543877:AM2010 RS02515
gene id: 543877:AM2010_RS02515
uniprot id: A0A0G3X7L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

543877:AM2010 RS05025
gene id: 543877:AM2010_RS05025
uniprot id: A0A0G3X8Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

543877:AM2010 RS11255
gene id: 543877:AM2010_RS11255
uniprot id: A0A0G3XAS1
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

543877:AM2010 RS07750
gene id: 543877:AM2010_RS07750
uniprot id: A0A0G3XAH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

543877:AM2010 RS00475
gene id: 543877:AM2010_RS00475
uniprot id: A0A0G3X6E0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

543877:AM2010 RS13570
gene id: 543877:AM2010_RS13570
uniprot id: A0A0G3XB30
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS09415
gene id: 543877:AM2010_RS09415
uniprot id: A0A0G3XBE0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

543877:AM2010 RS05135
gene id: 543877:AM2010_RS05135
uniprot id: A0A0G3X9S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

543877:AM2010 RS13130
gene id: 543877:AM2010_RS13130
uniprot id: A0A0G3XAV4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

543877:AM2010 RS04140
gene id: 543877:AM2010_RS04140
uniprot id: A0A0G3X921
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

543877:AM2010 RS11415
gene id: 543877:AM2010_RS11415
uniprot id: A0A0G3XD41
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

543877:AM2010 RS07545
gene id: 543877:AM2010_RS07545
uniprot id: A0A0G3XB38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

543877:AM2010 RS08085
gene id: 543877:AM2010_RS08085
uniprot id: A0A0G3XAP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

543877:AM2010 RS07880
gene id: 543877:AM2010_RS07880
uniprot id: A0A0G3XAK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS00425
gene id: 543877:AM2010_RS00425
uniprot id: A0A0G3X6D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

543877:AM2010 RS05915
gene id: 543877:AM2010_RS05915
uniprot id: A0A0G3X9F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

543877:AM2010 RS02035
gene id: 543877:AM2010_RS02035
uniprot id: A0A0G3X4I5
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

543877:AM2010 RS07550
gene id: 543877:AM2010_RS07550
uniprot id: A0A0G3XAE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

543877:AM2010 RS00495
gene id: 543877:AM2010_RS00495
uniprot id: A0A0G3X3U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

543877:AM2010 RS07520
gene id: 543877:AM2010_RS07520
uniprot id: A0A0G3XB33
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

543877:AM2010 RS07340
gene id: 543877:AM2010_RS07340
uniprot id: A0A0G3XAZ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

543877:AM2010 RS08825
gene id: 543877:AM2010_RS08825
uniprot id: A0A0G3X9D3
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS04720
gene id: 543877:AM2010_RS04720
uniprot id: A0A0G3X9E5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

543877:AM2010 RS03000
gene id: 543877:AM2010_RS03000
uniprot id: A0A0G3X594
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

543877:AM2010 RS08730
gene id: 543877:AM2010_RS08730
uniprot id: A0A0G3XB05
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

543877:AM2010 RS07275
gene id: 543877:AM2010_RS07275
uniprot id: A0A0G3X8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

543877:AM2010 RS01660
gene id: 543877:AM2010_RS01660
uniprot id: A0A0G3X712
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

543877:AM2010 RS01670
gene id: 543877:AM2010_RS01670
uniprot id: A0A0G3X7N9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

543877:AM2010 RS04590
gene id: 543877:AM2010_RS04590
uniprot id: A0A0G3X720
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS08055
gene id: 543877:AM2010_RS08055
uniprot id: A0A0G3XAN8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

543877:AM2010 RS12770
gene id: 543877:AM2010_RS12770
uniprot id: A0A0G3XAN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS09390
gene id: 543877:AM2010_RS09390
uniprot id: A0A0G3XBD5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

543877:AM2010 RS02540
gene id: 543877:AM2010_RS02540
uniprot id: A0A0G3X7M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

543877:AM2010 RS07475
gene id: 543877:AM2010_RS07475
uniprot id: A0A0G3XAD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

543877:AM2010 RS04540
gene id: 543877:AM2010_RS04540
uniprot id: A0A0G3X709
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

543877:AM2010 RS07910
gene id: 543877:AM2010_RS07910
uniprot id: A0A0G3X7X5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

543877:AM2010 RS02260
gene id: 543877:AM2010_RS02260
uniprot id: A0A0G3X7H6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

543877:AM2010 RS10120
gene id: 543877:AM2010_RS10120
uniprot id: A0A0G3XBS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS08060
gene id: 543877:AM2010_RS08060
uniprot id: A0A0G3X802
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

543877:AM2010 RS13055
gene id: 543877:AM2010_RS13055
uniprot id: A0A0G3XDE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

543877:AM2010 RS05360
gene id: 543877:AM2010_RS05360
uniprot id: A0A0G3X941
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

543877:AM2010 RS00945
gene id: 543877:AM2010_RS00945
uniprot id: A0A0G3X6P3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

543877:AM2010 RS05575
gene id: 543877:AM2010_RS05575
uniprot id: A0A0G3X7K7
names: Similarity
messages: Belongs to the GST superfamily.

543877:AM2010 RS00635
gene id: 543877:AM2010_RS00635
uniprot id: A0A0G3X6G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

543877:AM2010 RS07780
gene id: 543877:AM2010_RS07780
uniprot id: A0A0G3X7V2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

543877:AM2010 RS03745
gene id: 543877:AM2010_RS03745
uniprot id: A0A0G3X880
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

543877:AM2010 RS03740
gene id: 543877:AM2010_RS03740
uniprot id: A0A0G3X8V5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

543877:AM2010 RS04050
gene id: 543877:AM2010_RS04050
uniprot id: A0A0G3X8C5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS07590
gene id: 543877:AM2010_RS07590
uniprot id: A0A0G3X8S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

543877:AM2010 RS09160
gene id: 543877:AM2010_RS09160
uniprot id: A0A0G3XB87
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

543877:AM2010 RS03450
gene id: 543877:AM2010_RS03450
uniprot id: A0A0G3X5H5
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

543877:AM2010 RS13590
gene id: 543877:AM2010_RS13590
uniprot id: A0A0G3XDS5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

543877:AM2010 RS01965
gene id: 543877:AM2010_RS01965
uniprot id: A0A0G3X5L1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

543877:AM2010 RS09945
gene id: 543877:AM2010_RS09945
uniprot id: A0A0G3X934
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

543877:AM2010 RS05815
gene id: 543877:AM2010_RS05815
uniprot id: A0A0G3X9E2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS06650
gene id: 543877:AM2010_RS06650
uniprot id: A0A0G3XAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

543877:AM2010 RS02020
gene id: 543877:AM2010_RS02020
uniprot id: A0A0G3X7W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

543877:AM2010 RS05390
gene id: 543877:AM2010_RS05390
uniprot id: A0A0G3X947
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

543877:AM2010 RS09890
gene id: 543877:AM2010_RS09890
uniprot id: A0A0G3XBR8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS04655
gene id: 543877:AM2010_RS04655
uniprot id: A0A0G3X612
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

543877:AM2010 RS03835
gene id: 543877:AM2010_RS03835
uniprot id: A0A0G3X8X4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

543877:AM2010 RS00785
gene id: 543877:AM2010_RS00785
uniprot id: A0A0G3X3Y6
names: Similarity
messages: Belongs to the LOG family.

543877:AM2010 RS07510
gene id: 543877:AM2010_RS07510
uniprot id: A0A0G3XAC4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

543877:AM2010 RS05755
gene id: 543877:AM2010_RS05755
uniprot id: A0A0G3XA27
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

543877:AM2010 RS04370
gene id: 543877:AM2010_RS04370
uniprot id: A0A0G3X970
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

543877:AM2010 RS09040
gene id: 543877:AM2010_RS09040
uniprot id: A0A0G3X8H2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS13510
gene id: 543877:AM2010_RS13510
uniprot id: A0A0G3XEE4
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS14120
gene id: 543877:AM2010_RS14120
uniprot id: A0A0G3X750
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

543877:AM2010 RS12550
gene id: 543877:AM2010_RS12550
uniprot id: A0A0G3XBM1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

543877:AM2010 RS10575
gene id: 543877:AM2010_RS10575
uniprot id: A0A0G3XAD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

543877:AM2010 RS08190
gene id: 543877:AM2010_RS08190
uniprot id: A0A0G3X822
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

543877:AM2010 RS07095
gene id: 543877:AM2010_RS07095
uniprot id: A0A0G3X8F1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS11555
gene id: 543877:AM2010_RS11555
uniprot id: A0A0G3XCI3
names: Similarity
messages: Belongs to the cytochrome P450 family.

543877:AM2010 RS04210
gene id: 543877:AM2010_RS04210
uniprot id: A0A0G3X6U3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS11760
gene id: 543877:AM2010_RS11760
uniprot id: A0A0G3XCM7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543877:AM2010 RS08310
gene id: 543877:AM2010_RS08310
uniprot id: A0A0G3X939
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543877:AM2010 RS11275
gene id: 543877:AM2010_RS11275
uniprot id: A0A0G3XCC9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS05900
gene id: 543877:AM2010_RS05900
uniprot id: A0A0G3X9E4
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

543877:AM2010 RS12500
gene id: 543877:AM2010_RS12500
uniprot id: A0A0G3XBL3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

543877:AM2010 RS04105
gene id: 543877:AM2010_RS04105
uniprot id: A0A0G3X8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

543877:AM2010 RS10535
gene id: 543877:AM2010_RS10535
uniprot id: A0A0G3XC35
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543877:AM2010 RS00960
gene id: 543877:AM2010_RS00960
uniprot id: A0A0G3X523
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS11785
gene id: 543877:AM2010_RS11785
uniprot id: A0A0G3XCN1
names: Similarity
messages: Belongs to the UDPGP type 2 family.

543877:AM2010 RS10820
gene id: 543877:AM2010_RS10820
uniprot id: A0A0G3XC48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

543877:AM2010 RS04865
gene id: 543877:AM2010_RS04865
uniprot id: A0A0G3X7B9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

543877:AM2010 RS01155
gene id: 543877:AM2010_RS01155
uniprot id: A0A0G3X559
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS12505
gene id: 543877:AM2010_RS12505
uniprot id: A0A0G3XDW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS04335
gene id: 543877:AM2010_RS04335
uniprot id: A0A0G3X8I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

543877:AM2010 RS06270
gene id: 543877:AM2010_RS06270
uniprot id: A0A0G3XA95
names: Similarity
messages: Belongs to the histone deacetylase family.

543877:AM2010 RS07170
gene id: 543877:AM2010_RS07170
uniprot id: A0A0G3X8G8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

543877:AM2010 RS04990
gene id: 543877:AM2010_RS04990
uniprot id: A0A0G3X8Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

543877:AM2010 RS08990
gene id: 543877:AM2010_RS08990
uniprot id: A0A0G3X8G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

543877:AM2010 RS10990
gene id: 543877:AM2010_RS10990
uniprot id: A0A0G3X9L6
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

543877:AM2010 RS08040
gene id: 543877:AM2010_RS08040
uniprot id: A0A0G3XAL3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

543877:AM2010 RS13540
gene id: 543877:AM2010_RS13540
uniprot id: A0A0G3XDR7
names: Similarity
messages: Belongs to the Tim44 family.

543877:AM2010 RS11870
gene id: 543877:AM2010_RS11870
uniprot id: A0A0G3XA29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

543877:AM2010 RS02690
gene id: 543877:AM2010_RS02690
uniprot id: A0A0G3X7Q1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

543877:AM2010 RS04415
gene id: 543877:AM2010_RS04415
uniprot id: A0A0G3X6Y2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

543877:AM2010 RS12845
gene id: 543877:AM2010_RS12845
uniprot id: A0A0G3XAQ4
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.

543877:AM2010 RS06050
gene id: 543877:AM2010_RS06050
uniprot id: A0A0G3X6U2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

543877:AM2010 RS00095
gene id: 543877:AM2010_RS00095
uniprot id: A0A0G3X699
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

543877:AM2010 RS09185
gene id: 543877:AM2010_RS09185
uniprot id: A0A0G3XB92
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

543877:AM2010 RS10555
gene id: 543877:AM2010_RS10555
uniprot id: A0A0G3XCR2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

543877:AM2010 RS04115
gene id: 543877:AM2010_RS04115
uniprot id: A0A0G3X917
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

543877:AM2010 RS07240
gene id: 543877:AM2010_RS07240
uniprot id: A0A0G3XA38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

543877:AM2010 RS09610
gene id: 543877:AM2010_RS09610
uniprot id: A0A0G3XC27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

543877:AM2010 RS08245
gene id: 543877:AM2010_RS08245
uniprot id: A0A0G3XAS2
names: Similarity
messages: Belongs to the peptidase S8 family.

543877:AM2010 RS08945
gene id: 543877:AM2010_RS08945
uniprot id: A0A0G3X8F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

543877:AM2010 RS04215
gene id: 543877:AM2010_RS04215
uniprot id: A0A0G3X937
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

543877:AM2010 RS03180
gene id: 543877:AM2010_RS03180
uniprot id: A0A0G3X7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS07020
gene id: 543877:AM2010_RS07020
uniprot id: A0A0G3XA02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

543877:AM2010 RS02355
gene id: 543877:AM2010_RS02355
uniprot id: A0A0G3X889
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS08155
gene id: 543877:AM2010_RS08155
uniprot id: A0A0G3XBE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

543877:AM2010 RS03895
gene id: 543877:AM2010_RS03895
uniprot id: A0A0G3X8Y2
names: Similarity
messages: Belongs to the DEAD box helicase family.

543877:AM2010 RS01810
gene id: 543877:AM2010_RS01810
uniprot id: A0A0G3X760
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

543877:AM2010 RS07215
gene id: 543877:AM2010_RS07215
uniprot id: A0A0G3XA34
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

543877:AM2010 RS04130
gene id: 543877:AM2010_RS04130
uniprot id: A0A0G3X8E1
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

543877:AM2010 RS04885
gene id: 543877:AM2010_RS04885
uniprot id: A0A0G3X696
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

543877:AM2010 RS08490
gene id: 543877:AM2010_RS08490
uniprot id: A0A0G3X864
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS02845
gene id: 543877:AM2010_RS02845
uniprot id: A0A0G3X557
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS09930
gene id: 543877:AM2010_RS09930
uniprot id: A0A0G3XA45
names: Similarity
messages: Belongs to the ArsC family.

543877:AM2010 RS08625
gene id: 543877:AM2010_RS08625
uniprot id: A0A0G3XAW5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

543877:AM2010 RS03170
gene id: 543877:AM2010_RS03170
uniprot id: A0A0G3X7Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

543877:AM2010 RS03265
gene id: 543877:AM2010_RS03265
uniprot id: A0A0G3X6C4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

543877:AM2010 RS12635
gene id: 543877:AM2010_RS12635
uniprot id: A0A0G3XAL6
names: Similarity
messages: Belongs to the peptidase U62 family.

543877:AM2010 RS02100
gene id: 543877:AM2010_RS02100
uniprot id: A0A0G3X7Y4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

543877:AM2010 RS12315
gene id: 543877:AM2010_RS12315
uniprot id: A0A0G3XBD2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

543877:AM2010 RS11030
gene id: 543877:AM2010_RS11030
uniprot id: A0A0G3XAM4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

543877:AM2010 RS01050
gene id: 543877:AM2010_RS01050
uniprot id: A0A0G3X6P1
names: Similarity
messages: Belongs to the sulfatase family.

543877:AM2010 RS06975
gene id: 543877:AM2010_RS06975
uniprot id: A0A0G3X8C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

543877:AM2010 RS11975
gene id: 543877:AM2010_RS11975
uniprot id: A0A0G3XCS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

543877:AM2010 RS02500
gene id: 543877:AM2010_RS02500
uniprot id: A0A0G3X7J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

543877:AM2010 RS06730
gene id: 543877:AM2010_RS06730
uniprot id: A0A0G3X9W4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543877:AM2010 RS06555
gene id: 543877:AM2010_RS06555
uniprot id: A0A0G3XAE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

543877:AM2010 RS01800
gene id: 543877:AM2010_RS01800
uniprot id: A0A0G3X7R7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

543877:AM2010 RS06130
gene id: 543877:AM2010_RS06130
uniprot id: A0A0G3X9I1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

543877:AM2010 RS12805
gene id: 543877:AM2010_RS12805
uniprot id: A0A0G3XBQ0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

543877:AM2010 RS03070
gene id: 543877:AM2010_RS03070
uniprot id: A0A0G3X7X2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

543877:AM2010 RS05365
gene id: 543877:AM2010_RS05365
uniprot id: A0A0G3X7H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS01290
gene id: 543877:AM2010_RS01290
uniprot id: A0A0G3X482
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

543877:AM2010 RS00875
gene id: 543877:AM2010_RS00875
uniprot id: A0A0G3X402
names: Similarity
messages: Belongs to the Gfa family.

543877:AM2010 RS11335
gene id: 543877:AM2010_RS11335
uniprot id: A0A0G3XD32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

543877:AM2010 RS07705
gene id: 543877:AM2010_RS07705
uniprot id: A0A0G3X7T7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

543877:AM2010 RS13395
gene id: 543877:AM2010_RS13395
uniprot id: A0A0G3XAZ6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

543877:AM2010 RS07700
gene id: 543877:AM2010_RS07700
uniprot id: A0A0G3XAH1
names: Similarity
messages: Belongs to the ros/MucR family.

543877:AM2010 RS00725
gene id: 543877:AM2010_RS00725
uniprot id: A0A0G3X6K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

543877:AM2010 RS05775
gene id: 543877:AM2010_RS05775
uniprot id: A0A0G3X7P3
names: Similarity
messages: Belongs to the fabD family.

543877:AM2010 RS09495
gene id: 543877:AM2010_RS09495
uniprot id: A0A0G3X8Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS13200
gene id: 543877:AM2010_RS13200
uniprot id: A0A0G3XAW4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

543877:AM2010 RS05770
gene id: 543877:AM2010_RS05770
uniprot id: A0A0G3X9C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

543877:AM2010 RS11985
gene id: 543877:AM2010_RS11985
uniprot id: A0A0G3XDE8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

543877:AM2010 RS07115
gene id: 543877:AM2010_RS07115
uniprot id: A0A0G3XA18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

543877:AM2010 RS09770
gene id: 543877:AM2010_RS09770
uniprot id: A0A0G3XBK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

543877:AM2010 RS12570
gene id: 543877:AM2010_RS12570
uniprot id: A0A0G3XD63
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

543877:AM2010 RS00460
gene id: 543877:AM2010_RS00460
uniprot id: A0A0G3X751
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. In Gram-negative bacteria, at least four rings, L, P, S and M are present, whereas Gram-positive bacteria lack the L and P rings. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF build up the proximal portion of the rod with about 6 subunits each. Rod assembly occurs by export via the flagellum-specific pathway of its constituent proteins and by their incorporation into the rod structure in the probable order of FlgB, FlgC, FlgF and FlgG. Another protein, FliE, also assembles onto the stable rod structure.

543877:AM2010 RS10235
gene id: 543877:AM2010_RS10235
uniprot id: A0A0G3XBX2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

543877:AM2010 RS01815
gene id: 543877:AM2010_RS01815
uniprot id: A0A0G3X4F3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

543877:AM2010 RS10470
gene id: 543877:AM2010_RS10470
uniprot id: A0A0G3XAC0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

543877:AM2010 RS13500
gene id: 543877:AM2010_RS13500
uniprot id: A0A0G3XDN1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

543877:AM2010 RS04330
gene id: 543877:AM2010_RS04330
uniprot id: A0A0G3X5W7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

543877:AM2010 RS13305
gene id: 543877:AM2010_RS13305
uniprot id: A0A0G3XAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

543877:AM2010 RS13415
gene id: 543877:AM2010_RS13415
uniprot id: A0A0G3XDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

543877:AM2010 RS04550
gene id: 543877:AM2010_RS04550
uniprot id: A0A0G3X8M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

543877:AM2010 RS04670
gene id: 543877:AM2010_RS04670
uniprot id: A0A0G3X9D5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

543877:AM2010 RS06040
gene id: 543877:AM2010_RS06040
uniprot id: A0A0G3XA70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

543877:AM2010 RS11315
gene id: 543877:AM2010_RS11315
uniprot id: A0A0G3XCI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS00615
gene id: 543877:AM2010_RS00615
uniprot id: A0A0G3X4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS10845
gene id: 543877:AM2010_RS10845
uniprot id: A0A0G3XC53
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

543877:AM2010 RS08495
gene id: 543877:AM2010_RS08495
uniprot id: A0A0G3XAU3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543877:AM2010 RS08870
gene id: 543877:AM2010_RS08870
uniprot id: A0A0G3X8D8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

543877:AM2010 RS06465
gene id: 543877:AM2010_RS06465
uniprot id: A0A0G3X721
names: Similarity
messages: Belongs to the TrpC family.

543877:AM2010 RS09365
gene id: 543877:AM2010_RS09365
uniprot id: A0A0G3X8M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS02520
gene id: 543877:AM2010_RS02520
uniprot id: A0A0G3X4X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

543877:AM2010 RS01950
gene id: 543877:AM2010_RS01950
uniprot id: A0A0G3X786
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

543877:AM2010 RS09895
gene id: 543877:AM2010_RS09895
uniprot id: A0A0G3X924
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

543877:AM2010 RS04895
gene id: 543877:AM2010_RS04895
uniprot id: A0A0G3X7C2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

543877:AM2010 RS02430
gene id: 543877:AM2010_RS02430
uniprot id: A0A0G3X5X5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS01265
gene id: 543877:AM2010_RS01265
uniprot id: A0A0G3X479
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

543877:AM2010 RS03560
gene id: 543877:AM2010_RS03560
uniprot id: A0A0G3X5J7
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

543877:AM2010 RS04840
gene id: 543877:AM2010_RS04840
uniprot id: A0A0G3X7B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

543877:AM2010 RS02185
gene id: 543877:AM2010_RS02185
uniprot id: A0A0G3X4P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS06960
gene id: 543877:AM2010_RS06960
uniprot id: A0A0G3XA08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

543877:AM2010 RS05255
gene id: 543877:AM2010_RS05255
uniprot id: A0A0G3X922
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

543877:AM2010 RS05460
gene id: 543877:AM2010_RS05460
uniprot id: A0A0G3X971
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

543877:AM2010 RS12610
gene id: 543877:AM2010_RS12610
uniprot id: A0A0G3XAL2
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

543877:AM2010 RS02200
gene id: 543877:AM2010_RS02200
uniprot id: A0A0G3X863
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

543877:AM2010 RS06725
gene id: 543877:AM2010_RS06725
uniprot id: A0A0G3XAH3
names: Similarity
messages: Belongs to the asparagine synthetase family.

543877:AM2010 RS11715
gene id: 543877:AM2010_RS11715
uniprot id: A0A0G3XB02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

543877:AM2010 RS00300
gene id: 543877:AM2010_RS00300
uniprot id: A0A0G3X4Q1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

543877:AM2010 RS10005
gene id: 543877:AM2010_RS10005
uniprot id: A0A0G3XA56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

543877:AM2010 RS06330
gene id: 543877:AM2010_RS06330
uniprot id: A0A0G3X6Z7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

543877:AM2010 RS02470
gene id: 543877:AM2010_RS02470
uniprot id: A0A0G3X4W6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

543877:AM2010 RS06075
gene id: 543877:AM2010_RS06075
uniprot id: A0A0G3X6U6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

543877:AM2010 RS06810
gene id: 543877:AM2010_RS06810
uniprot id: A0A0G3X781
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS08295
gene id: 543877:AM2010_RS08295
uniprot id: A0A0G3XAT4
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS08090
gene id: 543877:AM2010_RS08090
uniprot id: A0A0G3X806
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS05425
gene id: 543877:AM2010_RS05425
uniprot id: A0A0G3X7I5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

543877:AM2010 RS12195
gene id: 543877:AM2010_RS12195
uniprot id: A0A0G3XCZ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS10915
gene id: 543877:AM2010_RS10915
uniprot id: A0A0G3X9K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

543877:AM2010 RS11290
gene id: 543877:AM2010_RS11290
uniprot id: A0A0G3XCH7
names: Similarity
messages: Belongs to the glutamate synthase family.

543877:AM2010 RS06645
gene id: 543877:AM2010_RS06645
uniprot id: A0A0G3X856
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

543877:AM2010 RS12665
gene id: 543877:AM2010_RS12665
uniprot id: A0A0G3XDB0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

543877:AM2010 RS00985
gene id: 543877:AM2010_RS00985
uniprot id: A0A0G3X528
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

543877:AM2010 RS06950
gene id: 543877:AM2010_RS06950
uniprot id: A0A0G3X8C1
names: Similarity
messages: Belongs to the AHA1 family.

543877:AM2010 RS03360
gene id: 543877:AM2010_RS03360
uniprot id: A0A0G3X5F9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

543877:AM2010 RS05160
gene id: 543877:AM2010_RS05160
uniprot id: A0A0G3X9S9
names: Similarity
messages: Belongs to the DprA/Smf family.

543877:AM2010 RS04595
gene id: 543877:AM2010_RS04595
uniprot id: A0A0G3X9B9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

543877:AM2010 RS07270
gene id: 543877:AM2010_RS07270
uniprot id: A0A0G3XA43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

543877:AM2010 RS05805
gene id: 543877:AM2010_RS05805
uniprot id: A0A0G3X7P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

543877:AM2010 RS06120
gene id: 543877:AM2010_RS06120
uniprot id: A0A0G3X9J4
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS03870
gene id: 543877:AM2010_RS03870
uniprot id: A0A0G3X8A6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

543877:AM2010 RS08330
gene id: 543877:AM2010_RS08330
uniprot id: A0A0G3XAR2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543877:AM2010 RS09615
gene id: 543877:AM2010_RS09615
uniprot id: A0A0G3XBH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

543877:AM2010 RS12545
gene id: 543877:AM2010_RS12545
uniprot id: A0A0G3XD61
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS02680
gene id: 543877:AM2010_RS02680
uniprot id: A0A0G3X604
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

543877:AM2010 RS02415
gene id: 543877:AM2010_RS02415
uniprot id: A0A0G3X7K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

543877:AM2010 RS00290
gene id: 543877:AM2010_RS00290
uniprot id: A0A0G3X3Q5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

543877:AM2010 RS11185
gene id: 543877:AM2010_RS11185
uniprot id: A0A0G3XD13
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

543877:AM2010 RS06940
gene id: 543877:AM2010_RS06940
uniprot id: A0A0G3X7A3
names: Similarity
messages: Belongs to the threonine synthase family.

543877:AM2010 RS02795
gene id: 543877:AM2010_RS02795
uniprot id: A0A0G3X7Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

543877:AM2010 RS00600
gene id: 543877:AM2010_RS00600
uniprot id: A0A0G3X6I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

543877:AM2010 RS10720
gene id: 543877:AM2010_RS10720
uniprot id: A0A0G3XC30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

543877:AM2010 RS08585
gene id: 543877:AM2010_RS08585
uniprot id: A0A0G3XAY0
names: Similarity
messages: Belongs to the peptidase M16 family.

543877:AM2010 RS08365
gene id: 543877:AM2010_RS08365
uniprot id: A0A0G3X949
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

543877:AM2010 RS04985
gene id: 543877:AM2010_RS04985
uniprot id: A0A0G3X6B2
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

543877:AM2010 RS01655
gene id: 543877:AM2010_RS01655
uniprot id: A0A0G3X4D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

543877:AM2010 RS10785
gene id: 543877:AM2010_RS10785
uniprot id: A0A0G3XC85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS03040
gene id: 543877:AM2010_RS03040
uniprot id: A0A0G3X8L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

543877:AM2010 RS13425
gene id: 543877:AM2010_RS13425
uniprot id: A0A0G3XDL7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

543877:AM2010 RS03690
gene id: 543877:AM2010_RS03690
uniprot id: A0A0G3X873
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

543877:AM2010 RS03785
gene id: 543877:AM2010_RS03785
uniprot id: A0A0G3X8W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

543877:AM2010 RS02380
gene id: 543877:AM2010_RS02380
uniprot id: A0A0G3X5W9
names: Similarity
messages: Belongs to the type IB topoisomerase family.

543877:AM2010 RS10220
gene id: 543877:AM2010_RS10220
uniprot id: A0A0G3XBU1
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS01905
gene id: 543877:AM2010_RS01905
uniprot id: A0A0G3X778
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS00285
gene id: 543877:AM2010_RS00285
uniprot id: A0A0G3X6C6
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS08035
gene id: 543877:AM2010_RS08035
uniprot id: A0A0G3X7Z7
names: Similarity
messages: Belongs to the BolA/IbaG family.

543877:AM2010 RS08105
gene id: 543877:AM2010_RS08105
uniprot id: A0A0G3XBD7
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

543877:AM2010 RS13350
gene id: 543877:AM2010_RS13350
uniprot id: A0A0G3XDK1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

543877:AM2010 RS03270
gene id: 543877:AM2010_RS03270
uniprot id: A0A0G3X8P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

543877:AM2010 RS03295
gene id: 543877:AM2010_RS03295
uniprot id: A0A0G3X8P8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS00555
gene id: 543877:AM2010_RS00555
uniprot id: A0A0G3X4W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

543877:AM2010 RS11080
gene id: 543877:AM2010_RS11080
uniprot id: A0A0G3XCZ9
names: Similarity
messages: Belongs to the peptidase S41A family.

543877:AM2010 RS10285
gene id: 543877:AM2010_RS10285
uniprot id: A0A0G3XBY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

543877:AM2010 RS07515
gene id: 543877:AM2010_RS07515
uniprot id: A0A0G3X8S1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

543877:AM2010 RS08740
gene id: 543877:AM2010_RS08740
uniprot id: A0A0G3XAY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

543877:AM2010 RS07110
gene id: 543877:AM2010_RS07110
uniprot id: A0A0G3X7C7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

543877:AM2010 RS10615
gene id: 543877:AM2010_RS10615
uniprot id: A0A0G3XC10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

543877:AM2010 RS07250
gene id: 543877:AM2010_RS07250
uniprot id: A0A0G3XAT5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

543877:AM2010 RS06015
gene id: 543877:AM2010_RS06015
uniprot id: A0A0G3XA67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

543877:AM2010 RS10910
gene id: 543877:AM2010_RS10910
uniprot id: A0A0G3XCA7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

543877:AM2010 RS04535
gene id: 543877:AM2010_RS04535
uniprot id: A0A0G3X8L8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

543877:AM2010 RS00805
gene id: 543877:AM2010_RS00805
uniprot id: A0A0G3X6L8
names: Similarity
messages: Belongs to the MipA/OmpV family.

543877:AM2010 RS01325
gene id: 543877:AM2010_RS01325
uniprot id: A0A0G3X6U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

543877:AM2010 RS13030
gene id: 543877:AM2010_RS13030
uniprot id: A0A0G3XDD9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

543877:AM2010 RS01350
gene id: 543877:AM2010_RS01350
uniprot id: A0A0G3X6V1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

543877:AM2010 RS08905
gene id: 543877:AM2010_RS08905
uniprot id: A0A0G3X9E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS09920
gene id: 543877:AM2010_RS09920
uniprot id: A0A0G3X929
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

543877:AM2010 RS05695
gene id: 543877:AM2010_RS05695
uniprot id: A0A0G3X7M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

543877:AM2010 RS11745
gene id: 543877:AM2010_RS11745
uniprot id: A0A0G3XD97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

543877:AM2010 RS03985
gene id: 543877:AM2010_RS03985
uniprot id: A0A0G3X8B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

543877:AM2010 RS03430
gene id: 543877:AM2010_RS03430
uniprot id: A0A0G3X818
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

543877:AM2010 RS08720
gene id: 543877:AM2010_RS08720
uniprot id: A0A0G3X9B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

543877:AM2010 RS02215
gene id: 543877:AM2010_RS02215
uniprot id: A0A0G3X7F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

543877:AM2010 RS02205
gene id: 543877:AM2010_RS02205
uniprot id: A0A0G3X7G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

543877:AM2010 RS12380
gene id: 543877:AM2010_RS12380
uniprot id: A0A0G3XAB3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

543877:AM2010 RS12210
gene id: 543877:AM2010_RS12210
uniprot id: A0A0G3XBB1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS07670
gene id: 543877:AM2010_RS07670
uniprot id: A0A0G3XB63
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

543877:AM2010 RS02940
gene id: 543877:AM2010_RS02940
uniprot id: A0A0G3X7U8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

543877:AM2010 RS00280
gene id: 543877:AM2010_RS00280
uniprot id: A0A0G3X718
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

543877:AM2010 RS04580
gene id: 543877:AM2010_RS04580
uniprot id: A0A0G3X5Z9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

543877:AM2010 RS08235
gene id: 543877:AM2010_RS08235
uniprot id: A0A0G3X923
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543877:AM2010 RS02245
gene id: 543877:AM2010_RS02245
uniprot id: A0A0G3X7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

543877:AM2010 RS07015
gene id: 543877:AM2010_RS07015
uniprot id: A0A0G3X7B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

543877:AM2010 RS13355
gene id: 543877:AM2010_RS13355
uniprot id: A0A0G3XBZ4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

543877:AM2010 RS05165
gene id: 543877:AM2010_RS05165
uniprot id: A0A0G3X916
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

543877:AM2010 RS04850
gene id: 543877:AM2010_RS04850
uniprot id: A0A0G3X8W9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

543877:AM2010 RS05835
gene id: 543877:AM2010_RS05835
uniprot id: A0A0G3XA39
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

543877:AM2010 RS05765
gene id: 543877:AM2010_RS05765
uniprot id: A0A0G3X6P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

543877:AM2010 RS08930
gene id: 543877:AM2010_RS08930
uniprot id: A0A0G3X9F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

543877:AM2010 RS12890
gene id: 543877:AM2010_RS12890
uniprot id: A0A0G3XDF0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543877:AM2010 RS08005
gene id: 543877:AM2010_RS08005
uniprot id: A0A0G3XAM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

543877:AM2010 RS11930
gene id: 543877:AM2010_RS11930
uniprot id: A0A0G3XB50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS00485
gene id: 543877:AM2010_RS00485
uniprot id: A0A0G3X755
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

543877:AM2010 RS12885
gene id: 543877:AM2010_RS12885
uniprot id: A0A0G3XE35
names: Similarity
messages: Belongs to the HIBADH-related family.

543877:AM2010 RS11450
gene id: 543877:AM2010_RS11450
uniprot id: A0A0G3X9V3
names: Similarity
messages: Belongs to the HesB/IscA family.

543877:AM2010 RS13490
gene id: 543877:AM2010_RS13490
uniprot id: A0A0G3XDQ9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

543877:AM2010 RS11600
gene id: 543877:AM2010_RS11600
uniprot id: A0A0G3XCN3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

543877:AM2010 RS08485
gene id: 543877:AM2010_RS08485
uniprot id: A0A0G3XAW3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543877:AM2010 RS12865
gene id: 543877:AM2010_RS12865
uniprot id: A0A0G3XDE6
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

543877:AM2010 RS09500
gene id: 543877:AM2010_RS09500
uniprot id: A0A0G3XBC3
names: Similarity
messages: Belongs to the ArsC family.

543877:AM2010 RS10000
gene id: 543877:AM2010_RS10000
uniprot id: A0A0G3XBQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

543877:AM2010 RS10875
gene id: 543877:AM2010_RS10875
uniprot id: A0A0G3XAI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

543877:AM2010 RS02030
gene id: 543877:AM2010_RS02030
uniprot id: A0A0G3X798
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS08175
gene id: 543877:AM2010_RS08175
uniprot id: A0A0G3X915
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

543877:AM2010 RS01000
gene id: 543877:AM2010_RS01000
uniprot id: A0A0G3X425
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

543877:AM2010 RS02170
gene id: 543877:AM2010_RS02170
uniprot id: A0A0G3X5U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS08535
gene id: 543877:AM2010_RS08535
uniprot id: A0A0G3X6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

543877:AM2010 RS06440
gene id: 543877:AM2010_RS06440
uniprot id: A0A0G3X9N7
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

543877:AM2010 RS11090
gene id: 543877:AM2010_RS11090
uniprot id: A0A0G3X9N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

543877:AM2010 RS09790
gene id: 543877:AM2010_RS09790
uniprot id: A0A0G3XC66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

543877:AM2010 RS09515
gene id: 543877:AM2010_RS09515
uniprot id: A0A0G3XBF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS11500
gene id: 543877:AM2010_RS11500
uniprot id: A0A0G3X9W0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

543877:AM2010 RS07060
gene id: 543877:AM2010_RS07060
uniprot id: A0A0G3X7C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

543877:AM2010 RS05150
gene id: 543877:AM2010_RS05150
uniprot id: A0A0G3X906
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

543877:AM2010 RS08665
gene id: 543877:AM2010_RS08665
uniprot id: A0A0G3XAZ1
names: Subunit
messages: Homodimer.

543877:AM2010 RS13340
gene id: 543877:AM2010_RS13340
uniprot id: A0A0G3XDN5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

543877:AM2010 RS06575
gene id: 543877:AM2010_RS06575
uniprot id: A0A0G3X841
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

543877:AM2010 RS03585
gene id: 543877:AM2010_RS03585
uniprot id: A0A0G3X5K3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

543877:AM2010 RS01095
gene id: 543877:AM2010_RS01095
uniprot id: A0A0G3X445
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

543877:AM2010 RS07920
gene id: 543877:AM2010_RS07920
uniprot id: A0A0G3X8X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

543877:AM2010 RS02070
gene id: 543877:AM2010_RS02070
uniprot id: A0A0G3X5N2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

543877:AM2010 RS04110
gene id: 543877:AM2010_RS04110
uniprot id: A0A0G3X6S0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

543877:AM2010 RS06475
gene id: 543877:AM2010_RS06475
uniprot id: A0A0G3X824
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

543877:AM2010 RS10850
gene id: 543877:AM2010_RS10850
uniprot id: A0A0G3XAI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

543877:AM2010 RS09875
gene id: 543877:AM2010_RS09875
uniprot id: A0A0G3XBJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS12530
gene id: 543877:AM2010_RS12530
uniprot id: A0A0G3XDW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

543877:AM2010 RS06160
gene id: 543877:AM2010_RS06160
uniprot id: A0A0G3X7X1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS10965
gene id: 543877:AM2010_RS10965
uniprot id: A0A0G3X9L1
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS06685
gene id: 543877:AM2010_RS06685
uniprot id: A0A0G3X762
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

543877:AM2010 RS06420
gene id: 543877:AM2010_RS06420
uniprot id: A0A0G3X816
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

543877:AM2010 RS04740
gene id: 543877:AM2010_RS04740
uniprot id: A0A0G3X752
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

543877:AM2010 RS01640
gene id: 543877:AM2010_RS01640
uniprot id: A0A0G3X5D8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

543877:AM2010 RS09075
gene id: 543877:AM2010_RS09075
uniprot id: A0A0G3X9H8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

543877:AM2010 RS02580
gene id: 543877:AM2010_RS02580
uniprot id: A0A0G3X5Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

543877:AM2010 RS08325
gene id: 543877:AM2010_RS08325
uniprot id: A0A0G3X838
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS09220
gene id: 543877:AM2010_RS09220
uniprot id: A0A0G3X9K2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

543877:AM2010 RS11330
gene id: 543877:AM2010_RS11330
uniprot id: A0A0G3XAT6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS09780
gene id: 543877:AM2010_RS09780
uniprot id: A0A0G3XBH4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

543877:AM2010 RS10195
gene id: 543877:AM2010_RS10195
uniprot id: A0A0G3XBT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS05100
gene id: 543877:AM2010_RS05100
uniprot id: A0A0G3X8Z8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

543877:AM2010 RS05315
gene id: 543877:AM2010_RS05315
uniprot id: A0A0G3X9V8
names: Similarity
messages: Belongs to the transketolase family.

543877:AM2010 RS06580
gene id: 543877:AM2010_RS06580
uniprot id: A0A0G3XAE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

543877:AM2010 RS03725
gene id: 543877:AM2010_RS03725
uniprot id: A0A0G3X865
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

543877:AM2010 RS12225
gene id: 543877:AM2010_RS12225
uniprot id: A0A0G3XA87
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543877:AM2010 RS07345
gene id: 543877:AM2010_RS07345
uniprot id: A0A0G3XAB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

543877:AM2010 RS01975
gene id: 543877:AM2010_RS01975
uniprot id: A0A0G3X790
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

543877:AM2010 RS05700
gene id: 543877:AM2010_RS05700
uniprot id: A0A0G3XA19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

543877:AM2010 RS06690
gene id: 543877:AM2010_RS06690
uniprot id: A0A0G3X9T6
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

543877:AM2010 RS03200
gene id: 543877:AM2010_RS03200
uniprot id: A0A0G3X7Z8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

543877:AM2010 RS06805
gene id: 543877:AM2010_RS06805
uniprot id: A0A0G3X9Y1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

543877:AM2010 RS04060
gene id: 543877:AM2010_RS04060
uniprot id: A0A0G3X908
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

543877:AM2010 RS02250
gene id: 543877:AM2010_RS02250
uniprot id: A0A0G3X5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

543877:AM2010 RS13595
gene id: 543877:AM2010_RS13595
uniprot id: A0A0G3XB36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

543877:AM2010 RS05475
gene id: 543877:AM2010_RS05475
uniprot id: A0A0G3X7J3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

543877:AM2010 RS10885
gene id: 543877:AM2010_RS10885
uniprot id: A0A0G3XCA3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

543877:AM2010 RS01015
gene id: 543877:AM2010_RS01015
uniprot id: A0A0G3X7D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

543877:AM2010 RS04420
gene id: 543877:AM2010_RS04420
uniprot id: A0A0G3X982
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS08110
gene id: 543877:AM2010_RS08110
uniprot id: A0A0G3XAP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

543877:AM2010 RS01110
gene id: 543877:AM2010_RS01110
uniprot id: A0A0G3X7E2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

543877:AM2010 RS09950
gene id: 543877:AM2010_RS09950
uniprot id: A0A0G3XBP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

543877:AM2010 RS01825
gene id: 543877:AM2010_RS01825
uniprot id: A0A0G3X5H6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

543877:AM2010 RS07145
gene id: 543877:AM2010_RS07145
uniprot id: A0A0G3X8G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

543877:AM2010 RS05780
gene id: 543877:AM2010_RS05780
uniprot id: A0A0G3XA31
names: Similarity
messages: Belongs to the peptidase S66 family.

543877:AM2010 RS02780
gene id: 543877:AM2010_RS02780
uniprot id: A0A0G3X8H0
names: Similarity
messages: Belongs to the CFA/CMAS family.

543877:AM2010 RS00440
gene id: 543877:AM2010_RS00440
uniprot id: A0A0G3X6F5
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

543877:AM2010 RS10275
gene id: 543877:AM2010_RS10275
uniprot id: A0A0G3XA91
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

543877:AM2010 RS06910
gene id: 543877:AM2010_RS06910
uniprot id: A0A0G3XA01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

543877:AM2010 RS01395
gene id: 543877:AM2010_RS01395
uniprot id: A0A0G3X499
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

543877:AM2010 RS13170
gene id: 543877:AM2010_RS13170
uniprot id: A0A0G3XE87
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

543877:AM2010 RS04870
gene id: 543877:AM2010_RS04870
uniprot id: A0A0G3X9M7
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS10715
gene id: 543877:AM2010_RS10715
uniprot id: A0A0G3X9H4
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

543877:AM2010 RS13035
gene id: 543877:AM2010_RS13035
uniprot id: A0A0G3XBT7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

543877:AM2010 RS04600
gene id: 543877:AM2010_RS04600
uniprot id: A0A0G3X8N7
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS10115
gene id: 543877:AM2010_RS10115
uniprot id: A0A0G3X967
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS00480
gene id: 543877:AM2010_RS00480
uniprot id: A0A0G3X4U5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

543877:AM2010 RS02650
gene id: 543877:AM2010_RS02650
uniprot id: A0A0G3X7M5
names: Similarity
messages: Belongs to the peptidase S9A family.

543877:AM2010 RS00970
gene id: 543877:AM2010_RS00970
uniprot id: A0A0G3X6P7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS04920
gene id: 543877:AM2010_RS04920
uniprot id: A0A0G3X7C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

543877:AM2010 RS04585
gene id: 543877:AM2010_RS04585
uniprot id: A0A0G3X8M7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

543877:AM2010 RS05745
gene id: 543877:AM2010_RS05745
uniprot id: A0A0G3X6N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

543877:AM2010 RS03470
gene id: 543877:AM2010_RS03470
uniprot id: A0A0G3X8S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

543877:AM2010 RS05175
gene id: 543877:AM2010_RS05175
uniprot id: A0A0G3X910
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

543877:AM2010 RS07135
gene id: 543877:AM2010_RS07135
uniprot id: A0A0G3X7D1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

543877:AM2010 RS06150
gene id: 543877:AM2010_RS06150
uniprot id: A0A0G3X6W0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

543877:AM2010 RS12720
gene id: 543877:AM2010_RS12720
uniprot id: A0A0G3XAN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS02960
gene id: 543877:AM2010_RS02960
uniprot id: A0A0G3X8K1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

543877:AM2010 RS13005
gene id: 543877:AM2010_RS13005
uniprot id: A0A0G3XDD4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543877:AM2010 RS13410
gene id: 543877:AM2010_RS13410
uniprot id: A0A0G3XEC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

543877:AM2010 RS13275
gene id: 543877:AM2010_RS13275
uniprot id: A0A0G3XDM2
names: Similarity
messages: Belongs to the peptidase M13 family.

543877:AM2010 RS11375
gene id: 543877:AM2010_RS11375
uniprot id: A0A0G3X9T9
names: Similarity
messages: Belongs to the HesB/IscA family.

543877:AM2010 RS05580
gene id: 543877:AM2010_RS05580
uniprot id: A0A0G3XA00
names: Similarity
messages: Belongs to the Gfa family.

543877:AM2010 RS12785
gene id: 543877:AM2010_RS12785
uniprot id: A0A0G3XE16
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

543877:AM2010 RS12095
gene id: 543877:AM2010_RS12095
uniprot id: A0A0G3XCX7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

543877:AM2010 RS08590
gene id: 543877:AM2010_RS08590
uniprot id: A0A0G3X887
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS08705
gene id: 543877:AM2010_RS08705
uniprot id: A0A0G3XB01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

543877:AM2010 RS12975
gene id: 543877:AM2010_RS12975
uniprot id: A0A0G3XAS7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

543877:AM2010 RS05880
gene id: 543877:AM2010_RS05880
uniprot id: A0A0G3X7R4
names: Similarity
messages: Belongs to the peptidase C56 family.

543877:AM2010 RS11310
gene id: 543877:AM2010_RS11310
uniprot id: A0A0G3XD29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

543877:AM2010 RS08960
gene id: 543877:AM2010_RS08960
uniprot id: A0A0G3XBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

543877:AM2010 RS04530
gene id: 543877:AM2010_RS04530
uniprot id: A0A0G3X5Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

543877:AM2010 RS08690
gene id: 543877:AM2010_RS08690
uniprot id: A0A0G3X8A7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

543877:AM2010 RS09705
gene id: 543877:AM2010_RS09705
uniprot id: A0A0G3XBG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

543877:AM2010 RS11425
gene id: 543877:AM2010_RS11425
uniprot id: A0A0G3X9U7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

543877:AM2010 RS03340
gene id: 543877:AM2010_RS03340
uniprot id: A0A0G3X804
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

543877:AM2010 RS04430
gene id: 543877:AM2010_RS04430
uniprot id: A0A0G3X5X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

543877:AM2010 RS08560
gene id: 543877:AM2010_RS08560
uniprot id: A0A0G3XAX5
names: Similarity
messages: Belongs to the pirin family.

543877:AM2010 RS13405
gene id: 543877:AM2010_RS13405
uniprot id: A0A0G3XC04
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

543877:AM2010 RS10145
gene id: 543877:AM2010_RS10145
uniprot id: A0A0G3XBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

543877:AM2010 RS06595
gene id: 543877:AM2010_RS06595
uniprot id: A0A0G3X9R6
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

543877:AM2010 RS10130
gene id: 543877:AM2010_RS10130
uniprot id: A0A0G3XCI4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

543877:AM2010 RS00680
gene id: 543877:AM2010_RS00680
uniprot id: A0A0G3X3X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

543877:AM2010 RS13810
gene id: 543877:AM2010_RS13810
uniprot id: A0A0G3X9V7
names: Similarity
messages: Belongs to the type III secretion exporter family.

543877:AM2010 RS01400
gene id: 543877:AM2010_RS01400
uniprot id: A0A0G3X6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

543877:AM2010 RS13525
gene id: 543877:AM2010_RS13525
uniprot id: A0A0G3XDN4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

543877:AM2010 RS06835
gene id: 543877:AM2010_RS06835
uniprot id: A0A0G3X785
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

543877:AM2010 RS10180
gene id: 543877:AM2010_RS10180
uniprot id: A0A0G3XCJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS13770
gene id: 543877:AM2010_RS13770
uniprot id: A0A0G3XAG2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

543877:AM2010 RS10210
gene id: 543877:AM2010_RS10210
uniprot id: A0A0G3XBW6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

543877:AM2010 RS01855
gene id: 543877:AM2010_RS01855
uniprot id: A0A0G3X768
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

543877:AM2010 RS09340
gene id: 543877:AM2010_RS09340
uniprot id: A0A0G3X8M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS04525
gene id: 543877:AM2010_RS04525
uniprot id: A0A0G3X8M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

543877:AM2010 RS10135
gene id: 543877:AM2010_RS10135
uniprot id: A0A0G3XBV4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

543877:AM2010 RS06610
gene id: 543877:AM2010_RS06610
uniprot id: A0A0G3X749
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

543877:AM2010 RS06115
gene id: 543877:AM2010_RS06115
uniprot id: A0A0G3XA78
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

543877:AM2010 RS03035
gene id: 543877:AM2010_RS03035
uniprot id: A0A0G3X651
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

543877:AM2010 RS02210
gene id: 543877:AM2010_RS02210
uniprot id: A0A0G3X4Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

543877:AM2010 RS02365
gene id: 543877:AM2010_RS02365
uniprot id: A0A0G3X4U7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

543877:AM2010 RS10090
gene id: 543877:AM2010_RS10090
uniprot id: A0A0G3X962
names: Similarity
messages: Belongs to the AAA ATPase family.

543877:AM2010 RS08920
gene id: 543877:AM2010_RS08920
uniprot id: A0A0G3X8E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

543877:AM2010 RS05280
gene id: 543877:AM2010_RS05280
uniprot id: A0A0G3X927
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS02665
gene id: 543877:AM2010_RS02665
uniprot id: A0A0G3X7P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

543877:AM2010 RS02160
gene id: 543877:AM2010_RS02160
uniprot id: A0A0G3X4P3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS06900
gene id: 543877:AM2010_RS06900
uniprot id: A0A0G3X8A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

543877:AM2010 RS00465
gene id: 543877:AM2010_RS00465
uniprot id: A0A0G3X6G0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

543877:AM2010 RS00205
gene id: 543877:AM2010_RS00205
uniprot id: A0A0G3X705
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

543877:AM2010 RS04395
gene id: 543877:AM2010_RS04395
uniprot id: A0A0G3X977
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS05305
gene id: 543877:AM2010_RS05305
uniprot id: A0A0G3X931
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

543877:AM2010 RS12465
gene id: 543877:AM2010_RS12465
uniprot id: A0A0G3XD49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

543877:AM2010 RS04010
gene id: 543877:AM2010_RS04010
uniprot id: A0A0G3X8C8
names: Similarity
messages: Belongs to the RecJ family.

543877:AM2010 RS10545
gene id: 543877:AM2010_RS10545
uniprot id: A0A0G3XBZ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

543877:AM2010 RS09430
gene id: 543877:AM2010_RS09430
uniprot id: A0A0G3X9P6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS02535
gene id: 543877:AM2010_RS02535
uniprot id: A0A0G3X8C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

543877:AM2010 RS01820
gene id: 543877:AM2010_RS01820
uniprot id: A0A0G3X743
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

543877:AM2010 RS06245
gene id: 543877:AM2010_RS06245
uniprot id: A0A0G3X9L8
names: Similarity
messages: Belongs to the asparaginase 1 family.

543877:AM2010 RS07725
gene id: 543877:AM2010_RS07725
uniprot id: A0A0G3XAH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

543877:AM2010 RS07150
gene id: 543877:AM2010_RS07150
uniprot id: A0A0G3XAR5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

543877:AM2010 RS03580
gene id: 543877:AM2010_RS03580
uniprot id: A0A0G3X852
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

543877:AM2010 RS05230
gene id: 543877:AM2010_RS05230
uniprot id: A0A0G3X918
names: Cofactor
messages: Can also use Mn(2+) ion.

543877:AM2010 RS09305
gene id: 543877:AM2010_RS09305
uniprot id: A0A0G3XBB9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

543877:AM2010 RS09740
gene id: 543877:AM2010_RS09740
uniprot id: A0A0G3XC56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS04360
gene id: 543877:AM2010_RS04360
uniprot id: A0A0G3X8I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

543877:AM2010 RS11835
gene id: 543877:AM2010_RS11835
uniprot id: A0A0G3XB28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS04965
gene id: 543877:AM2010_RS04965
uniprot id: A0A0G3X8Y1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

543877:AM2010 RS03140
gene id: 543877:AM2010_RS03140
uniprot id: A0A0G3X8M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

543877:AM2010 RS05435
gene id: 543877:AM2010_RS05435
uniprot id: A0A0G3X966
names: Similarity
messages: Belongs to the thioredoxin family.

543877:AM2010 RS09130
gene id: 543877:AM2010_RS09130
uniprot id: A0A0G3X9I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

543877:AM2010 RS03695
gene id: 543877:AM2010_RS03695
uniprot id: A0A0G3X5M0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

543877:AM2010 RS04675
gene id: 543877:AM2010_RS04675
uniprot id: A0A0G3X8Q2
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

543877:AM2010 RS02090
gene id: 543877:AM2010_RS02090
uniprot id: A0A0G3X789
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

543877:AM2010 RS02585
gene id: 543877:AM2010_RS02585
uniprot id: A0A0G3X8D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

543877:AM2010 RS03165
gene id: 543877:AM2010_RS03165
uniprot id: A0A0G3X8N0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

543877:AM2010 RS00650
gene id: 543877:AM2010_RS00650
uniprot id: A0A0G3X6J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

543877:AM2010 RS06895
gene id: 543877:AM2010_RS06895
uniprot id: A0A0G3X9X6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

543877:AM2010 RS13600
gene id: 543877:AM2010_RS13600
uniprot id: A0A0G3XDP5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

543877:AM2010 RS04070
gene id: 543877:AM2010_RS04070
uniprot id: A0A0G3X5T3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

543877:AM2010 RS02560
gene id: 543877:AM2010_RS02560
uniprot id: A0A0G3X8C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

543877:AM2010 RS06615
gene id: 543877:AM2010_RS06615
uniprot id: A0A0G3X9S1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

543877:AM2010 RS11685
gene id: 543877:AM2010_RS11685
uniprot id: A0A0G3XCL2
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

543877:AM2010 RS02635
gene id: 543877:AM2010_RS02635
uniprot id: A0A0G3X8E0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

543877:AM2010 RS01240
gene id: 543877:AM2010_RS01240
uniprot id: A0A0G3X474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

543877:AM2010 RS07745
gene id: 543877:AM2010_RS07745
uniprot id: A0A0G3XB78
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

543877:AM2010 RS02435
gene id: 543877:AM2010_RS02435
uniprot id: A0A0G3X8A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

543877:AM2010 RS07645
gene id: 543877:AM2010_RS07645
uniprot id: A0A0G3XB58
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

543877:AM2010 RS03150
gene id: 543877:AM2010_RS03150
uniprot id: A0A0G3X5B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

543877:AM2010 RS10540
gene id: 543877:AM2010_RS10540
uniprot id: A0A0G3X9E6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

543877:AM2010 RS09720
gene id: 543877:AM2010_RS09720
uniprot id: A0A0G3XBJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

543877:AM2010 RS04170
gene id: 543877:AM2010_RS04170
uniprot id: A0A0G3X8F9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

543877:AM2010 RS07685
gene id: 543877:AM2010_RS07685
uniprot id: A0A0G3XAF0
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

543877:AM2010 RS06105
gene id: 543877:AM2010_RS06105
uniprot id: A0A0G3X9H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

543877:AM2010 RS01625
gene id: 543877:AM2010_RS01625
uniprot id: A0A0G3X724
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

543877:AM2010 RS11050
gene id: 543877:AM2010_RS11050
uniprot id: A0A0G3XAM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

543877:AM2010 RS09840
gene id: 543877:AM2010_RS09840
uniprot id: A0A0G3X8V3
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS13830
gene id: 543877:AM2010_RS13830
uniprot id: A0A0G3XCY5
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS13225
gene id: 543877:AM2010_RS13225
uniprot id: A0A0G3XAW8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

543877:AM2010 RS00720
gene id: 543877:AM2010_RS00720
uniprot id: A0A0G3X788
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

543877:AM2010 RS04085
gene id: 543877:AM2010_RS04085
uniprot id: A0A0G3X913
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

543877:AM2010 RS02375
gene id: 543877:AM2010_RS02375
uniprot id: A0A0G3X7H9
names: Similarity
messages: Belongs to the GST superfamily.

543877:AM2010 RS06305
gene id: 543877:AM2010_RS06305
uniprot id: A0A0G3X6Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

543877:AM2010 RS12445
gene id: 543877:AM2010_RS12445
uniprot id: A0A0G3XBK4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

543877:AM2010 RS12950
gene id: 543877:AM2010_RS12950
uniprot id: A0A0G3XAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

543877:AM2010 RS03795
gene id: 543877:AM2010_RS03795
uniprot id: A0A0G3X5P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

543877:AM2010 RS12460
gene id: 543877:AM2010_RS12460
uniprot id: A0A0G3XAI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

543877:AM2010 RS06570
gene id: 543877:AM2010_RS06570
uniprot id: A0A0G3X9R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

543877:AM2010 RS07600
gene id: 543877:AM2010_RS07600
uniprot id: A0A0G3XAF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

543877:AM2010 RS07575
gene id: 543877:AM2010_RS07575
uniprot id: A0A0G3XAF2
names: Similarity
messages: Belongs to the peptidase S1B family.

543877:AM2010 RS10045
gene id: 543877:AM2010_RS10045
uniprot id: A0A0G3XBR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

543877:AM2010 RS10645
gene id: 543877:AM2010_RS10645
uniprot id: A0A0G3XAE9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

543877:AM2010 RS00710
gene id: 543877:AM2010_RS00710
uniprot id: A0A0G3X6I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

543877:AM2010 RS03955
gene id: 543877:AM2010_RS03955
uniprot id: A0A0G3X5R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

543877:AM2010 RS11145
gene id: 543877:AM2010_RS11145
uniprot id: A0A0G3XCA9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

543877:AM2010 RS06085
gene id: 543877:AM2010_RS06085
uniprot id: A0A0G3X7V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

543877:AM2010 RS08200
gene id: 543877:AM2010_RS08200
uniprot id: A0A0G3X919
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS07000
gene id: 543877:AM2010_RS07000
uniprot id: A0A0G3X8D1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS04805
gene id: 543877:AM2010_RS04805
uniprot id: A0A0G3X8W2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

543877:AM2010 RS04970
gene id: 543877:AM2010_RS04970
uniprot id: A0A0G3X7C9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

543877:AM2010 RS02625
gene id: 543877:AM2010_RS02625
uniprot id: A0A0G3X7M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

543877:AM2010 RS06370
gene id: 543877:AM2010_RS06370
uniprot id: A0A0G3X807
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

543877:AM2010 RS07625
gene id: 543877:AM2010_RS07625
uniprot id: A0A0G3XAG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

543877:AM2010 RS06985
gene id: 543877:AM2010_RS06985
uniprot id: A0A0G3XA12
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

543877:AM2010 RS06210
gene id: 543877:AM2010_RS06210
uniprot id: A0A0G3X7Y1
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

543877:AM2010 RS05415
gene id: 543877:AM2010_RS05415
uniprot id: A0A0G3X6I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

543877:AM2010 RS10140
gene id: 543877:AM2010_RS10140
uniprot id: A0A0G3X972
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

543877:AM2010 RS11980
gene id: 543877:AM2010_RS11980
uniprot id: A0A0G3XB60
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

543877:AM2010 RS13190
gene id: 543877:AM2010_RS13190
uniprot id: A0A0G3XBW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

543877:AM2010 RS10075
gene id: 543877:AM2010_RS10075
uniprot id: A0A0G3XA68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

543877:AM2010 RS05090
gene id: 543877:AM2010_RS05090
uniprot id: A0A0G3X905
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

543877:AM2010 RS04545
gene id: 543877:AM2010_RS04545
uniprot id: A0A0G3X9A9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

543877:AM2010 RS10170
gene id: 543877:AM2010_RS10170
uniprot id: A0A0G3XBT3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

543877:AM2010 RS02050
gene id: 543877:AM2010_RS02050
uniprot id: A0A0G3X7X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

543877:AM2010 RS03730
gene id: 543877:AM2010_RS03730
uniprot id: A0A0G3X6K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

543877:AM2010 RS02735
gene id: 543877:AM2010_RS02735
uniprot id: A0A0G3X8G1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

543877:AM2010 RS08145
gene id: 543877:AM2010_RS08145
uniprot id: A0A0G3XAN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS00620
gene id: 543877:AM2010_RS00620
uniprot id: A0A0G3X774
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

543877:AM2010 RS03755
gene id: 543877:AM2010_RS03755
uniprot id: A0A0G3X6K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

543877:AM2010 RS07470
gene id: 543877:AM2010_RS07470
uniprot id: A0A0G3XB23
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

543877:AM2010 RS02705
gene id: 543877:AM2010_RS02705
uniprot id: A0A0G3X607
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

543877:AM2010 RS08845
gene id: 543877:AM2010_RS08845
uniprot id: A0A0G3X8D4
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

543877:AM2010 RS01550
gene id: 543877:AM2010_RS01550
uniprot id: A0A0G3X4C3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

543877:AM2010 RS02390
gene id: 543877:AM2010_RS02390
uniprot id: A0A0G3X7J6
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

543877:AM2010 RS11265
gene id: 543877:AM2010_RS11265
uniprot id: A0A0G3XCH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

543877:AM2010 RS04770
gene id: 543877:AM2010_RS04770
uniprot id: A0A0G3X9L0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

543877:AM2010 RS10690
gene id: 543877:AM2010_RS10690
uniprot id: A0A0G3X9H0
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

543877:AM2010 RS06110
gene id: 543877:AM2010_RS06110
uniprot id: A0A0G3X7V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

543877:AM2010 RS13180
gene id: 543877:AM2010_RS13180
uniprot id: A0A0G3XAW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

543877:AM2010 RS05085
gene id: 543877:AM2010_RS05085
uniprot id: A0A0G3X9R5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543877:AM2010 RS00355
gene id: 543877:AM2010_RS00355
uniprot id: A0A0G3X3R9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

543877:AM2010 RS07005
gene id: 543877:AM2010_RS07005
uniprot id: A0A0G3XAN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

543877:AM2010 RS10260
gene id: 543877:AM2010_RS10260
uniprot id: A0A0G3XBX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

543877:AM2010 RS12510
gene id: 543877:AM2010_RS12510
uniprot id: A0A0G3XD86
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

543877:AM2010 RS00295
gene id: 543877:AM2010_RS00295
uniprot id: A0A0G3X6B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

543877:AM2010 RS12800
gene id: 543877:AM2010_RS12800
uniprot id: A0A0G3XD96
names: Similarity
messages: Belongs to the UxaA family.

543877:AM2010 RS01145
gene id: 543877:AM2010_RS01145
uniprot id: A0A0G3X455
names: Function
messages: Multidrug efflux pump.

543877:AM2010 RS12260
gene id: 543877:AM2010_RS12260
uniprot id: A0A0G3XBC1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

543877:AM2010 RS01090
gene id: 543877:AM2010_RS01090
uniprot id: A0A0G3X6S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

543877:AM2010 RS01600
gene id: 543877:AM2010_RS01600
uniprot id: A0A0G3X4D1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

543877:AM2010 RS02450
gene id: 543877:AM2010_RS02450
uniprot id: A0A0G3X7J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

543877:AM2010 RS00810
gene id: 543877:AM2010_RS00810
uniprot id: A0A0G3X3Z0
names: Similarity
messages: Belongs to the peptidase S9C family.

543877:AM2010 RS02400
gene id: 543877:AM2010_RS02400
uniprot id: A0A0G3X7I3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

543877:AM2010 RS09985
gene id: 543877:AM2010_RS09985
uniprot id: A0A0G3XCF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

543877:AM2010 RS08570
gene id: 543877:AM2010_RS08570
uniprot id: A0A0G3XAV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS07030
gene id: 543877:AM2010_RS07030
uniprot id: A0A0G3XAN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

543877:AM2010 RS09900
gene id: 543877:AM2010_RS09900
uniprot id: A0A0G3XBN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

543877:AM2010 RS01845
gene id: 543877:AM2010_RS01845
uniprot id: A0A0G3X5I1
names: Similarity
messages: Belongs to the peptidase M16 family.

543877:AM2010 RS02120
gene id: 543877:AM2010_RS02120
uniprot id: A0A0G3X5P3
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

543877:AM2010 RS06665
gene id: 543877:AM2010_RS06665
uniprot id: A0A0G3X9T1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

543877:AM2010 RS13370
gene id: 543877:AM2010_RS13370
uniprot id: A0A0G3XAZ0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

543877:AM2010 RS02640
gene id: 543877:AM2010_RS02640
uniprot id: A0A0G3X7P2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

543877:AM2010 RS12790
gene id: 543877:AM2010_RS12790
uniprot id: A0A0G3XDD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

543877:AM2010 RS03920
gene id: 543877:AM2010_RS03920
uniprot id: A0A0G3X8Y7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

543877:AM2010 RS00025
gene id: 543877:AM2010_RS00025
uniprot id: A0A0G3X669
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

543877:AM2010 RS03420
gene id: 543877:AM2010_RS03420
uniprot id: A0A0G3X828
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

543877:AM2010 RS01010
gene id: 543877:AM2010_RS01010
uniprot id: A0A0G3X534
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

543877:AM2010 RS13375
gene id: 543877:AM2010_RS13375
uniprot id: A0A0G3XDK5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

543877:AM2010 RS03205
gene id: 543877:AM2010_RS03205
uniprot id: A0A0G3X5C9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

543877:AM2010 RS12960
gene id: 543877:AM2010_RS12960
uniprot id: A0A0G3XBS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS10050
gene id: 543877:AM2010_RS10050
uniprot id: A0A0G3XA64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

543877:AM2010 RS05630
gene id: 543877:AM2010_RS05630
uniprot id: A0A0G3XA10
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

543877:AM2010 RS01270
gene id: 543877:AM2010_RS01270
uniprot id: A0A0G3X6T5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

543877:AM2010 RS01930
gene id: 543877:AM2010_RS01930
uniprot id: A0A0G3X782
names: Similarity
messages: Belongs to the peptidase A24 family.

543877:AM2010 RS04695
gene id: 543877:AM2010_RS04695
uniprot id: A0A0G3X8Q7
names: Similarity
messages: Belongs to the peptidase M16 family.

543877:AM2010 RS03225
gene id: 543877:AM2010_RS03225
uniprot id: A0A0G3X8N8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS04150
gene id: 543877:AM2010_RS04150
uniprot id: A0A0G3X5U3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

543877:AM2010 RS12860
gene id: 543877:AM2010_RS12860
uniprot id: A0A0G3XE32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

543877:AM2010 RS00410
gene id: 543877:AM2010_RS00410
uniprot id: A0A0G3X742
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

543877:AM2010 RS01075
gene id: 543877:AM2010_RS01075
uniprot id: A0A0G3X6P8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

543877:AM2010 RS04365
gene id: 543877:AM2010_RS04365
uniprot id: A0A0G3X6X2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

543877:AM2010 RS06850
gene id: 543877:AM2010_RS06850
uniprot id: A0A0G3XAK1
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

543877:AM2010 RS05380
gene id: 543877:AM2010_RS05380
uniprot id: A0A0G3X956
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

543877:AM2010 RS00830
gene id: 543877:AM2010_RS00830
uniprot id: A0A0G3X6M2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

543877:AM2010 RS07070
gene id: 543877:AM2010_RS07070
uniprot id: A0A0G3X8E7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

543877:AM2010 RS02505
gene id: 543877:AM2010_RS02505
uniprot id: A0A0G3X5Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

543877:AM2010 RS02830
gene id: 543877:AM2010_RS02830
uniprot id: A0A0G3X8H9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

543877:AM2010 RS12985
gene id: 543877:AM2010_RS12985
uniprot id: A0A0G3XBS9
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

543877:AM2010 RS03275
gene id: 543877:AM2010_RS03275
uniprot id: A0A0G3X808
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

543877:AM2010 RS10420
gene id: 543877:AM2010_RS10420
uniprot id: A0A0G3XAB2
names: Similarity
messages: Belongs to the peptidase C40 family.

543877:AM2010 RS12870
gene id: 543877:AM2010_RS12870
uniprot id: A0A0G3XAQ8
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS04275
gene id: 543877:AM2010_RS04275
uniprot id: A0A0G3X8I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

543877:AM2010 RS08020
gene id: 543877:AM2010_RS08020
uniprot id: A0A0G3X8Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

543877:AM2010 RS08095
gene id: 543877:AM2010_RS08095
uniprot id: A0A0G3XAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm
messages: Part of the Type IV secretion system.

543877:AM2010 RS03255
gene id: 543877:AM2010_RS03255
uniprot id: A0A0G3X805
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

543877:AM2010 RS09825
gene id: 543877:AM2010_RS09825
uniprot id: A0A0G3XBI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS06225
gene id: 543877:AM2010_RS06225
uniprot id: A0A0G3X6X6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

543877:AM2010 RS01085
gene id: 543877:AM2010_RS01085
uniprot id: A0A0G3X7D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

543877:AM2010 RS08725
gene id: 543877:AM2010_RS08725
uniprot id: A0A0G3XBM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

543877:AM2010 RS01500
gene id: 543877:AM2010_RS01500
uniprot id: A0A0G3X6Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

543877:AM2010 RS13445
gene id: 543877:AM2010_RS13445
uniprot id: A0A0G3XB06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

543877:AM2010 RS07585
gene id: 543877:AM2010_RS07585
uniprot id: A0A0G3XAD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

543877:AM2010 RS08455
gene id: 543877:AM2010_RS08455
uniprot id: A0A0G3XBI8
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS10040
gene id: 543877:AM2010_RS10040
uniprot id: A0A0G3X951
names: Function
messages: Multidrug efflux pump.

543877:AM2010 RS08115
gene id: 543877:AM2010_RS08115
uniprot id: A0A0G3X810
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

543877:AM2010 RS04495
gene id: 543877:AM2010_RS04495
uniprot id: A0A0G3X998
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

543877:AM2010 RS11025
gene id: 543877:AM2010_RS11025
uniprot id: A0A0G3XC88
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

543877:AM2010 RS10835
gene id: 543877:AM2010_RS10835
uniprot id: A0A0G3XC94
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

543877:AM2010 RS03970
gene id: 543877:AM2010_RS03970
uniprot id: A0A0G3X8Z6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

543877:AM2010 RS11270
gene id: 543877:AM2010_RS11270
uniprot id: A0A0G3X9R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

543877:AM2010 RS06560
gene id: 543877:AM2010_RS06560
uniprot id: A0A0G3X9S8
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

543877:AM2010 RS05265
gene id: 543877:AM2010_RS05265
uniprot id: A0A0G3X9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

543877:AM2010 RS11925
gene id: 543877:AM2010_RS11925
uniprot id: A0A0G3XCR1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

543877:AM2010 RS03750
gene id: 543877:AM2010_RS03750
uniprot id: A0A0G3X871
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

543877:AM2010 RS03210
gene id: 543877:AM2010_RS03210
uniprot id: A0A0G3X7Y2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

543877:AM2010 RS01995
gene id: 543877:AM2010_RS01995
uniprot id: A0A0G3X7W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

543877:AM2010 RS01180
gene id: 543877:AM2010_RS01180
uniprot id: A0A0G3X563
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

543877:AM2010 RS03780
gene id: 543877:AM2010_RS03780
uniprot id: A0A0G3X6L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

543877:AM2010 RS05865
gene id: 543877:AM2010_RS05865
uniprot id: A0A0G3X9F1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

543877:AM2010 RS06590
gene id: 543877:AM2010_RS06590
uniprot id: A0A0G3X745
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

543877:AM2010 RS01310
gene id: 543877:AM2010_RS01310
uniprot id: A0A0G3X7H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS11625
gene id: 543877:AM2010_RS11625
uniprot id: A0A0G3XD72
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

543877:AM2010 RS08850
gene id: 543877:AM2010_RS08850
uniprot id: A0A0G3XAZ7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

543877:AM2010 RS02570
gene id: 543877:AM2010_RS02570
uniprot id: A0A0G3X4Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

543877:AM2010 RS01040
gene id: 543877:AM2010_RS01040
uniprot id: A0A0G3X6R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

543877:AM2010 RS11705
gene id: 543877:AM2010_RS11705
uniprot id: A0A0G3X9Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

543877:AM2010 RS01795
gene id: 543877:AM2010_RS01795
uniprot id: A0A0G3X5H1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

543877:AM2010 RS13835
gene id: 543877:AM2010_RS13835
uniprot id: A0A0G3XE50
names: Similarity
messages: Belongs to the thioesterase PaaI family.

543877:AM2010 RS11640
gene id: 543877:AM2010_RS11640
uniprot id: A0A0G3XAY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

543877:AM2010 RS08830
gene id: 543877:AM2010_RS08830
uniprot id: A0A0G3XBN5
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS04400
gene id: 543877:AM2010_RS04400
uniprot id: A0A0G3X8K3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

543877:AM2010 RS08185
gene id: 543877:AM2010_RS08185
uniprot id: A0A0G3XAR4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS03110
gene id: 543877:AM2010_RS03110
uniprot id: A0A0G3X663
names: Similarity
messages: Belongs to the UPF0758 family.

543877:AM2010 RS04680
gene id: 543877:AM2010_RS04680
uniprot id: A0A0G3X8P3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

543877:AM2010 RS00605
gene id: 543877:AM2010_RS00605
uniprot id: A0A0G3X3W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

543877:AM2010 RS04890
gene id: 543877:AM2010_RS04890
uniprot id: A0A0G3X8W8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

543877:AM2010 RS07900
gene id: 543877:AM2010_RS07900
uniprot id: A0A0G3XBA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

543877:AM2010 RS03475
gene id: 543877:AM2010_RS03475
uniprot id: A0A0G3X835
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

543877:AM2010 RS05295
gene id: 543877:AM2010_RS05295
uniprot id: A0A0G3X940
names: Similarity
messages: Belongs to the thioesterase PaaI family.

543877:AM2010 RS00645
gene id: 543877:AM2010_RS00645
uniprot id: A0A0G3X777
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

543877:AM2010 RS10185
gene id: 543877:AM2010_RS10185
uniprot id: A0A0G3XBW2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS09360
gene id: 543877:AM2010_RS09360
uniprot id: A0A0G3XBC9
names: Similarity
messages: Belongs to the peptidase S58 family.

543877:AM2010 RS04690
gene id: 543877:AM2010_RS04690
uniprot id: A0A0G3X9E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS11515
gene id: 543877:AM2010_RS11515
uniprot id: A0A0G3XD59
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

543877:AM2010 RS11780
gene id: 543877:AM2010_RS11780
uniprot id: A0A0G3XA11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS04510
gene id: 543877:AM2010_RS04510
uniprot id: A0A0G3X8L4
names: Similarity
messages: Belongs to the UPF0102 family.

543877:AM2010 RS06600
gene id: 543877:AM2010_RS06600
uniprot id: A0A0G3XAF1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

543877:AM2010 RS13295
gene id: 543877:AM2010_RS13295
uniprot id: A0A0G3XEA8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

543877:AM2010 RS02525
gene id: 543877:AM2010_RS02525
uniprot id: A0A0G3X7K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

543877:AM2010 RS09200
gene id: 543877:AM2010_RS09200
uniprot id: A0A0G3X9J8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS06630
gene id: 543877:AM2010_RS06630
uniprot id: A0A0G3X9U2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

543877:AM2010 RS04290
gene id: 543877:AM2010_RS04290
uniprot id: A0A0G3X6V7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

543877:AM2010 RS13555
gene id: 543877:AM2010_RS13555
uniprot id: A0A0G3XC38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

543877:AM2010 RS04155
gene id: 543877:AM2010_RS04155
uniprot id: A0A0G3X8E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

543877:AM2010 RS02740
gene id: 543877:AM2010_RS02740
uniprot id: A0A0G3X7R0
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

543877:AM2010 RS07715
gene id: 543877:AM2010_RS07715
uniprot id: A0A0G3X8U2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

543877:AM2010 RS10530
gene id: 543877:AM2010_RS10530
uniprot id: A0A0G3XCQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

543877:AM2010 RS05400
gene id: 543877:AM2010_RS05400
uniprot id: A0A0G3X9X1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS09990
gene id: 543877:AM2010_RS09990
uniprot id: A0A0G3XBT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

543877:AM2010 RS12490
gene id: 543877:AM2010_RS12490
uniprot id: A0A0G3XAJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

543877:AM2010 RS08210
gene id: 543877:AM2010_RS08210
uniprot id: A0A0G3XAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

543877:AM2010 RS02775
gene id: 543877:AM2010_RS02775
uniprot id: A0A0G3X617
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

543877:AM2010 RS07790
gene id: 543877:AM2010_RS07790
uniprot id: A0A0G3X8V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

543877:AM2010 RS03305
gene id: 543877:AM2010_RS03305
uniprot id: A0A0G3X5E8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

543877:AM2010 RS05220
gene id: 543877:AM2010_RS05220
uniprot id: A0A0G3X925
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

543877:AM2010 RS01635
gene id: 543877:AM2010_RS01635
uniprot id: A0A0G3X706
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

543877:AM2010 RS05625
gene id: 543877:AM2010_RS05625
uniprot id: A0A0G3X7L6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

543877:AM2010 RS02920
gene id: 543877:AM2010_RS02920
uniprot id: A0A0G3X564
names: Similarity
messages: Belongs to the CFA/CMAS family.

543877:AM2010 RS13565
gene id: 543877:AM2010_RS13565
uniprot id: A0A0G3XDS1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

543877:AM2010 RS04515
gene id: 543877:AM2010_RS04515
uniprot id: A0A0G3X703
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

543877:AM2010 RS03865
gene id: 543877:AM2010_RS03865
uniprot id: A0A0G3X8X8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

543877:AM2010 RS13465
gene id: 543877:AM2010_RS13465
uniprot id: A0A0G3XDQ6
names: Similarity
messages: Belongs to the YkuD family.

543877:AM2010 RS02825
gene id: 543877:AM2010_RS02825
uniprot id: A0A0G3X625
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

543877:AM2010 RS11615
gene id: 543877:AM2010_RS11615
uniprot id: A0A0G3XCJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

543877:AM2010 RS01005
gene id: 543877:AM2010_RS01005
uniprot id: A0A0G3X6N2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

543877:AM2010 RS04910
gene id: 543877:AM2010_RS04910
uniprot id: A0A0G3X6A0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

543877:AM2010 RS10155
gene id: 543877:AM2010_RS10155
uniprot id: A0A0G3XCJ1
names: Similarity
messages: Belongs to the peptidase U62 family.

543877:AM2010 RS11585
gene id: 543877:AM2010_RS11585
uniprot id: A0A0G3XCI9
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS08370
gene id: 543877:AM2010_RS08370
uniprot id: A0A0G3XBH7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS07995
gene id: 543877:AM2010_RS07995
uniprot id: A0A0G3X8Y6
names: Similarity
messages: Belongs to the sterol desaturase family.

543877:AM2010 RS11855
gene id: 543877:AM2010_RS11855
uniprot id: A0A0G3XB34
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

543877:AM2010 RS06970
gene id: 543877:AM2010_RS06970
uniprot id: A0A0G3X9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS09290
gene id: 543877:AM2010_RS09290
uniprot id: A0A0G3XB84
names: Similarity
messages: Belongs to the UPF0260 family.

543877:AM2010 RS00715
gene id: 543877:AM2010_RS00715
uniprot id: A0A0G3X4Y7
names: Similarity
messages: Belongs to the type III secretion exporter family.

543877:AM2010 RS06705
gene id: 543877:AM2010_RS06705
uniprot id: A0A0G3X9V9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

543877:AM2010 RS04615
gene id: 543877:AM2010_RS04615
uniprot id: A0A0G3X725
names: Similarity
messages: Belongs to the alanine racemase family.

543877:AM2010 RS02165
gene id: 543877:AM2010_RS02165
uniprot id: A0A0G3X7E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS00800
gene id: 543877:AM2010_RS00800
uniprot id: A0A0G3X7A0
names: Similarity
messages: Belongs to the lycopene cyclase family.

543877:AM2010 RS02280
gene id: 543877:AM2010_RS02280
uniprot id: A0A0G3X875
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

543877:AM2010 RS12290
gene id: 543877:AM2010_RS12290
uniprot id: A0A0G3XBC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

543877:AM2010 RS05945
gene id: 543877:AM2010_RS05945
uniprot id: A0A0G3X6S3
names: Similarity
messages: Belongs to the DEAD box helicase family.

543877:AM2010 RS03840
gene id: 543877:AM2010_RS03840
uniprot id: A0A0G3X8A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

543877:AM2010 RS11880
gene id: 543877:AM2010_RS11880
uniprot id: A0A0G3XB39
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

543877:AM2010 RS01205
gene id: 543877:AM2010_RS01205
uniprot id: A0A0G3X566
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

543877:AM2010 RS03435
gene id: 543877:AM2010_RS03435
uniprot id: A0A0G3X6F4
names: Similarity
messages: Belongs to the YoeB family.

543877:AM2010 RS01465
gene id: 543877:AM2010_RS01465
uniprot id: A0A0G3X6Z4
names: Similarity
messages: Belongs to the pirin family.

543877:AM2010 RS09785
gene id: 543877:AM2010_RS09785
uniprot id: A0A0G3X9X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

543877:AM2010 RS13195
gene id: 543877:AM2010_RS13195
uniprot id: A0A0G3XE92
names: Similarity
messages: Belongs to the cytochrome P450 family.

543877:AM2010 RS09880
gene id: 543877:AM2010_RS09880
uniprot id: A0A0G3X9Z4
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

543877:AM2010 RS10570
gene id: 543877:AM2010_RS10570
uniprot id: A0A0G3XC00
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

543877:AM2010 RS02805
gene id: 543877:AM2010_RS02805
uniprot id: A0A0G3X8H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS01440
gene id: 543877:AM2010_RS01440
uniprot id: A0A0G3X6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

543877:AM2010 RS03675
gene id: 543877:AM2010_RS03675
uniprot id: A0A0G3X853
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

543877:AM2010 RS11505
gene id: 543877:AM2010_RS11505
uniprot id: A0A0G3XCH5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

543877:AM2010 RS07010
gene id: 543877:AM2010_RS07010
uniprot id: A0A0G3XA17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

543877:AM2010 RS05350
gene id: 543877:AM2010_RS05350
uniprot id: A0A0G3X950
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

543877:AM2010 RS06485
gene id: 543877:AM2010_RS06485
uniprot id: A0A0G3X9R3
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS01880
gene id: 543877:AM2010_RS01880
uniprot id: A0A0G3X772
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

543877:AM2010 RS02695
gene id: 543877:AM2010_RS02695
uniprot id: A0A0G3X535
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

543877:AM2010 RS07925
gene id: 543877:AM2010_RS07925
uniprot id: A0A0G3XBA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

543877:AM2010 RS10230
gene id: 543877:AM2010_RS10230
uniprot id: A0A0G3XCK2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

543877:AM2010 RS04255
gene id: 543877:AM2010_RS04255
uniprot id: A0A0G3X8G5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

543877:AM2010 RS03030
gene id: 543877:AM2010_RS03030
uniprot id: A0A0G3X7V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

543877:AM2010 RS13505
gene id: 543877:AM2010_RS13505
uniprot id: A0A0G3XC26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

543877:AM2010 RS10890
gene id: 543877:AM2010_RS10890
uniprot id: A0A0G3X9J9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

543877:AM2010 RS08170
gene id: 543877:AM2010_RS08170
uniprot id: A0A0G3XAN6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543877:AM2010 RS06090
gene id: 543877:AM2010_RS06090
uniprot id: A0A0G3XA75
names: Similarity
messages: Belongs to the TrpF family.

543877:AM2010 RS03130
gene id: 543877:AM2010_RS03130
uniprot id: A0A0G3X7W9
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

543877:AM2010 RS04475
gene id: 543877:AM2010_RS04475
uniprot id: A0A0G3X8L7
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

543877:AM2010 RS11075
gene id: 543877:AM2010_RS11075
uniprot id: A0A0G3XAN5
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS02495
gene id: 543877:AM2010_RS02495
uniprot id: A0A0G3X4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

543877:AM2010 RS07635
gene id: 543877:AM2010_RS07635
uniprot id: A0A0G3XAE2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543877:AM2010 RS01160
gene id: 543877:AM2010_RS01160
uniprot id: A0A0G3X7E8
names: Similarity
messages: Belongs to the ArsC family.

543877:AM2010 RS03705
gene id: 543877:AM2010_RS03705
uniprot id: A0A0G3X6J9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS04625
gene id: 543877:AM2010_RS04625
uniprot id: A0A0G3X8P1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

543877:AM2010 RS00610
gene id: 543877:AM2010_RS00610
uniprot id: A0A0G3X6G5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

543877:AM2010 RS02485
gene id: 543877:AM2010_RS02485
uniprot id: A0A0G3X8B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

543877:AM2010 RS11510
gene id: 543877:AM2010_RS11510
uniprot id: A0A0G3XAW6
names: Similarity
messages: Belongs to the RNase T2 family.

543877:AM2010 RS13420
gene id: 543877:AM2010_RS13420
uniprot id: A0A0G3XB00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

543877:AM2010 RS05040
gene id: 543877:AM2010_RS05040
uniprot id: A0A0G3X8Z7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS04980
gene id: 543877:AM2010_RS04980
uniprot id: A0A0G3X8Y8
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

543877:AM2010 RS09775
gene id: 543877:AM2010_RS09775
uniprot id: A0A0G3X8U1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

543877:AM2010 RS09715
gene id: 543877:AM2010_RS09715
uniprot id: A0A0G3XC50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

543877:AM2010 RS07660
gene id: 543877:AM2010_RS07660
uniprot id: A0A0G3XAE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

543877:AM2010 RS09600
gene id: 543877:AM2010_RS09600
uniprot id: A0A0G3XBE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.

543877:AM2010 RS12300
gene id: 543877:AM2010_RS12300
uniprot id: A0A0G3XD06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

543877:AM2010 RS01275
gene id: 543877:AM2010_RS01275
uniprot id: A0A0G3X574
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS12855
gene id: 543877:AM2010_RS12855
uniprot id: A0A0G3XBQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

543877:AM2010 RS06605
gene id: 543877:AM2010_RS06605
uniprot id: A0A0G3X9T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

543877:AM2010 RS02285
gene id: 543877:AM2010_RS02285
uniprot id: A0A0G3X7I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

543877:AM2010 RS03685
gene id: 543877:AM2010_RS03685
uniprot id: A0A0G3X8U6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS10930
gene id: 543877:AM2010_RS10930
uniprot id: A0A0G3XCX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS08160
gene id: 543877:AM2010_RS08160
uniprot id: A0A0G3XAR0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS05600
gene id: 543877:AM2010_RS05600
uniprot id: A0A0G3X7L1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543877:AM2010 RS13520
gene id: 543877:AM2010_RS13520
uniprot id: A0A0G3XB21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

543877:AM2010 RS04815
gene id: 543877:AM2010_RS04815
uniprot id: A0A0G3X8V6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

543877:AM2010 RS09010
gene id: 543877:AM2010_RS09010
uniprot id: A0A0G3XB57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS03715
gene id: 543877:AM2010_RS03715
uniprot id: A0A0G3X878
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

543877:AM2010 RS07080
gene id: 543877:AM2010_RS07080
uniprot id: A0A0G3XA28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

543877:AM2010 RS00955
gene id: 543877:AM2010_RS00955
uniprot id: A0A0G3X6M4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

543877:AM2010 RS02555
gene id: 543877:AM2010_RS02555
uniprot id: A0A0G3X5Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

543877:AM2010 RS00975
gene id: 543877:AM2010_RS00975
uniprot id: A0A0G3X419
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS02605
gene id: 543877:AM2010_RS02605
uniprot id: A0A0G3X5Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

543877:AM2010 RS03825
gene id: 543877:AM2010_RS03825
uniprot id: A0A0G3X884
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

543877:AM2010 RS08550
gene id: 543877:AM2010_RS08550
uniprot id: A0A0G3X983
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

543877:AM2010 RS00515
gene id: 543877:AM2010_RS00515
uniprot id: A0A0G3X6H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

543877:AM2010 RS05510
gene id: 543877:AM2010_RS05510
uniprot id: A0A0G3X981
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

543877:AM2010 RS02345
gene id: 543877:AM2010_RS02345
uniprot id: A0A0G3X7H5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

543877:AM2010 RS02615
gene id: 543877:AM2010_RS02615
uniprot id: A0A0G3X7N6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

543877:AM2010 RS03810
gene id: 543877:AM2010_RS03810
uniprot id: A0A0G3X8X0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

543877:AM2010 RS03765
gene id: 543877:AM2010_RS03765
uniprot id: A0A0G3X885
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

543877:AM2010 RS02575
gene id: 543877:AM2010_RS02575
uniprot id: A0A0G3X7L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

543877:AM2010 RS05185
gene id: 543877:AM2010_RS05185
uniprot id: A0A0G3X9T2
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS06845
gene id: 543877:AM2010_RS06845
uniprot id: A0A0G3X898
names: Similarity
messages: Belongs to the virb1 family.

543877:AM2010 RS00750
gene id: 543877:AM2010_RS00750
uniprot id: A0A0G3X792
names: Similarity
messages: Belongs to the Dps family.

543877:AM2010 RS02145
gene id: 543877:AM2010_RS02145
uniprot id: A0A0G3X5P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

543877:AM2010 RS13215
gene id: 543877:AM2010_RS13215
uniprot id: A0A0G3XE96
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

543877:AM2010 RS04175
gene id: 543877:AM2010_RS04175
uniprot id: A0A0G3X5U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

543877:AM2010 RS02590
gene id: 543877:AM2010_RS02590
uniprot id: A0A0G3X7N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

543877:AM2010 RS06745
gene id: 543877:AM2010_RS06745
uniprot id: A0A0G3X877
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

543877:AM2010 RS04485
gene id: 543877:AM2010_RS04485
uniprot id: A0A0G3X8K9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

543877:AM2010 RS10330
gene id: 543877:AM2010_RS10330
uniprot id: A0A0G3XCM1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

543877:AM2010 RS09020
gene id: 543877:AM2010_RS09020
uniprot id: A0A0G3XB32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

543877:AM2010 RS12215
gene id: 543877:AM2010_RS12215
uniprot id: A0A0G3XDJ5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

543877:AM2010 RS01730
gene id: 543877:AM2010_RS01730
uniprot id: A0A0G3X4E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS00965
gene id: 543877:AM2010_RS00965
uniprot id: A0A0G3X7C4
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

543877:AM2010 RS02180
gene id: 543877:AM2010_RS02180
uniprot id: A0A0G3X7G4
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS13475
gene id: 543877:AM2010_RS13475
uniprot id: A0A0G3XDM6
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

543877:AM2010 RS12425
gene id: 543877:AM2010_RS12425
uniprot id: A0A0G3XD75
names: Similarity
messages: Belongs to the peptidase M24B family.

543877:AM2010 RS10945
gene id: 543877:AM2010_RS10945
uniprot id: A0A0G3XC74
names: Similarity
messages: Belongs to the PhzF family.

543877:AM2010 RS10030
gene id: 543877:AM2010_RS10030
uniprot id: A0A0G3XCG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

543877:AM2010 RS08915
gene id: 543877:AM2010_RS08915
uniprot id: A0A0G3XB35
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is located at the dimer interface.

543877:AM2010 RS13545
gene id: 543877:AM2010_RS13545
uniprot id: A0A0G3XB27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

543877:AM2010 RS10730
gene id: 543877:AM2010_RS10730
uniprot id: A0A0G3XCU5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

543877:AM2010 RS01955
gene id: 543877:AM2010_RS01955
uniprot id: A0A0G3X4H8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

543877:AM2010 RS05065
gene id: 543877:AM2010_RS05065
uniprot id: A0A0G3X901
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

543877:AM2010 RS11995
gene id: 543877:AM2010_RS11995
uniprot id: A0A0G3XA52
names: Similarity
messages: Belongs to the peptidase S9C family.

543877:AM2010 RS04285
gene id: 543877:AM2010_RS04285
uniprot id: A0A0G3X8G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

543877:AM2010 RS03845
gene id: 543877:AM2010_RS03845
uniprot id: A0A0G3X5Q0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS04280
gene id: 543877:AM2010_RS04280
uniprot id: A0A0G3X5W1
names: Similarity
messages: Belongs to the MreC family.

543877:AM2010 RS02410
gene id: 543877:AM2010_RS02410
uniprot id: A0A0G3X8A0
names: Similarity
messages: Belongs to the TlyA family.

543877:AM2010 RS08640
gene id: 543877:AM2010_RS08640
uniprot id: A0A0G3XBL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

543877:AM2010 RS03185
gene id: 543877:AM2010_RS03185
uniprot id: A0A0G3X675
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

543877:AM2010 RS11320
gene id: 543877:AM2010_RS11320
uniprot id: A0A0G3X9T0
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

543877:AM2010 RS00585
gene id: 543877:AM2010_RS00585
uniprot id: A0A0G3X6G1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

543877:AM2010 RS05710
gene id: 543877:AM2010_RS05710
uniprot id: A0A0G3X6N1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

543877:AM2010 RS08760
gene id: 543877:AM2010_RS08760
uniprot id: A0A0G3X8C3
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS07730
gene id: 543877:AM2010_RS07730
uniprot id: A0A0G3X7U2
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

543877:AM2010 RS05620
gene id: 543877:AM2010_RS05620
uniprot id: A0A0G3X989
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

543877:AM2010 RS05485
gene id: 543877:AM2010_RS05485
uniprot id: A0A0G3X975
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

543877:AM2010 RS05225
gene id: 543877:AM2010_RS05225
uniprot id: A0A0G3X6F3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

543877:AM2010 RS08415
gene id: 543877:AM2010_RS08415
uniprot id: A0A0G3X958
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

543877:AM2010 RS05875
gene id: 543877:AM2010_RS05875
uniprot id: A0A0G3X9D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

543877:AM2010 RS01900
gene id: 543877:AM2010_RS01900
uniprot id: A0A0G3X7T9
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS12320
gene id: 543877:AM2010_RS12320
uniprot id: A0A0G3XDL9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS07825
gene id: 543877:AM2010_RS07825
uniprot id: A0A0G3XB91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

543877:AM2010 RS01780
gene id: 543877:AM2010_RS01780
uniprot id: A0A0G3X756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

543877:AM2010 RS06055
gene id: 543877:AM2010_RS06055
uniprot id: A0A0G3X9G8
names: Similarity
messages: Belongs to the virb1 family.

543877:AM2010 RS11475
gene id: 543877:AM2010_RS11475
uniprot id: A0A0G3X9V6
names: Similarity
messages: Belongs to the GARS family.

543877:AM2010 RS01990
gene id: 543877:AM2010_RS01990
uniprot id: A0A0G3X5L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

543877:AM2010 RS06620
gene id: 543877:AM2010_RS06620
uniprot id: A0A0G3X851
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

543877:AM2010 RS11205
gene id: 543877:AM2010_RS11205
uniprot id: A0A0G3XAR1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

543877:AM2010 RS10580
gene id: 543877:AM2010_RS10580
uniprot id: A0A0G3XCR6
names: Similarity
messages: Belongs to the FBPase class 2 family.

543877:AM2010 RS11575
gene id: 543877:AM2010_RS11575
uniprot id: A0A0G3XCM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

543877:AM2010 RS06540
gene id: 543877:AM2010_RS06540
uniprot id: A0A0G3X736
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS06415
gene id: 543877:AM2010_RS06415
uniprot id: A0A0G3X9N1
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

543877:AM2010 RS12525
gene id: 543877:AM2010_RS12525
uniprot id: A0A0G3XBL7
names: Subcellular Location Annotation
messages: Mitochondrion

543877:AM2010 RS00055
gene id: 543877:AM2010_RS00055
uniprot id: A0A0G3X673
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS08580
gene id: 543877:AM2010_RS08580
uniprot id: A0A0G3XBK6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

543877:AM2010 RS07480
gene id: 543877:AM2010_RS07480
uniprot id: A0A0G3X7P5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

543877:AM2010 RS03300
gene id: 543877:AM2010_RS03300
uniprot id: A0A0G3X813
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

543877:AM2010 RS13155
gene id: 543877:AM2010_RS13155
uniprot id: A0A0G3XAV8
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

543877:AM2010 RS13330
gene id: 543877:AM2010_RS13330
uniprot id: A0A0G3XBY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

543877:AM2010 RS01690
gene id: 543877:AM2010_RS01690
uniprot id: A0A0G3X5F0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

543877:AM2010 RS13040
gene id: 543877:AM2010_RS13040
uniprot id: A0A0G3XE65
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

543877:AM2010 RS12725
gene id: 543877:AM2010_RS12725
uniprot id: A0A0G3XD84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

543877:AM2010 RS04750
gene id: 543877:AM2010_RS04750
uniprot id: A0A0G3X8V2
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

543877:AM2010 RS02045
gene id: 543877:AM2010_RS02045
uniprot id: A0A0G3X5M8
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

543877:AM2010 RS02730
gene id: 543877:AM2010_RS02730
uniprot id: A0A0G3X610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS01225
gene id: 543877:AM2010_RS01225
uniprot id: A0A0G3X6S4
names: Similarity
messages: Belongs to the FGGY kinase family.

543877:AM2010 RS08885
gene id: 543877:AM2010_RS08885
uniprot id: A0A0G3XBP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

543877:AM2010 RS06235
gene id: 543877:AM2010_RS06235
uniprot id: A0A0G3X7Y6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS07065
gene id: 543877:AM2010_RS07065
uniprot id: A0A0G3XA09
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

543877:AM2010 RS09870
gene id: 543877:AM2010_RS09870
uniprot id: A0A0G3X8V9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

543877:AM2010 RS06820
gene id: 543877:AM2010_RS06820
uniprot id: A0A0G3X892
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS03230
gene id: 543877:AM2010_RS03230
uniprot id: A0A0G3X801
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

543877:AM2010 RS00510
gene id: 543877:AM2010_RS00510
uniprot id: A0A0G3X759
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

543877:AM2010 RS12920
gene id: 543877:AM2010_RS12920
uniprot id: A0A0G3XAR8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

543877:AM2010 RS02750
gene id: 543877:AM2010_RS02750
uniprot id: A0A0G3X7P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

543877:AM2010 RS05385
gene id: 543877:AM2010_RS05385
uniprot id: A0A0G3X6I0
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

543877:AM2010 RS14440
gene id: 543877:AM2010_RS14440
uniprot id: A0A0G3XBE4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

543877:AM2010 RS07445
gene id: 543877:AM2010_RS07445
uniprot id: A0A0G3XB19
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

543877:AM2010 RS12110
gene id: 543877:AM2010_RS12110
uniprot id: A0A0G3XB88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

543877:AM2010 RS04165
gene id: 543877:AM2010_RS04165
uniprot id: A0A0G3X926
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

543877:AM2010 RS05980
gene id: 543877:AM2010_RS05980
uniprot id: A0A0G3X9F7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

543877:AM2010 RS06060
gene id: 543877:AM2010_RS06060
uniprot id: A0A0G3X7U9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

543877:AM2010 RS13270
gene id: 543877:AM2010_RS13270
uniprot id: A0A0G3XEA3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS01715
gene id: 543877:AM2010_RS01715
uniprot id: A0A0G3X5F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

543877:AM2010 RS06675
gene id: 543877:AM2010_RS06675
uniprot id: A0A0G3XAG3
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

543877:AM2010 RS12740
gene id: 543877:AM2010_RS12740
uniprot id: A0A0G3XDC3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

543877:AM2010 RS10970
gene id: 543877:AM2010_RS10970
uniprot id: A0A0G3XC78
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

543877:AM2010 RS10750
gene id: 543877:AM2010_RS10750
uniprot id: A0A0G3XAG5
names: Subunit
messages: Homotetramer.

543877:AM2010 RS02630
gene id: 543877:AM2010_RS02630
uniprot id: A0A0G3X5Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

543877:AM2010 RS00705
gene id: 543877:AM2010_RS00705
uniprot id: A0A0G3X3X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

543877:AM2010 RS06565
gene id: 543877:AM2010_RS06565
uniprot id: A0A0G3X741
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

543877:AM2010 RS01590
gene id: 543877:AM2010_RS01590
uniprot id: A0A0G3X7M3
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

543877:AM2010 RS11400
gene id: 543877:AM2010_RS11400
uniprot id: A0A0G3X9U4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

543877:AM2010 RS05735
gene id: 543877:AM2010_RS05735
uniprot id: A0A0G3XA23
names: Similarity
messages: Belongs to the CcdB toxin family.

543877:AM2010 RS00505
gene id: 543877:AM2010_RS00505
uniprot id: A0A0G3X4V0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

543877:AM2010 RS12850
gene id: 543877:AM2010_RS12850
uniprot id: A0A0G3XDA4
names: Similarity
messages: Belongs to the GcvT family.

543877:AM2010 RS03965
gene id: 543877:AM2010_RS03965
uniprot id: A0A0G3X6P5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

543877:AM2010 RS12900
gene id: 543877:AM2010_RS12900
uniprot id: A0A0G3XDB2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS08070
gene id: 543877:AM2010_RS08070
uniprot id: A0A0G3X900
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

543877:AM2010 RS03720
gene id: 543877:AM2010_RS03720
uniprot id: A0A0G3X5M4
names: Similarity
messages: Belongs to the Skp family.

543877:AM2010 RS02530
gene id: 543877:AM2010_RS02530
uniprot id: A0A0G3X5Y4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

543877:AM2010 RS03570
gene id: 543877:AM2010_RS03570
uniprot id: A0A0G3X6H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

543877:AM2010 RS01745
gene id: 543877:AM2010_RS01745
uniprot id: A0A0G3X7Q7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS10510
gene id: 543877:AM2010_RS10510
uniprot id: A0A0G3XC28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS05595
gene id: 543877:AM2010_RS05595
uniprot id: A0A0G3X985
names: Similarity
messages: Belongs to the pirin family.

543877:AM2010 RS04610
gene id: 543877:AM2010_RS04610
uniprot id: A0A0G3X8N1
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS12695
gene id: 543877:AM2010_RS12695
uniprot id: A0A0G3XAM5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

543877:AM2010 RS05525
gene id: 543877:AM2010_RS05525
uniprot id: A0A0G3X7K0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

543877:AM2010 RS02550
gene id: 543877:AM2010_RS02550
uniprot id: A0A0G3X7K6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

543877:AM2010 RS02600
gene id: 543877:AM2010_RS02600
uniprot id: A0A0G3X7L5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

543877:AM2010 RS11305
gene id: 543877:AM2010_RS11305
uniprot id: A0A0G3XAT0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS02060
gene id: 543877:AM2010_RS02060
uniprot id: A0A0G3X4I6
names: Similarity
messages: Belongs to the peptidase M17 family.

543877:AM2010 RS05680
gene id: 543877:AM2010_RS05680
uniprot id: A0A0G3XA15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

543877:AM2010 RS02510
gene id: 543877:AM2010_RS02510
uniprot id: A0A0G3X8B7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

543877:AM2010 RS05035
gene id: 543877:AM2010_RS05035
uniprot id: A0A0G3X9Q3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

543877:AM2010 RS07605
gene id: 543877:AM2010_RS07605
uniprot id: A0A0G3X7R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

543877:AM2010 RS00260
gene id: 543877:AM2010_RS00260
uniprot id: A0A0G3X3Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS03680
gene id: 543877:AM2010_RS03680
uniprot id: A0A0G3X6J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

543877:AM2010 RS06355
gene id: 543877:AM2010_RS06355
uniprot id: A0A0G3X700
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

543877:AM2010 RS06335
gene id: 543877:AM2010_RS06335
uniprot id: A0A0G3X9L5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

543877:AM2010 RS06480
gene id: 543877:AM2010_RS06480
uniprot id: A0A0G3XAC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

543877:AM2010 RS05310
gene id: 543877:AM2010_RS05310
uniprot id: A0A0G3X7H0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

543877:AM2010 RS06100
gene id: 543877:AM2010_RS06100
uniprot id: A0A0G3X6V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

543877:AM2010 RS08900
gene id: 543877:AM2010_RS08900
uniprot id: A0A0G3XB07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

543877:AM2010 RS02870
gene id: 543877:AM2010_RS02870
uniprot id: A0A0G3X560
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS03480
gene id: 543877:AM2010_RS03480
uniprot id: A0A0G3X5I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

543877:AM2010 RS11910
gene id: 543877:AM2010_RS11910
uniprot id: A0A0G3XDD3
names: Similarity
messages: Belongs to the CutA family.

543877:AM2010 RS06920
gene id: 543877:AM2010_RS06920
uniprot id: A0A0G3X9Y2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

543877:AM2010 RS09845
gene id: 543877:AM2010_RS09845
uniprot id: A0A0G3XBI7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

543877:AM2010 RS02490
gene id: 543877:AM2010_RS02490
uniprot id: A0A0G3X7L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

543877:AM2010 RS12335
gene id: 543877:AM2010_RS12335
uniprot id: A0A0G3XCY8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

543877:AM2010 RS03700
gene id: 543877:AM2010_RS03700
uniprot id: A0A0G3X860
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

543877:AM2010 RS10450
gene id: 543877:AM2010_RS10450
uniprot id: A0A0G3XCP3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

543877:AM2010 RS08645
gene id: 543877:AM2010_RS08645
uniprot id: A0A0G3XAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

543877:AM2010 RS00700
gene id: 543877:AM2010_RS00700
uniprot id: A0A0G3X6K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

543877:AM2010 RS11340
gene id: 543877:AM2010_RS11340
uniprot id: A0A0G3XCI6
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

543877:AM2010 RS09545
gene id: 543877:AM2010_RS09545
uniprot id: A0A0G3X8R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS10560
gene id: 543877:AM2010_RS10560
uniprot id: A0A0G3XC40
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

543877:AM2010 RS05790
gene id: 543877:AM2010_RS05790
uniprot id: A0A0G3X6P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS10825
gene id: 543877:AM2010_RS10825
uniprot id: A0A0G3XAH7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

543877:AM2010 RS06005
gene id: 543877:AM2010_RS06005
uniprot id: A0A0G3X9G0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

543877:AM2010 RS00520
gene id: 543877:AM2010_RS00520
uniprot id: A0A0G3X3U9
names: Similarity
messages: Belongs to the MotB family.

543877:AM2010 RS07885
gene id: 543877:AM2010_RS07885
uniprot id: A0A0G3X7X0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

543877:AM2010 RS10265
gene id: 543877:AM2010_RS10265
uniprot id: A0A0G3X995
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

543877:AM2010 RS04245
gene id: 543877:AM2010_RS04245
uniprot id: A0A0G3X8H6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

543877:AM2010 RS00470
gene id: 543877:AM2010_RS00470
uniprot id: A0A0G3X3U0
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

543877:AM2010 RS13160
gene id: 543877:AM2010_RS13160
uniprot id: A0A0G3XDG6
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

543877:AM2010 RS09590
gene id: 543877:AM2010_RS09590
uniprot id: A0A0G3XBH2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

543877:AM2010 RS05490
gene id: 543877:AM2010_RS05490
uniprot id: A0A0G3X6J7
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

543877:AM2010 RS12600
gene id: 543877:AM2010_RS12600
uniprot id: A0A0G3XDY1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

543877:AM2010 RS12580
gene id: 543877:AM2010_RS12580
uniprot id: A0A0G3XDX7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

543877:AM2010 RS05650
gene id: 543877:AM2010_RS05650
uniprot id: A0A0G3X7M1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

543877:AM2010 RS10980
gene id: 543877:AM2010_RS10980
uniprot id: A0A0G3XCY3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

543877:AM2010 RS03775
gene id: 543877:AM2010_RS03775
uniprot id: A0A0G3X876
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

543877:AM2010 RS09195
gene id: 543877:AM2010_RS09195
uniprot id: A0A0G3XB65
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

543877:AM2010 RS03875
gene id: 543877:AM2010_RS03875
uniprot id: A0A0G3X5Q4
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

543877:AM2010 RS13550
gene id: 543877:AM2010_RS13550
uniprot id: A0A0G3XDN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

543877:AM2010 RS01760
gene id: 543877:AM2010_RS01760
uniprot id: A0A0G3X4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

543877:AM2010 RS05130
gene id: 543877:AM2010_RS05130
uniprot id: A0A0G3X7E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

543877:AM2010 RS11665
gene id: 543877:AM2010_RS11665
uniprot id: A0A0G3XAZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS09660
gene id: 543877:AM2010_RS09660
uniprot id: A0A0G3X9U5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

543877:AM2010 RS04055
gene id: 543877:AM2010_RS04055
uniprot id: A0A0G3X6R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

543877:AM2010 RS02015
gene id: 543877:AM2010_RS02015
uniprot id: A0A0G3X5M2
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

543877:AM2010 RS10205
gene id: 543877:AM2010_RS10205
uniprot id: A0A0G3XCJ8
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

543877:AM2010 RS09620
gene id: 543877:AM2010_RS09620
uniprot id: A0A0G3X8S0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

543877:AM2010 RS10815
gene id: 543877:AM2010_RS10815
uniprot id: A0A0G3X9I8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

543877:AM2010 RS00575
gene id: 543877:AM2010_RS00575
uniprot id: A0A0G3X3V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

543877:AM2010 RS10105
gene id: 543877:AM2010_RS10105
uniprot id: A0A0G3XCI0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

543877:AM2010 RS02565
gene id: 543877:AM2010_RS02565
uniprot id: A0A0G3X7M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

543877:AM2010 RS02000
gene id: 543877:AM2010_RS02000
uniprot id: A0A0G3X793
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

543877:AM2010 RS06865
gene id: 543877:AM2010_RS06865
uniprot id: A0A0G3X9X2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

543877:AM2010 RS11225
gene id: 543877:AM2010_RS11225
uniprot id: A0A0G3XCC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

543877:AM2010 RS11675
gene id: 543877:AM2010_RS11675
uniprot id: A0A0G3XCP9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS03425
gene id: 543877:AM2010_RS03425
uniprot id: A0A0G3X5H0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

543877:AM2010 RS01140
gene id: 543877:AM2010_RS01140
uniprot id: A0A0G3X6T0
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

543877:AM2010 RS05290
gene id: 543877:AM2010_RS05290
uniprot id: A0A0G3X9V2
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

543877:AM2010 RS06990
gene id: 543877:AM2010_RS06990
uniprot id: A0A0G3X7A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

543877:AM2010 RS12280
gene id: 543877:AM2010_RS12280
uniprot id: A0A0G3XA93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

543877:AM2010 RS00690
gene id: 543877:AM2010_RS00690
uniprot id: A0A0G3X4Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

543877:AM2010 RS08410
gene id: 543877:AM2010_RS08410
uniprot id: A0A0G3XAS8
names: Similarity
messages: Belongs to the TPP enzyme family.

543877:AM2010 RS05785
gene id: 543877:AM2010_RS05785
uniprot id: A0A0G3X9D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

543877:AM2010 RS10440
gene id: 543877:AM2010_RS10440
uniprot id: A0A0G3XBX6
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

543877:AM2010 RS00250
gene id: 543877:AM2010_RS00250
uniprot id: A0A0G3X713
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS03145
gene id: 543877:AM2010_RS03145
uniprot id: A0A0G3X7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

543877:AM2010 RS12375
gene id: 543877:AM2010_RS12375
uniprot id: A0A0G3XD20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

543877:AM2010 RS07865
gene id: 543877:AM2010_RS07865
uniprot id: A0A0G3XAI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

543877:AM2010 RS11840
gene id: 543877:AM2010_RS11840
uniprot id: A0A0G3XDB4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS02040
gene id: 543877:AM2010_RS02040
uniprot id: A0A0G3X783
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

543877:AM2010 RS09030
gene id: 543877:AM2010_RS09030
uniprot id: A0A0G3XBR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

543877:AM2010 RS10795
gene id: 543877:AM2010_RS10795
uniprot id: A0A0G3XC42
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS02880
gene id: 543877:AM2010_RS02880
uniprot id: A0A0G3X629
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

543877:AM2010 RS12990
gene id: 543877:AM2010_RS12990
uniprot id: A0A0G3XE55
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS02175
gene id: 543877:AM2010_RS02175
uniprot id: A0A0G3X858
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

543877:AM2010 RS04445
gene id: 543877:AM2010_RS04445
uniprot id: A0A0G3X987
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS02545
gene id: 543877:AM2010_RS02545
uniprot id: A0A0G3X4X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

543877:AM2010 RS04665
gene id: 543877:AM2010_RS04665
uniprot id: A0A0G3X735
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

543877:AM2010 RS02945
gene id: 543877:AM2010_RS02945
uniprot id: A0A0G3X565
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

543877:AM2010 RS10515
gene id: 543877:AM2010_RS10515
uniprot id: A0A0G3X9E0
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

543877:AM2010 RS01355
gene id: 543877:AM2010_RS01355
uniprot id: A0A0G3X584
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

543877:AM2010 RS02995
gene id: 543877:AM2010_RS02995
uniprot id: A0A0G3X7V8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

543877:AM2010 RS00030
gene id: 543877:AM2010_RS00030
uniprot id: A0A0G3X4J8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

543877:AM2010 RS00035
gene id: 543877:AM2010_RS00035
uniprot id: A0A0G3X6X8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

543877:AM2010 RS07580
gene id: 543877:AM2010_RS07580
uniprot id: A0A0G3X7R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

543877:AM2010 RS02610
gene id: 543877:AM2010_RS02610
uniprot id: A0A0G3X8D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

543877:AM2010 RS07870
gene id: 543877:AM2010_RS07870
uniprot id: A0A0G3X8W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

543877:AM2010 RS05125
gene id: 543877:AM2010_RS05125
uniprot id: A0A0G3X902
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

543877:AM2010 RS02785
gene id: 543877:AM2010_RS02785
uniprot id: A0A0G3X7R9
names: Similarity
messages: Belongs to the CFA/CMAS family.

543877:AM2010 RS09235
gene id: 543877:AM2010_RS09235
uniprot id: A0A0G3X8K8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

543877:AM2010 RS05140
gene id: 543877:AM2010_RS05140
uniprot id: A0A0G3X912
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

543877:AM2010 RS11540
gene id: 543877:AM2010_RS11540
uniprot id: A0A0G3XD62
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

543877:AM2010 RS06320
gene id: 543877:AM2010_RS06320
uniprot id: A0A0G3XAA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

543877:AM2010 RS05020
gene id: 543877:AM2010_RS05020
uniprot id: A0A0G3X6B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

543877:AM2010 RS06550
gene id: 543877:AM2010_RS06550
uniprot id: A0A0G3X837
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

543877:AM2010 RS01380
gene id: 543877:AM2010_RS01380
uniprot id: A0A0G3X587
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

543877:AM2010 RS06490
gene id: 543877:AM2010_RS06490
uniprot id: A0A0G3X726
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

543877:AM2010 RS12795
gene id: 543877:AM2010_RS12795
uniprot id: A0A0G3XAP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

543877:AM2010 RS12585
gene id: 543877:AM2010_RS12585
uniprot id: A0A0G3XD99
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

543877:AM2010 RS04915
gene id: 543877:AM2010_RS04915
uniprot id: A0A0G3X8X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

543877:AM2010 RS06775
gene id: 543877:AM2010_RS06775
uniprot id: A0A0G3XAI3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

543877:AM2010 RS01260
gene id: 543877:AM2010_RS01260
uniprot id: A0A0G3X6V4
names: Similarity
messages: Belongs to the YkuD family.

543877:AM2010 RS10630
gene id: 543877:AM2010_RS10630
uniprot id: A0A0G3XC54
names: Similarity
messages: Belongs to the phosphohexose mutase family.

543877:AM2010 RS10710
gene id: 543877:AM2010_RS10710
uniprot id: A0A0G3XC70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

543877:AM2010 RS03160
gene id: 543877:AM2010_RS03160
uniprot id: A0A0G3X671
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

543877:AM2010 RS12390
gene id: 543877:AM2010_RS12390
uniprot id: A0A0G3XBE8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

543877:AM2010 RS02190
gene id: 543877:AM2010_RS02190
uniprot id: A0A0G3X7F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

543877:AM2010 RS04200
gene id: 543877:AM2010_RS04200
uniprot id: A0A0G3X5V0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

543877:AM2010 RS00330
gene id: 543877:AM2010_RS00330
uniprot id: A0A0G3X3R5
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS08460
gene id: 543877:AM2010_RS08460
uniprot id: A0A0G3XAV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

543877:AM2010 RS05665
gene id: 543877:AM2010_RS05665
uniprot id: A0A0G3X6M3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

543877:AM2010 RS12930
gene id: 543877:AM2010_RS12930
uniprot id: A0A0G3XDB7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543877:AM2010 RS04040
gene id: 543877:AM2010_RS04040
uniprot id: A0A0G3X8D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

543877:AM2010 RS07785
gene id: 543877:AM2010_RS07785
uniprot id: A0A0G3XAG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

543877:AM2010 RS09125
gene id: 543877:AM2010_RS09125
uniprot id: A0A0G3XB51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

543877:AM2010 RS07950
gene id: 543877:AM2010_RS07950
uniprot id: A0A0G3XBB2
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS02710
gene id: 543877:AM2010_RS02710
uniprot id: A0A0G3X8F6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

543877:AM2010 RS08710
gene id: 543877:AM2010_RS08710
uniprot id: A0A0G3X8B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

543877:AM2010 RS12245
gene id: 543877:AM2010_RS12245
uniprot id: A0A0G3XD00
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

543877:AM2010 RS13085
gene id: 543877:AM2010_RS13085
uniprot id: A0A0G3XBU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

543877:AM2010 RS07130
gene id: 543877:AM2010_RS07130
uniprot id: A0A0G3XA37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

543877:AM2010 RS06375
gene id: 543877:AM2010_RS06375
uniprot id: A0A0G3XAB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

543877:AM2010 RS09980
gene id: 543877:AM2010_RS09980
uniprot id: A0A0G3XA54
names: Similarity
messages: Belongs to the pyruvate kinase family.

543877:AM2010 RS11345
gene id: 543877:AM2010_RS11345
uniprot id: A0A0G3X9T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

543877:AM2010 RS09670
gene id: 543877:AM2010_RS09670
uniprot id: A0A0G3XBI6
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

543877:AM2010 RS03290
gene id: 543877:AM2010_RS03290
uniprot id: A0A0G3X6C9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

543877:AM2010 RS08985
gene id: 543877:AM2010_RS08985
uniprot id: A0A0G3XBR0
names: Subcellular Location Annotation
messages: Membrane

543877:AM2010 RS03085
gene id: 543877:AM2010_RS03085
uniprot id: A0A0G3X659
names: Similarity
messages: Belongs to the AHA1 family.

543877:AM2010 RS10810
gene id: 543877:AM2010_RS10810
uniprot id: A0A0G3XC90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

543877:AM2010 RS05375
gene id: 543877:AM2010_RS05375
uniprot id: A0A0G3X9W6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

543877:AM2010 RS02810
gene id: 543877:AM2010_RS02810
uniprot id: A0A0G3X7S4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

543877:AM2010 RS04265
gene id: 543877:AM2010_RS04265
uniprot id: A0A0G3X6V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

543877:AM2010 RS04345
gene id: 543877:AM2010_RS04345
uniprot id: A0A0G3X964
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

543877:AM2010 RS10605
gene id: 543877:AM2010_RS10605
uniprot id: A0A0G3XC49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

543877:AM2010 RS02230
gene id: 543877:AM2010_RS02230
uniprot id: A0A0G3X7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

543877:AM2010 RS07980
gene id: 543877:AM2010_RS07980
uniprot id: A0A0G3XAM3
names: Similarity
messages: Belongs to the SufE family.

543877:AM2010 RS06220
gene id: 543877:AM2010_RS06220
uniprot id: A0A0G3X9L2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

543877:AM2010 RS02770
gene id: 543877:AM2010_RS02770
uniprot id: A0A0G3X7P9
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

543877:AM2010 RS01285
gene id: 543877:AM2010_RS01285
uniprot id: A0A0G3X6V8
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

543877:AM2010 RS00350
gene id: 543877:AM2010_RS00350
uniprot id: A0A0G3X6E1
names: Subcellular Location Annotation
messages: Cytoplasm

543877:AM2010 RS09175
gene id: 543877:AM2010_RS09175
uniprot id: A0A0G3X9J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

543877:AM2010 RS06495
gene id: 543877:AM2010_RS06495
uniprot id: A0A0G3X9P7
names: Similarity
messages: Belongs to the citrate synthase family.

543877:AM2010 RS02105
gene id: 543877:AM2010_RS02105
uniprot id: A0A0G3X7B0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

543877:AM2010 RS10025
gene id: 543877:AM2010_RS10025
uniprot id: A0A0G3XA60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

543877:AM2010 RS11920
gene id: 543877:AM2010_RS11920
uniprot id: A0A0G3XA36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.