpoa569 RS00280
gene id: 568768:Dpoa569_RS00280
uniprot id: A0A5B8HDP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS02230
gene id: 568768:Dpoa569_RS02230
uniprot id: A0A5B8HEY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

568768:Dpoa569 RS07295
gene id: 568768:Dpoa569_RS07295
uniprot id: A0A5B8HKJ8
names: Similarity
messages: Belongs to the PhoH family.

568768:Dpoa569 RS03540
gene id: 568768:Dpoa569_RS03540
uniprot id: A0A5B8I0W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

568768:Dpoa569 RS01380
gene id: 568768:Dpoa569_RS01380
uniprot id: A0A5B8HE91
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS07265
gene id: 568768:Dpoa569_RS07265
uniprot id: A0A5B8HSK3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

568768:Dpoa569 RS12850
gene id: 568768:Dpoa569_RS12850
uniprot id: A0A5B8HPS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS17905
gene id: 568768:Dpoa569_RS17905
uniprot id: A0A5B8IJD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

568768:Dpoa569 RS13280
gene id: 568768:Dpoa569_RS13280
uniprot id: A0A5B8I9A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS12390
gene id: 568768:Dpoa569_RS12390
uniprot id: A0A5B8I6Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

568768:Dpoa569 RS12470
gene id: 568768:Dpoa569_RS12470
uniprot id: A0A5B8IA81
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

568768:Dpoa569 RS16415
gene id: 568768:Dpoa569_RS16415
uniprot id: A0A5B8HSJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

568768:Dpoa569 RS08935
gene id: 568768:Dpoa569_RS08935
uniprot id: A0A5B8IAW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

568768:Dpoa569 RS03325
gene id: 568768:Dpoa569_RS03325
uniprot id: A0A5B8I2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS17390
gene id: 568768:Dpoa569_RS17390
uniprot id: A0A5B8HR27
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS13465
gene id: 568768:Dpoa569_RS13465
uniprot id: A0A5B8HQ62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

568768:Dpoa569 RS01610
gene id: 568768:Dpoa569_RS01610
uniprot id: A0A5B8I681
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

568768:Dpoa569 RS10585
gene id: 568768:Dpoa569_RS10585
uniprot id: A0A5B8HNC7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

568768:Dpoa569 RS02645
gene id: 568768:Dpoa569_RS02645
uniprot id: A0A5B8HGK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

568768:Dpoa569 RS03400
gene id: 568768:Dpoa569_RS03400
uniprot id: A0A5B8I6Y6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS02405
gene id: 568768:Dpoa569_RS02405
uniprot id: A0A5B8I1R6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

568768:Dpoa569 RS13065
gene id: 568768:Dpoa569_RS13065
uniprot id: A0A5B8I8V2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS15175
gene id: 568768:Dpoa569_RS15175
uniprot id: A0A5B8HR62
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

568768:Dpoa569 RS13270
gene id: 568768:Dpoa569_RS13270
uniprot id: A0A5B8I904
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

568768:Dpoa569 RS14925
gene id: 568768:Dpoa569_RS14925
uniprot id: A0A5B8IEX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

568768:Dpoa569 RS05770
gene id: 568768:Dpoa569_RS05770
uniprot id: A0A5B8I610
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

568768:Dpoa569 RS15710
gene id: 568768:Dpoa569_RS15710
uniprot id: A0A5B8IA29
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

568768:Dpoa569 RS12115
gene id: 568768:Dpoa569_RS12115
uniprot id: A0A5B8IER0
names: Similarity
messages: Belongs to the CFA/CMAS family.

568768:Dpoa569 RS02590
gene id: 568768:Dpoa569_RS02590
uniprot id: A0A5B8HGJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

568768:Dpoa569 RS16435
gene id: 568768:Dpoa569_RS16435
uniprot id: A0A5B8II63
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

568768:Dpoa569 RS13830
gene id: 568768:Dpoa569_RS13830
uniprot id: A0A5B8I7P7
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

568768:Dpoa569 RS15230
gene id: 568768:Dpoa569_RS15230
uniprot id: A0A5B8HR74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

568768:Dpoa569 RS01625
gene id: 568768:Dpoa569_RS01625
uniprot id: A0A5B8I155
names: Similarity
messages: Belongs to the pirin family.

568768:Dpoa569 RS19260
gene id: 568768:Dpoa569_RS19260
uniprot id: A0A5B8ID22
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

568768:Dpoa569 RS12950
gene id: 568768:Dpoa569_RS12950
uniprot id: A0A5B8IAH0
names: Subcellular Location Annotation
messages: Cytoplasm

568768:Dpoa569 RS14060
gene id: 568768:Dpoa569_RS14060
uniprot id: A0A5B8I955
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS05970
gene id: 568768:Dpoa569_RS05970
uniprot id: A0A5B8I483
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS16920
gene id: 568768:Dpoa569_RS16920
uniprot id: A0A5B8IAT4
names: Similarity
messages: Belongs to the CcdB toxin family.

568768:Dpoa569 RS04745
gene id: 568768:Dpoa569_RS04745
uniprot id: A0A5B8HGL9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

568768:Dpoa569 RS02550
gene id: 568768:Dpoa569_RS02550
uniprot id: A0A5B8I224
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

568768:Dpoa569 RS12515
gene id: 568768:Dpoa569_RS12515
uniprot id: A0A5B8HPU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

568768:Dpoa569 RS02580
gene id: 568768:Dpoa569_RS02580
uniprot id: A0A5B8I1Z1
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

568768:Dpoa569 RS12990
gene id: 568768:Dpoa569_RS12990
uniprot id: A0A5B8HQ32
names: Similarity
messages: Belongs to the SAICAR synthetase family.

568768:Dpoa569 RS11235
gene id: 568768:Dpoa569_RS11235
uniprot id: A0A5B8I7I1
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

568768:Dpoa569 RS18600
gene id: 568768:Dpoa569_RS18600
uniprot id: A0A5B8IAU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

568768:Dpoa569 RS07755
gene id: 568768:Dpoa569_RS07755
uniprot id: A0A5B8I586
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

568768:Dpoa569 RS05915
gene id: 568768:Dpoa569_RS05915
uniprot id: A0A5B8IEZ5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

568768:Dpoa569 RS18610
gene id: 568768:Dpoa569_RS18610
uniprot id: A0A5B8IBV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

568768:Dpoa569 RS02655
gene id: 568768:Dpoa569_RS02655
uniprot id: A0A5B8I2A0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

568768:Dpoa569 RS05530
gene id: 568768:Dpoa569_RS05530
uniprot id: A0A5B8I3X8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

568768:Dpoa569 RS11230
gene id: 568768:Dpoa569_RS11230
uniprot id: A0A5B8I7T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

568768:Dpoa569 RS12455
gene id: 568768:Dpoa569_RS12455
uniprot id: A0A5B8HMP4
names: Similarity
messages: Belongs to the ModE family.

568768:Dpoa569 RS02545
gene id: 568768:Dpoa569_RS02545
uniprot id: A0A5B8I6D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

568768:Dpoa569 RS02640
gene id: 568768:Dpoa569_RS02640
uniprot id: A0A5B8HF84
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS02690
gene id: 568768:Dpoa569_RS02690
uniprot id: A0A5B8HF90
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

568768:Dpoa569 RS13595
gene id: 568768:Dpoa569_RS13595
uniprot id: A0A5B8ILN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

568768:Dpoa569 RS12815
gene id: 568768:Dpoa569_RS12815
uniprot id: A0A5B8IF69
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

568768:Dpoa569 RS01120
gene id: 568768:Dpoa569_RS01120
uniprot id: A0A5B8I0R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

568768:Dpoa569 RS11215
gene id: 568768:Dpoa569_RS11215
uniprot id: A0A5B8IE57
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

568768:Dpoa569 RS11710
gene id: 568768:Dpoa569_RS11710
uniprot id: A0A5B8I7U1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

568768:Dpoa569 RS03895
gene id: 568768:Dpoa569_RS03895
uniprot id: A0A5B8IL23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

568768:Dpoa569 RS13815
gene id: 568768:Dpoa569_RS13815
uniprot id: A0A5B8HQE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

568768:Dpoa569 RS01400
gene id: 568768:Dpoa569_RS01400
uniprot id: A0A5B8I0Z5
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

568768:Dpoa569 RS03620
gene id: 568768:Dpoa569_RS03620
uniprot id: A0A5B8I2Z1
names: Similarity
messages: Belongs to the UPF0235 family.

568768:Dpoa569 RS11740
gene id: 568768:Dpoa569_RS11740
uniprot id: A0A5B8HM60
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

568768:Dpoa569 RS08695
gene id: 568768:Dpoa569_RS08695
uniprot id: A0A5B8HJL8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS05660
gene id: 568768:Dpoa569_RS05660
uniprot id: A0A5B8I8M5
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS13165
gene id: 568768:Dpoa569_RS13165
uniprot id: A0A5B8IFQ1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RcsD family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
messages: Interacts with RcsC and RcsB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated by RcsC.

568768:Dpoa569 RS17415
gene id: 568768:Dpoa569_RS17415
uniprot id: A0A5B8IJ31
names: Similarity
messages: Belongs to the pirin family.

568768:Dpoa569 RS13610
gene id: 568768:Dpoa569_RS13610
uniprot id: A0A5B8HNN3
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

568768:Dpoa569 RS07775
gene id: 568768:Dpoa569_RS07775
uniprot id: A0A5B8IA54
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

568768:Dpoa569 RS00640
gene id: 568768:Dpoa569_RS00640
uniprot id: A0A5B8I0G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

568768:Dpoa569 RS02970
gene id: 568768:Dpoa569_RS02970
uniprot id: A0A5B8HHG7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

568768:Dpoa569 RS17290
gene id: 568768:Dpoa569_RS17290
uniprot id: A0A5B8IJ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS12750
gene id: 568768:Dpoa569_RS12750
uniprot id: A0A5B8IDH1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

568768:Dpoa569 RS14005
gene id: 568768:Dpoa569_RS14005
uniprot id: A0A5B8HQY1
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

568768:Dpoa569 RS11355
gene id: 568768:Dpoa569_RS11355
uniprot id: A0A5B8I7J7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

568768:Dpoa569 RS08080
gene id: 568768:Dpoa569_RS08080
uniprot id: A0A5B8I422
names: Similarity
messages: Belongs to the PspA/IM30 family.

568768:Dpoa569 RS11805
gene id: 568768:Dpoa569_RS11805
uniprot id: A0A5B8ICW2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS15415
gene id: 568768:Dpoa569_RS15415
uniprot id: A0A5B8IFK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

568768:Dpoa569 RS15895
gene id: 568768:Dpoa569_RS15895
uniprot id: A0A5B8IHN5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

568768:Dpoa569 RS12600
gene id: 568768:Dpoa569_RS12600
uniprot id: A0A5B8IDD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS13390
gene id: 568768:Dpoa569_RS13390
uniprot id: A0A5B8I8S2
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

568768:Dpoa569 RS12630
gene id: 568768:Dpoa569_RS12630
uniprot id: A0A5B8I8U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

568768:Dpoa569 RS01510
gene id: 568768:Dpoa569_RS01510
uniprot id: A0A5B8I656
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

568768:Dpoa569 RS00500
gene id: 568768:Dpoa569_RS00500
uniprot id: A0A5B8HF13
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

568768:Dpoa569 RS16810
gene id: 568768:Dpoa569_RS16810
uniprot id: A0A5B8IAR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS05865
gene id: 568768:Dpoa569_RS05865
uniprot id: A0A5B8I8R2
names: Similarity
messages: Belongs to the peptidase A31 family.

568768:Dpoa569 RS19200
gene id: 568768:Dpoa569_RS19200
uniprot id: A0A5B8ICM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS12145
gene id: 568768:Dpoa569_RS12145
uniprot id: A0A5B8HPF9
names: Subcellular Location Annotation
messages: Cell inner membrane

568768:Dpoa569 RS01810
gene id: 568768:Dpoa569_RS01810
uniprot id: A0A5B8I5Y4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

568768:Dpoa569 RS00805
gene id: 568768:Dpoa569_RS00805
uniprot id: A0A5B8I0J8
names: Subcellular Location Annotation
messages: Cell inner membrane

568768:Dpoa569 RS01985
gene id: 568768:Dpoa569_RS01985
uniprot id: A0A5B8I611
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

568768:Dpoa569 RS04605
gene id: 568768:Dpoa569_RS04605
uniprot id: A0A5B8I571
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS08380
gene id: 568768:Dpoa569_RS08380
uniprot id: A0A5B8HJC8
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

568768:Dpoa569 RS05775
gene id: 568768:Dpoa569_RS05775
uniprot id: A0A5B8HJN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

568768:Dpoa569 RS00020
gene id: 568768:Dpoa569_RS00020
uniprot id: A0A5B8ID62
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

568768:Dpoa569 RS15735
gene id: 568768:Dpoa569_RS15735
uniprot id: A0A5B8HRH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

568768:Dpoa569 RS09650
gene id: 568768:Dpoa569_RS09650
uniprot id: A0A5B8HK59
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS02130
gene id: 568768:Dpoa569_RS02130
uniprot id: A0A5B8HEW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

568768:Dpoa569 RS05515
gene id: 568768:Dpoa569_RS05515
uniprot id: A0A5B8I2D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

568768:Dpoa569 RS02650
gene id: 568768:Dpoa569_RS02650
uniprot id: A0A5B8I6G1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS10195
gene id: 568768:Dpoa569_RS10195
uniprot id: A0A5B8I5B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

568768:Dpoa569 RS07560
gene id: 568768:Dpoa569_RS07560
uniprot id: A0A5B8I701
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS03140
gene id: 568768:Dpoa569_RS03140
uniprot id: A0A5B8I2G3
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

568768:Dpoa569 RS09100
gene id: 568768:Dpoa569_RS09100
uniprot id: A0A5B8I7Z5
names: Similarity
messages: Belongs to the fructosamine kinase family.

568768:Dpoa569 RS04910
gene id: 568768:Dpoa569_RS04910
uniprot id: A0A5B8HGP9
names: Similarity
messages: Belongs to the UPF0319 family.

568768:Dpoa569 RS09160
gene id: 568768:Dpoa569_RS09160
uniprot id: A0A5B8ICR0
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

568768:Dpoa569 RS04930
gene id: 568768:Dpoa569_RS04930
uniprot id: A0A5B8HJ29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

568768:Dpoa569 RS02960
gene id: 568768:Dpoa569_RS02960
uniprot id: A0A5B8I6P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS10215
gene id: 568768:Dpoa569_RS10215
uniprot id: A0A5B8HN08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS19050
gene id: 568768:Dpoa569_RS19050
uniprot id: A0A5B8HUC2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

568768:Dpoa569 RS11700
gene id: 568768:Dpoa569_RS11700
uniprot id: A0A5B8HP37
names: Similarity
messages: Belongs to the IucA/IucC family.

568768:Dpoa569 RS10480
gene id: 568768:Dpoa569_RS10480
uniprot id: A0A5B8HN90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

568768:Dpoa569 RS11145
gene id: 568768:Dpoa569_RS11145
uniprot id: A0A5B8ICE0
names: Similarity
messages: Belongs to the peptidase S11 family.

568768:Dpoa569 RS17385
gene id: 568768:Dpoa569_RS17385
uniprot id: A0A5B8IFE3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS15495
gene id: 568768:Dpoa569_RS15495
uniprot id: A0A5B8IAJ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS12900
gene id: 568768:Dpoa569_RS12900
uniprot id: A0A5B8HPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

568768:Dpoa569 RS10710
gene id: 568768:Dpoa569_RS10710
uniprot id: A0A5B8I971
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane

568768:Dpoa569 RS18835
gene id: 568768:Dpoa569_RS18835
uniprot id: A0A5B8IDD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

568768:Dpoa569 RS04995
gene id: 568768:Dpoa569_RS04995
uniprot id: A0A5B8I5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

568768:Dpoa569 RS07195
gene id: 568768:Dpoa569_RS07195
uniprot id: A0A5B8I3H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

568768:Dpoa569 RS00885
gene id: 568768:Dpoa569_RS00885
uniprot id: A0A5B8I5F9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

568768:Dpoa569 RS00880
gene id: 568768:Dpoa569_RS00880
uniprot id: A0A5B8HF76
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

568768:Dpoa569 RS10125
gene id: 568768:Dpoa569_RS10125
uniprot id: A0A5B8I8Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

568768:Dpoa569 RS03630
gene id: 568768:Dpoa569_RS03630
uniprot id: A0A5B8I7J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

568768:Dpoa569 RS12445
gene id: 568768:Dpoa569_RS12445
uniprot id: A0A5B8I8M6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

568768:Dpoa569 RS13255
gene id: 568768:Dpoa569_RS13255
uniprot id: A0A5B8IAP7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

568768:Dpoa569 RS17655
gene id: 568768:Dpoa569_RS17655
uniprot id: A0A5B8IJA4
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

568768:Dpoa569 RS13380
gene id: 568768:Dpoa569_RS13380
uniprot id: A0A5B8I7C3
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS10830
gene id: 568768:Dpoa569_RS10830
uniprot id: A0A5B8I994
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS05670
gene id: 568768:Dpoa569_RS05670
uniprot id: A0A5B8HJK5
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS01130
gene id: 568768:Dpoa569_RS01130
uniprot id: A0A5B8HFF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

568768:Dpoa569 RS03720
gene id: 568768:Dpoa569_RS03720
uniprot id: A0A5B8I2R0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

568768:Dpoa569 RS10960
gene id: 568768:Dpoa569_RS10960
uniprot id: A0A5B8I7M4
names: Similarity
messages: Belongs to the UPF0352 family.

568768:Dpoa569 RS15600
gene id: 568768:Dpoa569_RS15600
uniprot id: A0A5B8IA05
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS16785
gene id: 568768:Dpoa569_RS16785
uniprot id: A0A5B8IIE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS16745
gene id: 568768:Dpoa569_RS16745
uniprot id: A0A5B8IBC5
names: Similarity
messages: Belongs to the UxaA family.

568768:Dpoa569 RS16875
gene id: 568768:Dpoa569_RS16875
uniprot id: A0A5B8III3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CutA family.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in resistance toward heavy metals.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS08990
gene id: 568768:Dpoa569_RS08990
uniprot id: A0A5B8I7X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

568768:Dpoa569 RS00875
gene id: 568768:Dpoa569_RS00875
uniprot id: A0A5B8HE33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
messages: Cell inner membrane
messages: Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.
messages: Homodimer.
messages: Membrane

568768:Dpoa569 RS04245
gene id: 568768:Dpoa569_RS04245
uniprot id: A0A5B8HHZ4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

568768:Dpoa569 RS02135
gene id: 568768:Dpoa569_RS02135
uniprot id: A0A5B8HG93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

568768:Dpoa569 RS02820
gene id: 568768:Dpoa569_RS02820
uniprot id: A0A5B8HHC2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS07310
gene id: 568768:Dpoa569_RS07310
uniprot id: A0A5B8I543
names: Similarity
messages: Belongs to the LacAB/RpiB family.

568768:Dpoa569 RS15105
gene id: 568768:Dpoa569_RS15105
uniprot id: A0A5B8IAC2
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS13895
gene id: 568768:Dpoa569_RS13895
uniprot id: A0A5B8I929
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

568768:Dpoa569 RS07690
gene id: 568768:Dpoa569_RS07690
uniprot id: A0A5B8I5B6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS02105
gene id: 568768:Dpoa569_RS02105
uniprot id: A0A5B8I6L0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

568768:Dpoa569 RS03175
gene id: 568768:Dpoa569_RS03175
uniprot id: A0A5B8I6T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

568768:Dpoa569 RS10755
gene id: 568768:Dpoa569_RS10755
uniprot id: A0A5B8HL99
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

568768:Dpoa569 RS03050
gene id: 568768:Dpoa569_RS03050
uniprot id: A0A5B8I2B5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

568768:Dpoa569 RS09135
gene id: 568768:Dpoa569_RS09135
uniprot id: A0A5B8HJV9
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS07625
gene id: 568768:Dpoa569_RS07625
uniprot id: A0A5B8IBJ8
names: Function
names: Similarity
messages: Belongs to the glutathione peroxidase family. BtuE subfamily.
messages: Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.

568768:Dpoa569 RS03120
gene id: 568768:Dpoa569_RS03120
uniprot id: A0A5B8I6S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

568768:Dpoa569 RS05420
gene id: 568768:Dpoa569_RS05420
uniprot id: A0A5B8I8H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

568768:Dpoa569 RS12760
gene id: 568768:Dpoa569_RS12760
uniprot id: A0A5B8HPS4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS10355
gene id: 568768:Dpoa569_RS10355
uniprot id: A0A5B8I5G2
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

568768:Dpoa569 RS13395
gene id: 568768:Dpoa569_RS13395
uniprot id: A0A5B8HNG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

568768:Dpoa569 RS01285
gene id: 568768:Dpoa569_RS01285
uniprot id: A0A5B8I604
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

568768:Dpoa569 RS04265
gene id: 568768:Dpoa569_RS04265
uniprot id: A0A5B8I7X6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

568768:Dpoa569 RS09520
gene id: 568768:Dpoa569_RS09520
uniprot id: A0A5B8I6D5
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS16705
gene id: 568768:Dpoa569_RS16705
uniprot id: A0A5B8HQN3
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

568768:Dpoa569 RS01680
gene id: 568768:Dpoa569_RS01680
uniprot id: A0A5B8I175
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.

568768:Dpoa569 RS12735
gene id: 568768:Dpoa569_RS12735
uniprot id: A0A5B8I8D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

568768:Dpoa569 RS13245
gene id: 568768:Dpoa569_RS13245
uniprot id: A0A5B8HQA7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

568768:Dpoa569 RS01155
gene id: 568768:Dpoa569_RS01155
uniprot id: A0A5B8I0Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

568768:Dpoa569 RS05045
gene id: 568768:Dpoa569_RS05045
uniprot id: A0A5B8I5L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

568768:Dpoa569 RS18400
gene id: 568768:Dpoa569_RS18400
uniprot id: A0A5B8IJY6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

568768:Dpoa569 RS16240
gene id: 568768:Dpoa569_RS16240
uniprot id: A0A5B8HQE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

568768:Dpoa569 RS11265
gene id: 568768:Dpoa569_RS11265
uniprot id: A0A5B8HNS7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

568768:Dpoa569 RS13265
gene id: 568768:Dpoa569_RS13265
uniprot id: A0A5B8IFS4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

568768:Dpoa569 RS12920
gene id: 568768:Dpoa569_RS12920
uniprot id: A0A5B8I919
names: Similarity
messages: Belongs to the UPF0250 family.

568768:Dpoa569 RS01185
gene id: 568768:Dpoa569_RS01185
uniprot id: A0A5B8HFG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS15770
gene id: 568768:Dpoa569_RS15770
uniprot id: A0A5B8HS61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

568768:Dpoa569 RS10785
gene id: 568768:Dpoa569_RS10785
uniprot id: A0A5B8HNF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS10120
gene id: 568768:Dpoa569_RS10120
uniprot id: A0A5B8IBP2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

568768:Dpoa569 RS12840
gene id: 568768:Dpoa569_RS12840
uniprot id: A0A5B8IDI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS00090
gene id: 568768:Dpoa569_RS00090
uniprot id: A0A5B8HUM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

568768:Dpoa569 RS04105
gene id: 568768:Dpoa569_RS04105
uniprot id: A0A5B8HHV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

568768:Dpoa569 RS05890
gene id: 568768:Dpoa569_RS05890
uniprot id: A0A5B8I2M4
names: Similarity
messages: Belongs to the HypD family.

568768:Dpoa569 RS12895
gene id: 568768:Dpoa569_RS12895
uniprot id: A0A5B8IAF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

568768:Dpoa569 RS07525
gene id: 568768:Dpoa569_RS07525
uniprot id: A0A5B8I582
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LpoB family.
messages: Cell outer membrane
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

568768:Dpoa569 RS01025
gene id: 568768:Dpoa569_RS01025
uniprot id: A0A5B8HTL6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

568768:Dpoa569 RS12740
gene id: 568768:Dpoa569_RS12740
uniprot id: A0A5B8HMX2
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

568768:Dpoa569 RS07320
gene id: 568768:Dpoa569_RS07320
uniprot id: A0A5B8I546
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

568768:Dpoa569 RS12480
gene id: 568768:Dpoa569_RS12480
uniprot id: A0A5B8IF23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS01010
gene id: 568768:Dpoa569_RS01010
uniprot id: A0A5B8IET9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

568768:Dpoa569 RS05430
gene id: 568768:Dpoa569_RS05430
uniprot id: A0A5B8HJF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
messages: Cell inner membrane
messages: Component of an export pathway for enterobactin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

568768:Dpoa569 RS00110
gene id: 568768:Dpoa569_RS00110
uniprot id: A0A5Q2V5C1
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS07535
gene id: 568768:Dpoa569_RS07535
uniprot id: A0A5B8I591
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

568768:Dpoa569 RS18165
gene id: 568768:Dpoa569_RS18165
uniprot id: A0A5B8HTQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

568768:Dpoa569 RS15960
gene id: 568768:Dpoa569_RS15960
uniprot id: A0A5B8HRM0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

568768:Dpoa569 RS00900
gene id: 568768:Dpoa569_RS00900
uniprot id: A0A5B8I5S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

568768:Dpoa569 RS13000
gene id: 568768:Dpoa569_RS13000
uniprot id: A0A5B8IAI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

568768:Dpoa569 RS04815
gene id: 568768:Dpoa569_RS04815
uniprot id: A0A5B8I7W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS19250
gene id: 568768:Dpoa569_RS19250
uniprot id: A0A5B8ICN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

568768:Dpoa569 RS04015
gene id: 568768:Dpoa569_RS04015
uniprot id: A0A5B8I7R9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

568768:Dpoa569 RS11095
gene id: 568768:Dpoa569_RS11095
uniprot id: A0A5B8ICC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS00700
gene id: 568768:Dpoa569_RS00700
uniprot id: A0A5B8I0H3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS10640
gene id: 568768:Dpoa569_RS10640
uniprot id: A0A5B8HNE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

568768:Dpoa569 RS13205
gene id: 568768:Dpoa569_RS13205
uniprot id: A0A5B8IAN5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

568768:Dpoa569 RS10790
gene id: 568768:Dpoa569_RS10790
uniprot id: A0A5B8IDV6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

568768:Dpoa569 RS12700
gene id: 568768:Dpoa569_RS12700
uniprot id: A0A5B8IDF5
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS07090
gene id: 568768:Dpoa569_RS07090
uniprot id: A0A5B8I4Z5
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

568768:Dpoa569 RS02950
gene id: 568768:Dpoa569_RS02950
uniprot id: A0A5B8HFG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

568768:Dpoa569 RS16040
gene id: 568768:Dpoa569_RS16040
uniprot id: A0A5B8HQA3
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS02055
gene id: 568768:Dpoa569_RS02055
uniprot id: A0A5B8I1P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

568768:Dpoa569 RS09285
gene id: 568768:Dpoa569_RS09285
uniprot id: A0A5B8IBS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

568768:Dpoa569 RS00935
gene id: 568768:Dpoa569_RS00935
uniprot id: A0A5B8HFB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

568768:Dpoa569 RS09840
gene id: 568768:Dpoa569_RS09840
uniprot id: A0A5B8I6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

568768:Dpoa569 RS12625
gene id: 568768:Dpoa569_RS12625
uniprot id: A0A5B8I6V8
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

568768:Dpoa569 RS15565
gene id: 568768:Dpoa569_RS15565
uniprot id: A0A5B8IFE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

568768:Dpoa569 RS14455
gene id: 568768:Dpoa569_RS14455
uniprot id: A0A5B8HR89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

568768:Dpoa569 RS16835
gene id: 568768:Dpoa569_RS16835
uniprot id: A0A5B8HS15
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

568768:Dpoa569 RS13180
gene id: 568768:Dpoa569_RS13180
uniprot id: A0A5B8I978
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

568768:Dpoa569 RS02180
gene id: 568768:Dpoa569_RS02180
uniprot id: A0A5B8HEX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

568768:Dpoa569 RS10470
gene id: 568768:Dpoa569_RS10470
uniprot id: A0A5B8I733
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

568768:Dpoa569 RS12280
gene id: 568768:Dpoa569_RS12280
uniprot id: A0A5B8IEU2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

568768:Dpoa569 RS00945
gene id: 568768:Dpoa569_RS00945
uniprot id: A0A5B8I0M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

568768:Dpoa569 RS18035
gene id: 568768:Dpoa569_RS18035
uniprot id: A0A5B8IBS9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

568768:Dpoa569 RS01215
gene id: 568768:Dpoa569_RS01215
uniprot id: A0A5B8HZ57
names: Similarity
messages: Belongs to the GARS family.

568768:Dpoa569 RS13340
gene id: 568768:Dpoa569_RS13340
uniprot id: A0A5B8HNF2
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

568768:Dpoa569 RS18545
gene id: 568768:Dpoa569_RS18545
uniprot id: A0A5B8IC43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

568768:Dpoa569 RS18220
gene id: 568768:Dpoa569_RS18220
uniprot id: A0A5B8IJN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

568768:Dpoa569 RS10825
gene id: 568768:Dpoa569_RS10825
uniprot id: A0A5B8IC59
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS17380
gene id: 568768:Dpoa569_RS17380
uniprot id: A0A5B8IB21
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family. AlsE subfamily.
messages: Catalyzes the reversible epimerization of D-allulose 6-phosphate to D-fructose 6-phosphate. Can also catalyze with lower efficiency the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

568768:Dpoa569 RS03230
gene id: 568768:Dpoa569_RS03230
uniprot id: A0A5B8HFP5
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

568768:Dpoa569 RS01945
gene id: 568768:Dpoa569_RS01945
uniprot id: A0A5B8HEK6
names: Similarity
messages: Belongs to the phosphoribulokinase family.

568768:Dpoa569 RS03195
gene id: 568768:Dpoa569_RS03195
uniprot id: A0A5B8I7A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N-Me-Phe pilin family.
messages: Membrane

568768:Dpoa569 RS07605
gene id: 568768:Dpoa569_RS07605
uniprot id: A0A5B8HKM2
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family. NagK subfamily.
messages: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.

568768:Dpoa569 RS15470
gene id: 568768:Dpoa569_RS15470
uniprot id: A0A5B8IC58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS10060
gene id: 568768:Dpoa569_RS10060
uniprot id: A0A5B8HKI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

568768:Dpoa569 RS02390
gene id: 568768:Dpoa569_RS02390
uniprot id: A0A5B8I6S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

568768:Dpoa569 RS01705
gene id: 568768:Dpoa569_RS01705
uniprot id: A0A5B8I5W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

568768:Dpoa569 RS04300
gene id: 568768:Dpoa569_RS04300
uniprot id: A0A5B8I7L1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

568768:Dpoa569 RS16485
gene id: 568768:Dpoa569_RS16485
uniprot id: A0A5B8II45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

568768:Dpoa569 RS10280
gene id: 568768:Dpoa569_RS10280
uniprot id: A0A5B8IBS8
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

568768:Dpoa569 RS02410
gene id: 568768:Dpoa569_RS02410
uniprot id: A0A5B8I1V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

568768:Dpoa569 RS03925
gene id: 568768:Dpoa569_RS03925
uniprot id: A0A5B8I174
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

568768:Dpoa569 RS10805
gene id: 568768:Dpoa569_RS10805
uniprot id: A0A5B8I7G7
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

568768:Dpoa569 RS01895
gene id: 568768:Dpoa569_RS01895
uniprot id: A0A5B8HZP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS13765
gene id: 568768:Dpoa569_RS13765
uniprot id: A0A5B8I7N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

568768:Dpoa569 RS07245
gene id: 568768:Dpoa569_RS07245
uniprot id: A0A5B8I530
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

568768:Dpoa569 RS09210
gene id: 568768:Dpoa569_RS09210
uniprot id: A0A5B8I814
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

568768:Dpoa569 RS19000
gene id: 568768:Dpoa569_RS19000
uniprot id: A0A5B8HUA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

568768:Dpoa569 RS04060
gene id: 568768:Dpoa569_RS04060
uniprot id: A0A5B8HIF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

568768:Dpoa569 RS05895
gene id: 568768:Dpoa569_RS05895
uniprot id: A0A5B8I4B4
names: Similarity
messages: Belongs to the HypE family.

568768:Dpoa569 RS16715
gene id: 568768:Dpoa569_RS16715
uniprot id: A0A5B8IIC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

568768:Dpoa569 RS07750
gene id: 568768:Dpoa569_RS07750
uniprot id: A0A5B8I5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

568768:Dpoa569 RS09035
gene id: 568768:Dpoa569_RS09035
uniprot id: A0A5B8HM10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

568768:Dpoa569 RS01555
gene id: 568768:Dpoa569_RS01555
uniprot id: A0A5B8HED1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

568768:Dpoa569 RS04765
gene id: 568768:Dpoa569_RS04765
uniprot id: A0A5B8HIY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

568768:Dpoa569 RS11270
gene id: 568768:Dpoa569_RS11270
uniprot id: A0A5B8IE66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS12310
gene id: 568768:Dpoa569_RS12310
uniprot id: A0A5B8HPP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

568768:Dpoa569 RS07910
gene id: 568768:Dpoa569_RS07910
uniprot id: A0A5B8IBV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

568768:Dpoa569 RS10965
gene id: 568768:Dpoa569_RS10965
uniprot id: A0A5B8I7C6
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: To H.influenzae HI_0842.

568768:Dpoa569 RS17210
gene id: 568768:Dpoa569_RS17210
uniprot id: A0A5B8HQZ3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

568768:Dpoa569 RS03675
gene id: 568768:Dpoa569_RS03675
uniprot id: A0A5B8HFZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

568768:Dpoa569 RS13485
gene id: 568768:Dpoa569_RS13485
uniprot id: A0A5B8I7E9
names: Similarity
messages: Belongs to the UPF0234 family.

568768:Dpoa569 RS15360
gene id: 568768:Dpoa569_RS15360
uniprot id: A0A5B8IHC3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS13005
gene id: 568768:Dpoa569_RS13005
uniprot id: A0A5B8HPW4
names: Subcellular Location Annotation
messages: Cytoplasm

568768:Dpoa569 RS01835
gene id: 568768:Dpoa569_RS01835
uniprot id: A0A5B8HZN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

568768:Dpoa569 RS17765
gene id: 568768:Dpoa569_RS17765
uniprot id: A0A5B8IJE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

568768:Dpoa569 RS03970
gene id: 568768:Dpoa569_RS03970
uniprot id: A0A5B8I321
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

568768:Dpoa569 RS13900
gene id: 568768:Dpoa569_RS13900
uniprot id: A0A5B8HQV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

568768:Dpoa569 RS16215
gene id: 568768:Dpoa569_RS16215
uniprot id: A0A5B8IB18
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

568768:Dpoa569 RS03150
gene id: 568768:Dpoa569_RS03150
uniprot id: A0A5B8I2E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecM family.
messages: Periplasm
messages: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
messages: cytosol

568768:Dpoa569 RS13230
gene id: 568768:Dpoa569_RS13230
uniprot id: A0A5B8I989
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

568768:Dpoa569 RS12745
gene id: 568768:Dpoa569_RS12745
uniprot id: A0A5B8HPY8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS16925
gene id: 568768:Dpoa569_RS16925
uniprot id: A0A5B8HQT7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

568768:Dpoa569 RS10875
gene id: 568768:Dpoa569_RS10875
uniprot id: A0A5B8HLD8
names: Similarity
messages: Belongs to the elongation factor P family.

568768:Dpoa569 RS03100
gene id: 568768:Dpoa569_RS03100
uniprot id: A0A5B8I2C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS12935
gene id: 568768:Dpoa569_RS12935
uniprot id: A0A5B8HN26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

568768:Dpoa569 RS13980
gene id: 568768:Dpoa569_RS13980
uniprot id: A0A5B8I9D6
names: Similarity
messages: Belongs to the SufE family.

568768:Dpoa569 RS15085
gene id: 568768:Dpoa569_RS15085
uniprot id: A0A5B8HR52
names: Similarity
messages: Belongs to the thioredoxin family.

568768:Dpoa569 RS13570
gene id: 568768:Dpoa569_RS13570
uniprot id: A0A5B8HQ94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

568768:Dpoa569 RS08475
gene id: 568768:Dpoa569_RS08475
uniprot id: A0A5B8I5R7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS15820
gene id: 568768:Dpoa569_RS15820
uniprot id: A0A5B8IA56
names: Similarity
messages: Belongs to the VapB family.

568768:Dpoa569 RS12495
gene id: 568768:Dpoa569_RS12495
uniprot id: A0A5B8I8N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

568768:Dpoa569 RS08655
gene id: 568768:Dpoa569_RS08655
uniprot id: A0A5B8HLT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS09750
gene id: 568768:Dpoa569_RS09750
uniprot id: A0A5B8I509
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

568768:Dpoa569 RS16470
gene id: 568768:Dpoa569_RS16470
uniprot id: A0A5B8IAL4
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

568768:Dpoa569 RS09670
gene id: 568768:Dpoa569_RS09670
uniprot id: A0A5B8I8B6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.
messages: Homohexamer.

568768:Dpoa569 RS08060
gene id: 568768:Dpoa569_RS08060
uniprot id: A0A5B8I7E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS18375
gene id: 568768:Dpoa569_RS18375
uniprot id: A0A5B8HTW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

568768:Dpoa569 RS19340
gene id: 568768:Dpoa569_RS19340
uniprot id: A0A5B8IEP0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS03180
gene id: 568768:Dpoa569_RS03180
uniprot id: A0A5B8I2N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

568768:Dpoa569 RS03585
gene id: 568768:Dpoa569_RS03585
uniprot id: A0A5B8I2S7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
messages: In the N-terminal section; belongs to the 2-acyl-GPE acetyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.

568768:Dpoa569 RS02005
gene id: 568768:Dpoa569_RS02005
uniprot id: A0A5B8I1M0
names: Similarity
messages: Belongs to the SlyX family.

568768:Dpoa569 RS01605
gene id: 568768:Dpoa569_RS01605
uniprot id: A0A5B8HEE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

568768:Dpoa569 RS04050
gene id: 568768:Dpoa569_RS04050
uniprot id: A0A5B8I7D8
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

568768:Dpoa569 RS13655
gene id: 568768:Dpoa569_RS13655
uniprot id: A0A5B8I8Z1
names: Similarity
messages: Belongs to the asparaginase 1 family.

568768:Dpoa569 RS13885
gene id: 568768:Dpoa569_RS13885
uniprot id: A0A5B8I7Q9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS03015
gene id: 568768:Dpoa569_RS03015
uniprot id: A0A5B8I6Q1
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

568768:Dpoa569 RS07455
gene id: 568768:Dpoa569_RS07455
uniprot id: A0A5B8I6X7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

568768:Dpoa569 RS13060
gene id: 568768:Dpoa569_RS13060
uniprot id: A0A5B8IFL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

568768:Dpoa569 RS05610
gene id: 568768:Dpoa569_RS05610
uniprot id: A0A5B8HJJ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

568768:Dpoa569 RS18655
gene id: 568768:Dpoa569_RS18655
uniprot id: A0A5B8IAV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

568768:Dpoa569 RS00040
gene id: 568768:Dpoa569_RS00040
uniprot id: A0A5B8HUL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

568768:Dpoa569 RS12610
gene id: 568768:Dpoa569_RS12610
uniprot id: A0A5B8HPQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

568768:Dpoa569 RS09170
gene id: 568768:Dpoa569_RS09170
uniprot id: A0A5B8ILH9
names: Similarity
messages: Belongs to the UPF0181 family.

568768:Dpoa569 RS01180
gene id: 568768:Dpoa569_RS01180
uniprot id: A0A5B8IL07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

568768:Dpoa569 RS08140
gene id: 568768:Dpoa569_RS08140
uniprot id: A0A5B8I5M8
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS11290
gene id: 568768:Dpoa569_RS11290
uniprot id: A0A5B8I7V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS09855
gene id: 568768:Dpoa569_RS09855
uniprot id: A0A5B8I6L2
names: Similarity
messages: Belongs to the UPF0263 family.

568768:Dpoa569 RS18150
gene id: 568768:Dpoa569_RS18150
uniprot id: A0A5B8ICA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS02480
gene id: 568768:Dpoa569_RS02480
uniprot id: A0A5B8I6B9
names: Subcellular Location Annotation
messages: Cell inner membrane

568768:Dpoa569 RS05820
gene id: 568768:Dpoa569_RS05820
uniprot id: A0A5B8I615
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

568768:Dpoa569 RS03590
gene id: 568768:Dpoa569_RS03590
uniprot id: A0A5B8I0X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
messages: Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS03635
gene id: 568768:Dpoa569_RS03635
uniprot id: A0A5B8IDC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Monomer.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

568768:Dpoa569 RS16425
gene id: 568768:Dpoa569_RS16425
uniprot id: A0A5B8ICU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

568768:Dpoa569 RS04725
gene id: 568768:Dpoa569_RS04725
uniprot id: A0A5B8I3J2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

568768:Dpoa569 RS16680
gene id: 568768:Dpoa569_RS16680
uniprot id: A0A5B8ILV6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

568768:Dpoa569 RS16560
gene id: 568768:Dpoa569_RS16560
uniprot id: A0A5B8IAT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

568768:Dpoa569 RS02165
gene id: 568768:Dpoa569_RS02165
uniprot id: A0A5B8HZV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

568768:Dpoa569 RS16210
gene id: 568768:Dpoa569_RS16210
uniprot id: A0A5B8I987
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS08625
gene id: 568768:Dpoa569_RS08625
uniprot id: A0A5B8I5V3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

568768:Dpoa569 RS16730
gene id: 568768:Dpoa569_RS16730
uniprot id: A0A5B8IIC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

568768:Dpoa569 RS04450
gene id: 568768:Dpoa569_RS04450
uniprot id: A0A5B8HIN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

568768:Dpoa569 RS09585
gene id: 568768:Dpoa569_RS09585
uniprot id: A0A5B8ILG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS18805
gene id: 568768:Dpoa569_RS18805
uniprot id: A0A5B8IKB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS03005
gene id: 568768:Dpoa569_RS03005
uniprot id: A0A5B8HFI2
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

568768:Dpoa569 RS02195
gene id: 568768:Dpoa569_RS02195
uniprot id: A0A5B8I1T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

568768:Dpoa569 RS04315
gene id: 568768:Dpoa569_RS04315
uniprot id: A0A5B8I7Y7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS03115
gene id: 568768:Dpoa569_RS03115
uniprot id: A0A5B8HH24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

568768:Dpoa569 RS11590
gene id: 568768:Dpoa569_RS11590
uniprot id: A0A5B8HP06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Periplasm

568768:Dpoa569 RS03905
gene id: 568768:Dpoa569_RS03905
uniprot id: A0A5B8I362
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

568768:Dpoa569 RS07655
gene id: 568768:Dpoa569_RS07655
uniprot id: A0A5B8HIT1
names: Similarity
messages: Belongs to the YkuD family.

568768:Dpoa569 RS10700
gene id: 568768:Dpoa569_RS10700
uniprot id: A0A5B8HNF5
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

568768:Dpoa569 RS00510
gene id: 568768:Dpoa569_RS00510
uniprot id: A0A5B8I0D2
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS08395
gene id: 568768:Dpoa569_RS08395
uniprot id: A0A5B8I7K0
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS04120
gene id: 568768:Dpoa569_RS04120
uniprot id: A0A5B8HIH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

568768:Dpoa569 RS18310
gene id: 568768:Dpoa569_RS18310
uniprot id: A0A5B8ICF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

568768:Dpoa569 RS16545
gene id: 568768:Dpoa569_RS16545
uniprot id: A0A5B8ICW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

568768:Dpoa569 RS18810
gene id: 568768:Dpoa569_RS18810
uniprot id: A0A5B8ICB4
names: Similarity
messages: Belongs to the peptidase S58 family.

568768:Dpoa569 RS09415
gene id: 568768:Dpoa569_RS09415
uniprot id: A0A5B8HK06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

568768:Dpoa569 RS18065
gene id: 568768:Dpoa569_RS18065
uniprot id: A0A5B8HTL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoA family.
messages: Interacts with PBP1a.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).

568768:Dpoa569 RS05695
gene id: 568768:Dpoa569_RS05695
uniprot id: A0A5B8I419
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

568768:Dpoa569 RS05940
gene id: 568768:Dpoa569_RS05940
uniprot id: A0A5B8IAD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

568768:Dpoa569 RS12615
gene id: 568768:Dpoa569_RS12615
uniprot id: A0A5B8IF54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

568768:Dpoa569 RS05345
gene id: 568768:Dpoa569_RS05345
uniprot id: A0A5B8HGZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

568768:Dpoa569 RS08530
gene id: 568768:Dpoa569_RS08530
uniprot id: A0A5B8HJH3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS04645
gene id: 568768:Dpoa569_RS04645
uniprot id: A0A5B8HGJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS02865
gene id: 568768:Dpoa569_RS02865
uniprot id: A0A5B8I2E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

568768:Dpoa569 RS18260
gene id: 568768:Dpoa569_RS18260
uniprot id: A0A5B8HRK1
names: Similarity
messages: Belongs to the UPF0307 family.

568768:Dpoa569 RS17890
gene id: 568768:Dpoa569_RS17890
uniprot id: A0A5B8IBD0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

568768:Dpoa569 RS19360
gene id: 568768:Dpoa569_RS19360
uniprot id: A0A5B8IBB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

568768:Dpoa569 RS18205
gene id: 568768:Dpoa569_RS18205
uniprot id: A0A5B8IBL2
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

568768:Dpoa569 RS04735
gene id: 568768:Dpoa569_RS04735
uniprot id: A0A5B8I3K6
names: Similarity
messages: Belongs to the YfgM family.

568768:Dpoa569 RS08045
gene id: 568768:Dpoa569_RS08045
uniprot id: A0A5B8HJ43
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
messages: Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.

568768:Dpoa569 RS05080
gene id: 568768:Dpoa569_RS05080
uniprot id: A0A5B8HGS4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS17530
gene id: 568768:Dpoa569_RS17530
uniprot id: A0A5B8HSD1
names: Similarity
messages: Belongs to the cytochrome P450 family.

568768:Dpoa569 RS00760
gene id: 568768:Dpoa569_RS00760
uniprot id: A0A5B8HF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS02050
gene id: 568768:Dpoa569_RS02050
uniprot id: A0A5B8I6J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

568768:Dpoa569 RS10540
gene id: 568768:Dpoa569_RS10540
uniprot id: A0A5B8IBZ3
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

568768:Dpoa569 RS06260
gene id: 568768:Dpoa569_RS06260
uniprot id: A0A5B8HJJ4
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS12140
gene id: 568768:Dpoa569_RS12140
uniprot id: A0A5B8HMG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS18060
gene id: 568768:Dpoa569_RS18060
uniprot id: A0A5B8HRF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

568768:Dpoa569 RS07375
gene id: 568768:Dpoa569_RS07375
uniprot id: A0A5B8I510
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

568768:Dpoa569 RS06925
gene id: 568768:Dpoa569_RS06925
uniprot id: A0A5B8I9H3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

568768:Dpoa569 RS03965
gene id: 568768:Dpoa569_RS03965
uniprot id: A0A5B8I7Q7
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

568768:Dpoa569 RS02605
gene id: 568768:Dpoa569_RS02605
uniprot id: A0A5B8HGJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

568768:Dpoa569 RS09590
gene id: 568768:Dpoa569_RS09590
uniprot id: A0A5B8HK49
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

568768:Dpoa569 RS02920
gene id: 568768:Dpoa569_RS02920
uniprot id: A0A5B8HHE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

568768:Dpoa569 RS12070
gene id: 568768:Dpoa569_RS12070
uniprot id: A0A5B8I819
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

568768:Dpoa569 RS17950
gene id: 568768:Dpoa569_RS17950
uniprot id: A0A5B8HTI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

568768:Dpoa569 RS17730
gene id: 568768:Dpoa569_RS17730
uniprot id: A0A5B8IBX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

568768:Dpoa569 RS05685
gene id: 568768:Dpoa569_RS05685
uniprot id: A0A5B8I2H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

568768:Dpoa569 RS14125
gene id: 568768:Dpoa569_RS14125
uniprot id: A0A5B8HP28
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

568768:Dpoa569 RS00580
gene id: 568768:Dpoa569_RS00580
uniprot id: A0A5B8I0K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

568768:Dpoa569 RS07070
gene id: 568768:Dpoa569_RS07070
uniprot id: A0A5B8I9K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

568768:Dpoa569 RS02565
gene id: 568768:Dpoa569_RS02565
uniprot id: A0A5B8I230
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

568768:Dpoa569 RS18635
gene id: 568768:Dpoa569_RS18635
uniprot id: A0A5B8HT07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

568768:Dpoa569 RS09525
gene id: 568768:Dpoa569_RS09525
uniprot id: A0A5B8HK38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

568768:Dpoa569 RS19140
gene id: 568768:Dpoa569_RS19140
uniprot id: A0A5B8IB61
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS18385
gene id: 568768:Dpoa569_RS18385
uniprot id: A0A5B8IE27
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

568768:Dpoa569 RS04760
gene id: 568768:Dpoa569_RS04760
uniprot id: A0A5B8I5E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

568768:Dpoa569 RS03370
gene id: 568768:Dpoa569_RS03370
uniprot id: A0A5B8I2M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS15730
gene id: 568768:Dpoa569_RS15730
uniprot id: A0A5B8ICC6
names: Subunit
messages: Homodimer.

568768:Dpoa569 RS05120
gene id: 568768:Dpoa569_RS05120
uniprot id: A0A5B8I3U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS14905
gene id: 568768:Dpoa569_RS14905
uniprot id: A0A5B8IA76
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

568768:Dpoa569 RS02150
gene id: 568768:Dpoa569_RS02150
uniprot id: A0A5B8HER6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

568768:Dpoa569 RS09000
gene id: 568768:Dpoa569_RS09000
uniprot id: A0A5B8ICM2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

568768:Dpoa569 RS12355
gene id: 568768:Dpoa569_RS12355
uniprot id: A0A5B8HML4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

568768:Dpoa569 RS11930
gene id: 568768:Dpoa569_RS11930
uniprot id: A0A5B8I9W4
names: Similarity
messages: Belongs to the peptidase A31 family.

568768:Dpoa569 RS13420
gene id: 568768:Dpoa569_RS13420
uniprot id: A0A5B8IFW3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

568768:Dpoa569 RS04295
gene id: 568768:Dpoa569_RS04295
uniprot id: A0A5B8HI07
names: Similarity
messages: Belongs to the SfsA family.

568768:Dpoa569 RS02780
gene id: 568768:Dpoa569_RS02780
uniprot id: A0A5B8I0B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

568768:Dpoa569 RS01340
gene id: 568768:Dpoa569_RS01340
uniprot id: A0A5B8I145
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

568768:Dpoa569 RS11285
gene id: 568768:Dpoa569_RS11285
uniprot id: A0A5B8ID29
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

568768:Dpoa569 RS04925
gene id: 568768:Dpoa569_RS04925
uniprot id: A0A5B8I5I9
names: Similarity
messages: Belongs to the acylphosphatase family.

568768:Dpoa569 RS16630
gene id: 568768:Dpoa569_RS16630
uniprot id: A0A5B8IBA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

568768:Dpoa569 RS02415
gene id: 568768:Dpoa569_RS02415
uniprot id: A0A5B8HF20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

568768:Dpoa569 RS16185
gene id: 568768:Dpoa569_RS16185
uniprot id: A0A5B8IHW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Membrane
messages: Transports acetate.

568768:Dpoa569 RS05900
gene id: 568768:Dpoa569_RS05900
uniprot id: A0A5B8I470
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

568768:Dpoa569 RS16750
gene id: 568768:Dpoa569_RS16750
uniprot id: A0A5B8IAQ8
names: Similarity
messages: Belongs to the mannitol dehydrogenase family. UxaB subfamily.

568768:Dpoa569 RS17340
gene id: 568768:Dpoa569_RS17340
uniprot id: A0A5B8IDD7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

568768:Dpoa569 RS07600
gene id: 568768:Dpoa569_RS07600
uniprot id: A0A5B8HIR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

568768:Dpoa569 RS00660
gene id: 568768:Dpoa569_RS00660
uniprot id: A0A5B8HF37
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

568768:Dpoa569 RS11715
gene id: 568768:Dpoa569_RS11715
uniprot id: A0A5B8I6B0
names: Similarity
messages: Belongs to the IucA/IucC family.

568768:Dpoa569 RS16380
gene id: 568768:Dpoa569_RS16380
uniprot id: A0A5B8HRS7
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

568768:Dpoa569 RS08015
gene id: 568768:Dpoa569_RS08015
uniprot id: A0A5B8HL25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

568768:Dpoa569 RS03875
gene id: 568768:Dpoa569_RS03875
uniprot id: A0A5B8I2V1
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS09770
gene id: 568768:Dpoa569_RS09770
uniprot id: A0A5B8IBF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

568768:Dpoa569 RS00540
gene id: 568768:Dpoa569_RS00540
uniprot id: A0A5B8I0D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS17205
gene id: 568768:Dpoa569_RS17205
uniprot id: A0A5B8IAY8
names: Similarity
messages: Belongs to the Smp family.

568768:Dpoa569 RS07610
gene id: 568768:Dpoa569_RS07610
uniprot id: A0A5B8IA13
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-90 and Arg-93) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form.

568768:Dpoa569 RS13055
gene id: 568768:Dpoa569_RS13055
uniprot id: A0A5B8HPY0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

568768:Dpoa569 RS09960
gene id: 568768:Dpoa569_RS09960
uniprot id: A0A5B8HKF6
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

568768:Dpoa569 RS01720
gene id: 568768:Dpoa569_RS01720
uniprot id: A0A5B8I6C0
names: Similarity
messages: Belongs to the DapA family.

568768:Dpoa569 RS17360
gene id: 568768:Dpoa569_RS17360
uniprot id: A0A5B8IBD3
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

568768:Dpoa569 RS15300
gene id: 568768:Dpoa569_RS15300
uniprot id: A0A5B8HR87
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

568768:Dpoa569 RS10445
gene id: 568768:Dpoa569_RS10445
uniprot id: A0A5B8HN64
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

568768:Dpoa569 RS02620
gene id: 568768:Dpoa569_RS02620
uniprot id: A0A5B8I074
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

568768:Dpoa569 RS03765
gene id: 568768:Dpoa569_RS03765
uniprot id: A0A5B8I2X3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

568768:Dpoa569 RS11275
gene id: 568768:Dpoa569_RS11275
uniprot id: A0A5B8I7J9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

568768:Dpoa569 RS11260
gene id: 568768:Dpoa569_RS11260
uniprot id: A0A5B8I9H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

568768:Dpoa569 RS02770
gene id: 568768:Dpoa569_RS02770
uniprot id: A0A5B8I709
names: Similarity
messages: Belongs to the threonine synthase family.

568768:Dpoa569 RS11755
gene id: 568768:Dpoa569_RS11755
uniprot id: A0A5B8I9T0
names: Caution
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS00045
gene id: 568768:Dpoa569_RS00045
uniprot id: A0A5B8IKT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family. RNase BN subfamily.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.

568768:Dpoa569 RS05690
gene id: 568768:Dpoa569_RS05690
uniprot id: A0A5B8I464
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS12265
gene id: 568768:Dpoa569_RS12265
uniprot id: A0A5B8ID67
names: Similarity
messages: Belongs to the UDPGP type 2 family.

568768:Dpoa569 RS12595
gene id: 568768:Dpoa569_RS12595
uniprot id: A0A5B8HPV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

568768:Dpoa569 RS05645
gene id: 568768:Dpoa569_RS05645
uniprot id: A0A5B8I408
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

568768:Dpoa569 RS17295
gene id: 568768:Dpoa569_RS17295
uniprot id: A0A5B8IBC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS01350
gene id: 568768:Dpoa569_RS01350
uniprot id: A0A5B8I0Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

568768:Dpoa569 RS03065
gene id: 568768:Dpoa569_RS03065
uniprot id: A0A5B8HH12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlaE exporter family.
messages: Cell inner membrane
messages: Exports L-alanine.

568768:Dpoa569 RS09615
gene id: 568768:Dpoa569_RS09615
uniprot id: A0A5B8HU28
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

568768:Dpoa569 RS00380
gene id: 568768:Dpoa569_RS00380
uniprot id: A0A5B8I0A3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

568768:Dpoa569 RS07115
gene id: 568768:Dpoa569_RS07115
uniprot id: A0A5B8HK07
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

568768:Dpoa569 RS02045
gene id: 568768:Dpoa569_RS02045
uniprot id: A0A5B8HEN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrH/TusB family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

568768:Dpoa569 RS14890
gene id: 568768:Dpoa569_RS14890
uniprot id: A0A5B8IGX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

568768:Dpoa569 RS09965
gene id: 568768:Dpoa569_RS09965
uniprot id: A0A5B8HMS8
names: Similarity
messages: Belongs to the peptidase S49 family.

568768:Dpoa569 RS04465
gene id: 568768:Dpoa569_RS04465
uniprot id: A0A5B8I1J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

568768:Dpoa569 RS00890
gene id: 568768:Dpoa569_RS00890
uniprot id: A0A5B8I0L2
names: Similarity
messages: Belongs to the agmatine deiminase family.

568768:Dpoa569 RS15615
gene id: 568768:Dpoa569_RS15615
uniprot id: A0A5B8IFF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

568768:Dpoa569 RS07505
gene id: 568768:Dpoa569_RS07505
uniprot id: A0A5B8I6Y9
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS01295
gene id: 568768:Dpoa569_RS01295
uniprot id: A0A5B8HZ70
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

568768:Dpoa569 RS16845
gene id: 568768:Dpoa569_RS16845
uniprot id: A0A5B8IAY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Monomer.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

568768:Dpoa569 RS02700
gene id: 568768:Dpoa569_RS02700
uniprot id: A0A5B8I6H2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS18325
gene id: 568768:Dpoa569_RS18325
uniprot id: A0A5B8HTU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

568768:Dpoa569 RS05330
gene id: 568768:Dpoa569_RS05330
uniprot id: A0A5B8I2A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.
messages: Membrane

568768:Dpoa569 RS09335
gene id: 568768:Dpoa569_RS09335
uniprot id: A0A5B8ICU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

568768:Dpoa569 RS05705
gene id: 568768:Dpoa569_RS05705
uniprot id: A0A5B8HJ48
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

568768:Dpoa569 RS05315
gene id: 568768:Dpoa569_RS05315
uniprot id: A0A5B8HJC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane
messages: Type II secretion system is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. Forms homomultimers.

568768:Dpoa569 RS03135
gene id: 568768:Dpoa569_RS03135
uniprot id: A0A5B8I792
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

568768:Dpoa569 RS13195
gene id: 568768:Dpoa569_RS13195
uniprot id: A0A5B8HQ87
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

568768:Dpoa569 RS15640
gene id: 568768:Dpoa569_RS15640
uniprot id: A0A5B8I8Y3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

568768:Dpoa569 RS03975
gene id: 568768:Dpoa569_RS03975
uniprot id: A0A5B8I190
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS17255
gene id: 568768:Dpoa569_RS17255
uniprot id: A0A5B8IBN6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

568768:Dpoa569 RS15180
gene id: 568768:Dpoa569_RS15180
uniprot id: A0A5B8IH60
names: Subcellular Location Annotation
messages: Cytoplasm

568768:Dpoa569 RS08235
gene id: 568768:Dpoa569_RS08235
uniprot id: A0A5B8I7H7
names: Similarity
messages: Belongs to the peptidase S1B family.

568768:Dpoa569 RS05400
gene id: 568768:Dpoa569_RS05400
uniprot id: A0A5B8I3U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

568768:Dpoa569 RS05020
gene id: 568768:Dpoa569_RS05020
uniprot id: A0A5B8I3S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS01065
gene id: 568768:Dpoa569_RS01065
uniprot id: A0A5B8HFD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

568768:Dpoa569 RS02325
gene id: 568768:Dpoa569_RS02325
uniprot id: A0A5B8HEV4
names: Similarity
messages: Belongs to the malate synthase family.

568768:Dpoa569 RS08485
gene id: 568768:Dpoa569_RS08485
uniprot id: A0A5B8HLA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.

568768:Dpoa569 RS09885
gene id: 568768:Dpoa569_RS09885
uniprot id: A0A5B8ID74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS08910
gene id: 568768:Dpoa569_RS08910
uniprot id: A0A5B8IF70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

568768:Dpoa569 RS11830
gene id: 568768:Dpoa569_RS11830
uniprot id: A0A5B8IEK2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: 4-aminobutanal can spontaneously cyclize to 1-pyrroline, and 5-aminopentanal to 1-piperideine.
messages: Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
messages: Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
messages: Homotetramer.

568768:Dpoa569 RS13220
gene id: 568768:Dpoa569_RS13220
uniprot id: A0A5B8I8Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

568768:Dpoa569 RS07630
gene id: 568768:Dpoa569_RS07630
uniprot id: A0A5B8I5A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

568768:Dpoa569 RS16735
gene id: 568768:Dpoa569_RS16735
uniprot id: A0A5B8IAW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

568768:Dpoa569 RS11860
gene id: 568768:Dpoa569_RS11860
uniprot id: A0A5B8I7U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS13845
gene id: 568768:Dpoa569_RS13845
uniprot id: A0A5B8HNV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

568768:Dpoa569 RS11610
gene id: 568768:Dpoa569_RS11610
uniprot id: A0A5B8I824
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

568768:Dpoa569 RS04665
gene id: 568768:Dpoa569_RS04665
uniprot id: A0A5B8HIU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

568768:Dpoa569 RS08230
gene id: 568768:Dpoa569_RS08230
uniprot id: A0A5B8IAE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

568768:Dpoa569 RS09905
gene id: 568768:Dpoa569_RS09905
uniprot id: A0A5B8HKD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

568768:Dpoa569 RS03705
gene id: 568768:Dpoa569_RS03705
uniprot id: A0A5B8I2V6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

568768:Dpoa569 RS00030
gene id: 568768:Dpoa569_RS00030
uniprot id: A0A5B8ICF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

568768:Dpoa569 RS13820
gene id: 568768:Dpoa569_RS13820
uniprot id: A0A5B8IG73
names: Subcellular Location Annotation
messages: Cytoplasm

568768:Dpoa569 RS05540
gene id: 568768:Dpoa569_RS05540
uniprot id: A0A5B8HJ00
names: Similarity
messages: Belongs to the UPF0115 family.

568768:Dpoa569 RS04505
gene id: 568768:Dpoa569_RS04505
uniprot id: A0A5B8I826
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

568768:Dpoa569 RS05010
gene id: 568768:Dpoa569_RS05010
uniprot id: A0A5B8I3Q6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

568768:Dpoa569 RS03090
gene id: 568768:Dpoa569_RS03090
uniprot id: A0A5B8I2F0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS02835
gene id: 568768:Dpoa569_RS02835
uniprot id: A0A5B8I0C7
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

568768:Dpoa569 RS18225
gene id: 568768:Dpoa569_RS18225
uniprot id: A0A5B8IDY3
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

568768:Dpoa569 RS05805
gene id: 568768:Dpoa569_RS05805
uniprot id: A0A5B8HHE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

568768:Dpoa569 RS07830
gene id: 568768:Dpoa569_RS07830
uniprot id: A0A5B8HKT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

568768:Dpoa569 RS00620
gene id: 568768:Dpoa569_RS00620
uniprot id: A0A5B8HDS8
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS10335
gene id: 568768:Dpoa569_RS10335
uniprot id: A0A5B8I8V4
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

568768:Dpoa569 RS06910
gene id: 568768:Dpoa569_RS06910
uniprot id: A0A5B8I4V0
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

568768:Dpoa569 RS15440
gene id: 568768:Dpoa569_RS15440
uniprot id: A0A5B8IAI7
names: Similarity
messages: Belongs to the MipA/OmpV family.

568768:Dpoa569 RS03390
gene id: 568768:Dpoa569_RS03390
uniprot id: A0A5B8HFT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

568768:Dpoa569 RS01135
gene id: 568768:Dpoa569_RS01135
uniprot id: A0A5B8I5L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

568768:Dpoa569 RS14930
gene id: 568768:Dpoa569_RS14930
uniprot id: A0A5B8IBU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

568768:Dpoa569 RS12980
gene id: 568768:Dpoa569_RS12980
uniprot id: A0A5B8I8I8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

568768:Dpoa569 RS09130
gene id: 568768:Dpoa569_RS09130
uniprot id: A0A5B8I635
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS17935
gene id: 568768:Dpoa569_RS17935
uniprot id: A0A5B8IC20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm
messages: Homotetramer.

568768:Dpoa569 RS02430
gene id: 568768:Dpoa569_RS02430
uniprot id: A0A5B8I1Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

568768:Dpoa569 RS01655
gene id: 568768:Dpoa569_RS01655
uniprot id: A0A5B8I158
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS04085
gene id: 568768:Dpoa569_RS04085
uniprot id: A0A5B8I1C0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

568768:Dpoa569 RS05625
gene id: 568768:Dpoa569_RS05625
uniprot id: A0A5B8I453
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS18350
gene id: 568768:Dpoa569_RS18350
uniprot id: A0A5B8IC11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

568768:Dpoa569 RS16520
gene id: 568768:Dpoa569_RS16520
uniprot id: A0A5B8IAM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

568768:Dpoa569 RS03560
gene id: 568768:Dpoa569_RS03560
uniprot id: A0A5B8HHC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

568768:Dpoa569 RS19010
gene id: 568768:Dpoa569_RS19010
uniprot id: A0A5B8IEG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

568768:Dpoa569 RS10140
gene id: 568768:Dpoa569_RS10140
uniprot id: A0A5B8I6T3
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

568768:Dpoa569 RS02615
gene id: 568768:Dpoa569_RS02615
uniprot id: A0A5B8I241
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

568768:Dpoa569 RS05790
gene id: 568768:Dpoa569_RS05790
uniprot id: A0A5B8I2J7
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.

568768:Dpoa569 RS19395
gene id: 568768:Dpoa569_RS19395
uniprot id: A0A5B8HTH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

568768:Dpoa569 RS11350
gene id: 568768:Dpoa569_RS11350
uniprot id: A0A5B8I7W5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

568768:Dpoa569 RS05270
gene id: 568768:Dpoa569_RS05270
uniprot id: A0A5B8I8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

568768:Dpoa569 RS18370
gene id: 568768:Dpoa569_RS18370
uniprot id: A0A5B8HRN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

568768:Dpoa569 RS09340
gene id: 568768:Dpoa569_RS09340
uniprot id: A0A5B8I699
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

568768:Dpoa569 RS04875
gene id: 568768:Dpoa569_RS04875
uniprot id: A0A5B8I5H6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer and homodimer.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

568768:Dpoa569 RS10095
gene id: 568768:Dpoa569_RS10095
uniprot id: A0A5B8I596
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

568768:Dpoa569 RS07155
gene id: 568768:Dpoa569_RS07155
uniprot id: A0A5B8I4V8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

568768:Dpoa569 RS01825
gene id: 568768:Dpoa569_RS01825
uniprot id: A0A5B8I6E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS13365
gene id: 568768:Dpoa569_RS13365
uniprot id: A0A5B8HQ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS03200
gene id: 568768:Dpoa569_RS03200
uniprot id: A0A5B8IL06
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

568768:Dpoa569 RS19080
gene id: 568768:Dpoa569_RS19080
uniprot id: A0A5B8IKJ6
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

568768:Dpoa569 RS03170
gene id: 568768:Dpoa569_RS03170
uniprot id: A0A5B8HH42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

568768:Dpoa569 RS02810
gene id: 568768:Dpoa569_RS02810
uniprot id: A0A5B8I6K2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

568768:Dpoa569 RS07955
gene id: 568768:Dpoa569_RS07955
uniprot id: A0A5B8I7B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

568768:Dpoa569 RS18295
gene id: 568768:Dpoa569_RS18295
uniprot id: A0A5B8IBZ8
names: Similarity
messages: Belongs to the peptidase U62 family.

568768:Dpoa569 RS18470
gene id: 568768:Dpoa569_RS18470
uniprot id: A0A5B8ILZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

568768:Dpoa569 RS14050
gene id: 568768:Dpoa569_RS14050
uniprot id: A0A5B8I7U9
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS17740
gene id: 568768:Dpoa569_RS17740
uniprot id: A0A5B8HR92
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

568768:Dpoa569 RS16245
gene id: 568768:Dpoa569_RS16245
uniprot id: A0A5B8HSF6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

568768:Dpoa569 RS16765
gene id: 568768:Dpoa569_RS16765
uniprot id: A0A5B8HSS3
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS01485
gene id: 568768:Dpoa569_RS01485
uniprot id: A0A5B8HFS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS15155
gene id: 568768:Dpoa569_RS15155
uniprot id: A0A5B8HPR9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

568768:Dpoa569 RS11725
gene id: 568768:Dpoa569_RS11725
uniprot id: A0A5B8I854
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

568768:Dpoa569 RS12720
gene id: 568768:Dpoa569_RS12720
uniprot id: A0A5B8I8K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

568768:Dpoa569 RS00300
gene id: 568768:Dpoa569_RS00300
uniprot id: A0A5B8HDK1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

568768:Dpoa569 RS02760
gene id: 568768:Dpoa569_RS02760
uniprot id: A0A5B8I2C5
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

568768:Dpoa569 RS18515
gene id: 568768:Dpoa569_RS18515
uniprot id: A0A5B8HRQ8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

568768:Dpoa569 RS04730
gene id: 568768:Dpoa569_RS04730
uniprot id: A0A5B8I1R9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS10305
gene id: 568768:Dpoa569_RS10305
uniprot id: A0A5B8I5E4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

568768:Dpoa569 RS00440
gene id: 568768:Dpoa569_RS00440
uniprot id: A0A5B8I0B3
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

568768:Dpoa569 RS11810
gene id: 568768:Dpoa569_RS11810
uniprot id: A0A5B8I9U2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

568768:Dpoa569 RS01890
gene id: 568768:Dpoa569_RS01890
uniprot id: A0A5B8I1I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

568768:Dpoa569 RS02985
gene id: 568768:Dpoa569_RS02985
uniprot id: A0A5B8I0G8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

568768:Dpoa569 RS19245
gene id: 568768:Dpoa569_RS19245
uniprot id: A0A5B8IKQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS15075
gene id: 568768:Dpoa569_RS15075
uniprot id: A0A5B8IF12
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS18575
gene id: 568768:Dpoa569_RS18575
uniprot id: A0A5B8IK05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M20A family. ArgE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS00095
gene id: 568768:Dpoa569_RS00095
uniprot id: A0A5B8IKV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

568768:Dpoa569 RS01545
gene id: 568768:Dpoa569_RS01545
uniprot id: A0A5B8I5T2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

568768:Dpoa569 RS05065
gene id: 568768:Dpoa569_RS05065
uniprot id: A0A5B8I243
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

568768:Dpoa569 RS05605
gene id: 568768:Dpoa569_RS05605
uniprot id: A0A5B8I5X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

568768:Dpoa569 RS19330
gene id: 568768:Dpoa569_RS19330
uniprot id: A0A5B8HUH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

568768:Dpoa569 RS18680
gene id: 568768:Dpoa569_RS18680
uniprot id: A0A5B8IK39
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS15070
gene id: 568768:Dpoa569_RS15070
uniprot id: A0A5B8HRR6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

568768:Dpoa569 RS07100
gene id: 568768:Dpoa569_RS07100
uniprot id: A0A5B8I4Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

568768:Dpoa569 RS04655
gene id: 568768:Dpoa569_RS04655
uniprot id: A0A5B8I7T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

568768:Dpoa569 RS07165
gene id: 568768:Dpoa569_RS07165
uniprot id: A0A5B8HK63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

568768:Dpoa569 RS04140
gene id: 568768:Dpoa569_RS04140
uniprot id: A0A5B8I374
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

568768:Dpoa569 RS10850
gene id: 568768:Dpoa569_RS10850
uniprot id: A0A5B8I7C0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS09830
gene id: 568768:Dpoa569_RS09830
uniprot id: A0A5B8HMN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

568768:Dpoa569 RS15355
gene id: 568768:Dpoa569_RS15355
uniprot id: A0A5B8HRA0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS17960
gene id: 568768:Dpoa569_RS17960
uniprot id: A0A5B8IJF7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

568768:Dpoa569 RS00430
gene id: 568768:Dpoa569_RS00430
uniprot id: A0A5B8HYJ7
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS13835
gene id: 568768:Dpoa569_RS13835
uniprot id: A0A5B8I9K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

568768:Dpoa569 RS14700
gene id: 568768:Dpoa569_RS14700
uniprot id: A0A5B8HQX5
names: Subunit
messages: Homodimer.

568768:Dpoa569 RS12210
gene id: 568768:Dpoa569_RS12210
uniprot id: A0A5B8HV56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

568768:Dpoa569 RS11420
gene id: 568768:Dpoa569_RS11420
uniprot id: A0A5B8HLV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS01220
gene id: 568768:Dpoa569_RS01220
uniprot id: A0A5B8I0U4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

568768:Dpoa569 RS07730
gene id: 568768:Dpoa569_RS07730
uniprot id: A0A5B8HKU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

568768:Dpoa569 RS07415
gene id: 568768:Dpoa569_RS07415
uniprot id: A0A5B8I562
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

568768:Dpoa569 RS07150
gene id: 568768:Dpoa569_RS07150
uniprot id: A0A5B8I512
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

568768:Dpoa569 RS08555
gene id: 568768:Dpoa569_RS08555
uniprot id: A0A5B8ICB3
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS03495
gene id: 568768:Dpoa569_RS03495
uniprot id: A0A5B8I2K4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

568768:Dpoa569 RS14895
gene id: 568768:Dpoa569_RS14895
uniprot id: A0A5B8I9W2
names: Similarity
messages: Belongs to the YkuD family.

568768:Dpoa569 RS12560
gene id: 568768:Dpoa569_RS12560
uniprot id: A0A5B8HPN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

568768:Dpoa569 RS07125
gene id: 568768:Dpoa569_RS07125
uniprot id: A0A5B8I6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

568768:Dpoa569 RS02555
gene id: 568768:Dpoa569_RS02555
uniprot id: A0A5B8HF11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

568768:Dpoa569 RS13435
gene id: 568768:Dpoa569_RS13435
uniprot id: A0A5B8I9D4
names: Similarity
messages: Belongs to the BolA/IbaG family.

568768:Dpoa569 RS13530
gene id: 568768:Dpoa569_RS13530
uniprot id: A0A5B8I959
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

568768:Dpoa569 RS12945
gene id: 568768:Dpoa569_RS12945
uniprot id: A0A5B8IDL3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

568768:Dpoa569 RS09385
gene id: 568768:Dpoa569_RS09385
uniprot id: A0A5B8HMC0
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

568768:Dpoa569 RS12885
gene id: 568768:Dpoa569_RS12885
uniprot id: A0A5B8HQ09
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

568768:Dpoa569 RS16855
gene id: 568768:Dpoa569_RS16855
uniprot id: A0A5B8IBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

568768:Dpoa569 RS12985
gene id: 568768:Dpoa569_RS12985
uniprot id: A0A5B8HN42
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS15215
gene id: 568768:Dpoa569_RS15215
uniprot id: A0A5B8HRU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

568768:Dpoa569 RS18615
gene id: 568768:Dpoa569_RS18615
uniprot id: A0A5B8HRS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

568768:Dpoa569 RS15965
gene id: 568768:Dpoa569_RS15965
uniprot id: A0A5B8IHV0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

568768:Dpoa569 RS09350
gene id: 568768:Dpoa569_RS09350
uniprot id: A0A5B8I6F0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

568768:Dpoa569 RS08165
gene id: 568768:Dpoa569_RS08165
uniprot id: A0A5B8HL26
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

568768:Dpoa569 RS13470
gene id: 568768:Dpoa569_RS13470
uniprot id: A0A5B8IFX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

568768:Dpoa569 RS15220
gene id: 568768:Dpoa569_RS15220
uniprot id: A0A5B8IF42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

568768:Dpoa569 RS09720
gene id: 568768:Dpoa569_RS09720
uniprot id: A0A5B8IBE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

568768:Dpoa569 RS00930
gene id: 568768:Dpoa569_RS00930
uniprot id: A0A5B8HE45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

568768:Dpoa569 RS11370
gene id: 568768:Dpoa569_RS11370
uniprot id: A0A5B8ICK2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

568768:Dpoa569 RS17170
gene id: 568768:Dpoa569_RS17170
uniprot id: A0A5B8IDA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

568768:Dpoa569 RS10645
gene id: 568768:Dpoa569_RS10645
uniprot id: A0A5B8IC26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS05035
gene id: 568768:Dpoa569_RS05035
uniprot id: A0A5B8HIL4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

568768:Dpoa569 RS10255
gene id: 568768:Dpoa569_RS10255
uniprot id: A0A5B8I5D2
names: Similarity
messages: Belongs to the RNase T2 family.

568768:Dpoa569 RS00665
gene id: 568768:Dpoa569_RS00665
uniprot id: A0A5B8I5A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

568768:Dpoa569 RS12175
gene id: 568768:Dpoa569_RS12175
uniprot id: A0A5B8I6L1
names: Function
names: Similarity
messages: Belongs to the EfeM/EfeO family.
messages: Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component.

568768:Dpoa569 RS15235
gene id: 568768:Dpoa569_RS15235
uniprot id: A0A5B8IH78
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

568768:Dpoa569 RS02075
gene id: 568768:Dpoa569_RS02075
uniprot id: A0A5B8I1L0
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

568768:Dpoa569 RS02275
gene id: 568768:Dpoa569_RS02275
uniprot id: A0A5B8I1S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

568768:Dpoa569 RS12075
gene id: 568768:Dpoa569_RS12075
uniprot id: A0A5B8I6I1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS17455
gene id: 568768:Dpoa569_RS17455
uniprot id: A0A5B8HT74
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

568768:Dpoa569 RS07105
gene id: 568768:Dpoa569_RS07105
uniprot id: A0A5B8I4U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

568768:Dpoa569 RS04460
gene id: 568768:Dpoa569_RS04460
uniprot id: A0A5B8I3D2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

568768:Dpoa569 RS02395
gene id: 568768:Dpoa569_RS02395
uniprot id: A0A5B8I1Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

568768:Dpoa569 RS01650
gene id: 568768:Dpoa569_RS01650
uniprot id: A0A5B8I5V1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

568768:Dpoa569 RS01860
gene id: 568768:Dpoa569_RS01860
uniprot id: A0A5B8HG20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

568768:Dpoa569 RS18550
gene id: 568768:Dpoa569_RS18550
uniprot id: A0A5B8IAT8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

568768:Dpoa569 RS05985
gene id: 568768:Dpoa569_RS05985
uniprot id: A0A5B8I8X4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

568768:Dpoa569 RS04610
gene id: 568768:Dpoa569_RS04610
uniprot id: A0A5B8HIS7
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS07840
gene id: 568768:Dpoa569_RS07840
uniprot id: A0A5B8I762
names: Similarity
messages: Belongs to the pyruvate kinase family.

568768:Dpoa569 RS15700
gene id: 568768:Dpoa569_RS15700
uniprot id: A0A5B8I8Z3
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

568768:Dpoa569 RS16165
gene id: 568768:Dpoa569_RS16165
uniprot id: A0A5B8HQC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

568768:Dpoa569 RS04360
gene id: 568768:Dpoa569_RS04360
uniprot id: A0A5B8HIM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

568768:Dpoa569 RS16755
gene id: 568768:Dpoa569_RS16755
uniprot id: A0A5B8HQP4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

568768:Dpoa569 RS00595
gene id: 568768:Dpoa569_RS00595
uniprot id: A0A5B8I0E8
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

568768:Dpoa569 RS06060
gene id: 568768:Dpoa569_RS06060
uniprot id: A0A5B8HJU1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS09450
gene id: 568768:Dpoa569_RS09450
uniprot id: A0A5B8I6B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS18745
gene id: 568768:Dpoa569_RS18745
uniprot id: A0A5B8HT28
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

568768:Dpoa569 RS08635
gene id: 568768:Dpoa569_RS08635
uniprot id: A0A5B8HLK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS15035
gene id: 568768:Dpoa569_RS15035
uniprot id: A0A5B8HR41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

568768:Dpoa569 RS10455
gene id: 568768:Dpoa569_RS10455
uniprot id: A0A5B8I749
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

568768:Dpoa569 RS10070
gene id: 568768:Dpoa569_RS10070
uniprot id: A0A5B8IBN1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS00170
gene id: 568768:Dpoa569_RS00170
uniprot id: A0A5B8I048
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

568768:Dpoa569 RS07720
gene id: 568768:Dpoa569_RS07720
uniprot id: A0A5B8IA38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

568768:Dpoa569 RS10360
gene id: 568768:Dpoa569_RS10360
uniprot id: A0A5B8I778
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS07300
gene id: 568768:Dpoa569_RS07300
uniprot id: A0A5B8IBC8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS18005
gene id: 568768:Dpoa569_RS18005
uniprot id: A0A5B8HTK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

568768:Dpoa569 RS02635
gene id: 568768:Dpoa569_RS02635
uniprot id: A0A5B8I205
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

568768:Dpoa569 RS02115
gene id: 568768:Dpoa569_RS02115
uniprot id: A0A5B8HZU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

568768:Dpoa569 RS09665
gene id: 568768:Dpoa569_RS09665
uniprot id: A0A5B8IBD2
names: Similarity
messages: Belongs to the ribulokinase family.

568768:Dpoa569 RS03130
gene id: 568768:Dpoa569_RS03130
uniprot id: A0A5B8HHL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

568768:Dpoa569 RS13850
gene id: 568768:Dpoa569_RS13850
uniprot id: A0A5B8HQU8
names: Similarity
messages: Belongs to the skp family.

568768:Dpoa569 RS00265
gene id: 568768:Dpoa569_RS00265
uniprot id: A0A5B8HYD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

568768:Dpoa569 RS00980
gene id: 568768:Dpoa569_RS00980
uniprot id: A0A5B8I0P1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

568768:Dpoa569 RS03035
gene id: 568768:Dpoa569_RS03035
uniprot id: A0A5B8I2E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

568768:Dpoa569 RS13840
gene id: 568768:Dpoa569_RS13840
uniprot id: A0A5B8I921
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

568768:Dpoa569 RS09110
gene id: 568768:Dpoa569_RS09110
uniprot id: A0A5B8ICP8
names: Subcellular Location Annotation
messages: Cytoplasm

568768:Dpoa569 RS11380
gene id: 568768:Dpoa569_RS11380
uniprot id: A0A5B8HNU7
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

568768:Dpoa569 RS04195
gene id: 568768:Dpoa569_RS04195
uniprot id: A0A5B8I4Y4
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

568768:Dpoa569 RS10855
gene id: 568768:Dpoa569_RS10855
uniprot id: A0A5B8I5R4
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

568768:Dpoa569 RS10675
gene id: 568768:Dpoa569_RS10675
uniprot id: A0A5B8I5N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

568768:Dpoa569 RS13140
gene id: 568768:Dpoa569_RS13140
uniprot id: A0A5B8HQ72
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS11090
gene id: 568768:Dpoa569_RS11090
uniprot id: A0A5B8HNP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS01465
gene id: 568768:Dpoa569_RS01465
uniprot id: A0A5B8HZB3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

568768:Dpoa569 RS14955
gene id: 568768:Dpoa569_RS14955
uniprot id: A0A5B8IA87
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

568768:Dpoa569 RS14865
gene id: 568768:Dpoa569_RS14865
uniprot id: A0A5B8HPK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS16250
gene id: 568768:Dpoa569_RS16250
uniprot id: A0A5B8IHX7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

568768:Dpoa569 RS13190
gene id: 568768:Dpoa569_RS13190
uniprot id: A0A5B8HNA8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

568768:Dpoa569 RS13185
gene id: 568768:Dpoa569_RS13185
uniprot id: A0A5B8I8N1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

568768:Dpoa569 RS02495
gene id: 568768:Dpoa569_RS02495
uniprot id: A0A5B8IL25
names: Similarity
messages: Belongs to the OsmC/Ohr family.

568768:Dpoa569 RS11890
gene id: 568768:Dpoa569_RS11890
uniprot id: A0A5B8IEL5
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS15280
gene id: 568768:Dpoa569_RS15280
uniprot id: A0A5B8HPT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

568768:Dpoa569 RS03680
gene id: 568768:Dpoa569_RS03680
uniprot id: A0A5B8HHG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

568768:Dpoa569 RS18770
gene id: 568768:Dpoa569_RS18770
uniprot id: A0A5B8ICR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

568768:Dpoa569 RS04130
gene id: 568768:Dpoa569_RS04130
uniprot id: A0A5B8I361
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS01070
gene id: 568768:Dpoa569_RS01070
uniprot id: A0A5B8I5J9
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

568768:Dpoa569 RS05320
gene id: 568768:Dpoa569_RS05320
uniprot id: A0A5B8I8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS00080
gene id: 568768:Dpoa569_RS00080
uniprot id: A0A5B8ICH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

568768:Dpoa569 RS07035
gene id: 568768:Dpoa569_RS07035
uniprot id: A0A5B8I4Y7
names: Similarity
messages: Belongs to the MotB family.

568768:Dpoa569 RS18095
gene id: 568768:Dpoa569_RS18095
uniprot id: A0A5B8IAL2
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

568768:Dpoa569 RS03695
gene id: 568768:Dpoa569_RS03695
uniprot id: A0A5B8HI29
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS17840
gene id: 568768:Dpoa569_RS17840
uniprot id: A0A5B8IBC1
names: Similarity
messages: Belongs to the UPF0306 family.

568768:Dpoa569 RS08685
gene id: 568768:Dpoa569_RS08685
uniprot id: A0A5B8I5W7
names: Function
names: Similarity
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

568768:Dpoa569 RS08130
gene id: 568768:Dpoa569_RS08130
uniprot id: A0A5B8HL57
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

568768:Dpoa569 RS19300
gene id: 568768:Dpoa569_RS19300
uniprot id: A0A5B8ICP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS14505
gene id: 568768:Dpoa569_RS14505
uniprot id: A0A5B8I9D8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS13635
gene id: 568768:Dpoa569_RS13635
uniprot id: A0A5B8IG31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

568768:Dpoa569 RS09925
gene id: 568768:Dpoa569_RS09925
uniprot id: A0A5B8HMR4
names: Similarity
messages: Belongs to the UPF0225 family.

568768:Dpoa569 RS01905
gene id: 568768:Dpoa569_RS01905
uniprot id: A0A5B8I1D1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

568768:Dpoa569 RS11120
gene id: 568768:Dpoa569_RS11120
uniprot id: A0A5B8I5X6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

568768:Dpoa569 RS01170
gene id: 568768:Dpoa569_RS01170
uniprot id: A0A5B8I0T2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

568768:Dpoa569 RS11680
gene id: 568768:Dpoa569_RS11680
uniprot id: A0A5B8HM43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

568768:Dpoa569 RS16350
gene id: 568768:Dpoa569_RS16350
uniprot id: A0A5B8IB37
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS03460
gene id: 568768:Dpoa569_RS03460
uniprot id: A0A5B8I6Z7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

568768:Dpoa569 RS13585
gene id: 568768:Dpoa569_RS13585
uniprot id: A0A5B8I7H3
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

568768:Dpoa569 RS11220
gene id: 568768:Dpoa569_RS11220
uniprot id: A0A5B8I7J3
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

568768:Dpoa569 RS08510
gene id: 568768:Dpoa569_RS08510
uniprot id: A0A5B8I5V2
names: Similarity
messages: Belongs to the peptidase S41A family.

568768:Dpoa569 RS03315
gene id: 568768:Dpoa569_RS03315
uniprot id: A0A5B8I0Q4
names: Similarity
messages: Belongs to the LOG family.

568768:Dpoa569 RS15900
gene id: 568768:Dpoa569_RS15900
uniprot id: A0A5B8ICG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane
messages: Type II secretion system is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. Forms homomultimers.

568768:Dpoa569 RS01800
gene id: 568768:Dpoa569_RS01800
uniprot id: A0A5B8HEM4
names: Subcellular Location Annotation
messages: Cell inner membrane

568768:Dpoa569 RS17760
gene id: 568768:Dpoa569_RS17760
uniprot id: A0A5B8HSH8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

568768:Dpoa569 RS13520
gene id: 568768:Dpoa569_RS13520
uniprot id: A0A5B8HQ80
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

568768:Dpoa569 RS16985
gene id: 568768:Dpoa569_RS16985
uniprot id: A0A5B8IIL9
names: Similarity
messages: Belongs to the thioesterase family.

568768:Dpoa569 RS13110
gene id: 568768:Dpoa569_RS13110
uniprot id: A0A5B8IFN7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

568768:Dpoa569 RS16670
gene id: 568768:Dpoa569_RS16670
uniprot id: A0A5B8IIB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

568768:Dpoa569 RS16105
gene id: 568768:Dpoa569_RS16105
uniprot id: A0A5B8HSC4
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS11980
gene id: 568768:Dpoa569_RS11980
uniprot id: A0A5B8I9X7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Binds 1 sodium ion per monomer.
messages: Binds 2 magnesium ions per monomer.
messages: Homotetramer.

568768:Dpoa569 RS09440
gene id: 568768:Dpoa569_RS09440
uniprot id: A0A5B8HMD6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

568768:Dpoa569 RS15915
gene id: 568768:Dpoa569_RS15915
uniprot id: A0A5B8IHT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

568768:Dpoa569 RS10860
gene id: 568768:Dpoa569_RS10860
uniprot id: A0A5B8I7H8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

568768:Dpoa569 RS12860
gene id: 568768:Dpoa569_RS12860
uniprot id: A0A5B8I8Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS15670
gene id: 568768:Dpoa569_RS15670
uniprot id: A0A5B8ICA6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

568768:Dpoa569 RS09910
gene id: 568768:Dpoa569_RS09910
uniprot id: A0A5B8HMR6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

568768:Dpoa569 RS04595
gene id: 568768:Dpoa569_RS04595
uniprot id: A0A5B8HI75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

568768:Dpoa569 RS02240
gene id: 568768:Dpoa569_RS02240
uniprot id: A0A5B8I680
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

568768:Dpoa569 RS09560
gene id: 568768:Dpoa569_RS09560
uniprot id: A0A5B8HV18
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

568768:Dpoa569 RS18555
gene id: 568768:Dpoa569_RS18555
uniprot id: A0A5B8ICL6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

568768:Dpoa569 RS03780
gene id: 568768:Dpoa569_RS03780
uniprot id: A0A5B8HHJ9
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

568768:Dpoa569 RS05560
gene id: 568768:Dpoa569_RS05560
uniprot id: A0A5B8I8P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS12370
gene id: 568768:Dpoa569_RS12370
uniprot id: A0A5B8IA58
names: Similarity
messages: Belongs to the UPF0053 family.

568768:Dpoa569 RS00625
gene id: 568768:Dpoa569_RS00625
uniprot id: A0A5B8I5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell inner membrane

568768:Dpoa569 RS12570
gene id: 568768:Dpoa569_RS12570
uniprot id: A0A5B8I8F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

568768:Dpoa569 RS18760
gene id: 568768:Dpoa569_RS18760
uniprot id: A0A5B8IC98
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

568768:Dpoa569 RS13040
gene id: 568768:Dpoa569_RS13040
uniprot id: A0A5B8HQ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

568768:Dpoa569 RS11630
gene id: 568768:Dpoa569_RS11630
uniprot id: A0A5B8ICR4
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS12820
gene id: 568768:Dpoa569_RS12820
uniprot id: A0A5B8IBX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

568768:Dpoa569 RS10395
gene id: 568768:Dpoa569_RS10395
uniprot id: A0A5B8HN51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

568768:Dpoa569 RS05550
gene id: 568768:Dpoa569_RS05550
uniprot id: A0A5B8I5V9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

568768:Dpoa569 RS04845
gene id: 568768:Dpoa569_RS04845
uniprot id: A0A5B8I1U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS00035
gene id: 568768:Dpoa569_RS00035
uniprot id: A0A5B8HS88
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

568768:Dpoa569 RS07620
gene id: 568768:Dpoa569_RS07620
uniprot id: A0A5B8HKS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

568768:Dpoa569 RS08745
gene id: 568768:Dpoa569_RS08745
uniprot id: A0A5B8IBR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

568768:Dpoa569 RS02330
gene id: 568768:Dpoa569_RS02330
uniprot id: A0A5B8I6R1
names: Cofactor
messages: Can also use Mn(2+) ion.

568768:Dpoa569 RS16510
gene id: 568768:Dpoa569_RS16510
uniprot id: A0A5B8I9D9
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

568768:Dpoa569 RS01110
gene id: 568768:Dpoa569_RS01110
uniprot id: A0A5B8HZ29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

568768:Dpoa569 RS14605
gene id: 568768:Dpoa569_RS14605
uniprot id: A0A5B8IGQ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

568768:Dpoa569 RS11180
gene id: 568768:Dpoa569_RS11180
uniprot id: A0A5B8I7S5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS07970
gene id: 568768:Dpoa569_RS07970
uniprot id: A0A5B8I5J2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

568768:Dpoa569 RS11800
gene id: 568768:Dpoa569_RS11800
uniprot id: A0A5B8HP78
names: Similarity
messages: Belongs to the RutC family.

568768:Dpoa569 RS09820
gene id: 568768:Dpoa569_RS09820
uniprot id: A0A5B8IBH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

568768:Dpoa569 RS00630
gene id: 568768:Dpoa569_RS00630
uniprot id: A0A5B8I0L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcrB family.
messages: Cell membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered.

568768:Dpoa569 RS12910
gene id: 568768:Dpoa569_RS12910
uniprot id: A0A5B8I8R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

568768:Dpoa569 RS04075
gene id: 568768:Dpoa569_RS04075
uniprot id: A0A5B8I349
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

568768:Dpoa569 RS08145
gene id: 568768:Dpoa569_RS08145
uniprot id: A0A5B8I433
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

568768:Dpoa569 RS12380
gene id: 568768:Dpoa569_RS12380
uniprot id: A0A5B8IEZ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS12620
gene id: 568768:Dpoa569_RS12620
uniprot id: A0A5B8I8G9
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

568768:Dpoa569 RS02720
gene id: 568768:Dpoa569_RS02720
uniprot id: A0A5B8I270
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

568768:Dpoa569 RS04500
gene id: 568768:Dpoa569_RS04500
uniprot id: A0A5B8HIQ3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

568768:Dpoa569 RS04365
gene id: 568768:Dpoa569_RS04365
uniprot id: A0A5B8I802
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

568768:Dpoa569 RS02775
gene id: 568768:Dpoa569_RS02775
uniprot id: A0A5B8I283
names: Similarity
messages: Belongs to the UPF0246 family.

568768:Dpoa569 RS15620
gene id: 568768:Dpoa569_RS15620
uniprot id: A0A5B8IC93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

568768:Dpoa569 RS04415
gene id: 568768:Dpoa569_RS04415
uniprot id: A0A5B8I369
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

568768:Dpoa569 RS10205
gene id: 568768:Dpoa569_RS10205
uniprot id: A0A5B8I6X9
names: Similarity
messages: Belongs to the UPF0502 family.

568768:Dpoa569 RS15210
gene id: 568768:Dpoa569_RS15210
uniprot id: A0A5B8HPS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

568768:Dpoa569 RS10865
gene id: 568768:Dpoa569_RS10865
uniprot id: A0A5B8I7A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS04640
gene id: 568768:Dpoa569_RS04640
uniprot id: A0A5B8HSF3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

568768:Dpoa569 RS18785
gene id: 568768:Dpoa569_RS18785
uniprot id: A0A5B8HU60
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.

568768:Dpoa569 RS09065
gene id: 568768:Dpoa569_RS09065
uniprot id: A0A5B8I4K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS02100
gene id: 568768:Dpoa569_RS02100
uniprot id: A0A5B8HEQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

568768:Dpoa569 RS01415
gene id: 568768:Dpoa569_RS01415
uniprot id: A0A5B8HFR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzyE family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

568768:Dpoa569 RS11080
gene id: 568768:Dpoa569_RS11080
uniprot id: A0A5B8I7F1
names: Similarity
messages: Belongs to the Dps family.

568768:Dpoa569 RS00615
gene id: 568768:Dpoa569_RS00615
uniprot id: A0A5B8I0F6
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

568768:Dpoa569 RS02250
gene id: 568768:Dpoa569_RS02250
uniprot id: A0A5B8HEU3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

568768:Dpoa569 RS04025
gene id: 568768:Dpoa569_RS04025
uniprot id: A0A5B8I1A5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS18660
gene id: 568768:Dpoa569_RS18660
uniprot id: A0A5B8ICP5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

568768:Dpoa569 RS07880
gene id: 568768:Dpoa569_RS07880
uniprot id: A0A5B8I5B0
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

568768:Dpoa569 RS01395
gene id: 568768:Dpoa569_RS01395
uniprot id: A0A5B8HZ96
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS18215
gene id: 568768:Dpoa569_RS18215
uniprot id: A0A5B8HTR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

568768:Dpoa569 RS01900
gene id: 568768:Dpoa569_RS01900
uniprot id: A0A5B8I1C8
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.

568768:Dpoa569 RS11225
gene id: 568768:Dpoa569_RS11225
uniprot id: A0A5B8I5Z7
names: Similarity
messages: Belongs to the MoaD family.

568768:Dpoa569 RS11425
gene id: 568768:Dpoa569_RS11425
uniprot id: A0A5B8HNY4
names: Similarity
messages: Belongs to the fabD family.

568768:Dpoa569 RS02260
gene id: 568768:Dpoa569_RS02260
uniprot id: A0A5B8I1V3
names: Similarity
messages: Belongs to the Smg family.

568768:Dpoa569 RS05920
gene id: 568768:Dpoa569_RS05920
uniprot id: A0A5B8HJA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Periplasm

568768:Dpoa569 RS10110
gene id: 568768:Dpoa569_RS10110
uniprot id: A0A5B8HKQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS02610
gene id: 568768:Dpoa569_RS02610
uniprot id: A0A5B8I6X3
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

568768:Dpoa569 RS05475
gene id: 568768:Dpoa569_RS05475
uniprot id: A0A5B8I8I0
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS12315
gene id: 568768:Dpoa569_RS12315
uniprot id: A0A5B8ID78
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

568768:Dpoa569 RS13510
gene id: 568768:Dpoa569_RS13510
uniprot id: A0A5B8IE25
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

568768:Dpoa569 RS03520
gene id: 568768:Dpoa569_RS03520
uniprot id: A0A5B8I2W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS07890
gene id: 568768:Dpoa569_RS07890
uniprot id: A0A5B8HKV0
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

568768:Dpoa569 RS09995
gene id: 568768:Dpoa569_RS09995
uniprot id: A0A5B8I6P7
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

568768:Dpoa569 RS19295
gene id: 568768:Dpoa569_RS19295
uniprot id: A0A5B8IKS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS08365
gene id: 568768:Dpoa569_RS08365
uniprot id: A0A5B8I489
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

568768:Dpoa569 RS13505
gene id: 568768:Dpoa569_RS13505
uniprot id: A0A5B8HQH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

568768:Dpoa569 RS11835
gene id: 568768:Dpoa569_RS11835
uniprot id: A0A5B8I7W7
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

568768:Dpoa569 RS09880
gene id: 568768:Dpoa569_RS09880
uniprot id: A0A5B8HMP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

568768:Dpoa569 RS13535
gene id: 568768:Dpoa569_RS13535
uniprot id: A0A5B8I7G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

568768:Dpoa569 RS12195
gene id: 568768:Dpoa569_RS12195
uniprot id: A0A5B8HPM3
names: Similarity
messages: Belongs to the Dps family.

568768:Dpoa569 RS12670
gene id: 568768:Dpoa569_RS12670
uniprot id: A0A5B8I8I2
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

568768:Dpoa569 RS10290
gene id: 568768:Dpoa569_RS10290
uniprot id: A0A5B8HN21
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. MukB subfamily.
messages: Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.
messages: Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
messages: The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
messages: nucleoid

568768:Dpoa569 RS18460
gene id: 568768:Dpoa569_RS18460
uniprot id: A0A5B8HTX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

568768:Dpoa569 RS11570
gene id: 568768:Dpoa569_RS11570
uniprot id: A0A5B8HM00
names: Similarity
messages: Belongs to the glycosyl hydrolase.

568768:Dpoa569 RS15585
gene id: 568768:Dpoa569_RS15585
uniprot id: A0A5B8IA99
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

568768:Dpoa569 RS16865
gene id: 568768:Dpoa569_RS16865
uniprot id: A0A5B8HQS4
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

568768:Dpoa569 RS17185
gene id: 568768:Dpoa569_RS17185
uniprot id: A0A5B8IIR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

568768:Dpoa569 RS05860
gene id: 568768:Dpoa569_RS05860
uniprot id: A0A5B8HJ89
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

568768:Dpoa569 RS15760
gene id: 568768:Dpoa569_RS15760
uniprot id: A0A5B8IA45
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

568768:Dpoa569 RS19385
gene id: 568768:Dpoa569_RS19385
uniprot id: A0A5B8IKR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

568768:Dpoa569 RS02705
gene id: 568768:Dpoa569_RS02705
uniprot id: A0A5B8I2B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

568768:Dpoa569 RS09675
gene id: 568768:Dpoa569_RS09675
uniprot id: A0A5B8HMJ2
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

568768:Dpoa569 RS18625
gene id: 568768:Dpoa569_RS18625
uniprot id: A0A5B8IK22
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

568768:Dpoa569 RS00780
gene id: 568768:Dpoa569_RS00780
uniprot id: A0A5B8HDW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS13590
gene id: 568768:Dpoa569_RS13590
uniprot id: A0A5B8HV72
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS00270
gene id: 568768:Dpoa569_RS00270
uniprot id: A0A5B8I081
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

568768:Dpoa569 RS01740
gene id: 568768:Dpoa569_RS01740
uniprot id: A0A5B8I183
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

568768:Dpoa569 RS16610
gene id: 568768:Dpoa569_RS16610
uniprot id: A0A5B8HRX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

568768:Dpoa569 RS02845
gene id: 568768:Dpoa569_RS02845
uniprot id: A0A5B8I259
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

568768:Dpoa569 RS10670
gene id: 568768:Dpoa569_RS10670
uniprot id: A0A5B8I787
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS03110
gene id: 568768:Dpoa569_RS03110
uniprot id: A0A5B8HFM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

568768:Dpoa569 RS15875
gene id: 568768:Dpoa569_RS15875
uniprot id: A0A5B8IAS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS00710
gene id: 568768:Dpoa569_RS00710
uniprot id: A0A5B8HF48
names: Similarity
messages: Belongs to the ABC transporter superfamily.

568768:Dpoa569 RS15750
gene id: 568768:Dpoa569_RS15750
uniprot id: A0A5B8I903
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

568768:Dpoa569 RS04510
gene id: 568768:Dpoa569_RS04510
uniprot id: A0A5B8I3E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

568768:Dpoa569 RS00240
gene id: 568768:Dpoa569_RS00240
uniprot id: A0A5B8I526
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

568768:Dpoa569 RS02065
gene id: 568768:Dpoa569_RS02065
uniprot id: A0A5B8HE36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

568768:Dpoa569 RS07855
gene id: 568768:Dpoa569_RS07855
uniprot id: A0A5B8I5G6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

568768:Dpoa569 RS17835
gene id: 568768:Dpoa569_RS17835
uniprot id: A0A5B8IBZ6
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

568768:Dpoa569 RS02895
gene id: 568768:Dpoa569_RS02895
uniprot id: A0A5B8I269
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Cell inner membrane
messages: Involved in succinate export with YjjP. Both proteins are required for export.
messages: Membrane
messages: The transporter is composed of YjjB and YjjP.

568768:Dpoa569 RS08620
gene id: 568768:Dpoa569_RS08620
uniprot id: A0A5B8I5Z3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

568768:Dpoa569 RS08265
gene id: 568768:Dpoa569_RS08265
uniprot id: A0A5B8I5Q7
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS05845
gene id: 568768:Dpoa569_RS05845
uniprot id: A0A5B8I4A1
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

568768:Dpoa569 RS10040
gene id: 568768:Dpoa569_RS10040
uniprot id: A0A5B8I6Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance.
messages: Membrane

568768:Dpoa569 RS08705
gene id: 568768:Dpoa569_RS08705
uniprot id: A0A5B8IAT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

568768:Dpoa569 RS01730
gene id: 568768:Dpoa569_RS01730
uniprot id: A0A5B8HZL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

568768:Dpoa569 RS10560
gene id: 568768:Dpoa569_RS10560
uniprot id: A0A5B8I771
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

568768:Dpoa569 RS14625
gene id: 568768:Dpoa569_RS14625
uniprot id: A0A5B8I9G3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

568768:Dpoa569 RS09255
gene id: 568768:Dpoa569_RS09255
uniprot id: A0A5B8HM86
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

568768:Dpoa569 RS02085
gene id: 568768:Dpoa569_RS02085
uniprot id: A0A5B8HG78
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

568768:Dpoa569 RS14875
gene id: 568768:Dpoa569_RS14875
uniprot id: A0A5B8IEW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

568768:Dpoa569 RS12875
gene id: 568768:Dpoa569_RS12875
uniprot id: A0A5B8I8F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

568768:Dpoa569 RS10895
gene id: 568768:Dpoa569_RS10895
uniprot id: A0A5B8HNH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS02200
gene id: 568768:Dpoa569_RS02200
uniprot id: A0A5B8HET1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

568768:Dpoa569 RS10835
gene id: 568768:Dpoa569_RS10835
uniprot id: A0A5B8ILL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

568768:Dpoa569 RS18720
gene id: 568768:Dpoa569_RS18720
uniprot id: A0A5B8IC57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

568768:Dpoa569 RS18135
gene id: 568768:Dpoa569_RS18135
uniprot id: A0A5B8IJQ3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

568768:Dpoa569 RS13325
gene id: 568768:Dpoa569_RS13325
uniprot id: A0A5B8I7B1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

568768:Dpoa569 RS16440
gene id: 568768:Dpoa569_RS16440
uniprot id: A0A5B8IAR2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS13605
gene id: 568768:Dpoa569_RS13605
uniprot id: A0A5B8I8X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

568768:Dpoa569 RS02400
gene id: 568768:Dpoa569_RS02400
uniprot id: A0A5B8I022
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

568768:Dpoa569 RS18090
gene id: 568768:Dpoa569_RS18090
uniprot id: A0A5B8IBU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

568768:Dpoa569 RS05710
gene id: 568768:Dpoa569_RS05710
uniprot id: A0A5B8I8N4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

568768:Dpoa569 RS08190
gene id: 568768:Dpoa569_RS08190
uniprot id: A0A5B8IC17
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS18570
gene id: 568768:Dpoa569_RS18570
uniprot id: A0A5B8HTZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

568768:Dpoa569 RS09945
gene id: 568768:Dpoa569_RS09945
uniprot id: A0A5B8I564
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

568768:Dpoa569 RS02160
gene id: 568768:Dpoa569_RS02160
uniprot id: A0A5B8I1S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

568768:Dpoa569 RS01955
gene id: 568768:Dpoa569_RS01955
uniprot id: A0A5B8I1J9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

568768:Dpoa569 RS18935
gene id: 568768:Dpoa569_RS18935
uniprot id: A0A5B8IC31
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

568768:Dpoa569 RS04535
gene id: 568768:Dpoa569_RS04535
uniprot id: A0A5B8HI60
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS18380
gene id: 568768:Dpoa569_RS18380
uniprot id: A0A5B8IJS5
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

568768:Dpoa569 RS16720
gene id: 568768:Dpoa569_RS16720
uniprot id: A0A5B8ID00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

568768:Dpoa569 RS18200
gene id: 568768:Dpoa569_RS18200
uniprot id: A0A5B8ICC2
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS12485
gene id: 568768:Dpoa569_RS12485
uniprot id: A0A5B8I8E3
names: Similarity
messages: Belongs to the aldose epimerase family.

568768:Dpoa569 RS12295
gene id: 568768:Dpoa569_RS12295
uniprot id: A0A5B8I8I7
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS09710
gene id: 568768:Dpoa569_RS09710
uniprot id: A0A5B8HK71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

568768:Dpoa569 RS05785
gene id: 568768:Dpoa569_RS05785
uniprot id: A0A5B8I490
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

568768:Dpoa569 RS18465
gene id: 568768:Dpoa569_RS18465
uniprot id: A0A5B8IJT3
names: Similarity
messages: Belongs to the IMPACT family.

568768:Dpoa569 RS12775
gene id: 568768:Dpoa569_RS12775
uniprot id: A0A5B8I6Z6
names: Similarity
messages: Belongs to the asparagine synthetase family.

568768:Dpoa569 RS00320
gene id: 568768:Dpoa569_RS00320
uniprot id: A0A5B8I091
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

568768:Dpoa569 RS10490
gene id: 568768:Dpoa569_RS10490
uniprot id: A0A5B8I930
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS03865
gene id: 568768:Dpoa569_RS03865
uniprot id: A0A5B8HUQ7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

568768:Dpoa569 RS00915
gene id: 568768:Dpoa569_RS00915
uniprot id: A0A5B8HYZ2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

568768:Dpoa569 RS00220
gene id: 568768:Dpoa569_RS00220
uniprot id: A0A5B8I069
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

568768:Dpoa569 RS18160
gene id: 568768:Dpoa569_RS18160
uniprot id: A0A5B8HRI2
names: Similarity
messages: Belongs to the peptidase S1C family.

568768:Dpoa569 RS15515
gene id: 568768:Dpoa569_RS15515
uniprot id: A0A5B8IFC3
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS07785
gene id: 568768:Dpoa569_RS07785
uniprot id: A0A5B8HKW3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

568768:Dpoa569 RS04325
gene id: 568768:Dpoa569_RS04325
uniprot id: A0A5B8I1H5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

568768:Dpoa569 RS05800
gene id: 568768:Dpoa569_RS05800
uniprot id: A0A5B8I447
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

568768:Dpoa569 RS04630
gene id: 568768:Dpoa569_RS04630
uniprot id: A0A5B8I3I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

568768:Dpoa569 RS18100
gene id: 568768:Dpoa569_RS18100
uniprot id: A0A5B8IC95
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

568768:Dpoa569 RS17225
gene id: 568768:Dpoa569_RS17225
uniprot id: A0A5B8IDB5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

568768:Dpoa569 RS09970
gene id: 568768:Dpoa569_RS09970
uniprot id: A0A5B8IBK4
names: Similarity
messages: Belongs to the asparaginase 1 family.

568768:Dpoa569 RS16205
gene id: 568768:Dpoa569_RS16205
uniprot id: A0A5B8IAL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS08260
gene id: 568768:Dpoa569_RS08260
uniprot id: A0A5B8IF55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

568768:Dpoa569 RS01970
gene id: 568768:Dpoa569_RS01970
uniprot id: A0A5B8I1I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
messages: Cell inner membrane
messages: Interacts with KefB.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.

568768:Dpoa569 RS02090
gene id: 568768:Dpoa569_RS02090
uniprot id: A0A5B8I636
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

568768:Dpoa569 RS13305
gene id: 568768:Dpoa569_RS13305
uniprot id: A0A5B8IAQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

568768:Dpoa569 RS12880
gene id: 568768:Dpoa569_RS12880
uniprot id: A0A5B8HN07
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

568768:Dpoa569 RS10680
gene id: 568768:Dpoa569_RS10680
uniprot id: A0A5B8I7E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

568768:Dpoa569 RS01405
gene id: 568768:Dpoa569_RS01405
uniprot id: A0A5B8I0Z6
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS03030
gene id: 568768:Dpoa569_RS03030
uniprot id: A0A5B8I774
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS06995
gene id: 568768:Dpoa569_RS06995
uniprot id: A0A5B8HIA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

568768:Dpoa569 RS18425
gene id: 568768:Dpoa569_RS18425
uniprot id: A0A5B8IBR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS16400
gene id: 568768:Dpoa569_RS16400
uniprot id: A0A5B8IB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

568768:Dpoa569 RS10375
gene id: 568768:Dpoa569_RS10375
uniprot id: A0A5B8HL11
names: Similarity
messages: Belongs to the CitG/MdcB family.

568768:Dpoa569 RS03550
gene id: 568768:Dpoa569_RS03550
uniprot id: A0A5B8I2L9
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

568768:Dpoa569 RS12825
gene id: 568768:Dpoa569_RS12825
uniprot id: A0A5B8I8E6
names: Similarity
messages: Belongs to the PhoH family.

568768:Dpoa569 RS02890
gene id: 568768:Dpoa569_RS02890
uniprot id: A0A5B8I276
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

568768:Dpoa569 RS04530
gene id: 568768:Dpoa569_RS04530
uniprot id: A0A5B8HGH4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

568768:Dpoa569 RS12520
gene id: 568768:Dpoa569_RS12520
uniprot id: A0A5B8HU84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

568768:Dpoa569 RS07315
gene id: 568768:Dpoa569_RS07315
uniprot id: A0A5B8I3J0
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

568768:Dpoa569 RS02930
gene id: 568768:Dpoa569_RS02930
uniprot id: A0A5B8I2B7
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

568768:Dpoa569 RS17155
gene id: 568768:Dpoa569_RS17155
uniprot id: A0A5B8IIR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

568768:Dpoa569 RS02695
gene id: 568768:Dpoa569_RS02695
uniprot id: A0A5B8HGL5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

568768:Dpoa569 RS14935
gene id: 568768:Dpoa569_RS14935
uniprot id: A0A5B8HR15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

568768:Dpoa569 RS12645
gene id: 568768:Dpoa569_RS12645
uniprot id: A0A5B8HPW7
names: Similarity
messages: Belongs to the citrate synthase family.

568768:Dpoa569 RS00695
gene id: 568768:Dpoa569_RS00695
uniprot id: A0A5B8I0H4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS16375
gene id: 568768:Dpoa569_RS16375
uniprot id: A0A5B8ICT7
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS09240
gene id: 568768:Dpoa569_RS09240
uniprot id: A0A5B8I6C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

568768:Dpoa569 RS04880
gene id: 568768:Dpoa569_RS04880
uniprot id: A0A5B8HJ13
names: Caution
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS14640
gene id: 568768:Dpoa569_RS14640
uniprot id: A0A5B8IES4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS04090
gene id: 568768:Dpoa569_RS04090
uniprot id: A0A5B8I360
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

568768:Dpoa569 RS08160
gene id: 568768:Dpoa569_RS08160
uniprot id: A0A5B8HJ76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane
messages: Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.

568768:Dpoa569 RS12440
gene id: 568768:Dpoa569_RS12440
uniprot id: A0A5B8I6S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

568768:Dpoa569 RS11815
gene id: 568768:Dpoa569_RS11815
uniprot id: A0A5B8HP64
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS02205
gene id: 568768:Dpoa569_RS02205
uniprot id: A0A5B8I6N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

568768:Dpoa569 RS09455
gene id: 568768:Dpoa569_RS09455
uniprot id: A0A5B8I4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS04000
gene id: 568768:Dpoa569_RS04000
uniprot id: A0A5B8I7C4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

568768:Dpoa569 RS10390
gene id: 568768:Dpoa569_RS10390
uniprot id: A0A5B8I824
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

568768:Dpoa569 RS11435
gene id: 568768:Dpoa569_RS11435
uniprot id: A0A5B8I9L4
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS02525
gene id: 568768:Dpoa569_RS02525
uniprot id: A0A5B8I1U3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

568768:Dpoa569 RS12285
gene id: 568768:Dpoa569_RS12285
uniprot id: A0A5B8I8A1
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

568768:Dpoa569 RS02805
gene id: 568768:Dpoa569_RS02805
uniprot id: A0A5B8HGT1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

568768:Dpoa569 RS04675
gene id: 568768:Dpoa569_RS04675
uniprot id: A0A5B8I3H8
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.

568768:Dpoa569 RS02170
gene id: 568768:Dpoa569_RS02170
uniprot id: A0A5B8I1J8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

568768:Dpoa569 RS09155
gene id: 568768:Dpoa569_RS09155
uniprot id: A0A5B8HM52
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

568768:Dpoa569 RS10135
gene id: 568768:Dpoa569_RS10135
uniprot id: A0A5B8IDG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

568768:Dpoa569 RS07490
gene id: 568768:Dpoa569_RS07490
uniprot id: A0A5B8HIN6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

568768:Dpoa569 RS01885
gene id: 568768:Dpoa569_RS01885
uniprot id: A0A5B8I6F7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

568768:Dpoa569 RS03255
gene id: 568768:Dpoa569_RS03255
uniprot id: A0A5B8I7B8
names: Similarity
messages: Belongs to the UPF0231 family.

568768:Dpoa569 RS14975
gene id: 568768:Dpoa569_RS14975
uniprot id: A0A5B8IEY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS11885
gene id: 568768:Dpoa569_RS11885
uniprot id: A0A5B8HP81
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS10510
gene id: 568768:Dpoa569_RS10510
uniprot id: A0A5B8I5K5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

568768:Dpoa569 RS15150
gene id: 568768:Dpoa569_RS15150
uniprot id: A0A5B8HVA4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

568768:Dpoa569 RS08650
gene id: 568768:Dpoa569_RS08650
uniprot id: A0A5B8I7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS12830
gene id: 568768:Dpoa569_RS12830
uniprot id: A0A5B8HMY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

568768:Dpoa569 RS11130
gene id: 568768:Dpoa569_RS11130
uniprot id: A0A5B8I7G3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

568768:Dpoa569 RS09740
gene id: 568768:Dpoa569_RS09740
uniprot id: A0A5B8ID28
names: Similarity
messages: Belongs to the peptidase S49 family.

568768:Dpoa569 RS12765
gene id: 568768:Dpoa569_RS12765
uniprot id: A0A5B8IFA8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

568768:Dpoa569 RS05795
gene id: 568768:Dpoa569_RS05795
uniprot id: A0A5B8I491
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

568768:Dpoa569 RS13855
gene id: 568768:Dpoa569_RS13855
uniprot id: A0A5B8IE88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

568768:Dpoa569 RS07980
gene id: 568768:Dpoa569_RS07980
uniprot id: A0A5B8I5K0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS07825
gene id: 568768:Dpoa569_RS07825
uniprot id: A0A5B8HIX6
names: Similarity
messages: Belongs to the SufE family.

568768:Dpoa569 RS18730
gene id: 568768:Dpoa569_RS18730
uniprot id: A0A5B8HU42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

568768:Dpoa569 RS16130
gene id: 568768:Dpoa569_RS16130
uniprot id: A0A5B8II00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

568768:Dpoa569 RS18740
gene id: 568768:Dpoa569_RS18740
uniprot id: A0A5B8IE95
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

568768:Dpoa569 RS01365
gene id: 568768:Dpoa569_RS01365
uniprot id: A0A5B8HFL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

568768:Dpoa569 RS09535
gene id: 568768:Dpoa569_RS09535
uniprot id: A0A5B8IBA9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10B family.
messages: Binds 1 zinc ion per subunit.

568768:Dpoa569 RS08955
gene id: 568768:Dpoa569_RS08955
uniprot id: A0A5B8I618
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

568768:Dpoa569 RS04740
gene id: 568768:Dpoa569_RS04740
uniprot id: A0A5B8I3F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

568768:Dpoa569 RS07170
gene id: 568768:Dpoa569_RS07170
uniprot id: A0A5B8I9N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

568768:Dpoa569 RS15945
gene id: 568768:Dpoa569_RS15945
uniprot id: A0A5B8HS89
names: Similarity
messages: Belongs to the CFA/CMAS family.

568768:Dpoa569 RS13970
gene id: 568768:Dpoa569_RS13970
uniprot id: A0A5B8HQI1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS13540
gene id: 568768:Dpoa569_RS13540
uniprot id: A0A5B8I9F8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

568768:Dpoa569 RS00295
gene id: 568768:Dpoa569_RS00295
uniprot id: A0A5B8I082
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

568768:Dpoa569 RS04850
gene id: 568768:Dpoa569_RS04850
uniprot id: A0A5B8I3N1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB.

568768:Dpoa569 RS01745
gene id: 568768:Dpoa569_RS01745
uniprot id: A0A5B8I189
names: Similarity
messages: Belongs to the disproportionating enzyme family.

568768:Dpoa569 RS13145
gene id: 568768:Dpoa569_RS13145
uniprot id: A0A5B8ID61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

568768:Dpoa569 RS13615
gene id: 568768:Dpoa569_RS13615
uniprot id: A0A5B8HQP1
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

568768:Dpoa569 RS14970
gene id: 568768:Dpoa569_RS14970
uniprot id: A0A5B8HRP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS18455
gene id: 568768:Dpoa569_RS18455
uniprot id: A0A5B8HRP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Belongs to the flavodoxin family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

568768:Dpoa569 RS15100
gene id: 568768:Dpoa569_RS15100
uniprot id: A0A5B8I8L9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

568768:Dpoa569 RS05390
gene id: 568768:Dpoa569_RS05390
uniprot id: A0A5B8I2B4
names: Similarity
messages: Belongs to the isochorismate synthase family.

568768:Dpoa569 RS01930
gene id: 568768:Dpoa569_RS01930
uniprot id: A0A5B8HG35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

568768:Dpoa569 RS02600
gene id: 568768:Dpoa569_RS02600
uniprot id: A0A5B8I285
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

568768:Dpoa569 RS02725
gene id: 568768:Dpoa569_RS02725
uniprot id: A0A5B8I0A0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

568768:Dpoa569 RS00530
gene id: 568768:Dpoa569_RS00530
uniprot id: A0A5B8I0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

568768:Dpoa569 RS07460
gene id: 568768:Dpoa569_RS07460
uniprot id: A0A5B8HKN7
names: Similarity
messages: Belongs to the fabD family.

568768:Dpoa569 RS09835
gene id: 568768:Dpoa569_RS09835
uniprot id: A0A5B8ID63
names: Similarity
messages: Belongs to the YciI family.

568768:Dpoa569 RS02320
gene id: 568768:Dpoa569_RS02320
uniprot id: A0A5B8I1W5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

568768:Dpoa569 RS12200
gene id: 568768:Dpoa569_RS12200
uniprot id: A0A5B8ID55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

568768:Dpoa569 RS11615
gene id: 568768:Dpoa569_RS11615
uniprot id: A0A5B8HN51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

568768:Dpoa569 RS04385
gene id: 568768:Dpoa569_RS04385
uniprot id: A0A5B8I3D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

568768:Dpoa569 RS09870
gene id: 568768:Dpoa569_RS09870
uniprot id: A0A5B8IBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS17770
gene id: 568768:Dpoa569_RS17770
uniprot id: A0A5B8IBM1
names: Similarity
messages: Belongs to the RutC family.

568768:Dpoa569 RS01005
gene id: 568768:Dpoa569_RS01005
uniprot id: A0A5B8HE20
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS15765
gene id: 568768:Dpoa569_RS15765
uniprot id: A0A5B8HQ37
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

568768:Dpoa569 RS10015
gene id: 568768:Dpoa569_RS10015
uniprot id: A0A5B8HKG5
names: Similarity
messages: Belongs to the UPF0229 family.

568768:Dpoa569 RS03625
gene id: 568768:Dpoa569_RS03625
uniprot id: A0A5B8HI14
names: Similarity
messages: Belongs to the YggT family.

568768:Dpoa569 RS16780
gene id: 568768:Dpoa569_RS16780
uniprot id: A0A5B8HS06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

568768:Dpoa569 RS05110
gene id: 568768:Dpoa569_RS05110
uniprot id: A0A5B8I3T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

568768:Dpoa569 RS07185
gene id: 568768:Dpoa569_RS07185
uniprot id: A0A5B8IBA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

568768:Dpoa569 RS10115
gene id: 568768:Dpoa569_RS10115
uniprot id: A0A5B8HMX6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

568768:Dpoa569 RS02210
gene id: 568768:Dpoa569_RS02210
uniprot id: A0A5B8I1T9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

568768:Dpoa569 RS07595
gene id: 568768:Dpoa569_RS07595
uniprot id: A0A5B8I556
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

568768:Dpoa569 RS18140
gene id: 568768:Dpoa569_RS18140
uniprot id: A0A5B8IBV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

568768:Dpoa569 RS09715
gene id: 568768:Dpoa569_RS09715
uniprot id: A0A5B8HMK3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS05655
gene id: 568768:Dpoa569_RS05655
uniprot id: A0A5B8HJ30
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedD family.
messages: Cell inner membrane
messages: Non-essential cell division protein that could be required for efficient cell constriction.
messages: The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.

568768:Dpoa569 RS05310
gene id: 568768:Dpoa569_RS05310
uniprot id: A0A5B8I5R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

568768:Dpoa569 RS08615
gene id: 568768:Dpoa569_RS08615
uniprot id: A0A5B8I4D8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

568768:Dpoa569 RS01535
gene id: 568768:Dpoa569_RS01535
uniprot id: A0A5B8HEF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS13025
gene id: 568768:Dpoa569_RS13025
uniprot id: A0A5B8I949
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaA family. HdA subfamily.
messages: Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.
messages: The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).

568768:Dpoa569 RS13555
gene id: 568768:Dpoa569_RS13555
uniprot id: A0A5B8HQI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

568768:Dpoa569 RS01105
gene id: 568768:Dpoa569_RS01105
uniprot id: A0A5B8I0X6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS02940
gene id: 568768:Dpoa569_RS02940
uniprot id: A0A5B8I289
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

568768:Dpoa569 RS19345
gene id: 568768:Dpoa569_RS19345
uniprot id: A0A5B8HTF9
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

568768:Dpoa569 RS00685
gene id: 568768:Dpoa569_RS00685
uniprot id: A0A5B8I0N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

568768:Dpoa569 RS08920
gene id: 568768:Dpoa569_RS08920
uniprot id: A0A5B8I5Z6
names: Subcellular Location Annotation
messages: Cell inner membrane

568768:Dpoa569 RS07500
gene id: 568768:Dpoa569_RS07500
uniprot id: A0A5B8I9Y9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

568768:Dpoa569 RS18285
gene id: 568768:Dpoa569_RS18285
uniprot id: A0A5B8HSU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

568768:Dpoa569 RS03395
gene id: 568768:Dpoa569_RS03395
uniprot id: A0A5B8HH96
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS02965
gene id: 568768:Dpoa569_RS02965
uniprot id: A0A5B8I2H7
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

568768:Dpoa569 RS04685
gene id: 568768:Dpoa569_RS04685
uniprot id: A0A5B8I3J5
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

568768:Dpoa569 RS14705
gene id: 568768:Dpoa569_RS14705
uniprot id: A0A5B8IGT0
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS01100
gene id: 568768:Dpoa569_RS01100
uniprot id: A0A5B8HE36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

568768:Dpoa569 RS01420
gene id: 568768:Dpoa569_RS01420
uniprot id: A0A5B8I5Q8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.

568768:Dpoa569 RS17690
gene id: 568768:Dpoa569_RS17690
uniprot id: A0A5B8HR81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

568768:Dpoa569 RS01360
gene id: 568768:Dpoa569_RS01360
uniprot id: A0A5B8HEC4
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

568768:Dpoa569 RS19055
gene id: 568768:Dpoa569_RS19055
uniprot id: A0A5B8IKG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

568768:Dpoa569 RS13965
gene id: 568768:Dpoa569_RS13965
uniprot id: A0A5B8IB89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

568768:Dpoa569 RS16175
gene id: 568768:Dpoa569_RS16175
uniprot id: A0A5B8HSD8
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.

568768:Dpoa569 RS04840
gene id: 568768:Dpoa569_RS04840
uniprot id: A0A5B8IL38
names: Subcellular Location Annotation
messages: Cell inner membrane

568768:Dpoa569 RS05745
gene id: 568768:Dpoa569_RS05745
uniprot id: A0A5B8I478
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS17150
gene id: 568768:Dpoa569_RS17150
uniprot id: A0A5B8HT13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

568768:Dpoa569 RS18315
gene id: 568768:Dpoa569_RS18315
uniprot id: A0A5B8IBN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

568768:Dpoa569 RS05885
gene id: 568768:Dpoa569_RS05885
uniprot id: A0A5B8I4B1
names: Similarity
messages: Belongs to the HupF/HypC family.

568768:Dpoa569 RS16480
gene id: 568768:Dpoa569_RS16480
uniprot id: A0A5B8HSK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

568768:Dpoa569 RS18560
gene id: 568768:Dpoa569_RS18560
uniprot id: A0A5B8IBT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

568768:Dpoa569 RS13370
gene id: 568768:Dpoa569_RS13370
uniprot id: A0A5B8IFU8
names: Similarity
messages: Belongs to the P(II) protein family.

568768:Dpoa569 RS09795
gene id: 568768:Dpoa569_RS09795
uniprot id: A0A5B8I522
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

568768:Dpoa569 RS10820
gene id: 568768:Dpoa569_RS10820
uniprot id: A0A5B8HNH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
messages: Cell membrane
messages: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
messages: Membrane

568768:Dpoa569 RS07145
gene id: 568768:Dpoa569_RS07145
uniprot id: A0A5B8I3F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

568768:Dpoa569 RS04115
gene id: 568768:Dpoa569_RS04115
uniprot id: A0A5B8I3C7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

568768:Dpoa569 RS08325
gene id: 568768:Dpoa569_RS08325
uniprot id: A0A5B8I5K8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

568768:Dpoa569 RS13430
gene id: 568768:Dpoa569_RS13430
uniprot id: A0A5B8I7D4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

568768:Dpoa569 RS00975
gene id: 568768:Dpoa569_RS00975
uniprot id: A0A5B8I0N8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

568768:Dpoa569 RS09815
gene id: 568768:Dpoa569_RS09815
uniprot id: A0A5B8HMN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS15890
gene id: 568768:Dpoa569_RS15890
uniprot id: A0A5B8HS79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.
messages: Membrane

568768:Dpoa569 RS04030
gene id: 568768:Dpoa569_RS04030
uniprot id: A0A5B8I345
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

568768:Dpoa569 RS03025
gene id: 568768:Dpoa569_RS03025
uniprot id: A0A5B8HHI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

568768:Dpoa569 RS04175
gene id: 568768:Dpoa569_RS04175
uniprot id: A0A5B8HGA5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

568768:Dpoa569 RS15490
gene id: 568768:Dpoa569_RS15490
uniprot id: A0A5B8I8T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS03885
gene id: 568768:Dpoa569_RS03885
uniprot id: A0A5B8HHN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

568768:Dpoa569 RS16675
gene id: 568768:Dpoa569_RS16675
uniprot id: A0A5B8IAV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

568768:Dpoa569 RS16620
gene id: 568768:Dpoa569_RS16620
uniprot id: A0A5B8IAU1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

568768:Dpoa569 RS10580
gene id: 568768:Dpoa569_RS10580
uniprot id: A0A5B8HL59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

568768:Dpoa569 RS00495
gene id: 568768:Dpoa569_RS00495
uniprot id: A0A5B8HDU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

568768:Dpoa569 RS00600
gene id: 568768:Dpoa569_RS00600
uniprot id: A0A5B8HDX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

568768:Dpoa569 RS09045
gene id: 568768:Dpoa569_RS09045
uniprot id: A0A5B8I7Y2
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS16880
gene id: 568768:Dpoa569_RS16880
uniprot id: A0A5B8ID44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

568768:Dpoa569 RS10530
gene id: 568768:Dpoa569_RS10530
uniprot id: A0A5B8HL48
names: Function
names: Similarity
messages: Belongs to the TorD/DmsD family. DmsD subfamily.
messages: Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein.

568768:Dpoa569 RS10410
gene id: 568768:Dpoa569_RS10410
uniprot id: A0A5B8I5H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

568768:Dpoa569 RS01790
gene id: 568768:Dpoa569_RS01790
uniprot id: A0A5B8I197
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

568768:Dpoa569 RS12475
gene id: 568768:Dpoa569_RS12475
uniprot id: A0A5B8HPM6
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

568768:Dpoa569 RS12870
gene id: 568768:Dpoa569_RS12870
uniprot id: A0A5B8I905
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

568768:Dpoa569 RS16825
gene id: 568768:Dpoa569_RS16825
uniprot id: A0A5B8IIG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

568768:Dpoa569 RS11595
gene id: 568768:Dpoa569_RS11595
uniprot id: A0A5B8IEE2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

568768:Dpoa569 RS03435
gene id: 568768:Dpoa569_RS03435
uniprot id: A0A5B8I0T0
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

568768:Dpoa569 RS17550
gene id: 568768:Dpoa569_RS17550
uniprot id: A0A5B8IBU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

568768:Dpoa569 RS18580
gene id: 568768:Dpoa569_RS18580
uniprot id: A0A5B8IE60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

568768:Dpoa569 RS13475
gene id: 568768:Dpoa569_RS13475
uniprot id: A0A5B8HT00
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

568768:Dpoa569 RS19060
gene id: 568768:Dpoa569_RS19060
uniprot id: A0A5B8IEH9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

568768:Dpoa569 RS18765
gene id: 568768:Dpoa569_RS18765
uniprot id: A0A5B8IAY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

568768:Dpoa569 RS02925
gene id: 568768:Dpoa569_RS02925
uniprot id: A0A5B8I751
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

568768:Dpoa569 RS09215
gene id: 568768:Dpoa569_RS09215
uniprot id: A0A5B8HM68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

568768:Dpoa569 RS17705
gene id: 568768:Dpoa569_RS17705
uniprot id: A0A5B8IDL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

568768:Dpoa569 RS17070
gene id: 568768:Dpoa569_RS17070
uniprot id: A0A5B8IBK0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

568768:Dpoa569 RS01695
gene id: 568768:Dpoa569_RS01695
uniprot id: A0A5B8HEJ6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

568768:Dpoa569 RS03085
gene id: 568768:Dpoa569_RS03085
uniprot id: A0A5B8I782
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

568768:Dpoa569 RS09405
gene id: 568768:Dpoa569_RS09405
uniprot id: A0A5B8I6G6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

568768:Dpoa569 RS13890
gene id: 568768:Dpoa569_RS13890
uniprot id: A0A5B8I9L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

568768:Dpoa569 RS01690
gene id: 568768:Dpoa569_RS01690
uniprot id: A0A5B8IBE9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

568768:Dpoa569 RS12580
gene id: 568768:Dpoa569_RS12580
uniprot id: A0A5B8I8T5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

568768:Dpoa569 RS05525
gene id: 568768:Dpoa569_RS05525
uniprot id: A0A5B8IDE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

568768:Dpoa569 RS12180
gene id: 568768:Dpoa569_RS12180
uniprot id: A0A5B8I8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

568768:Dpoa569 RS07575
gene id: 568768:Dpoa569_RS07575
uniprot id: A0A5B8I592
names: Similarity
messages: Belongs to the heat shock protein 70 family.

568768:Dpoa569 RS04320
gene id: 568768:Dpoa569_RS04320
uniprot id: A0A5B8I3A4
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS02730
gene id: 568768:Dpoa569_RS02730
uniprot id: A0A5B8I1Z8
names: Caution
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. GpmB subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS00120
gene id: 568768:Dpoa569_RS00120
uniprot id: A0A5Q2V719
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

568768:Dpoa569 RS12665
gene id: 568768:Dpoa569_RS12665
uniprot id: A0A5B8IF72
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

568768:Dpoa569 RS08995
gene id: 568768:Dpoa569_RS08995
uniprot id: A0A5B8HM01
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

568768:Dpoa569 RS09930
gene id: 568768:Dpoa569_RS09930
uniprot id: A0A5B8ID83
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

568768:Dpoa569 RS10190
gene id: 568768:Dpoa569_RS10190
uniprot id: A0A5B8I6U4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS07580
gene id: 568768:Dpoa569_RS07580
uniprot id: A0A5B8I3Q8
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS12170
gene id: 568768:Dpoa569_RS12170
uniprot id: A0A5B8I876
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DyP-type peroxidase family. EfeB subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.
messages: Periplasm

568768:Dpoa569 RS14120
gene id: 568768:Dpoa569_RS14120
uniprot id: A0A5B8I969
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

568768:Dpoa569 RS05335
gene id: 568768:Dpoa569_RS05335
uniprot id: A0A5B8I3Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS04455
gene id: 568768:Dpoa569_RS04455
uniprot id: A0A5B8I812
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

568768:Dpoa569 RS12100
gene id: 568768:Dpoa569_RS12100
uniprot id: A0A5B8ID21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS09200
gene id: 568768:Dpoa569_RS09200
uniprot id: A0A5B8HM67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

568768:Dpoa569 RS17885
gene id: 568768:Dpoa569_RS17885
uniprot id: A0A5B8IC09
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

568768:Dpoa569 RS16020
gene id: 568768:Dpoa569_RS16020
uniprot id: A0A5B8IAI0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.
messages: Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.

568768:Dpoa569 RS10565
gene id: 568768:Dpoa569_RS10565
uniprot id: A0A5B8I5L6
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS09230
gene id: 568768:Dpoa569_RS09230
uniprot id: A0A5B8I4N9
names: Similarity
messages: Belongs to the UPF0260 family.

568768:Dpoa569 RS13995
gene id: 568768:Dpoa569_RS13995
uniprot id: A0A5B8I947
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

568768:Dpoa569 RS15315
gene id: 568768:Dpoa569_RS15315
uniprot id: A0A5B8I8Q0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

568768:Dpoa569 RS01325
gene id: 568768:Dpoa569_RS01325
uniprot id: A0A5B8I0W0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS13410
gene id: 568768:Dpoa569_RS13410
uniprot id: A0A5B8IAR9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

568768:Dpoa569 RS00365
gene id: 568768:Dpoa569_RS00365
uniprot id: A0A5B8I5H5
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.
messages: Monomer.

568768:Dpoa569 RS17370
gene id: 568768:Dpoa569_RS17370
uniprot id: A0A5B8IBQ9
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

568768:Dpoa569 RS16800
gene id: 568768:Dpoa569_RS16800
uniprot id: A0A5B8IBD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

568768:Dpoa569 RS10650
gene id: 568768:Dpoa569_RS10650
uniprot id: A0A5B8I962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

568768:Dpoa569 RS03535
gene id: 568768:Dpoa569_RS03535
uniprot id: A0A5B8I2R6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS15285
gene id: 568768:Dpoa569_RS15285
uniprot id: A0A5B8HRV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

568768:Dpoa569 RS00135
gene id: 568768:Dpoa569_RS00135
uniprot id: A0A5B8HYA2
names: Similarity
names: Subunit
messages: Belongs to the ViaA family.
messages: Possible formation of a ternary complex RavA-ViaA-CadA.

568768:Dpoa569 RS18885
gene id: 568768:Dpoa569_RS18885
uniprot id: A0A5B8HRY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS16555
gene id: 568768:Dpoa569_RS16555
uniprot id: A0A5B8II80
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

568768:Dpoa569 RS08985
gene id: 568768:Dpoa569_RS08985
uniprot id: A0A5B8IAX6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS04445
gene id: 568768:Dpoa569_RS04445
uniprot id: A0A5B8I535
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

568768:Dpoa569 RS13645
gene id: 568768:Dpoa569_RS13645
uniprot id: A0A5B8I7I2
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

568768:Dpoa569 RS00895
gene id: 568768:Dpoa569_RS00895
uniprot id: A0A5B8HDZ4
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

568768:Dpoa569 RS02800
gene id: 568768:Dpoa569_RS02800
uniprot id: A0A5B8HFC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

568768:Dpoa569 RS02355
gene id: 568768:Dpoa569_RS02355
uniprot id: A0A5B8I1P9
names: Similarity
messages: Belongs to the aspartokinase family.

568768:Dpoa569 RS18630
gene id: 568768:Dpoa569_RS18630
uniprot id: A0A5B8IE70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

568768:Dpoa569 RS03670
gene id: 568768:Dpoa569_RS03670
uniprot id: A0A5B8I2P7
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.

568768:Dpoa569 RS00605
gene id: 568768:Dpoa569_RS00605
uniprot id: A0A5B8HF28
names: Similarity
messages: Belongs to the peptidase M16 family.

568768:Dpoa569 RS01710
gene id: 568768:Dpoa569_RS01710
uniprot id: A0A5B8I171
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS13720
gene id: 568768:Dpoa569_RS13720
uniprot id: A0A5B8IE67
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS17965
gene id: 568768:Dpoa569_RS17965
uniprot id: A0A5B8IDQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS02750
gene id: 568768:Dpoa569_RS02750
uniprot id: A0A5B8I6I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS00345
gene id: 568768:Dpoa569_RS00345
uniprot id: A0A5B8HEX2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

568768:Dpoa569 RS09825
gene id: 568768:Dpoa569_RS09825
uniprot id: A0A5B8I8E8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

568768:Dpoa569 RS04710
gene id: 568768:Dpoa569_RS04710
uniprot id: A0A5B8I5D3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

568768:Dpoa569 RS12385
gene id: 568768:Dpoa569_RS12385
uniprot id: A0A5B8I8C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

568768:Dpoa569 RS04545
gene id: 568768:Dpoa569_RS04545
uniprot id: A0A5B8I561
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

568768:Dpoa569 RS02540
gene id: 568768:Dpoa569_RS02540
uniprot id: A0A5B8HGH9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

568768:Dpoa569 RS09185
gene id: 568768:Dpoa569_RS09185
uniprot id: A0A5B8I6B2
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

568768:Dpoa569 RS02660
gene id: 568768:Dpoa569_RS02660
uniprot id: A0A5B8HGL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

568768:Dpoa569 RS10955
gene id: 568768:Dpoa569_RS10955
uniprot id: A0A5B8I5U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

568768:Dpoa569 RS07220
gene id: 568768:Dpoa569_RS07220
uniprot id: A0A5B8HK75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

568768:Dpoa569 RS13545
gene id: 568768:Dpoa569_RS13545
uniprot id: A0A5B8I8W6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

568768:Dpoa569 RS07695
gene id: 568768:Dpoa569_RS07695
uniprot id: A0A5B8I3T2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

568768:Dpoa569 RS19075
gene id: 568768:Dpoa569_RS19075
uniprot id: A0A5B8ILZ0
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

568768:Dpoa569 RS07770
gene id: 568768:Dpoa569_RS07770
uniprot id: A0A5B8HKS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

568768:Dpoa569 RS17235
gene id: 568768:Dpoa569_RS17235
uniprot id: A0A5B8HS83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

568768:Dpoa569 RS02955
gene id: 568768:Dpoa569_RS02955
uniprot id: A0A5B8HGY2
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

568768:Dpoa569 RS10935
gene id: 568768:Dpoa569_RS10935
uniprot id: A0A5B8I9B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

568768:Dpoa569 RS03715
gene id: 568768:Dpoa569_RS03715
uniprot id: A0A5B8I2W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

568768:Dpoa569 RS15660
gene id: 568768:Dpoa569_RS15660
uniprot id: A0A5B8HS40
names: Subcellular Location Annotation
messages: Cell inner membrane

568768:Dpoa569 RS15460
gene id: 568768:Dpoa569_RS15460
uniprot id: A0A5B8HRZ8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

568768:Dpoa569 RS15715
gene id: 568768:Dpoa569_RS15715
uniprot id: A0A5B8HQ29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

568768:Dpoa569 RS02345
gene id: 568768:Dpoa569_RS02345
uniprot id: A0A5B8HTN3
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

568768:Dpoa569 RS03055
gene id: 568768:Dpoa569_RS03055
uniprot id: A0A5B8I2A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

568768:Dpoa569 RS02140
gene id: 568768:Dpoa569_RS02140
uniprot id: A0A5B8I649
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

568768:Dpoa569 RS15185
gene id: 568768:Dpoa569_RS15185
uniprot id: A0A5B8IA18
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

568768:Dpoa569 RS05135
gene id: 568768:Dpoa569_RS05135
uniprot id: A0A5B8HIN9
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS03075
gene id: 568768:Dpoa569_RS03075
uniprot id: A0A5B8I2K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

568768:Dpoa569 RS19230
gene id: 568768:Dpoa569_RS19230
uniprot id: A0A5B8IKL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS04705
gene id: 568768:Dpoa569_RS04705
uniprot id: A0A5B8I7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

568768:Dpoa569 RS16590
gene id: 568768:Dpoa569_RS16590
uniprot id: A0A5B8HQL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

568768:Dpoa569 RS16515
gene id: 568768:Dpoa569_RS16515
uniprot id: A0A5B8IB78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

568768:Dpoa569 RS07330
gene id: 568768:Dpoa569_RS07330
uniprot id: A0A5B8HIJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

568768:Dpoa569 RS10090
gene id: 568768:Dpoa569_RS10090
uniprot id: A0A5B8I6R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.
messages: Cell inner membrane

568768:Dpoa569 RS04485
gene id: 568768:Dpoa569_RS04485
uniprot id: A0A5B8HI52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

568768:Dpoa569 RS15635
gene id: 568768:Dpoa569_RS15635
uniprot id: A0A5B8IAA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

568768:Dpoa569 RS07995
gene id: 568768:Dpoa569_RS07995
uniprot id: A0A5B8HJ28
names: Similarity
messages: Belongs to the SUI1 family.

568768:Dpoa569 RS11250
gene id: 568768:Dpoa569_RS11250
uniprot id: A0A5B8HNT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

568768:Dpoa569 RS01975
gene id: 568768:Dpoa569_RS01975
uniprot id: A0A5B8HER7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

568768:Dpoa569 RS01335
gene id: 568768:Dpoa569_RS01335
uniprot id: A0A5B8I620
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS12970
gene id: 568768:Dpoa569_RS12970
uniprot id: A0A5B8I737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0370 family.
messages: Cell membrane

568768:Dpoa569 RS01865
gene id: 568768:Dpoa569_RS01865
uniprot id: A0A5B8HSB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

568768:Dpoa569 RS03385
gene id: 568768:Dpoa569_RS03385
uniprot id: A0A5B8I2H5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

568768:Dpoa569 RS00955
gene id: 568768:Dpoa569_RS00955
uniprot id: A0A5B8I5U4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

568768:Dpoa569 RS14030
gene id: 568768:Dpoa569_RS14030
uniprot id: A0A5B8HQJ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: Homohexamer.

568768:Dpoa569 RS07675
gene id: 568768:Dpoa569_RS07675
uniprot id: A0A5B8HKT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

568768:Dpoa569 RS18415
gene id: 568768:Dpoa569_RS18415
uniprot id: A0A5B8IAS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS17810
gene id: 568768:Dpoa569_RS17810
uniprot id: A0A5B8IDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS07355
gene id: 568768:Dpoa569_RS07355
uniprot id: A0A5B8IBD8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS13945
gene id: 568768:Dpoa569_RS13945
uniprot id: A0A5B8IC01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

568768:Dpoa569 RS18290
gene id: 568768:Dpoa569_RS18290
uniprot id: A0A5B8IJV8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS09275
gene id: 568768:Dpoa569_RS09275
uniprot id: A0A5B8ICT6
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

568768:Dpoa569 RS16395
gene id: 568768:Dpoa569_RS16395
uniprot id: A0A5B8I9B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-modifying YgfZ family.
messages: Cytoplasm
messages: Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.

568768:Dpoa569 RS16120
gene id: 568768:Dpoa569_RS16120
uniprot id: A0A5B8ICM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS16500
gene id: 568768:Dpoa569_RS16500
uniprot id: A0A5B8II68
names: Similarity
messages: Belongs to the UPF0213 family.

568768:Dpoa569 RS04860
gene id: 568768:Dpoa569_RS04860
uniprot id: A0A5B8HGP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC.

568768:Dpoa569 RS07565
gene id: 568768:Dpoa569_RS07565
uniprot id: A0A5B8HKR1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

568768:Dpoa569 RS15270
gene id: 568768:Dpoa569_RS15270
uniprot id: A0A5B8IAE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

568768:Dpoa569 RS18355
gene id: 568768:Dpoa569_RS18355
uniprot id: A0A5B8IAR1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

568768:Dpoa569 RS11775
gene id: 568768:Dpoa569_RS11775
uniprot id: A0A5B8I7V3
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

568768:Dpoa569 RS02875
gene id: 568768:Dpoa569_RS02875
uniprot id: A0A5B8I736
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

568768:Dpoa569 RS07905
gene id: 568768:Dpoa569_RS07905
uniprot id: A0A5B8HKZ6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

568768:Dpoa569 RS15625
gene id: 568768:Dpoa569_RS15625
uniprot id: A0A5B8HRF1
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS03615
gene id: 568768:Dpoa569_RS03615
uniprot id: A0A5B8I740
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

568768:Dpoa569 RS09695
gene id: 568768:Dpoa569_RS09695
uniprot id: A0A5B8I502
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

568768:Dpoa569 RS11585
gene id: 568768:Dpoa569_RS11585
uniprot id: A0A5B8I9P6
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

568768:Dpoa569 RS03920
gene id: 568768:Dpoa569_RS03920
uniprot id: A0A5B8I302
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

568768:Dpoa569 RS12890
gene id: 568768:Dpoa569_RS12890
uniprot id: A0A5B8IDJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

568768:Dpoa569 RS03755
gene id: 568768:Dpoa569_RS03755
uniprot id: A0A5B8I2W6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

568768:Dpoa569 RS06790
gene id: 568768:Dpoa569_RS06790
uniprot id: A0A5B8I4R3
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

568768:Dpoa569 RS07835
gene id: 568768:Dpoa569_RS07835
uniprot id: A0A5B8IA70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

568768:Dpoa569 RS18405
gene id: 568768:Dpoa569_RS18405
uniprot id: A0A5B8IC22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS07235
gene id: 568768:Dpoa569_RS07235
uniprot id: A0A5B8HKI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliT family.
messages: Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
messages: Homodimer. Interacts with FliD and FlhC.
messages: cytosol

568768:Dpoa569 RS00790
gene id: 568768:Dpoa569_RS00790
uniprot id: A0A5B8I5Q9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

568768:Dpoa569 RS18015
gene id: 568768:Dpoa569_RS18015
uniprot id: A0A5B8HVF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

568768:Dpoa569 RS10795
gene id: 568768:Dpoa569_RS10795
uniprot id: A0A5B8I7A8
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

568768:Dpoa569 RS13955
gene id: 568768:Dpoa569_RS13955
uniprot id: A0A5B8HQX0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

568768:Dpoa569 RS00115
gene id: 568768:Dpoa569_RS00115
uniprot id: A0A5Q2V5J8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

568768:Dpoa569 RS09985
gene id: 568768:Dpoa569_RS09985
uniprot id: A0A5B8HMS6
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

568768:Dpoa569 RS11335
gene id: 568768:Dpoa569_RS11335
uniprot id: A0A5B8I7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS04855
gene id: 568768:Dpoa569_RS04855
uniprot id: A0A5B8I3H3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC.

568768:Dpoa569 RS16775
gene id: 568768:Dpoa569_RS16775
uniprot id: A0A5B8ID13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS08245
gene id: 568768:Dpoa569_RS08245
uniprot id: A0A5B8IC29
names: Subcellular Location Annotation
messages: Cell inner membrane

568768:Dpoa569 RS00555
gene id: 568768:Dpoa569_RS00555
uniprot id: A0A5B8HF21
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

568768:Dpoa569 RS02350
gene id: 568768:Dpoa569_RS02350
uniprot id: A0A5B8I014
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS12905
gene id: 568768:Dpoa569_RS12905
uniprot id: A0A5B8IFE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

568768:Dpoa569 RS00305
gene id: 568768:Dpoa569_RS00305
uniprot id: A0A5B8I5F7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS09150
gene id: 568768:Dpoa569_RS09150
uniprot id: A0A5B8I806
names: Similarity
messages: Belongs to the UPF0053 family.

568768:Dpoa569 RS15465
gene id: 568768:Dpoa569_RS15465
uniprot id: A0A5B8IFB0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

568768:Dpoa569 RS14075
gene id: 568768:Dpoa569_RS14075
uniprot id: A0A5B8HQZ4
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

568768:Dpoa569 RS04440
gene id: 568768:Dpoa569_RS04440
uniprot id: A0A5B8I7N2
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

568768:Dpoa569 RS08010
gene id: 568768:Dpoa569_RS08010
uniprot id: A0A5B8I7D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS05155
gene id: 568768:Dpoa569_RS05155
uniprot id: A0A5B8HJ84
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

568768:Dpoa569 RS07060
gene id: 568768:Dpoa569_RS07060
uniprot id: A0A5B8HIC5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

568768:Dpoa569 RS03205
gene id: 568768:Dpoa569_RS03205
uniprot id: A0A5B8I2H9
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

568768:Dpoa569 RS04260
gene id: 568768:Dpoa569_RS04260
uniprot id: A0A5B8HIK4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

568768:Dpoa569 RS09390
gene id: 568768:Dpoa569_RS09390
uniprot id: A0A5B8ICV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

568768:Dpoa569 RS02680
gene id: 568768:Dpoa569_RS02680
uniprot id: A0A5B8I1Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

568768:Dpoa569 RS17825
gene id: 568768:Dpoa569_RS17825
uniprot id: A0A5B8IBN2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

568768:Dpoa569 RS17035
gene id: 568768:Dpoa569_RS17035
uniprot id: A0A5B8IIN5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

568768:Dpoa569 RS10595
gene id: 568768:Dpoa569_RS10595
uniprot id: A0A5B8I952
names: Subcellular Location Annotation
messages: Cytoplasm

568768:Dpoa569 RS05340
gene id: 568768:Dpoa569_RS05340
uniprot id: A0A5B8I3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

568768:Dpoa569 RS04180
gene id: 568768:Dpoa569_RS04180
uniprot id: A0A5B8HHX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

568768:Dpoa569 RS17845
gene id: 568768:Dpoa569_RS17845
uniprot id: A0A5B8HRB5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS14235
gene id: 568768:Dpoa569_RS14235
uniprot id: A0A5B8HR34
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

568768:Dpoa569 RS19255
gene id: 568768:Dpoa569_RS19255
uniprot id: A0A5B8IB83
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

568768:Dpoa569 RS06040
gene id: 568768:Dpoa569_RS06040
uniprot id: A0A5B8HHL2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

568768:Dpoa569 RS12350
gene id: 568768:Dpoa569_RS12350
uniprot id: A0A5B8I850
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS10165
gene id: 568768:Dpoa569_RS10165
uniprot id: A0A5B8HMZ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS05720
gene id: 568768:Dpoa569_RS05720
uniprot id: A0A5B8HJL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

568768:Dpoa569 RS16135
gene id: 568768:Dpoa569_RS16135
uniprot id: A0A5B8IAL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS07925
gene id: 568768:Dpoa569_RS07925
uniprot id: A0A5B8I5I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

568768:Dpoa569 RS10295
gene id: 568768:Dpoa569_RS10295
uniprot id: A0A5B8IDJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

568768:Dpoa569 RS12930
gene id: 568768:Dpoa569_RS12930
uniprot id: A0A5B8I8H3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

568768:Dpoa569 RS19040
gene id: 568768:Dpoa569_RS19040
uniprot id: A0A5B8IC63
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

568768:Dpoa569 RS10780
gene id: 568768:Dpoa569_RS10780
uniprot id: A0A5B8HU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

568768:Dpoa569 RS11280
gene id: 568768:Dpoa569_RS11280
uniprot id: A0A5B8I630
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

568768:Dpoa569 RS00160
gene id: 568768:Dpoa569_RS00160
uniprot id: A0A5B8HET0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS04420
gene id: 568768:Dpoa569_RS04420
uniprot id: A0A5B8HGF2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

568768:Dpoa569 RS09015
gene id: 568768:Dpoa569_RS09015
uniprot id: A0A5B8I4J4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

568768:Dpoa569 RS17900
gene id: 568768:Dpoa569_RS17900
uniprot id: A0A5B8HTH6
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS09890
gene id: 568768:Dpoa569_RS09890
uniprot id: A0A5B8I553
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

568768:Dpoa569 RS13960
gene id: 568768:Dpoa569_RS13960
uniprot id: A0A5B8IEB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

568768:Dpoa569 RS13015
gene id: 568768:Dpoa569_RS13015
uniprot id: A0A5B8I8U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

568768:Dpoa569 RS16550
gene id: 568768:Dpoa569_RS16550
uniprot id: A0A5B8HRW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

568768:Dpoa569 RS00940
gene id: 568768:Dpoa569_RS00940
uniprot id: A0A5B8I5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

568768:Dpoa569 RS04010
gene id: 568768:Dpoa569_RS04010
uniprot id: A0A5B8HIE1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS17995
gene id: 568768:Dpoa569_RS17995
uniprot id: A0A5B8IBF3
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

568768:Dpoa569 RS12260
gene id: 568768:Dpoa569_RS12260
uniprot id: A0A5B8HPN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

568768:Dpoa569 RS00920
gene id: 568768:Dpoa569_RS00920
uniprot id: A0A5B8I0M5
names: Similarity
messages: Belongs to the FBPase class 2 family.

568768:Dpoa569 RS05760
gene id: 568768:Dpoa569_RS05760
uniprot id: A0A5B8HJ63
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS11200
gene id: 568768:Dpoa569_RS11200
uniprot id: A0A5B8ICF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

568768:Dpoa569 RS16195
gene id: 568768:Dpoa569_RS16195
uniprot id: A0A5B8HRQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

568768:Dpoa569 RS09205
gene id: 568768:Dpoa569_RS09205
uniprot id: A0A5B8IB28
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

568768:Dpoa569 RS13975
gene id: 568768:Dpoa569_RS13975
uniprot id: A0A5B8IGA7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

568768:Dpoa569 RS00505
gene id: 568768:Dpoa569_RS00505
uniprot id: A0A5B8I577
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

568768:Dpoa569 RS11970
gene id: 568768:Dpoa569_RS11970
uniprot id: A0A5B8HPC2
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

568768:Dpoa569 RS02015
gene id: 568768:Dpoa569_RS02015
uniprot id: A0A5B8I1F9
names: Subcellular Location Annotation
messages: Cell inner membrane

568768:Dpoa569 RS13620
gene id: 568768:Dpoa569_RS13620
uniprot id: A0A5B8IE45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

568768:Dpoa569 RS01760
gene id: 568768:Dpoa569_RS01760
uniprot id: A0A5B8I5X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

568768:Dpoa569 RS00670
gene id: 568768:Dpoa569_RS00670
uniprot id: A0A5B8I0G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

568768:Dpoa569 RS00520
gene id: 568768:Dpoa569_RS00520
uniprot id: A0A5B8I5L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

568768:Dpoa569 RS01370
gene id: 568768:Dpoa569_RS01370
uniprot id: A0A5B8I5P9
names: Similarity
messages: Belongs to the thioredoxin family.

568768:Dpoa569 RS16490
gene id: 568768:Dpoa569_RS16490
uniprot id: A0A5B8ICV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

568768:Dpoa569 RS00535
gene id: 568768:Dpoa569_RS00535
uniprot id: A0A5B8HYM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS17975
gene id: 568768:Dpoa569_RS17975
uniprot id: A0A5B8IJL4
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

568768:Dpoa569 RS18530
gene id: 568768:Dpoa569_RS18530
uniprot id: A0A5B8IE51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

568768:Dpoa569 RS11950
gene id: 568768:Dpoa569_RS11950
uniprot id: A0A5B8I6F5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

568768:Dpoa569 RS03950
gene id: 568768:Dpoa569_RS03950
uniprot id: A0A5B8I7A9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS08965
gene id: 568768:Dpoa569_RS08965
uniprot id: A0A5B8I637
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS07285
gene id: 568768:Dpoa569_RS07285
uniprot id: A0A5B8I9Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

568768:Dpoa569 RS18475
gene id: 568768:Dpoa569_RS18475
uniprot id: A0A5B8IE40
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

568768:Dpoa569 RS07800
gene id: 568768:Dpoa569_RS07800
uniprot id: A0A5B8I3W2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thioesterase PaaI family.
messages: Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS10500
gene id: 568768:Dpoa569_RS10500
uniprot id: A0A5B8IDP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

568768:Dpoa569 RS01060
gene id: 568768:Dpoa569_RS01060
uniprot id: A0A5B8I0Q3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

568768:Dpoa569 RS15530
gene id: 568768:Dpoa569_RS15530
uniprot id: A0A5B8IHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS04865
gene id: 568768:Dpoa569_RS04865
uniprot id: A0A5B8HIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

568768:Dpoa569 RS02120
gene id: 568768:Dpoa569_RS02120
uniprot id: A0A5B8I1I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

568768:Dpoa569 RS09660
gene id: 568768:Dpoa569_RS09660
uniprot id: A0A5B8HMI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

568768:Dpoa569 RS02840
gene id: 568768:Dpoa569_RS02840
uniprot id: A0A5B8I223
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

568768:Dpoa569 RS05510
gene id: 568768:Dpoa569_RS05510
uniprot id: A0A5B8I429
names: Similarity
messages: Belongs to the MlaA family.

568768:Dpoa569 RS18525
gene id: 568768:Dpoa569_RS18525
uniprot id: A0A5B8IJZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

568768:Dpoa569 RS10130
gene id: 568768:Dpoa569_RS10130
uniprot id: A0A5B8HMX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

568768:Dpoa569 RS17745
gene id: 568768:Dpoa569_RS17745
uniprot id: A0A5B8HTD3
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS10065
gene id: 568768:Dpoa569_RS10065
uniprot id: A0A5B8HMV9
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

568768:Dpoa569 RS04205
gene id: 568768:Dpoa569_RS04205
uniprot id: A0A5B8HIJ3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

568768:Dpoa569 RS04310
gene id: 568768:Dpoa569_RS04310
uniprot id: A0A5B8HIL1
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

568768:Dpoa569 RS10720
gene id: 568768:Dpoa569_RS10720
uniprot id: A0A5B8IDU1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

568768:Dpoa569 RS14130
gene id: 568768:Dpoa569_RS14130
uniprot id: A0A5B8HR10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

568768:Dpoa569 RS00145
gene id: 568768:Dpoa569_RS00145
uniprot id: A0A5B8I047
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

568768:Dpoa569 RS09915
gene id: 568768:Dpoa569_RS09915
uniprot id: A0A5B8IBJ0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

568768:Dpoa569 RS02585
gene id: 568768:Dpoa569_RS02585
uniprot id: A0A5B8HF45
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

568768:Dpoa569 RS15605
gene id: 568768:Dpoa569_RS15605
uniprot id: A0A5B8HQ07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

568768:Dpoa569 RS13575
gene id: 568768:Dpoa569_RS13575
uniprot id: A0A5B8IG14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

568768:Dpoa569 RS10435
gene id: 568768:Dpoa569_RS10435
uniprot id: A0A5B8IBW4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

568768:Dpoa569 RS02880
gene id: 568768:Dpoa569_RS02880
uniprot id: A0A5B8I2A7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

568768:Dpoa569 RS13445
gene id: 568768:Dpoa569_RS13445
uniprot id: A0A5B8HNI0
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS13155
gene id: 568768:Dpoa569_RS13155
uniprot id: A0A5B8IAM4
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

568768:Dpoa569 RS15550
gene id: 568768:Dpoa569_RS15550
uniprot id: A0A5B8I9Z4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS09530
gene id: 568768:Dpoa569_RS09530
uniprot id: A0A5B8HMF9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

568768:Dpoa569 RS13360
gene id: 568768:Dpoa569_RS13360
uniprot id: A0A5B8IAR3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

568768:Dpoa569 RS18230
gene id: 568768:Dpoa569_RS18230
uniprot id: A0A5B8HST1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

568768:Dpoa569 RS13760
gene id: 568768:Dpoa569_RS13760
uniprot id: A0A5B8I993
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

568768:Dpoa569 RS03070
gene id: 568768:Dpoa569_RS03070
uniprot id: A0A5B8I6R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

568768:Dpoa569 RS07445
gene id: 568768:Dpoa569_RS07445
uniprot id: A0A5B8HKH1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

568768:Dpoa569 RS00635
gene id: 568768:Dpoa569_RS00635
uniprot id: A0A5B8HYR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

568768:Dpoa569 RS02190
gene id: 568768:Dpoa569_RS02190
uniprot id: A0A5B8I662
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

568768:Dpoa569 RS04335
gene id: 568768:Dpoa569_RS04335
uniprot id: A0A5B8I353
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

568768:Dpoa569 RS02795
gene id: 568768:Dpoa569_RS02795
uniprot id: A0A5B8I245
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS03890
gene id: 568768:Dpoa569_RS03890
uniprot id: A0A5B8I793
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

568768:Dpoa569 RS07485
gene id: 568768:Dpoa569_RS07485
uniprot id: A0A5B8I531
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

568768:Dpoa569 RS03910
gene id: 568768:Dpoa569_RS03910
uniprot id: A0A5B8HIA5
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS07465
gene id: 568768:Dpoa569_RS07465
uniprot id: A0A5B8IBG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

568768:Dpoa569 RS17680
gene id: 568768:Dpoa569_RS17680
uniprot id: A0A5B8IBW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

568768:Dpoa569 RS19390
gene id: 568768:Dpoa569_RS19390
uniprot id: A0A5B8IEQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

568768:Dpoa569 RS14145
gene id: 568768:Dpoa569_RS14145
uniprot id: A0A5B8HQL7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

568768:Dpoa569 RS03525
gene id: 568768:Dpoa569_RS03525
uniprot id: A0A5B8HHY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS00105
gene id: 568768:Dpoa569_RS00105
uniprot id: A0A5Q2V4R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

568768:Dpoa569 RS16475
gene id: 568768:Dpoa569_RS16475
uniprot id: A0A5B8HQJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS05700
gene id: 568768:Dpoa569_RS05700
uniprot id: A0A5B8HHB6
names: Similarity
messages: Belongs to the GST superfamily.

568768:Dpoa569 RS08150
gene id: 568768:Dpoa569_RS08150
uniprot id: A0A5B8I5N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap.

568768:Dpoa569 RS10515
gene id: 568768:Dpoa569_RS10515
uniprot id: A0A5B8ID16
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

568768:Dpoa569 RS05765
gene id: 568768:Dpoa569_RS05765
uniprot id: A0A5B8I8P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

568768:Dpoa569 RS13480
gene id: 568768:Dpoa569_RS13480
uniprot id: A0A5B8I948
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS01660
gene id: 568768:Dpoa569_RS01660
uniprot id: A0A5B8HEF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Homotetramer.
messages: Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.

568768:Dpoa569 RS19370
gene id: 568768:Dpoa569_RS19370
uniprot id: A0A5B8ICD8
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

568768:Dpoa569 RS05810
gene id: 568768:Dpoa569_RS05810
uniprot id: A0A5B8HJ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

568768:Dpoa569 RS09575
gene id: 568768:Dpoa569_RS09575
uniprot id: A0A5B8I6K6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

568768:Dpoa569 RS10440
gene id: 568768:Dpoa569_RS10440
uniprot id: A0A5B8I920
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

568768:Dpoa569 RS00330
gene id: 568768:Dpoa569_RS00330
uniprot id: A0A5B8HDQ7
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
messages: Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.

568768:Dpoa569 RS11705
gene id: 568768:Dpoa569_RS11705
uniprot id: A0A5B8IEH0
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS16850
gene id: 568768:Dpoa569_RS16850
uniprot id: A0A5B8I9T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

568768:Dpoa569 RS05170
gene id: 568768:Dpoa569_RS05170
uniprot id: A0A5B8I266
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

568768:Dpoa569 RS07475
gene id: 568768:Dpoa569_RS07475
uniprot id: A0A5B8I3M9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

568768:Dpoa569 RS03020
gene id: 568768:Dpoa569_RS03020
uniprot id: A0A5B8I2J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

568768:Dpoa569 RS19125
gene id: 568768:Dpoa569_RS19125
uniprot id: A0A5B8HTA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS16495
gene id: 568768:Dpoa569_RS16495
uniprot id: A0A5B8HRV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

568768:Dpoa569 RS17240
gene id: 568768:Dpoa569_RS17240
uniprot id: A0A5B8IIY0
names: Similarity
messages: Belongs to the UPF0149 family.

568768:Dpoa569 RS19380
gene id: 568768:Dpoa569_RS19380
uniprot id: A0A5B8HUJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

568768:Dpoa569 RS08100
gene id: 568768:Dpoa569_RS08100
uniprot id: A0A5B8HL12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS13875
gene id: 568768:Dpoa569_RS13875
uniprot id: A0A5B8I9B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

568768:Dpoa569 RS03155
gene id: 568768:Dpoa569_RS03155
uniprot id: A0A5B8I2C9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
messages: Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM.

568768:Dpoa569 RS10635
gene id: 568768:Dpoa569_RS10635
uniprot id: A0A5B8HL73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

568768:Dpoa569 RS16640
gene id: 568768:Dpoa569_RS16640
uniprot id: A0A5B8HQM4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

568768:Dpoa569 RS05450
gene id: 568768:Dpoa569_RS05450
uniprot id: A0A5B8I418
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

568768:Dpoa569 RS08040
gene id: 568768:Dpoa569_RS08040
uniprot id: A0A5B8I5E6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

568768:Dpoa569 RS14965
gene id: 568768:Dpoa569_RS14965
uniprot id: A0A5B8HPN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS01615
gene id: 568768:Dpoa569_RS01615
uniprot id: A0A5B8I1B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.

568768:Dpoa569 RS01140
gene id: 568768:Dpoa569_RS01140
uniprot id: A0A5B8I0S1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

568768:Dpoa569 RS05650
gene id: 568768:Dpoa569_RS05650
uniprot id: A0A5B8HH66
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

568768:Dpoa569 RS05015
gene id: 568768:Dpoa569_RS05015
uniprot id: A0A5B8I232
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS00680
gene id: 568768:Dpoa569_RS00680
uniprot id: A0A5B8I5P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

568768:Dpoa569 RS02665
gene id: 568768:Dpoa569_RS02665
uniprot id: A0A5B8I6Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

568768:Dpoa569 RS01870
gene id: 568768:Dpoa569_RS01870
uniprot id: A0A5B8I5Z2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

568768:Dpoa569 RS18345
gene id: 568768:Dpoa569_RS18345
uniprot id: A0A5B8IJX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

568768:Dpoa569 RS07590
gene id: 568768:Dpoa569_RS07590
uniprot id: A0A5B8I5A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

568768:Dpoa569 RS02370
gene id: 568768:Dpoa569_RS02370
uniprot id: A0A5B8HGE6
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

568768:Dpoa569 RS16625
gene id: 568768:Dpoa569_RS16625
uniprot id: A0A5B8I9N1
names: Similarity
messages: Belongs to the peptidase S13 family.

568768:Dpoa569 RS04480
gene id: 568768:Dpoa569_RS04480
uniprot id: A0A5B8HGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

568768:Dpoa569 RS18890
gene id: 568768:Dpoa569_RS18890
uniprot id: A0A5B8HU80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS01375
gene id: 568768:Dpoa569_RS01375
uniprot id: A0A5B8I0Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

568768:Dpoa569 RS00150
gene id: 568768:Dpoa569_RS00150
uniprot id: A0A5B8HDL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

568768:Dpoa569 RS11960
gene id: 568768:Dpoa569_RS11960
uniprot id: A0A5B8I7W9
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS05665
gene id: 568768:Dpoa569_RS05665
uniprot id: A0A5B8I5Y6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS01675
gene id: 568768:Dpoa569_RS01675
uniprot id: A0A5B8HZH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

568768:Dpoa569 RS11865
gene id: 568768:Dpoa569_RS11865
uniprot id: A0A5B8HM92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS02095
gene id: 568768:Dpoa569_RS02095
uniprot id: A0A5B8I1L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

568768:Dpoa569 RS09125
gene id: 568768:Dpoa569_RS09125
uniprot id: A0A5B8I679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS08205
gene id: 568768:Dpoa569_RS08205
uniprot id: A0A5B8I5P8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

568768:Dpoa569 RS11730
gene id: 568768:Dpoa569_RS11730
uniprot id: A0A5B8I7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS01030
gene id: 568768:Dpoa569_RS01030
uniprot id: A0A5B8HZ15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
messages: Cell outer membrane
messages: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

568768:Dpoa569 RS05055
gene id: 568768:Dpoa569_RS05055
uniprot id: A0A5B8I8D5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

568768:Dpoa569 RS09900
gene id: 568768:Dpoa569_RS09900
uniprot id: A0A5B8I6L8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

568768:Dpoa569 RS11020
gene id: 568768:Dpoa569_RS11020
uniprot id: A0A5B8I5V4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

568768:Dpoa569 RS19095
gene id: 568768:Dpoa569_RS19095
uniprot id: A0A5B8ICY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS09175
gene id: 568768:Dpoa569_RS09175
uniprot id: A0A5B8I4M6
names: Similarity
messages: Belongs to the RutC family.

568768:Dpoa569 RS02110
gene id: 568768:Dpoa569_RS02110
uniprot id: A0A5B8I1Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

568768:Dpoa569 RS00315
gene id: 568768:Dpoa569_RS00315
uniprot id: A0A5B8HYF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

568768:Dpoa569 RS05060
gene id: 568768:Dpoa569_RS05060
uniprot id: A0A5B8I3S2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

568768:Dpoa569 RS03220
gene id: 568768:Dpoa569_RS03220
uniprot id: A0A5B8I2F3
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS07850
gene id: 568768:Dpoa569_RS07850
uniprot id: A0A5B8IBT8
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS18985
gene id: 568768:Dpoa569_RS18985
uniprot id: A0A5B8ICW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

568768:Dpoa569 RS08025
gene id: 568768:Dpoa569_RS08025
uniprot id: A0A5B8I5K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family. RNase II subfamily.
messages: Cytoplasm
messages: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.

568768:Dpoa569 RS10330
gene id: 568768:Dpoa569_RS10330
uniprot id: A0A5B8IBU3
names: Similarity
messages: Belongs to the UPF0434 family.

568768:Dpoa569 RS01880
gene id: 568768:Dpoa569_RS01880
uniprot id: A0A5B8HEJ3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

568768:Dpoa569 RS13035
gene id: 568768:Dpoa569_RS13035
uniprot id: A0A5B8HN55
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

568768:Dpoa569 RS00225
gene id: 568768:Dpoa569_RS00225
uniprot id: A0A5B8I059
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

568768:Dpoa569 RS09080
gene id: 568768:Dpoa569_RS09080
uniprot id: A0A5B8HJU8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

568768:Dpoa569 RS11340
gene id: 568768:Dpoa569_RS11340
uniprot id: A0A5B8HV41
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS08715
gene id: 568768:Dpoa569_RS08715
uniprot id: A0A5B8HLU7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

568768:Dpoa569 RS06755
gene id: 568768:Dpoa569_RS06755
uniprot id: A0A5B8I6G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

568768:Dpoa569 RS00815
gene id: 568768:Dpoa569_RS00815
uniprot id: A0A5B8HE24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

568768:Dpoa569 RS09360
gene id: 568768:Dpoa569_RS09360
uniprot id: A0A5B8IDP6
names: Similarity
messages: Belongs to the UPF0162 family.

568768:Dpoa569 RS10035
gene id: 568768:Dpoa569_RS10035
uniprot id: A0A5B8IDA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

568768:Dpoa569 RS07790
gene id: 568768:Dpoa569_RS07790
uniprot id: A0A5B8IBN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

568768:Dpoa569 RS14085
gene id: 568768:Dpoa569_RS14085
uniprot id: A0A5B8IEE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

568768:Dpoa569 RS17275
gene id: 568768:Dpoa569_RS17275
uniprot id: A0A5B8IIU6
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS06215
gene id: 568768:Dpoa569_RS06215
uniprot id: A0A5B8IAJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

568768:Dpoa569 RS16125
gene id: 568768:Dpoa569_RS16125
uniprot id: A0A5B8HRQ0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

568768:Dpoa569 RS01950
gene id: 568768:Dpoa569_RS01950
uniprot id: A0A5B8I6H5
names: Similarity
messages: Belongs to the UPF0270 family.

568768:Dpoa569 RS10420
gene id: 568768:Dpoa569_RS10420
uniprot id: A0A5B8I724
names: Subcellular Location Annotation
messages: Cytoplasm

568768:Dpoa569 RS18110
gene id: 568768:Dpoa569_RS18110
uniprot id: A0A5B8HRH0
names: Similarity
messages: Belongs to the glutamate synthase family.

568768:Dpoa569 RS18920
gene id: 568768:Dpoa569_RS18920
uniprot id: A0A5B8IB14
names: Similarity
messages: Belongs to the autoinducer synthase family.

568768:Dpoa569 RS18540
gene id: 568768:Dpoa569_RS18540
uniprot id: A0A5B8IK20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS01305
gene id: 568768:Dpoa569_RS01305
uniprot id: A0A5B8I0W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

568768:Dpoa569 RS01750
gene id: 568768:Dpoa569_RS01750
uniprot id: A0A5B8HEL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

568768:Dpoa569 RS01275
gene id: 568768:Dpoa569_RS01275
uniprot id: A0A5B8I0V0
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS14655
gene id: 568768:Dpoa569_RS14655
uniprot id: A0A5B8IGR4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

568768:Dpoa569 RS15045
gene id: 568768:Dpoa569_RS15045
uniprot id: A0A5B8I9Z5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

568768:Dpoa569 RS16650
gene id: 568768:Dpoa569_RS16650
uniprot id: A0A5B8IIB4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

568768:Dpoa569 RS12550
gene id: 568768:Dpoa569_RS12550
uniprot id: A0A5B8IDC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

568768:Dpoa569 RS16200
gene id: 568768:Dpoa569_RS16200
uniprot id: A0A5B8II19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

568768:Dpoa569 RS00255
gene id: 568768:Dpoa569_RS00255
uniprot id: A0A5B8I5E7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

568768:Dpoa569 RS01035
gene id: 568768:Dpoa569_RS01035
uniprot id: A0A5B8I0Q1
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

568768:Dpoa569 RS06055
gene id: 568768:Dpoa569_RS06055
uniprot id: A0A5B8I652
names: Similarity
messages: Belongs to the peptidase S66 family.

568768:Dpoa569 RS16430
gene id: 568768:Dpoa569_RS16430
uniprot id: A0A5B8HRT7
names: Similarity
messages: Belongs to the TPP enzyme family.

568768:Dpoa569 RS04905
gene id: 568768:Dpoa569_RS04905
uniprot id: A0A5B8I3I4
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

568768:Dpoa569 RS18905
gene id: 568768:Dpoa569_RS18905
uniprot id: A0A5B8HT61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS08930
gene id: 568768:Dpoa569_RS08930
uniprot id: A0A5B8HLX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

568768:Dpoa569 RS18520
gene id: 568768:Dpoa569_RS18520
uniprot id: A0A5B8HTY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
messages: Cytoplasm
messages: Monomer.

568768:Dpoa569 RS12575
gene id: 568768:Dpoa569_RS12575
uniprot id: A0A5B8I6U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

568768:Dpoa569 RS05040
gene id: 568768:Dpoa569_RS05040
uniprot id: A0A5B8I820
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS04775
gene id: 568768:Dpoa569_RS04775
uniprot id: A0A5B8I3K3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

568768:Dpoa569 RS10575
gene id: 568768:Dpoa569_RS10575
uniprot id: A0A5B8I757
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

568768:Dpoa569 RS04935
gene id: 568768:Dpoa569_RS04935
uniprot id: A0A5B8I8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

568768:Dpoa569 RS05730
gene id: 568768:Dpoa569_RS05730
uniprot id: A0A5B8I480
names: Similarity
messages: Belongs to the UPF0304 family.

568768:Dpoa569 RS10460
gene id: 568768:Dpoa569_RS10460
uniprot id: A0A5B8I5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

568768:Dpoa569 RS19285
gene id: 568768:Dpoa569_RS19285
uniprot id: A0A5B8IEN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

568768:Dpoa569 RS10465
gene id: 568768:Dpoa569_RS10465
uniprot id: A0A5B8I796
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

568768:Dpoa569 RS07205
gene id: 568768:Dpoa569_RS07205
uniprot id: A0A5B8I4X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

568768:Dpoa569 RS01115
gene id: 568768:Dpoa569_RS01115
uniprot id: A0A5B8I0R7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

568768:Dpoa569 RS07885
gene id: 568768:Dpoa569_RS07885
uniprot id: A0A5B8HIZ2
names: Similarity
messages: Belongs to the CFA/CMAS family.

568768:Dpoa569 RS18245
gene id: 568768:Dpoa569_RS18245
uniprot id: A0A5B8IAP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

568768:Dpoa569 RS02520
gene id: 568768:Dpoa569_RS02520
uniprot id: A0A5B8I044
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

568768:Dpoa569 RS07110
gene id: 568768:Dpoa569_RS07110
uniprot id: A0A5B8HID9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

568768:Dpoa569 RS17985
gene id: 568768:Dpoa569_RS17985
uniprot id: A0A5B8IAI8
names: Subunit
messages: Monomer.

568768:Dpoa569 RS12450
gene id: 568768:Dpoa569_RS12450
uniprot id: A0A5B8I871
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

568768:Dpoa569 RS07005
gene id: 568768:Dpoa569_RS07005
uniprot id: A0A5B8I9J6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.
messages: Electron-transport protein of unknown function.

568768:Dpoa569 RS06065
gene id: 568768:Dpoa569_RS06065
uniprot id: A0A5B8IAG2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

568768:Dpoa569 RS09355
gene id: 568768:Dpoa569_RS09355
uniprot id: A0A5B8I6A5
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

568768:Dpoa569 RS06170
gene id: 568768:Dpoa569_RS06170
uniprot id: A0A5B8I4G5
names: Similarity
messages: Belongs to the MobA/MobL family.

568768:Dpoa569 RS04555
gene id: 568768:Dpoa569_RS04555
uniprot id: A0A5B8HIR4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

568768:Dpoa569 RS07335
gene id: 568768:Dpoa569_RS07335
uniprot id: A0A5B8HKA1
names: Similarity
messages: Belongs to the peptidase S16 family.

568768:Dpoa569 RS15380
gene id: 568768:Dpoa569_RS15380
uniprot id: A0A5B8I9W5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

568768:Dpoa569 RS12005
gene id: 568768:Dpoa569_RS12005
uniprot id: A0A5B8I6G8
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

568768:Dpoa569 RS03320
gene id: 568768:Dpoa569_RS03320
uniprot id: A0A5B8I2H6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

568768:Dpoa569 RS10450
gene id: 568768:Dpoa569_RS10450
uniprot id: A0A5B8IDN6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

568768:Dpoa569 RS07820
gene id: 568768:Dpoa569_RS07820
uniprot id: A0A5B8I597
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
messages: Cytoplasm
messages: Homodimer. Interacts with SufE and the SufBCD complex composed of SufB, SufC and SufD. The interaction with SufE is required to mediate the direct transfer of the sulfur atom from the S-sulfanylcysteine.

568768:Dpoa569 RS03440
gene id: 568768:Dpoa569_RS03440
uniprot id: A0A5B8I2K3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS15740
gene id: 568768:Dpoa569_RS15740
uniprot id: A0A5B8IHP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

568768:Dpoa569 RS13425
gene id: 568768:Dpoa569_RS13425
uniprot id: A0A5B8I936
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

568768:Dpoa569 RS11055
gene id: 568768:Dpoa569_RS11055
uniprot id: A0A5B8HNL9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS09010
gene id: 568768:Dpoa569_RS09010
uniprot id: A0A5B8I632
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

568768:Dpoa569 RS07780
gene id: 568768:Dpoa569_RS07780
uniprot id: A0A5B8I750
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

568768:Dpoa569 RS15400
gene id: 568768:Dpoa569_RS15400
uniprot id: A0A5B8IC45
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS15590
gene id: 568768:Dpoa569_RS15590
uniprot id: A0A5B8I8X1
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

568768:Dpoa569 RS09315
gene id: 568768:Dpoa569_RS09315
uniprot id: A0A5B8HMA1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

568768:Dpoa569 RS01390
gene id: 568768:Dpoa569_RS01390
uniprot id: A0A5B8I157
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

568768:Dpoa569 RS10665
gene id: 568768:Dpoa569_RS10665
uniprot id: A0A5B8IDS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS04670
gene id: 568768:Dpoa569_RS04670
uniprot id: A0A5B8I863
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

568768:Dpoa569 RS18750
gene id: 568768:Dpoa569_RS18750
uniprot id: A0A5B8IK93
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

568768:Dpoa569 RS11965
gene id: 568768:Dpoa569_RS11965
uniprot id: A0A5B8HMC4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS00055
gene id: 568768:Dpoa569_RS00055
uniprot id: A0A5B8HTI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

568768:Dpoa569 RS18800
gene id: 568768:Dpoa569_RS18800
uniprot id: A0A5B8HT41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS00985
gene id: 568768:Dpoa569_RS00985
uniprot id: A0A5B8HE54
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

568768:Dpoa569 RS15050
gene id: 568768:Dpoa569_RS15050
uniprot id: A0A5B8I8K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS13515
gene id: 568768:Dpoa569_RS13515
uniprot id: A0A5B8IAY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

568768:Dpoa569 RS11875
gene id: 568768:Dpoa569_RS11875
uniprot id: A0A5B8ICX4
names: Similarity
messages: Belongs to the HupF/HypC family.

568768:Dpoa569 RS17945
gene id: 568768:Dpoa569_RS17945
uniprot id: A0A5B8HRD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose mutarotase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the anomeric conversion of L-rhamnose.

568768:Dpoa569 RS11635
gene id: 568768:Dpoa569_RS11635
uniprot id: A0A5B8I9Q6
names: Similarity
messages: Belongs to the PrpF family.

568768:Dpoa569 RS03245
gene id: 568768:Dpoa569_RS03245
uniprot id: A0A5B8I2Q2
names: Similarity
messages: Belongs to the PrpD family.

568768:Dpoa569 RS02765
gene id: 568768:Dpoa569_RS02765
uniprot id: A0A5B8HGN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

568768:Dpoa569 RS10340
gene id: 568768:Dpoa569_RS10340
uniprot id: A0A5B8HN37
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS03285
gene id: 568768:Dpoa569_RS03285
uniprot id: A0A5B8HH73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

568768:Dpoa569 RS05350
gene id: 568768:Dpoa569_RS05350
uniprot id: A0A5B8IL82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

568768:Dpoa569 RS03290
gene id: 568768:Dpoa569_RS03290
uniprot id: A0A5B8I6W2
names: Similarity
messages: Belongs to the DapA family.

568768:Dpoa569 RS18075
gene id: 568768:Dpoa569_RS18075
uniprot id: A0A5B8IDT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

568768:Dpoa569 RS00390
gene id: 568768:Dpoa569_RS00390
uniprot id: A0A5B8HDS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

568768:Dpoa569 RS07680
gene id: 568768:Dpoa569_RS07680
uniprot id: A0A5B8IBL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

568768:Dpoa569 RS16390
gene id: 568768:Dpoa569_RS16390
uniprot id: A0A5B8IAQ1
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

568768:Dpoa569 RS11410
gene id: 568768:Dpoa569_RS11410
uniprot id: A0A5B8I7K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtfA family.
messages: Cytoplasm
messages: Interacts with Mlc.
messages: Involved in the regulation of ptsG expression by binding and inactivating Mlc.

568768:Dpoa569 RS12915
gene id: 568768:Dpoa569_RS12915
uniprot id: A0A5B8I718
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

568768:Dpoa569 RS03995
gene id: 568768:Dpoa569_RS03995
uniprot id: A0A5B8HHS5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

568768:Dpoa569 RS05305
gene id: 568768:Dpoa569_RS05305
uniprot id: A0A5B8I8E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

568768:Dpoa569 RS11535
gene id: 568768:Dpoa569_RS11535
uniprot id: A0A5B8I9N5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

568768:Dpoa569 RS04795
gene id: 568768:Dpoa569_RS04795
uniprot id: A0A5B8HGM9
names: Similarity
messages: Belongs to the peptidase S66 family.

568768:Dpoa569 RS13275
gene id: 568768:Dpoa569_RS13275
uniprot id: A0A5B8I799
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

568768:Dpoa569 RS15755
gene id: 568768:Dpoa569_RS15755
uniprot id: A0A5B8IAQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

568768:Dpoa569 RS00050
gene id: 568768:Dpoa569_RS00050
uniprot id: A0A5B8IER9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS19015
gene id: 568768:Dpoa569_RS19015
uniprot id: A0A5B8HT77
names: Similarity
messages: Belongs to the FrmR/RcnR family.

568768:Dpoa569 RS05635
gene id: 568768:Dpoa569_RS05635
uniprot id: A0A5B8I452
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS05545
gene id: 568768:Dpoa569_RS05545
uniprot id: A0A5B8I8J3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

568768:Dpoa569 RS12855
gene id: 568768:Dpoa569_RS12855
uniprot id: A0A5B8IFC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS17355
gene id: 568768:Dpoa569_RS17355
uniprot id: A0A5B8IJ12
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

568768:Dpoa569 RS06075
gene id: 568768:Dpoa569_RS06075
uniprot id: A0A5B8I2R3
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS09625
gene id: 568768:Dpoa569_RS09625
uniprot id: A0A5B8ICZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

568768:Dpoa569 RS08065
gene id: 568768:Dpoa569_RS08065
uniprot id: A0A5B8HL40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS07240
gene id: 568768:Dpoa569_RS07240
uniprot id: A0A5B8IBB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

568768:Dpoa569 RS05585
gene id: 568768:Dpoa569_RS05585
uniprot id: A0A5B8HH51
names: Similarity
messages: Belongs to the GST superfamily.

568768:Dpoa569 RS04770
gene id: 568768:Dpoa569_RS04770
uniprot id: A0A5B8I886
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

568768:Dpoa569 RS09940
gene id: 568768:Dpoa569_RS09940
uniprot id: A0A5B8I6N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

568768:Dpoa569 RS10730
gene id: 568768:Dpoa569_RS10730
uniprot id: A0A5B8I5P6
names: Similarity
messages: Belongs to the GST superfamily.

568768:Dpoa569 RS04495
gene id: 568768:Dpoa569_RS04495
uniprot id: A0A5B8I550
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

568768:Dpoa569 RS07130
gene id: 568768:Dpoa569_RS07130
uniprot id: A0A5B8HKF9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

568768:Dpoa569 RS02910
gene id: 568768:Dpoa569_RS02910
uniprot id: A0A5B8I6N0
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

568768:Dpoa569 RS07095
gene id: 568768:Dpoa569_RS07095
uniprot id: A0A5B8I3E5
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

568768:Dpoa569 RS12995
gene id: 568768:Dpoa569_RS12995
uniprot id: A0A5B8IDN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

568768:Dpoa569 RS04055
gene id: 568768:Dpoa569_RS04055
uniprot id: A0A5B8I3B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

568768:Dpoa569 RS18170
gene id: 568768:Dpoa569_RS18170
uniprot id: A0A5B8IJM2
names: Similarity
messages: Belongs to the BolA/IbaG family.

568768:Dpoa569 RS12635
gene id: 568768:Dpoa569_RS12635
uniprot id: A0A5B8I8A7
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

568768:Dpoa569 RS08495
gene id: 568768:Dpoa569_RS08495
uniprot id: A0A5B8I7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

568768:Dpoa569 RS02335
gene id: 568768:Dpoa569_RS02335
uniprot id: A0A5B8IEU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

568768:Dpoa569 RS09020
gene id: 568768:Dpoa569_RS09020
uniprot id: A0A5B8I650
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

568768:Dpoa569 RS18000
gene id: 568768:Dpoa569_RS18000
uniprot id: A0A5B8HRE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

568768:Dpoa569 RS00950
gene id: 568768:Dpoa569_RS00950
uniprot id: A0A5B8HE09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

568768:Dpoa569 RS07540
gene id: 568768:Dpoa569_RS07540
uniprot id: A0A5B8I544
names: Similarity
messages: Belongs to the UPF0227 family.

568768:Dpoa569 RS13120
gene id: 568768:Dpoa569_RS13120
uniprot id: A0A5B8I773
names: Similarity
messages: Belongs to the CinA family.

568768:Dpoa569 RS17990
gene id: 568768:Dpoa569_RS17990
uniprot id: A0A5B8IC75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

568768:Dpoa569 RS07670
gene id: 568768:Dpoa569_RS07670
uniprot id: A0A5B8I723
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

568768:Dpoa569 RS18480
gene id: 568768:Dpoa569_RS18480
uniprot id: A0A5B8HSX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

568768:Dpoa569 RS03655
gene id: 568768:Dpoa569_RS03655
uniprot id: A0A5B8I0Z1
names: Similarity
messages: Belongs to the CdaR family.

568768:Dpoa569 RS14135
gene id: 568768:Dpoa569_RS14135
uniprot id: A0A5B8IEF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

568768:Dpoa569 RS10950
gene id: 568768:Dpoa569_RS10950
uniprot id: A0A5B8I7E3
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS01125
gene id: 568768:Dpoa569_RS01125
uniprot id: A0A5B8HE75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

568768:Dpoa569 RS00415
gene id: 568768:Dpoa569_RS00415
uniprot id: A0A5B8ICY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS04895
gene id: 568768:Dpoa569_RS04895
uniprot id: A0A5B8I206
names: Subcellular Location Annotation
messages: Cell inner membrane

568768:Dpoa569 RS13925
gene id: 568768:Dpoa569_RS13925
uniprot id: A0A5B8I9C5
names: Similarity
messages: Belongs to the UPF0325 family.

568768:Dpoa569 RS03600
gene id: 568768:Dpoa569_RS03600
uniprot id: A0A5B8I2N3
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

568768:Dpoa569 RS04255
gene id: 568768:Dpoa569_RS04255
uniprot id: A0A5B8I4Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS18360
gene id: 568768:Dpoa569_RS18360
uniprot id: A0A5B8ICG8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

568768:Dpoa569 RS07435
gene id: 568768:Dpoa569_RS07435
uniprot id: A0A5B8I520
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

568768:Dpoa569 RS01990
gene id: 568768:Dpoa569_RS01990
uniprot id: A0A5B8I1E2
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS04580
gene id: 568768:Dpoa569_RS04580
uniprot id: A0A5B8I3G9
names: Similarity
messages: Belongs to the P(II) protein family.

568768:Dpoa569 RS05140
gene id: 568768:Dpoa569_RS05140
uniprot id: A0A5B8I846
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS04035
gene id: 568768:Dpoa569_RS04035
uniprot id: A0A5B8I2Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS13170
gene id: 568768:Dpoa569_RS13170
uniprot id: A0A5B8I8Y0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

568768:Dpoa569 RS07340
gene id: 568768:Dpoa569_RS07340
uniprot id: A0A5B8I9R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

568768:Dpoa569 RS01580
gene id: 568768:Dpoa569_RS01580
uniprot id: A0A5B8I139
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

568768:Dpoa569 RS03465
gene id: 568768:Dpoa569_RS03465
uniprot id: A0A5B8I2V3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

568768:Dpoa569 RS11505
gene id: 568768:Dpoa569_RS11505
uniprot id: A0A5B8I675
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS14860
gene id: 568768:Dpoa569_RS14860
uniprot id: A0A5B8I9L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

568768:Dpoa569 RS11045
gene id: 568768:Dpoa569_RS11045
uniprot id: A0A5B8ICB0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

568768:Dpoa569 RS09070
gene id: 568768:Dpoa569_RS09070
uniprot id: A0A5B8I666
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS13175
gene id: 568768:Dpoa569_RS13175
uniprot id: A0A5B8I781
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.
messages: Belongs to the RcsC family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
messages: Interacts with RcsD.

568768:Dpoa569 RS10300
gene id: 568768:Dpoa569_RS10300
uniprot id: A0A5B8I6W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

568768:Dpoa569 RS09680
gene id: 568768:Dpoa569_RS09680
uniprot id: A0A5B8ID14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

568768:Dpoa569 RS07985
gene id: 568768:Dpoa569_RS07985
uniprot id: A0A5B8I5D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

568768:Dpoa569 RS10100
gene id: 568768:Dpoa569_RS10100
uniprot id: A0A5B8I719
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Periplasm

568768:Dpoa569 RS15060
gene id: 568768:Dpoa569_RS15060
uniprot id: A0A5B8I9R0
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS16685
gene id: 568768:Dpoa569_RS16685
uniprot id: A0A5B8I9P4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

568768:Dpoa569 RS15205
gene id: 568768:Dpoa569_RS15205
uniprot id: A0A5B8I9T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

568768:Dpoa569 RS18340
gene id: 568768:Dpoa569_RS18340
uniprot id: A0A5B8HSV2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

568768:Dpoa569 RS12360
gene id: 568768:Dpoa569_RS12360
uniprot id: A0A5B8HPQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

568768:Dpoa569 RS13920
gene id: 568768:Dpoa569_RS13920
uniprot id: A0A5B8IG94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

568768:Dpoa569 RS00075
gene id: 568768:Dpoa569_RS00075
uniprot id: A0A5B8ID72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

568768:Dpoa569 RS11060
gene id: 568768:Dpoa569_RS11060
uniprot id: A0A5B8IE29
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS15745
gene id: 568768:Dpoa569_RS15745
uniprot id: A0A5B8IAC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS00100
gene id: 568768:Dpoa569_RS00100
uniprot id: A0A5B8IET0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

568768:Dpoa569 RS00865
gene id: 568768:Dpoa569_RS00865
uniprot id: A0A5B8I0L3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

568768:Dpoa569 RS15645
gene id: 568768:Dpoa569_RS15645
uniprot id: A0A5B8IAN4
names: Subcellular Location Annotation
messages: Cytoplasm

568768:Dpoa569 RS16690
gene id: 568768:Dpoa569_RS16690
uniprot id: A0A5B8IBB3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

568768:Dpoa569 RS12395
gene id: 568768:Dpoa569_RS12395
uniprot id: A0A5B8I8L6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

568768:Dpoa569 RS03190
gene id: 568768:Dpoa569_RS03190
uniprot id: A0A5B8HUP7
names: Similarity
messages: Belongs to the GSP E family.

568768:Dpoa569 RS07190
gene id: 568768:Dpoa569_RS07190
uniprot id: A0A5B8I519
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

568768:Dpoa569 RS03125
gene id: 568768:Dpoa569_RS03125
uniprot id: A0A5B8I2M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

568768:Dpoa569 RS02080
gene id: 568768:Dpoa569_RS02080
uniprot id: A0A5B8HEU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

568768:Dpoa569 RS13240
gene id: 568768:Dpoa569_RS13240
uniprot id: A0A5B8HNC6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

568768:Dpoa569 RS13560
gene id: 568768:Dpoa569_RS13560
uniprot id: A0A5B8IE35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

568768:Dpoa569 RS15485
gene id: 568768:Dpoa569_RS15485
uniprot id: A0A5B8IA79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

568768:Dpoa569 RS09600
gene id: 568768:Dpoa569_RS09600
uniprot id: A0A5B8IF83
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS07710
gene id: 568768:Dpoa569_RS07710
uniprot id: A0A5B8HIU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS17700
gene id: 568768:Dpoa569_RS17700
uniprot id: A0A5B8IJ61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

568768:Dpoa569 RS07570
gene id: 568768:Dpoa569_RS07570
uniprot id: A0A5B8IBI4
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

568768:Dpoa569 RS12270
gene id: 568768:Dpoa569_RS12270
uniprot id: A0A5B8IA33
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

568768:Dpoa569 RS19065
gene id: 568768:Dpoa569_RS19065
uniprot id: A0A5B8HT91
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS12650
gene id: 568768:Dpoa569_RS12650
uniprot id: A0A5B8IDE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

568768:Dpoa569 RS12105
gene id: 568768:Dpoa569_RS12105
uniprot id: A0A5B8I9Z9
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS07650
gene id: 568768:Dpoa569_RS07650
uniprot id: A0A5B8HTY8
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

568768:Dpoa569 RS10350
gene id: 568768:Dpoa569_RS10350
uniprot id: A0A5B8I726
names: Similarity
messages: Belongs to the UPF0265 family.

568768:Dpoa569 RS02010
gene id: 568768:Dpoa569_RS02010
uniprot id: A0A5B8HZR9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

568768:Dpoa569 RS02375
gene id: 568768:Dpoa569_RS02375
uniprot id: A0A5B8I6A0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

568768:Dpoa569 RS19310
gene id: 568768:Dpoa569_RS19310
uniprot id: A0A5B8ID39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS14855
gene id: 568768:Dpoa569_RS14855
uniprot id: A0A5B8HT23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

568768:Dpoa569 RS04275
gene id: 568768:Dpoa569_RS04275
uniprot id: A0A5B8I1G4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

568768:Dpoa569 RS03990
gene id: 568768:Dpoa569_RS03990
uniprot id: A0A5B8HG66
names: Subcellular Location Annotation
messages: Cell inner membrane

568768:Dpoa569 RS08980
gene id: 568768:Dpoa569_RS08980
uniprot id: A0A5B8HLZ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS16190
gene id: 568768:Dpoa569_RS16190
uniprot id: A0A5B8ICP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

568768:Dpoa569 RS02990
gene id: 568768:Dpoa569_RS02990
uniprot id: A0A5B8I2A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

568768:Dpoa569 RS08090
gene id: 568768:Dpoa569_RS08090
uniprot id: A0A5B8I5F8
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS19350
gene id: 568768:Dpoa569_RS19350
uniprot id: A0A5B8IKT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS05925
gene id: 568768:Dpoa569_RS05925
uniprot id: A0A5B8I8W3
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

568768:Dpoa569 RS06870
gene id: 568768:Dpoa569_RS06870
uniprot id: A0A5B8HI64
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

568768:Dpoa569 RS09610
gene id: 568768:Dpoa569_RS09610
uniprot id: A0A5B8I898
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

568768:Dpoa569 RS11640
gene id: 568768:Dpoa569_RS11640
uniprot id: A0A5B8HP24
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS04045
gene id: 568768:Dpoa569_RS04045
uniprot id: A0A5B8HHU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS09540
gene id: 568768:Dpoa569_RS09540
uniprot id: A0A5B8HSU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

568768:Dpoa569 RS08275
gene id: 568768:Dpoa569_RS08275
uniprot id: A0A5B8HJA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS04660
gene id: 568768:Dpoa569_RS04660
uniprot id: A0A5B8I5C4
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

568768:Dpoa569 RS17215
gene id: 568768:Dpoa569_RS17215
uniprot id: A0A5B8HT29
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

568768:Dpoa569 RS01805
gene id: 568768:Dpoa569_RS01805
uniprot id: A0A5B8HG05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

568768:Dpoa569 RS17250
gene id: 568768:Dpoa569_RS17250
uniprot id: A0A5B8IA46
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

568768:Dpoa569 RS08280
gene id: 568768:Dpoa569_RS08280
uniprot id: A0A5B8HL47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS02945
gene id: 568768:Dpoa569_RS02945
uniprot id: A0A5B8I279
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

568768:Dpoa569 RS14870
gene id: 568768:Dpoa569_RS14870
uniprot id: A0A5B8HRL3
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

568768:Dpoa569 RS01480
gene id: 568768:Dpoa569_RS01480
uniprot id: A0A5B8HEE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS18050
gene id: 568768:Dpoa569_RS18050
uniprot id: A0A5B8IBG5
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

568768:Dpoa569 RS17725
gene id: 568768:Dpoa569_RS17725
uniprot id: A0A5B8IAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

568768:Dpoa569 RS02145
gene id: 568768:Dpoa569_RS02145
uniprot id: A0A5B8I1S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

568768:Dpoa569 RS07025
gene id: 568768:Dpoa569_RS07025
uniprot id: A0A5B8IEU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

568768:Dpoa569 RS13870
gene id: 568768:Dpoa569_RS13870
uniprot id: A0A5B8IG84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

568768:Dpoa569 RS15815
gene id: 568768:Dpoa569_RS15815
uniprot id: A0A5B8IAR4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

568768:Dpoa569 RS03080
gene id: 568768:Dpoa569_RS03080
uniprot id: A0A5B8HHK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

568768:Dpoa569 RS02595
gene id: 568768:Dpoa569_RS02595
uniprot id: A0A5B8I6E7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

568768:Dpoa569 RS05990
gene id: 568768:Dpoa569_RS05990
uniprot id: A0A5B8I639
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

568768:Dpoa569 RS18320
gene id: 568768:Dpoa569_RS18320
uniprot id: A0A5B8HRL0
names: Similarity
messages: Belongs to the MreC family.

568768:Dpoa569 RS01455
gene id: 568768:Dpoa569_RS01455
uniprot id: A0A5B8I647
names: Cofactor
messages: Binds 1 zinc ion per subunit.

568768:Dpoa569 RS19335
gene id: 568768:Dpoa569_RS19335
uniprot id: A0A5B8IKQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell membrane

568768:Dpoa569 RS04350
gene id: 568768:Dpoa569_RS04350
uniprot id: A0A5B8I7M1
names: Similarity
messages: Belongs to the CdaR family.

568768:Dpoa569 RS07470
gene id: 568768:Dpoa569_RS07470
uniprot id: A0A5B8I573
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

568768:Dpoa569 RS10840
gene id: 568768:Dpoa569_RS10840
uniprot id: A0A5B8HNG1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

568768:Dpoa569 RS10325
gene id: 568768:Dpoa569_RS10325
uniprot id: A0A5B8HN40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

568768:Dpoa569 RS03485
gene id: 568768:Dpoa569_RS03485
uniprot id: A0A5B8I0U9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

568768:Dpoa569 RS08565
gene id: 568768:Dpoa569_RS08565
uniprot id: A0A5B8I4C8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

568768:Dpoa569 RS10980
gene id: 568768:Dpoa569_RS10980
uniprot id: A0A5B8HNL5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

568768:Dpoa569 RS13460
gene id: 568768:Dpoa569_RS13460
uniprot id: A0A5B8IAW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

568768:Dpoa569 RS07020
gene id: 568768:Dpoa569_RS07020
uniprot id: A0A5B8HKD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

568768:Dpoa569 RS14070
gene id: 568768:Dpoa569_RS14070
uniprot id: A0A5B8ID71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

568768:Dpoa569 RS07430
gene id: 568768:Dpoa569_RS07430
uniprot id: A0A5B8I570
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

568768:Dpoa569 RS17195
gene id: 568768:Dpoa569_RS17195
uniprot id: A0A5B8IA31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

568768:Dpoa569 RS02710
gene id: 568768:Dpoa569_RS02710
uniprot id: A0A5B8HGM2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

568768:Dpoa569 RS16645
gene id: 568768:Dpoa569_RS16645
uniprot id: A0A5B8HSQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

568768:Dpoa569 RS01665
gene id: 568768:Dpoa569_RS01665
uniprot id: A0A5B8I691
names: Subcellular Location Annotation
messages: Cytoplasm

568768:Dpoa569 RS03930
gene id: 568768:Dpoa569_RS03930
uniprot id: A0A5B8I311
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS01915
gene id: 568768:Dpoa569_RS01915
uniprot id: A0A5B8HEQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

568768:Dpoa569 RS00990
gene id: 568768:Dpoa569_RS00990
uniprot id: A0A5B8HFC4
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

568768:Dpoa569 RS01475
gene id: 568768:Dpoa569_RS01475
uniprot id: A0A5B8I108
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

568768:Dpoa569 RS05680
gene id: 568768:Dpoa569_RS05680
uniprot id: A0A5B8I468
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

568768:Dpoa569 RS12755
gene id: 568768:Dpoa569_RS12755
uniprot id: A0A5B8IAD0
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS07440
gene id: 568768:Dpoa569_RS07440
uniprot id: A0A5B8HIM2
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

568768:Dpoa569 RS05380
gene id: 568768:Dpoa569_RS05380
uniprot id: A0A5B8I8L1
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

568768:Dpoa569 RS05460
gene id: 568768:Dpoa569_RS05460
uniprot id: A0A5B8I3W4
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS00460
gene id: 568768:Dpoa569_RS00460
uniprot id: A0A5B8I0C0
names: Similarity
messages: Belongs to the FGGY kinase family.

568768:Dpoa569 RS14915
gene id: 568768:Dpoa569_RS14915
uniprot id: A0A5B8HPL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

568768:Dpoa569 RS11255
gene id: 568768:Dpoa569_RS11255
uniprot id: A0A5B8ICH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS17855
gene id: 568768:Dpoa569_RS17855
uniprot id: A0A5B8IJC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

568768:Dpoa569 RS05555
gene id: 568768:Dpoa569_RS05555
uniprot id: A0A5B8HJI0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M74 family.
messages: Binds 2 Zn(2+) ions per subunit. Zn(2+) ion 1 is bound in the active site. Zn(2+) ion 2 is bound at the dimer interface by residues from both subunits.
messages: Dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.
messages: Periplasm

568768:Dpoa569 RS10235
gene id: 568768:Dpoa569_RS10235
uniprot id: A0A5B8IDI6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.
messages: Homotrimer.

568768:Dpoa569 RS11085
gene id: 568768:Dpoa569_RS11085
uniprot id: A0A5B8HLK8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

568768:Dpoa569 RS15160
gene id: 568768:Dpoa569_RS15160
uniprot id: A0A5B8HRT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

568768:Dpoa569 RS07715
gene id: 568768:Dpoa569_RS07715
uniprot id: A0A5B8HKQ9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.
messages: FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.
messages: Homotetramer.

568768:Dpoa569 RS01265
gene id: 568768:Dpoa569_RS01265
uniprot id: A0A5B8HFI4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

568768:Dpoa569 RS09875
gene id: 568768:Dpoa569_RS09875
uniprot id: A0A5B8I8F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS16005
gene id: 568768:Dpoa569_RS16005
uniprot id: A0A5B8ICK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0257 family.
messages: Cell membrane

568768:Dpoa569 RS02125
gene id: 568768:Dpoa569_RS02125
uniprot id: A0A5B8I1N1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

568768:Dpoa569 RS12810
gene id: 568768:Dpoa569_RS12810
uniprot id: A0A5B8I8Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS10885
gene id: 568768:Dpoa569_RS10885
uniprot id: A0A5B8IC70
names: Similarity
messages: Belongs to the peptidase C40 family.

568768:Dpoa569 RS12605
gene id: 568768:Dpoa569_RS12605
uniprot id: A0A5B8IAA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

568768:Dpoa569 RS03185
gene id: 568768:Dpoa569_RS03185
uniprot id: A0A5B8HHN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS10175
gene id: 568768:Dpoa569_RS10175
uniprot id: A0A5B8I8R6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

568768:Dpoa569 RS04125
gene id: 568768:Dpoa569_RS04125
uniprot id: A0A5B8I7U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

568768:Dpoa569 RS14055
gene id: 568768:Dpoa569_RS14055
uniprot id: A0A5B8I9Q5
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS04340
gene id: 568768:Dpoa569_RS04340
uniprot id: A0A5B8HGD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

568768:Dpoa569 RS02360
gene id: 568768:Dpoa569_RS02360
uniprot id: A0A5B8I1T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

568768:Dpoa569 RS04040
gene id: 568768:Dpoa569_RS04040
uniprot id: A0A5B8HG81
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

568768:Dpoa569 RS03900
gene id: 568768:Dpoa569_RS03900
uniprot id: A0A5B8IEX3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS11450
gene id: 568768:Dpoa569_RS11450
uniprot id: A0A5B8I7M6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

568768:Dpoa569 RS01500
gene id: 568768:Dpoa569_RS01500
uniprot id: A0A5B8I113
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

568768:Dpoa569 RS05575
gene id: 568768:Dpoa569_RS05575
uniprot id: A0A5B8I442
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

568768:Dpoa569 RS01875
gene id: 568768:Dpoa569_RS01875
uniprot id: A0A5B8I1B5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

568768:Dpoa569 RS04110
gene id: 568768:Dpoa569_RS04110
uniprot id: A0A5B8I7F2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS10815
gene id: 568768:Dpoa569_RS10815
uniprot id: A0A5B8HLC3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS15910
gene id: 568768:Dpoa569_RS15910
uniprot id: A0A5B8HRJ9
names: Similarity
messages: Belongs to the GSP E family.

568768:Dpoa569 RS09245
gene id: 568768:Dpoa569_RS09245
uniprot id: A0A5B8I659
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

568768:Dpoa569 RS04490
gene id: 568768:Dpoa569_RS04490
uniprot id: A0A5B8I7P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

568768:Dpoa569 RS15720
gene id: 568768:Dpoa569_RS15720
uniprot id: A0A5B8HS51
names: Similarity
messages: Belongs to the UPF0178 family.

568768:Dpoa569 RS03860
gene id: 568768:Dpoa569_RS03860
uniprot id: A0A5B8I156
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS08270
gene id: 568768:Dpoa569_RS08270
uniprot id: A0A5B8I5J6
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

568768:Dpoa569 RS08610
gene id: 568768:Dpoa569_RS08610
uniprot id: A0A5B8I5Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

568768:Dpoa569 RS00010
gene id: 568768:Dpoa569_RS00010
uniprot id: A0A5B8ICW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

568768:Dpoa569 RS17320
gene id: 568768:Dpoa569_RS17320
uniprot id: A0A5B8HT53
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS05815
gene id: 568768:Dpoa569_RS05815
uniprot id: A0A5B8I8Q2
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS18125
gene id: 568768:Dpoa569_RS18125
uniprot id: A0A5B8IDV1
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

568768:Dpoa569 RS05715
gene id: 568768:Dpoa569_RS05715
uniprot id: A0A5B8I5Z4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

568768:Dpoa569 RS06050
gene id: 568768:Dpoa569_RS06050
uniprot id: A0A5B8I8Y6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

568768:Dpoa569 RS10900
gene id: 568768:Dpoa569_RS10900
uniprot id: A0A5B8IDY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

568768:Dpoa569 RS03095
gene id: 568768:Dpoa569_RS03095
uniprot id: A0A5B8I0J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

568768:Dpoa569 RS13880
gene id: 568768:Dpoa569_RS13880
uniprot id: A0A5B8IF81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

568768:Dpoa569 RS18255
gene id: 568768:Dpoa569_RS18255
uniprot id: A0A5B8IBM4
names: Similarity
messages: Belongs to the peptidase U62 family.

568768:Dpoa569 RS04210
gene id: 568768:Dpoa569_RS04210
uniprot id: A0A5B8I7W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

568768:Dpoa569 RS02155
gene id: 568768:Dpoa569_RS02155
uniprot id: A0A5B8I6M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

568768:Dpoa569 RS02420
gene id: 568768:Dpoa569_RS02420
uniprot id: A0A5B8HGF9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

568768:Dpoa569 RS04270
gene id: 568768:Dpoa569_RS04270
uniprot id: A0A5B8I389
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

568768:Dpoa569 RS09320
gene id: 568768:Dpoa569_RS09320
uniprot id: A0A5B8IB52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

568768:Dpoa569 RS05130
gene id: 568768:Dpoa569_RS05130
uniprot id: A0A5B8HGT8
names: Subcellular Location Annotation
messages: Cytoplasm

568768:Dpoa569 RS18565
gene id: 568768:Dpoa569_RS18565
uniprot id: A0A5B8HRR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm
messages: Homodimer.

568768:Dpoa569 RS00585
gene id: 568768:Dpoa569_RS00585
uniprot id: A0A5B8HYP2
names: Function
messages: Required for maximal bacterial cellulose synthesis.

568768:Dpoa569 RS15500
gene id: 568768:Dpoa569_RS15500
uniprot id: A0A5B8I9Y2
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

568768:Dpoa569 RS13415
gene id: 568768:Dpoa569_RS13415
uniprot id: A0A5B8HQ49
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

568768:Dpoa569 RS08640
gene id: 568768:Dpoa569_RS08640
uniprot id: A0A5B8ILG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS02245
gene id: 568768:Dpoa569_RS02245
uniprot id: A0A5B8I1U9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

568768:Dpoa569 RS10145
gene id: 568768:Dpoa569_RS10145
uniprot id: A0A5B8I5A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

568768:Dpoa569 RS07215
gene id: 568768:Dpoa569_RS07215
uniprot id: A0A5B8IDL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

568768:Dpoa569 RS12685
gene id: 568768:Dpoa569_RS12685
uniprot id: A0A5B8I8B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

568768:Dpoa569 RS11995
gene id: 568768:Dpoa569_RS11995
uniprot id: A0A5B8IEN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

568768:Dpoa569 RS04435
gene id: 568768:Dpoa569_RS04435
uniprot id: A0A5B8HI44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

568768:Dpoa569 RS00085
gene id: 568768:Dpoa569_RS00085
uniprot id: A0A5B8HS97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

568768:Dpoa569 RS05935
gene id: 568768:Dpoa569_RS05935
uniprot id: A0A5B8HJS2
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS02685
gene id: 568768:Dpoa569_RS02685
uniprot id: A0A5B8I220
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

568768:Dpoa569 RS16570
gene id: 568768:Dpoa569_RS16570
uniprot id: A0A5B8IB91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

568768:Dpoa569 RS18775
gene id: 568768:Dpoa569_RS18775
uniprot id: A0A5B8IBZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

568768:Dpoa569 RS11530
gene id: 568768:Dpoa569_RS11530
uniprot id: A0A5B8ICP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

568768:Dpoa569 RS13825
gene id: 568768:Dpoa569_RS13825
uniprot id: A0A5B8I9A2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

568768:Dpoa569 RS11510
gene id: 568768:Dpoa569_RS11510
uniprot id: A0A5B8I7Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cdh family.
messages: Membrane

568768:Dpoa569 RS10430
gene id: 568768:Dpoa569_RS10430
uniprot id: A0A5B8HN72
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

568768:Dpoa569 RS00995
gene id: 568768:Dpoa569_RS00995
uniprot id: A0A5B8I5I5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

568768:Dpoa569 RS05930
gene id: 568768:Dpoa569_RS05930
uniprot id: A0A5B8I629
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

568768:Dpoa569 RS13285
gene id: 568768:Dpoa569_RS13285
uniprot id: A0A5B8I8P8
names: Subcellular Location Annotation
messages: Cell inner membrane

568768:Dpoa569 RS17420
gene id: 568768:Dpoa569_RS17420
uniprot id: A0A5B8IC47
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS09345
gene id: 568768:Dpoa569_RS09345
uniprot id: A0A5B8I4R4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

568768:Dpoa569 RS18190
gene id: 568768:Dpoa569_RS18190
uniprot id: A0A5B8IBW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

568768:Dpoa569 RS01685
gene id: 568768:Dpoa569_RS01685
uniprot id: A0A5B8I168
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

568768:Dpoa569 RS04650
gene id: 568768:Dpoa569_RS04650
uniprot id: A0A5B8HI99
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

568768:Dpoa569 RS09755
gene id: 568768:Dpoa569_RS09755
uniprot id: A0A5B8I6T2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

568768:Dpoa569 RS16820
gene id: 568768:Dpoa569_RS16820
uniprot id: A0A5B8HST5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

568768:Dpoa569 RS13135
gene id: 568768:Dpoa569_RS13135
uniprot id: A0A5B8HN88
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

568768:Dpoa569 RS05050
gene id: 568768:Dpoa569_RS05050
uniprot id: A0A5B8HJ60
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

568768:Dpoa569 RS00925
gene id: 568768:Dpoa569_RS00925
uniprot id: A0A5B8I0M8
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

568768:Dpoa569 RS05880
gene id: 568768:Dpoa569_RS05880
uniprot id: A0A5B8IAC8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

568768:Dpoa569 RS09685
gene id: 568768:Dpoa569_RS09685
uniprot id: A0A5B8I6G9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

568768:Dpoa569 RS10535
gene id: 568768:Dpoa569_RS10535
uniprot id: A0A5B8HNB0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

568768:Dpoa569 RS00690
gene id: 568768:Dpoa569_RS00690
uniprot id: A0A5B8HYS9
names: Similarity
messages: Belongs to the leucine-binding protein family.

568768:Dpoa569 RS04470
gene id: 568768:Dpoa569_RS04470
uniprot id: A0A5B8I3E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

568768:Dpoa569 RS02530
gene id: 568768:Dpoa569_RS02530
uniprot id: A0A5B8I1Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

568768:Dpoa569 RS10765
gene id: 568768:Dpoa569_RS10765
uniprot id: A0A5B8HNG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

568768:Dpoa569 RS12555
gene id: 568768:Dpoa569_RS12555
uniprot id: A0A5B8IA93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

568768:Dpoa569 RS10485
gene id: 568768:Dpoa569_RS10485
uniprot id: A0A5B8IBY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

568768:Dpoa569 RS05325
gene id: 568768:Dpoa569_RS05325
uniprot id: A0A5B8I3Z3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

568768:Dpoa569 RS00765
gene id: 568768:Dpoa569_RS00765
uniprot id: A0A5B8ID84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

568768:Dpoa569 RS01260
gene id: 568768:Dpoa569_RS01260
uniprot id: A0A5B8HEA1
names: Similarity
messages: Belongs to the UPF0438 family.

568768:Dpoa569 RS00755
gene id: 568768:Dpoa569_RS00755
uniprot id: A0A5B8HE14
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

568768:Dpoa569 RS16525
gene id: 568768:Dpoa569_RS16525
uniprot id: A0A5B8HQK1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

568768:Dpoa569 RS07640
gene id: 568768:Dpoa569_RS07640
uniprot id: A0A5B8I5B7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
messages: Cytoplasm
messages: In the transfer reaction, the free carboxyl group of lipoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Monomer.

568768:Dpoa569 RS08005
gene id: 568768:Dpoa569_RS08005
uniprot id: A0A5B8IAA2
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

568768:Dpoa569 RS02575
gene id: 568768:Dpoa569_RS02575
uniprot id: A0A5B8I1V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

568768:Dpoa569 RS08945
gene id: 568768:Dpoa569_RS08945
uniprot id: A0A5B8HLY5
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

568768:Dpoa569 RS08505
gene id: 568768:Dpoa569_RS08505
uniprot id: A0A5B8IC96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

568768:Dpoa569 RS09265
gene id: 568768:Dpoa569_RS09265
uniprot id: A0A5B8I830
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

568768:Dpoa569 RS10590
gene id: 568768:Dpoa569_RS10590
uniprot id: A0A5B8IC10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

568768:Dpoa569 RS15015
gene id: 568768:Dpoa569_RS15015
uniprot id: A0A5B8HPP8
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

568768:Dpoa569 RS00015
gene id: 568768:Dpoa569_RS00015
uniprot id: A0A5B8IBC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

568768:Dpoa569 RS13700
gene id: 568768:Dpoa569_RS13700
uniprot id: A0A5B8I9J2
names: Similarity
messages: Belongs to the YjdM family.

568768:Dpoa569 RS02445
gene id: 568768:Dpoa569_RS02445
uniprot id: A0A5B8I6T9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

568768:Dpoa569 RS11165
gene id: 568768:Dpoa569_RS11165
uniprot id: A0A5B8IE46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

568768:Dpoa569 RS02830
gene id: 568768:Dpoa569_RS02830
uniprot id: A0A5B8I294
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

568768:Dpoa569 RS01560
gene id: 568768:Dpoa569_RS01560
uniprot id: A0A5B8I669
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

568768:Dpoa569 RS07140
gene id: 568768:Dpoa569_RS07140
uniprot id: A0A5B8I508
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

568768:Dpoa569 RS10605
gene id: 568768:Dpoa569_RS10605
uniprot id: A0A5B8IDR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

568768:Dpoa569 RS13805
gene id: 568768:Dpoa569_RS13805
uniprot id: A0A5B8IE77
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

568768:Dpoa569 RS06935
gene id: 568768:Dpoa569_RS06935
uniprot id: A0A5B8HKB3
names: Function
names: Similarity
messages: Belongs to the phage GPA family.
messages: Possible endonuclease which induces a single-strand cut and initiates DNA replication.

568768:Dpoa569 RS12715
gene id: 568768:Dpoa569_RS12715
uniprot id: A0A5B8IF92
names: Similarity
messages: Belongs to the phosphohexose mutase family.

568768:Dpoa569 RS04290
gene id: 568768:Dpoa569_RS04290
uniprot id: A0A5B8HGC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

568768:Dpoa569 RS01645
gene id: 568768:Dpoa569_RS01645
uniprot id: A0A5B8HFW6
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

568768:Dpoa569 RS15630
gene id: 568768:Dpoa569_RS15630
uniprot id: A0A5B8IHL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

568768:Dpoa569 RS02470
gene id: 568768:Dpoa569_RS02470
uniprot id: A0A5B8HF27
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

568768:Dpoa569 RS01075
gene id: 568768:Dpoa569_RS01075
uniprot id: A0A5B8I0Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

568768:Dpoa569 RS16540
gene id: 568768:Dpoa569_RS16540
uniprot id: A0A5B8II53
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

568768:Dpoa569 RS04680
gene id: 568768:Dpoa569_RS04680
uniprot id: A0A5B8I1Q5
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

568768:Dpoa569 RS11580
gene id: 568768:Dpoa569_RS11580
uniprot id: A0A5B8ICQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

568768:Dpoa569 RS02385
gene id: 568768:Dpoa569_RS02385
uniprot id: A0A5B8HEX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

568768:Dpoa569 RS07900
gene id: 568768:Dpoa569_RS07900
uniprot id: A0A5B8I772
names: Similarity
messages: Belongs to the peptidase C40 family.

568768:Dpoa569 RS04620
gene id: 568768:Dpoa569_RS04620
uniprot id: A0A5B8I3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

568768:Dpoa569 RS15830
gene id: 568768:Dpoa569_RS15830
uniprot id: A0A5B8HQ50
names: Similarity
messages: Belongs to the GST superfamily.

568768:Dpoa569 RS16420
gene id: 568768:Dpoa569_RS16420
uniprot id: A0A5B8II32
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

568768:Dpoa569 RS14805
gene id: 568768:Dpoa569_RS14805
uniprot id: A0A5B8IEV4
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

568768:Dpoa569 RS04280
gene id: 568768:Dpoa569_RS04280
uniprot id: A0A5B8I3A8
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

568768:Dpoa569 RS19275
gene id: 568768:Dpoa569_RS19275
uniprot id: A0A5B8HUG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS07325
gene id: 568768:Dpoa569_RS07325
uniprot id: A0A5B8I500
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

568768:Dpoa569 RS17060
gene id: 568768:Dpoa569_RS17060
uniprot id: A0A5B8IB71
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

568768:Dpoa569 RS09120
gene id: 568768:Dpoa569_RS09120
uniprot id: A0A5B8I4L4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

568768:Dpoa569 RS14040
gene id: 568768:Dpoa569_RS14040
uniprot id: A0A5B8I9E6
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS11900
gene id: 568768:Dpoa569_RS11900
uniprot id: A0A5B8I6E3
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS02040
gene id: 568768:Dpoa569_RS02040
uniprot id: A0A5B8I1K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrF/TusC family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

568768:Dpoa569 RS15390
gene id: 568768:Dpoa569_RS15390
uniprot id: A0A5B8HRY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

568768:Dpoa569 RS12960
gene id: 568768:Dpoa569_RS12960
uniprot id: A0A5B8IFI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

568768:Dpoa569 RS03640
gene id: 568768:Dpoa569_RS03640
uniprot id: A0A5B8I2U2
names: Similarity
messages: Belongs to the GSP E family.

568768:Dpoa569 RS01255
gene id: 568768:Dpoa569_RS01255
uniprot id: A0A5B8I0V2
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

568768:Dpoa569 RS15525
gene id: 568768:Dpoa569_RS15525
uniprot id: A0A5B8HRD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

568768:Dpoa569 RS10185
gene id: 568768:Dpoa569_RS10185
uniprot id: A0A5B8IDH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

568768:Dpoa569 RS07385
gene id: 568768:Dpoa569_RS07385
uniprot id: A0A5B8HKB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

568768:Dpoa569 RS16575
gene id: 568768:Dpoa569_RS16575
uniprot id: A0A5B8IAN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

568768:Dpoa569 RS02185
gene id: 568768:Dpoa569_RS02185
uniprot id: A0A5B8HGA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

568768:Dpoa569 RS12640
gene id: 568768:Dpoa569_RS12640
uniprot id: A0A5B8HMT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

568768:Dpoa569 RS14440
gene id: 568768:Dpoa569_RS14440
uniprot id: A0A5B8I9C9
names: Similarity
messages: Belongs to the peptidase A24 family.

568768:Dpoa569 RS13375
gene id: 568768:Dpoa569_RS13375
uniprot id: A0A5B8I927
names: Subcellular Location Annotation
messages: Membrane

568768:Dpoa569 RS12690
gene id: 568768:Dpoa569_RS12690
uniprot id: A0A5B8HMV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

568768:Dpoa569 RS19170
gene id: 568768:Dpoa569_RS19170
uniprot id: A0A5B8HS35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

568768:Dpoa569 RS15650
gene id: 568768:Dpoa569_RS15650
uniprot id: A0A5B8IA17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

568768:Dpoa569 RS02855
gene id: 568768:Dpoa569_RS02855
uniprot id: A0A5B8HGU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

568768:Dpoa569 RS11155
gene id: 568768:Dpoa569_RS11155
uniprot id: A0A5B8HNP7
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

568768:Dpoa569 RS16815
gene id: 568768:Dpoa569_RS16815
uniprot id: A0A5B8HQQ6
names: Similarity
messages: Belongs to the pirin family.

568768:Dpoa569 RS10915
gene id: 568768:Dpoa569_RS10915
uniprot id: A0A5B8I7B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

568768:Dpoa569 RS15985
gene id: 568768:Dpoa569_RS15985
uniprot id: A0A5B8IAB7
names: Similarity
messages: Belongs to the YciI family.

568768:Dpoa569 RS16870
gene id: 568768:Dpoa569_RS16870
uniprot id: A0A5B8HSV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

568768:Dpoa569 RS07230
gene id: 568768:Dpoa569_RS07230
uniprot id: A0A5B8I6S8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.