55661:CLCN4
gene id: 55661:CLCN4
uniprot id: A0A091FTG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

55661:CACNB2
gene id: 55661:CACNB2
uniprot id: A0A091FX10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: sarcolemma

55661:CLDN20
gene id: 55661:CLDN20
uniprot id: A0A091FP58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

55661:MAPK6
gene id: 55661:MAPK6
uniprot id: A0A091FT94
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

55661:EPYC
gene id: 55661:EPYC
uniprot id: A0A091G2C6
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

55661:CD40LG
gene id: 55661:CD40LG
uniprot id: A0A091G608
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

55661:LOC104058165
gene id: 55661:LOC104058165
uniprot id: A0A091G1D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

55661:GTF2A2
gene id: 55661:GTF2A2
uniprot id: A0A091FS88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

55661:GNB3
gene id: 55661:GNB3
uniprot id: A0A091GDL1
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

55661:SYNDIG1L
gene id: 55661:SYNDIG1L
uniprot id: A0A091GVT4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

55661:CEP76
gene id: 55661:CEP76
uniprot id: A0A091GGB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

55661:SLC25A10
gene id: 55661:SLC25A10
uniprot id: A0A091FZV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

55661:STX7
gene id: 55661:STX7
uniprot id: A0A091FZX0
names: Similarity
messages: Belongs to the syntaxin family.

55661:AVPR1B
gene id: 55661:AVPR1B
uniprot id: A0A091GWB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

55661:LOC104056762
gene id: 55661:LOC104056762
uniprot id: A0A091FY17
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

55661:NID1
gene id: 55661:NID1
uniprot id: A0A091G6Y3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

55661:GJA1
gene id: 55661:GJA1
uniprot id: A0A091FFB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

55661:SI
gene id: 55661:SI
uniprot id: A0A091GJ02
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

55661:CLP1
gene id: 55661:CLP1
uniprot id: A0A091G980
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

55661:POLR3D
gene id: 55661:POLR3D
uniprot id: A0A091FRD2
names: Subcellular Location Annotation
messages: Nucleus

55661:MLH1
gene id: 55661:MLH1
uniprot id: A0A091FJK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

55661:LOC104061352
gene id: 55661:LOC104061352
uniprot id: A0A091G7L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

55661:DNAAF4
gene id: 55661:DNAAF4
uniprot id: A0A091G7B0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Dynein axonemal particle
messages: neuron projection

55661:RPL27
gene id: 55661:RPL27
uniprot id: A0A091FSF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

55661:ZDHHC22
gene id: 55661:ZDHHC22
uniprot id: A0A091GDS2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

55661:SLC39A3
gene id: 55661:SLC39A3
uniprot id: A0A091H5Q2
names: Subcellular Location Annotation
messages: Membrane

55661:UTP23
gene id: 55661:UTP23
uniprot id: A0A091FM14
names: Subcellular Location Annotation
messages: nucleolus

55661:CLRN1
gene id: 55661:CLRN1
uniprot id: A0A091H4F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

55661:ISCA1
gene id: 55661:ISCA1
uniprot id: A0A091G454
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

55661:AIDA
gene id: 55661:AIDA
uniprot id: A0A091GN59
names: Similarity
messages: Belongs to the AIDA family.

55661:BRINP1
gene id: 55661:BRINP1
uniprot id: A0A091H834
names: Similarity
messages: Belongs to the BRINP family.

55661:FGF7
gene id: 55661:FGF7
uniprot id: A0A091FUD0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

55661:FN3K
gene id: 55661:FN3K
uniprot id: A0A091G384
names: Similarity
messages: Belongs to the fructosamine kinase family.

55661:MB
gene id: 55661:MB
uniprot id: A0A091H5V9
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

55661:ASF1A
gene id: 55661:ASF1A
uniprot id: A0A091G7M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

55661:KIN
gene id: 55661:KIN
uniprot id: A0A091G8J5
names: Similarity
messages: Belongs to the KIN17 family.

55661:SERPINF1
gene id: 55661:SERPINF1
uniprot id: A0A091G109
names: Similarity
messages: Belongs to the serpin family.

55661:TFB1M
gene id: 55661:TFB1M
uniprot id: A0A091FJS5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

55661:CALHM1
gene id: 55661:CALHM1
uniprot id: A0A091FIS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

55661:SFRP2
gene id: 55661:SFRP2
uniprot id: A0A091G879
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

55661:KHDRBS3
gene id: 55661:KHDRBS3
uniprot id: A0A091G0P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KHDRBS family.
messages: Cytoplasm

55661:LOC104068952
gene id: 55661:LOC104068952
uniprot id: A0A091FRR3
names: Similarity
messages: Belongs to the cytochrome P450 family.

55661:CLRN3
gene id: 55661:CLRN3
uniprot id: A0A091G806
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

55661:DLGAP1
gene id: 55661:DLGAP1
uniprot id: A0A091GG85
names: Similarity
messages: Belongs to the SAPAP family.

55661:BDNF
gene id: 55661:BDNF
uniprot id: A0A091FT70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
messages: Secreted

55661:PTGS2
gene id: 55661:PTGS2
uniprot id: A0A091GDT9
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

55661:RUNX3
gene id: 55661:RUNX3
uniprot id: A0A091GA44
names: Subcellular Location Annotation
messages: Nucleus

55661:C3H6orf120
gene id: 55661:C3H6orf120
uniprot id: A0A091H383
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

55661:LOC104065657
gene id: 55661:LOC104065657
uniprot id: A0A091GHR0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

55661:NUDT12
gene id: 55661:NUDT12
uniprot id: A0A091GMT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

55661:CLDN1
gene id: 55661:CLDN1
uniprot id: A0A091GBD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

55661:LOC104054910
gene id: 55661:LOC104054910
uniprot id: A0A091FSA6
names: Similarity
messages: Belongs to the cytochrome P450 family.

55661:MED13
gene id: 55661:MED13
uniprot id: A0A091H3Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

55661:BCL2A1
gene id: 55661:BCL2A1
uniprot id: A0A091G4B2
names: Similarity
messages: Belongs to the Bcl-2 family.

55661:IFT56
gene id: 55661:IFT56
uniprot id: A0A091FVK0
names: Similarity
messages: Belongs to the IFT56 family.

55661:ST8SIA4
gene id: 55661:ST8SIA4
uniprot id: A0A091G2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

55661:ADPRHL1
gene id: 55661:ADPRHL1
uniprot id: A0A091FXU5
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

55661:LOC104061435
gene id: 55661:LOC104061435
uniprot id: A0A091G9G5
names: Similarity
messages: Belongs to the peptidase M14 family.

55661:PRPH2
gene id: 55661:PRPH2
uniprot id: A0A091GLV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

55661:SPI1
gene id: 55661:SPI1
uniprot id: A0A091GKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

55661:ATF7IP
gene id: 55661:ATF7IP
uniprot id: A0A091FTQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

55661:CLDN2
gene id: 55661:CLDN2
uniprot id: A0A091FQQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

55661:HSPA4L
gene id: 55661:HSPA4L
uniprot id: A0A091GFD1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

55661:SLC34A2
gene id: 55661:SLC34A2
uniprot id: A0A091GZL4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

55661:RAG1
gene id: 55661:RAG1
uniprot id: A0A091FX46
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

55661:SAP18
gene id: 55661:SAP18
uniprot id: A0A091GFH7
names: Function
names: Similarity
messages: Belongs to the SAP18 family.
messages: Involved in the tethering of the SIN3 complex to core histone proteins.

55661:TNFSF13B
gene id: 55661:TNFSF13B
uniprot id: A0A091GBJ6
names: Similarity
messages: Belongs to the tumor necrosis factor family.

55661:HDLBP
gene id: 55661:HDLBP
uniprot id: A0A091GFQ7
names: Subcellular Location Annotation
messages: Cytoplasm

55661:GNL2
gene id: 55661:GNL2
uniprot id: A0A091GCB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

55661:METTL16
gene id: 55661:METTL16
uniprot id: A0A091GGU6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

55661:UNC93A
gene id: 55661:UNC93A
uniprot id: A0A091FTJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

55661:VGLL4
gene id: 55661:VGLL4
uniprot id: A0A091GH21
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

55661:CRY1
gene id: 55661:CRY1
uniprot id: A0A091FX31
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

55661:TFIP11
gene id: 55661:TFIP11
uniprot id: A0A091G3P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFP11/STIP family.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
messages: Nucleus

55661:ZDHHC21
gene id: 55661:ZDHHC21
uniprot id: A0A091FQL8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

55661:GGNBP2
gene id: 55661:GGNBP2
uniprot id: A0A091GG46
names: Function
messages: May be involved in spermatogenesis.

55661:FBLN5
gene id: 55661:FBLN5
uniprot id: A0A091GRD6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

55661:TLX1
gene id: 55661:TLX1
uniprot id: A0A091G244
names: Subcellular Location Annotation
messages: Nucleus

55661:SPC25
gene id: 55661:SPC25
uniprot id: A0A091FNY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

55661:ALDOB
gene id: 55661:ALDOB
uniprot id: A0A091GHX0
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

55661:UBE4A
gene id: 55661:UBE4A
uniprot id: A0A091FFQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

55661:CDPF1
gene id: 55661:CDPF1
uniprot id: A0A091GCU3
names: Similarity
messages: Belongs to the CDPF1 family.

55661:ATP6V1G3
gene id: 55661:ATP6V1G3
uniprot id: A0A091FTS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

55661:CDX1
gene id: 55661:CDX1
uniprot id: A0A091FLB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

55661:NDP
gene id: 55661:NDP
uniprot id: A0A091G4A0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

55661:MMP23B
gene id: 55661:MMP23B
uniprot id: A0A091FRI9
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

55661:SCG2
gene id: 55661:SCG2
uniprot id: A0A091GNU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

55661:MAP3K7
gene id: 55661:MAP3K7
uniprot id: A0A091FLF6
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

55661:TPI1
gene id: 55661:TPI1
uniprot id: A0A091GH11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

55661:TH
gene id: 55661:TH
uniprot id: A0A091FQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

55661:CLRN2
gene id: 55661:CLRN2
uniprot id: A0A091FJG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

55661:GRPR
gene id: 55661:GRPR
uniprot id: A0A091GE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

55661:HCRTR2
gene id: 55661:HCRTR2
uniprot id: A0A091GH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

55661:FGF6
gene id: 55661:FGF6
uniprot id: A0A091H7V5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

55661:CDK7
gene id: 55661:CDK7
uniprot id: A0A091GCQ4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

55661:RPLP1
gene id: 55661:RPLP1
uniprot id: A0A091GFX3
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

55661:CORT
gene id: 55661:CORT
uniprot id: A0A091G7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

55661:GDPD2
gene id: 55661:GDPD2
uniprot id: A0A091FIG9
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

55661:CCNL2
gene id: 55661:CCNL2
uniprot id: A0A091FVU9
names: Similarity
messages: Belongs to the cyclin family.

55661:TRAPPC11
gene id: 55661:TRAPPC11
uniprot id: A0A091GCM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPPC11 family.
messages: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
messages: cis-Golgi network

55661:MOGAT2
gene id: 55661:MOGAT2
uniprot id: A0A091GGJ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

55661:ACTR10
gene id: 55661:ACTR10
uniprot id: A0A091FVS9
names: Similarity
messages: Belongs to the actin family.

55661:YAF2
gene id: 55661:YAF2
uniprot id: A0A091GBX9
names: Subcellular Location Annotation
messages: Nucleus

55661:LOC104056241
gene id: 55661:LOC104056241
uniprot id: A0A091FWZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

55661:CSGALNACT1
gene id: 55661:CSGALNACT1
uniprot id: A0A091GH91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

55661:TRIAP1
gene id: 55661:TRIAP1
uniprot id: A0A091FMI8
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

55661:CHRM2
gene id: 55661:CHRM2
uniprot id: A0A091G495
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

55661:GMPR
gene id: 55661:GMPR
uniprot id: A0A091G9F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

55661:ASIC4
gene id: 55661:ASIC4
uniprot id: A0A091FNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

55661:IFNG
gene id: 55661:IFNG
uniprot id: A0A091FLR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II (or gamma) interferon family.
messages: Homodimer.
messages: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
messages: Secreted

55661:SPRING1
gene id: 55661:SPRING1
uniprot id: A0A091FWR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

55661:LOC104064687
gene id: 55661:LOC104064687
uniprot id: A0A091GEC8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

55661:EPB41
gene id: 55661:EPB41
uniprot id: A0A091G5F5
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex
messages: cytoskeleton

55661:TDO2
gene id: 55661:TDO2
uniprot id: A0A091GEG2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

55661:RFTN2
gene id: 55661:RFTN2
uniprot id: A0A091GJC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

55661:FSHB
gene id: 55661:FSHB
uniprot id: A0A091GFP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

55661:TINAG
gene id: 55661:TINAG
uniprot id: A0A091GFU1
names: Similarity
messages: Belongs to the peptidase C1 family.

55661:ACTG2
gene id: 55661:ACTG2
uniprot id: A0A091FNA0
names: Similarity
messages: Belongs to the actin family.

55661:WLS
gene id: 55661:WLS
uniprot id: A0A091GLU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

55661:NR2E3
gene id: 55661:NR2E3
uniprot id: A0A091GI68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

55661:HSPB7
gene id: 55661:HSPB7
uniprot id: A0A091FQA0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

55661:NOX3
gene id: 55661:NOX3
uniprot id: A0A091FNQ1
names: Subcellular Location Annotation
messages: Membrane

55661:CPB1
gene id: 55661:CPB1
uniprot id: A0A091GE76
names: Similarity
messages: Belongs to the peptidase M14 family.

55661:ITM2B
gene id: 55661:ITM2B
uniprot id: A0A091G232
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

55661:EEF1B2
gene id: 55661:EEF1B2
uniprot id: A0A091G2L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

55661:MAB21L2
gene id: 55661:MAB21L2
uniprot id: A0A091G1T6
names: Similarity
messages: Belongs to the mab-21 family.

55661:TPH1
gene id: 55661:TPH1
uniprot id: A0A091FN07
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

55661:RTF2
gene id: 55661:RTF2
uniprot id: A0A091FVI8
names: Similarity
messages: Belongs to the rtf2 family.

55661:CENPN
gene id: 55661:CENPN
uniprot id: A0A091GQ60
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

55661:LOC104067255
gene id: 55661:LOC104067255
uniprot id: A0A091H9D6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

55661:SEMA6A
gene id: 55661:SEMA6A
uniprot id: A0A091G6V5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

55661:FTCD
gene id: 55661:FTCD
uniprot id: A0A091H2Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds and promotes bundling of vimentin filaments originating from the Golgi.
messages: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
messages: Golgi apparatus
messages: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
messages: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
messages: In the N-terminal section; belongs to the formiminotransferase family.
messages: centriole

55661:NEUROD6
gene id: 55661:NEUROD6
uniprot id: A0A091GHE6
names: Subcellular Location Annotation
messages: Nucleus

55661:SLC39A9
gene id: 55661:SLC39A9
uniprot id: A0A091FKV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

55661:SLC26A9
gene id: 55661:SLC26A9
uniprot id: A0A091G7P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Ion transporter that can act both as an ion channel and anion exchanger. Mainly acts as a chloride channel, which mediate uncoupled chloride anion transport in an alternate-access mechanism where a saturable binding site is alternately exposed to either one or the other side of the membrane. Also acts as a DIDS- and thiosulfate- sensitive anion exchanger the exchange of chloride for bicarbonate ions across the cell membrane.
messages: Membrane

55661:MOS
gene id: 55661:MOS
uniprot id: A0A091FML3
names: Similarity
messages: Belongs to the protein kinase superfamily.

55661:MAT1A
gene id: 55661:MAT1A
uniprot id: A0A091GAH2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

55661:AMD1
gene id: 55661:AMD1
uniprot id: A0A091GY92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

55661:BARX2
gene id: 55661:BARX2
uniprot id: A0A091GIU5
names: Subcellular Location Annotation
messages: Nucleus

55661:CD9
gene id: 55661:CD9
uniprot id: A0A091GM00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

55661:EPHB6
gene id: 55661:EPHB6
uniprot id: A0A091GGG8
names: Subcellular Location Annotation
messages: Membrane

55661:TMEM230
gene id: 55661:TMEM230
uniprot id: A0A091FIT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

55661:MED27
gene id: 55661:MED27
uniprot id: A0A091GMD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 27 family.
messages: Nucleus

55661:MAS1
gene id: 55661:MAS1
uniprot id: A0A091GI78
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

55661:GABRA4
gene id: 55661:GABRA4
uniprot id: A0A091FZ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

55661:MAT2B
gene id: 55661:MAT2B
uniprot id: A0A091GA58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

55661:SULT1C4
gene id: 55661:SULT1C4
uniprot id: A0A091FXQ6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

55661:CAV3
gene id: 55661:CAV3
uniprot id: A0A091GD03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

55661:TYMS
gene id: 55661:TYMS
uniprot id: A0A091GBK7
names: Similarity
messages: Belongs to the thymidylate synthase family.

55661:MYF6
gene id: 55661:MYF6
uniprot id: A0A091G8W9
names: Subcellular Location Annotation
messages: Nucleus

55661:SGCG
gene id: 55661:SGCG
uniprot id: A0A091GGP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

55661:TMEM35A
gene id: 55661:TMEM35A
uniprot id: A0A091GCR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

55661:LOC104064097
gene id: 55661:LOC104064097
uniprot id: A0A091GFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

55661:LOC104066672
gene id: 55661:LOC104066672
uniprot id: A0A091FJ37
names: Similarity
messages: Belongs to the serpin family.

55661:MYADML2
gene id: 55661:MYADML2
uniprot id: A0A091FW00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

55661:NAT10
gene id: 55661:NAT10
uniprot id: A0A091FI08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

55661:CDC20
gene id: 55661:CDC20
uniprot id: A0A091FYF8
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

55661:WNT7A
gene id: 55661:WNT7A
uniprot id: A0A091GE75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

55661:GJA5
gene id: 55661:GJA5
uniprot id: A0A091FSH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

55661:FAM110B
gene id: 55661:FAM110B
uniprot id: A0A091G6D9
names: Similarity
messages: Belongs to the FAM110 family.

55661:ANKH
gene id: 55661:ANKH
uniprot id: A0A091FM73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

55661:LOC104057226
gene id: 55661:LOC104057226
uniprot id: A0A091FV88
names: Similarity
messages: Belongs to the CD225/Dispanin family.

55661:NKIRAS1
gene id: 55661:NKIRAS1
uniprot id: A0A091FP41
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

55661:CKMT2
gene id: 55661:CKMT2
uniprot id: A0A091G3K1
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

55661:GLUL
gene id: 55661:GLUL
uniprot id: A0A091G1C5
names: Similarity
messages: Belongs to the glutamine synthetase family.

55661:ATOH7
gene id: 55661:ATOH7
uniprot id: A0A091GHT1
names: Subcellular Location Annotation
messages: Nucleus
messages: Perikaryon
messages: axon

55661:MMP2
gene id: 55661:MMP2
uniprot id: A0A091FU85
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

55661:AK5
gene id: 55661:AK5
uniprot id: A0A091FYF0
names: Similarity
messages: Belongs to the adenylate kinase family.

55661:LOC104067415
gene id: 55661:LOC104067415
uniprot id: A0A091G8T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

55661:NUDC
gene id: 55661:NUDC
uniprot id: A0A091GHR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

55661:OVOL2
gene id: 55661:OVOL2
uniprot id: A0A091G4V1
names: Subcellular Location Annotation
messages: Nucleus

55661:SSRP1
gene id: 55661:SSRP1
uniprot id: A0A091G976
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

55661:SENP8
gene id: 55661:SENP8
uniprot id: A0A091GGM7
names: Similarity
messages: Belongs to the peptidase C48 family.

55661:TAGLN3
gene id: 55661:TAGLN3
uniprot id: A0A091GH12
names: Similarity
messages: Belongs to the calponin family.

55661:RPS3A
gene id: 55661:RPS3A
uniprot id: A0A091FLB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).
messages: Cytoplasm
messages: nucleolus

55661:AHSA1
gene id: 55661:AHSA1
uniprot id: A0A091GEY6
names: Similarity
messages: Belongs to the AHA1 family.

55661:CLDN11
gene id: 55661:CLDN11
uniprot id: A0A091FI71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

55661:TALDO1
gene id: 55661:TALDO1
uniprot id: A0A091GGN1
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

55661:LOC104068094
gene id: 55661:LOC104068094
uniprot id: A0A091FNL0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

55661:LOC104068682
gene id: 55661:LOC104068682
uniprot id: A0A091FMD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

55661:SLC41A2
gene id: 55661:SLC41A2
uniprot id: A0A091G6K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

55661:CCNK
gene id: 55661:CCNK
uniprot id: A0A091GLB7
names: Similarity
messages: Belongs to the cyclin family.

55661:CACNG2
gene id: 55661:CACNG2
uniprot id: A0A091H5W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

55661:CRYAA
gene id: 55661:CRYAA
uniprot id: A0A091G0Y2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

55661:TNFAIP6
gene id: 55661:TNFAIP6
uniprot id: A0A091FSW4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

55661:CRMP1
gene id: 55661:CRMP1
uniprot id: A0A091GAG7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

55661:TMEM30A
gene id: 55661:TMEM30A
uniprot id: A0A091GCY4
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

55661:NDUFS8
gene id: 55661:NDUFS8
uniprot id: A0A091H2F9
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

55661:KCNK5
gene id: 55661:KCNK5
uniprot id: A0A091G8I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

55661:JUN
gene id: 55661:JUN
uniprot id: A0A091GJT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

55661:LYN
gene id: 55661:LYN
uniprot id: A0A091FK40
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

55661:EMP1
gene id: 55661:EMP1
uniprot id: A0A091FVJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

55661:SPDYA
gene id: 55661:SPDYA
uniprot id: A0A091G4X0
names: Similarity
messages: Belongs to the Speedy/Ringo family.

55661:PPP1R1C
gene id: 55661:PPP1R1C
uniprot id: A0A091GDU4
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

55661:TSPAN5
gene id: 55661:TSPAN5
uniprot id: A0A091FUM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

55661:TMEM47
gene id: 55661:TMEM47
uniprot id: A0A091FJH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

55661:HOXA11
gene id: 55661:HOXA11
uniprot id: A0A091G0R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

55661:GRIA4
gene id: 55661:GRIA4
uniprot id: A0A091GQD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

55661:S100Z
gene id: 55661:S100Z
uniprot id: A0A091FVS1
names: Similarity
messages: Belongs to the S-100 family.

55661:ANXA1
gene id: 55661:ANXA1
uniprot id: A0A091G7J8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasm
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium

55661:LOC104058755
gene id: 55661:LOC104058755
uniprot id: A0A091FH35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

55661:ZNF706
gene id: 55661:ZNF706
uniprot id: A0A091FU19
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

55661:RIC8A
gene id: 55661:RIC8A
uniprot id: A0A091FXR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

55661:CALHM2
gene id: 55661:CALHM2
uniprot id: A0A091FK43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

55661:ARL6IP5
gene id: 55661:ARL6IP5
uniprot id: A0A091G938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

55661:TFAP2D
gene id: 55661:TFAP2D
uniprot id: A0A091FPE9
names: Similarity
messages: Belongs to the AP-2 family.

55661:IL7R
gene id: 55661:IL7R
uniprot id: A0A091GC95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Membrane

55661:FGF1
gene id: 55661:FGF1
uniprot id: A0A091FK63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

55661:HOXB9
gene id: 55661:HOXB9
uniprot id: A0A091FP05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

55661:CRYBB1
gene id: 55661:CRYBB1
uniprot id: A0A091G1X1
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

55661:MAGOH
gene id: 55661:MAGOH
uniprot id: A0A091G320
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

55661:CDKN1B
gene id: 55661:CDKN1B
uniprot id: A0A091H7T4
names: Similarity
messages: Belongs to the CDI family.

55661:SEMA6D
gene id: 55661:SEMA6D
uniprot id: A0A091GGH7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

55661:F2
gene id: 55661:F2
uniprot id: A0A091GNY2
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

55661:SS18L2
gene id: 55661:SS18L2
uniprot id: A0A091GJ54
names: Similarity
messages: Belongs to the SS18 family.

55661:USP35
gene id: 55661:USP35
uniprot id: A0A091GGN7
names: Similarity
messages: Belongs to the peptidase C19 family.

55661:MC4R
gene id: 55661:MC4R
uniprot id: A0A091FN23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

55661:SYNGR3
gene id: 55661:SYNGR3
uniprot id: A0A091GSK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

55661:AQP1
gene id: 55661:AQP1
uniprot id: A0A091FX60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

55661:VPS26B
gene id: 55661:VPS26B
uniprot id: A0A091GIV3
names: Similarity
messages: Belongs to the VPS26 family.

55661:OTC
gene id: 55661:OTC
uniprot id: A0A091FGQ7
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

55661:RHO
gene id: 55661:RHO
uniprot id: A0A091GD08
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

55661:KIFBP
gene id: 55661:KIFBP
uniprot id: A0A091GAL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

55661:WNT7B
gene id: 55661:WNT7B
uniprot id: A0A091GB14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

55661:CYGB
gene id: 55661:CYGB
uniprot id: A0A091GBV6
names: Similarity
messages: Belongs to the globin family.

55661:LOC104065331
gene id: 55661:LOC104065331
uniprot id: A0A091GFV5
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

55661:HOXA6
gene id: 55661:HOXA6
uniprot id: A0A091G401
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

55661:GPN3
gene id: 55661:GPN3
uniprot id: A0A091GC82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

55661:WSCD1
gene id: 55661:WSCD1
uniprot id: A0A091FVF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Golgi apparatus membrane
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

55661:APOD
gene id: 55661:APOD
uniprot id: A0A091GCF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

55661:LHFPL2
gene id: 55661:LHFPL2
uniprot id: A0A091GG32
names: Subcellular Location Annotation
messages: Membrane

55661:BDKRB2
gene id: 55661:BDKRB2
uniprot id: A0A091G0P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

55661:LOC104063758
gene id: 55661:LOC104063758
uniprot id: A0A091GF16
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

55661:EXOC7
gene id: 55661:EXOC7
uniprot id: A0A091GAW8
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

55661:LOC104066913
gene id: 55661:LOC104066913
uniprot id: A0A091FI95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

55661:LOC104067546
gene id: 55661:LOC104067546
uniprot id: A0A091FNM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

55661:LOC104067090
gene id: 55661:LOC104067090
uniprot id: A0A091GJZ2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

55661:SCN3B
gene id: 55661:SCN3B
uniprot id: A0A091FT20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

55661:EPHA7
gene id: 55661:EPHA7
uniprot id: A0A091FKZ5
names: Subcellular Location Annotation
messages: Membrane

55661:MALL
gene id: 55661:MALL
uniprot id: A0A091G4U8
names: Subcellular Location Annotation
messages: Membrane

55661:YIPF1
gene id: 55661:YIPF1
uniprot id: A0A091G3V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

55661:GAB3
gene id: 55661:GAB3
uniprot id: A0A091G7C1
names: Similarity
messages: Belongs to the GAB family.

55661:COG2
gene id: 55661:COG2
uniprot id: A0A091GED9
names: Similarity
messages: Belongs to the COG2 family.

55661:CDC34
gene id: 55661:CDC34
uniprot id: A0A091FPI9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

55661:RBM47
gene id: 55661:RBM47
uniprot id: A0A091GEI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Cytoplasm
messages: Nucleus

55661:CPLX4
gene id: 55661:CPLX4
uniprot id: A0A091G9F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

55661:MEOX2
gene id: 55661:MEOX2
uniprot id: A0A091FPK9
names: Subcellular Location Annotation
messages: Nucleus

55661:NSUN6
gene id: 55661:NSUN6
uniprot id: A0A091G128
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

55661:LOC104059960
gene id: 55661:LOC104059960
uniprot id: A0A091GRM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

55661:MET
gene id: 55661:MET
uniprot id: A0A091GDH7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

55661:SLC25A27
gene id: 55661:SLC25A27
uniprot id: A0A091FYW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

55661:GPR6
gene id: 55661:GPR6
uniprot id: A0A091GYA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

55661:TADA2A
gene id: 55661:TADA2A
uniprot id: A0A091H3R2
names: Subcellular Location Annotation
messages: Nucleus

55661:TIMM10
gene id: 55661:TIMM10
uniprot id: A0A091G810
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

55661:TJP2
gene id: 55661:TJP2
uniprot id: A0A091GE62
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

55661:BMP5
gene id: 55661:BMP5
uniprot id: A0A091GJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

55661:FERMT2
gene id: 55661:FERMT2
uniprot id: A0A091FZI0
names: Similarity
messages: Belongs to the kindlin family.

55661:NKX2-5
gene id: 55661:NKX2-5
uniprot id: A0A091GHI2
names: Subcellular Location Annotation
messages: Nucleus

55661:LOC104066411
gene id: 55661:LOC104066411
uniprot id: A0A091GIE2
names: Similarity
messages: Belongs to the globin family.

55661:ARSI
gene id: 55661:ARSI
uniprot id: A0A091FLY9
names: Similarity
messages: Belongs to the sulfatase family.

55661:DPH3
gene id: 55661:DPH3
uniprot id: A0A091GPN8
names: Similarity
messages: Belongs to the DPH3 family.

55661:RPL6
gene id: 55661:RPL6
uniprot id: A0A091G1U5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

55661:MRAP2
gene id: 55661:MRAP2
uniprot id: A0A091GCH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

55661:ATP6V0D1
gene id: 55661:ATP6V0D1
uniprot id: A0A091FP60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

55661:PTP4A1
gene id: 55661:PTP4A1
uniprot id: A0A091FMP4
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

55661:ADD3
gene id: 55661:ADD3
uniprot id: A0A091FKQ6
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

55661:PIGO
gene id: 55661:PIGO
uniprot id: A0A091FXK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

55661:XKR9
gene id: 55661:XKR9
uniprot id: A0A091FPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

55661:LOC104067122
gene id: 55661:LOC104067122
uniprot id: A0A091H904
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

55661:TNFRSF11B
gene id: 55661:TNFRSF11B
uniprot id: A0A091GJ09
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

55661:TPM4
gene id: 55661:TPM4
uniprot id: A0A091G8T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

55661:CALHM5
gene id: 55661:CALHM5
uniprot id: A0A091G753
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

55661:GDF5
gene id: 55661:GDF5
uniprot id: A0A091GDR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

55661:LOC104055778
gene id: 55661:LOC104055778
uniprot id: A0A091FVN4
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

55661:LOC104057265
gene id: 55661:LOC104057265
uniprot id: A0A091FXS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

55661:HOXD4
gene id: 55661:HOXD4
uniprot id: A0A091GDP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

55661:DIABLO
gene id: 55661:DIABLO
uniprot id: A0A091G046
names: Subcellular Location Annotation
messages: Mitochondrion

55661:GNG2
gene id: 55661:GNG2
uniprot id: A0A091G022
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

55661:NDST1
gene id: 55661:NDST1
uniprot id: A0A091FHA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

55661:MSTN
gene id: 55661:MSTN
uniprot id: A0A091GMQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

55661:LOC104055104
gene id: 55661:LOC104055104
uniprot id: A0A091FU68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Cytoplasm

55661:CLDN18
gene id: 55661:CLDN18
uniprot id: A0A091FJD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

55661:INS
gene id: 55661:INS
uniprot id: A0A091FRU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

55661:GABRB2
gene id: 55661:GABRB2
uniprot id: A0A091GA53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

55661:LOC104059959
gene id: 55661:LOC104059959
uniprot id: A0A091G609
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

55661:GNPNAT1
gene id: 55661:GNPNAT1
uniprot id: A0A091FY86
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

55661:LOC104061436
gene id: 55661:LOC104061436
uniprot id: A0A091GV45
names: Similarity
messages: Belongs to the peptidase M14 family.

55661:CRHR2
gene id: 55661:CRHR2
uniprot id: A0A091FX64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

55661:IAPP
gene id: 55661:IAPP
uniprot id: A0A091GJH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcitonin family.
messages: Secreted

55661:SLC24A1
gene id: 55661:SLC24A1
uniprot id: A0A091GIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

55661:FUCA1
gene id: 55661:FUCA1
uniprot id: A0A091GRY0
names: Function
names: Similarity
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.

55661:SLC5A7
gene id: 55661:SLC5A7
uniprot id: A0A091FTV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

55661:PPARGC1A
gene id: 55661:PPARGC1A
uniprot id: A0A091GAY6
names: Subcellular Location Annotation
messages: PML body

55661:TMEM45A
gene id: 55661:TMEM45A
uniprot id: A0A091FW17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

55661:RBM15B
gene id: 55661:RBM15B
uniprot id: A0A091GPE6
names: Similarity
messages: Belongs to the RRM Spen family.

55661:MED24
gene id: 55661:MED24
uniprot id: A0A091FFJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

55661:ACSL5
gene id: 55661:ACSL5
uniprot id: A0A091FMT8
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

55661:VPS18
gene id: 55661:VPS18
uniprot id: A0A091H9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

55661:BRS3
gene id: 55661:BRS3
uniprot id: A0A091G4S8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

55661:LOC104059369
gene id: 55661:LOC104059369
uniprot id: A0A091FLX7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

55661:PCMTD2
gene id: 55661:PCMTD2
uniprot id: A0A091G6F0
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

55661:HIGD1A
gene id: 55661:HIGD1A
uniprot id: A0A091GJ89
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

55661:TPRKB
gene id: 55661:TPRKB
uniprot id: A0A091FSL3
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

55661:PTH
gene id: 55661:PTH
uniprot id: A0A091GAJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.
messages: Secreted

55661:AQP3
gene id: 55661:AQP3
uniprot id: A0A091GGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

55661:GEM
gene id: 55661:GEM
uniprot id: A0A091FXZ5
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

55661:CNRIP1
gene id: 55661:CNRIP1
uniprot id: A0A091FVE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

55661:PDE6B
gene id: 55661:PDE6B
uniprot id: A0A091GCU6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

55661:EMX2
gene id: 55661:EMX2
uniprot id: A0A091G9R4
names: Subcellular Location Annotation
messages: Nucleus

55661:LOC104065332
gene id: 55661:LOC104065332
uniprot id: A0A091H4Q2
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

55661:CDH19
gene id: 55661:CDH19
uniprot id: A0A091FSL4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

55661:SQLE
gene id: 55661:SQLE
uniprot id: A0A091G309
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

55661:KDELR3
gene id: 55661:KDELR3
uniprot id: A0A091GKL0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

55661:ATP23
gene id: 55661:ATP23
uniprot id: A0A091GH40
names: Similarity
messages: Belongs to the peptidase M76 family.

55661:alpha-D
gene id: 55661:alpha-D
uniprot id: Q7ZT86
names: Similarity
messages: Belongs to the globin family.

55661:FUCA2
gene id: 55661:FUCA2
uniprot id: A0A091FLG4
names: Function
names: Similarity
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.

55661:SNX14
gene id: 55661:SNX14
uniprot id: A0A091G9K4
names: Similarity
messages: Belongs to the sorting nexin family.

55661:ATP5F1E
gene id: 55661:ATP5F1E
uniprot id: A0A091FJQ8
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

55661:LOC104060175
gene id: 55661:LOC104060175
uniprot id: A0A091G6J4
names: Similarity
messages: Belongs to the folate receptor family.

55661:ELOVL5
gene id: 55661:ELOVL5
uniprot id: A0A091GIU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: dendrite

55661:CLDN14
gene id: 55661:CLDN14
uniprot id: A0A091GEH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

55661:PCK1
gene id: 55661:PCK1
uniprot id: A0A091FI99
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

55661:CRYBA4
gene id: 55661:CRYBA4
uniprot id: A0A091G463
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

55661:VEPH1
gene id: 55661:VEPH1
uniprot id: A0A091FY99
names: Similarity
messages: Belongs to the MELT/VEPH family.

55661:KLHL15
gene id: 55661:KLHL15
uniprot id: A0A091GQA0
names: Subcellular Location Annotation
messages: Nucleus

55661:RBM22
gene id: 55661:RBM22
uniprot id: A0A091G6Z1
names: Similarity
messages: Belongs to the SLT11 family.

55661:CCND1
gene id: 55661:CCND1
uniprot id: A0A091FHZ1
names: Similarity
messages: Belongs to the cyclin family.

55661:SLC13A4
gene id: 55661:SLC13A4
uniprot id: A0A091GP96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

55661:TAT
gene id: 55661:TAT
uniprot id: A0A091G9N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

55661:LOC104055596
gene id: 55661:LOC104055596
uniprot id: A0A091FRI1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

55661:GYS2
gene id: 55661:GYS2
uniprot id: A0A091FNL4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

55661:NMUR2
gene id: 55661:NMUR2
uniprot id: A0A091FLD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

55661:FEN1
gene id: 55661:FEN1
uniprot id: A0A091GDP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Mitochondrion
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

55661:SNF8
gene id: 55661:SNF8
uniprot id: A0A091FQV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

55661:DYM
gene id: 55661:DYM
uniprot id: A0A091GEM7
names: Similarity
messages: Belongs to the dymeclin family.

55661:ACTA2
gene id: 55661:ACTA2
uniprot id: A0A091FP98
names: Similarity
messages: Belongs to the actin family.

55661:FAM135B
gene id: 55661:FAM135B
uniprot id: A0A091GCF7
names: Similarity
messages: Belongs to the FAM135 family.

55661:RHCE
gene id: 55661:RHCE
uniprot id: A0A091G7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

55661:DUS4L
gene id: 55661:DUS4L
uniprot id: A0A091FSM8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

55661:GNAL
gene id: 55661:GNAL
uniprot id: A0A091GGA6
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

55661:PSMB1
gene id: 55661:PSMB1
uniprot id: A0A091GHC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

55661:AARS2
gene id: 55661:AARS2
uniprot id: A0A091FJP6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

55661:DLX1
gene id: 55661:DLX1
uniprot id: A0A091FSW0
names: Subcellular Location Annotation
messages: Nucleus

55661:IL12B
gene id: 55661:IL12B
uniprot id: A0A091GD15
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

55661:QRFP
gene id: 55661:QRFP
uniprot id: A0A091GJB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFamide neuropeptide family.
messages: Secreted

55661:NSG2
gene id: 55661:NSG2
uniprot id: A0A091GHI6
names: Similarity
messages: Belongs to the NSG family.

55661:PTPN4
gene id: 55661:PTPN4
uniprot id: A0A091G9L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

55661:LOC104055955
gene id: 55661:LOC104055955
uniprot id: A0A091FGA7
names: Similarity
messages: Belongs to the globin family.

55661:PYGB
gene id: 55661:PYGB
uniprot id: A0A091GTE7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

55661:LOC104057257
gene id: 55661:LOC104057257
uniprot id: A0A091FZ48
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

55661:GPX7
gene id: 55661:GPX7
uniprot id: A0A091G4S0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

55661:CRYAB
gene id: 55661:CRYAB
uniprot id: A0A091GNL6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

55661:CACNG1
gene id: 55661:CACNG1
uniprot id: A0A091GB72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

55661:HTR2A
gene id: 55661:HTR2A
uniprot id: A0A091GI95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

55661:SLC41A3
gene id: 55661:SLC41A3
uniprot id: A0A091FJT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

55661:GDF9
gene id: 55661:GDF9
uniprot id: A0A091FK85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

55661:CA7
gene id: 55661:CA7
uniprot id: A0A091GG48
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

55661:PHGDH
gene id: 55661:PHGDH
uniprot id: A0A091GZN1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

55661:GAB1
gene id: 55661:GAB1
uniprot id: A0A091FJK1
names: Similarity
messages: Belongs to the GAB family.

55661:BOK
gene id: 55661:BOK
uniprot id: A0A091GIN5
names: Similarity
messages: Belongs to the Bcl-2 family.

55661:DMBX1
gene id: 55661:DMBX1
uniprot id: A0A091G709
names: Subcellular Location Annotation
messages: Nucleus

55661:NDUFB6
gene id: 55661:NDUFB6
uniprot id: A0A091FQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

55661:TRADD
gene id: 55661:TRADD
uniprot id: A0A091FSA8
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

55661:EXOSC2
gene id: 55661:EXOSC2
uniprot id: A0A091GKF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

55661:HSPB1
gene id: 55661:HSPB1
uniprot id: A0A091FZI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

55661:SPARC
gene id: 55661:SPARC
uniprot id: A0A091FHB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

55661:MAPK8
gene id: 55661:MAPK8
uniprot id: A0A091FPX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

55661:KCNJ2
gene id: 55661:KCNJ2
uniprot id: A0A091FUG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

55661:GPHB5
gene id: 55661:GPHB5
uniprot id: A0A091GC96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

55661:TARDBP
gene id: 55661:TARDBP
uniprot id: A0A091GT35
names: Subcellular Location Annotation
messages: Nucleus

55661:SNX20
gene id: 55661:SNX20
uniprot id: A0A091FR36
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

55661:ANXA8L1
gene id: 55661:ANXA8L1
uniprot id: A0A091FPY8
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

55661:TMEM170B
gene id: 55661:TMEM170B
uniprot id: A0A091G9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

55661:SPTSSA
gene id: 55661:SPTSSA
uniprot id: A0A091GVP6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

55661:HSPA2
gene id: 55661:HSPA2
uniprot id: A0A091GA19
names: Similarity
messages: Belongs to the heat shock protein 70 family.

55661:TGFB2
gene id: 55661:TGFB2
uniprot id: A0A091GHM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

55661:FABP7
gene id: 55661:FABP7
uniprot id: A0A091FWM5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

55661:DDO
gene id: 55661:DDO
uniprot id: A0A091GAV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

55661:EMC8
gene id: 55661:EMC8
uniprot id: A0A091G991
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

55661:NIP7
gene id: 55661:NIP7
uniprot id: A0A091FSJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

55661:SEH1L
gene id: 55661:SEH1L
uniprot id: A0A091GHH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

55661:GDNF
gene id: 55661:GDNF
uniprot id: A0A091G5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

55661:ADORA2B
gene id: 55661:ADORA2B
uniprot id: A0A091FYY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

55661:STAC
gene id: 55661:STAC
uniprot id: A0A091FV43
names: Subcellular Location Annotation
messages: sarcolemma

55661:FAM199X
gene id: 55661:FAM199X
uniprot id: A0A091GCS0
names: Similarity
messages: Belongs to the FAM199 family.

55661:TIPIN
gene id: 55661:TIPIN
uniprot id: A0A091GIT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

55661:LOC104057273
gene id: 55661:LOC104057273
uniprot id: A0A091FXS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

55661:ADA2
gene id: 55661:ADA2
uniprot id: A0A091FWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

55661:VEGFD
gene id: 55661:VEGFD
uniprot id: A0A091GB91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

55661:ITPA
gene id: 55661:ITPA
uniprot id: A0A091GMT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Pyrophosphatase that hydrolyzes the non-canonical purine (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

55661:ST3GAL6
gene id: 55661:ST3GAL6
uniprot id: A0A091GGK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

55661:MAB21L1
gene id: 55661:MAB21L1
uniprot id: A0A091GHR2
names: Similarity
messages: Belongs to the mab-21 family.

55661:CDKL1
gene id: 55661:CDKL1
uniprot id: A0A091FVN6
names: Similarity
messages: Belongs to the protein kinase superfamily.

55661:ATP6V1F
gene id: 55661:ATP6V1F
uniprot id: A0A091G9X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

55661:MYMK
gene id: 55661:MYMK
uniprot id: A0A091GMU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

55661:NPY1R
gene id: 55661:NPY1R
uniprot id: A0A091GBL4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

55661:LOC104060074
gene id: 55661:LOC104060074
uniprot id: A0A091G6V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

55661:ENOPH1
gene id: 55661:ENOPH1
uniprot id: A0A091G6S1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

55661:TXNL4B
gene id: 55661:TXNL4B
uniprot id: A0A091FS22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

55661:POLR2D
gene id: 55661:POLR2D
uniprot id: A0A091H798
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

55661:PPP2CB
gene id: 55661:PPP2CB
uniprot id: A0A091GDJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

55661:NUMB
gene id: 55661:NUMB
uniprot id: A0A091G7F8
names: Function
messages: Plays a role in the process of neurogenesis.

55661:CRHBP
gene id: 55661:CRHBP
uniprot id: A0A091FX86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

55661:PRKACB
gene id: 55661:PRKACB
uniprot id: A0A091GF94
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

55661:GTF2H2
gene id: 55661:GTF2H2
uniprot id: A0A091G3D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

55661:SERINC1
gene id: 55661:SERINC1
uniprot id: A0A091FWK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

55661:ATP6V0A4
gene id: 55661:ATP6V0A4
uniprot id: A0A091G0B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

55661:RHCG
gene id: 55661:RHCG
uniprot id: A0A091G3R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

55661:FAM167A
gene id: 55661:FAM167A
uniprot id: A0A091G7X7
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

55661:PDZK1IP1
gene id: 55661:PDZK1IP1
uniprot id: A0A091GS43
names: Subcellular Location Annotation
messages: Membrane

55661:UBE2R2
gene id: 55661:UBE2R2
uniprot id: A0A091GGE9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

55661:AGPAT3
gene id: 55661:AGPAT3
uniprot id: A0A091G0Y5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

55661:TRAF5
gene id: 55661:TRAF5
uniprot id: A0A091GLW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

55661:NPSR1
gene id: 55661:NPSR1
uniprot id: A0A091GJH3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

55661:ORMDL1
gene id: 55661:ORMDL1
uniprot id: A0A091G2P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

55661:TAF9B
gene id: 55661:TAF9B
uniprot id: A0A091GCX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

55661:PARK7
gene id: 55661:PARK7
uniprot id: A0A091GT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

55661:HOXB6
gene id: 55661:HOXB6
uniprot id: A0A091FQU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

55661:MAPKAP1
gene id: 55661:MAPKAP1
uniprot id: A0A091GN12
names: Similarity
messages: Belongs to the SIN1 family.

55661:MIEF1
gene id: 55661:MIEF1
uniprot id: A0A091GFZ1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

55661:NUDT3
gene id: 55661:NUDT3
uniprot id: A0A091GG21
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

55661:OGN
gene id: 55661:OGN
uniprot id: A0A091FXP9
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

55661:LOC104055791
gene id: 55661:LOC104055791
uniprot id: A0A091GGQ2
names: Function
names: Similarity
messages: Belongs to the apovitellenin family.
messages: Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes.

55661:LOC104057269
gene id: 55661:LOC104057269
uniprot id: A0A091FZ60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

55661:SULT4A1
gene id: 55661:SULT4A1
uniprot id: A0A091G8S5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

55661:KLHL40
gene id: 55661:KLHL40
uniprot id: A0A091FUI8
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

55661:CAPN15
gene id: 55661:CAPN15
uniprot id: A0A091GAS6
names: Similarity
messages: Belongs to the peptidase C2 family.

55661:TRAPPC2L
gene id: 55661:TRAPPC2L
uniprot id: A0A091G973
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

55661:GJB1
gene id: 55661:GJB1
uniprot id: A0A091GCQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

55661:NDUFA6
gene id: 55661:NDUFA6
uniprot id: A0A091FR94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

55661:TLL1
gene id: 55661:TLL1
uniprot id: A0A091GDE0
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

55661:FUT7
gene id: 55661:FUT7
uniprot id: A0A091G4F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

55661:LOC104055963
gene id: 55661:LOC104055963
uniprot id: A0A091FL20
names: Similarity
messages: Belongs to the globin family.

55661:HSPA14
gene id: 55661:HSPA14
uniprot id: A0A091FNE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: cytosol

55661:POSTN
gene id: 55661:POSTN
uniprot id: A0A091GHS0
names: Subcellular Location Annotation
messages: extracellular matrix

55661:VPS54
gene id: 55661:VPS54
uniprot id: A0A091FTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS54 family.
messages: trans-Golgi network

55661:LOC104059153
gene id: 55661:LOC104059153
uniprot id: A0A091G4I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

55661:SKI
gene id: 55661:SKI
uniprot id: A0A091GR93
names: Similarity
messages: Belongs to the SKI family.

55661:POU1F1
gene id: 55661:POU1F1
uniprot id: A0A091FSH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

55661:ITGB6
gene id: 55661:ITGB6
uniprot id: A0A091GDE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

55661:PDE6G
gene id: 55661:PDE6G
uniprot id: A0A091GQG7
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

55661:LOC104067897
gene id: 55661:LOC104067897
uniprot id: A0A091GA17
names: Similarity
messages: Belongs to the cytochrome P450 family.

55661:RBP5
gene id: 55661:RBP5
uniprot id: A0A091GDK2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

55661:RAB38
gene id: 55661:RAB38
uniprot id: A0A091GFX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

55661:FGFBP2
gene id: 55661:FGFBP2
uniprot id: A0A091FJG6
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

55661:PRPF18
gene id: 55661:PRPF18
uniprot id: A0A091FMV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

55661:COPG1
gene id: 55661:COPG1
uniprot id: A0A091FFN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

55661:PRL
gene id: 55661:PRL
uniprot id: A0A091G8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

55661:DLX5
gene id: 55661:DLX5
uniprot id: A0A091GKI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

55661:LOC104062394
gene id: 55661:LOC104062394
uniprot id: A0A091G8Y8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

55661:CASQ2
gene id: 55661:CASQ2
uniprot id: A0A091GGT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

55661:INHBA
gene id: 55661:INHBA
uniprot id: A0A091H673
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

55661:KCNK9
gene id: 55661:KCNK9
uniprot id: A0A091GDM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: pH-dependent, voltage-insensitive, background potassium channel protein.

55661:TUBE1
gene id: 55661:TUBE1
uniprot id: A0A091GAT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: cytoskeleton

55661:EHF
gene id: 55661:EHF
uniprot id: A0A091FQM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

55661:PSPH
gene id: 55661:PSPH
uniprot id: A0A091GK59
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

55661:SLC6A6
gene id: 55661:SLC6A6
uniprot id: A0A091GFD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

55661:NUP93
gene id: 55661:NUP93
uniprot id: A0A091FSB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

55661:CER1
gene id: 55661:CER1
uniprot id: A0A091FUZ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

55661:GPX8
gene id: 55661:GPX8
uniprot id: A0A091FS30
names: Similarity
messages: Belongs to the glutathione peroxidase family.

55661:EHD3
gene id: 55661:EHD3
uniprot id: A0A091GJU2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

55661:RIOK2
gene id: 55661:RIOK2
uniprot id: A0A091G5Y6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

55661:KRT222
gene id: 55661:KRT222
uniprot id: A0A091FNT5
names: Similarity
messages: Belongs to the intermediate filament family.

55661:SIX1
gene id: 55661:SIX1
uniprot id: A0A091G8Q9
names: Subcellular Location Annotation
messages: Nucleus

55661:MTERF3
gene id: 55661:MTERF3
uniprot id: A0A091FXY5
names: Similarity
messages: Belongs to the mTERF family.

55661:RDM1
gene id: 55661:RDM1
uniprot id: A0A091GEW4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleolus

55661:GNAS
gene id: 55661:GNAS
uniprot id: A0A091FFH6
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

55661:CCNC
gene id: 55661:CCNC
uniprot id: A0A091GC04
names: Similarity
messages: Belongs to the cyclin family.

55661:CKS2
gene id: 55661:CKS2
uniprot id: A0A091H1L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

55661:DAO
gene id: 55661:DAO
uniprot id: A0A091G080
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

55661:PPM1G
gene id: 55661:PPM1G
uniprot id: A0A091GLK5
names: Similarity
messages: Belongs to the PP2C family.

55661:LDB2
gene id: 55661:LDB2
uniprot id: A0A091G8Y1
names: Similarity
messages: Belongs to the LDB family.

55661:HDAC3
gene id: 55661:HDAC3
uniprot id: A0A091FNC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

55661:EML6
gene id: 55661:EML6
uniprot id: A0A091G4C8
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

55661:HOXA7
gene id: 55661:HOXA7
uniprot id: A0A091GPL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

55661:PSMA7
gene id: 55661:PSMA7
uniprot id: A0A091G9J6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

55661:FGF9
gene id: 55661:FGF9
uniprot id: A0A091GFH2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

55661:IL2RG
gene id: 55661:IL2RG
uniprot id: A0A091FN82
names: Subcellular Location Annotation
messages: Membrane

55661:UBA3
gene id: 55661:UBA3
uniprot id: A0A091G651
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

55661:MRPL12
gene id: 55661:MRPL12
uniprot id: A0A091GKX4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

55661:HBA2
gene id: 55661:HBA2
uniprot id: Q7ZT87
names: Similarity
messages: Belongs to the globin family.

55661:IGF2BP3
gene id: 55661:IGF2BP3
uniprot id: A0A091FND9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Cytoplasm

55661:P2RX5
gene id: 55661:P2RX5
uniprot id: A0A091FZX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

55661:LOC104060065
gene id: 55661:LOC104060065
uniprot id: A0A091G6T9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

55661:ORAI2
gene id: 55661:ORAI2
uniprot id: A0A091GNE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

55661:HOPX
gene id: 55661:HOPX
uniprot id: A0A091FLC0
names: Subcellular Location Annotation
messages: Nucleus

55661:TMED2
gene id: 55661:TMED2
uniprot id: A0A091FLU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

55661:WASHC1
gene id: 55661:WASHC1
uniprot id: A0A091FX67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

55661:TXNL4A
gene id: 55661:TXNL4A
uniprot id: A0A091FRU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

55661:TUBB6
gene id: 55661:TUBB6
uniprot id: A0A091GGA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

55661:DRD1
gene id: 55661:DRD1
uniprot id: A0A091GGD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

55661:SOSTDC1
gene id: 55661:SOSTDC1
uniprot id: A0A091FQ55
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

55661:LOC104057240
gene id: 55661:LOC104057240
uniprot id: A0A091FGQ0
names: Subcellular Location Annotation
messages: Membrane

55661:MED30
gene id: 55661:MED30
uniprot id: A0A091GHV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

55661:ZNF622
gene id: 55661:ZNF622
uniprot id: A0A091FNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

55661:LOC104065100
gene id: 55661:LOC104065100
uniprot id: A0A091GIM9
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

55661:LOC104059906
gene id: 55661:LOC104059906
uniprot id: A0A091G450
names: Similarity
messages: Belongs to the FBPase class 1 family.

55661:CHST1
gene id: 55661:CHST1
uniprot id: A0A091GKG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

55661:SNRPE
gene id: 55661:SNRPE
uniprot id: A0A091G6Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

55661:PTGR2
gene id: 55661:PTGR2
uniprot id: A0A091FMG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

55661:GJA3
gene id: 55661:GJA3
uniprot id: A0A091FV75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction