545695:TREAZ RS00450
gene id: 545695:TREAZ_RS00450
uniprot id: F5Y8L3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

545695:TREAZ RS09005
gene id: 545695:TREAZ_RS09005
uniprot id: F5YCV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

545695:TREAZ RS02045
gene id: 545695:TREAZ_RS02045
uniprot id: F5YBA8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

545695:TREAZ RS15375
gene id: 545695:TREAZ_RS15375
uniprot id: F5YDP9
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

545695:TREAZ RS04050
gene id: 545695:TREAZ_RS04050
uniprot id: F5YEN9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

545695:TREAZ RS04635
gene id: 545695:TREAZ_RS04635
uniprot id: F5YFW1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

545695:TREAZ RS10455
gene id: 545695:TREAZ_RS10455
uniprot id: F5YFH5
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

545695:TREAZ RS02500
gene id: 545695:TREAZ_RS02500
uniprot id: F5YBZ7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

545695:TREAZ RS08085
gene id: 545695:TREAZ_RS08085
uniprot id: F5YB11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

545695:TREAZ RS10805
gene id: 545695:TREAZ_RS10805
uniprot id: F5YG56
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

545695:TREAZ RS04240
gene id: 545695:TREAZ_RS04240
uniprot id: F5YF77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS14565
gene id: 545695:TREAZ_RS14565
uniprot id: F5YCC5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

545695:TREAZ RS04515
gene id: 545695:TREAZ_RS04515
uniprot id: F5YFD2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS10980
gene id: 545695:TREAZ_RS10980
uniprot id: F5YG89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS13110
gene id: 545695:TREAZ_RS13110
uniprot id: F5Y9R7
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS14655
gene id: 545695:TREAZ_RS14655
uniprot id: F5YCE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

545695:TREAZ RS13630
gene id: 545695:TREAZ_RS13630
uniprot id: F5YAH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

545695:TREAZ RS17450
gene id: 545695:TREAZ_RS17450
uniprot id: F5Y6Y2
names: Subcellular Location Annotation
messages: Cell inner membrane

545695:TREAZ RS15535
gene id: 545695:TREAZ_RS15535
uniprot id: F5YDT2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

545695:TREAZ RS02525
gene id: 545695:TREAZ_RS02525
uniprot id: F5YC02
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

545695:TREAZ RS00040
gene id: 545695:TREAZ_RS00040
uniprot id: F5Y7H0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

545695:TREAZ RS01055
gene id: 545695:TREAZ_RS01055
uniprot id: F5Y9E3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

545695:TREAZ RS13705
gene id: 545695:TREAZ_RS13705
uniprot id: F5YAJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

545695:TREAZ RS01025
gene id: 545695:TREAZ_RS01025
uniprot id: F5Y9D7
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

545695:TREAZ RS03080
gene id: 545695:TREAZ_RS03080
uniprot id: F5YCS0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

545695:TREAZ RS06575
gene id: 545695:TREAZ_RS06575
uniprot id: F5Y8U7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

545695:TREAZ RS13310
gene id: 545695:TREAZ_RS13310
uniprot id: F5Y9W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

545695:TREAZ RS11950
gene id: 545695:TREAZ_RS11950
uniprot id: F5Y7R9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

545695:TREAZ RS05705
gene id: 545695:TREAZ_RS05705
uniprot id: F5Y771
names: Similarity
messages: Belongs to the FemABX family.

545695:TREAZ RS07525
gene id: 545695:TREAZ_RS07525
uniprot id: F5YA96
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

545695:TREAZ RS05545
gene id: 545695:TREAZ_RS05545
uniprot id: F5Y737
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

545695:TREAZ RS06700
gene id: 545695:TREAZ_RS06700
uniprot id: F5Y8X1
names: Subcellular Location Annotation
messages: Periplasmic flagellum

545695:TREAZ RS14050
gene id: 545695:TREAZ_RS14050
uniprot id: F5YB70
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

545695:TREAZ RS14815
gene id: 545695:TREAZ_RS14815
uniprot id: F5YCH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

545695:TREAZ RS00555
gene id: 545695:TREAZ_RS00555
uniprot id: F5Y8N5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS02880
gene id: 545695:TREAZ_RS02880
uniprot id: F5YCM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

545695:TREAZ RS04780
gene id: 545695:TREAZ_RS04780
uniprot id: F5YFZ2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

545695:TREAZ RS05210
gene id: 545695:TREAZ_RS05210
uniprot id: F5Y6P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

545695:TREAZ RS12095
gene id: 545695:TREAZ_RS12095
uniprot id: F5Y7V1
names: Similarity
messages: Belongs to the universal stress protein A family.

545695:TREAZ RS15655
gene id: 545695:TREAZ_RS15655
uniprot id: F5YDV4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

545695:TREAZ RS16585
gene id: 545695:TREAZ_RS16585
uniprot id: F5YFQ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

545695:TREAZ RS13895
gene id: 545695:TREAZ_RS13895
uniprot id: F5YB38
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

545695:TREAZ RS11710
gene id: 545695:TREAZ_RS11710
uniprot id: F5Y7D4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

545695:TREAZ RS04920
gene id: 545695:TREAZ_RS04920
uniprot id: F5YG17
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

545695:TREAZ RS06455
gene id: 545695:TREAZ_RS06455
uniprot id: F5Y8B8
names: Similarity
messages: Belongs to the UPF0237 family.

545695:TREAZ RS01550
gene id: 545695:TREAZ_RS01550
uniprot id: F5YA46
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS05145
gene id: 545695:TREAZ_RS05145
uniprot id: F5Y6N0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

545695:TREAZ RS01065
gene id: 545695:TREAZ_RS01065
uniprot id: F5Y9E5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

545695:TREAZ RS03540
gene id: 545695:TREAZ_RS03540
uniprot id: F5YDX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS09770
gene id: 545695:TREAZ_RS09770
uniprot id: F5YE81
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS10570
gene id: 545695:TREAZ_RS10570
uniprot id: F5YFJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

545695:TREAZ RS12855
gene id: 545695:TREAZ_RS12855
uniprot id: F5Y964
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

545695:TREAZ RS09425
gene id: 545695:TREAZ_RS09425
uniprot id: F5YDJ9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

545695:TREAZ RS11390
gene id: 545695:TREAZ_RS11390
uniprot id: F5Y6Z2
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS00410
gene id: 545695:TREAZ_RS00410
uniprot id: F5Y850
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

545695:TREAZ RS00970
gene id: 545695:TREAZ_RS00970
uniprot id: F5Y9C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

545695:TREAZ RS00355
gene id: 545695:TREAZ_RS00355
uniprot id: F5Y839
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

545695:TREAZ RS14720
gene id: 545695:TREAZ_RS14720
uniprot id: F5YCF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

545695:TREAZ RS14550
gene id: 545695:TREAZ_RS14550
uniprot id: F5YCC2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

545695:TREAZ RS14740
gene id: 545695:TREAZ_RS14740
uniprot id: F5YCG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

545695:TREAZ RS06370
gene id: 545695:TREAZ_RS06370
uniprot id: F5Y8A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS10575
gene id: 545695:TREAZ_RS10575
uniprot id: F5YFK0
names: Similarity
messages: Belongs to the DprA/Smf family.

545695:TREAZ RS06160
gene id: 545695:TREAZ_RS06160
uniprot id: F5Y859
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

545695:TREAZ RS03820
gene id: 545695:TREAZ_RS03820
uniprot id: F5YE32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

545695:TREAZ RS04560
gene id: 545695:TREAZ_RS04560
uniprot id: F5YFE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

545695:TREAZ RS11075
gene id: 545695:TREAZ_RS11075
uniprot id: F5YGA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

545695:TREAZ RS09075
gene id: 545695:TREAZ_RS09075
uniprot id: F5YCW9
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS03845
gene id: 545695:TREAZ_RS03845
uniprot id: F5YEJ7
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

545695:TREAZ RS02910
gene id: 545695:TREAZ_RS02910
uniprot id: F5YCN3
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

545695:TREAZ RS02385
gene id: 545695:TREAZ_RS02385
uniprot id: F5YBX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

545695:TREAZ RS00110
gene id: 545695:TREAZ_RS00110
uniprot id: F5Y7Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS11295
gene id: 545695:TREAZ_RS11295
uniprot id: F5Y6X4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

545695:TREAZ RS07600
gene id: 545695:TREAZ_RS07600
uniprot id: F5YAB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

545695:TREAZ RS03810
gene id: 545695:TREAZ_RS03810
uniprot id: F5YE30
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

545695:TREAZ RS13565
gene id: 545695:TREAZ_RS13565
uniprot id: F5YAG3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

545695:TREAZ RS07680
gene id: 545695:TREAZ_RS07680
uniprot id: F5YAC8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

545695:TREAZ RS10520
gene id: 545695:TREAZ_RS10520
uniprot id: F5YFI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS15275
gene id: 545695:TREAZ_RS15275
uniprot id: F5YD77
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

545695:TREAZ RS10335
gene id: 545695:TREAZ_RS10335
uniprot id: F5YEZ4
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

545695:TREAZ RS01490
gene id: 545695:TREAZ_RS01490
uniprot id: F5YA34
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

545695:TREAZ RS11695
gene id: 545695:TREAZ_RS11695
uniprot id: F5Y7D1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

545695:TREAZ RS03975
gene id: 545695:TREAZ_RS03975
uniprot id: F5YEM3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-100 inactivates the nitrogenase reductase and regulates nitrogenase activity.

545695:TREAZ RS11875
gene id: 545695:TREAZ_RS11875
uniprot id: F5Y7Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

545695:TREAZ RS04930
gene id: 545695:TREAZ_RS04930
uniprot id: F5YG19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

545695:TREAZ RS11800
gene id: 545695:TREAZ_RS11800
uniprot id: F5Y7F2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

545695:TREAZ RS10295
gene id: 545695:TREAZ_RS10295
uniprot id: F5YEY6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

545695:TREAZ RS14745
gene id: 545695:TREAZ_RS14745
uniprot id: F5YCG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

545695:TREAZ RS00535
gene id: 545695:TREAZ_RS00535
uniprot id: F5Y8N1
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS01495
gene id: 545695:TREAZ_RS01495
uniprot id: F5YA35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS12955
gene id: 545695:TREAZ_RS12955
uniprot id: F5Y985
names: Similarity
messages: Belongs to the HisA/HisF family.

545695:TREAZ RS01225
gene id: 545695:TREAZ_RS01225
uniprot id: F5Y9Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS07670
gene id: 545695:TREAZ_RS07670
uniprot id: F5YAC6
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS03030
gene id: 545695:TREAZ_RS03030
uniprot id: F5YCR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

545695:TREAZ RS13515
gene id: 545695:TREAZ_RS13515
uniprot id: F5YAF3
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

545695:TREAZ RS11975
gene id: 545695:TREAZ_RS11975
uniprot id: F5Y7S6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

545695:TREAZ RS13930
gene id: 545695:TREAZ_RS13930
uniprot id: F5YB45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

545695:TREAZ RS15725
gene id: 545695:TREAZ_RS15725
uniprot id: F5YEC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS15365
gene id: 545695:TREAZ_RS15365
uniprot id: F5YDP7
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

545695:TREAZ RS13010
gene id: 545695:TREAZ_RS13010
uniprot id: F5Y995
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

545695:TREAZ RS08560
gene id: 545695:TREAZ_RS08560
uniprot id: F5YC56
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

545695:TREAZ RS01895
gene id: 545695:TREAZ_RS01895
uniprot id: F5YAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

545695:TREAZ RS05240
gene id: 545695:TREAZ_RS05240
uniprot id: F5Y6P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

545695:TREAZ RS13375
gene id: 545695:TREAZ_RS13375
uniprot id: F5Y9X3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

545695:TREAZ RS06830
gene id: 545695:TREAZ_RS06830
uniprot id: F5Y8Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS07475
gene id: 545695:TREAZ_RS07475
uniprot id: F5YA85
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

545695:TREAZ RS02480
gene id: 545695:TREAZ_RS02480
uniprot id: F5YBZ3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

545695:TREAZ RS12840
gene id: 545695:TREAZ_RS12840
uniprot id: F5Y961
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS04955
gene id: 545695:TREAZ_RS04955
uniprot id: F5YG24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS13850
gene id: 545695:TREAZ_RS13850
uniprot id: F5YB28
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

545695:TREAZ RS12135
gene id: 545695:TREAZ_RS12135
uniprot id: F5Y7W0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

545695:TREAZ RS15185
gene id: 545695:TREAZ_RS15185
uniprot id: F5YD57
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

545695:TREAZ RS12985
gene id: 545695:TREAZ_RS12985
uniprot id: F5Y991
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

545695:TREAZ RS01075
gene id: 545695:TREAZ_RS01075
uniprot id: F5Y9E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS15550
gene id: 545695:TREAZ_RS15550
uniprot id: F5YDT4
names: Similarity
messages: Belongs to the CapA family.

545695:TREAZ RS05925
gene id: 545695:TREAZ_RS05925
uniprot id: F5Y7K1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

545695:TREAZ RS02865
gene id: 545695:TREAZ_RS02865
uniprot id: F5YCM4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

545695:TREAZ RS06305
gene id: 545695:TREAZ_RS06305
uniprot id: F5Y887
names: Similarity
messages: Belongs to the FGGY kinase family.

545695:TREAZ RS17455
gene id: 545695:TREAZ_RS17455
uniprot id: F5Y7C8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

545695:TREAZ RS12140
gene id: 545695:TREAZ_RS12140
uniprot id: F5Y7W1
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

545695:TREAZ RS06670
gene id: 545695:TREAZ_RS06670
uniprot id: F5Y8W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

545695:TREAZ RS13625
gene id: 545695:TREAZ_RS13625
uniprot id: F5YAH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS06555
gene id: 545695:TREAZ_RS06555
uniprot id: F5Y8U3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

545695:TREAZ RS14605
gene id: 545695:TREAZ_RS14605
uniprot id: F5YCD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS09375
gene id: 545695:TREAZ_RS09375
uniprot id: F5YDI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Periplasm
messages: Periplasmic flagellum
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.

545695:TREAZ RS10740
gene id: 545695:TREAZ_RS10740
uniprot id: F5YG43
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

545695:TREAZ RS13200
gene id: 545695:TREAZ_RS13200
uniprot id: F5Y9T7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS16955
gene id: 545695:TREAZ_RS16955
uniprot id: F5YGD6
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS00380
gene id: 545695:TREAZ_RS00380
uniprot id: F5Y844
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

545695:TREAZ RS01220
gene id: 545695:TREAZ_RS01220
uniprot id: F5Y9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS10160
gene id: 545695:TREAZ_RS10160
uniprot id: F5YEW1
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

545695:TREAZ RS15290
gene id: 545695:TREAZ_RS15290
uniprot id: F5YDN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

545695:TREAZ RS05825
gene id: 545695:TREAZ_RS05825
uniprot id: F5Y7I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

545695:TREAZ RS15565
gene id: 545695:TREAZ_RS15565
uniprot id: F5YDT7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

545695:TREAZ RS06275
gene id: 545695:TREAZ_RS06275
uniprot id: F5Y881
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

545695:TREAZ RS13095
gene id: 545695:TREAZ_RS13095
uniprot id: F5Y9R4
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

545695:TREAZ RS18025
gene id: 545695:TREAZ_RS18025
uniprot id: F5Y8W7
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS07990
gene id: 545695:TREAZ_RS07990
uniprot id: F5YAZ2
names: Subcellular Location Annotation
messages: Cytoplasm

545695:TREAZ RS00400
gene id: 545695:TREAZ_RS00400
uniprot id: F5Y848
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

545695:TREAZ RS04795
gene id: 545695:TREAZ_RS04795
uniprot id: F5YFZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

545695:TREAZ RS15410
gene id: 545695:TREAZ_RS15410
uniprot id: F5YDQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

545695:TREAZ RS06930
gene id: 545695:TREAZ_RS06930
uniprot id: F5Y918
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

545695:TREAZ RS07715
gene id: 545695:TREAZ_RS07715
uniprot id: F5YAT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

545695:TREAZ RS08035
gene id: 545695:TREAZ_RS08035
uniprot id: F5YB01
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

545695:TREAZ RS13100
gene id: 545695:TREAZ_RS13100
uniprot id: F5Y9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS08415
gene id: 545695:TREAZ_RS08415
uniprot id: F5YBN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

545695:TREAZ RS16965
gene id: 545695:TREAZ_RS16965
uniprot id: F5YGD8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

545695:TREAZ RS12280
gene id: 545695:TREAZ_RS12280
uniprot id: F5Y8E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

545695:TREAZ RS07840
gene id: 545695:TREAZ_RS07840
uniprot id: F5YAW1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

545695:TREAZ RS00600
gene id: 545695:TREAZ_RS00600
uniprot id: F5Y8P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

545695:TREAZ RS04380
gene id: 545695:TREAZ_RS04380
uniprot id: F5YFA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

545695:TREAZ RS14375
gene id: 545695:TREAZ_RS14375
uniprot id: F5YBT8
names: Similarity
messages: Belongs to the UbiD family.

545695:TREAZ RS14625
gene id: 545695:TREAZ_RS14625
uniprot id: F5YCD8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

545695:TREAZ RS14370
gene id: 545695:TREAZ_RS14370
uniprot id: F5YBT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

545695:TREAZ RS14570
gene id: 545695:TREAZ_RS14570
uniprot id: F5YCC6
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.

545695:TREAZ RS02435
gene id: 545695:TREAZ_RS02435
uniprot id: F5YBY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

545695:TREAZ RS10115
gene id: 545695:TREAZ_RS10115
uniprot id: F5YEV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

545695:TREAZ RS08920
gene id: 545695:TREAZ_RS08920
uniprot id: F5YCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS16205
gene id: 545695:TREAZ_RS16205
uniprot id: F5YF26
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

545695:TREAZ RS06170
gene id: 545695:TREAZ_RS06170
uniprot id: F5Y861
names: Similarity
messages: Belongs to the peptidase S33 family.

545695:TREAZ RS17265
gene id: 545695:TREAZ_RS17265
uniprot id: F5YDW8
names: Similarity
messages: Belongs to the peptidase C40 family.

545695:TREAZ RS15000
gene id: 545695:TREAZ_RS15000
uniprot id: F5YD21
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

545695:TREAZ RS11405
gene id: 545695:TREAZ_RS11405
uniprot id: F5Y6Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS11780
gene id: 545695:TREAZ_RS11780
uniprot id: F5Y7E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS03190
gene id: 545695:TREAZ_RS03190
uniprot id: F5YDA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS13905
gene id: 545695:TREAZ_RS13905
uniprot id: F5YB40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

545695:TREAZ RS00515
gene id: 545695:TREAZ_RS00515
uniprot id: F5Y8M7
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS06460
gene id: 545695:TREAZ_RS06460
uniprot id: F5Y8B9
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

545695:TREAZ RS07880
gene id: 545695:TREAZ_RS07880
uniprot id: F5YAW9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

545695:TREAZ RS13900
gene id: 545695:TREAZ_RS13900
uniprot id: F5YB39
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS06775
gene id: 545695:TREAZ_RS06775
uniprot id: F5Y8Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

545695:TREAZ RS02845
gene id: 545695:TREAZ_RS02845
uniprot id: F5YCM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

545695:TREAZ RS02570
gene id: 545695:TREAZ_RS02570
uniprot id: F5YC11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

545695:TREAZ RS11235
gene id: 545695:TREAZ_RS11235
uniprot id: F5Y6W2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

545695:TREAZ RS08515
gene id: 545695:TREAZ_RS08515
uniprot id: F5YC47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS02825
gene id: 545695:TREAZ_RS02825
uniprot id: F5YCL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

545695:TREAZ RS01685
gene id: 545695:TREAZ_RS01685
uniprot id: F5YAM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

545695:TREAZ RS10515
gene id: 545695:TREAZ_RS10515
uniprot id: F5YFI7
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS07690
gene id: 545695:TREAZ_RS07690
uniprot id: F5YAD0
names: Similarity
messages: Belongs to the YicC/YloC family.

545695:TREAZ RS03615
gene id: 545695:TREAZ_RS03615
uniprot id: F5YDZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

545695:TREAZ RS10035
gene id: 545695:TREAZ_RS10035
uniprot id: F5YET6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

545695:TREAZ RS11670
gene id: 545695:TREAZ_RS11670
uniprot id: F5Y7C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

545695:TREAZ RS10695
gene id: 545695:TREAZ_RS10695
uniprot id: F5YFM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

545695:TREAZ RS10305
gene id: 545695:TREAZ_RS10305
uniprot id: F5YEY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

545695:TREAZ RS00540
gene id: 545695:TREAZ_RS00540
uniprot id: F5Y8N2
names: Similarity
messages: Belongs to the hyi family.

545695:TREAZ RS16145
gene id: 545695:TREAZ_RS16145
uniprot id: F5YF13
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

545695:TREAZ RS11960
gene id: 545695:TREAZ_RS11960
uniprot id: F5Y7S1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

545695:TREAZ RS14235
gene id: 545695:TREAZ_RS14235
uniprot id: F5YBQ9
names: Similarity
messages: Belongs to the glutamine synthetase family.

545695:TREAZ RS07665
gene id: 545695:TREAZ_RS07665
uniprot id: F5YAC5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

545695:TREAZ RS12150
gene id: 545695:TREAZ_RS12150
uniprot id: F5Y7W3
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

545695:TREAZ RS10320
gene id: 545695:TREAZ_RS10320
uniprot id: F5YEZ1
names: Similarity
messages: Belongs to the class-I fumarase family.

545695:TREAZ RS13055
gene id: 545695:TREAZ_RS13055
uniprot id: F5Y9Q6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

545695:TREAZ RS00510
gene id: 545695:TREAZ_RS00510
uniprot id: F5Y8M6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

545695:TREAZ RS01385
gene id: 545695:TREAZ_RS01385
uniprot id: F5YA14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

545695:TREAZ RS07970
gene id: 545695:TREAZ_RS07970
uniprot id: F5YAY8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

545695:TREAZ RS17275
gene id: 545695:TREAZ_RS17275
uniprot id: F5YEP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

545695:TREAZ RS02870
gene id: 545695:TREAZ_RS02870
uniprot id: F5YCM5
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

545695:TREAZ RS10495
gene id: 545695:TREAZ_RS10495
uniprot id: F5YFI3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

545695:TREAZ RS13495
gene id: 545695:TREAZ_RS13495
uniprot id: F5YAE8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

545695:TREAZ RS09755
gene id: 545695:TREAZ_RS09755
uniprot id: F5YE78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

545695:TREAZ RS15855
gene id: 545695:TREAZ_RS15855
uniprot id: F5YEF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

545695:TREAZ RS14755
gene id: 545695:TREAZ_RS14755
uniprot id: F5YCG4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS05425
gene id: 545695:TREAZ_RS05425
uniprot id: F5Y712
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

545695:TREAZ RS15840
gene id: 545695:TREAZ_RS15840
uniprot id: F5YEE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

545695:TREAZ RS15540
gene id: 545695:TREAZ_RS15540
uniprot id: F5YDT3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

545695:TREAZ RS00050
gene id: 545695:TREAZ_RS00050
uniprot id: F5Y7H2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

545695:TREAZ RS01270
gene id: 545695:TREAZ_RS01270
uniprot id: F5Y9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS02330
gene id: 545695:TREAZ_RS02330
uniprot id: F5YBG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

545695:TREAZ RS05400
gene id: 545695:TREAZ_RS05400
uniprot id: F5Y6S9
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

545695:TREAZ RS16910
gene id: 545695:TREAZ_RS16910
uniprot id: F5YGC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

545695:TREAZ RS14280
gene id: 545695:TREAZ_RS14280
uniprot id: F5YBS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

545695:TREAZ RS07650
gene id: 545695:TREAZ_RS07650
uniprot id: F5YAC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

545695:TREAZ RS04820
gene id: 545695:TREAZ_RS04820
uniprot id: F5YFZ9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

545695:TREAZ RS05470
gene id: 545695:TREAZ_RS05470
uniprot id: F5Y721
names: Similarity
messages: Belongs to the NadC/ModD family.

545695:TREAZ RS09055
gene id: 545695:TREAZ_RS09055
uniprot id: F5YCW6
names: Similarity
messages: Belongs to the MEMO1 family.

545695:TREAZ RS14020
gene id: 545695:TREAZ_RS14020
uniprot id: F5YB64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS08015
gene id: 545695:TREAZ_RS08015
uniprot id: F5YAZ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

545695:TREAZ RS04290
gene id: 545695:TREAZ_RS04290
uniprot id: F5YF85
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

545695:TREAZ RS15020
gene id: 545695:TREAZ_RS15020
uniprot id: F5YD25
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS11690
gene id: 545695:TREAZ_RS11690
uniprot id: F5Y7D0
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

545695:TREAZ RS02805
gene id: 545695:TREAZ_RS02805
uniprot id: F5YCL2
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

545695:TREAZ RS16525
gene id: 545695:TREAZ_RS16525
uniprot id: F5YFP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

545695:TREAZ RS02615
gene id: 545695:TREAZ_RS02615
uniprot id: F5YC20
names: Similarity
messages: Belongs to the ribulokinase family.

545695:TREAZ RS10730
gene id: 545695:TREAZ_RS10730
uniprot id: F5YG42
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

545695:TREAZ RS10150
gene id: 545695:TREAZ_RS10150
uniprot id: F5YEV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

545695:TREAZ RS02530
gene id: 545695:TREAZ_RS02530
uniprot id: F5YC03
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

545695:TREAZ RS04760
gene id: 545695:TREAZ_RS04760
uniprot id: F5YFY8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

545695:TREAZ RS10450
gene id: 545695:TREAZ_RS10450
uniprot id: F5YFH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

545695:TREAZ RS02375
gene id: 545695:TREAZ_RS02375
uniprot id: F5YBX2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

545695:TREAZ RS06770
gene id: 545695:TREAZ_RS06770
uniprot id: F5Y8Y4
names: Similarity
messages: Belongs to the DprA/Smf family.

545695:TREAZ RS06225
gene id: 545695:TREAZ_RS06225
uniprot id: F5Y871
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS07410
gene id: 545695:TREAZ_RS07410
uniprot id: F5YA72
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

545695:TREAZ RS13915
gene id: 545695:TREAZ_RS13915
uniprot id: F5YB42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

545695:TREAZ RS15595
gene id: 545695:TREAZ_RS15595
uniprot id: F5YDU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

545695:TREAZ RS13925
gene id: 545695:TREAZ_RS13925
uniprot id: F5YB44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

545695:TREAZ RS05715
gene id: 545695:TREAZ_RS05715
uniprot id: F5Y773
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

545695:TREAZ RS08675
gene id: 545695:TREAZ_RS08675
uniprot id: F5YC82
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

545695:TREAZ RS01320
gene id: 545695:TREAZ_RS01320
uniprot id: F5YA01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

545695:TREAZ RS00315
gene id: 545695:TREAZ_RS00315
uniprot id: F5Y830
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

545695:TREAZ RS02325
gene id: 545695:TREAZ_RS02325
uniprot id: F5YBG3
names: Similarity
messages: Belongs to the DinB family.

545695:TREAZ RS00900
gene id: 545695:TREAZ_RS00900
uniprot id: F5Y9B2
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

545695:TREAZ RS07110
gene id: 545695:TREAZ_RS07110
uniprot id: F5Y9L0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

545695:TREAZ RS16830
gene id: 545695:TREAZ_RS16830
uniprot id: F5YFV6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

545695:TREAZ RS15325
gene id: 545695:TREAZ_RS15325
uniprot id: F5YDN9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

545695:TREAZ RS14220
gene id: 545695:TREAZ_RS14220
uniprot id: F5YBQ7
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS12295
gene id: 545695:TREAZ_RS12295
uniprot id: F5Y8E6
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

545695:TREAZ RS02905
gene id: 545695:TREAZ_RS02905
uniprot id: F5YCN2
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

545695:TREAZ RS05360
gene id: 545695:TREAZ_RS05360
uniprot id: F5Y6S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS02765
gene id: 545695:TREAZ_RS02765
uniprot id: F5YCK1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

545695:TREAZ RS14180
gene id: 545695:TREAZ_RS14180
uniprot id: F5YBP9
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS01040
gene id: 545695:TREAZ_RS01040
uniprot id: F5Y9E0
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

545695:TREAZ RS11775
gene id: 545695:TREAZ_RS11775
uniprot id: F5Y7E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS09185
gene id: 545695:TREAZ_RS09185
uniprot id: F5YCZ5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

545695:TREAZ RS15620
gene id: 545695:TREAZ_RS15620
uniprot id: F5YDU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

545695:TREAZ RS00610
gene id: 545695:TREAZ_RS00610
uniprot id: F5Y8P5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

545695:TREAZ RS04090
gene id: 545695:TREAZ_RS04090
uniprot id: F5YEP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

545695:TREAZ RS14400
gene id: 545695:TREAZ_RS14400
uniprot id: F5YBU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS15440
gene id: 545695:TREAZ_RS15440
uniprot id: F5YDR1
names: Similarity
messages: Belongs to the PspA/IM30 family.

545695:TREAZ RS03650
gene id: 545695:TREAZ_RS03650
uniprot id: F5YE00
names: Similarity
messages: Belongs to the DEAD box helicase family.

545695:TREAZ RS06050
gene id: 545695:TREAZ_RS06050
uniprot id: F5Y7N0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

545695:TREAZ RS04415
gene id: 545695:TREAZ_RS04415
uniprot id: F5YFB0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS07780
gene id: 545695:TREAZ_RS07780
uniprot id: F5YAU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

545695:TREAZ RS07100
gene id: 545695:TREAZ_RS07100
uniprot id: F5Y9K8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

545695:TREAZ RS02790
gene id: 545695:TREAZ_RS02790
uniprot id: F5YCK9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

545695:TREAZ RS05335
gene id: 545695:TREAZ_RS05335
uniprot id: F5Y6R7
names: Subcellular Location Annotation
messages: Periplasmic flagellum

545695:TREAZ RS06665
gene id: 545695:TREAZ_RS06665
uniprot id: F5Y8W4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

545695:TREAZ RS07005
gene id: 545695:TREAZ_RS07005
uniprot id: F5Y9J1
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

545695:TREAZ RS10645
gene id: 545695:TREAZ_RS10645
uniprot id: F5YFL8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS13390
gene id: 545695:TREAZ_RS13390
uniprot id: F5Y9X6
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

545695:TREAZ RS09690
gene id: 545695:TREAZ_RS09690
uniprot id: F5YE61
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

545695:TREAZ RS17095
gene id: 545695:TREAZ_RS17095
uniprot id: F5YGG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

545695:TREAZ RS00345
gene id: 545695:TREAZ_RS00345
uniprot id: F5Y836
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

545695:TREAZ RS12270
gene id: 545695:TREAZ_RS12270
uniprot id: F5Y8E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

545695:TREAZ RS02835
gene id: 545695:TREAZ_RS02835
uniprot id: F5YCL8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

545695:TREAZ RS04915
gene id: 545695:TREAZ_RS04915
uniprot id: F5YG16
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

545695:TREAZ RS02900
gene id: 545695:TREAZ_RS02900
uniprot id: F5YCN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS08865
gene id: 545695:TREAZ_RS08865
uniprot id: F5YCS9
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS10630
gene id: 545695:TREAZ_RS10630
uniprot id: F5YFL3
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

545695:TREAZ RS15570
gene id: 545695:TREAZ_RS15570
uniprot id: F5YDT8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

545695:TREAZ RS12970
gene id: 545695:TREAZ_RS12970
uniprot id: F5Y988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

545695:TREAZ RS12905
gene id: 545695:TREAZ_RS12905
uniprot id: F5Y974
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

545695:TREAZ RS00935
gene id: 545695:TREAZ_RS00935
uniprot id: F5Y9B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

545695:TREAZ RS00950
gene id: 545695:TREAZ_RS00950
uniprot id: F5Y9C2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS06785
gene id: 545695:TREAZ_RS06785
uniprot id: F5Y8Y7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

545695:TREAZ RS00390
gene id: 545695:TREAZ_RS00390
uniprot id: F5Y846
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

545695:TREAZ RS10815
gene id: 545695:TREAZ_RS10815
uniprot id: F5YG58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS02335
gene id: 545695:TREAZ_RS02335
uniprot id: F5YBG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS15420
gene id: 545695:TREAZ_RS15420
uniprot id: F5YDQ7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

545695:TREAZ RS10250
gene id: 545695:TREAZ_RS10250
uniprot id: F5YEX8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

545695:TREAZ RS16255
gene id: 545695:TREAZ_RS16255
uniprot id: F5YF36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS08405
gene id: 545695:TREAZ_RS08405
uniprot id: F5YBM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

545695:TREAZ RS00190
gene id: 545695:TREAZ_RS00190
uniprot id: F5Y806
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

545695:TREAZ RS11590
gene id: 545695:TREAZ_RS11590
uniprot id: F5Y7A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS15665
gene id: 545695:TREAZ_RS15665
uniprot id: F5YDV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

545695:TREAZ RS10145
gene id: 545695:TREAZ_RS10145
uniprot id: F5YEV8
names: Similarity
messages: Belongs to the MotB family.

545695:TREAZ RS04355
gene id: 545695:TREAZ_RS04355
uniprot id: F5YF99
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

545695:TREAZ RS11995
gene id: 545695:TREAZ_RS11995
uniprot id: F5Y7T0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

545695:TREAZ RS00930
gene id: 545695:TREAZ_RS00930
uniprot id: F5Y9B8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

545695:TREAZ RS12405
gene id: 545695:TREAZ_RS12405
uniprot id: F5Y8H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

545695:TREAZ RS12160
gene id: 545695:TREAZ_RS12160
uniprot id: F5Y7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

545695:TREAZ RS08435
gene id: 545695:TREAZ_RS08435
uniprot id: F5YBN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

545695:TREAZ RS15230
gene id: 545695:TREAZ_RS15230
uniprot id: F5YD67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

545695:TREAZ RS15705
gene id: 545695:TREAZ_RS15705
uniprot id: F5YEC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

545695:TREAZ RS11595
gene id: 545695:TREAZ_RS11595
uniprot id: F5Y7B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS08020
gene id: 545695:TREAZ_RS08020
uniprot id: F5YAZ8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS14750
gene id: 545695:TREAZ_RS14750
uniprot id: F5YCG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

545695:TREAZ RS10985
gene id: 545695:TREAZ_RS10985
uniprot id: F5YG90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS11760
gene id: 545695:TREAZ_RS11760
uniprot id: F5Y7E4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

545695:TREAZ RS01360
gene id: 545695:TREAZ_RS01360
uniprot id: F5YA09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

545695:TREAZ RS11855
gene id: 545695:TREAZ_RS11855
uniprot id: F5Y7G2
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

545695:TREAZ RS03360
gene id: 545695:TREAZ_RS03360
uniprot id: F5YDD7
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS10460
gene id: 545695:TREAZ_RS10460
uniprot id: F5YFH6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

545695:TREAZ RS00560
gene id: 545695:TREAZ_RS00560
uniprot id: F5Y8N6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

545695:TREAZ RS04910
gene id: 545695:TREAZ_RS04910
uniprot id: F5YG15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

545695:TREAZ RS00940
gene id: 545695:TREAZ_RS00940
uniprot id: F5Y9C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

545695:TREAZ RS04940
gene id: 545695:TREAZ_RS04940
uniprot id: F5YG21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

545695:TREAZ RS08420
gene id: 545695:TREAZ_RS08420
uniprot id: F5YBN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

545695:TREAZ RS15670
gene id: 545695:TREAZ_RS15670
uniprot id: F5YDV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

545695:TREAZ RS03930
gene id: 545695:TREAZ_RS03930
uniprot id: F5YEL3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

545695:TREAZ RS10140
gene id: 545695:TREAZ_RS10140
uniprot id: F5YEV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

545695:TREAZ RS10550
gene id: 545695:TREAZ_RS10550
uniprot id: F5YFJ5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

545695:TREAZ RS02415
gene id: 545695:TREAZ_RS02415
uniprot id: F5YBY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS04235
gene id: 545695:TREAZ_RS04235
uniprot id: F5YF76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS13035
gene id: 545695:TREAZ_RS13035
uniprot id: F5Y9Q2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

545695:TREAZ RS11250
gene id: 545695:TREAZ_RS11250
uniprot id: F5Y6W5
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

545695:TREAZ RS08755
gene id: 545695:TREAZ_RS08755
uniprot id: F5YC98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

545695:TREAZ RS07955
gene id: 545695:TREAZ_RS07955
uniprot id: F5YAY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS07615
gene id: 545695:TREAZ_RS07615
uniprot id: F5YAB3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

545695:TREAZ RS07595
gene id: 545695:TREAZ_RS07595
uniprot id: F5YAA9
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

545695:TREAZ RS02995
gene id: 545695:TREAZ_RS02995
uniprot id: F5YCQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

545695:TREAZ RS08735
gene id: 545695:TREAZ_RS08735
uniprot id: F5YC95
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

545695:TREAZ RS11410
gene id: 545695:TREAZ_RS11410
uniprot id: F5Y6Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS14525
gene id: 545695:TREAZ_RS14525
uniprot id: F5YCB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS13865
gene id: 545695:TREAZ_RS13865
uniprot id: F5YB31
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

545695:TREAZ RS09980
gene id: 545695:TREAZ_RS09980
uniprot id: F5YES6
names: Subcellular Location Annotation
messages: Periplasm

545695:TREAZ RS14490
gene id: 545695:TREAZ_RS14490
uniprot id: F5YBW1
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS06840
gene id: 545695:TREAZ_RS06840
uniprot id: F5Y8Z8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

545695:TREAZ RS03980
gene id: 545695:TREAZ_RS03980
uniprot id: F5YEM4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

545695:TREAZ RS09365
gene id: 545695:TREAZ_RS09365
uniprot id: F5YDI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

545695:TREAZ RS16030
gene id: 545695:TREAZ_RS16030
uniprot id: F5YEI9
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS03595
gene id: 545695:TREAZ_RS03595
uniprot id: F5YDY8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

545695:TREAZ RS14795
gene id: 545695:TREAZ_RS14795
uniprot id: F5YCH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

545695:TREAZ RS15675
gene id: 545695:TREAZ_RS15675
uniprot id: F5YDV8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

545695:TREAZ RS10690
gene id: 545695:TREAZ_RS10690
uniprot id: F5YFM8
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

545695:TREAZ RS03525
gene id: 545695:TREAZ_RS03525
uniprot id: F5YDX5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

545695:TREAZ RS13025
gene id: 545695:TREAZ_RS13025
uniprot id: F5Y9Q0
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

545695:TREAZ RS13595
gene id: 545695:TREAZ_RS13595
uniprot id: F5YAG9
names: Subcellular Location Annotation
messages: Cytoplasm

545695:TREAZ RS10205
gene id: 545695:TREAZ_RS10205
uniprot id: F5YEX0
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS16215
gene id: 545695:TREAZ_RS16215
uniprot id: F5YF28
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS15625
gene id: 545695:TREAZ_RS15625
uniprot id: F5YDU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

545695:TREAZ RS11650
gene id: 545695:TREAZ_RS11650
uniprot id: F5Y7C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

545695:TREAZ RS16695
gene id: 545695:TREAZ_RS16695
uniprot id: F5YFT0
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS08710
gene id: 545695:TREAZ_RS08710
uniprot id: F5YC89
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

545695:TREAZ RS14095
gene id: 545695:TREAZ_RS14095
uniprot id: F5YB78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

545695:TREAZ RS06480
gene id: 545695:TREAZ_RS06480
uniprot id: F5Y8C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS15110
gene id: 545695:TREAZ_RS15110
uniprot id: F5YD42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

545695:TREAZ RS16885
gene id: 545695:TREAZ_RS16885
uniprot id: F5YGC2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

545695:TREAZ RS06740
gene id: 545695:TREAZ_RS06740
uniprot id: F5Y8X9
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS01770
gene id: 545695:TREAZ_RS01770
uniprot id: F5YAP0
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS11940
gene id: 545695:TREAZ_RS11940
uniprot id: F5Y7R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS10100
gene id: 545695:TREAZ_RS10100
uniprot id: F5YEU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

545695:TREAZ RS09360
gene id: 545695:TREAZ_RS09360
uniprot id: F5YDI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

545695:TREAZ RS10865
gene id: 545695:TREAZ_RS10865
uniprot id: F5YG66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

545695:TREAZ RS02565
gene id: 545695:TREAZ_RS02565
uniprot id: F5YC10
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

545695:TREAZ RS00545
gene id: 545695:TREAZ_RS00545
uniprot id: F5Y8N3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

545695:TREAZ RS12100
gene id: 545695:TREAZ_RS12100
uniprot id: F5Y7V2
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

545695:TREAZ RS05290
gene id: 545695:TREAZ_RS05290
uniprot id: F5Y6Q9
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

545695:TREAZ RS06720
gene id: 545695:TREAZ_RS06720
uniprot id: F5Y8X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

545695:TREAZ RS00755
gene id: 545695:TREAZ_RS00755
uniprot id: F5Y8S6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

545695:TREAZ RS04435
gene id: 545695:TREAZ_RS04435
uniprot id: F5YFB4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

545695:TREAZ RS10270
gene id: 545695:TREAZ_RS10270
uniprot id: F5YEY2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

545695:TREAZ RS15605
gene id: 545695:TREAZ_RS15605
uniprot id: F5YDU4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

545695:TREAZ RS13030
gene id: 545695:TREAZ_RS13030
uniprot id: F5Y9Q1
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

545695:TREAZ RS10930
gene id: 545695:TREAZ_RS10930
uniprot id: F5YG80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

545695:TREAZ RS01500
gene id: 545695:TREAZ_RS01500
uniprot id: F5YA36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS03590
gene id: 545695:TREAZ_RS03590
uniprot id: F5YDY7
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

545695:TREAZ RS09535
gene id: 545695:TREAZ_RS09535
uniprot id: F5YDM0
names: Similarity
messages: Belongs to the pirin family.

545695:TREAZ RS12040
gene id: 545695:TREAZ_RS12040
uniprot id: F5Y7U0
names: Similarity
messages: Belongs to the acetyltransferase family. ArgA subfamily.

545695:TREAZ RS09000
gene id: 545695:TREAZ_RS09000
uniprot id: F5YCV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

545695:TREAZ RS10770
gene id: 545695:TREAZ_RS10770
uniprot id: F5YG49
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS16950
gene id: 545695:TREAZ_RS16950
uniprot id: F5YGD5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

545695:TREAZ RS10765
gene id: 545695:TREAZ_RS10765
uniprot id: F5YG48
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS08910
gene id: 545695:TREAZ_RS08910
uniprot id: F5YCT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

545695:TREAZ RS06395
gene id: 545695:TREAZ_RS06395
uniprot id: F5Y8A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

545695:TREAZ RS05225
gene id: 545695:TREAZ_RS05225
uniprot id: F5Y6P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Monomer.

545695:TREAZ RS02065
gene id: 545695:TREAZ_RS02065
uniprot id: F5YBB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

545695:TREAZ RS12865
gene id: 545695:TREAZ_RS12865
uniprot id: F5Y966
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS02920
gene id: 545695:TREAZ_RS02920
uniprot id: F5YCN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

545695:TREAZ RS04840
gene id: 545695:TREAZ_RS04840
uniprot id: F5YG03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

545695:TREAZ RS10350
gene id: 545695:TREAZ_RS10350
uniprot id: F5YEZ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

545695:TREAZ RS06280
gene id: 545695:TREAZ_RS06280
uniprot id: F5Y882
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

545695:TREAZ RS01660
gene id: 545695:TREAZ_RS01660
uniprot id: F5YAL8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

545695:TREAZ RS13500
gene id: 545695:TREAZ_RS13500
uniprot id: F5YAE9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

545695:TREAZ RS05570
gene id: 545695:TREAZ_RS05570
uniprot id: F5Y743
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

545695:TREAZ RS06015
gene id: 545695:TREAZ_RS06015
uniprot id: F5Y7M0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

545695:TREAZ RS04785
gene id: 545695:TREAZ_RS04785
uniprot id: F5YFZ3
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

545695:TREAZ RS14480
gene id: 545695:TREAZ_RS14480
uniprot id: F5YBV9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

545695:TREAZ RS08095
gene id: 545695:TREAZ_RS08095
uniprot id: F5YBG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

545695:TREAZ RS00160
gene id: 545695:TREAZ_RS00160
uniprot id: F5Y801
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS15610
gene id: 545695:TREAZ_RS15610
uniprot id: F5YDU5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

545695:TREAZ RS10845
gene id: 545695:TREAZ_RS10845
uniprot id: F5YG62
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS08700
gene id: 545695:TREAZ_RS08700
uniprot id: F5YC87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

545695:TREAZ RS14830
gene id: 545695:TREAZ_RS14830
uniprot id: F5YCH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

545695:TREAZ RS15695
gene id: 545695:TREAZ_RS15695
uniprot id: F5YEB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

545695:TREAZ RS13575
gene id: 545695:TREAZ_RS13575
uniprot id: F5YAG5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

545695:TREAZ RS10110
gene id: 545695:TREAZ_RS10110
uniprot id: F5YEV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

545695:TREAZ RS12445
gene id: 545695:TREAZ_RS12445
uniprot id: F5Y8H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

545695:TREAZ RS03610
gene id: 545695:TREAZ_RS03610
uniprot id: F5YDZ1
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

545695:TREAZ RS12965
gene id: 545695:TREAZ_RS12965
uniprot id: F5Y987
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

545695:TREAZ RS11105
gene id: 545695:TREAZ_RS11105
uniprot id: F5Y6T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS04120
gene id: 545695:TREAZ_RS04120
uniprot id: F5YEQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

545695:TREAZ RS13910
gene id: 545695:TREAZ_RS13910
uniprot id: F5YB41
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

545695:TREAZ RS09930
gene id: 545695:TREAZ_RS09930
uniprot id: F5YEB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS08820
gene id: 545695:TREAZ_RS08820
uniprot id: F5YCB2
names: Similarity
messages: Belongs to the hemerythrin family.

545695:TREAZ RS00795
gene id: 545695:TREAZ_RS00795
uniprot id: F5Y8T4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

545695:TREAZ RS13125
gene id: 545695:TREAZ_RS13125
uniprot id: F5Y9S0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

545695:TREAZ RS10130
gene id: 545695:TREAZ_RS10130
uniprot id: F5YEV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

545695:TREAZ RS13855
gene id: 545695:TREAZ_RS13855
uniprot id: F5YB29
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

545695:TREAZ RS15345
gene id: 545695:TREAZ_RS15345
uniprot id: F5YDP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

545695:TREAZ RS02125
gene id: 545695:TREAZ_RS02125
uniprot id: F5YBC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

545695:TREAZ RS10045
gene id: 545695:TREAZ_RS10045
uniprot id: F5YET8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS15615
gene id: 545695:TREAZ_RS15615
uniprot id: F5YDU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

545695:TREAZ RS01005
gene id: 545695:TREAZ_RS01005
uniprot id: F5Y9D3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

545695:TREAZ RS01745
gene id: 545695:TREAZ_RS01745
uniprot id: F5YAN6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS13115
gene id: 545695:TREAZ_RS13115
uniprot id: F5Y9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

545695:TREAZ RS15830
gene id: 545695:TREAZ_RS15830
uniprot id: F5YEE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

545695:TREAZ RS00115
gene id: 545695:TREAZ_RS00115
uniprot id: F5Y7Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS15880
gene id: 545695:TREAZ_RS15880
uniprot id: F5YEF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

545695:TREAZ RS10820
gene id: 545695:TREAZ_RS10820
uniprot id: F5YG59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS16605
gene id: 545695:TREAZ_RS16605
uniprot id: F5YFR0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

545695:TREAZ RS10855
gene id: 545695:TREAZ_RS10855
uniprot id: F5YG64
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS07085
gene id: 545695:TREAZ_RS07085
uniprot id: F5Y9K5
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS09020
gene id: 545695:TREAZ_RS09020
uniprot id: F5YCW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

545695:TREAZ RS15090
gene id: 545695:TREAZ_RS15090
uniprot id: F5YD38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

545695:TREAZ RS09740
gene id: 545695:TREAZ_RS09740
uniprot id: F5YE74
names: Subcellular Location Annotation
messages: Nucleus

545695:TREAZ RS11505
gene id: 545695:TREAZ_RS11505
uniprot id: F5Y794
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

545695:TREAZ RS06780
gene id: 545695:TREAZ_RS06780
uniprot id: F5Y8Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

545695:TREAZ RS02720
gene id: 545695:TREAZ_RS02720
uniprot id: F5YC36
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

545695:TREAZ RS11125
gene id: 545695:TREAZ_RS11125
uniprot id: F5Y6T8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

545695:TREAZ RS08430
gene id: 545695:TREAZ_RS08430
uniprot id: F5YBN3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

545695:TREAZ RS02220
gene id: 545695:TREAZ_RS02220
uniprot id: F5YBE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

545695:TREAZ RS09105
gene id: 545695:TREAZ_RS09105
uniprot id: F5YCX8
names: Similarity
messages: Belongs to the UPF0175 family.

545695:TREAZ RS04625
gene id: 545695:TREAZ_RS04625
uniprot id: F5YFV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

545695:TREAZ RS16025
gene id: 545695:TREAZ_RS16025
uniprot id: F5YEI8
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS09955
gene id: 545695:TREAZ_RS09955
uniprot id: F5YES1
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

545695:TREAZ RS10420
gene id: 545695:TREAZ_RS10420
uniprot id: F5YFG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

545695:TREAZ RS03900
gene id: 545695:TREAZ_RS03900
uniprot id: F5YEK7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

545695:TREAZ RS13665
gene id: 545695:TREAZ_RS13665
uniprot id: F5YAI4
names: Similarity
messages: Belongs to the CapA family.

545695:TREAZ RS16545
gene id: 545695:TREAZ_RS16545
uniprot id: F5YFP7
names: Similarity
messages: Belongs to the UPF0102 family.

545695:TREAZ RS08450
gene id: 545695:TREAZ_RS08450
uniprot id: F5YBN7
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS10430
gene id: 545695:TREAZ_RS10430
uniprot id: F5YFG8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

545695:TREAZ RS17110
gene id: 545695:TREAZ_RS17110
uniprot id: F5YGH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS12870
gene id: 545695:TREAZ_RS12870
uniprot id: F5Y967
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS00005
gene id: 545695:TREAZ_RS00005
uniprot id: F5Y7G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

545695:TREAZ RS08455
gene id: 545695:TREAZ_RS08455
uniprot id: F5YBN8
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS14790
gene id: 545695:TREAZ_RS14790
uniprot id: F5YCH1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

545695:TREAZ RS00475
gene id: 545695:TREAZ_RS00475
uniprot id: F5Y8L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

545695:TREAZ RS05245
gene id: 545695:TREAZ_RS05245
uniprot id: F5Y6Q0
names: Similarity
messages: Belongs to the fabD family.

545695:TREAZ RS06485
gene id: 545695:TREAZ_RS06485
uniprot id: F5Y8C3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

545695:TREAZ RS11465
gene id: 545695:TREAZ_RS11465
uniprot id: F5Y708
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

545695:TREAZ RS10585
gene id: 545695:TREAZ_RS10585
uniprot id: F5YFK2
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

545695:TREAZ RS14285
gene id: 545695:TREAZ_RS14285
uniprot id: F5YBS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

545695:TREAZ RS04675
gene id: 545695:TREAZ_RS04675
uniprot id: F5YFX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS08310
gene id: 545695:TREAZ_RS08310
uniprot id: F5YBK7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS04765
gene id: 545695:TREAZ_RS04765
uniprot id: F5YFY9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

545695:TREAZ RS06090
gene id: 545695:TREAZ_RS06090
uniprot id: F5Y7N8
names: Similarity
messages: Belongs to the peptidase C40 family.

545695:TREAZ RS04305
gene id: 545695:TREAZ_RS04305
uniprot id: F5YF89
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

545695:TREAZ RS11655
gene id: 545695:TREAZ_RS11655
uniprot id: F5Y7C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

545695:TREAZ RS15095
gene id: 545695:TREAZ_RS15095
uniprot id: F5YD39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

545695:TREAZ RS05220
gene id: 545695:TREAZ_RS05220
uniprot id: F5Y6P5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

545695:TREAZ RS04155
gene id: 545695:TREAZ_RS04155
uniprot id: F5YER1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

545695:TREAZ RS16350
gene id: 545695:TREAZ_RS16350
uniprot id: F5YF54
names: Similarity
messages: Belongs to the ArsC family.

545695:TREAZ RS11385
gene id: 545695:TREAZ_RS11385
uniprot id: F5Y6Z1
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS13605
gene id: 545695:TREAZ_RS13605
uniprot id: F5YAH1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

545695:TREAZ RS07695
gene id: 545695:TREAZ_RS07695
uniprot id: F5YAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

545695:TREAZ RS08445
gene id: 545695:TREAZ_RS08445
uniprot id: F5YBN6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

545695:TREAZ RS07740
gene id: 545695:TREAZ_RS07740
uniprot id: F5YAU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

545695:TREAZ RS14290
gene id: 545695:TREAZ_RS14290
uniprot id: F5YBS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

545695:TREAZ RS16905
gene id: 545695:TREAZ_RS16905
uniprot id: F5YGC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

545695:TREAZ RS00155
gene id: 545695:TREAZ_RS00155
uniprot id: F5Y800
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

545695:TREAZ RS11430
gene id: 545695:TREAZ_RS11430
uniprot id: F5Y700
names: Similarity
messages: Belongs to the BMP lipoprotein family.

545695:TREAZ RS04935
gene id: 545695:TREAZ_RS04935
uniprot id: F5YG20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

545695:TREAZ RS11065
gene id: 545695:TREAZ_RS11065
uniprot id: F5YGA6
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

545695:TREAZ RS14205
gene id: 545695:TREAZ_RS14205
uniprot id: F5YBQ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

545695:TREAZ RS15035
gene id: 545695:TREAZ_RS15035
uniprot id: F5YD28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

545695:TREAZ RS14255
gene id: 545695:TREAZ_RS14255
uniprot id: F5YBR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS12525
gene id: 545695:TREAZ_RS12525
uniprot id: F5Y8J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

545695:TREAZ RS11735
gene id: 545695:TREAZ_RS11735
uniprot id: F5Y7D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

545695:TREAZ RS01865
gene id: 545695:TREAZ_RS01865
uniprot id: F5YAR3
names: Similarity
messages: Belongs to the peptidase C40 family.

545695:TREAZ RS16805
gene id: 545695:TREAZ_RS16805
uniprot id: F5YFV1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

545695:TREAZ RS10480
gene id: 545695:TREAZ_RS10480
uniprot id: F5YFI0
names: Similarity
messages: Belongs to the aldose epimerase family.

545695:TREAZ RS07515
gene id: 545695:TREAZ_RS07515
uniprot id: F5YA94
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

545695:TREAZ RS16125
gene id: 545695:TREAZ_RS16125
uniprot id: F5YF09
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

545695:TREAZ RS09845
gene id: 545695:TREAZ_RS09845
uniprot id: F5YE96
names: Similarity
messages: Belongs to the TPP enzyme family.

545695:TREAZ RS16290
gene id: 545695:TREAZ_RS16290
uniprot id: F5YF42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS17545
gene id: 545695:TREAZ_RS17545
uniprot id: F5YDP8
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

545695:TREAZ RS04205
gene id: 545695:TREAZ_RS04205
uniprot id: F5YER8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

545695:TREAZ RS08490
gene id: 545695:TREAZ_RS08490
uniprot id: F5YC42
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS15850
gene id: 545695:TREAZ_RS15850
uniprot id: F5YEF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

545695:TREAZ RS09415
gene id: 545695:TREAZ_RS09415
uniprot id: F5YDJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

545695:TREAZ RS04335
gene id: 545695:TREAZ_RS04335
uniprot id: F5YF95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS06240
gene id: 545695:TREAZ_RS06240
uniprot id: F5Y874
names: Similarity
messages: Belongs to the UPF0235 family.

545695:TREAZ RS06610
gene id: 545695:TREAZ_RS06610
uniprot id: F5Y8V4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

545695:TREAZ RS03675
gene id: 545695:TREAZ_RS03675
uniprot id: F5YE05
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

545695:TREAZ RS15835
gene id: 545695:TREAZ_RS15835
uniprot id: F5YEE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

545695:TREAZ RS08370
gene id: 545695:TREAZ_RS08370
uniprot id: F5YBM1
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

545695:TREAZ RS14925
gene id: 545695:TREAZ_RS14925
uniprot id: F5YD07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

545695:TREAZ RS04280
gene id: 545695:TREAZ_RS04280
uniprot id: F5YF83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

545695:TREAZ RS13350
gene id: 545695:TREAZ_RS13350
uniprot id: F5Y9W8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

545695:TREAZ RS14845
gene id: 545695:TREAZ_RS14845
uniprot id: F5YCI2
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS16195
gene id: 545695:TREAZ_RS16195
uniprot id: F5YF24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

545695:TREAZ RS00255
gene id: 545695:TREAZ_RS00255
uniprot id: F5Y819
names: Similarity
messages: Belongs to the glycosyl hydrolase.

545695:TREAZ RS09800
gene id: 545695:TREAZ_RS09800
uniprot id: F5YE87
names: Similarity
messages: Belongs to the ClpA/ClpB family.

545695:TREAZ RS12285
gene id: 545695:TREAZ_RS12285
uniprot id: F5Y8E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

545695:TREAZ RS08590
gene id: 545695:TREAZ_RS08590
uniprot id: F5YC64
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

545695:TREAZ RS10950
gene id: 545695:TREAZ_RS10950
uniprot id: F5YG84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

545695:TREAZ RS14385
gene id: 545695:TREAZ_RS14385
uniprot id: F5YBU0
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.

545695:TREAZ RS01080
gene id: 545695:TREAZ_RS01080
uniprot id: F5Y9E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS15405
gene id: 545695:TREAZ_RS15405
uniprot id: F5YDQ5
names: Similarity
messages: Belongs to the peptidase S41A family.

545695:TREAZ RS15340
gene id: 545695:TREAZ_RS15340
uniprot id: F5YDP2
names: Similarity
messages: Belongs to the threonine synthase family.

545695:TREAZ RS09775
gene id: 545695:TREAZ_RS09775
uniprot id: F5YE82
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

545695:TREAZ RS14865
gene id: 545695:TREAZ_RS14865
uniprot id: F5YCI6
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

545695:TREAZ RS16930
gene id: 545695:TREAZ_RS16930
uniprot id: F5YGD1
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS00595
gene id: 545695:TREAZ_RS00595
uniprot id: F5Y8P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS13545
gene id: 545695:TREAZ_RS13545
uniprot id: F5YAF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

545695:TREAZ RS07545
gene id: 545695:TREAZ_RS07545
uniprot id: F5YA99
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS04475
gene id: 545695:TREAZ_RS04475
uniprot id: F5YFC2
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

545695:TREAZ RS14725
gene id: 545695:TREAZ_RS14725
uniprot id: F5YCF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

545695:TREAZ RS12235
gene id: 545695:TREAZ_RS12235
uniprot id: F5Y7X9
names: Similarity
messages: Belongs to the leucine-binding protein family.

545695:TREAZ RS14600
gene id: 545695:TREAZ_RS14600
uniprot id: F5YCD1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

545695:TREAZ RS06715
gene id: 545695:TREAZ_RS06715
uniprot id: F5Y8X4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

545695:TREAZ RS00770
gene id: 545695:TREAZ_RS00770
uniprot id: F5Y8S9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

545695:TREAZ RS04400
gene id: 545695:TREAZ_RS04400
uniprot id: F5YFA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

545695:TREAZ RS09625
gene id: 545695:TREAZ_RS09625
uniprot id: F5YE46
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS15430
gene id: 545695:TREAZ_RS15430
uniprot id: F5YDQ9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

545695:TREAZ RS01475
gene id: 545695:TREAZ_RS01475
uniprot id: F5YA31
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

545695:TREAZ RS00695
gene id: 545695:TREAZ_RS00695
uniprot id: F5Y8R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

545695:TREAZ RS14190
gene id: 545695:TREAZ_RS14190
uniprot id: F5YBQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS11660
gene id: 545695:TREAZ_RS11660
uniprot id: F5Y7C5
names: Similarity
messages: Belongs to the peptidase S1C family.

545695:TREAZ RS07345
gene id: 545695:TREAZ_RS07345
uniprot id: F5YA59
names: Similarity
messages: Belongs to the UMP kinase family.

545695:TREAZ RS08440
gene id: 545695:TREAZ_RS08440
uniprot id: F5YBN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

545695:TREAZ RS06800
gene id: 545695:TREAZ_RS06800
uniprot id: F5Y8Z0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

545695:TREAZ RS06855
gene id: 545695:TREAZ_RS06855
uniprot id: F5Y901
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS15220
gene id: 545695:TREAZ_RS15220
uniprot id: F5YD64
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS03340
gene id: 545695:TREAZ_RS03340
uniprot id: F5YDD4
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

545695:TREAZ RS08895
gene id: 545695:TREAZ_RS08895
uniprot id: F5YCT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

545695:TREAZ RS08880
gene id: 545695:TREAZ_RS08880
uniprot id: F5YCT2
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS00460
gene id: 545695:TREAZ_RS00460
uniprot id: F5Y8L5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS10600
gene id: 545695:TREAZ_RS10600
uniprot id: F5YFK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

545695:TREAZ RS16570
gene id: 545695:TREAZ_RS16570
uniprot id: F5YFQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

545695:TREAZ RS13965
gene id: 545695:TREAZ_RS13965
uniprot id: F5YB51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

545695:TREAZ RS08670
gene id: 545695:TREAZ_RS08670
uniprot id: F5YC81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

545695:TREAZ RS12520
gene id: 545695:TREAZ_RS12520
uniprot id: F5Y8J3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

545695:TREAZ RS05365
gene id: 545695:TREAZ_RS05365
uniprot id: F5Y6S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS01665
gene id: 545695:TREAZ_RS01665
uniprot id: F5YAL9
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS10210
gene id: 545695:TREAZ_RS10210
uniprot id: F5YEX1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

545695:TREAZ RS02305
gene id: 545695:TREAZ_RS02305
uniprot id: F5YBF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS10135
gene id: 545695:TREAZ_RS10135
uniprot id: F5YEV6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

545695:TREAZ RS03310
gene id: 545695:TREAZ_RS03310
uniprot id: F5YDC7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

545695:TREAZ RS11170
gene id: 545695:TREAZ_RS11170
uniprot id: F5Y6U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS08040
gene id: 545695:TREAZ_RS08040
uniprot id: F5YB02
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

545695:TREAZ RS12225
gene id: 545695:TREAZ_RS12225
uniprot id: F5Y7X7
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS14835
gene id: 545695:TREAZ_RS14835
uniprot id: F5YCI0
names: Similarity
messages: Belongs to the UPF0423 family.

545695:TREAZ RS11720
gene id: 545695:TREAZ_RS11720
uniprot id: F5Y7D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

545695:TREAZ RS05285
gene id: 545695:TREAZ_RS05285
uniprot id: F5Y6Q8
names: Similarity
messages: Belongs to the RecJ family.

545695:TREAZ RS00200
gene id: 545695:TREAZ_RS00200
uniprot id: F5Y808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS05745
gene id: 545695:TREAZ_RS05745
uniprot id: F5Y779
names: Similarity
messages: Belongs to the hexokinase family.

545695:TREAZ RS13715
gene id: 545695:TREAZ_RS13715
uniprot id: F5YAJ3
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS00575
gene id: 545695:TREAZ_RS00575
uniprot id: F5Y8N8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

545695:TREAZ RS08885
gene id: 545695:TREAZ_RS08885
uniprot id: F5YCT3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

545695:TREAZ RS08090
gene id: 545695:TREAZ_RS08090
uniprot id: F5YBG8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

545695:TREAZ RS15690
gene id: 545695:TREAZ_RS15690
uniprot id: F5YEB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

545695:TREAZ RS07365
gene id: 545695:TREAZ_RS07365
uniprot id: F5YA63
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

545695:TREAZ RS13295
gene id: 545695:TREAZ_RS13295
uniprot id: F5Y9V7
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS16135
gene id: 545695:TREAZ_RS16135
uniprot id: F5YF11
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

545695:TREAZ RS12510
gene id: 545695:TREAZ_RS12510
uniprot id: F5Y8J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

545695:TREAZ RS08870
gene id: 545695:TREAZ_RS08870
uniprot id: F5YCT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

545695:TREAZ RS16835
gene id: 545695:TREAZ_RS16835
uniprot id: F5YFV6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

545695:TREAZ RS01765
gene id: 545695:TREAZ_RS01765
uniprot id: F5YAN9
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

545695:TREAZ RS06730
gene id: 545695:TREAZ_RS06730
uniprot id: F5Y8X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

545695:TREAZ RS15485
gene id: 545695:TREAZ_RS15485
uniprot id: F5YDR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

545695:TREAZ RS02285
gene id: 545695:TREAZ_RS02285
uniprot id: F5YBF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

545695:TREAZ RS05840
gene id: 545695:TREAZ_RS05840
uniprot id: F5Y7I5
names: Similarity
messages: Belongs to the ParB family.

545695:TREAZ RS12020
gene id: 545695:TREAZ_RS12020
uniprot id: F5Y7T5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

545695:TREAZ RS03000
gene id: 545695:TREAZ_RS03000
uniprot id: F5YCQ3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

545695:TREAZ RS15100
gene id: 545695:TREAZ_RS15100
uniprot id: F5YD40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

545695:TREAZ RS10050
gene id: 545695:TREAZ_RS10050
uniprot id: F5YET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS01575
gene id: 545695:TREAZ_RS01575
uniprot id: F5YA49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS05100
gene id: 545695:TREAZ_RS05100
uniprot id: F5Y6M2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

545695:TREAZ RS08060
gene id: 545695:TREAZ_RS08060
uniprot id: F5YB06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

545695:TREAZ RS03885
gene id: 545695:TREAZ_RS03885
uniprot id: F5YEK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

545695:TREAZ RS14715
gene id: 545695:TREAZ_RS14715
uniprot id: F5YCF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

545695:TREAZ RS15330
gene id: 545695:TREAZ_RS15330
uniprot id: F5YDP0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

545695:TREAZ RS12945
gene id: 545695:TREAZ_RS12945
uniprot id: F5Y983
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

545695:TREAZ RS16200
gene id: 545695:TREAZ_RS16200
uniprot id: F5YF25
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS08080
gene id: 545695:TREAZ_RS08080
uniprot id: F5YB10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

545695:TREAZ RS09335
gene id: 545695:TREAZ_RS09335
uniprot id: F5YDI0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

545695:TREAZ RS08340
gene id: 545695:TREAZ_RS08340
uniprot id: F5YBL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS03405
gene id: 545695:TREAZ_RS03405
uniprot id: F5YDE6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

545695:TREAZ RS08680
gene id: 545695:TREAZ_RS08680
uniprot id: F5YC83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS08705
gene id: 545695:TREAZ_RS08705
uniprot id: F5YC88
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

545695:TREAZ RS07900
gene id: 545695:TREAZ_RS07900
uniprot id: F5YAX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

545695:TREAZ RS06385
gene id: 545695:TREAZ_RS06385
uniprot id: F5Y8A3
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS06520
gene id: 545695:TREAZ_RS06520
uniprot id: F5Y8C9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

545695:TREAZ RS14325
gene id: 545695:TREAZ_RS14325
uniprot id: F5YBS9
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

545695:TREAZ RS10005
gene id: 545695:TREAZ_RS10005
uniprot id: F5YET1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS14735
gene id: 545695:TREAZ_RS14735
uniprot id: F5YCG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

545695:TREAZ RS03915
gene id: 545695:TREAZ_RS03915
uniprot id: F5YEL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS11865
gene id: 545695:TREAZ_RS11865
uniprot id: F5Y7Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

545695:TREAZ RS04405
gene id: 545695:TREAZ_RS04405
uniprot id: F5YFA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

545695:TREAZ RS18520
gene id: 545695:TREAZ_RS18520
uniprot id: F5YBR3
names: Similarity
messages: Belongs to the P(II) protein family.

545695:TREAZ RS14195
gene id: 545695:TREAZ_RS14195
uniprot id: F5YBQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS08725
gene id: 545695:TREAZ_RS08725
uniprot id: F5YC93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

545695:TREAZ RS06285
gene id: 545695:TREAZ_RS06285
uniprot id: F5Y883
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

545695:TREAZ RS11380
gene id: 545695:TREAZ_RS11380
uniprot id: F5Y6Z0
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

545695:TREAZ RS16210
gene id: 545695:TREAZ_RS16210
uniprot id: F5YF27
names: Similarity
messages: Belongs to the GARS family.

545695:TREAZ RS10675
gene id: 545695:TREAZ_RS10675
uniprot id: F5YFM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

545695:TREAZ RS10095
gene id: 545695:TREAZ_RS10095
uniprot id: F5YEU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

545695:TREAZ RS13045
gene id: 545695:TREAZ_RS13045
uniprot id: F5Y9Q4
names: Similarity
messages: Belongs to the P(II) protein family.

545695:TREAZ RS06400
gene id: 545695:TREAZ_RS06400
uniprot id: F5Y8A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

545695:TREAZ RS12535
gene id: 545695:TREAZ_RS12535
uniprot id: F5Y8J6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

545695:TREAZ RS05510
gene id: 545695:TREAZ_RS05510
uniprot id: F5Y729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

545695:TREAZ RS04440
gene id: 545695:TREAZ_RS04440
uniprot id: F5YFB5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

545695:TREAZ RS04330
gene id: 545695:TREAZ_RS04330
uniprot id: F5YF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS12860
gene id: 545695:TREAZ_RS12860
uniprot id: F5Y965
names: Similarity
messages: Belongs to the DinB family.

545695:TREAZ RS01650
gene id: 545695:TREAZ_RS01650
uniprot id: F5YAL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS10590
gene id: 545695:TREAZ_RS10590
uniprot id: F5YFK4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS13455
gene id: 545695:TREAZ_RS13455
uniprot id: F5YAE1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

545695:TREAZ RS10240
gene id: 545695:TREAZ_RS10240
uniprot id: F5YEX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

545695:TREAZ RS00015
gene id: 545695:TREAZ_RS00015
uniprot id: F5Y7G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

545695:TREAZ RS06420
gene id: 545695:TREAZ_RS06420
uniprot id: F5Y8B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS11310
gene id: 545695:TREAZ_RS11310
uniprot id: F5Y6X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

545695:TREAZ RS06365
gene id: 545695:TREAZ_RS06365
uniprot id: F5Y899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS13980
gene id: 545695:TREAZ_RS13980
uniprot id: F5YB55
names: Similarity
messages: Belongs to the LarC family.

545695:TREAZ RS12365
gene id: 545695:TREAZ_RS12365
uniprot id: F5Y8G1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

545695:TREAZ RS03925
gene id: 545695:TREAZ_RS03925
uniprot id: F5YEL2
names: Similarity
messages: Belongs to the UPF0751 family.

545695:TREAZ RS03830
gene id: 545695:TREAZ_RS03830
uniprot id: F5YE34
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

545695:TREAZ RS08900
gene id: 545695:TREAZ_RS08900
uniprot id: F5YCT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

545695:TREAZ RS03415
gene id: 545695:TREAZ_RS03415
uniprot id: F5YDE9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

545695:TREAZ RS07105
gene id: 545695:TREAZ_RS07105
uniprot id: F5Y9K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS10670
gene id: 545695:TREAZ_RS10670
uniprot id: F5YFM4
names: Similarity
messages: Belongs to the LEA type 2 family.

545695:TREAZ RS17310
gene id: 545695:TREAZ_RS17310
uniprot id: F5Y6K7
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

545695:TREAZ RS08760
gene id: 545695:TREAZ_RS08760
uniprot id: F5YC99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

545695:TREAZ RS05930
gene id: 545695:TREAZ_RS05930
uniprot id: F5Y7K2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

545695:TREAZ RS02965
gene id: 545695:TREAZ_RS02965
uniprot id: F5YCP6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

545695:TREAZ RS13530
gene id: 545695:TREAZ_RS13530
uniprot id: F5YAF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS08510
gene id: 545695:TREAZ_RS08510
uniprot id: F5YC46
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

545695:TREAZ RS02970
gene id: 545695:TREAZ_RS02970
uniprot id: F5YCP7
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

545695:TREAZ RS05190
gene id: 545695:TREAZ_RS05190
uniprot id: F5Y6N9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

545695:TREAZ RS15495
gene id: 545695:TREAZ_RS15495
uniprot id: F5YDS1
names: Similarity
messages: Belongs to the DEAD box helicase family.

545695:TREAZ RS04825
gene id: 545695:TREAZ_RS04825
uniprot id: F5YG00
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

545695:TREAZ RS00715
gene id: 545695:TREAZ_RS00715
uniprot id: F5Y8R7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

545695:TREAZ RS15115
gene id: 545695:TREAZ_RS15115
uniprot id: F5YD43
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

545695:TREAZ RS04990
gene id: 545695:TREAZ_RS04990
uniprot id: F5YG33
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

545695:TREAZ RS11470
gene id: 545695:TREAZ_RS11470
uniprot id: F5Y709
names: Similarity
messages: Belongs to the UPF0758 family.

545695:TREAZ RS06320
gene id: 545695:TREAZ_RS06320
uniprot id: F5Y890
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS00365
gene id: 545695:TREAZ_RS00365
uniprot id: F5Y841
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

545695:TREAZ RS13860
gene id: 545695:TREAZ_RS13860
uniprot id: F5YB30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

545695:TREAZ RS07510
gene id: 545695:TREAZ_RS07510
uniprot id: F5YA93
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

545695:TREAZ RS16925
gene id: 545695:TREAZ_RS16925
uniprot id: F5YGD0
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS16325
gene id: 545695:TREAZ_RS16325
uniprot id: F5YF48
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

545695:TREAZ RS10465
gene id: 545695:TREAZ_RS10465
uniprot id: F5YFH7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

545695:TREAZ RS15985
gene id: 545695:TREAZ_RS15985
uniprot id: F5YEH9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

545695:TREAZ RS08660
gene id: 545695:TREAZ_RS08660
uniprot id: F5YC79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

545695:TREAZ RS16115
gene id: 545695:TREAZ_RS16115
uniprot id: F5YF07
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

545695:TREAZ RS05205
gene id: 545695:TREAZ_RS05205
uniprot id: F5Y6P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

545695:TREAZ RS05235
gene id: 545695:TREAZ_RS05235
uniprot id: F5Y6P8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

545695:TREAZ RS15190
gene id: 545695:TREAZ_RS15190
uniprot id: F5YD58
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

545695:TREAZ RS10310
gene id: 545695:TREAZ_RS10310
uniprot id: F5YEY9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

545695:TREAZ RS05150
gene id: 545695:TREAZ_RS05150
uniprot id: F5Y6N1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

545695:TREAZ RS16860
gene id: 545695:TREAZ_RS16860
uniprot id: F5YGB7
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

545695:TREAZ RS08390
gene id: 545695:TREAZ_RS08390
uniprot id: F5YBM5
names: Similarity
messages: Belongs to the Skp family.

545695:TREAZ RS15715
gene id: 545695:TREAZ_RS15715
uniprot id: F5YEC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

545695:TREAZ RS04835
gene id: 545695:TREAZ_RS04835
uniprot id: F5YG02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

545695:TREAZ RS11215
gene id: 545695:TREAZ_RS11215
uniprot id: F5Y6V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

545695:TREAZ RS06815
gene id: 545695:TREAZ_RS06815
uniprot id: F5Y8Z3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

545695:TREAZ RS04700
gene id: 545695:TREAZ_RS04700
uniprot id: F5YFX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS16880
gene id: 545695:TREAZ_RS16880
uniprot id: F5YGC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS13300
gene id: 545695:TREAZ_RS13300
uniprot id: F5Y9V8
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS11970
gene id: 545695:TREAZ_RS11970
uniprot id: F5Y7S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

545695:TREAZ RS01150
gene id: 545695:TREAZ_RS01150
uniprot id: F5Y9G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

545695:TREAZ RS00765
gene id: 545695:TREAZ_RS00765
uniprot id: F5Y8S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

545695:TREAZ RS00905
gene id: 545695:TREAZ_RS00905
uniprot id: F5Y9B3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

545695:TREAZ RS14045
gene id: 545695:TREAZ_RS14045
uniprot id: F5YB69
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

545695:TREAZ RS12875
gene id: 545695:TREAZ_RS12875
uniprot id: F5Y968
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS15915
gene id: 545695:TREAZ_RS15915
uniprot id: F5YEG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

545695:TREAZ RS02625
gene id: 545695:TREAZ_RS02625
uniprot id: F5YC22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

545695:TREAZ RS02975
gene id: 545695:TREAZ_RS02975
uniprot id: F5YCP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

545695:TREAZ RS13650
gene id: 545695:TREAZ_RS13650
uniprot id: F5YAI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS13600
gene id: 545695:TREAZ_RS13600
uniprot id: F5YAH0
names: Similarity
messages: Belongs to the YggT family.

545695:TREAZ RS03095
gene id: 545695:TREAZ_RS03095
uniprot id: F5YCS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

545695:TREAZ RS08800
gene id: 545695:TREAZ_RS08800
uniprot id: F5YCA8
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

545695:TREAZ RS04960
gene id: 545695:TREAZ_RS04960
uniprot id: F5YG25
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

545695:TREAZ RS06950
gene id: 545695:TREAZ_RS06950
uniprot id: F5Y9H9
names: Similarity
messages: Belongs to the TrpR family.

545695:TREAZ RS00435
gene id: 545695:TREAZ_RS00435
uniprot id: F5Y857
names: Similarity
messages: Belongs to the thioredoxin family.

545695:TREAZ RS09010
gene id: 545695:TREAZ_RS09010
uniprot id: F5YCV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

545695:TREAZ RS11725
gene id: 545695:TREAZ_RS11725
uniprot id: F5Y7D7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

545695:TREAZ RS03020
gene id: 545695:TREAZ_RS03020
uniprot id: F5YCQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

545695:TREAZ RS12230
gene id: 545695:TREAZ_RS12230
uniprot id: F5Y7X8
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS06980
gene id: 545695:TREAZ_RS06980
uniprot id: F5Y9I5
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

545695:TREAZ RS16020
gene id: 545695:TREAZ_RS16020
uniprot id: F5YEI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

545695:TREAZ RS02800
gene id: 545695:TREAZ_RS02800
uniprot id: F5YCL1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

545695:TREAZ RS15730
gene id: 545695:TREAZ_RS15730
uniprot id: F5YEC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS13040
gene id: 545695:TREAZ_RS13040
uniprot id: F5Y9Q3
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

545695:TREAZ RS15630
gene id: 545695:TREAZ_RS15630
uniprot id: F5YDU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

545695:TREAZ RS15580
gene id: 545695:TREAZ_RS15580
uniprot id: F5YDU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

545695:TREAZ RS09895
gene id: 545695:TREAZ_RS09895
uniprot id: F5YEA6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

545695:TREAZ RS01030
gene id: 545695:TREAZ_RS01030
uniprot id: F5Y9D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

545695:TREAZ RS11280
gene id: 545695:TREAZ_RS11280
uniprot id: F5Y6X1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

545695:TREAZ RS03690
gene id: 545695:TREAZ_RS03690
uniprot id: F5YE08
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

545695:TREAZ RS14590
gene id: 545695:TREAZ_RS14590
uniprot id: F5YCD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

545695:TREAZ RS16530
gene id: 545695:TREAZ_RS16530
uniprot id: F5YFP4
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

545695:TREAZ RS04670
gene id: 545695:TREAZ_RS04670
uniprot id: F5YFW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS16455
gene id: 545695:TREAZ_RS16455
uniprot id: F5YF71
names: Function
names: Similarity
messages: Belongs to the bacterial histone-like protein family.
messages: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.

545695:TREAZ RS02875
gene id: 545695:TREAZ_RS02875
uniprot id: F5YCM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

545695:TREAZ RS12080
gene id: 545695:TREAZ_RS12080
uniprot id: F5Y7U8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

545695:TREAZ RS04845
gene id: 545695:TREAZ_RS04845
uniprot id: F5YG04
names: Similarity
messages: Belongs to the aspartokinase family.

545695:TREAZ RS07370
gene id: 545695:TREAZ_RS07370
uniprot id: F5YA64
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

545695:TREAZ RS16945
gene id: 545695:TREAZ_RS16945
uniprot id: F5YGD4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

545695:TREAZ RS05000
gene id: 545695:TREAZ_RS05000
uniprot id: F5Y6K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

545695:TREAZ RS02310
gene id: 545695:TREAZ_RS02310
uniprot id: F5YBF9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

545695:TREAZ RS04550
gene id: 545695:TREAZ_RS04550
uniprot id: F5YFD8
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS10975
gene id: 545695:TREAZ_RS10975
uniprot id: F5YG88
names: Similarity
messages: Belongs to the TPP enzyme family.

545695:TREAZ RS05040
gene id: 545695:TREAZ_RS05040
uniprot id: F5Y6L0
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS03605
gene id: 545695:TREAZ_RS03605
uniprot id: F5YDZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

545695:TREAZ RS09560
gene id: 545695:TREAZ_RS09560
uniprot id: F5YDM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

545695:TREAZ RS07010
gene id: 545695:TREAZ_RS07010
uniprot id: F5Y9J2
names: Similarity
messages: Belongs to the UPF0164 family.

545695:TREAZ RS11030
gene id: 545695:TREAZ_RS11030
uniprot id: F5YG99
names: Similarity
messages: Belongs to the LacAB/RpiB family.

545695:TREAZ RS09410
gene id: 545695:TREAZ_RS09410
uniprot id: F5YDJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

545695:TREAZ RS13220
gene id: 545695:TREAZ_RS13220
uniprot id: F5Y9U0
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

545695:TREAZ RS09615
gene id: 545695:TREAZ_RS09615
uniprot id: F5YE44
names: Similarity
messages: Belongs to the DNase I family.

545695:TREAZ RS13675
gene id: 545695:TREAZ_RS13675
uniprot id: F5YAI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

545695:TREAZ RS15600
gene id: 545695:TREAZ_RS15600
uniprot id: F5YDU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

545695:TREAZ RS14610
gene id: 545695:TREAZ_RS14610
uniprot id: F5YCD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

545695:TREAZ RS10615
gene id: 545695:TREAZ_RS10615
uniprot id: F5YFK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

545695:TREAZ RS07340
gene id: 545695:TREAZ_RS07340
uniprot id: F5YA58
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

545695:TREAZ RS06645
gene id: 545695:TREAZ_RS06645
uniprot id: F5Y8W0
names: Similarity
messages: Belongs to the UPF0178 family.

545695:TREAZ RS12835
gene id: 545695:TREAZ_RS12835
uniprot id: F5Y960
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS04490
gene id: 545695:TREAZ_RS04490
uniprot id: F5YFC6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

545695:TREAZ RS16580
gene id: 545695:TREAZ_RS16580
uniprot id: F5YFQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

545695:TREAZ RS16245
gene id: 545695:TREAZ_RS16245
uniprot id: F5YF34
names: Similarity
messages: Belongs to the threonine synthase family.

545695:TREAZ RS11715
gene id: 545695:TREAZ_RS11715
uniprot id: F5Y7D5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

545695:TREAZ RS00500
gene id: 545695:TREAZ_RS00500
uniprot id: F5Y8M4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

545695:TREAZ RS16185
gene id: 545695:TREAZ_RS16185
uniprot id: F5YF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS02775
gene id: 545695:TREAZ_RS02775
uniprot id: F5YCK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS11535
gene id: 545695:TREAZ_RS11535
uniprot id: F5Y7A0
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

545695:TREAZ RS13960
gene id: 545695:TREAZ_RS13960
uniprot id: F5YB50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

545695:TREAZ RS01180
gene id: 545695:TREAZ_RS01180
uniprot id: F5Y9G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

545695:TREAZ RS12055
gene id: 545695:TREAZ_RS12055
uniprot id: F5Y7U3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

545695:TREAZ RS12415
gene id: 545695:TREAZ_RS12415
uniprot id: F5Y8H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

545695:TREAZ RS16575
gene id: 545695:TREAZ_RS16575
uniprot id: F5YFQ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

545695:TREAZ RS14145
gene id: 545695:TREAZ_RS14145
uniprot id: F5YB89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS15645
gene id: 545695:TREAZ_RS15645
uniprot id: F5YDV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

545695:TREAZ RS03365
gene id: 545695:TREAZ_RS03365
uniprot id: F5YDD8
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS04655
gene id: 545695:TREAZ_RS04655
uniprot id: F5YFW5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

545695:TREAZ RS12975
gene id: 545695:TREAZ_RS12975
uniprot id: F5Y989
names: Function
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

545695:TREAZ RS00470
gene id: 545695:TREAZ_RS00470
uniprot id: F5Y8L7
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS00945
gene id: 545695:TREAZ_RS00945
uniprot id: F5Y9C1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

545695:TREAZ RS10545
gene id: 545695:TREAZ_RS10545
uniprot id: F5YFJ4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

545695:TREAZ RS00605
gene id: 545695:TREAZ_RS00605
uniprot id: F5Y8P4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

545695:TREAZ RS11220
gene id: 545695:TREAZ_RS11220
uniprot id: F5Y6V8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

545695:TREAZ RS11240
gene id: 545695:TREAZ_RS11240
uniprot id: F5Y6W3
names: Similarity
messages: Belongs to the pyruvate kinase family.

545695:TREAZ RS02050
gene id: 545695:TREAZ_RS02050
uniprot id: F5YBA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

545695:TREAZ RS05250
gene id: 545695:TREAZ_RS05250
uniprot id: F5Y6Q1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

545695:TREAZ RS04740
gene id: 545695:TREAZ_RS04740
uniprot id: F5YFY4
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS10890
gene id: 545695:TREAZ_RS10890
uniprot id: F5YG71
names: Similarity
messages: Belongs to the UPF0175 family.

545695:TREAZ RS16110
gene id: 545695:TREAZ_RS16110
uniprot id: F5YF06
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

545695:TREAZ RS15585
gene id: 545695:TREAZ_RS15585
uniprot id: F5YDU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

545695:TREAZ RS07540
gene id: 545695:TREAZ_RS07540
uniprot id: F5YA98
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

545695:TREAZ RS12960
gene id: 545695:TREAZ_RS12960
uniprot id: F5Y986
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

545695:TREAZ RS04105
gene id: 545695:TREAZ_RS04105
uniprot id: F5YEQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

545695:TREAZ RS10395
gene id: 545695:TREAZ_RS10395
uniprot id: F5YFG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

545695:TREAZ RS05730
gene id: 545695:TREAZ_RS05730
uniprot id: F5Y776
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

545695:TREAZ RS03775
gene id: 545695:TREAZ_RS03775
uniprot id: F5YE23
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS00780
gene id: 545695:TREAZ_RS00780
uniprot id: F5Y8T1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

545695:TREAZ RS06580
gene id: 545695:TREAZ_RS06580
uniprot id: F5Y8U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

545695:TREAZ RS10220
gene id: 545695:TREAZ_RS10220
uniprot id: F5YEX3
names: Similarity
messages: Belongs to the DtxR/MntR family.

545695:TREAZ RS15875
gene id: 545695:TREAZ_RS15875
uniprot id: F5YEF6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

545695:TREAZ RS00025
gene id: 545695:TREAZ_RS00025
uniprot id: F5Y7G7
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

545695:TREAZ RS04610
gene id: 545695:TREAZ_RS04610
uniprot id: F5YFF0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

545695:TREAZ RS03185
gene id: 545695:TREAZ_RS03185
uniprot id: F5YDA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS16300
gene id: 545695:TREAZ_RS16300
uniprot id: F5YF44
names: Similarity
messages: Belongs to the peptidase S49 family.

545695:TREAZ RS03640
gene id: 545695:TREAZ_RS03640
uniprot id: F5YDZ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

545695:TREAZ RS10260
gene id: 545695:TREAZ_RS10260
uniprot id: F5YEY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

545695:TREAZ RS15635
gene id: 545695:TREAZ_RS15635
uniprot id: F5YDV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

545695:TREAZ RS00675
gene id: 545695:TREAZ_RS00675
uniprot id: F5Y8Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

545695:TREAZ RS04110
gene id: 545695:TREAZ_RS04110
uniprot id: F5YEQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

545695:TREAZ RS02105
gene id: 545695:TREAZ_RS02105
uniprot id: F5YBC0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

545695:TREAZ RS03495
gene id: 545695:TREAZ_RS03495
uniprot id: F5YDW9
names: Similarity
messages: Belongs to the glutamate synthase family.

545695:TREAZ RS09655
gene id: 545695:TREAZ_RS09655
uniprot id: F5YE53
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

545695:TREAZ RS04310
gene id: 545695:TREAZ_RS04310
uniprot id: F5YF90
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

545695:TREAZ RS08395
gene id: 545695:TREAZ_RS08395
uniprot id: F5YBM6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

545695:TREAZ RS04925
gene id: 545695:TREAZ_RS04925
uniprot id: F5YG18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

545695:TREAZ RS11365
gene id: 545695:TREAZ_RS11365
uniprot id: F5Y6Y7
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

545695:TREAZ RS08730
gene id: 545695:TREAZ_RS08730
uniprot id: F5YC94
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

545695:TREAZ RS04735
gene id: 545695:TREAZ_RS04735
uniprot id: F5YFY3
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS06895
gene id: 545695:TREAZ_RS06895
uniprot id: F5Y911
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

545695:TREAZ RS03330
gene id: 545695:TREAZ_RS03330
uniprot id: F5YDD2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

545695:TREAZ RS06685
gene id: 545695:TREAZ_RS06685
uniprot id: F5Y8W8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

545695:TREAZ RS14930
gene id: 545695:TREAZ_RS14930
uniprot id: F5YD08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

545695:TREAZ RS14820
gene id: 545695:TREAZ_RS14820
uniprot id: F5YCH7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

545695:TREAZ RS02370
gene id: 545695:TREAZ_RS02370
uniprot id: F5YBX1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

545695:TREAZ RS07480
gene id: 545695:TREAZ_RS07480
uniprot id: F5YA86
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

545695:TREAZ RS12795
gene id: 545695:TREAZ_RS12795
uniprot id: F5Y952
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

545695:TREAZ RS12890
gene id: 545695:TREAZ_RS12890
uniprot id: F5Y971
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

545695:TREAZ RS08945
gene id: 545695:TREAZ_RS08945
uniprot id: F5YCU5
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

545695:TREAZ RS12155
gene id: 545695:TREAZ_RS12155
uniprot id: F5Y7W4
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS15660
gene id: 545695:TREAZ_RS15660
uniprot id: F5YDV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

545695:TREAZ RS05295
gene id: 545695:TREAZ_RS05295
uniprot id: F5Y6R0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

545695:TREAZ RS00100
gene id: 545695:TREAZ_RS00100
uniprot id: F5Y7Y8
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS06660
gene id: 545695:TREAZ_RS06660
uniprot id: F5Y8W3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

545695:TREAZ RS10040
gene id: 545695:TREAZ_RS10040
uniprot id: F5YET7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

545695:TREAZ RS09420
gene id: 545695:TREAZ_RS09420
uniprot id: F5YDJ8
names: Function
names: Subcellular Location Annotation
messages: Component of the core of the flagella.
messages: Periplasmic flagellum

545695:TREAZ RS01590
gene id: 545695:TREAZ_RS01590
uniprot id: F5YA51
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

545695:TREAZ RS15640
gene id: 545695:TREAZ_RS15640
uniprot id: F5YDV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

545695:TREAZ RS08480
gene id: 545695:TREAZ_RS08480
uniprot id: F5YC40
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

545695:TREAZ RS17145
gene id: 545695:TREAZ_RS17145
uniprot id: F5YGH7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

545695:TREAZ RS04450
gene id: 545695:TREAZ_RS04450
uniprot id: F5YFB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

545695:TREAZ RS10635
gene id: 545695:TREAZ_RS10635
uniprot id: F5YFL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

545695:TREAZ RS04225
gene id: 545695:TREAZ_RS04225
uniprot id: F5YF74
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

545695:TREAZ RS12410
gene id: 545695:TREAZ_RS12410
uniprot id: F5Y8H2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

545695:TREAZ RS06595
gene id: 545695:TREAZ_RS06595
uniprot id: F5Y8V1
names: Subcellular Location Annotation
messages: Cell inner membrane

545695:TREAZ RS14850
gene id: 545695:TREAZ_RS14850
uniprot id: F5YCI3
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS15575
gene id: 545695:TREAZ_RS15575
uniprot id: F5YDT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

545695:TREAZ RS12530
gene id: 545695:TREAZ_RS12530
uniprot id: F5Y8J5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

545695:TREAZ RS14475
gene id: 545695:TREAZ_RS14475
uniprot id: F5YBV8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

545695:TREAZ RS00010
gene id: 545695:TREAZ_RS00010
uniprot id: F5Y7G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

545695:TREAZ RS10165
gene id: 545695:TREAZ_RS10165
uniprot id: F5YEW2
names: Similarity
messages: Belongs to the FlgD family.

545695:TREAZ RS15680
gene id: 545695:TREAZ_RS15680
uniprot id: F5YDV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

545695:TREAZ RS10710
gene id: 545695:TREAZ_RS10710
uniprot id: F5YG37
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

545695:TREAZ RS11460
gene id: 545695:TREAZ_RS11460
uniprot id: F5Y707
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS05515
gene id: 545695:TREAZ_RS05515
uniprot id: F5Y730
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

545695:TREAZ RS10425
gene id: 545695:TREAZ_RS10425
uniprot id: F5YFG7
names: Function
names: Similarity
messages: Belongs to the bacterial histone-like protein family.
messages: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.

545695:TREAZ RS06415
gene id: 545695:TREAZ_RS06415
uniprot id: F5Y8B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS12275
gene id: 545695:TREAZ_RS12275
uniprot id: F5Y8E2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

545695:TREAZ RS14295
gene id: 545695:TREAZ_RS14295
uniprot id: F5YBS3
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

545695:TREAZ RS17240
gene id: 545695:TREAZ_RS17240
uniprot id: F5YCR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

545695:TREAZ RS08905
gene id: 545695:TREAZ_RS08905
uniprot id: F5YCT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

545695:TREAZ RS02685
gene id: 545695:TREAZ_RS02685
uniprot id: F5YC30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

545695:TREAZ RS15760
gene id: 545695:TREAZ_RS15760
uniprot id: F5YED2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

545695:TREAZ RS05200
gene id: 545695:TREAZ_RS05200
uniprot id: F5Y6P1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

545695:TREAZ RS06590
gene id: 545695:TREAZ_RS06590
uniprot id: F5Y8V0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

545695:TREAZ RS03460
gene id: 545695:TREAZ_RS03460
uniprot id: F5YDW2
names: Similarity
messages: Belongs to the ParB family.

545695:TREAZ RS11300
gene id: 545695:TREAZ_RS11300
uniprot id: F5Y6X5
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

545695:TREAZ RS07500
gene id: 545695:TREAZ_RS07500
uniprot id: F5YA91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

545695:TREAZ RS08780
gene id: 545695:TREAZ_RS08780
uniprot id: F5YCA3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

545695:TREAZ RS04545
gene id: 545695:TREAZ_RS04545
uniprot id: F5YFD7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

545695:TREAZ RS09645
gene id: 545695:TREAZ_RS09645
uniprot id: F5YE51
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

545695:TREAZ RS08785
gene id: 545695:TREAZ_RS08785
uniprot id: F5YCA4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

545695:TREAZ RS11805
gene id: 545695:TREAZ_RS11805
uniprot id: F5Y7F3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

545695:TREAZ RS08300
gene id: 545695:TREAZ_RS08300
uniprot id: F5YBK5
names: Similarity
messages: Belongs to the RutC family.

545695:TREAZ RS16180
gene id: 545695:TREAZ_RS16180
uniprot id: F5YF21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS09805
gene id: 545695:TREAZ_RS09805
uniprot id: F5YE88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

545695:TREAZ RS07150
gene id: 545695:TREAZ_RS07150
uniprot id: F5Y9L7
names: Subcellular Location Annotation
messages: Membrane

545695:TREAZ RS08065
gene id: 545695:TREAZ_RS08065
uniprot id: F5YB07
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS05095
gene id: 545695:TREAZ_RS05095
uniprot id: F5Y6M1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

545695:TREAZ RS06735
gene id: 545695:TREAZ_RS06735
uniprot id: F5Y8X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

545695:TREAZ RS03935
gene id: 545695:TREAZ_RS03935
uniprot id: F5YEL4
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

545695:TREAZ RS04165
gene id: 545695:TREAZ_RS04165
uniprot id: F5YER4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

545695:TREAZ RS13920
gene id: 545695:TREAZ_RS13920
uniprot id: F5YB43
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS08595
gene id: 545695:TREAZ_RS08595
uniprot id: F5YC65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

545695:TREAZ RS03995
gene id: 545695:TREAZ_RS03995
uniprot id: F5YEM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS07655
gene id: 545695:TREAZ_RS07655
uniprot id: F5YAC3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

545695:TREAZ RS02180
gene id: 545695:TREAZ_RS02180
uniprot id: F5YBD5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

545695:TREAZ RS07700
gene id: 545695:TREAZ_RS07700
uniprot id: F5YAT4
names: Similarity
messages: Belongs to the Nth/MutY family.

545695:TREAZ RS00370
gene id: 545695:TREAZ_RS00370
uniprot id: F5Y842
names: Similarity
messages: Belongs to the CobT family.

545695:TREAZ RS14730
gene id: 545695:TREAZ_RS14730
uniprot id: F5YCF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

545695:TREAZ RS14770
gene id: 545695:TREAZ_RS14770
uniprot id: F5YCG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

545695:TREAZ RS09950
gene id: 545695:TREAZ_RS09950
uniprot id: F5YEB7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

545695:TREAZ RS04540
gene id: 545695:TREAZ_RS04540
uniprot id: F5YFD6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

545695:TREAZ RS06475
gene id: 545695:TREAZ_RS06475
uniprot id: F5Y8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

545695:TREAZ RS13450
gene id: 545695:TREAZ_RS13450
uniprot id: F5YAE0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

545695:TREAZ RS12400
gene id: 545695:TREAZ_RS12400
uniprot id: F5Y8H0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

545695:TREAZ RS14035
gene id: 545695:TREAZ_RS14035
uniprot id: F5YB67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

545695:TREAZ RS12210
gene id: 545695:TREAZ_RS12210
uniprot id: F5Y7X5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

545695:TREAZ RS06435
gene id: 545695:TREAZ_RS06435
uniprot id: F5Y8B4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

545695:TREAZ RS11115
gene id: 545695:TREAZ_RS11115
uniprot id: F5Y6T6
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

545695:TREAZ RS15890
gene id: 545695:TREAZ_RS15890
uniprot id: F5YEF9
names: Similarity
messages: Belongs to the hemerythrin family.

545695:TREAZ RS15845
gene id: 545695:TREAZ_RS15845
uniprot id: F5YEF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

545695:TREAZ RS13535
gene id: 545695:TREAZ_RS13535
uniprot id: F5YAF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane