563040:SAUT RS01165
gene id: 563040:SAUT_RS01165
uniprot id: E0UTQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

563040:SAUT RS10715
gene id: 563040:SAUT_RS10715
uniprot id: E0US67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

563040:SAUT RS02645
gene id: 563040:SAUT_RS02645
uniprot id: E0UPB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

563040:SAUT RS04805
gene id: 563040:SAUT_RS04805
uniprot id: E0URP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.
messages: Cytoplasm

563040:SAUT RS02175
gene id: 563040:SAUT_RS02175
uniprot id: E0UUX0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

563040:SAUT RS00505
gene id: 563040:SAUT_RS00505
uniprot id: E0USX3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

563040:SAUT RS07205
gene id: 563040:SAUT_RS07205
uniprot id: E0UU97
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

563040:SAUT RS10655
gene id: 563040:SAUT_RS10655
uniprot id: E0URY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

563040:SAUT RS02840
gene id: 563040:SAUT_RS02840
uniprot id: E0UPM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

563040:SAUT RS00345
gene id: 563040:SAUT_RS00345
uniprot id: E0UST8
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS05745
gene id: 563040:SAUT_RS05745
uniprot id: E0USL1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

563040:SAUT RS05645
gene id: 563040:SAUT_RS05645
uniprot id: E0USJ2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

563040:SAUT RS10425
gene id: 563040:SAUT_RS10425
uniprot id: E0URT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

563040:SAUT RS10920
gene id: 563040:SAUT_RS10920
uniprot id: E0USA5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

563040:SAUT RS05685
gene id: 563040:SAUT_RS05685
uniprot id: E0USK0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

563040:SAUT RS01325
gene id: 563040:SAUT_RS01325
uniprot id: E0UU07
names: Similarity
messages: Belongs to the GSP E family.

563040:SAUT RS08015
gene id: 563040:SAUT_RS08015
uniprot id: E0UV47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

563040:SAUT RS05840
gene id: 563040:SAUT_RS05840
uniprot id: E0USN0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

563040:SAUT RS00225
gene id: 563040:SAUT_RS00225
uniprot id: E0USR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

563040:SAUT RS03895
gene id: 563040:SAUT_RS03895
uniprot id: E0UQT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

563040:SAUT RS10000
gene id: 563040:SAUT_RS10000
uniprot id: E0URD2
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS09305
gene id: 563040:SAUT_RS09305
uniprot id: E0UQK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

563040:SAUT RS10645
gene id: 563040:SAUT_RS10645
uniprot id: E0URY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

563040:SAUT RS09705
gene id: 563040:SAUT_RS09705
uniprot id: E0UR03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

563040:SAUT RS09985
gene id: 563040:SAUT_RS09985
uniprot id: E0URC9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

563040:SAUT RS07280
gene id: 563040:SAUT_RS07280
uniprot id: E0UUB2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

563040:SAUT RS02460
gene id: 563040:SAUT_RS02460
uniprot id: E0UP76
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS00285
gene id: 563040:SAUT_RS00285
uniprot id: E0USS8
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

563040:SAUT RS01315
gene id: 563040:SAUT_RS01315
uniprot id: E0UU05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

563040:SAUT RS07145
gene id: 563040:SAUT_RS07145
uniprot id: E0UU86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

563040:SAUT RS08980
gene id: 563040:SAUT_RS08980
uniprot id: E0UQ70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

563040:SAUT RS06520
gene id: 563040:SAUT_RS06520
uniprot id: E0UTH0
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS02660
gene id: 563040:SAUT_RS02660
uniprot id: E0UPB6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

563040:SAUT RS10525
gene id: 563040:SAUT_RS10525
uniprot id: E0URV6
names: Similarity
messages: Belongs to the hemerythrin family.

563040:SAUT RS10355
gene id: 563040:SAUT_RS10355
uniprot id: E0URS2
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS07710
gene id: 563040:SAUT_RS07710
uniprot id: E0UUR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

563040:SAUT RS07545
gene id: 563040:SAUT_RS07545
uniprot id: E0UUN5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

563040:SAUT RS04640
gene id: 563040:SAUT_RS04640
uniprot id: E0URL4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

563040:SAUT RS07575
gene id: 563040:SAUT_RS07575
uniprot id: E0UUP1
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

563040:SAUT RS09750
gene id: 563040:SAUT_RS09750
uniprot id: E0UR12
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS02370
gene id: 563040:SAUT_RS02370
uniprot id: E0UP58
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

563040:SAUT RS07385
gene id: 563040:SAUT_RS07385
uniprot id: E0UUD3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

563040:SAUT RS10535
gene id: 563040:SAUT_RS10535
uniprot id: E0URV8
names: Similarity
messages: Belongs to the DEAD box helicase family.

563040:SAUT RS10370
gene id: 563040:SAUT_RS10370
uniprot id: E0URS5
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS06725
gene id: 563040:SAUT_RS06725
uniprot id: E0UTT2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

563040:SAUT RS09525
gene id: 563040:SAUT_RS09525
uniprot id: E0UQQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

563040:SAUT RS01480
gene id: 563040:SAUT_RS01480
uniprot id: E0UU37
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS05370
gene id: 563040:SAUT_RS05370
uniprot id: E0USD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

563040:SAUT RS05305
gene id: 563040:SAUT_RS05305
uniprot id: E0USC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

563040:SAUT RS03390
gene id: 563040:SAUT_RS03390
uniprot id: E0UQ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

563040:SAUT RS06435
gene id: 563040:SAUT_RS06435
uniprot id: E0UTF3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

563040:SAUT RS05125
gene id: 563040:SAUT_RS05125
uniprot id: E0US32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

563040:SAUT RS04235
gene id: 563040:SAUT_RS04235
uniprot id: E0UR67
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

563040:SAUT RS01815
gene id: 563040:SAUT_RS01815
uniprot id: E0UUH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

563040:SAUT RS07265
gene id: 563040:SAUT_RS07265
uniprot id: E0UUA9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

563040:SAUT RS09075
gene id: 563040:SAUT_RS09075
uniprot id: E0UQ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

563040:SAUT RS03040
gene id: 563040:SAUT_RS03040
uniprot id: E0UPR0
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

563040:SAUT RS03135
gene id: 563040:SAUT_RS03135
uniprot id: E0UPZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

563040:SAUT RS00715
gene id: 563040:SAUT_RS00715
uniprot id: E0UT89
names: Similarity
messages: Belongs to the polysaccharide synthase family.

563040:SAUT RS00430
gene id: 563040:SAUT_RS00430
uniprot id: E0USV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

563040:SAUT RS01675
gene id: 563040:SAUT_RS01675
uniprot id: E0UUE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

563040:SAUT RS02120
gene id: 563040:SAUT_RS02120
uniprot id: E0UUV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

563040:SAUT RS01190
gene id: 563040:SAUT_RS01190
uniprot id: E0UTQ7
names: Similarity
messages: Belongs to the CvfB family.

563040:SAUT RS07080
gene id: 563040:SAUT_RS07080
uniprot id: E0UU73
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

563040:SAUT RS06795
gene id: 563040:SAUT_RS06795
uniprot id: E0UTU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

563040:SAUT RS04410
gene id: 563040:SAUT_RS04410
uniprot id: E0URA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

563040:SAUT RS04415
gene id: 563040:SAUT_RS04415
uniprot id: E0URA2
names: Similarity
messages: Belongs to the GSP E family.

563040:SAUT RS04575
gene id: 563040:SAUT_RS04575
uniprot id: E0URK0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS05350
gene id: 563040:SAUT_RS05350
uniprot id: E0USD5
names: Similarity
messages: Belongs to the glutamate synthase family.

563040:SAUT RS02855
gene id: 563040:SAUT_RS02855
uniprot id: E0UPM4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

563040:SAUT RS00970
gene id: 563040:SAUT_RS00970
uniprot id: E0UTL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

563040:SAUT RS00595
gene id: 563040:SAUT_RS00595
uniprot id: E0UT65
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

563040:SAUT RS00400
gene id: 563040:SAUT_RS00400
uniprot id: E0USU9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

563040:SAUT RS05610
gene id: 563040:SAUT_RS05610
uniprot id: E0USI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

563040:SAUT RS03565
gene id: 563040:SAUT_RS03565
uniprot id: E0UQE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

563040:SAUT RS08665
gene id: 563040:SAUT_RS08665
uniprot id: E0UPU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

563040:SAUT RS05110
gene id: 563040:SAUT_RS05110
uniprot id: E0US29
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

563040:SAUT RS08460
gene id: 563040:SAUT_RS08460
uniprot id: E0UPI6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

563040:SAUT RS06240
gene id: 563040:SAUT_RS06240
uniprot id: E0UT35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

563040:SAUT RS00745
gene id: 563040:SAUT_RS00745
uniprot id: E0UT95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

563040:SAUT RS00120
gene id: 563040:SAUT_RS00120
uniprot id: E0UP40
names: Similarity
messages: Belongs to the GSP E family.

563040:SAUT RS03530
gene id: 563040:SAUT_RS03530
uniprot id: E0UQE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

563040:SAUT RS07300
gene id: 563040:SAUT_RS07300
uniprot id: E0UUB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

563040:SAUT RS03930
gene id: 563040:SAUT_RS03930
uniprot id: E0UQU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

563040:SAUT RS05360
gene id: 563040:SAUT_RS05360
uniprot id: E0USD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

563040:SAUT RS08585
gene id: 563040:SAUT_RS08585
uniprot id: E0UPT1
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

563040:SAUT RS10765
gene id: 563040:SAUT_RS10765
uniprot id: E0US77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

563040:SAUT RS02495
gene id: 563040:SAUT_RS02495
uniprot id: E0UP83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

563040:SAUT RS10855
gene id: 563040:SAUT_RS10855
uniprot id: E0US91
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS09950
gene id: 563040:SAUT_RS09950
uniprot id: E0UR52
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

563040:SAUT RS04490
gene id: 563040:SAUT_RS04490
uniprot id: E0URB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

563040:SAUT RS04030
gene id: 563040:SAUT_RS04030
uniprot id: E0UQW0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

563040:SAUT RS07075
gene id: 563040:SAUT_RS07075
uniprot id: E0UU72
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

563040:SAUT RS07115
gene id: 563040:SAUT_RS07115
uniprot id: E0UU80
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS00475
gene id: 563040:SAUT_RS00475
uniprot id: E0USW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

563040:SAUT RS05880
gene id: 563040:SAUT_RS05880
uniprot id: E0USN9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

563040:SAUT RS05820
gene id: 563040:SAUT_RS05820
uniprot id: E0USM6
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS06510
gene id: 563040:SAUT_RS06510
uniprot id: E0UTG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

563040:SAUT RS07835
gene id: 563040:SAUT_RS07835
uniprot id: E0UV15
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

563040:SAUT RS01170
gene id: 563040:SAUT_RS01170
uniprot id: E0UTQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

563040:SAUT RS06325
gene id: 563040:SAUT_RS06325
uniprot id: E0UT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapB family.
messages: Periplasm

563040:SAUT RS01600
gene id: 563040:SAUT_RS01600
uniprot id: E0UU56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

563040:SAUT RS03240
gene id: 563040:SAUT_RS03240
uniprot id: E0UQ17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

563040:SAUT RS10065
gene id: 563040:SAUT_RS10065
uniprot id: E0URE5
names: Subcellular Location Annotation
messages: Periplasm

563040:SAUT RS07925
gene id: 563040:SAUT_RS07925
uniprot id: E0UV33
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

563040:SAUT RS01350
gene id: 563040:SAUT_RS01350
uniprot id: E0UU12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

563040:SAUT RS04960
gene id: 563040:SAUT_RS04960
uniprot id: E0URZ9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

563040:SAUT RS07200
gene id: 563040:SAUT_RS07200
uniprot id: E0UU96
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

563040:SAUT RS08925
gene id: 563040:SAUT_RS08925
uniprot id: E0UQ59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

563040:SAUT RS02985
gene id: 563040:SAUT_RS02985
uniprot id: E0UPP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

563040:SAUT RS09250
gene id: 563040:SAUT_RS09250
uniprot id: E0UQC4
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS07240
gene id: 563040:SAUT_RS07240
uniprot id: E0UUA4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

563040:SAUT RS00535
gene id: 563040:SAUT_RS00535
uniprot id: E0USX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

563040:SAUT RS08765
gene id: 563040:SAUT_RS08765
uniprot id: E0UPW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

563040:SAUT RS01690
gene id: 563040:SAUT_RS01690
uniprot id: E0UUE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

563040:SAUT RS03885
gene id: 563040:SAUT_RS03885
uniprot id: E0UQT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

563040:SAUT RS02795
gene id: 563040:SAUT_RS02795
uniprot id: E0UPL4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

563040:SAUT RS04685
gene id: 563040:SAUT_RS04685
uniprot id: E0URM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

563040:SAUT RS10650
gene id: 563040:SAUT_RS10650
uniprot id: E0URY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

563040:SAUT RS01445
gene id: 563040:SAUT_RS01445
uniprot id: E0UU30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

563040:SAUT RS04385
gene id: 563040:SAUT_RS04385
uniprot id: E0UR96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

563040:SAUT RS03085
gene id: 563040:SAUT_RS03085
uniprot id: E0UPR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

563040:SAUT RS02850
gene id: 563040:SAUT_RS02850
uniprot id: E0UPM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

563040:SAUT RS09265
gene id: 563040:SAUT_RS09265
uniprot id: E0UQJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

563040:SAUT RS10340
gene id: 563040:SAUT_RS10340
uniprot id: E0URR9
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS10820
gene id: 563040:SAUT_RS10820
uniprot id: E0US84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

563040:SAUT RS05510
gene id: 563040:SAUT_RS05510
uniprot id: E0USG7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS04590
gene id: 563040:SAUT_RS04590
uniprot id: E0URK3
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS07535
gene id: 563040:SAUT_RS07535
uniprot id: E0UUN3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

563040:SAUT RS03710
gene id: 563040:SAUT_RS03710
uniprot id: E0UQH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

563040:SAUT RS08785
gene id: 563040:SAUT_RS08785
uniprot id: E0UPX0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

563040:SAUT RS08445
gene id: 563040:SAUT_RS08445
uniprot id: E0UPI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

563040:SAUT RS10280
gene id: 563040:SAUT_RS10280
uniprot id: E0URI5
names: Similarity
messages: Belongs to the ArsC family.

563040:SAUT RS05595
gene id: 563040:SAUT_RS05595
uniprot id: E0USI3
names: Similarity
messages: Belongs to the glutamate synthase family.

563040:SAUT RS02185
gene id: 563040:SAUT_RS02185
uniprot id: E0UUX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

563040:SAUT RS09230
gene id: 563040:SAUT_RS09230
uniprot id: E0UQC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

563040:SAUT RS08040
gene id: 563040:SAUT_RS08040
uniprot id: E0UV52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

563040:SAUT RS09990
gene id: 563040:SAUT_RS09990
uniprot id: E0URD0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

563040:SAUT RS05070
gene id: 563040:SAUT_RS05070
uniprot id: E0US21
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

563040:SAUT RS05565
gene id: 563040:SAUT_RS05565
uniprot id: E0USH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

563040:SAUT RS01925
gene id: 563040:SAUT_RS01925
uniprot id: E0UUJ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

563040:SAUT RS00125
gene id: 563040:SAUT_RS00125
uniprot id: E0UP41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

563040:SAUT RS02595
gene id: 563040:SAUT_RS02595
uniprot id: E0UPA3
names: Similarity
messages: Belongs to the DEAD box helicase family.

563040:SAUT RS05755
gene id: 563040:SAUT_RS05755
uniprot id: E0USL3
names: Similarity
messages: Belongs to the YggT family.

563040:SAUT RS01670
gene id: 563040:SAUT_RS01670
uniprot id: E0UUE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

563040:SAUT RS00585
gene id: 563040:SAUT_RS00585
uniprot id: E0UT63
names: Similarity
messages: Belongs to the asparagine synthetase family.

563040:SAUT RS10585
gene id: 563040:SAUT_RS10585
uniprot id: E0URW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

563040:SAUT RS02860
gene id: 563040:SAUT_RS02860
uniprot id: E0UPM5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

563040:SAUT RS06610
gene id: 563040:SAUT_RS06610
uniprot id: E0UTI8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

563040:SAUT RS01085
gene id: 563040:SAUT_RS01085
uniprot id: E0UTN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

563040:SAUT RS09410
gene id: 563040:SAUT_RS09410
uniprot id: E0UQM8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS01630
gene id: 563040:SAUT_RS01630
uniprot id: E0UU62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

563040:SAUT RS03650
gene id: 563040:SAUT_RS03650
uniprot id: E0UQG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS03685
gene id: 563040:SAUT_RS03685
uniprot id: E0UQG9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

563040:SAUT RS06270
gene id: 563040:SAUT_RS06270
uniprot id: E0UT41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

563040:SAUT RS00665
gene id: 563040:SAUT_RS00665
uniprot id: E0UT79
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

563040:SAUT RS10705
gene id: 563040:SAUT_RS10705
uniprot id: E0US65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

563040:SAUT RS03250
gene id: 563040:SAUT_RS03250
uniprot id: E0UQ19
names: Subcellular Location Annotation
messages: Cytoplasm

563040:SAUT RS08640
gene id: 563040:SAUT_RS08640
uniprot id: E0UPU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

563040:SAUT RS02770
gene id: 563040:SAUT_RS02770
uniprot id: E0UPL0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS02760
gene id: 563040:SAUT_RS02760
uniprot id: E0UPK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

563040:SAUT RS06625
gene id: 563040:SAUT_RS06625
uniprot id: E0UTJ1
names: Similarity
messages: Belongs to the peptidase A31 family.

563040:SAUT RS05805
gene id: 563040:SAUT_RS05805
uniprot id: E0USM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

563040:SAUT RS02830
gene id: 563040:SAUT_RS02830
uniprot id: E0UPL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

563040:SAUT RS00500
gene id: 563040:SAUT_RS00500
uniprot id: E0USX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

563040:SAUT RS00035
gene id: 563040:SAUT_RS00035
uniprot id: E0UP23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

563040:SAUT RS09430
gene id: 563040:SAUT_RS09430
uniprot id: E0UQN2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

563040:SAUT RS08130
gene id: 563040:SAUT_RS08130
uniprot id: E0UV70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

563040:SAUT RS11240
gene id: 563040:SAUT_RS11240
uniprot id: E0UQ38
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS01385
gene id: 563040:SAUT_RS01385
uniprot id: E0UU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

563040:SAUT RS02440
gene id: 563040:SAUT_RS02440
uniprot id: E0UP72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

563040:SAUT RS03425
gene id: 563040:SAUT_RS03425
uniprot id: E0UQ50
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS04625
gene id: 563040:SAUT_RS04625
uniprot id: E0URL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

563040:SAUT RS09955
gene id: 563040:SAUT_RS09955
uniprot id: E0UR53
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

563040:SAUT RS09040
gene id: 563040:SAUT_RS09040
uniprot id: E0UQ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

563040:SAUT RS01090
gene id: 563040:SAUT_RS01090
uniprot id: E0UTN7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

563040:SAUT RS10345
gene id: 563040:SAUT_RS10345
uniprot id: E0URS0
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS07485
gene id: 563040:SAUT_RS07485
uniprot id: E0UUM3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS06415
gene id: 563040:SAUT_RS06415
uniprot id: E0UTE9
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

563040:SAUT RS06175
gene id: 563040:SAUT_RS06175
uniprot id: E0UT22
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

563040:SAUT RS01305
gene id: 563040:SAUT_RS01305
uniprot id: E0UU03
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

563040:SAUT RS08090
gene id: 563040:SAUT_RS08090
uniprot id: E0UV62
names: Subcellular Location Annotation
messages: Cytoplasm

563040:SAUT RS09735
gene id: 563040:SAUT_RS09735
uniprot id: E0UR09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS08635
gene id: 563040:SAUT_RS08635
uniprot id: E0UPU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

563040:SAUT RS03935
gene id: 563040:SAUT_RS03935
uniprot id: E0UQU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

563040:SAUT RS04670
gene id: 563040:SAUT_RS04670
uniprot id: E0URM0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

563040:SAUT RS07520
gene id: 563040:SAUT_RS07520
uniprot id: E0UUN0
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS00055
gene id: 563040:SAUT_RS00055
uniprot id: E0UP27
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

563040:SAUT RS06715
gene id: 563040:SAUT_RS06715
uniprot id: E0UTT0
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS03840
gene id: 563040:SAUT_RS03840
uniprot id: E0UQS2
names: Similarity
messages: Belongs to the RutC family.

563040:SAUT RS04390
gene id: 563040:SAUT_RS04390
uniprot id: E0UR97
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

563040:SAUT RS09255
gene id: 563040:SAUT_RS09255
uniprot id: E0UQC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

563040:SAUT RS00875
gene id: 563040:SAUT_RS00875
uniprot id: E0UTC5
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS03925
gene id: 563040:SAUT_RS03925
uniprot id: E0UQT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

563040:SAUT RS04580
gene id: 563040:SAUT_RS04580
uniprot id: E0URK1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

563040:SAUT RS03755
gene id: 563040:SAUT_RS03755
uniprot id: E0UQI4
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

563040:SAUT RS08400
gene id: 563040:SAUT_RS08400
uniprot id: E0UPH5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

563040:SAUT RS06405
gene id: 563040:SAUT_RS06405
uniprot id: E0UTE7
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

563040:SAUT RS04710
gene id: 563040:SAUT_RS04710
uniprot id: E0URM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

563040:SAUT RS04835
gene id: 563040:SAUT_RS04835
uniprot id: E0URQ3
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS01330
gene id: 563040:SAUT_RS01330
uniprot id: E0UU08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

563040:SAUT RS02590
gene id: 563040:SAUT_RS02590
uniprot id: E0UPA2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS02690
gene id: 563040:SAUT_RS02690
uniprot id: E0UPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

563040:SAUT RS09935
gene id: 563040:SAUT_RS09935
uniprot id: E0UR49
names: Cofactor
names: Similarity
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.

563040:SAUT RS09060
gene id: 563040:SAUT_RS09060
uniprot id: E0UQ85
names: Similarity
messages: Belongs to the GARS family.

563040:SAUT RS02015
gene id: 563040:SAUT_RS02015
uniprot id: E0UUT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

563040:SAUT RS01390
gene id: 563040:SAUT_RS01390
uniprot id: E0UU20
names: Similarity
messages: Belongs to the ABC transporter superfamily.

563040:SAUT RS04480
gene id: 563040:SAUT_RS04480
uniprot id: E0URB5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

563040:SAUT RS06650
gene id: 563040:SAUT_RS06650
uniprot id: E0UTJ6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

563040:SAUT RS08430
gene id: 563040:SAUT_RS08430
uniprot id: E0UPI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

563040:SAUT RS01095
gene id: 563040:SAUT_RS01095
uniprot id: E0UTN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

563040:SAUT RS06260
gene id: 563040:SAUT_RS06260
uniprot id: E0UT39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

563040:SAUT RS08475
gene id: 563040:SAUT_RS08475
uniprot id: E0UPI8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

563040:SAUT RS02040
gene id: 563040:SAUT_RS02040
uniprot id: E0UUU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

563040:SAUT RS07805
gene id: 563040:SAUT_RS07805
uniprot id: E0UV09
names: Similarity
messages: Belongs to the peptidase M1 family.

563040:SAUT RS01900
gene id: 563040:SAUT_RS01900
uniprot id: E0UUJ0
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

563040:SAUT RS10240
gene id: 563040:SAUT_RS10240
uniprot id: E0URH7
names: Similarity
messages: Belongs to the UPF0235 family.

563040:SAUT RS06570
gene id: 563040:SAUT_RS06570
uniprot id: E0UTI0
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

563040:SAUT RS01730
gene id: 563040:SAUT_RS01730
uniprot id: E0UUF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

563040:SAUT RS06845
gene id: 563040:SAUT_RS06845
uniprot id: E0UTV6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

563040:SAUT RS06960
gene id: 563040:SAUT_RS06960
uniprot id: E0UTX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

563040:SAUT RS03860
gene id: 563040:SAUT_RS03860
uniprot id: E0UQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

563040:SAUT RS04135
gene id: 563040:SAUT_RS04135
uniprot id: E0UQX5
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS02905
gene id: 563040:SAUT_RS02905
uniprot id: E0UPN4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

563040:SAUT RS02385
gene id: 563040:SAUT_RS02385
uniprot id: E0UP61
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

563040:SAUT RS09010
gene id: 563040:SAUT_RS09010
uniprot id: E0UQ76
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

563040:SAUT RS05415
gene id: 563040:SAUT_RS05415
uniprot id: E0USE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

563040:SAUT RS06745
gene id: 563040:SAUT_RS06745
uniprot id: E0UTT6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

563040:SAUT RS09175
gene id: 563040:SAUT_RS09175
uniprot id: E0UQA9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

563040:SAUT RS03585
gene id: 563040:SAUT_RS03585
uniprot id: E0UQF2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

563040:SAUT RS08260
gene id: 563040:SAUT_RS08260
uniprot id: E0UPE8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

563040:SAUT RS07655
gene id: 563040:SAUT_RS07655
uniprot id: E0UUQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

563040:SAUT RS10295
gene id: 563040:SAUT_RS10295
uniprot id: E0URI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

563040:SAUT RS06620
gene id: 563040:SAUT_RS06620
uniprot id: E0UTJ0
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

563040:SAUT RS05690
gene id: 563040:SAUT_RS05690
uniprot id: E0USK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

563040:SAUT RS08220
gene id: 563040:SAUT_RS08220
uniprot id: E0UPE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

563040:SAUT RS08370
gene id: 563040:SAUT_RS08370
uniprot id: E0UPH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

563040:SAUT RS09865
gene id: 563040:SAUT_RS09865
uniprot id: E0UR35
names: Similarity
messages: Belongs to the ModE family.

563040:SAUT RS06450
gene id: 563040:SAUT_RS06450
uniprot id: E0UTF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Cell inner membrane
messages: Membrane

563040:SAUT RS00435
gene id: 563040:SAUT_RS00435
uniprot id: E0USV8
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

563040:SAUT RS03395
gene id: 563040:SAUT_RS03395
uniprot id: E0UQ44
names: Similarity
messages: Belongs to the P(II) protein family.

563040:SAUT RS07220
gene id: 563040:SAUT_RS07220
uniprot id: E0UUA0
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS01310
gene id: 563040:SAUT_RS01310
uniprot id: E0UU04
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

563040:SAUT RS02945
gene id: 563040:SAUT_RS02945
uniprot id: E0UPP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

563040:SAUT RS05120
gene id: 563040:SAUT_RS05120
uniprot id: E0US31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

563040:SAUT RS01720
gene id: 563040:SAUT_RS01720
uniprot id: E0UUF3
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS10575
gene id: 563040:SAUT_RS10575
uniprot id: E0URW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

563040:SAUT RS02435
gene id: 563040:SAUT_RS02435
uniprot id: E0UP71
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

563040:SAUT RS08340
gene id: 563040:SAUT_RS08340
uniprot id: E0UPG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

563040:SAUT RS01065
gene id: 563040:SAUT_RS01065
uniprot id: E0UTN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

563040:SAUT RS06095
gene id: 563040:SAUT_RS06095
uniprot id: E0UT04
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

563040:SAUT RS01715
gene id: 563040:SAUT_RS01715
uniprot id: E0UUF2
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS01290
gene id: 563040:SAUT_RS01290
uniprot id: E0UU00
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

563040:SAUT RS10885
gene id: 563040:SAUT_RS10885
uniprot id: E0US97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

563040:SAUT RS04830
gene id: 563040:SAUT_RS04830
uniprot id: E0URQ2
names: Similarity
messages: Belongs to the UPF0111 family.

563040:SAUT RS08910
gene id: 563040:SAUT_RS08910
uniprot id: E0UQ56
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

563040:SAUT RS05170
gene id: 563040:SAUT_RS05170
uniprot id: E0US42
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS02575
gene id: 563040:SAUT_RS02575
uniprot id: E0UP99
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

563040:SAUT RS04000
gene id: 563040:SAUT_RS04000
uniprot id: E0UQV4
names: Similarity
messages: Belongs to the fabD family.

563040:SAUT RS01050
gene id: 563040:SAUT_RS01050
uniprot id: E0UTM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

563040:SAUT RS07955
gene id: 563040:SAUT_RS07955
uniprot id: E0UV39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

563040:SAUT RS07705
gene id: 563040:SAUT_RS07705
uniprot id: E0UUR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

563040:SAUT RS02705
gene id: 563040:SAUT_RS02705
uniprot id: E0UPC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

563040:SAUT RS00525
gene id: 563040:SAUT_RS00525
uniprot id: E0USX7
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS03410
gene id: 563040:SAUT_RS03410
uniprot id: E0UQ47
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

563040:SAUT RS08955
gene id: 563040:SAUT_RS08955
uniprot id: E0UQ65
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

563040:SAUT RS08485
gene id: 563040:SAUT_RS08485
uniprot id: E0UPJ0
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

563040:SAUT RS03515
gene id: 563040:SAUT_RS03515
uniprot id: E0UQD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

563040:SAUT RS07540
gene id: 563040:SAUT_RS07540
uniprot id: E0UUN4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

563040:SAUT RS06770
gene id: 563040:SAUT_RS06770
uniprot id: E0UTU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

563040:SAUT RS10740
gene id: 563040:SAUT_RS10740
uniprot id: E0US72
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

563040:SAUT RS07460
gene id: 563040:SAUT_RS07460
uniprot id: E0UUL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

563040:SAUT RS03525
gene id: 563040:SAUT_RS03525
uniprot id: E0UQE1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

563040:SAUT RS04825
gene id: 563040:SAUT_RS04825
uniprot id: E0URQ1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

563040:SAUT RS04315
gene id: 563040:SAUT_RS04315
uniprot id: E0UR84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

563040:SAUT RS06445
gene id: 563040:SAUT_RS06445
uniprot id: E0UTF5
names: Similarity
messages: Belongs to the MotB family.

563040:SAUT RS05185
gene id: 563040:SAUT_RS05185
uniprot id: E0US45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

563040:SAUT RS11005
gene id: 563040:SAUT_RS11005
uniprot id: E0UUJ9
names: Subcellular Location Annotation
messages: Cell inner membrane

563040:SAUT RS08825
gene id: 563040:SAUT_RS08825
uniprot id: E0UPX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

563040:SAUT RS00650
gene id: 563040:SAUT_RS00650
uniprot id: E0UT76
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

563040:SAUT RS04520
gene id: 563040:SAUT_RS04520
uniprot id: E0URC3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

563040:SAUT RS01590
gene id: 563040:SAUT_RS01590
uniprot id: E0UU54
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

563040:SAUT RS01135
gene id: 563040:SAUT_RS01135
uniprot id: E0UTP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

563040:SAUT RS07670
gene id: 563040:SAUT_RS07670
uniprot id: E0UUQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

563040:SAUT RS00270
gene id: 563040:SAUT_RS00270
uniprot id: E0USS5
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS02630
gene id: 563040:SAUT_RS02630
uniprot id: E0UPB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

563040:SAUT RS01070
gene id: 563040:SAUT_RS01070
uniprot id: E0UTN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

563040:SAUT RS03570
gene id: 563040:SAUT_RS03570
uniprot id: E0UQE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

563040:SAUT RS10275
gene id: 563040:SAUT_RS10275
uniprot id: E0URI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

563040:SAUT RS02365
gene id: 563040:SAUT_RS02365
uniprot id: E0UP57
names: Similarity
messages: Belongs to the phosphohexose mutase family.

563040:SAUT RS09055
gene id: 563040:SAUT_RS09055
uniprot id: E0UQ84
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS01175
gene id: 563040:SAUT_RS01175
uniprot id: E0UTQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

563040:SAUT RS06355
gene id: 563040:SAUT_RS06355
uniprot id: E0UTD7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

563040:SAUT RS09860
gene id: 563040:SAUT_RS09860
uniprot id: E0UR34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

563040:SAUT RS05670
gene id: 563040:SAUT_RS05670
uniprot id: E0USJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

563040:SAUT RS10895
gene id: 563040:SAUT_RS10895
uniprot id: E0US99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

563040:SAUT RS10210
gene id: 563040:SAUT_RS10210
uniprot id: E0URH1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

563040:SAUT RS09760
gene id: 563040:SAUT_RS09760
uniprot id: E0UR14
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS08620
gene id: 563040:SAUT_RS08620
uniprot id: E0UPT8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

563040:SAUT RS09855
gene id: 563040:SAUT_RS09855
uniprot id: E0UR33
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

563040:SAUT RS01620
gene id: 563040:SAUT_RS01620
uniprot id: E0UU60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

563040:SAUT RS04045
gene id: 563040:SAUT_RS04045
uniprot id: E0UQW3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

563040:SAUT RS06995
gene id: 563040:SAUT_RS06995
uniprot id: E0UTY7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

563040:SAUT RS00520
gene id: 563040:SAUT_RS00520
uniprot id: E0USX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

563040:SAUT RS04270
gene id: 563040:SAUT_RS04270
uniprot id: E0UR74
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

563040:SAUT RS06060
gene id: 563040:SAUT_RS06060
uniprot id: E0USZ7
names: Similarity
messages: Belongs to the MEMO1 family.

563040:SAUT RS10685
gene id: 563040:SAUT_RS10685
uniprot id: E0US60
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

563040:SAUT RS09465
gene id: 563040:SAUT_RS09465
uniprot id: E0UQN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

563040:SAUT RS05585
gene id: 563040:SAUT_RS05585
uniprot id: E0USI1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

563040:SAUT RS01300
gene id: 563040:SAUT_RS01300
uniprot id: E0UU02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

563040:SAUT RS06950
gene id: 563040:SAUT_RS06950
uniprot id: E0UTX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

563040:SAUT RS01490
gene id: 563040:SAUT_RS01490
uniprot id: E0UU39
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

563040:SAUT RS00750
gene id: 563040:SAUT_RS00750
uniprot id: E0UT96
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

563040:SAUT RS01510
gene id: 563040:SAUT_RS01510
uniprot id: E0UU43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

563040:SAUT RS08805
gene id: 563040:SAUT_RS08805
uniprot id: E0UPX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

563040:SAUT RS06905
gene id: 563040:SAUT_RS06905
uniprot id: E0UTW8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

563040:SAUT RS01055
gene id: 563040:SAUT_RS01055
uniprot id: E0UTN0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

563040:SAUT RS00215
gene id: 563040:SAUT_RS00215
uniprot id: E0USR4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

563040:SAUT RS03950
gene id: 563040:SAUT_RS03950
uniprot id: E0UQU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

563040:SAUT RS08780
gene id: 563040:SAUT_RS08780
uniprot id: E0UPW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

563040:SAUT RS00040
gene id: 563040:SAUT_RS00040
uniprot id: E0UP24
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

563040:SAUT RS01970
gene id: 563040:SAUT_RS01970
uniprot id: E0UUK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS10565
gene id: 563040:SAUT_RS10565
uniprot id: E0URW4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

563040:SAUT RS05905
gene id: 563040:SAUT_RS05905
uniprot id: E0USP4
names: Similarity
messages: Belongs to the nitroreductase family.

563040:SAUT RS04380
gene id: 563040:SAUT_RS04380
uniprot id: E0UR95
names: Similarity
messages: Belongs to the XseB family.

563040:SAUT RS09520
gene id: 563040:SAUT_RS09520
uniprot id: E0UQQ0
names: Similarity
messages: Belongs to the glutamine synthetase family.

563040:SAUT RS02940
gene id: 563040:SAUT_RS02940
uniprot id: E0UPP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

563040:SAUT RS10285
gene id: 563040:SAUT_RS10285
uniprot id: E0URI6
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

563040:SAUT RS09245
gene id: 563040:SAUT_RS09245
uniprot id: E0UQC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

563040:SAUT RS01595
gene id: 563040:SAUT_RS01595
uniprot id: E0UU55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

563040:SAUT RS01505
gene id: 563040:SAUT_RS01505
uniprot id: E0UU42
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

563040:SAUT RS08675
gene id: 563040:SAUT_RS08675
uniprot id: E0UPU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

563040:SAUT RS02405
gene id: 563040:SAUT_RS02405
uniprot id: E0UP65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

563040:SAUT RS06185
gene id: 563040:SAUT_RS06185
uniprot id: E0UT24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

563040:SAUT RS09730
gene id: 563040:SAUT_RS09730
uniprot id: E0UR08
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

563040:SAUT RS02360
gene id: 563040:SAUT_RS02360
uniprot id: E0UP56
names: Similarity
messages: Belongs to the phosphohexose mutase family.

563040:SAUT RS00830
gene id: 563040:SAUT_RS00830
uniprot id: E0UTB4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

563040:SAUT RS09015
gene id: 563040:SAUT_RS09015
uniprot id: E0UQ77
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

563040:SAUT RS07480
gene id: 563040:SAUT_RS07480
uniprot id: E0UUM2
names: Similarity
messages: Belongs to the MipA/OmpV family.

563040:SAUT RS08970
gene id: 563040:SAUT_RS08970
uniprot id: E0UQ68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

563040:SAUT RS09885
gene id: 563040:SAUT_RS09885
uniprot id: E0UR39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

563040:SAUT RS10720
gene id: 563040:SAUT_RS10720
uniprot id: E0US68
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

563040:SAUT RS03760
gene id: 563040:SAUT_RS03760
uniprot id: E0UQI5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

563040:SAUT RS09375
gene id: 563040:SAUT_RS09375
uniprot id: E0UQM1
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS09560
gene id: 563040:SAUT_RS09560
uniprot id: E0UQQ8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

563040:SAUT RS04020
gene id: 563040:SAUT_RS04020
uniprot id: E0UQV8
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS04800
gene id: 563040:SAUT_RS04800
uniprot id: E0URP6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

563040:SAUT RS02380
gene id: 563040:SAUT_RS02380
uniprot id: E0UP60
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

563040:SAUT RS09665
gene id: 563040:SAUT_RS09665
uniprot id: E0UQZ5
names: Similarity
messages: Belongs to the UPF0102 family.

563040:SAUT RS06720
gene id: 563040:SAUT_RS06720
uniprot id: E0UTT1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

563040:SAUT RS08100
gene id: 563040:SAUT_RS08100
uniprot id: E0UV64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

563040:SAUT RS06010
gene id: 563040:SAUT_RS06010
uniprot id: E0USY7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

563040:SAUT RS00180
gene id: 563040:SAUT_RS00180
uniprot id: E0UP52
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

563040:SAUT RS08160
gene id: 563040:SAUT_RS08160
uniprot id: E0UPC8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

563040:SAUT RS08010
gene id: 563040:SAUT_RS08010
uniprot id: E0UV46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

563040:SAUT RS07410
gene id: 563040:SAUT_RS07410
uniprot id: E0UUD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

563040:SAUT RS06600
gene id: 563040:SAUT_RS06600
uniprot id: E0UTI6
names: Similarity
messages: Belongs to the HypD family.

563040:SAUT RS08990
gene id: 563040:SAUT_RS08990
uniprot id: E0UQ72
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

563040:SAUT RS04125
gene id: 563040:SAUT_RS04125
uniprot id: E0UQX3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

563040:SAUT RS08550
gene id: 563040:SAUT_RS08550
uniprot id: E0UPS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

563040:SAUT RS01905
gene id: 563040:SAUT_RS01905
uniprot id: E0UUJ1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

563040:SAUT RS02160
gene id: 563040:SAUT_RS02160
uniprot id: E0UUW7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

563040:SAUT RS04330
gene id: 563040:SAUT_RS04330
uniprot id: E0UR87
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

563040:SAUT RS01285
gene id: 563040:SAUT_RS01285
uniprot id: E0UTZ9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

563040:SAUT RS06910
gene id: 563040:SAUT_RS06910
uniprot id: E0UTW9
names: Similarity
messages: Belongs to the ArsC family.

563040:SAUT RS03180
gene id: 563040:SAUT_RS03180
uniprot id: E0UQ05
names: Similarity
messages: Belongs to the peptidase M24B family.

563040:SAUT RS07695
gene id: 563040:SAUT_RS07695
uniprot id: E0UUR4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

563040:SAUT RS08020
gene id: 563040:SAUT_RS08020
uniprot id: E0UV48
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

563040:SAUT RS01280
gene id: 563040:SAUT_RS01280
uniprot id: E0UTZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

563040:SAUT RS02165
gene id: 563040:SAUT_RS02165
uniprot id: E0UUW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

563040:SAUT RS06245
gene id: 563040:SAUT_RS06245
uniprot id: E0UT36
names: Similarity
messages: Belongs to the LacAB/RpiB family.

563040:SAUT RS01115
gene id: 563040:SAUT_RS01115
uniprot id: E0UTP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

563040:SAUT RS02650
gene id: 563040:SAUT_RS02650
uniprot id: E0UPB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

563040:SAUT RS08105
gene id: 563040:SAUT_RS08105
uniprot id: E0UV65
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

563040:SAUT RS00955
gene id: 563040:SAUT_RS00955
uniprot id: E0UTL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

563040:SAUT RS01455
gene id: 563040:SAUT_RS01455
uniprot id: E0UU32
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

563040:SAUT RS01130
gene id: 563040:SAUT_RS01130
uniprot id: E0UTP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

563040:SAUT RS06645
gene id: 563040:SAUT_RS06645
uniprot id: E0UTJ5
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS02100
gene id: 563040:SAUT_RS02100
uniprot id: E0UUV4
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

563040:SAUT RS02955
gene id: 563040:SAUT_RS02955
uniprot id: E0UPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

563040:SAUT RS08725
gene id: 563040:SAUT_RS08725
uniprot id: E0UPV9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

563040:SAUT RS04925
gene id: 563040:SAUT_RS04925
uniprot id: E0URZ2
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

563040:SAUT RS00735
gene id: 563040:SAUT_RS00735
uniprot id: E0UT93
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

563040:SAUT RS08230
gene id: 563040:SAUT_RS08230
uniprot id: E0UPE2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS04680
gene id: 563040:SAUT_RS04680
uniprot id: E0URM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

563040:SAUT RS06365
gene id: 563040:SAUT_RS06365
uniprot id: E0UTD9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

563040:SAUT RS09975
gene id: 563040:SAUT_RS09975
uniprot id: E0URC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

563040:SAUT RS09675
gene id: 563040:SAUT_RS09675
uniprot id: E0UQZ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

563040:SAUT RS06145
gene id: 563040:SAUT_RS06145
uniprot id: E0UT16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS01615
gene id: 563040:SAUT_RS01615
uniprot id: E0UU59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

563040:SAUT RS01145
gene id: 563040:SAUT_RS01145
uniprot id: E0UTP8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

563040:SAUT RS05855
gene id: 563040:SAUT_RS05855
uniprot id: E0USN3
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

563040:SAUT RS10735
gene id: 563040:SAUT_RS10735
uniprot id: E0US71
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

563040:SAUT RS07250
gene id: 563040:SAUT_RS07250
uniprot id: E0UUA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

563040:SAUT RS02550
gene id: 563040:SAUT_RS02550
uniprot id: E0UP94
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS00975
gene id: 563040:SAUT_RS00975
uniprot id: E0UTL4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS06765
gene id: 563040:SAUT_RS06765
uniprot id: E0UTU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

563040:SAUT RS07450
gene id: 563040:SAUT_RS07450
uniprot id: E0UUL6
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

563040:SAUT RS02330
gene id: 563040:SAUT_RS02330
uniprot id: E0UV02
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

563040:SAUT RS03640
gene id: 563040:SAUT_RS03640
uniprot id: E0UQG4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

563040:SAUT RS09310
gene id: 563040:SAUT_RS09310
uniprot id: E0UQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

563040:SAUT RS06135
gene id: 563040:SAUT_RS06135
uniprot id: E0UT13
names: Similarity
messages: Belongs to the peptidase C40 family.

563040:SAUT RS03070
gene id: 563040:SAUT_RS03070
uniprot id: E0UPR6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS02425
gene id: 563040:SAUT_RS02425
uniprot id: E0UP69
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

563040:SAUT RS02045
gene id: 563040:SAUT_RS02045
uniprot id: E0UUU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

563040:SAUT RS08915
gene id: 563040:SAUT_RS08915
uniprot id: E0UQ57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

563040:SAUT RS01790
gene id: 563040:SAUT_RS01790
uniprot id: E0UUG7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS04400
gene id: 563040:SAUT_RS04400
uniprot id: E0UR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

563040:SAUT RS04870
gene id: 563040:SAUT_RS04870
uniprot id: E0URR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

563040:SAUT RS02745
gene id: 563040:SAUT_RS02745
uniprot id: E0UPK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

563040:SAUT RS08625
gene id: 563040:SAUT_RS08625
uniprot id: E0UPT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

563040:SAUT RS00985
gene id: 563040:SAUT_RS00985
uniprot id: E0UTL6
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

563040:SAUT RS01100
gene id: 563040:SAUT_RS01100
uniprot id: E0UTN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

563040:SAUT RS06275
gene id: 563040:SAUT_RS06275
uniprot id: E0UT43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

563040:SAUT RS03590
gene id: 563040:SAUT_RS03590
uniprot id: E0UQF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

563040:SAUT RS10880
gene id: 563040:SAUT_RS10880
uniprot id: E0US96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

563040:SAUT RS01295
gene id: 563040:SAUT_RS01295
uniprot id: E0UU01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

563040:SAUT RS02845
gene id: 563040:SAUT_RS02845
uniprot id: E0UPM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

563040:SAUT RS10860
gene id: 563040:SAUT_RS10860
uniprot id: E0US92
names: Similarity
messages: Belongs to the RecJ family.

563040:SAUT RS10780
gene id: 563040:SAUT_RS10780
uniprot id: E0US80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

563040:SAUT RS09295
gene id: 563040:SAUT_RS09295
uniprot id: E0UQK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

563040:SAUT RS00045
gene id: 563040:SAUT_RS00045
uniprot id: E0UP25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

563040:SAUT RS07360
gene id: 563040:SAUT_RS07360
uniprot id: E0UUC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

563040:SAUT RS06080
gene id: 563040:SAUT_RS06080
uniprot id: E0UT01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

563040:SAUT RS03575
gene id: 563040:SAUT_RS03575
uniprot id: E0UQF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

563040:SAUT RS09390
gene id: 563040:SAUT_RS09390
uniprot id: E0UQM4
names: Similarity
messages: Belongs to the bacterial secretin family.

563040:SAUT RS08930
gene id: 563040:SAUT_RS08930
uniprot id: E0UQ60
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

563040:SAUT RS09365
gene id: 563040:SAUT_RS09365
uniprot id: E0UQL9
names: Similarity
messages: Belongs to the GSP E family.

563040:SAUT RS05260
gene id: 563040:SAUT_RS05260
uniprot id: E0USB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

563040:SAUT RS02875
gene id: 563040:SAUT_RS02875
uniprot id: E0UPM8
names: Similarity
messages: Belongs to the TrpF family.

563040:SAUT RS10690
gene id: 563040:SAUT_RS10690
uniprot id: E0US61
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

563040:SAUT RS04055
gene id: 563040:SAUT_RS04055
uniprot id: E0UQW5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

563040:SAUT RS08385
gene id: 563040:SAUT_RS08385
uniprot id: E0UPH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

563040:SAUT RS07745
gene id: 563040:SAUT_RS07745
uniprot id: E0UUS4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

563040:SAUT RS09340
gene id: 563040:SAUT_RS09340
uniprot id: E0UQL4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

563040:SAUT RS01110
gene id: 563040:SAUT_RS01110
uniprot id: E0UTP1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

563040:SAUT RS01150
gene id: 563040:SAUT_RS01150
uniprot id: E0UTP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

563040:SAUT RS01820
gene id: 563040:SAUT_RS01820
uniprot id: E0UUH4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

563040:SAUT RS06630
gene id: 563040:SAUT_RS06630
uniprot id: E0UTJ2
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

563040:SAUT RS01605
gene id: 563040:SAUT_RS01605
uniprot id: E0UU57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

563040:SAUT RS06055
gene id: 563040:SAUT_RS06055
uniprot id: E0USZ6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

563040:SAUT RS06665
gene id: 563040:SAUT_RS06665
uniprot id: E0UTJ9
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS03965
gene id: 563040:SAUT_RS03965
uniprot id: E0UQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

563040:SAUT RS02465
gene id: 563040:SAUT_RS02465
uniprot id: E0UP77
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS02340
gene id: 563040:SAUT_RS02340
uniprot id: E0UV04
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

563040:SAUT RS07810
gene id: 563040:SAUT_RS07810
uniprot id: E0UV10
names: Similarity
messages: Belongs to the DEAD box helicase family.

563040:SAUT RS01275
gene id: 563040:SAUT_RS01275
uniprot id: E0UTZ7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

563040:SAUT RS03600
gene id: 563040:SAUT_RS03600
uniprot id: E0UQF5
names: Similarity
messages: Belongs to the peptidase S49 family.

563040:SAUT RS01210
gene id: 563040:SAUT_RS01210
uniprot id: E0UTR1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

563040:SAUT RS03345
gene id: 563040:SAUT_RS03345
uniprot id: E0UQ34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

563040:SAUT RS06475
gene id: 563040:SAUT_RS06475
uniprot id: E0UTG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

563040:SAUT RS06340
gene id: 563040:SAUT_RS06340
uniprot id: E0UTD4
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

563040:SAUT RS00015
gene id: 563040:SAUT_RS00015
uniprot id: E0UP19
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

563040:SAUT RS07330
gene id: 563040:SAUT_RS07330
uniprot id: E0UUC2
names: Subcellular Location Annotation
messages: Cytoplasm

563040:SAUT RS03990
gene id: 563040:SAUT_RS03990
uniprot id: E0UQV2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

563040:SAUT RS10905
gene id: 563040:SAUT_RS10905
uniprot id: E0USA1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

563040:SAUT RS10755
gene id: 563040:SAUT_RS10755
uniprot id: E0US75
names: Caution
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS02670
gene id: 563040:SAUT_RS02670
uniprot id: E0UPB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS05100
gene id: 563040:SAUT_RS05100
uniprot id: E0US27
names: Similarity
messages: Belongs to the DEAD box helicase family.

563040:SAUT RS04170
gene id: 563040:SAUT_RS04170
uniprot id: E0UQY2
names: Similarity
messages: Belongs to the threonine synthase family.

563040:SAUT RS04475
gene id: 563040:SAUT_RS04475
uniprot id: E0URB4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

563040:SAUT RS02310
gene id: 563040:SAUT_RS02310
uniprot id: E0UUZ8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

563040:SAUT RS00600
gene id: 563040:SAUT_RS00600
uniprot id: E0UT66
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

563040:SAUT RS08250
gene id: 563040:SAUT_RS08250
uniprot id: E0UPE6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

563040:SAUT RS06465
gene id: 563040:SAUT_RS06465
uniprot id: E0UTF9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS00010
gene id: 563040:SAUT_RS00010
uniprot id: E0UP18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

563040:SAUT RS06440
gene id: 563040:SAUT_RS06440
uniprot id: E0UTF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

563040:SAUT RS08655
gene id: 563040:SAUT_RS08655
uniprot id: E0UPU5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

563040:SAUT RS02740
gene id: 563040:SAUT_RS02740
uniprot id: E0UPK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.

563040:SAUT RS06165
gene id: 563040:SAUT_RS06165
uniprot id: E0UT20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

563040:SAUT RS01460
gene id: 563040:SAUT_RS01460
uniprot id: E0UU33
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

563040:SAUT RS05770
gene id: 563040:SAUT_RS05770
uniprot id: E0USL6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS01205
gene id: 563040:SAUT_RS01205
uniprot id: E0UTR0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

563040:SAUT RS02675
gene id: 563040:SAUT_RS02675
uniprot id: E0UPB9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

563040:SAUT RS02555
gene id: 563040:SAUT_RS02555
uniprot id: E0UP95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

563040:SAUT RS05750
gene id: 563040:SAUT_RS05750
uniprot id: E0USL2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.

563040:SAUT RS04945
gene id: 563040:SAUT_RS04945
uniprot id: E0URZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

563040:SAUT RS03980
gene id: 563040:SAUT_RS03980
uniprot id: E0UQV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

563040:SAUT RS01215
gene id: 563040:SAUT_RS01215
uniprot id: E0UTR2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

563040:SAUT RS06730
gene id: 563040:SAUT_RS06730
uniprot id: E0UTT3
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS10935
gene id: 563040:SAUT_RS10935
uniprot id: E0USA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

563040:SAUT RS00630
gene id: 563040:SAUT_RS00630
uniprot id: E0UT72
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

563040:SAUT RS10335
gene id: 563040:SAUT_RS10335
uniprot id: E0URR8
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS02880
gene id: 563040:SAUT_RS02880
uniprot id: E0UPM9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

563040:SAUT RS09070
gene id: 563040:SAUT_RS09070
uniprot id: E0UQ87
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

563040:SAUT RS07275
gene id: 563040:SAUT_RS07275
uniprot id: E0UUB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

563040:SAUT RS00490
gene id: 563040:SAUT_RS00490
uniprot id: E0USX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

563040:SAUT RS09155
gene id: 563040:SAUT_RS09155
uniprot id: E0UQA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

563040:SAUT RS02200
gene id: 563040:SAUT_RS02200
uniprot id: E0UUX5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

563040:SAUT RS01430
gene id: 563040:SAUT_RS01430
uniprot id: E0UU28
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS00710
gene id: 563040:SAUT_RS00710
uniprot id: E0UT88
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

563040:SAUT RS04485
gene id: 563040:SAUT_RS04485
uniprot id: E0URB6
names: Function
names: Similarity
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.

563040:SAUT RS08140
gene id: 563040:SAUT_RS08140
uniprot id: E0UV72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

563040:SAUT RS08770
gene id: 563040:SAUT_RS08770
uniprot id: E0UPW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

563040:SAUT RS10245
gene id: 563040:SAUT_RS10245
uniprot id: E0URH8
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

563040:SAUT RS07645
gene id: 563040:SAUT_RS07645
uniprot id: E0UUQ4
names: Similarity
messages: Belongs to the GPI family.

563040:SAUT RS06660
gene id: 563040:SAUT_RS06660
uniprot id: E0UTJ8
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS03245
gene id: 563040:SAUT_RS03245
uniprot id: E0UQ18
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

563040:SAUT RS11110
gene id: 563040:SAUT_RS11110
uniprot id: E0UQR1
names: PTM
messages: Binds 1 heme c group covalently per subunit.

563040:SAUT RS09260
gene id: 563040:SAUT_RS09260
uniprot id: E0UQJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

563040:SAUT RS00165
gene id: 563040:SAUT_RS00165
uniprot id: E0UP49
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

563040:SAUT RS01125
gene id: 563040:SAUT_RS01125
uniprot id: E0UTP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

563040:SAUT RS01625
gene id: 563040:SAUT_RS01625
uniprot id: E0UU61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

563040:SAUT RS01440
gene id: 563040:SAUT_RS01440
uniprot id: E0UU29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

563040:SAUT RS02400
gene id: 563040:SAUT_RS02400
uniprot id: E0UP64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

563040:SAUT RS05615
gene id: 563040:SAUT_RS05615
uniprot id: E0USI7
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS08335
gene id: 563040:SAUT_RS08335
uniprot id: E0UPG3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

563040:SAUT RS01370
gene id: 563040:SAUT_RS01370
uniprot id: E0UU16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

563040:SAUT RS10310
gene id: 563040:SAUT_RS10310
uniprot id: E0URR3
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS07095
gene id: 563040:SAUT_RS07095
uniprot id: E0UU76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

563040:SAUT RS03310
gene id: 563040:SAUT_RS03310
uniprot id: E0UQ31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

563040:SAUT RS03420
gene id: 563040:SAUT_RS03420
uniprot id: E0UQ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

563040:SAUT RS07155
gene id: 563040:SAUT_RS07155
uniprot id: E0UU88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

563040:SAUT RS08405
gene id: 563040:SAUT_RS08405
uniprot id: E0UPH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS10845
gene id: 563040:SAUT_RS10845
uniprot id: E0US89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS04655
gene id: 563040:SAUT_RS04655
uniprot id: E0URL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

563040:SAUT RS08595
gene id: 563040:SAUT_RS08595
uniprot id: E0UPT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

563040:SAUT RS07120
gene id: 563040:SAUT_RS07120
uniprot id: E0UU81
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Membrane

563040:SAUT RS10975
gene id: 563040:SAUT_RS10975
uniprot id: E0UT77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

563040:SAUT RS01585
gene id: 563040:SAUT_RS01585
uniprot id: E0UU53
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

563040:SAUT RS05570
gene id: 563040:SAUT_RS05570
uniprot id: E0USH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

563040:SAUT RS01570
gene id: 563040:SAUT_RS01570
uniprot id: E0UU51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

563040:SAUT RS02615
gene id: 563040:SAUT_RS02615
uniprot id: E0UPA7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

563040:SAUT RS06350
gene id: 563040:SAUT_RS06350
uniprot id: E0UTD6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

563040:SAUT RS04525
gene id: 563040:SAUT_RS04525
uniprot id: E0URC4
names: Similarity
messages: Belongs to the TlyA family.

563040:SAUT RS02925
gene id: 563040:SAUT_RS02925
uniprot id: E0UPN8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

563040:SAUT RS03940
gene id: 563040:SAUT_RS03940
uniprot id: E0UQU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

563040:SAUT RS09585
gene id: 563040:SAUT_RS09585
uniprot id: E0UQR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

563040:SAUT RS10960
gene id: 563040:SAUT_RS10960
uniprot id: E0USB3
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

563040:SAUT RS09035
gene id: 563040:SAUT_RS09035
uniprot id: E0UQ80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

563040:SAUT RS07295
gene id: 563040:SAUT_RS07295
uniprot id: E0UUB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

563040:SAUT RS09740
gene id: 563040:SAUT_RS09740
uniprot id: E0UR10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

563040:SAUT RS10195
gene id: 563040:SAUT_RS10195
uniprot id: E0URG8
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

563040:SAUT RS03580
gene id: 563040:SAUT_RS03580
uniprot id: E0UQF1
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

563040:SAUT RS08345
gene id: 563040:SAUT_RS08345
uniprot id: E0UPG5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

563040:SAUT RS09090
gene id: 563040:SAUT_RS09090
uniprot id: E0UQ92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

563040:SAUT RS09240
gene id: 563040:SAUT_RS09240
uniprot id: E0UQC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

563040:SAUT RS08935
gene id: 563040:SAUT_RS08935
uniprot id: E0UQ61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

563040:SAUT RS10485
gene id: 563040:SAUT_RS10485
uniprot id: E0URU8
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS10360
gene id: 563040:SAUT_RS10360
uniprot id: E0URS3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

563040:SAUT RS05525
gene id: 563040:SAUT_RS05525
uniprot id: E0USH0
names: Similarity
messages: Belongs to the sigma-54 factor family.

563040:SAUT RS08155
gene id: 563040:SAUT_RS08155
uniprot id: E0UPC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

563040:SAUT RS09300
gene id: 563040:SAUT_RS09300
uniprot id: E0UQK5
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

563040:SAUT RS08735
gene id: 563040:SAUT_RS08735
uniprot id: E0UPW1
names: Subcellular Location Annotation
messages: Cytoplasm

563040:SAUT RS05600
gene id: 563040:SAUT_RS05600
uniprot id: E0USI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

563040:SAUT RS04535
gene id: 563040:SAUT_RS04535
uniprot id: E0URJ2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

563040:SAUT RS02865
gene id: 563040:SAUT_RS02865
uniprot id: E0UPM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

563040:SAUT RS04530
gene id: 563040:SAUT_RS04530
uniprot id: E0URJ1
names: Similarity
messages: Belongs to the ribF family.

563040:SAUT RS02610
gene id: 563040:SAUT_RS02610
uniprot id: E0UPA6
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS07435
gene id: 563040:SAUT_RS07435
uniprot id: E0UUL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

563040:SAUT RS04500
gene id: 563040:SAUT_RS04500
uniprot id: E0URB9
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS02620
gene id: 563040:SAUT_RS02620
uniprot id: E0UPA8
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

563040:SAUT RS06025
gene id: 563040:SAUT_RS06025
uniprot id: E0USZ0
names: Similarity
messages: Belongs to the DEAD box helicase family.

563040:SAUT RS10350
gene id: 563040:SAUT_RS10350
uniprot id: E0URS1
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS08085
gene id: 563040:SAUT_RS08085
uniprot id: E0UV61
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

563040:SAUT RS09115
gene id: 563040:SAUT_RS09115
uniprot id: E0UQ97
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

563040:SAUT RS03765
gene id: 563040:SAUT_RS03765
uniprot id: E0UQI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

563040:SAUT RS08660
gene id: 563040:SAUT_RS08660
uniprot id: E0UPU6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

563040:SAUT RS03645
gene id: 563040:SAUT_RS03645
uniprot id: E0UQG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

563040:SAUT RS03960
gene id: 563040:SAUT_RS03960
uniprot id: E0UQU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

563040:SAUT RS08240
gene id: 563040:SAUT_RS08240
uniprot id: E0UPE4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

563040:SAUT RS06075
gene id: 563040:SAUT_RS06075
uniprot id: E0UT00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS07125
gene id: 563040:SAUT_RS07125
uniprot id: E0UU82
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

563040:SAUT RS00105
gene id: 563040:SAUT_RS00105
uniprot id: E0UP37
names: Similarity
messages: Belongs to the bacterial secretin family.

563040:SAUT RS09725
gene id: 563040:SAUT_RS09725
uniprot id: E0UR07
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

563040:SAUT RS01735
gene id: 563040:SAUT_RS01735
uniprot id: E0UUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

563040:SAUT RS04025
gene id: 563040:SAUT_RS04025
uniprot id: E0UQV9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS02410
gene id: 563040:SAUT_RS02410
uniprot id: E0UP66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

563040:SAUT RS00290
gene id: 563040:SAUT_RS00290
uniprot id: E0USS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

563040:SAUT RS08255
gene id: 563040:SAUT_RS08255
uniprot id: E0UPE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

563040:SAUT RS08995
gene id: 563040:SAUT_RS08995
uniprot id: E0UQ73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

563040:SAUT RS05590
gene id: 563040:SAUT_RS05590
uniprot id: E0USI2
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

563040:SAUT RS03900
gene id: 563040:SAUT_RS03900
uniprot id: E0UQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

563040:SAUT RS08920
gene id: 563040:SAUT_RS08920
uniprot id: E0UQ58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

563040:SAUT RS02935
gene id: 563040:SAUT_RS02935
uniprot id: E0UPP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

563040:SAUT RS03355
gene id: 563040:SAUT_RS03355
uniprot id: E0UQ36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS05655
gene id: 563040:SAUT_RS05655
uniprot id: E0USJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

563040:SAUT RS01155
gene id: 563040:SAUT_RS01155
uniprot id: E0UTQ0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

563040:SAUT RS02430
gene id: 563040:SAUT_RS02430
uniprot id: E0UP70
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

563040:SAUT RS06230
gene id: 563040:SAUT_RS06230
uniprot id: E0UT33
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS01640
gene id: 563040:SAUT_RS01640
uniprot id: E0UU64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

563040:SAUT RS07180
gene id: 563040:SAUT_RS07180
uniprot id: E0UU93
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS06480
gene id: 563040:SAUT_RS06480
uniprot id: E0UTG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

563040:SAUT RS09570
gene id: 563040:SAUT_RS09570
uniprot id: E0UQR0
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

563040:SAUT RS00085
gene id: 563040:SAUT_RS00085
uniprot id: E0UP33
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

563040:SAUT RS06930
gene id: 563040:SAUT_RS06930
uniprot id: E0UTX3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

563040:SAUT RS05815
gene id: 563040:SAUT_RS05815
uniprot id: E0USM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

563040:SAUT RS06925
gene id: 563040:SAUT_RS06925
uniprot id: E0UTX2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

563040:SAUT RS00175
gene id: 563040:SAUT_RS00175
uniprot id: E0UP51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

563040:SAUT RS11035
gene id: 563040:SAUT_RS11035
uniprot id: E0US04
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

563040:SAUT RS09270
gene id: 563040:SAUT_RS09270
uniprot id: E0UQJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

563040:SAUT RS01765
gene id: 563040:SAUT_RS01765
uniprot id: E0UUG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

563040:SAUT RS02805
gene id: 563040:SAUT_RS02805
uniprot id: E0UPL6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

563040:SAUT RS03385
gene id: 563040:SAUT_RS03385
uniprot id: E0UQ42
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

563040:SAUT RS06505
gene id: 563040:SAUT_RS06505
uniprot id: E0UTG7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS07720
gene id: 563040:SAUT_RS07720
uniprot id: E0UUR9
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS02350
gene id: 563040:SAUT_RS02350
uniprot id: E0UP54
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

563040:SAUT RS09200
gene id: 563040:SAUT_RS09200
uniprot id: E0UQB4
names: Similarity
messages: Belongs to the thioredoxin family.

563040:SAUT RS03610
gene id: 563040:SAUT_RS03610
uniprot id: E0UQF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

563040:SAUT RS00810
gene id: 563040:SAUT_RS00810
uniprot id: E0UTA8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

563040:SAUT RS01240
gene id: 563040:SAUT_RS01240
uniprot id: E0UTR7
names: Similarity
messages: Belongs to the nitroreductase family.

563040:SAUT RS01105
gene id: 563040:SAUT_RS01105
uniprot id: E0UTP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

563040:SAUT RS10025
gene id: 563040:SAUT_RS10025
uniprot id: E0URD7
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS01655
gene id: 563040:SAUT_RS01655
uniprot id: E0UUE0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

563040:SAUT RS03555
gene id: 563040:SAUT_RS03555
uniprot id: E0UQE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

563040:SAUT RS02565
gene id: 563040:SAUT_RS02565
uniprot id: E0UP97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

563040:SAUT RS02655
gene id: 563040:SAUT_RS02655
uniprot id: E0UPB5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

563040:SAUT RS09650
gene id: 563040:SAUT_RS09650
uniprot id: E0UQZ2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

563040:SAUT RS07135
gene id: 563040:SAUT_RS07135
uniprot id: E0UU84
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

563040:SAUT RS05660
gene id: 563040:SAUT_RS05660
uniprot id: E0USJ5
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS07855
gene id: 563040:SAUT_RS07855
uniprot id: E0UV19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

563040:SAUT RS03820
gene id: 563040:SAUT_RS03820
uniprot id: E0UQR8
names: Similarity
messages: Belongs to the TrpC family.

563040:SAUT RS04150
gene id: 563040:SAUT_RS04150
uniprot id: E0UQX8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS04785
gene id: 563040:SAUT_RS04785
uniprot id: E0URP3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

563040:SAUT RS04675
gene id: 563040:SAUT_RS04675
uniprot id: E0URM1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

563040:SAUT RS08310
gene id: 563040:SAUT_RS08310
uniprot id: E0UPF8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

563040:SAUT RS07825
gene id: 563040:SAUT_RS07825
uniprot id: E0UV13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

563040:SAUT RS06560
gene id: 563040:SAUT_RS06560
uniprot id: E0UTH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

563040:SAUT RS02780
gene id: 563040:SAUT_RS02780
uniprot id: E0UPL1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

563040:SAUT RS04140
gene id: 563040:SAUT_RS04140
uniprot id: E0UQX6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

563040:SAUT RS01870
gene id: 563040:SAUT_RS01870
uniprot id: E0UUI4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

563040:SAUT RS06605
gene id: 563040:SAUT_RS06605
uniprot id: E0UTI7
names: Similarity
messages: Belongs to the HupF/HypC family.

563040:SAUT RS01885
gene id: 563040:SAUT_RS01885
uniprot id: E0UUI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

563040:SAUT RS05065
gene id: 563040:SAUT_RS05065
uniprot id: E0US20
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

563040:SAUT RS00245
gene id: 563040:SAUT_RS00245
uniprot id: E0USS0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

563040:SAUT RS04470
gene id: 563040:SAUT_RS04470
uniprot id: E0URB3
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

563040:SAUT RS08410
gene id: 563040:SAUT_RS08410
uniprot id: E0UPH7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS03270
gene id: 563040:SAUT_RS03270
uniprot id: E0UQ23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS06595
gene id: 563040:SAUT_RS06595
uniprot id: E0UTI5
names: Similarity
messages: Belongs to the HypE family.

563040:SAUT RS07585
gene id: 563040:SAUT_RS07585
uniprot id: E0UUP3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

563040:SAUT RS00210
gene id: 563040:SAUT_RS00210
uniprot id: E0USR3
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

563040:SAUT RS07690
gene id: 563040:SAUT_RS07690
uniprot id: E0UUR3
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

563040:SAUT RS07070
gene id: 563040:SAUT_RS07070
uniprot id: E0UU71
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS02530
gene id: 563040:SAUT_RS02530
uniprot id: E0UP90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

563040:SAUT RS02445
gene id: 563040:SAUT_RS02445
uniprot id: E0UP73
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

563040:SAUT RS09345
gene id: 563040:SAUT_RS09345
uniprot id: E0UQL5
names: Similarity
messages: Belongs to the peptidase A24 family.

563040:SAUT RS03945
gene id: 563040:SAUT_RS03945
uniprot id: E0UQU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

563040:SAUT RS07715
gene id: 563040:SAUT_RS07715
uniprot id: E0UUR8
names: Caution
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS03920
gene id: 563040:SAUT_RS03920
uniprot id: E0UQT8
names: Similarity
messages: Belongs to the ParB family.

563040:SAUT RS03955
gene id: 563040:SAUT_RS03955
uniprot id: E0UQU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

563040:SAUT RS08540
gene id: 563040:SAUT_RS08540
uniprot id: E0UPS2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).

563040:SAUT RS09540
gene id: 563040:SAUT_RS09540
uniprot id: E0UQQ4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

563040:SAUT RS04585
gene id: 563040:SAUT_RS04585
uniprot id: E0URK2
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

563040:SAUT RS04350
gene id: 563040:SAUT_RS04350
uniprot id: E0UR90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

563040:SAUT RS08245
gene id: 563040:SAUT_RS08245
uniprot id: E0UPE5
names: Similarity
messages: Belongs to the peptidase S41A family.

563040:SAUT RS08860
gene id: 563040:SAUT_RS08860
uniprot id: E0UPY3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

563040:SAUT RS08645
gene id: 563040:SAUT_RS08645
uniprot id: E0UPU3
names: Similarity
messages: Belongs to the DprA/Smf family.

563040:SAUT RS04465
gene id: 563040:SAUT_RS04465
uniprot id: E0URB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

563040:SAUT RS10745
gene id: 563040:SAUT_RS10745
uniprot id: E0US73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS00335
gene id: 563040:SAUT_RS00335
uniprot id: E0UST6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

563040:SAUT RS03400
gene id: 563040:SAUT_RS03400
uniprot id: E0UQ45
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS08360
gene id: 563040:SAUT_RS08360
uniprot id: E0UPG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

563040:SAUT RS06775
gene id: 563040:SAUT_RS06775
uniprot id: E0UTU2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

563040:SAUT RS07515
gene id: 563040:SAUT_RS07515
uniprot id: E0UUM9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

563040:SAUT RS06420
gene id: 563040:SAUT_RS06420
uniprot id: E0UTF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

563040:SAUT RS04180
gene id: 563040:SAUT_RS04180
uniprot id: E0UR55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

563040:SAUT RS03290
gene id: 563040:SAUT_RS03290
uniprot id: E0UQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

563040:SAUT RS02695
gene id: 563040:SAUT_RS02695
uniprot id: E0UPC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

563040:SAUT RS07060
gene id: 563040:SAUT_RS07060
uniprot id: E0UU69
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

563040:SAUT RS03890
gene id: 563040:SAUT_RS03890
uniprot id: E0UQT2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

563040:SAUT RS07260
gene id: 563040:SAUT_RS07260
uniprot id: E0UUA8
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

563040:SAUT RS08380
gene id: 563040:SAUT_RS08380
uniprot id: E0UPH2
names: Similarity
messages: Belongs to the GSP E family.

563040:SAUT RS09620
gene id: 563040:SAUT_RS09620
uniprot id: E0UQY6
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS07650
gene id: 563040:SAUT_RS07650
uniprot id: E0UUQ5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

563040:SAUT RS06235
gene id: 563040:SAUT_RS06235
uniprot id: E0UT34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

563040:SAUT RS10965
gene id: 563040:SAUT_RS10965
uniprot id: E0USB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

563040:SAUT RS08350
gene id: 563040:SAUT_RS08350
uniprot id: E0UPG6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

563040:SAUT RS09190
gene id: 563040:SAUT_RS09190
uniprot id: E0UQB2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

563040:SAUT RS08630
gene id: 563040:SAUT_RS08630
uniprot id: E0UPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatB family.
messages: Cell inner membrane

563040:SAUT RS09995
gene id: 563040:SAUT_RS09995
uniprot id: E0URD1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

563040:SAUT RS07395
gene id: 563040:SAUT_RS07395
uniprot id: E0UUD5
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS08580
gene id: 563040:SAUT_RS08580
uniprot id: E0UPT0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

563040:SAUT RS09775
gene id: 563040:SAUT_RS09775
uniprot id: E0UR17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

563040:SAUT RS08070
gene id: 563040:SAUT_RS08070
uniprot id: E0UV58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS10455
gene id: 563040:SAUT_RS10455
uniprot id: E0URU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

563040:SAUT RS00495
gene id: 563040:SAUT_RS00495
uniprot id: E0USX1
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

563040:SAUT RS02540
gene id: 563040:SAUT_RS02540
uniprot id: E0UP92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

563040:SAUT RS10750
gene id: 563040:SAUT_RS10750
uniprot id: E0US74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

563040:SAUT RS06085
gene id: 563040:SAUT_RS06085
uniprot id: E0UT02
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

563040:SAUT RS01495
gene id: 563040:SAUT_RS01495
uniprot id: E0UU40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

563040:SAUT RS07290
gene id: 563040:SAUT_RS07290
uniprot id: E0UUB4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

563040:SAUT RS06380
gene id: 563040:SAUT_RS06380
uniprot id: E0UTE2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

563040:SAUT RS10730
gene id: 563040:SAUT_RS10730
uniprot id: E0US70
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

563040:SAUT RS01035
gene id: 563040:SAUT_RS01035
uniprot id: E0UTM6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

563040:SAUT RS00580
gene id: 563040:SAUT_RS00580
uniprot id: E0UT62
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS07795
gene id: 563040:SAUT_RS07795
uniprot id: E0UV06
names: Similarity
messages: Belongs to the polypeptide deformylase family.

563040:SAUT RS08590
gene id: 563040:SAUT_RS08590
uniprot id: E0UPT2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

563040:SAUT RS08730
gene id: 563040:SAUT_RS08730
uniprot id: E0UPW0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS01020
gene id: 563040:SAUT_RS01020
uniprot id: E0UTM3
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

563040:SAUT RS00220
gene id: 563040:SAUT_RS00220
uniprot id: E0USR5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

563040:SAUT RS09470
gene id: 563040:SAUT_RS09470
uniprot id: E0UQP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

563040:SAUT RS02335
gene id: 563040:SAUT_RS02335
uniprot id: E0UV03
names: Similarity
messages: Belongs to the AdoMet synthase family.

563040:SAUT RS10560
gene id: 563040:SAUT_RS10560
uniprot id: E0URW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

563040:SAUT RS06975
gene id: 563040:SAUT_RS06975
uniprot id: E0UTY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

563040:SAUT RS10835
gene id: 563040:SAUT_RS10835
uniprot id: E0US87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

563040:SAUT RS00005
gene id: 563040:SAUT_RS00005
uniprot id: E0UP17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

563040:SAUT RS00075
gene id: 563040:SAUT_RS00075
uniprot id: E0UP31
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

563040:SAUT RS04645
gene id: 563040:SAUT_RS04645
uniprot id: E0URL5
names: Similarity
messages: Belongs to the UbiD family.

563040:SAUT RS01875
gene id: 563040:SAUT_RS01875
uniprot id: E0UUI5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

563040:SAUT RS05695
gene id: 563040:SAUT_RS05695
uniprot id: E0USK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

563040:SAUT RS00560
gene id: 563040:SAUT_RS00560
uniprot id: E0UT58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

563040:SAUT RS06305
gene id: 563040:SAUT_RS06305
uniprot id: E0UT51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

563040:SAUT RS01665
gene id: 563040:SAUT_RS01665
uniprot id: E0UUE2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

563040:SAUT RS01650
gene id: 563040:SAUT_RS01650
uniprot id: E0UUD9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

563040:SAUT RS09460
gene id: 563040:SAUT_RS09460
uniprot id: E0UQN8
names: Similarity
messages: Belongs to the PstS family.

563040:SAUT RS10830
gene id: 563040:SAUT_RS10830
uniprot id: E0US86
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

563040:SAUT RS05860
gene id: 563040:SAUT_RS05860
uniprot id: E0USN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

563040:SAUT RS01120
gene id: 563040:SAUT_RS01120
uniprot id: E0UTP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

563040:SAUT RS10805
gene id: 563040:SAUT_RS10805
uniprot id: E0US81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

563040:SAUT RS03160
gene id: 563040:SAUT_RS03160
uniprot id: E0UQ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

563040:SAUT RS00410
gene id: 563040:SAUT_RS00410
uniprot id: E0USV1
names: Similarity
messages: Belongs to the polypeptide deformylase family.

563040:SAUT RS01080
gene id: 563040:SAUT_RS01080
uniprot id: E0UTN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

563040:SAUT RS00255
gene id: 563040:SAUT_RS00255
uniprot id: E0USS2
names: Similarity
messages: Belongs to the UPF0234 family.

563040:SAUT RS08455
gene id: 563040:SAUT_RS08455
uniprot id: E0UPI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

563040:SAUT RS06740
gene id: 563040:SAUT_RS06740
uniprot id: E0UTT5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

563040:SAUT RS07625
gene id: 563040:SAUT_RS07625
uniprot id: E0UUQ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS07830
gene id: 563040:SAUT_RS07830
uniprot id: E0UV14
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

563040:SAUT RS06180
gene id: 563040:SAUT_RS06180
uniprot id: E0UT23
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

563040:SAUT RS08985
gene id: 563040:SAUT_RS08985
uniprot id: E0UQ71
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

563040:SAUT RS05560
gene id: 563040:SAUT_RS05560
uniprot id: E0USH6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

563040:SAUT RS04700
gene id: 563040:SAUT_RS04700
uniprot id: E0URM6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

563040:SAUT RS04620
gene id: 563040:SAUT_RS04620
uniprot id: E0URL0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

563040:SAUT RS03545
gene id: 563040:SAUT_RS03545
uniprot id: E0UQE5
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

563040:SAUT RS04930
gene id: 563040:SAUT_RS04930
uniprot id: E0URZ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

563040:SAUT RS06855
gene id: 563040:SAUT_RS06855
uniprot id: E0UTV8
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

563040:SAUT RS05605
gene id: 563040:SAUT_RS05605
uniprot id: E0USI5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

563040:SAUT RS05030
gene id: 563040:SAUT_RS05030
uniprot id: E0US13
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS06920
gene id: 563040:SAUT_RS06920
uniprot id: E0UTX1
names: Subcellular Location Annotation
messages: Mitochondrion

563040:SAUT RS01140
gene id: 563040:SAUT_RS01140
uniprot id: E0UTP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

563040:SAUT RS08815
gene id: 563040:SAUT_RS08815
uniprot id: E0UPX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

563040:SAUT RS00635
gene id: 563040:SAUT_RS00635
uniprot id: E0UT73
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

563040:SAUT RS08270
gene id: 563040:SAUT_RS08270
uniprot id: E0UPF0
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

563040:SAUT RS02395
gene id: 563040:SAUT_RS02395
uniprot id: E0UP63
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

563040:SAUT RS09680
gene id: 563040:SAUT_RS09680
uniprot id: E0UQZ8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

563040:SAUT RS03830
gene id: 563040:SAUT_RS03830
uniprot id: E0UQS0
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Homodimer.

563040:SAUT RS01450
gene id: 563040:SAUT_RS01450
uniprot id: E0UU31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

563040:SAUT RS09765
gene id: 563040:SAUT_RS09765
uniprot id: E0UR15
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

563040:SAUT RS06150
gene id: 563040:SAUT_RS06150
uniprot id: E0UT17
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

563040:SAUT RS08365
gene id: 563040:SAUT_RS08365
uniprot id: E0UPG9
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS00845
gene id: 563040:SAUT_RS00845
uniprot id: E0UTB7
names: Similarity
messages: Belongs to the HsdR family.

563040:SAUT RS02930
gene id: 563040:SAUT_RS02930
uniprot id: E0UPN9
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS06205
gene id: 563040:SAUT_RS06205
uniprot id: E0UT28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

563040:SAUT RS06370
gene id: 563040:SAUT_RS06370
uniprot id: E0UTE0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

563040:SAUT RS07040
gene id: 563040:SAUT_RS07040
uniprot id: E0UTZ6
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS01800
gene id: 563040:SAUT_RS01800
uniprot id: E0UUG9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

563040:SAUT RS08500
gene id: 563040:SAUT_RS08500
uniprot id: E0UPJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

563040:SAUT RS02110
gene id: 563040:SAUT_RS02110
uniprot id: E0UUV6
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS05550
gene id: 563040:SAUT_RS05550
uniprot id: E0USH4
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

563040:SAUT RS08715
gene id: 563040:SAUT_RS08715
uniprot id: E0UPV7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

563040:SAUT RS05515
gene id: 563040:SAUT_RS05515
uniprot id: E0USG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

563040:SAUT RS07630
gene id: 563040:SAUT_RS07630
uniprot id: E0UUQ2
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

563040:SAUT RS09440
gene id: 563040:SAUT_RS09440
uniprot id: E0UQN4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

563040:SAUT RS03060
gene id: 563040:SAUT_RS03060
uniprot id: E0UPR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

563040:SAUT RS10580
gene id: 563040:SAUT_RS10580
uniprot id: E0URW7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

563040:SAUT RS08135
gene id: 563040:SAUT_RS08135
uniprot id: E0UV71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

563040:SAUT RS07010
gene id: 563040:SAUT_RS07010
uniprot id: E0UTZ0
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS01725
gene id: 563040:SAUT_RS01725
uniprot id: E0UUF4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

563040:SAUT RS10840
gene id: 563040:SAUT_RS10840
uniprot id: E0US88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

563040:SAUT RS02665
gene id: 563040:SAUT_RS02665
uniprot id: E0UPB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

563040:SAUT RS02580
gene id: 563040:SAUT_RS02580
uniprot id: E0UPA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

563040:SAUT RS08375
gene id: 563040:SAUT_RS08375
uniprot id: E0UPH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

563040:SAUT RS09875
gene id: 563040:SAUT_RS09875
uniprot id: E0UR37
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

563040:SAUT RS00515
gene id: 563040:SAUT_RS00515
uniprot id: E0USX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

563040:SAUT RS07470
gene id: 563040:SAUT_RS07470
uniprot id: E0UUM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

563040:SAUT RS01965
gene id: 563040:SAUT_RS01965
uniprot id: E0UUK3
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS08275
gene id: 563040:SAUT_RS08275
uniprot id: E0UPF1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

563040:SAUT RS09320
gene id: 563040:SAUT_RS09320
uniprot id: E0UQK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

563040:SAUT RS05405
gene id: 563040:SAUT_RS05405
uniprot id: E0USE6
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

563040:SAUT RS03620
gene id: 563040:SAUT_RS03620
uniprot id: E0UQG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

563040:SAUT RS04755
gene id: 563040:SAUT_RS04755
uniprot id: E0URN7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

563040:SAUT RS07455
gene id: 563040:SAUT_RS07455
uniprot id: E0UUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

563040:SAUT RS05145
gene id: 563040:SAUT_RS05145
uniprot id: E0US36
names: Similarity
messages: Belongs to the peptidase M18 family.

563040:SAUT RS07225
gene id: 563040:SAUT_RS07225
uniprot id: E0UUA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

563040:SAUT RS00620
gene id: 563040:SAUT_RS00620
uniprot id: E0UT70
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS10925
gene id: 563040:SAUT_RS10925
uniprot id: E0USA6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

563040:SAUT RS05385
gene id: 563040:SAUT_RS05385
uniprot id: E0USE2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

563040:SAUT RS03795
gene id: 563040:SAUT_RS03795
uniprot id: E0UQJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

563040:SAUT RS03130
gene id: 563040:SAUT_RS03130
uniprot id: E0UPZ5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

563040:SAUT RS05680
gene id: 563040:SAUT_RS05680
uniprot id: E0USJ9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

563040:SAUT RS07160
gene id: 563040:SAUT_RS07160
uniprot id: E0UU89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

563040:SAUT RS09195
gene id: 563040:SAUT_RS09195
uniprot id: E0UQB3
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

563040:SAUT RS10235
gene id: 563040:SAUT_RS10235
uniprot id: E0URH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

563040:SAUT RS10105
gene id: 563040:SAUT_RS10105
uniprot id: E0URF3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS10215
gene id: 563040:SAUT_RS10215
uniprot id: E0URH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

563040:SAUT RS09710
gene id: 563040:SAUT_RS09710
uniprot id: E0UR04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

563040:SAUT RS02050
gene id: 563040:SAUT_RS02050
uniprot id: E0UUU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

563040:SAUT RS07960
gene id: 563040:SAUT_RS07960
uniprot id: E0UV40
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

563040:SAUT RS00625
gene id: 563040:SAUT_RS00625
uniprot id: E0UT71
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

563040:SAUT RS04545
gene id: 563040:SAUT_RS04545
uniprot id: E0URJ4
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS04790
gene id: 563040:SAUT_RS04790
uniprot id: E0URP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

563040:SAUT RS02235
gene id: 563040:SAUT_RS02235
uniprot id: E0UUY3
names: Similarity
messages: Belongs to the GSP E family.

563040:SAUT RS04735
gene id: 563040:SAUT_RS04735
uniprot id: E0URN3
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS02205
gene id: 563040:SAUT_RS02205
uniprot id: E0UUX6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

563040:SAUT RS06690
gene id: 563040:SAUT_RS06690
uniprot id: E0UTS5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

563040:SAUT RS00380
gene id: 563040:SAUT_RS00380
uniprot id: E0USU5
names: Subcellular Location Annotation
messages: Membrane

563040:SAUT RS08945
gene id: 563040:SAUT_RS08945
uniprot id: E0UQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

563040:SAUT RS06635
gene id: 563040:SAUT_RS06635
uniprot id: E0UTJ3
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

563040:SAUT RS00235
gene id: 563040:SAUT_RS00235
uniprot id: E0USR8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

563040:SAUT RS08810
gene id: 563040:SAUT_RS08810
uniprot id: E0UPX5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

563040:SAUT RS09325
gene id: 563040:SAUT_RS09325
uniprot id: E0UQL0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

563040:SAUT RS03675
gene id: 563040:SAUT_RS03675
uniprot id: E0UQG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

563040:SAUT RS01610
gene id: 563040:SAUT_RS01610
uniprot id: E0UU58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

563040:SAUT RS00540
gene id: 563040:SAUT_RS00540
uniprot id: E0USY0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

563040:SAUT RS08865
gene id: 563040:SAUT_RS08865
uniprot id: E0UPY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

563040:SAUT RS01160
gene id: 563040:SAUT_RS01160
uniprot id: E0UTQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

563040:SAUT RS09815
gene id: 563040:SAUT_RS09815
uniprot id: E0UR25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

563040:SAUT RS05325
gene id: 563040:SAUT_RS05325
uniprot id: E0USD0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

563040:SAUT RS02895
gene id: 563040:SAUT_RS02895
uniprot id: E0UPN2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

563040:SAUT RS07465
gene id: 563040:SAUT_RS07465
uniprot id: E0UUL9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

563040:SAUT RS01580
gene id: 563040:SAUT_RS01580
uniprot id: E0UU52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

563040:SAUT RS00725
gene id: 563040:SAUT_RS00725
uniprot id: E0UT91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

563040:SAUT RS09795
gene id: 563040:SAUT_RS09795
uniprot id: E0UR21
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

563040:SAUT RS10670
gene id: 563040:SAUT_RS10670
uniprot id: E0US57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

563040:SAUT RS07050
gene id: 563040:SAUT_RS07050
uniprot id: E0UU67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

563040:SAUT RS07615
gene id: 563040:SAUT_RS07615
uniprot id: E0UUP9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

563040:SAUT RS00720
gene id: 563040:SAUT_RS00720
uniprot id: E0UT90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

563040:SAUT RS02230
gene id: 563040:SAUT_RS02230
uniprot id: E0UUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

563040:SAUT RS03195
gene id: 563040:SAUT_RS03195
uniprot id: E0UQ08
names: Similarity
messages: Belongs to the SUI1 family.

563040:SAUT RS06170
gene id: 563040:SAUT_RS06170
uniprot id: E0UT21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

563040:SAUT RS08615
gene id: 563040:SAUT_RS08615
uniprot id: E0UPT7
names: Similarity
messages: Belongs to the aspartokinase family.

563040:SAUT RS06460
gene id: 563040:SAUT_RS06460
uniprot id: E0UTF8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

563040:SAUT RS01320
gene id: 563040:SAUT_RS01320
uniprot id: E0UU06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

563040:SAUT RS04600
gene id: 563040:SAUT_RS04600
uniprot id: E0URK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

563040:SAUT RS09100
gene id: 563040:SAUT_RS09100
uniprot id: E0UQ94
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS05780
gene id: 563040:SAUT_RS05780
uniprot id: E0USL8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS07445
gene id: 563040:SAUT_RS07445
uniprot id: E0UUL5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

563040:SAUT RS06290
gene id: 563040:SAUT_RS06290
uniprot id: E0UT48
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

563040:SAUT RS08975
gene id: 563040:SAUT_RS08975
uniprot id: E0UQ69
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

563040:SAUT RS02585
gene id: 563040:SAUT_RS02585
uniprot id: E0UPA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

563040:SAUT RS04615
gene id: 563040:SAUT_RS04615
uniprot id: E0URK9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

563040:SAUT RS09025
gene id: 563040:SAUT_RS09025
uniprot id: E0UQ79
names: Similarity
messages: Belongs to the UPF0178 family.

563040:SAUT RS03315
gene id: 563040:SAUT_RS03315
uniprot id: E0UQ32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

563040:SAUT RS01785
gene id: 563040:SAUT_RS01785
uniprot id: E0UUG6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

563040:SAUT RS04405
gene id: 563040:SAUT_RS04405
uniprot id: E0URA0
names: Similarity
messages: Belongs to the IMPACT family.

563040:SAUT RS00460
gene id: 563040:SAUT_RS00460
uniprot id: E0USW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

563040:SAUT RS07375
gene id: 563040:SAUT_RS07375
uniprot id: E0UUD1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

563040:SAUT RS00340
gene id: 563040:SAUT_RS00340
uniprot id: E0UST7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

563040:SAUT RS05635
gene id: 563040:SAUT_RS05635
uniprot id: E0USJ0
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

563040:SAUT RS03905
gene id: 563040:SAUT_RS03905
uniprot id: E0UQT5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

563040:SAUT RS02115
gene id: 563040:SAUT_RS02115
uniprot id: E0UUV7
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

563040:SAUT RS02105
gene id: 563040:SAUT_RS02105
uniprot id: E0UUV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

563040:SAUT RS01015
gene id: 563040:SAUT_RS01015
uniprot id: E0UTM2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

563040:SAUT RS06525
gene id: 563040:SAUT_RS06525
uniprot id: E0UTH1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

563040:SAUT RS02010
gene id: 563040:SAUT_RS02010
uniprot id: E0UUT6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

563040:SAUT RS09150
gene id: 563040:SAUT_RS09150
uniprot id: E0UQA4
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

563040:SAUT RS06070
gene id: 563040:SAUT_RS06070
uniprot id: E0USZ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.