56780:SYN RS04515
gene id: 56780:SYN_RS04515
uniprot id: Q2LRX3
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

56780:SYN RS14135
gene id: 56780:SYN_RS14135
uniprot id: Q2LXS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity.

56780:SYN RS07270
gene id: 56780:SYN_RS07270
uniprot id: Q2LTJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

56780:SYN RS01415
gene id: 56780:SYN_RS01415
uniprot id: Q2LQ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

56780:SYN RS08980
gene id: 56780:SYN_RS08980
uniprot id: Q2LUK3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

56780:SYN RS14340
gene id: 56780:SYN_RS14340
uniprot id: Q2LXX1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

56780:SYN RS08860
gene id: 56780:SYN_RS08860
uniprot id: Q2LUH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

56780:SYN RS08605
gene id: 56780:SYN_RS08605
uniprot id: Q2LUC0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

56780:SYN RS05770
gene id: 56780:SYN_RS05770
uniprot id: Q2LSN9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

56780:SYN RS14630
gene id: 56780:SYN_RS14630
uniprot id: Q2LY41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

56780:SYN RS04505
gene id: 56780:SYN_RS04505
uniprot id: Q2LRX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

56780:SYN RS02965
gene id: 56780:SYN_RS02965
uniprot id: Q2LQZ4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

56780:SYN RS07460
gene id: 56780:SYN_RS07460
uniprot id: Q2LTN0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

56780:SYN RS05860
gene id: 56780:SYN_RS05860
uniprot id: Q2LSR0
names: Similarity
messages: Belongs to the AdoMet synthase family.

56780:SYN RS03005
gene id: 56780:SYN_RS03005
uniprot id: Q2LQZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

56780:SYN RS08430
gene id: 56780:SYN_RS08430
uniprot id: Q2LU82
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

56780:SYN RS04190
gene id: 56780:SYN_RS04190
uniprot id: Q2LRQ6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

56780:SYN RS08215
gene id: 56780:SYN_RS08215
uniprot id: Q2LU42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

56780:SYN RS10715
gene id: 56780:SYN_RS10715
uniprot id: Q2LVM1
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS01375
gene id: 56780:SYN_RS01375
uniprot id: Q2LQ77
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

56780:SYN RS02640
gene id: 56780:SYN_RS02640
uniprot id: Q2LQS3
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

56780:SYN RS05910
gene id: 56780:SYN_RS05910
uniprot id: Q2LSR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

56780:SYN RS07130
gene id: 56780:SYN_RS07130
uniprot id: Q2LTH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

56780:SYN RS14235
gene id: 56780:SYN_RS14235
uniprot id: Q2LXU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

56780:SYN RS05395
gene id: 56780:SYN_RS05395
uniprot id: Q2LSG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

56780:SYN RS03200
gene id: 56780:SYN_RS03200
uniprot id: Q2LR40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

56780:SYN RS14110
gene id: 56780:SYN_RS14110
uniprot id: Q2LXR7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

56780:SYN RS04475
gene id: 56780:SYN_RS04475
uniprot id: Q2LRW4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

56780:SYN RS11250
gene id: 56780:SYN_RS11250
uniprot id: Q2LVY0
names: Similarity
messages: Belongs to the HypE family.

56780:SYN RS07555
gene id: 56780:SYN_RS07555
uniprot id: Q2LTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

56780:SYN RS11870
gene id: 56780:SYN_RS11870
uniprot id: Q2LWC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

56780:SYN RS10505
gene id: 56780:SYN_RS10505
uniprot id: Q2LVH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

56780:SYN RS00345
gene id: 56780:SYN_RS00345
uniprot id: Q2LYC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS00395
gene id: 56780:SYN_RS00395
uniprot id: Q2LYF5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

56780:SYN RS00990
gene id: 56780:SYN_RS00990
uniprot id: Q2LY96
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

56780:SYN RS01530
gene id: 56780:SYN_RS01530
uniprot id: Q2LQA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

56780:SYN RS01455
gene id: 56780:SYN_RS01455
uniprot id: Q2LQA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

56780:SYN RS13710
gene id: 56780:SYN_RS13710
uniprot id: Q2LXI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

56780:SYN RS01255
gene id: 56780:SYN_RS01255
uniprot id: Q2LQ56
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

56780:SYN RS13560
gene id: 56780:SYN_RS13560
uniprot id: Q2LXF2
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

56780:SYN RS14585
gene id: 56780:SYN_RS14585
uniprot id: Q2LY31
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

56780:SYN RS06360
gene id: 56780:SYN_RS06360
uniprot id: Q2LT12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

56780:SYN RS05760
gene id: 56780:SYN_RS05760
uniprot id: Q2LSN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

56780:SYN RS06740
gene id: 56780:SYN_RS06740
uniprot id: Q2LT86
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

56780:SYN RS06725
gene id: 56780:SYN_RS06725
uniprot id: Q2LT89
names: Similarity
messages: Belongs to the AOR/FOR family.

56780:SYN RS02200
gene id: 56780:SYN_RS02200
uniprot id: Q2LPX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

56780:SYN RS13245
gene id: 56780:SYN_RS13245
uniprot id: Q2LX89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

56780:SYN RS06160
gene id: 56780:SYN_RS06160
uniprot id: Q2LSW7
names: Similarity
messages: Belongs to the peptidase C40 family.

56780:SYN RS06760
gene id: 56780:SYN_RS06760
uniprot id: Q2LT92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

56780:SYN RS07530
gene id: 56780:SYN_RS07530
uniprot id: Q2LTP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

56780:SYN RS06770
gene id: 56780:SYN_RS06770
uniprot id: Q2LT90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

56780:SYN RS07255
gene id: 56780:SYN_RS07255
uniprot id: Q2LTJ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

56780:SYN RS07650
gene id: 56780:SYN_RS07650
uniprot id: Q2LTS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

56780:SYN RS15005
gene id: 56780:SYN_RS15005
uniprot id: Q2LQX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

56780:SYN RS01425
gene id: 56780:SYN_RS01425
uniprot id: Q2LQ91
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

56780:SYN RS13685
gene id: 56780:SYN_RS13685
uniprot id: Q2LXI1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

56780:SYN RS05975
gene id: 56780:SYN_RS05975
uniprot id: Q2LSS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

56780:SYN RS06400
gene id: 56780:SYN_RS06400
uniprot id: Q2LT22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

56780:SYN RS04180
gene id: 56780:SYN_RS04180
uniprot id: Q2LRP9
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

56780:SYN RS13405
gene id: 56780:SYN_RS13405
uniprot id: Q2LXB6
names: Similarity
messages: Belongs to the DEAD box helicase family.

56780:SYN RS00860
gene id: 56780:SYN_RS00860
uniprot id: Q2LQK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

56780:SYN RS08880
gene id: 56780:SYN_RS08880
uniprot id: Q2LUH6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

56780:SYN RS00450
gene id: 56780:SYN_RS00450
uniprot id: Q2LYA7
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS01495
gene id: 56780:SYN_RS01495
uniprot id: Q2LQ96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

56780:SYN RS00235
gene id: 56780:SYN_RS00235
uniprot id: Q2LPJ9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

56780:SYN RS11930
gene id: 56780:SYN_RS11930
uniprot id: Q2LWE2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

56780:SYN RS09370
gene id: 56780:SYN_RS09370
uniprot id: Q2LUS9
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

56780:SYN RS08675
gene id: 56780:SYN_RS08675
uniprot id: Q2LUD3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS12080
gene id: 56780:SYN_RS12080
uniprot id: Q2LWG9
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS01650
gene id: 56780:SYN_RS01650
uniprot id: Q2LPL7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

56780:SYN RS11750
gene id: 56780:SYN_RS11750
uniprot id: Q2LWA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

56780:SYN RS06290
gene id: 56780:SYN_RS06290
uniprot id: Q2LSZ6
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

56780:SYN RS13970
gene id: 56780:SYN_RS13970
uniprot id: Q2LXP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

56780:SYN RS05480
gene id: 56780:SYN_RS05480
uniprot id: Q2LSI2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

56780:SYN RS04510
gene id: 56780:SYN_RS04510
uniprot id: Q2LRX4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

56780:SYN RS13105
gene id: 56780:SYN_RS13105
uniprot id: Q2LX49
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

56780:SYN RS14760
gene id: 56780:SYN_RS14760
uniprot id: Q2LY69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

56780:SYN RS05370
gene id: 56780:SYN_RS05370
uniprot id: Q2LSF7
names: Similarity
messages: Belongs to the histone deacetylase family.

56780:SYN RS07005
gene id: 56780:SYN_RS07005
uniprot id: Q2LTE2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

56780:SYN RS02720
gene id: 56780:SYN_RS02720
uniprot id: Q2LQT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

56780:SYN RS09215
gene id: 56780:SYN_RS09215
uniprot id: Q2LUP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

56780:SYN RS03705
gene id: 56780:SYN_RS03705
uniprot id: Q2LRF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

56780:SYN RS13320
gene id: 56780:SYN_RS13320
uniprot id: Q2LXA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

56780:SYN RS09295
gene id: 56780:SYN_RS09295
uniprot id: Q2LUR5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

56780:SYN RS10630
gene id: 56780:SYN_RS10630
uniprot id: Q2LVK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

56780:SYN RS05040
gene id: 56780:SYN_RS05040
uniprot id: Q2LS90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

56780:SYN RS05630
gene id: 56780:SYN_RS05630
uniprot id: Q2LSL4
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

56780:SYN RS01545
gene id: 56780:SYN_RS01545
uniprot id: Q2LQC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

56780:SYN RS12635
gene id: 56780:SYN_RS12635
uniprot id: Q2LWT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

56780:SYN RS14170
gene id: 56780:SYN_RS14170
uniprot id: Q2LXT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

56780:SYN RS09100
gene id: 56780:SYN_RS09100
uniprot id: Q2LUM6
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

56780:SYN RS08655
gene id: 56780:SYN_RS08655
uniprot id: Q2LUC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

56780:SYN RS08670
gene id: 56780:SYN_RS08670
uniprot id: Q2LUD4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS07085
gene id: 56780:SYN_RS07085
uniprot id: Q2LTG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

56780:SYN RS03630
gene id: 56780:SYN_RS03630
uniprot id: Q2LRD2
names: Similarity
messages: Belongs to the pyruvate kinase family.

56780:SYN RS14800
gene id: 56780:SYN_RS14800
uniprot id: Q2LY71
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS10670
gene id: 56780:SYN_RS10670
uniprot id: Q2LVL1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

56780:SYN RS12675
gene id: 56780:SYN_RS12675
uniprot id: Q2LWU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

56780:SYN RS10665
gene id: 56780:SYN_RS10665
uniprot id: Q2LVL2
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS11610
gene id: 56780:SYN_RS11610
uniprot id: Q2LW73
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS08875
gene id: 56780:SYN_RS08875
uniprot id: Q2LUH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

56780:SYN RS04075
gene id: 56780:SYN_RS04075
uniprot id: Q2LRM7
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS10495
gene id: 56780:SYN_RS10495
uniprot id: Q2LVH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

56780:SYN RS01575
gene id: 56780:SYN_RS01575
uniprot id: Q2LQB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

56780:SYN RS01555
gene id: 56780:SYN_RS01555
uniprot id: Q2LQB9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

56780:SYN RS11280
gene id: 56780:SYN_RS11280
uniprot id: Q2LVZ2
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

56780:SYN RS11240
gene id: 56780:SYN_RS11240
uniprot id: Q2LVY2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

56780:SYN RS09225
gene id: 56780:SYN_RS09225
uniprot id: Q2LUP7
names: Similarity
messages: Belongs to the gamma-class carbonic anhydrase family.

56780:SYN RS01535
gene id: 56780:SYN_RS01535
uniprot id: Q2LQA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

56780:SYN RS05285
gene id: 56780:SYN_RS05285
uniprot id: Q2LSD8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

56780:SYN RS00910
gene id: 56780:SYN_RS00910
uniprot id: Q2LQM3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

56780:SYN RS06705
gene id: 56780:SYN_RS06705
uniprot id: Q2LT84
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

56780:SYN RS13435
gene id: 56780:SYN_RS13435
uniprot id: Q2LXC0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

56780:SYN RS00900
gene id: 56780:SYN_RS00900
uniprot id: Q2LQM5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

56780:SYN RS03080
gene id: 56780:SYN_RS03080
uniprot id: Q2LR12
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

56780:SYN RS12505
gene id: 56780:SYN_RS12505
uniprot id: Q2LWR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

56780:SYN RS12570
gene id: 56780:SYN_RS12570
uniprot id: Q2LWS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

56780:SYN RS08305
gene id: 56780:SYN_RS08305
uniprot id: Q2LU54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

56780:SYN RS10605
gene id: 56780:SYN_RS10605
uniprot id: Q2LVJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

56780:SYN RS12470
gene id: 56780:SYN_RS12470
uniprot id: Q2LWQ0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

56780:SYN RS05840
gene id: 56780:SYN_RS05840
uniprot id: Q2LSQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

56780:SYN RS08990
gene id: 56780:SYN_RS08990
uniprot id: Q2LUK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

56780:SYN RS13020
gene id: 56780:SYN_RS13020
uniprot id: Q2LX30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

56780:SYN RS15270
gene id: 56780:SYN_RS15270
uniprot id: Q2LTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

56780:SYN RS05870
gene id: 56780:SYN_RS05870
uniprot id: Q2LSQ8
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS11760
gene id: 56780:SYN_RS11760
uniprot id: Q2LW98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

56780:SYN RS01335
gene id: 56780:SYN_RS01335
uniprot id: Q2LQ63
names: Similarity
messages: Belongs to the YicC/YloC family.

56780:SYN RS03640
gene id: 56780:SYN_RS03640
uniprot id: Q2LRD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

56780:SYN RS00870
gene id: 56780:SYN_RS00870
uniprot id: Q2LQN1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

56780:SYN RS00055
gene id: 56780:SYN_RS00055
uniprot id: Q2LQH4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

56780:SYN RS14100
gene id: 56780:SYN_RS14100
uniprot id: Q2LXS0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

56780:SYN RS03770
gene id: 56780:SYN_RS03770
uniprot id: Q2LRG4
names: Similarity
messages: Belongs to the ribF family.

56780:SYN RS12705
gene id: 56780:SYN_RS12705
uniprot id: Q2LWU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

56780:SYN RS05925
gene id: 56780:SYN_RS05925
uniprot id: Q2LSR6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

56780:SYN RS00030
gene id: 56780:SYN_RS00030
uniprot id: Q2LQH9
names: Similarity
messages: Belongs to the archease family.

56780:SYN RS11560
gene id: 56780:SYN_RS11560
uniprot id: Q2LW63
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS04535
gene id: 56780:SYN_RS04535
uniprot id: Q2LRX9
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

56780:SYN RS09000
gene id: 56780:SYN_RS09000
uniprot id: Q2LUJ9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

56780:SYN RS09340
gene id: 56780:SYN_RS09340
uniprot id: Q2LUS7
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

56780:SYN RS13310
gene id: 56780:SYN_RS13310
uniprot id: Q2LX95
names: Similarity
messages: Belongs to the cytochrome c-552 family.

56780:SYN RS05675
gene id: 56780:SYN_RS05675
uniprot id: Q2LSM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

56780:SYN RS10380
gene id: 56780:SYN_RS10380
uniprot id: Q2LVE4
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

56780:SYN RS12655
gene id: 56780:SYN_RS12655
uniprot id: Q2LWT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

56780:SYN RS11235
gene id: 56780:SYN_RS11235
uniprot id: Q2LVY3
names: Similarity
messages: Belongs to the HypD family.

56780:SYN RS14515
gene id: 56780:SYN_RS14515
uniprot id: Q2LY17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

56780:SYN RS06985
gene id: 56780:SYN_RS06985
uniprot id: Q2LTD6
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS12025
gene id: 56780:SYN_RS12025
uniprot id: Q2LWG2
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

56780:SYN RS05385
gene id: 56780:SYN_RS05385
uniprot id: Q2LSF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

56780:SYN RS08345
gene id: 56780:SYN_RS08345
uniprot id: Q2LU64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

56780:SYN RS02780
gene id: 56780:SYN_RS02780
uniprot id: Q2LQV4
names: Similarity
messages: Belongs to the Ahb/Nir family.

56780:SYN RS00035
gene id: 56780:SYN_RS00035
uniprot id: Q2LQH8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

56780:SYN RS08250
gene id: 56780:SYN_RS08250
uniprot id: Q2LU46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

56780:SYN RS11920
gene id: 56780:SYN_RS11920
uniprot id: Q2LWD5
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

56780:SYN RS04595
gene id: 56780:SYN_RS04595
uniprot id: Q2LRY8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

56780:SYN RS08920
gene id: 56780:SYN_RS08920
uniprot id: Q2LUI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

56780:SYN RS00600
gene id: 56780:SYN_RS00600
uniprot id: Q2LYD7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

56780:SYN RS12345
gene id: 56780:SYN_RS12345
uniprot id: Q2LWM2
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

56780:SYN RS10980
gene id: 56780:SYN_RS10980
uniprot id: Q2LVS4
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS08500
gene id: 56780:SYN_RS08500
uniprot id: Q2LU94
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

56780:SYN RS01540
gene id: 56780:SYN_RS01540
uniprot id: Q2LQC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

56780:SYN RS12155
gene id: 56780:SYN_RS12155
uniprot id: Q2LWJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

56780:SYN RS11225
gene id: 56780:SYN_RS11225
uniprot id: Q2LVX4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

56780:SYN RS03085
gene id: 56780:SYN_RS03085
uniprot id: Q2LR11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

56780:SYN RS13935
gene id: 56780:SYN_RS13935
uniprot id: Q2LXN0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

56780:SYN RS06305
gene id: 56780:SYN_RS06305
uniprot id: Q2LT03
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

56780:SYN RS00770
gene id: 56780:SYN_RS00770
uniprot id: Q2LPH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

56780:SYN RS05690
gene id: 56780:SYN_RS05690
uniprot id: Q2LSM1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

56780:SYN RS01070
gene id: 56780:SYN_RS01070
uniprot id: Q2LQI6
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

56780:SYN RS13940
gene id: 56780:SYN_RS13940
uniprot id: Q2LXM9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

56780:SYN RS14140
gene id: 56780:SYN_RS14140
uniprot id: Q2LXS7
names: Similarity
messages: Belongs to the CFA/CMAS family.

56780:SYN RS03995
gene id: 56780:SYN_RS03995
uniprot id: Q2LRL2
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

56780:SYN RS13400
gene id: 56780:SYN_RS13400
uniprot id: Q2LXB7
names: Subcellular Location Annotation
messages: Cytoplasm

56780:SYN RS12420
gene id: 56780:SYN_RS12420
uniprot id: Q2LWP3
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

56780:SYN RS13305
gene id: 56780:SYN_RS13305
uniprot id: Q2LX96
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS07585
gene id: 56780:SYN_RS07585
uniprot id: Q2LTQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

56780:SYN RS05635
gene id: 56780:SYN_RS05635
uniprot id: Q2LSL3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

56780:SYN RS00400
gene id: 56780:SYN_RS00400
uniprot id: Q2LYF4
names: Similarity
messages: Belongs to the class-I fumarase family.

56780:SYN RS09120
gene id: 56780:SYN_RS09120
uniprot id: Q2LUM2
names: Subunit
messages: Homodimer.

56780:SYN RS10730
gene id: 56780:SYN_RS10730
uniprot id: Q2LVM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

56780:SYN RS04680
gene id: 56780:SYN_RS04680
uniprot id: Q2LS08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

56780:SYN RS10545
gene id: 56780:SYN_RS10545
uniprot id: Q2LVI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

56780:SYN RS13965
gene id: 56780:SYN_RS13965
uniprot id: Q2LXP1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

56780:SYN RS03190
gene id: 56780:SYN_RS03190
uniprot id: Q2LR42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

56780:SYN RS03245
gene id: 56780:SYN_RS03245
uniprot id: Q2LR48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

56780:SYN RS14545
gene id: 56780:SYN_RS14545
uniprot id: Q2LY21
names: Similarity
messages: Belongs to the UPF0111 family.

56780:SYN RS01380
gene id: 56780:SYN_RS01380
uniprot id: Q2LQ76
names: Similarity
messages: Belongs to the MEMO1 family.

56780:SYN RS01110
gene id: 56780:SYN_RS01110
uniprot id: Q2LQN6
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS13550
gene id: 56780:SYN_RS13550
uniprot id: Q2LXE4
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS07675
gene id: 56780:SYN_RS07675
uniprot id: Q2LTS7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

56780:SYN RS00220
gene id: 56780:SYN_RS00220
uniprot id: Q2LQJ5
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS12690
gene id: 56780:SYN_RS12690
uniprot id: Q2LWV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

56780:SYN RS08160
gene id: 56780:SYN_RS08160
uniprot id: Q2LU30
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

56780:SYN RS06950
gene id: 56780:SYN_RS06950
uniprot id: Q2LTD3
names: Subcellular Location Annotation
messages: Cytoplasm

56780:SYN RS02945
gene id: 56780:SYN_RS02945
uniprot id: Q2LQY8
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

56780:SYN RS04895
gene id: 56780:SYN_RS04895
uniprot id: Q2LS52
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS00850
gene id: 56780:SYN_RS00850
uniprot id: Q2LQK7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

56780:SYN RS07340
gene id: 56780:SYN_RS07340
uniprot id: Q2LTK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

56780:SYN RS08975
gene id: 56780:SYN_RS08975
uniprot id: Q2LUJ4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

56780:SYN RS08185
gene id: 56780:SYN_RS08185
uniprot id: Q2LU31
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

56780:SYN RS09530
gene id: 56780:SYN_RS09530
uniprot id: Q2LUW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

56780:SYN RS00685
gene id: 56780:SYN_RS00685
uniprot id: Q2LQE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

56780:SYN RS01320
gene id: 56780:SYN_RS01320
uniprot id: Q2LQ67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

56780:SYN RS10975
gene id: 56780:SYN_RS10975
uniprot id: Q2LVS5
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS01735
gene id: 56780:SYN_RS01735
uniprot id: Q2LPP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

56780:SYN RS06320
gene id: 56780:SYN_RS06320
uniprot id: Q2LT00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

56780:SYN RS12700
gene id: 56780:SYN_RS12700
uniprot id: Q2LWU9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

56780:SYN RS00690
gene id: 56780:SYN_RS00690
uniprot id: Q2LQE5
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

56780:SYN RS07120
gene id: 56780:SYN_RS07120
uniprot id: Q2LTG6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

56780:SYN RS10840
gene id: 56780:SYN_RS10840
uniprot id: Q2LVP4
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS12785
gene id: 56780:SYN_RS12785
uniprot id: Q2LWW6
names: Similarity
messages: Belongs to the RutC family.

56780:SYN RS10695
gene id: 56780:SYN_RS10695
uniprot id: Q2LVL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

56780:SYN RS14435
gene id: 56780:SYN_RS14435
uniprot id: Q2LXZ7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

56780:SYN RS06210
gene id: 56780:SYN_RS06210
uniprot id: Q2LSX6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

56780:SYN RS07315
gene id: 56780:SYN_RS07315
uniprot id: Q2LTK4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

56780:SYN RS11065
gene id: 56780:SYN_RS11065
uniprot id: Q2LVU4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

56780:SYN RS01720
gene id: 56780:SYN_RS01720
uniprot id: Q2LPM4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

56780:SYN RS03070
gene id: 56780:SYN_RS03070
uniprot id: Q2LR14
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

56780:SYN RS05695
gene id: 56780:SYN_RS05695
uniprot id: Q2LSM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

56780:SYN RS00635
gene id: 56780:SYN_RS00635
uniprot id: Q2LPI3
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

56780:SYN RS07260
gene id: 56780:SYN_RS07260
uniprot id: Q2LTJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

56780:SYN RS00625
gene id: 56780:SYN_RS00625
uniprot id: Q2LPI5
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

56780:SYN RS01445
gene id: 56780:SYN_RS01445
uniprot id: Q2LQ87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

56780:SYN RS14620
gene id: 56780:SYN_RS14620
uniprot id: Q2LY34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

56780:SYN RS07240
gene id: 56780:SYN_RS07240
uniprot id: Q2LTJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

56780:SYN RS13535
gene id: 56780:SYN_RS13535
uniprot id: Q2LXD8
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS14395
gene id: 56780:SYN_RS14395
uniprot id: Q2LXY8
names: Similarity
messages: Belongs to the glutamine synthetase family.

56780:SYN RS12725
gene id: 56780:SYN_RS12725
uniprot id: Q2LWV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

56780:SYN RS08910
gene id: 56780:SYN_RS08910
uniprot id: Q2LUI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

56780:SYN RS06890
gene id: 56780:SYN_RS06890
uniprot id: Q2LTB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

56780:SYN RS01790
gene id: 56780:SYN_RS01790
uniprot id: Q2LPQ4
names: Similarity
messages: Belongs to the peptidase S16 family.

56780:SYN RS15215
gene id: 56780:SYN_RS15215
uniprot id: Q2LT05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

56780:SYN RS13125
gene id: 56780:SYN_RS13125
uniprot id: Q2LX53
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

56780:SYN RS09650
gene id: 56780:SYN_RS09650
uniprot id: Q2LUY8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

56780:SYN RS08390
gene id: 56780:SYN_RS08390
uniprot id: Q2LU73
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

56780:SYN RS07275
gene id: 56780:SYN_RS07275
uniprot id: Q2LTJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

56780:SYN RS07410
gene id: 56780:SYN_RS07410
uniprot id: Q2LTM0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

56780:SYN RS14580
gene id: 56780:SYN_RS14580
uniprot id: Q2LY23
names: Similarity
messages: Belongs to the DEAD box helicase family.

56780:SYN RS03960
gene id: 56780:SYN_RS03960
uniprot id: Q2LRK7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

56780:SYN RS12645
gene id: 56780:SYN_RS12645
uniprot id: Q2LWU1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

56780:SYN RS15495
gene id: 56780:SYN_RS15495
uniprot id: Q2LX92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

56780:SYN RS13945
gene id: 56780:SYN_RS13945
uniprot id: Q2LXN4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

56780:SYN RS14465
gene id: 56780:SYN_RS14465
uniprot id: Q2LXZ9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

56780:SYN RS11150
gene id: 56780:SYN_RS11150
uniprot id: Q2LVW3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

56780:SYN RS12835
gene id: 56780:SYN_RS12835
uniprot id: Q2LWY4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

56780:SYN RS00545
gene id: 56780:SYN_RS00545
uniprot id: Q2LYG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

56780:SYN RS07125
gene id: 56780:SYN_RS07125
uniprot id: Q2LTG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

56780:SYN RS07225
gene id: 56780:SYN_RS07225
uniprot id: Q2LTI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

56780:SYN RS09275
gene id: 56780:SYN_RS09275
uniprot id: Q2LUR3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

56780:SYN RS07280
gene id: 56780:SYN_RS07280
uniprot id: Q2LTK0
names: Similarity
messages: Belongs to the aspartokinase family.

56780:SYN RS10780
gene id: 56780:SYN_RS10780
uniprot id: Q2LVN8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

56780:SYN RS08915
gene id: 56780:SYN_RS08915
uniprot id: Q2LUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

56780:SYN RS02355
gene id: 56780:SYN_RS02355
uniprot id: Q2LQM0
names: Similarity
messages: Belongs to the YciI family.

56780:SYN RS04095
gene id: 56780:SYN_RS04095
uniprot id: Q2LRN1
names: Similarity
messages: Belongs to the UPF0434 family.

56780:SYN RS13810
gene id: 56780:SYN_RS13810
uniprot id: Q2LXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

56780:SYN RS03530
gene id: 56780:SYN_RS03530
uniprot id: Q2LRB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

56780:SYN RS07725
gene id: 56780:SYN_RS07725
uniprot id: Q2LTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

56780:SYN RS00890
gene id: 56780:SYN_RS00890
uniprot id: Q2LQM7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

56780:SYN RS01520
gene id: 56780:SYN_RS01520
uniprot id: Q2LQB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

56780:SYN RS07715
gene id: 56780:SYN_RS07715
uniprot id: Q2LTT8
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

56780:SYN RS02890
gene id: 56780:SYN_RS02890
uniprot id: Q2LQY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

56780:SYN RS11175
gene id: 56780:SYN_RS11175
uniprot id: Q2LVW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

56780:SYN RS11890
gene id: 56780:SYN_RS11890
uniprot id: Q2LWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

56780:SYN RS08540
gene id: 56780:SYN_RS08540
uniprot id: Q2LUA5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

56780:SYN RS00960
gene id: 56780:SYN_RS00960
uniprot id: Q2LQF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS12630
gene id: 56780:SYN_RS12630
uniprot id: Q2LWT5
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

56780:SYN RS07605
gene id: 56780:SYN_RS07605
uniprot id: Q2LTR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS11180
gene id: 56780:SYN_RS11180
uniprot id: Q2LVW5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS01230
gene id: 56780:SYN_RS01230
uniprot id: Q2LQ36
names: Similarity
messages: Belongs to the transketolase family.

56780:SYN RS11265
gene id: 56780:SYN_RS11265
uniprot id: Q2LVY6
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

56780:SYN RS01105
gene id: 56780:SYN_RS01105
uniprot id: Q2LQN7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS01600
gene id: 56780:SYN_RS01600
uniprot id: Q2LQC8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

56780:SYN RS07445
gene id: 56780:SYN_RS07445
uniprot id: Q2LTN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

56780:SYN RS05005
gene id: 56780:SYN_RS05005
uniprot id: Q2LS81
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

56780:SYN RS04610
gene id: 56780:SYN_RS04610
uniprot id: Q2LRZ4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

56780:SYN RS02350
gene id: 56780:SYN_RS02350
uniprot id: Q2LQM1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

56780:SYN RS03000
gene id: 56780:SYN_RS03000
uniprot id: Q2LQZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

56780:SYN RS07720
gene id: 56780:SYN_RS07720
uniprot id: Q2LTT7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

56780:SYN RS01340
gene id: 56780:SYN_RS01340
uniprot id: Q2LQ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

56780:SYN RS16830
gene id: 56780:SYN_RS16830
uniprot id: Q2LW91
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Homooctamer; dimer of tetramers.

56780:SYN RS07640
gene id: 56780:SYN_RS07640
uniprot id: Q2LTS5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

56780:SYN RS00025
gene id: 56780:SYN_RS00025
uniprot id: Q2LYA0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

56780:SYN RS00995
gene id: 56780:SYN_RS00995
uniprot id: Q2LY95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS11790
gene id: 56780:SYN_RS11790
uniprot id: Q2LWA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

56780:SYN RS07630
gene id: 56780:SYN_RS07630
uniprot id: Q2LTR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

56780:SYN RS12810
gene id: 56780:SYN_RS12810
uniprot id: Q2LWX9
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

56780:SYN RS05730
gene id: 56780:SYN_RS05730
uniprot id: Q2LSN3
names: Similarity
messages: Belongs to the sigma-54 factor family.

56780:SYN RS01560
gene id: 56780:SYN_RS01560
uniprot id: Q2LQB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

56780:SYN RS11080
gene id: 56780:SYN_RS11080
uniprot id: Q2LVU6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

56780:SYN RS13790
gene id: 56780:SYN_RS13790
uniprot id: Q2LXK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

56780:SYN RS08460
gene id: 56780:SYN_RS08460
uniprot id: Q2LU85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

56780:SYN RS09030
gene id: 56780:SYN_RS09030
uniprot id: Q2LUL1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

56780:SYN RS03015
gene id: 56780:SYN_RS03015
uniprot id: Q2LR04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

56780:SYN RS14805
gene id: 56780:SYN_RS14805
uniprot id: Q2LY78
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS00075
gene id: 56780:SYN_RS00075
uniprot id: Q2LQI3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

56780:SYN RS05105
gene id: 56780:SYN_RS05105
uniprot id: Q2LS96
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS13130
gene id: 56780:SYN_RS13130
uniprot id: Q2LX57
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

56780:SYN RS10405
gene id: 56780:SYN_RS10405
uniprot id: Q2LVE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

56780:SYN RS09010
gene id: 56780:SYN_RS09010
uniprot id: Q2LUK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

56780:SYN RS00620
gene id: 56780:SYN_RS00620
uniprot id: Q2LPI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

56780:SYN RS06885
gene id: 56780:SYN_RS06885
uniprot id: Q2LTC0
names: Subcellular Location Annotation
messages: Cytoplasm

56780:SYN RS02990
gene id: 56780:SYN_RS02990
uniprot id: Q2LQZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

56780:SYN RS13980
gene id: 56780:SYN_RS13980
uniprot id: Q2LXP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

56780:SYN RS12195
gene id: 56780:SYN_RS12195
uniprot id: Q2LWJ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS06790
gene id: 56780:SYN_RS06790
uniprot id: Q2LT97
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

56780:SYN RS06220
gene id: 56780:SYN_RS06220
uniprot id: Q2LSY4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

56780:SYN RS14520
gene id: 56780:SYN_RS14520
uniprot id: Q2LY16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Cobalt importer (TC 3.A.1.18.1) family.
messages: Cell inner membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. Presumably responsible for energy coupling to the transport system.

56780:SYN RS02730
gene id: 56780:SYN_RS02730
uniprot id: Q2LQU4
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS08275
gene id: 56780:SYN_RS08275
uniprot id: Q2LU50
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

56780:SYN RS14320
gene id: 56780:SYN_RS14320
uniprot id: Q2LXW6
names: Similarity
messages: Belongs to the glutamate synthase family.

56780:SYN RS14725
gene id: 56780:SYN_RS14725
uniprot id: Q2LY59
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

56780:SYN RS11990
gene id: 56780:SYN_RS11990
uniprot id: Q2LWE9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

56780:SYN RS04875
gene id: 56780:SYN_RS04875
uniprot id: Q2LS56
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

56780:SYN RS04675
gene id: 56780:SYN_RS04675
uniprot id: Q2LS09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

56780:SYN RS09255
gene id: 56780:SYN_RS09255
uniprot id: Q2LUQ9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

56780:SYN RS01580
gene id: 56780:SYN_RS01580
uniprot id: Q2LQD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

56780:SYN RS01570
gene id: 56780:SYN_RS01570
uniprot id: Q2LQB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

56780:SYN RS07025
gene id: 56780:SYN_RS07025
uniprot id: Q2LTE7
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS05850
gene id: 56780:SYN_RS05850
uniprot id: Q2LSQ4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

56780:SYN RS08555
gene id: 56780:SYN_RS08555
uniprot id: Q2LUB2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

56780:SYN RS15070
gene id: 56780:SYN_RS15070
uniprot id: Q2LRH2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

56780:SYN RS10385
gene id: 56780:SYN_RS10385
uniprot id: Q2LVE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

56780:SYN RS03020
gene id: 56780:SYN_RS03020
uniprot id: Q2LR03
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

56780:SYN RS08970
gene id: 56780:SYN_RS08970
uniprot id: Q2LUJ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

56780:SYN RS00015
gene id: 56780:SYN_RS00015
uniprot id: Q2LYA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

56780:SYN RS10725
gene id: 56780:SYN_RS10725
uniprot id: Q2LVL9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS02815
gene id: 56780:SYN_RS02815
uniprot id: Q2LQV6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

56780:SYN RS09155
gene id: 56780:SYN_RS09155
uniprot id: Q2LUP0
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

56780:SYN RS13930
gene id: 56780:SYN_RS13930
uniprot id: Q2LXN1
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

56780:SYN RS08960
gene id: 56780:SYN_RS08960
uniprot id: Q2LUJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

56780:SYN RS04120
gene id: 56780:SYN_RS04120
uniprot id: Q2LRN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

56780:SYN RS07320
gene id: 56780:SYN_RS07320
uniprot id: Q2LTK3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

56780:SYN RS09745
gene id: 56780:SYN_RS09745
uniprot id: Q2LV07
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

56780:SYN RS03225
gene id: 56780:SYN_RS03225
uniprot id: Q2LR43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

56780:SYN RS02315
gene id: 56780:SYN_RS02315
uniprot id: Q2LPI7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

56780:SYN RS03220
gene id: 56780:SYN_RS03220
uniprot id: Q2LR45
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS03365
gene id: 56780:SYN_RS03365
uniprot id: Q2LR71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

56780:SYN RS06095
gene id: 56780:SYN_RS06095
uniprot id: Q2LSW0
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS06500
gene id: 56780:SYN_RS06500
uniprot id: Q2LT41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

56780:SYN RS06005
gene id: 56780:SYN_RS06005
uniprot id: Q2LSU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

56780:SYN RS00255
gene id: 56780:SYN_RS00255
uniprot id: Q2LPJ5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

56780:SYN RS08600
gene id: 56780:SYN_RS08600
uniprot id: Q2LUC1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

56780:SYN RS06330
gene id: 56780:SYN_RS06330
uniprot id: Q2LT08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

56780:SYN RS01595
gene id: 56780:SYN_RS01595
uniprot id: Q2LQC9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

56780:SYN RS03105
gene id: 56780:SYN_RS03105
uniprot id: Q2LR23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

56780:SYN RS03240
gene id: 56780:SYN_RS03240
uniprot id: Q2LR49
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS01565
gene id: 56780:SYN_RS01565
uniprot id: Q2LQB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

56780:SYN RS04415
gene id: 56780:SYN_RS04415
uniprot id: Q2LRV0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

56780:SYN RS07580
gene id: 56780:SYN_RS07580
uniprot id: Q2LTQ9
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

56780:SYN RS10445
gene id: 56780:SYN_RS10445
uniprot id: Q2LVG3
names: Similarity
messages: Belongs to the thioredoxin family.

56780:SYN RS06325
gene id: 56780:SYN_RS06325
uniprot id: Q2LT09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

56780:SYN RS12710
gene id: 56780:SYN_RS12710
uniprot id: Q2LWV6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS10525
gene id: 56780:SYN_RS10525
uniprot id: Q2LVI4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

56780:SYN RS01515
gene id: 56780:SYN_RS01515
uniprot id: Q2LQB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

56780:SYN RS10540
gene id: 56780:SYN_RS10540
uniprot id: Q2LVI1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

56780:SYN RS05915
gene id: 56780:SYN_RS05915
uniprot id: Q2LSR8
names: Similarity
messages: Belongs to the peptidase S49 family.

56780:SYN RS13360
gene id: 56780:SYN_RS13360
uniprot id: Q2LXA4
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS14250
gene id: 56780:SYN_RS14250
uniprot id: Q2LXV4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

56780:SYN RS11665
gene id: 56780:SYN_RS11665
uniprot id: Q2LW81
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

56780:SYN RS10305
gene id: 56780:SYN_RS10305
uniprot id: Q2LVD3
names: Similarity
messages: Belongs to the histone deacetylase family.

56780:SYN RS02770
gene id: 56780:SYN_RS02770
uniprot id: Q2LQU6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

56780:SYN RS04925
gene id: 56780:SYN_RS04925
uniprot id: Q2LS66
names: Similarity
messages: Belongs to the UPF0213 family.

56780:SYN RS09860
gene id: 56780:SYN_RS09860
uniprot id: Q2LV36
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

56780:SYN RS14085
gene id: 56780:SYN_RS14085
uniprot id: Q2LXR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

56780:SYN RS03935
gene id: 56780:SYN_RS03935
uniprot id: Q2LRK2
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

56780:SYN RS03265
gene id: 56780:SYN_RS03265
uniprot id: Q2LR54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

56780:SYN RS00350
gene id: 56780:SYN_RS00350
uniprot id: Q2LYC4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

56780:SYN RS01655
gene id: 56780:SYN_RS01655
uniprot id: Q2LPL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

56780:SYN RS04540
gene id: 56780:SYN_RS04540
uniprot id: Q2LRX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

56780:SYN RS13695
gene id: 56780:SYN_RS13695
uniprot id: Q2LXH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

56780:SYN RS08520
gene id: 56780:SYN_RS08520
uniprot id: Q2LUA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

56780:SYN RS09755
gene id: 56780:SYN_RS09755
uniprot id: Q2LV05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

56780:SYN RS08260
gene id: 56780:SYN_RS08260
uniprot id: Q2LU53
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

56780:SYN RS01490
gene id: 56780:SYN_RS01490
uniprot id: Q2LQ97
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

56780:SYN RS00490
gene id: 56780:SYN_RS00490
uniprot id: Q2LYI2
names: Similarity
messages: Belongs to the AOR/FOR family.

56780:SYN RS11520
gene id: 56780:SYN_RS11520
uniprot id: Q2LW46
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS04150
gene id: 56780:SYN_RS04150
uniprot id: Q2LRP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

56780:SYN RS13040
gene id: 56780:SYN_RS13040
uniprot id: Q2LX35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

56780:SYN RS06195
gene id: 56780:SYN_RS06195
uniprot id: Q2LSX9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

56780:SYN RS08510
gene id: 56780:SYN_RS08510
uniprot id: Q2LUA3
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

56780:SYN RS12925
gene id: 56780:SYN_RS12925
uniprot id: Q2LX12
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

56780:SYN RS11205
gene id: 56780:SYN_RS11205
uniprot id: Q2LVW9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

56780:SYN RS01510
gene id: 56780:SYN_RS01510
uniprot id: Q2LQB2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

56780:SYN RS14350
gene id: 56780:SYN_RS14350
uniprot id: Q2LXX4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS10550
gene id: 56780:SYN_RS10550
uniprot id: Q2LVI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

56780:SYN RS13645
gene id: 56780:SYN_RS13645
uniprot id: Q2LXH0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

56780:SYN RS01525
gene id: 56780:SYN_RS01525
uniprot id: Q2LQA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

56780:SYN RS03955
gene id: 56780:SYN_RS03955
uniprot id: Q2LRJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

56780:SYN RS00535
gene id: 56780:SYN_RS00535
uniprot id: Q2LQP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

56780:SYN RS06990
gene id: 56780:SYN_RS06990
uniprot id: Q2LTD5
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS01895
gene id: 56780:SYN_RS01895
uniprot id: Q2LPS7
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS09015
gene id: 56780:SYN_RS09015
uniprot id: Q2LUK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

56780:SYN RS14890
gene id: 56780:SYN_RS14890
uniprot id: Q2LPI2
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.

56780:SYN RS15210
gene id: 56780:SYN_RS15210
uniprot id: Q2LT04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

56780:SYN RS12575
gene id: 56780:SYN_RS12575
uniprot id: Q2LWS6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

56780:SYN RS02800
gene id: 56780:SYN_RS02800
uniprot id: Q2LQV0
names: Similarity
messages: Belongs to the peptidase S11 family.

56780:SYN RS01200
gene id: 56780:SYN_RS01200
uniprot id: Q2LQ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

56780:SYN RS03010
gene id: 56780:SYN_RS03010
uniprot id: Q2LR05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

56780:SYN RS11640
gene id: 56780:SYN_RS11640
uniprot id: Q2LW77
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

56780:SYN RS03850
gene id: 56780:SYN_RS03850
uniprot id: Q2LRI0
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS09020
gene id: 56780:SYN_RS09020
uniprot id: Q2LUK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

56780:SYN RS06140
gene id: 56780:SYN_RS06140
uniprot id: Q2LSW1
names: Similarity
messages: Belongs to the peptidase A24 family.

56780:SYN RS00260
gene id: 56780:SYN_RS00260
uniprot id: Q2LYH4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

56780:SYN RS09360
gene id: 56780:SYN_RS09360
uniprot id: Q2LUT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

56780:SYN RS09475
gene id: 56780:SYN_RS09475
uniprot id: Q2LUV8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

56780:SYN RS07215
gene id: 56780:SYN_RS07215
uniprot id: Q2LTJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

56780:SYN RS11090
gene id: 56780:SYN_RS11090
uniprot id: Q2LVU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

56780:SYN RS00270
gene id: 56780:SYN_RS00270
uniprot id: Q2LYH2
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS07100
gene id: 56780:SYN_RS07100
uniprot id: Q2LTF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

56780:SYN RS10700
gene id: 56780:SYN_RS10700
uniprot id: Q2LVL4
names: Similarity
messages: Belongs to the Skp family.

56780:SYN RS11390
gene id: 56780:SYN_RS11390
uniprot id: Q2LW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

56780:SYN RS06810
gene id: 56780:SYN_RS06810
uniprot id: Q2LTA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

56780:SYN RS03620
gene id: 56780:SYN_RS03620
uniprot id: Q2LRC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

56780:SYN RS03185
gene id: 56780:SYN_RS03185
uniprot id: Q2LR33
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

56780:SYN RS02710
gene id: 56780:SYN_RS02710
uniprot id: Q2LQT9
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS05655
gene id: 56780:SYN_RS05655
uniprot id: Q2LSL9
names: Similarity
messages: Belongs to the MotB family.

56780:SYN RS03465
gene id: 56780:SYN_RS03465
uniprot id: Q2LR94
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

56780:SYN RS09365
gene id: 56780:SYN_RS09365
uniprot id: Q2LUT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

56780:SYN RS04790
gene id: 56780:SYN_RS04790
uniprot id: Q2LS35
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

56780:SYN RS09940
gene id: 56780:SYN_RS09940
uniprot id: Q2LV55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

56780:SYN RS01500
gene id: 56780:SYN_RS01500
uniprot id: Q2LQ95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

56780:SYN RS01420
gene id: 56780:SYN_RS01420
uniprot id: Q2LQ92
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

56780:SYN RS07965
gene id: 56780:SYN_RS07965
uniprot id: Q2LTY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm

56780:SYN RS10530
gene id: 56780:SYN_RS10530
uniprot id: Q2LVI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

56780:SYN RS01995
gene id: 56780:SYN_RS01995
uniprot id: Q2LPU8
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS14175
gene id: 56780:SYN_RS14175
uniprot id: Q2LXT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

56780:SYN RS14840
gene id: 56780:SYN_RS14840
uniprot id: Q2LY87
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

56780:SYN RS02755
gene id: 56780:SYN_RS02755
uniprot id: Q2LQU9
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS07395
gene id: 56780:SYN_RS07395
uniprot id: Q2LTM3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS04605
gene id: 56780:SYN_RS04605
uniprot id: Q2LRZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

56780:SYN RS10240
gene id: 56780:SYN_RS10240
uniprot id: Q2LVB3
names: Similarity
messages: Belongs to the universal stress protein A family.

56780:SYN RS01590
gene id: 56780:SYN_RS01590
uniprot id: Q2LQD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

56780:SYN RS10680
gene id: 56780:SYN_RS10680
uniprot id: Q2LVL8
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

56780:SYN RS06175
gene id: 56780:SYN_RS06175
uniprot id: Q2LSX5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

56780:SYN RS11710
gene id: 56780:SYN_RS11710
uniprot id: Q2LW88
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

56780:SYN RS11075
gene id: 56780:SYN_RS11075
uniprot id: Q2LVU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

56780:SYN RS08615
gene id: 56780:SYN_RS08615
uniprot id: Q2LUC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

56780:SYN RS05185
gene id: 56780:SYN_RS05185
uniprot id: Q2LSB6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

56780:SYN RS01450
gene id: 56780:SYN_RS01450
uniprot id: Q2LQ86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

56780:SYN RS03170
gene id: 56780:SYN_RS03170
uniprot id: Q2LR37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

56780:SYN RS00885
gene id: 56780:SYN_RS00885
uniprot id: Q2LQM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

56780:SYN RS05375
gene id: 56780:SYN_RS05375
uniprot id: Q2LSF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

56780:SYN RS12905
gene id: 56780:SYN_RS12905
uniprot id: Q2LX06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

56780:SYN RS07115
gene id: 56780:SYN_RS07115
uniprot id: Q2LTG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

56780:SYN RS09630
gene id: 56780:SYN_RS09630
uniprot id: Q2LUY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

56780:SYN RS03125
gene id: 56780:SYN_RS03125
uniprot id: Q2LR20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

56780:SYN RS04600
gene id: 56780:SYN_RS04600
uniprot id: Q2LRY7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

56780:SYN RS06260
gene id: 56780:SYN_RS06260
uniprot id: Q2LSY6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

56780:SYN RS07565
gene id: 56780:SYN_RS07565
uniprot id: Q2LTQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

56780:SYN RS09265
gene id: 56780:SYN_RS09265
uniprot id: Q2LUQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

56780:SYN RS05830
gene id: 56780:SYN_RS05830
uniprot id: Q2LSP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

56780:SYN RS03060
gene id: 56780:SYN_RS03060
uniprot id: Q2LR07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

56780:SYN RS06710
gene id: 56780:SYN_RS06710
uniprot id: Q2LT83
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

56780:SYN RS09965
gene id: 56780:SYN_RS09965
uniprot id: Q2LV56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

56780:SYN RS10555
gene id: 56780:SYN_RS10555
uniprot id: Q2LVI8
names: Similarity
messages: Belongs to the universal stress protein A family.

56780:SYN RS14835
gene id: 56780:SYN_RS14835
uniprot id: Q2LY80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

56780:SYN RS01625
gene id: 56780:SYN_RS01625
uniprot id: Q2LPM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

56780:SYN RS08690
gene id: 56780:SYN_RS08690
uniprot id: Q2LUE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

56780:SYN RS10190
gene id: 56780:SYN_RS10190
uniprot id: Q2LVA3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

56780:SYN RS01315
gene id: 56780:SYN_RS01315
uniprot id: Q2LQ68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

56780:SYN RS00595
gene id: 56780:SYN_RS00595
uniprot id: Q2LYD8
names: Subcellular Location Annotation
messages: Periplasm

56780:SYN RS05600
gene id: 56780:SYN_RS05600
uniprot id: Q2LSK6
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS01480
gene id: 56780:SYN_RS01480
uniprot id: Q2LQ99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

56780:SYN RS03210
gene id: 56780:SYN_RS03210
uniprot id: Q2LR38
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS06435
gene id: 56780:SYN_RS06435
uniprot id: Q2LT33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

56780:SYN RS02735
gene id: 56780:SYN_RS02735
uniprot id: Q2LQU3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

56780:SYN RS07310
gene id: 56780:SYN_RS07310
uniprot id: Q2LTK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

56780:SYN RS06785
gene id: 56780:SYN_RS06785
uniprot id: Q2LT98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

56780:SYN RS11855
gene id: 56780:SYN_RS11855
uniprot id: Q2LWC2
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS07380
gene id: 56780:SYN_RS07380
uniprot id: Q2LTL7
names: Similarity
messages: Belongs to the peptidase M16 family.

56780:SYN RS07305
gene id: 56780:SYN_RS07305
uniprot id: Q2LTK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

56780:SYN RS05290
gene id: 56780:SYN_RS05290
uniprot id: Q2LSD7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

56780:SYN RS14505
gene id: 56780:SYN_RS14505
uniprot id: Q2LY09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

56780:SYN RS01485
gene id: 56780:SYN_RS01485
uniprot id: Q2LQ98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

56780:SYN RS10600
gene id: 56780:SYN_RS10600
uniprot id: Q2LVJ7
names: Similarity
messages: Belongs to the GSP E family.

56780:SYN RS00840
gene id: 56780:SYN_RS00840
uniprot id: Q2LQK9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

56780:SYN RS01460
gene id: 56780:SYN_RS01460
uniprot id: Q2LQA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

56780:SYN RS04890
gene id: 56780:SYN_RS04890
uniprot id: Q2LS53
names: Similarity
messages: Belongs to the UPF0111 family.

56780:SYN RS08395
gene id: 56780:SYN_RS08395
uniprot id: Q2LU72
names: Similarity
messages: Belongs to the UPF0045 family.

56780:SYN RS10595
gene id: 56780:SYN_RS10595
uniprot id: Q2LVJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

56780:SYN RS06335
gene id: 56780:SYN_RS06335
uniprot id: Q2LT07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

56780:SYN RS13875
gene id: 56780:SYN_RS13875
uniprot id: Q2LXL5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

56780:SYN RS05825
gene id: 56780:SYN_RS05825
uniprot id: Q2LSP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

56780:SYN RS14415
gene id: 56780:SYN_RS14415
uniprot id: Q2LXZ2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

56780:SYN RS07685
gene id: 56780:SYN_RS07685
uniprot id: Q2LTT4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

56780:SYN RS13985
gene id: 56780:SYN_RS13985
uniprot id: Q2LXP7
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

56780:SYN RS12495
gene id: 56780:SYN_RS12495
uniprot id: Q2LWQ4
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

56780:SYN RS06460
gene id: 56780:SYN_RS06460
uniprot id: Q2LT38
names: Similarity
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.

56780:SYN RS13600
gene id: 56780:SYN_RS13600
uniprot id: Q2LXF3
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS07595
gene id: 56780:SYN_RS07595
uniprot id: Q2LTR6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

56780:SYN RS11160
gene id: 56780:SYN_RS11160
uniprot id: Q2LVW1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

56780:SYN RS01685
gene id: 56780:SYN_RS01685
uniprot id: Q2LPN0
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

56780:SYN RS06580
gene id: 56780:SYN_RS06580
uniprot id: Q2LT54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

56780:SYN RS11095
gene id: 56780:SYN_RS11095
uniprot id: Q2LVU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

56780:SYN RS00215
gene id: 56780:SYN_RS00215
uniprot id: Q2LQJ6
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS12670
gene id: 56780:SYN_RS12670
uniprot id: Q2LWU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

56780:SYN RS08695
gene id: 56780:SYN_RS08695
uniprot id: Q2LUD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

56780:SYN RS12190
gene id: 56780:SYN_RS12190
uniprot id: Q2LWJ5
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

56780:SYN RS05685
gene id: 56780:SYN_RS05685
uniprot id: Q2LSM2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

56780:SYN RS10795
gene id: 56780:SYN_RS10795
uniprot id: Q2LVN5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

56780:SYN RS07015
gene id: 56780:SYN_RS07015
uniprot id: Q2LTE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

56780:SYN RS04230
gene id: 56780:SYN_RS04230
uniprot id: Q2LRR5
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

56780:SYN RS12095
gene id: 56780:SYN_RS12095
uniprot id: Q2LWH5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

56780:SYN RS02160
gene id: 56780:SYN_RS02160
uniprot id: Q2LPY6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

56780:SYN RS14095
gene id: 56780:SYN_RS14095
uniprot id: Q2LXS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

56780:SYN RS11230
gene id: 56780:SYN_RS11230
uniprot id: Q2LVX9
names: Similarity
messages: Belongs to the HupF/HypC family.

56780:SYN RS02995
gene id: 56780:SYN_RS02995
uniprot id: Q2LQZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

56780:SYN RS01360
gene id: 56780:SYN_RS01360
uniprot id: Q2LQ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

56780:SYN RS00615
gene id: 56780:SYN_RS00615
uniprot id: Q2LYD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

56780:SYN RS14130
gene id: 56780:SYN_RS14130
uniprot id: Q2LXS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity.

56780:SYN RS15170
gene id: 56780:SYN_RS15170
uniprot id: Q2LSJ8
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS03385
gene id: 56780:SYN_RS03385
uniprot id: Q2LR76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

56780:SYN RS12890
gene id: 56780:SYN_RS12890
uniprot id: Q2LWZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

56780:SYN RS15315
gene id: 56780:SYN_RS15315
uniprot id: Q2LUE4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

56780:SYN RS08900
gene id: 56780:SYN_RS08900
uniprot id: Q2LUI3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

56780:SYN RS04550
gene id: 56780:SYN_RS04550
uniprot id: Q2LRX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

56780:SYN RS13430
gene id: 56780:SYN_RS13430
uniprot id: Q2LXC1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

56780:SYN RS09540
gene id: 56780:SYN_RS09540
uniprot id: Q2LUW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

56780:SYN RS09900
gene id: 56780:SYN_RS09900
uniprot id: Q2LV45
names: Similarity
messages: Belongs to the group II decarboxylase family.

56780:SYN RS13740
gene id: 56780:SYN_RS13740
uniprot id: Q2LXI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

56780:SYN RS05330
gene id: 56780:SYN_RS05330
uniprot id: Q2LSE8
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS13000
gene id: 56780:SYN_RS13000
uniprot id: Q2LX24
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

56780:SYN RS08700
gene id: 56780:SYN_RS08700
uniprot id: Q2LUD8
names: Similarity
messages: Belongs to the TrpF family.

56780:SYN RS12595
gene id: 56780:SYN_RS12595
uniprot id: Q2LWT2
names: Similarity
messages: Belongs to the bacterial secretin family.

56780:SYN RS00250
gene id: 56780:SYN_RS00250
uniprot id: Q2LPJ6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

56780:SYN RS02980
gene id: 56780:SYN_RS02980
uniprot id: Q2LQZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

56780:SYN RS03145
gene id: 56780:SYN_RS03145
uniprot id: Q2LR25
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

56780:SYN RS01080
gene id: 56780:SYN_RS01080
uniprot id: Q2LQP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Homotetramer.
messages: Mediates the conversion of cyclohexane-1-carbonyl-CoA into cyclohex-1-ene-1-carbonyl-CoA in biosynthesis of cyclohexane-1-carboxylate, a by-product produced during fermentation of benzoate and crotonate to acetate.

56780:SYN RS12715
gene id: 56780:SYN_RS12715
uniprot id: Q2LWV5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

56780:SYN RS02930
gene id: 56780:SYN_RS02930
uniprot id: Q2LQY3
names: Similarity
messages: Belongs to the CapA family.

56780:SYN RS10490
gene id: 56780:SYN_RS10490
uniprot id: Q2LVH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

56780:SYN RS14215
gene id: 56780:SYN_RS14215
uniprot id: Q2LXU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Homohexamer.
messages: Involved in the central benzoyl-CoA catabolism. Catalyzes the addition of one molecule of water to the double bond and the hydrolytic cleavage of C-C bond in the alicyclic ring, 6-oxocyclohex-1-ene-1-carbonyl-CoA (6-OCH-CoA) to yield 3-hydroxypimelyl-CoA.

56780:SYN RS06775
gene id: 56780:SYN_RS06775
uniprot id: Q2LT95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

56780:SYN RS01835
gene id: 56780:SYN_RS01835
uniprot id: Q2LPR7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

56780:SYN RS08455
gene id: 56780:SYN_RS08455
uniprot id: Q2LU86
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

56780:SYN RS07550
gene id: 56780:SYN_RS07550
uniprot id: Q2LTQ7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

56780:SYN RS12200
gene id: 56780:SYN_RS12200
uniprot id: Q2LWJ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS09865
gene id: 56780:SYN_RS09865
uniprot id: Q2LV35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

56780:SYN RS14220
gene id: 56780:SYN_RS14220
uniprot id: Q2LXU6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

56780:SYN RS12515
gene id: 56780:SYN_RS12515
uniprot id: Q2LWR0
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

56780:SYN RS00020
gene id: 56780:SYN_RS00020
uniprot id: Q2LYA1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

56780:SYN RS07140
gene id: 56780:SYN_RS07140
uniprot id: Q2LTG9
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS02925
gene id: 56780:SYN_RS02925
uniprot id: Q2LQY4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS07635
gene id: 56780:SYN_RS07635
uniprot id: Q2LTR7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

56780:SYN RS11165
gene id: 56780:SYN_RS11165
uniprot id: Q2LVW8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

56780:SYN RS02740
gene id: 56780:SYN_RS02740
uniprot id: Q2LQU2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

56780:SYN RS05240
gene id: 56780:SYN_RS05240
uniprot id: Q2LSC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

56780:SYN RS08730
gene id: 56780:SYN_RS08730
uniprot id: Q2LUE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

56780:SYN RS01505
gene id: 56780:SYN_RS01505
uniprot id: Q2LQB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

56780:SYN RS06605
gene id: 56780:SYN_RS06605
uniprot id: Q2LT59
names: Similarity
messages: Belongs to the AOR/FOR family.

56780:SYN RS14345
gene id: 56780:SYN_RS14345
uniprot id: Q2LXX0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS00125
gene id: 56780:SYN_RS00125
uniprot id: Q2LYB5
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS13255
gene id: 56780:SYN_RS13255
uniprot id: Q2LX87
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

56780:SYN RS13280
gene id: 56780:SYN_RS13280
uniprot id: Q2LX93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

56780:SYN RS12170
gene id: 56780:SYN_RS12170
uniprot id: Q2LWJ0
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

56780:SYN RS08205
gene id: 56780:SYN_RS08205
uniprot id: Q2LU35
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

56780:SYN RS02895
gene id: 56780:SYN_RS02895
uniprot id: Q2LQY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

56780:SYN RS06130
gene id: 56780:SYN_RS06130
uniprot id: Q2LSW3
names: Similarity
messages: Belongs to the bacterial secretin family.

56780:SYN RS04220
gene id: 56780:SYN_RS04220
uniprot id: Q2LRQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

56780:SYN RS13725
gene id: 56780:SYN_RS13725
uniprot id: Q2LXI2
names: Similarity
messages: Belongs to the peptidase S24 family.

56780:SYN RS04590
gene id: 56780:SYN_RS04590
uniprot id: Q2LRY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

56780:SYN RS03735
gene id: 56780:SYN_RS03735
uniprot id: Q2LRF4
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

56780:SYN RS07625
gene id: 56780:SYN_RS07625
uniprot id: Q2LTR9
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

56780:SYN RS08765
gene id: 56780:SYN_RS08765
uniprot id: Q2LUF3
names: Similarity
messages: Belongs to the UPF0047 family.

56780:SYN RS12900
gene id: 56780:SYN_RS12900
uniprot id: Q2LX07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

56780:SYN RS11050
gene id: 56780:SYN_RS11050
uniprot id: Q2LVT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

56780:SYN RS01195
gene id: 56780:SYN_RS01195
uniprot id: Q2LQ43
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

56780:SYN RS12360
gene id: 56780:SYN_RS12360
uniprot id: Q2LWM8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

56780:SYN RS06780
gene id: 56780:SYN_RS06780
uniprot id: Q2LT99
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

56780:SYN RS06795
gene id: 56780:SYN_RS06795
uniprot id: Q2LT96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

56780:SYN RS09200
gene id: 56780:SYN_RS09200
uniprot id: Q2LUP3
names: Similarity
messages: Belongs to the histone deacetylase family.

56780:SYN RS03130
gene id: 56780:SYN_RS03130
uniprot id: Q2LR24
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

56780:SYN RS03375
gene id: 56780:SYN_RS03375
uniprot id: Q2LR78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

56780:SYN RS13120
gene id: 56780:SYN_RS13120
uniprot id: Q2LX55
names: Similarity
messages: Belongs to the disproportionating enzyme family.

56780:SYN RS11135
gene id: 56780:SYN_RS11135
uniprot id: Q2LVV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

56780:SYN RS12490
gene id: 56780:SYN_RS12490
uniprot id: Q2LWQ5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

56780:SYN RS14825
gene id: 56780:SYN_RS14825
uniprot id: Q2LY82
names: Subunit
messages: Heterodimer of a large and a small subunit.

56780:SYN RS03540
gene id: 56780:SYN_RS03540
uniprot id: Q2LRA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

56780:SYN RS13590
gene id: 56780:SYN_RS13590
uniprot id: Q2LXF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

56780:SYN RS08890
gene id: 56780:SYN_RS08890
uniprot id: Q2LUI0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

56780:SYN RS07370
gene id: 56780:SYN_RS07370
uniprot id: Q2LTL1
names: Similarity
messages: Belongs to the peptidase M20A family.

56780:SYN RS15470
gene id: 56780:SYN_RS15470
uniprot id: Q2LWW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

56780:SYN RS04175
gene id: 56780:SYN_RS04175
uniprot id: Q2LRQ0
names: Similarity
messages: Belongs to the peptidase S41A family.

56780:SYN RS12510
gene id: 56780:SYN_RS12510
uniprot id: Q2LWR1
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS09055
gene id: 56780:SYN_RS09055
uniprot id: Q2LUL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

56780:SYN RS07615
gene id: 56780:SYN_RS07615
uniprot id: Q2LTS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

56780:SYN RS11185
gene id: 56780:SYN_RS11185
uniprot id: Q2LVX3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS06465
gene id: 56780:SYN_RS06465
uniprot id: Q2LT37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

56780:SYN RS07110
gene id: 56780:SYN_RS07110
uniprot id: Q2LTG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

56780:SYN RS03075
gene id: 56780:SYN_RS03075
uniprot id: Q2LR13
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

56780:SYN RS00820
gene id: 56780:SYN_RS00820
uniprot id: Q2LQG2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

56780:SYN RS15025
gene id: 56780:SYN_RS15025
uniprot id: Q2LR59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

56780:SYN RS03570
gene id: 56780:SYN_RS03570
uniprot id: Q2LRB5
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

56780:SYN RS06815
gene id: 56780:SYN_RS06815
uniprot id: Q2LTA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

56780:SYN RS12380
gene id: 56780:SYN_RS12380
uniprot id: Q2LWN2
names: Similarity
messages: Belongs to the asparagine synthetase family.

56780:SYN RS10660
gene id: 56780:SYN_RS10660
uniprot id: Q2LVL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

56780:SYN RS00925
gene id: 56780:SYN_RS00925
uniprot id: Q2LQN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

56780:SYN RS08845
gene id: 56780:SYN_RS08845
uniprot id: Q2LUH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.

56780:SYN RS04520
gene id: 56780:SYN_RS04520
uniprot id: Q2LRX2
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

56780:SYN RS04545
gene id: 56780:SYN_RS04545
uniprot id: Q2LRX7
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS01780
gene id: 56780:SYN_RS01780
uniprot id: Q2LPQ6
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

56780:SYN RS13990
gene id: 56780:SYN_RS13990
uniprot id: Q2LXP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

56780:SYN RS15220
gene id: 56780:SYN_RS15220
uniprot id: Q2LT27
names: Similarity
messages: Belongs to the FlgM family.

56780:SYN RS05045
gene id: 56780:SYN_RS05045
uniprot id: Q2LS89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

56780:SYN RS00390
gene id: 56780:SYN_RS00390
uniprot id: Q2LYB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

56780:SYN RS13555
gene id: 56780:SYN_RS13555
uniprot id: Q2LXE3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

56780:SYN RS06105
gene id: 56780:SYN_RS06105
uniprot id: Q2LSV8
names: Similarity
messages: Belongs to the GSP E family.

56780:SYN RS03205
gene id: 56780:SYN_RS03205
uniprot id: Q2LR39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

56780:SYN RS00835
gene id: 56780:SYN_RS00835
uniprot id: Q2LQL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

56780:SYN RS01670
gene id: 56780:SYN_RS01670
uniprot id: Q2LPL3
names: Similarity
messages: Belongs to the CinA family.

56780:SYN RS15415
gene id: 56780:SYN_RS15415
uniprot id: Q2LW85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

56780:SYN RS12845
gene id: 56780:SYN_RS12845
uniprot id: Q2LWY2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

56780:SYN RS12160
gene id: 56780:SYN_RS12160
uniprot id: Q2LWJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

56780:SYN RS10425
gene id: 56780:SYN_RS10425
uniprot id: Q2LVG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

56780:SYN RS11880
gene id: 56780:SYN_RS11880
uniprot id: Q2LWC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

56780:SYN RS13675
gene id: 56780:SYN_RS13675
uniprot id: Q2LXH3
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

56780:SYN RS02795
gene id: 56780:SYN_RS02795
uniprot id: Q2LQV1
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

56780:SYN RS12040
gene id: 56780:SYN_RS12040
uniprot id: Q2LWF9
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS11270
gene id: 56780:SYN_RS11270
uniprot id: Q2LVY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

56780:SYN RS13950
gene id: 56780:SYN_RS13950
uniprot id: Q2LXN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

56780:SYN RS03270
gene id: 56780:SYN_RS03270
uniprot id: Q2LR53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

56780:SYN RS08785
gene id: 56780:SYN_RS08785
uniprot id: Q2LUF9
names: Similarity
messages: Belongs to the peptidase S66 family.

56780:SYN RS14870
gene id: 56780:SYN_RS14870
uniprot id: Q2LYD2
names: Similarity
messages: Belongs to the SecB family.

56780:SYN RS13565
gene id: 56780:SYN_RS13565
uniprot id: Q2LXF1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

56780:SYN RS10655
gene id: 56780:SYN_RS10655
uniprot id: Q2LVK5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS10330
gene id: 56780:SYN_RS10330
uniprot id: Q2LVD6
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS01465
gene id: 56780:SYN_RS01465
uniprot id: Q2LQA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

56780:SYN RS06805
gene id: 56780:SYN_RS06805
uniprot id: Q2LTA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

56780:SYN RS01585
gene id: 56780:SYN_RS01585
uniprot id: Q2LQD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

56780:SYN RS13055
gene id: 56780:SYN_RS13055
uniprot id: Q2LX41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

56780:SYN RS00240
gene id: 56780:SYN_RS00240
uniprot id: Q2LPJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

56780:SYN RS11470
gene id: 56780:SYN_RS11470
uniprot id: Q2LW33
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

56780:SYN RS11200
gene id: 56780:SYN_RS11200
uniprot id: Q2LVX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

56780:SYN RS03670
gene id: 56780:SYN_RS03670
uniprot id: Q2LRE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

56780:SYN RS11570
gene id: 56780:SYN_RS11570
uniprot id: Q2LW61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

56780:SYN RS00665
gene id: 56780:SYN_RS00665
uniprot id: Q2LPK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

56780:SYN RS00915
gene id: 56780:SYN_RS00915
uniprot id: Q2LQM2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

56780:SYN RS13045
gene id: 56780:SYN_RS13045
uniprot id: Q2LX34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

56780:SYN RS05960
gene id: 56780:SYN_RS05960
uniprot id: Q2LSS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

56780:SYN RS14245
gene id: 56780:SYN_RS14245
uniprot id: Q2LXV5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

56780:SYN RS14525
gene id: 56780:SYN_RS14525
uniprot id: Q2LY15
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS12665
gene id: 56780:SYN_RS12665
uniprot id: Q2LWU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

56780:SYN RS06900
gene id: 56780:SYN_RS06900
uniprot id: Q2LTB7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.

56780:SYN RS11800
gene id: 56780:SYN_RS11800
uniprot id: Q2LWA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

56780:SYN RS01325
gene id: 56780:SYN_RS01325
uniprot id: Q2LQ66
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

56780:SYN RS09660
gene id: 56780:SYN_RS09660
uniprot id: Q2LUZ4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

56780:SYN RS07220
gene id: 56780:SYN_RS07220
uniprot id: Q2LTI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

56780:SYN RS01550
gene id: 56780:SYN_RS01550
uniprot id: Q2LQC0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

56780:SYN RS00895
gene id: 56780:SYN_RS00895
uniprot id: Q2LQM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

56780:SYN RS05970
gene id: 56780:SYN_RS05970
uniprot id: Q2LSS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

56780:SYN RS12765
gene id: 56780:SYN_RS12765
uniprot id: Q2LWW2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

56780:SYN RS00570
gene id: 56780:SYN_RS00570
uniprot id: Q2LYF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

56780:SYN RS03600
gene id: 56780:SYN_RS03600
uniprot id: Q2LRC1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

56780:SYN RS14625
gene id: 56780:SYN_RS14625
uniprot id: Q2LY33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

56780:SYN RS06425
gene id: 56780:SYN_RS06425
uniprot id: Q2LT25
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

56780:SYN RS13715
gene id: 56780:SYN_RS13715
uniprot id: Q2LXI4
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS13575
gene id: 56780:SYN_RS13575
uniprot id: Q2LXE8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

56780:SYN RS01930
gene id: 56780:SYN_RS01930
uniprot id: Q2LPU1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

56780:SYN RS03230
gene id: 56780:SYN_RS03230
uniprot id: Q2LR51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

56780:SYN RS12550
gene id: 56780:SYN_RS12550
uniprot id: Q2LWS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

56780:SYN RS12165
gene id: 56780:SYN_RS12165
uniprot id: Q2LWJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

56780:SYN RS08720
gene id: 56780:SYN_RS08720
uniprot id: Q2LUE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

56780:SYN RS14050
gene id: 56780:SYN_RS14050
uniprot id: Q2LXR1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

56780:SYN RS05390
gene id: 56780:SYN_RS05390
uniprot id: Q2LSG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

56780:SYN RS04495
gene id: 56780:SYN_RS04495
uniprot id: Q2LRW7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

56780:SYN RS00245
gene id: 56780:SYN_RS00245
uniprot id: Q2LPJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

56780:SYN RS00845
gene id: 56780:SYN_RS00845
uniprot id: Q2LQK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

56780:SYN RS10940
gene id: 56780:SYN_RS10940
uniprot id: Q2LVR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

56780:SYN RS13745
gene id: 56780:SYN_RS13745
uniprot id: Q2LXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

56780:SYN RS06315
gene id: 56780:SYN_RS06315
uniprot id: Q2LT01
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

56780:SYN RS00385
gene id: 56780:SYN_RS00385
uniprot id: Q2LYB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

56780:SYN RS14530
gene id: 56780:SYN_RS14530
uniprot id: Q2LY14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

56780:SYN RS01285
gene id: 56780:SYN_RS01285
uniprot id: Q2LQ50
names: Similarity
messages: Belongs to the MlaA family.

56780:SYN RS01435
gene id: 56780:SYN_RS01435
uniprot id: Q2LQ89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

56780:SYN RS08290
gene id: 56780:SYN_RS08290
uniprot id: Q2LU57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

56780:SYN RS01665
gene id: 56780:SYN_RS01665
uniprot id: Q2LPL4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

56780:SYN RS08680
gene id: 56780:SYN_RS08680
uniprot id: Q2LUD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

56780:SYN RS05610
gene id: 56780:SYN_RS05610
uniprot id: Q2LSK9
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

56780:SYN RS03135
gene id: 56780:SYN_RS03135
uniprot id: Q2LR28
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

56780:SYN RS09905
gene id: 56780:SYN_RS09905
uniprot id: Q2LV44
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

56780:SYN RS10480
gene id: 56780:SYN_RS10480
uniprot id: Q2LVH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

56780:SYN RS12830
gene id: 56780:SYN_RS12830
uniprot id: Q2LWY5
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

56780:SYN RS02360
gene id: 56780:SYN_RS02360
uniprot id: Q2LQL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

56780:SYN RS00515
gene id: 56780:SYN_RS00515
uniprot id: Q2LYH6
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

56780:SYN RS05815
gene id: 56780:SYN_RS05815
uniprot id: Q2LSQ1
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

56780:SYN RS09290
gene id: 56780:SYN_RS09290
uniprot id: Q2LUR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

56780:SYN RS10690
gene id: 56780:SYN_RS10690
uniprot id: Q2LVL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

56780:SYN RS13975
gene id: 56780:SYN_RS13975
uniprot id: Q2LXN9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

56780:SYN RS03650
gene id: 56780:SYN_RS03650
uniprot id: Q2LRD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

56780:SYN RS05875
gene id: 56780:SYN_RS05875
uniprot id: Q2LSQ7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

56780:SYN RS06505
gene id: 56780:SYN_RS06505
uniprot id: Q2LT40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

56780:SYN RS07505
gene id: 56780:SYN_RS07505
uniprot id: Q2LTP2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

56780:SYN RS05535
gene id: 56780:SYN_RS05535
uniprot id: Q2LSI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

56780:SYN RS04650
gene id: 56780:SYN_RS04650
uniprot id: Q2LRZ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

56780:SYN RS02865
gene id: 56780:SYN_RS02865
uniprot id: Q2LQW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

56780:SYN RS04235
gene id: 56780:SYN_RS04235
uniprot id: Q2LRR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

56780:SYN RS09535
gene id: 56780:SYN_RS09535
uniprot id: Q2LUW6
names: Similarity
messages: Belongs to the GSP E family.

56780:SYN RS02275
gene id: 56780:SYN_RS02275
uniprot id: Q2LQ04
names: Similarity
messages: Belongs to the AOR/FOR family.

56780:SYN RS11980
gene id: 56780:SYN_RS11980
uniprot id: Q2LWF1
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

56780:SYN RS02065
gene id: 56780:SYN_RS02065
uniprot id: Q2LPV8
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS09280
gene id: 56780:SYN_RS09280
uniprot id: Q2LUR2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

56780:SYN RS04625
gene id: 56780:SYN_RS04625
uniprot id: Q2LRZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

56780:SYN RS12720
gene id: 56780:SYN_RS12720
uniprot id: Q2LWV4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

56780:SYN RS01430
gene id: 56780:SYN_RS01430
uniprot id: Q2LQ90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

56780:SYN RS13605
gene id: 56780:SYN_RS13605
uniprot id: Q2LXF8
names: Subcellular Location Annotation
messages: Membrane

56780:SYN RS10710
gene id: 56780:SYN_RS10710
uniprot id: Q2LVM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

56780:SYN RS06970
gene id: 56780:SYN_RS06970
uniprot id: Q2LTD9
names: Similarity
messages: Belongs to the universal stress protein A family.

56780:SYN RS06395
gene id: 56780:SYN_RS06395
uniprot id: Q2LT23
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

56780:SYN RS14635
gene id: 56780:SYN_RS14635
uniprot id: Q2LY40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

56780:SYN RS01660
gene id: 56780:SYN_RS01660
uniprot id: Q2LPL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

56780:SYN RS05780
gene id: 56780:SYN_RS05780
uniprot id: Q2LSP1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

56780:SYN RS12435
gene id: 56780:SYN_RS12435
uniprot id: Q2LWP8
names: Function
names: Similarity
messages: Belongs to the rhamnosyl O-methyltransferase family.
messages: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).

56780:SYN RS06835
gene id: 56780:SYN_RS06835
uniprot id: Q2LTA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

56780:SYN RS05065
gene id: 56780:SYN_RS05065
uniprot id: Q2LS91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell inner membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

56780:SYN RS03380
gene id: 56780:SYN_RS03380
uniprot id: Q2LR77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.