52774:EL266 RS07910
gene id: 52774:EL266_RS07910
uniprot id: A0A448KDE0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

52774:EL266 RS06365
gene id: 52774:EL266_RS06365
uniprot id: A0A3S4UNJ5
names: Similarity
messages: Belongs to the hyi family.

52774:EL266 RS05955
gene id: 52774:EL266_RS05955
uniprot id: A0A3S4UNE3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52774:EL266 RS09850
gene id: 52774:EL266_RS09850
uniprot id: A0A3S4U348
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

52774:EL266 RS11120
gene id: 52774:EL266_RS11120
uniprot id: A0A448KF83
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS07040
gene id: 52774:EL266_RS07040
uniprot id: A0A448KCY4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

52774:EL266 RS06710
gene id: 52774:EL266_RS06710
uniprot id: A0A448KCR6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

52774:EL266 RS00685
gene id: 52774:EL266_RS00685
uniprot id: A0A3S4SRU2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

52774:EL266 RS01895
gene id: 52774:EL266_RS01895
uniprot id: A0A3S4TB24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS05310
gene id: 52774:EL266_RS05310
uniprot id: A0A3S4U1W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

52774:EL266 RS02265
gene id: 52774:EL266_RS02265
uniprot id: A0A448KA95
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

52774:EL266 RS05770
gene id: 52774:EL266_RS05770
uniprot id: A0A3S4ST85
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS05965
gene id: 52774:EL266_RS05965
uniprot id: A0A448KCB3
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

52774:EL266 RS06165
gene id: 52774:EL266_RS06165
uniprot id: A0A3S4SP78
names: Similarity
messages: Belongs to the LOG family.

52774:EL266 RS10800
gene id: 52774:EL266_RS10800
uniprot id: A0A3S5EMB6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

52774:EL266 RS06155
gene id: 52774:EL266_RS06155
uniprot id: A0A3S5EM69
names: Similarity
messages: Belongs to the phosphohexose mutase family.

52774:EL266 RS13315
gene id: 52774:EL266_RS13315
uniprot id: A0A3S4SVB5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

52774:EL266 RS07345
gene id: 52774:EL266_RS07345
uniprot id: A0A3S4STQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS00575
gene id: 52774:EL266_RS00575
uniprot id: A0A448K966
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS11240
gene id: 52774:EL266_RS11240
uniprot id: A0A3S4U3G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

52774:EL266 RS05005
gene id: 52774:EL266_RS05005
uniprot id: A0A3S4WJN2
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

52774:EL266 RS11300
gene id: 52774:EL266_RS11300
uniprot id: A0A448KF75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

52774:EL266 RS02480
gene id: 52774:EL266_RS02480
uniprot id: A0A3S4SDY8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

52774:EL266 RS07115
gene id: 52774:EL266_RS07115
uniprot id: A0A3S4STN4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

52774:EL266 RS07515
gene id: 52774:EL266_RS07515
uniprot id: A0A3S4WH94
names: Similarity
messages: Belongs to the GcvT family.

52774:EL266 RS06735
gene id: 52774:EL266_RS06735
uniprot id: A0A3S4STJ7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

52774:EL266 RS03045
gene id: 52774:EL266_RS03045
uniprot id: A0A3S4SSI7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

52774:EL266 RS05845
gene id: 52774:EL266_RS05845
uniprot id: A0A448KC94
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

52774:EL266 RS09925
gene id: 52774:EL266_RS09925
uniprot id: A0A448KEG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

52774:EL266 RS01190
gene id: 52774:EL266_RS01190
uniprot id: A0A448K9J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

52774:EL266 RS05945
gene id: 52774:EL266_RS05945
uniprot id: A0A3S4U218
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

52774:EL266 RS09745
gene id: 52774:EL266_RS09745
uniprot id: A0A448KEC0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

52774:EL266 RS01430
gene id: 52774:EL266_RS01430
uniprot id: A0A448K9Q6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

52774:EL266 RS00260
gene id: 52774:EL266_RS00260
uniprot id: A0A448K8Z9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

52774:EL266 RS12355
gene id: 52774:EL266_RS12355
uniprot id: A0A448KFS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

52774:EL266 RS02630
gene id: 52774:EL266_RS02630
uniprot id: A0A448KAG8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

52774:EL266 RS11740
gene id: 52774:EL266_RS11740
uniprot id: A0A448KFM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

52774:EL266 RS01505
gene id: 52774:EL266_RS01505
uniprot id: A0A448K9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

52774:EL266 RS02460
gene id: 52774:EL266_RS02460
uniprot id: A0A448KAC2
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS10460
gene id: 52774:EL266_RS10460
uniprot id: A0A3S4WI29
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

52774:EL266 RS06745
gene id: 52774:EL266_RS06745
uniprot id: A0A448KCW7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

52774:EL266 RS00675
gene id: 52774:EL266_RS00675
uniprot id: A0A448K990
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52774:EL266 RS09655
gene id: 52774:EL266_RS09655
uniprot id: A0A3S4SQD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

52774:EL266 RS01870
gene id: 52774:EL266_RS01870
uniprot id: A0A448KA11
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

52774:EL266 RS01960
gene id: 52774:EL266_RS01960
uniprot id: A0A448KA33
names: Similarity
messages: Belongs to the fructosamine kinase family.

52774:EL266 RS08810
gene id: 52774:EL266_RS08810
uniprot id: A0A3S4WKW4
names: Similarity
messages: Belongs to the glutamate synthase family.

52774:EL266 RS00825
gene id: 52774:EL266_RS00825
uniprot id: A0A448K9D4
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS06235
gene id: 52774:EL266_RS06235
uniprot id: A0A448KCK9
names: Similarity
messages: Belongs to the DEAD box helicase family.

52774:EL266 RS12490
gene id: 52774:EL266_RS12490
uniprot id: A0A448KG01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

52774:EL266 RS06005
gene id: 52774:EL266_RS06005
uniprot id: A0A3S4SK47
names: Similarity
messages: Belongs to the GSP E family.

52774:EL266 RS00335
gene id: 52774:EL266_RS00335
uniprot id: A0A448K959
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

52774:EL266 RS09575
gene id: 52774:EL266_RS09575
uniprot id: A0A3S4SQC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

52774:EL266 RS07500
gene id: 52774:EL266_RS07500
uniprot id: A0A448KD54
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

52774:EL266 RS00115
gene id: 52774:EL266_RS00115
uniprot id: A0A3S4WI69
names: Similarity
messages: Belongs to the BioY family.

52774:EL266 RS04660
gene id: 52774:EL266_RS04660
uniprot id: A0A3S4UMZ5
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

52774:EL266 RS13020
gene id: 52774:EL266_RS13020
uniprot id: A0A3S4SRD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

52774:EL266 RS00925
gene id: 52774:EL266_RS00925
uniprot id: A0A3S4TAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS05330
gene id: 52774:EL266_RS05330
uniprot id: A0A448KBX9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

52774:EL266 RS00265
gene id: 52774:EL266_RS00265
uniprot id: A0A3S4SDC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

52774:EL266 RS13015
gene id: 52774:EL266_RS13015
uniprot id: A0A3S5EMD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

52774:EL266 RS09085
gene id: 52774:EL266_RS09085
uniprot id: A0A3S4UPC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

52774:EL266 RS02155
gene id: 52774:EL266_RS02155
uniprot id: A0A3S4SDW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

52774:EL266 RS08795
gene id: 52774:EL266_RS08795
uniprot id: A0A3S4TD38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

52774:EL266 RS05300
gene id: 52774:EL266_RS05300
uniprot id: A0A448KC18
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

52774:EL266 RS03915
gene id: 52774:EL266_RS03915
uniprot id: A0A3S4WJB8
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS01165
gene id: 52774:EL266_RS01165
uniprot id: A0A3S4SRY1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

52774:EL266 RS09420
gene id: 52774:EL266_RS09420
uniprot id: A0A448KEA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

52774:EL266 RS09810
gene id: 52774:EL266_RS09810
uniprot id: A0A3S4WL70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

52774:EL266 RS05525
gene id: 52774:EL266_RS05525
uniprot id: A0A448KC22
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

52774:EL266 RS05190
gene id: 52774:EL266_RS05190
uniprot id: A0A448KBV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

52774:EL266 RS12360
gene id: 52774:EL266_RS12360
uniprot id: A0A448KFW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS11640
gene id: 52774:EL266_RS11640
uniprot id: A0A448KFI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS13265
gene id: 52774:EL266_RS13265
uniprot id: A0A448KGA9
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

52774:EL266 RS09750
gene id: 52774:EL266_RS09750
uniprot id: A0A3S4WHV8
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

52774:EL266 RS12195
gene id: 52774:EL266_RS12195
uniprot id: A0A448KFP8
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

52774:EL266 RS06250
gene id: 52774:EL266_RS06250
uniprot id: A0A3S4SK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

52774:EL266 RS08020
gene id: 52774:EL266_RS08020
uniprot id: A0A3S4SPT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

52774:EL266 RS07085
gene id: 52774:EL266_RS07085
uniprot id: A0A3S4SKG0
names: Similarity
messages: Belongs to the peptidase M13 family.

52774:EL266 RS05815
gene id: 52774:EL266_RS05815
uniprot id: A0A448KC82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane

52774:EL266 RS12180
gene id: 52774:EL266_RS12180
uniprot id: A0A3S4SV04
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

52774:EL266 RS00750
gene id: 52774:EL266_RS00750
uniprot id: A0A448K9F2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

52774:EL266 RS08610
gene id: 52774:EL266_RS08610
uniprot id: A0A448KDR7
names: Similarity
messages: Belongs to the UPF0098 family.

52774:EL266 RS13030
gene id: 52774:EL266_RS13030
uniprot id: A0A3S4SM06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

52774:EL266 RS05230
gene id: 52774:EL266_RS05230
uniprot id: A0A448KBV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

52774:EL266 RS07425
gene id: 52774:EL266_RS07425
uniprot id: A0A3S4SKJ1
names: Function
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.

52774:EL266 RS10180
gene id: 52774:EL266_RS10180
uniprot id: A0A3S4WHZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

52774:EL266 RS05140
gene id: 52774:EL266_RS05140
uniprot id: A0A448KBU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

52774:EL266 RS05185
gene id: 52774:EL266_RS05185
uniprot id: A0A3S4UN49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

52774:EL266 RS01050
gene id: 52774:EL266_RS01050
uniprot id: A0A448K9L4
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

52774:EL266 RS13040
gene id: 52774:EL266_RS13040
uniprot id: A0A3S4U3Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

52774:EL266 RS01525
gene id: 52774:EL266_RS01525
uniprot id: A0A448K9N1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS11100
gene id: 52774:EL266_RS11100
uniprot id: A0A3S4TDQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

52774:EL266 RS11340
gene id: 52774:EL266_RS11340
uniprot id: A0A448KFC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

52774:EL266 RS00850
gene id: 52774:EL266_RS00850
uniprot id: A0A3S4SIR9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

52774:EL266 RS08350
gene id: 52774:EL266_RS08350
uniprot id: A0A3S4WHH9
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS12985
gene id: 52774:EL266_RS12985
uniprot id: A0A448KG83
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

52774:EL266 RS01520
gene id: 52774:EL266_RS01520
uniprot id: A0A448K9V6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

52774:EL266 RS04350
gene id: 52774:EL266_RS04350
uniprot id: A0A3S4WGA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

52774:EL266 RS04220
gene id: 52774:EL266_RS04220
uniprot id: A0A448KBB0
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

52774:EL266 RS00080
gene id: 52774:EL266_RS00080
uniprot id: A0A448K8X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

52774:EL266 RS06940
gene id: 52774:EL266_RS06940
uniprot id: A0A3S5EM78
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

52774:EL266 RS10175
gene id: 52774:EL266_RS10175
uniprot id: A0A448KEP6
names: Similarity
messages: Belongs to the glutamine synthetase family.

52774:EL266 RS07505
gene id: 52774:EL266_RS07505
uniprot id: A0A3S4SPM7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

52774:EL266 RS03815
gene id: 52774:EL266_RS03815
uniprot id: A0A3S4WJA7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

52774:EL266 RS10070
gene id: 52774:EL266_RS10070
uniprot id: A0A3S4SL96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

52774:EL266 RS09065
gene id: 52774:EL266_RS09065
uniprot id: A0A448KE39
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

52774:EL266 RS09020
gene id: 52774:EL266_RS09020
uniprot id: A0A448KE10
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

52774:EL266 RS02695
gene id: 52774:EL266_RS02695
uniprot id: A0A3S4WIY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

52774:EL266 RS04525
gene id: 52774:EL266_RS04525
uniprot id: A0A3S4SNQ1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52774:EL266 RS07675
gene id: 52774:EL266_RS07675
uniprot id: A0A448KDD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

52774:EL266 RS05490
gene id: 52774:EL266_RS05490
uniprot id: A0A3S4U1Y5
names: Similarity
messages: Belongs to the glycosyl hydrolase.

52774:EL266 RS06100
gene id: 52774:EL266_RS06100
uniprot id: A0A448KCD5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

52774:EL266 RS06730
gene id: 52774:EL266_RS06730
uniprot id: A0A448KCR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

52774:EL266 RS10780
gene id: 52774:EL266_RS10780
uniprot id: A0A3S4SGI6
names: Similarity
messages: Belongs to the MEMO1 family.

52774:EL266 RS04435
gene id: 52774:EL266_RS04435
uniprot id: A0A448KBI0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

52774:EL266 RS11850
gene id: 52774:EL266_RS11850
uniprot id: A0A3S4WIF9
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS09000
gene id: 52774:EL266_RS09000
uniprot id: A0A448KE11
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS08575
gene id: 52774:EL266_RS08575
uniprot id: A0A448KDU4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

52774:EL266 RS09135
gene id: 52774:EL266_RS09135
uniprot id: A0A448KE22
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

52774:EL266 RS05610
gene id: 52774:EL266_RS05610
uniprot id: A0A448KC34
names: Similarity
messages: Belongs to the TPP enzyme family.

52774:EL266 RS01675
gene id: 52774:EL266_RS01675
uniprot id: A0A448K9Y1
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS11125
gene id: 52774:EL266_RS11125
uniprot id: A0A448KFA1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52774:EL266 RS05235
gene id: 52774:EL266_RS05235
uniprot id: A0A3S4SNV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

52774:EL266 RS00165
gene id: 52774:EL266_RS00165
uniprot id: A0A3S4U0E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

52774:EL266 RS03475
gene id: 52774:EL266_RS03475
uniprot id: A0A448KAZ4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

52774:EL266 RS06960
gene id: 52774:EL266_RS06960
uniprot id: A0A448KCY1
names: Similarity
messages: Belongs to the GSP E family.

52774:EL266 RS09805
gene id: 52774:EL266_RS09805
uniprot id: A0A3S4TDD1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

52774:EL266 RS04875
gene id: 52774:EL266_RS04875
uniprot id: A0A3S4SSZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

52774:EL266 RS07510
gene id: 52774:EL266_RS07510
uniprot id: A0A3S4SKK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

52774:EL266 RS06655
gene id: 52774:EL266_RS06655
uniprot id: A0A448KCR5
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS10410
gene id: 52774:EL266_RS10410
uniprot id: A0A3S4SGF6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

52774:EL266 RS04320
gene id: 52774:EL266_RS04320
uniprot id: A0A448KBE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

52774:EL266 RS09460
gene id: 52774:EL266_RS09460
uniprot id: A0A448KEE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

52774:EL266 RS12115
gene id: 52774:EL266_RS12115
uniprot id: A0A3S4TE02
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS12640
gene id: 52774:EL266_RS12640
uniprot id: A0A448KG31
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

52774:EL266 RS02960
gene id: 52774:EL266_RS02960
uniprot id: A0A448KAM1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

52774:EL266 RS07555
gene id: 52774:EL266_RS07555
uniprot id: A0A448KD72
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS08145
gene id: 52774:EL266_RS08145
uniprot id: A0A3S4SKR5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS10855
gene id: 52774:EL266_RS10855
uniprot id: A0A3S4UPV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

52774:EL266 RS02720
gene id: 52774:EL266_RS02720
uniprot id: A0A448KAI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

52774:EL266 RS12040
gene id: 52774:EL266_RS12040
uniprot id: A0A3S4WIH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

52774:EL266 RS09375
gene id: 52774:EL266_RS09375
uniprot id: A0A448KE82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

52774:EL266 RS12285
gene id: 52774:EL266_RS12285
uniprot id: A0A448KFW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

52774:EL266 RS00800
gene id: 52774:EL266_RS00800
uniprot id: A0A448K9G3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

52774:EL266 RS08885
gene id: 52774:EL266_RS08885
uniprot id: A0A448KDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

52774:EL266 RS06295
gene id: 52774:EL266_RS06295
uniprot id: A0A3S5EM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS03010
gene id: 52774:EL266_RS03010
uniprot id: A0A3S5EM36
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS12975
gene id: 52774:EL266_RS12975
uniprot id: A0A448KG39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

52774:EL266 RS04890
gene id: 52774:EL266_RS04890
uniprot id: A0A448KBN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

52774:EL266 RS02490
gene id: 52774:EL266_RS02490
uniprot id: A0A448KAE1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

52774:EL266 RS05390
gene id: 52774:EL266_RS05390
uniprot id: A0A3S5EM60
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

52774:EL266 RS05030
gene id: 52774:EL266_RS05030
uniprot id: A0A448KBS1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

52774:EL266 RS07630
gene id: 52774:EL266_RS07630
uniprot id: A0A3S4UNX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

52774:EL266 RS06440
gene id: 52774:EL266_RS06440
uniprot id: A0A3S4STF8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

52774:EL266 RS01500
gene id: 52774:EL266_RS01500
uniprot id: A0A448K9Q7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

52774:EL266 RS00455
gene id: 52774:EL266_RS00455
uniprot id: A0A3S4SMK7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS04975
gene id: 52774:EL266_RS04975
uniprot id: A0A3S4U1T3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

52774:EL266 RS03135
gene id: 52774:EL266_RS03135
uniprot id: A0A448KAR4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52774:EL266 RS13010
gene id: 52774:EL266_RS13010
uniprot id: A0A3S4WM28
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

52774:EL266 RS01455
gene id: 52774:EL266_RS01455
uniprot id: A0A448K9T6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

52774:EL266 RS09930
gene id: 52774:EL266_RS09930
uniprot id: A0A448KEJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

52774:EL266 RS05905
gene id: 52774:EL266_RS05905
uniprot id: A0A3S4SF21
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

52774:EL266 RS08630
gene id: 52774:EL266_RS08630
uniprot id: A0A3S4U2T2
names: Similarity
messages: Belongs to the thymidine kinase family.

52774:EL266 RS05650
gene id: 52774:EL266_RS05650
uniprot id: A0A448KC71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

52774:EL266 RS03690
gene id: 52774:EL266_RS03690
uniprot id: A0A3S5EM43
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

52774:EL266 RS01490
gene id: 52774:EL266_RS01490
uniprot id: A0A448K9P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

52774:EL266 RS10640
gene id: 52774:EL266_RS10640
uniprot id: A0A448KEX8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

52774:EL266 RS03060
gene id: 52774:EL266_RS03060
uniprot id: A0A3S4UMH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS08645
gene id: 52774:EL266_RS08645
uniprot id: A0A3S4UP77
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

52774:EL266 RS00790
gene id: 52774:EL266_RS00790
uniprot id: A0A448K9F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS00245
gene id: 52774:EL266_RS00245
uniprot id: A0A3S4U0E9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

52774:EL266 RS03605
gene id: 52774:EL266_RS03605
uniprot id: A0A3S4U1E7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

52774:EL266 RS08440
gene id: 52774:EL266_RS08440
uniprot id: A0A448KDQ2
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

52774:EL266 RS02705
gene id: 52774:EL266_RS02705
uniprot id: A0A3S4SN77
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

52774:EL266 RS08960
gene id: 52774:EL266_RS08960
uniprot id: A0A448KDY9
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS02585
gene id: 52774:EL266_RS02585
uniprot id: A0A448KAF6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

52774:EL266 RS01020
gene id: 52774:EL266_RS01020
uniprot id: A0A3S4TAW0
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS10105
gene id: 52774:EL266_RS10105
uniprot id: A0A448KEI7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

52774:EL266 RS03150
gene id: 52774:EL266_RS03150
uniprot id: A0A3S4WFT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

52774:EL266 RS11255
gene id: 52774:EL266_RS11255
uniprot id: A0A3S4SGN2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

52774:EL266 RS02215
gene id: 52774:EL266_RS02215
uniprot id: A0A448KA80
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

52774:EL266 RS08635
gene id: 52774:EL266_RS08635
uniprot id: A0A448KDY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

52774:EL266 RS13195
gene id: 52774:EL266_RS13195
uniprot id: A0A448KGE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS00425
gene id: 52774:EL266_RS00425
uniprot id: A0A3S4SDD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

52774:EL266 RS10530
gene id: 52774:EL266_RS10530
uniprot id: A0A448KEV8
names: Similarity
messages: Belongs to the TlyA family.

52774:EL266 RS05660
gene id: 52774:EL266_RS05660
uniprot id: A0A3S4U1Z9
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS00680
gene id: 52774:EL266_RS00680
uniprot id: A0A3S4U0K1
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS12290
gene id: 52774:EL266_RS12290
uniprot id: A0A3S4SR60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

52774:EL266 RS11475
gene id: 52774:EL266_RS11475
uniprot id: A0A3S5EMC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

52774:EL266 RS02770
gene id: 52774:EL266_RS02770
uniprot id: A0A448KAK4
names: Subcellular Location Annotation
messages: chloroplast

52774:EL266 RS05220
gene id: 52774:EL266_RS05220
uniprot id: A0A3S4WJQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

52774:EL266 RS06255
gene id: 52774:EL266_RS06255
uniprot id: A0A448KCH0
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.

52774:EL266 RS05515
gene id: 52774:EL266_RS05515
uniprot id: A0A3S4ST55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

52774:EL266 RS02210
gene id: 52774:EL266_RS02210
uniprot id: A0A3S4WFJ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS11160
gene id: 52774:EL266_RS11160
uniprot id: A0A3S4UPY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

52774:EL266 RS08220
gene id: 52774:EL266_RS08220
uniprot id: A0A3S4TCY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

52774:EL266 RS11595
gene id: 52774:EL266_RS11595
uniprot id: A0A448KFH7
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

52774:EL266 RS13280
gene id: 52774:EL266_RS13280
uniprot id: A0A3S4SRG4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS08035
gene id: 52774:EL266_RS08035
uniprot id: A0A448KDL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

52774:EL266 RS04860
gene id: 52774:EL266_RS04860
uniprot id: A0A448KBR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

52774:EL266 RS05200
gene id: 52774:EL266_RS05200
uniprot id: A0A3S4SEU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

52774:EL266 RS13305
gene id: 52774:EL266_RS13305
uniprot id: A0A3S4U427
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

52774:EL266 RS05305
gene id: 52774:EL266_RS05305
uniprot id: A0A3S4WGK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

52774:EL266 RS05780
gene id: 52774:EL266_RS05780
uniprot id: A0A3S4SF08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

52774:EL266 RS11315
gene id: 52774:EL266_RS11315
uniprot id: A0A3S4U3H3
names: Similarity
messages: Belongs to the UPF0102 family.

52774:EL266 RS03290
gene id: 52774:EL266_RS03290
uniprot id: A0A3S4TBE8
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

52774:EL266 RS06605
gene id: 52774:EL266_RS06605
uniprot id: A0A3S4WK72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

52774:EL266 RS06215
gene id: 52774:EL266_RS06215
uniprot id: A0A3S4TCC5
names: Similarity
messages: Belongs to the peptidase M24B family.

52774:EL266 RS09030
gene id: 52774:EL266_RS09030
uniprot id: A0A448KE01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

52774:EL266 RS08315
gene id: 52774:EL266_RS08315
uniprot id: A0A3S4WKR2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

52774:EL266 RS03115
gene id: 52774:EL266_RS03115
uniprot id: A0A448KAQ5
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS02565
gene id: 52774:EL266_RS02565
uniprot id: A0A448KAG7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

52774:EL266 RS02455
gene id: 52774:EL266_RS02455
uniprot id: A0A448KAC6
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

52774:EL266 RS13070
gene id: 52774:EL266_RS13070
uniprot id: A0A448KG62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

52774:EL266 RS07340
gene id: 52774:EL266_RS07340
uniprot id: A0A448KD20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS07655
gene id: 52774:EL266_RS07655
uniprot id: A0A3S4WKI8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

52774:EL266 RS04625
gene id: 52774:EL266_RS04625
uniprot id: A0A3S4SJQ9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

52774:EL266 RS10570
gene id: 52774:EL266_RS10570
uniprot id: A0A448KEW9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

52774:EL266 RS05550
gene id: 52774:EL266_RS05550
uniprot id: A0A448KC28
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS09675
gene id: 52774:EL266_RS09675
uniprot id: A0A3S4U328
names: Similarity
messages: Belongs to the creatininase superfamily.

52774:EL266 RS04655
gene id: 52774:EL266_RS04655
uniprot id: A0A3S4SSX8
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS00205
gene id: 52774:EL266_RS00205
uniprot id: A0A3S4WI79
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

52774:EL266 RS05405
gene id: 52774:EL266_RS05405
uniprot id: A0A448KBZ0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

52774:EL266 RS10520
gene id: 52774:EL266_RS10520
uniprot id: A0A448KEU8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

52774:EL266 RS00785
gene id: 52774:EL266_RS00785
uniprot id: A0A448K9B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS00720
gene id: 52774:EL266_RS00720
uniprot id: A0A448K986
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

52774:EL266 RS12685
gene id: 52774:EL266_RS12685
uniprot id: A0A448KG43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS00705
gene id: 52774:EL266_RS00705
uniprot id: A0A3S4SDG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

52774:EL266 RS07825
gene id: 52774:EL266_RS07825
uniprot id: A0A3S4STV7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

52774:EL266 RS10135
gene id: 52774:EL266_RS10135
uniprot id: A0A3S4SGC7
names: Similarity
messages: Belongs to the glutamine synthetase family.

52774:EL266 RS09015
gene id: 52774:EL266_RS09015
uniprot id: A0A3S4WKZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

52774:EL266 RS07455
gene id: 52774:EL266_RS07455
uniprot id: A0A448KD55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

52774:EL266 RS05450
gene id: 52774:EL266_RS05450
uniprot id: A0A3S4UN73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

52774:EL266 RS04510
gene id: 52774:EL266_RS04510
uniprot id: A0A448KBH0
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS00065
gene id: 52774:EL266_RS00065
uniprot id: A0A3S4WEZ5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

52774:EL266 RS09705
gene id: 52774:EL266_RS09705
uniprot id: A0A3S4SG85
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS01160
gene id: 52774:EL266_RS01160
uniprot id: A0A3S4U0Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

52774:EL266 RS12950
gene id: 52774:EL266_RS12950
uniprot id: A0A448KG95
names: Similarity
messages: Belongs to the UPF0234 family.

52774:EL266 RS09455
gene id: 52774:EL266_RS09455
uniprot id: A0A448KEA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS07810
gene id: 52774:EL266_RS07810
uniprot id: A0A3S4WHC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

52774:EL266 RS05940
gene id: 52774:EL266_RS05940
uniprot id: A0A3S4WGS5
names: Similarity
messages: Belongs to the acylphosphatase family.

52774:EL266 RS08555
gene id: 52774:EL266_RS08555
uniprot id: A0A3S4WHJ9
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

52774:EL266 RS03210
gene id: 52774:EL266_RS03210
uniprot id: A0A448KAT6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

52774:EL266 RS03955
gene id: 52774:EL266_RS03955
uniprot id: A0A448KB88
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

52774:EL266 RS12140
gene id: 52774:EL266_RS12140
uniprot id: A0A448KFP0
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS02095
gene id: 52774:EL266_RS02095
uniprot id: A0A448KA76
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

52774:EL266 RS11500
gene id: 52774:EL266_RS11500
uniprot id: A0A448KFB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

52774:EL266 RS02550
gene id: 52774:EL266_RS02550
uniprot id: A0A3S4U145
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

52774:EL266 RS05320
gene id: 52774:EL266_RS05320
uniprot id: A0A3S4ST33
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

52774:EL266 RS13160
gene id: 52774:EL266_RS13160
uniprot id: A0A3S5EME1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

52774:EL266 RS06150
gene id: 52774:EL266_RS06150
uniprot id: A0A3S4WK16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS07110
gene id: 52774:EL266_RS07110
uniprot id: A0A448KCZ2
names: Similarity
messages: Belongs to the IMPACT family.

52774:EL266 RS02445
gene id: 52774:EL266_RS02445
uniprot id: A0A3S4WFM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

52774:EL266 RS12500
gene id: 52774:EL266_RS12500
uniprot id: A0A448KFW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

52774:EL266 RS10625
gene id: 52774:EL266_RS10625
uniprot id: A0A448KEZ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

52774:EL266 RS10905
gene id: 52774:EL266_RS10905
uniprot id: A0A3S4SQQ6
names: Similarity
messages: Belongs to the YggT family.

52774:EL266 RS05930
gene id: 52774:EL266_RS05930
uniprot id: A0A3S4SK38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

52774:EL266 RS05925
gene id: 52774:EL266_RS05925
uniprot id: A0A3S4SP15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS06750
gene id: 52774:EL266_RS06750
uniprot id: A0A3S4SFC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

52774:EL266 RS06135
gene id: 52774:EL266_RS06135
uniprot id: A0A448KCJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

52774:EL266 RS09945
gene id: 52774:EL266_RS09945
uniprot id: A0A3S4TDF1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

52774:EL266 RS10470
gene id: 52774:EL266_RS10470
uniprot id: A0A3S4U3A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS05835
gene id: 52774:EL266_RS05835
uniprot id: A0A3S5EM65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

52774:EL266 RS04280
gene id: 52774:EL266_RS04280
uniprot id: A0A3S4SSU4
names: Similarity
messages: Belongs to the PspA/IM30 family.

52774:EL266 RS08710
gene id: 52774:EL266_RS08710
uniprot id: A0A3S4WKV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

52774:EL266 RS12375
gene id: 52774:EL266_RS12375
uniprot id: A0A448KFZ6
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS02500
gene id: 52774:EL266_RS02500
uniprot id: A0A3S4WIV9
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS09950
gene id: 52774:EL266_RS09950
uniprot id: A0A448KEJ7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

52774:EL266 RS10845
gene id: 52774:EL266_RS10845
uniprot id: A0A448KF29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

52774:EL266 RS07525
gene id: 52774:EL266_RS07525
uniprot id: A0A448KD60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

52774:EL266 RS04760
gene id: 52774:EL266_RS04760
uniprot id: A0A448KBN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

52774:EL266 RS07640
gene id: 52774:EL266_RS07640
uniprot id: A0A448KD83
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

52774:EL266 RS07805
gene id: 52774:EL266_RS07805
uniprot id: A0A448KDC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

52774:EL266 RS10705
gene id: 52774:EL266_RS10705
uniprot id: A0A3S4TDL3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

52774:EL266 RS07850
gene id: 52774:EL266_RS07850
uniprot id: A0A3S4SFP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

52774:EL266 RS08770
gene id: 52774:EL266_RS08770
uniprot id: A0A3S4U2U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

52774:EL266 RS10750
gene id: 52774:EL266_RS10750
uniprot id: A0A3S4WI46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

52774:EL266 RS10880
gene id: 52774:EL266_RS10880
uniprot id: A0A3S4TDN0
names: Subcellular Location Annotation
messages: Cytoplasm

52774:EL266 RS01885
gene id: 52774:EL266_RS01885
uniprot id: A0A448KA24
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

52774:EL266 RS02690
gene id: 52774:EL266_RS02690
uniprot id: A0A448KAH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

52774:EL266 RS05205
gene id: 52774:EL266_RS05205
uniprot id: A0A3S4TC05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

52774:EL266 RS00405
gene id: 52774:EL266_RS00405
uniprot id: A0A3S4U0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

52774:EL266 RS08855
gene id: 52774:EL266_RS08855
uniprot id: A0A3S4WHM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS11150
gene id: 52774:EL266_RS11150
uniprot id: A0A3S4U3F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

52774:EL266 RS01470
gene id: 52774:EL266_RS01470
uniprot id: A0A448K9V3
names: Similarity
messages: Belongs to the YciI family.

52774:EL266 RS12110
gene id: 52774:EL266_RS12110
uniprot id: A0A448KFV1
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS11840
gene id: 52774:EL266_RS11840
uniprot id: A0A3S4SR27
names: Similarity
messages: Belongs to the polysaccharide synthase family.

52774:EL266 RS05505
gene id: 52774:EL266_RS05505
uniprot id: A0A448KC45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

52774:EL266 RS08135
gene id: 52774:EL266_RS08135
uniprot id: A0A3S4SPU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

52774:EL266 RS02640
gene id: 52774:EL266_RS02640
uniprot id: A0A448KAG9
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS04325
gene id: 52774:EL266_RS04325
uniprot id: A0A448KBE3
names: Similarity
messages: Belongs to the peptidase C40 family.

52774:EL266 RS07070
gene id: 52774:EL266_RS07070
uniprot id: A0A3S4SPI2
names: Similarity
messages: Belongs to the peptidase M1 family.

52774:EL266 RS02670
gene id: 52774:EL266_RS02670
uniprot id: A0A448KAH5
names: Similarity
messages: Belongs to the ParB family.

52774:EL266 RS02980
gene id: 52774:EL266_RS02980
uniprot id: A0A3S4TBB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

52774:EL266 RS07250
gene id: 52774:EL266_RS07250
uniprot id: A0A3S4SFH3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

52774:EL266 RS12050
gene id: 52774:EL266_RS12050
uniprot id: A0A448KFK4
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

52774:EL266 RS05180
gene id: 52774:EL266_RS05180
uniprot id: A0A448KBU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

52774:EL266 RS01945
gene id: 52774:EL266_RS01945
uniprot id: A0A3S4SS91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

52774:EL266 RS05215
gene id: 52774:EL266_RS05215
uniprot id: A0A448KBV3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

52774:EL266 RS01410
gene id: 52774:EL266_RS01410
uniprot id: A0A3S4SMV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

52774:EL266 RS05800
gene id: 52774:EL266_RS05800
uniprot id: A0A3S4TC70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

52774:EL266 RS06470
gene id: 52774:EL266_RS06470
uniprot id: A0A448KCK6
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

52774:EL266 RS08085
gene id: 52774:EL266_RS08085
uniprot id: A0A3S4STX8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

52774:EL266 RS10320
gene id: 52774:EL266_RS10320
uniprot id: A0A3S4SGE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

52774:EL266 RS12870
gene id: 52774:EL266_RS12870
uniprot id: A0A3S4SRC4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

52774:EL266 RS12695
gene id: 52774:EL266_RS12695
uniprot id: A0A3S5EMD6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

52774:EL266 RS00100
gene id: 52774:EL266_RS00100
uniprot id: A0A3S4SDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS04050
gene id: 52774:EL266_RS04050
uniprot id: A0A3S4SSS9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

52774:EL266 RS08295
gene id: 52774:EL266_RS08295
uniprot id: A0A3S4SFU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

52774:EL266 RS08590
gene id: 52774:EL266_RS08590
uniprot id: A0A3S4WKU4
names: Similarity
messages: Belongs to the AHA1 family.

52774:EL266 RS00470
gene id: 52774:EL266_RS00470
uniprot id: A0A448K935
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

52774:EL266 RS09620
gene id: 52774:EL266_RS09620
uniprot id: A0A3S4SG74
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

52774:EL266 RS03625
gene id: 52774:EL266_RS03625
uniprot id: A0A448KB20
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

52774:EL266 RS13275
gene id: 52774:EL266_RS13275
uniprot id: A0A3S5EME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

52774:EL266 RS02950
gene id: 52774:EL266_RS02950
uniprot id: A0A3S4SSH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

52774:EL266 RS08365
gene id: 52774:EL266_RS08365
uniprot id: A0A448KDM1
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS05315
gene id: 52774:EL266_RS05315
uniprot id: A0A448KBX2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

52774:EL266 RS10050
gene id: 52774:EL266_RS10050
uniprot id: A0A3S5EMA9
names: Similarity
messages: Belongs to the FemABX family.

52774:EL266 RS07830
gene id: 52774:EL266_RS07830
uniprot id: A0A448KDC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

52774:EL266 RS07075
gene id: 52774:EL266_RS07075
uniprot id: A0A448KCX4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

52774:EL266 RS00840
gene id: 52774:EL266_RS00840
uniprot id: A0A3S4SMP3
names: Similarity
messages: Belongs to the cytochrome c-552 family.

52774:EL266 RS11275
gene id: 52774:EL266_RS11275
uniprot id: A0A448KFB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

52774:EL266 RS08100
gene id: 52774:EL266_RS08100
uniprot id: A0A3S4SFR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

52774:EL266 RS00460
gene id: 52774:EL266_RS00460
uniprot id: A0A3S4SIN5
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS00885
gene id: 52774:EL266_RS00885
uniprot id: A0A448K9D1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

52774:EL266 RS12770
gene id: 52774:EL266_RS12770
uniprot id: A0A3S4TE64
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

52774:EL266 RS10560
gene id: 52774:EL266_RS10560
uniprot id: A0A448KEX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

52774:EL266 RS07490
gene id: 52774:EL266_RS07490
uniprot id: A0A3S4WKG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS10330
gene id: 52774:EL266_RS10330
uniprot id: A0A448KER4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

52774:EL266 RS05470
gene id: 52774:EL266_RS05470
uniprot id: A0A3S4SNX0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

52774:EL266 RS05865
gene id: 52774:EL266_RS05865
uniprot id: A0A3S4SK28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS05240
gene id: 52774:EL266_RS05240
uniprot id: A0A448KBW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

52774:EL266 RS03485
gene id: 52774:EL266_RS03485
uniprot id: A0A448KAY2
names: Similarity
messages: Belongs to the RutC family.

52774:EL266 RS11470
gene id: 52774:EL266_RS11470
uniprot id: A0A448KFH0
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS09485
gene id: 52774:EL266_RS09485
uniprot id: A0A3S5EMA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

52774:EL266 RS04805
gene id: 52774:EL266_RS04805
uniprot id: A0A3S5EM55
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

52774:EL266 RS12395
gene id: 52774:EL266_RS12395
uniprot id: A0A3S4SLV4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

52774:EL266 RS10080
gene id: 52774:EL266_RS10080
uniprot id: A0A448KEN7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS12010
gene id: 52774:EL266_RS12010
uniprot id: A0A448KFP5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

52774:EL266 RS05255
gene id: 52774:EL266_RS05255
uniprot id: A0A448KBW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

52774:EL266 RS06425
gene id: 52774:EL266_RS06425
uniprot id: A0A3S4WGY0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

52774:EL266 RS04365
gene id: 52774:EL266_RS04365
uniprot id: A0A3S4U1M1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

52774:EL266 RS12510
gene id: 52774:EL266_RS12510
uniprot id: A0A448KFZ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

52774:EL266 RS05455
gene id: 52774:EL266_RS05455
uniprot id: A0A3S4SEW6
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

52774:EL266 RS07460
gene id: 52774:EL266_RS07460
uniprot id: A0A448KD39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

52774:EL266 RS11065
gene id: 52774:EL266_RS11065
uniprot id: A0A3S4WI77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

52774:EL266 RS10775
gene id: 52774:EL266_RS10775
uniprot id: A0A448KF22
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

52774:EL266 RS06350
gene id: 52774:EL266_RS06350
uniprot id: A0A448KCJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS09630
gene id: 52774:EL266_RS09630
uniprot id: A0A448KEA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

52774:EL266 RS06925
gene id: 52774:EL266_RS06925
uniprot id: A0A3S4TCK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: In the N-terminal section; belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

52774:EL266 RS01275
gene id: 52774:EL266_RS01275
uniprot id: A0A3S4SRY9
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS10990
gene id: 52774:EL266_RS10990
uniprot id: A0A3S4TDN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

52774:EL266 RS11560
gene id: 52774:EL266_RS11560
uniprot id: A0A3S4SGR2
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

52774:EL266 RS11665
gene id: 52774:EL266_RS11665
uniprot id: A0A448KFG0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS05150
gene id: 52774:EL266_RS05150
uniprot id: A0A448KBY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

52774:EL266 RS02470
gene id: 52774:EL266_RS02470
uniprot id: A0A3S4UMA8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

52774:EL266 RS02655
gene id: 52774:EL266_RS02655
uniprot id: A0A3S4SSF0
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

52774:EL266 RS04480
gene id: 52774:EL266_RS04480
uniprot id: A0A3S4UMX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

52774:EL266 RS05805
gene id: 52774:EL266_RS05805
uniprot id: A0A448KC77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

52774:EL266 RS00820
gene id: 52774:EL266_RS00820
uniprot id: A0A3S4WIE5
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS02800
gene id: 52774:EL266_RS02800
uniprot id: A0A3S4SE22
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS11570
gene id: 52774:EL266_RS11570
uniprot id: A0A448KFB5
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

52774:EL266 RS02795
gene id: 52774:EL266_RS02795
uniprot id: A0A448KAJ9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

52774:EL266 RS08820
gene id: 52774:EL266_RS08820
uniprot id: A0A448KDW4
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

52774:EL266 RS00035
gene id: 52774:EL266_RS00035
uniprot id: A0A448K8Z6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

52774:EL266 RS11875
gene id: 52774:EL266_RS11875
uniprot id: A0A448KFJ4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

52774:EL266 RS05510
gene id: 52774:EL266_RS05510
uniprot id: A0A448KC13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

52774:EL266 RS07215
gene id: 52774:EL266_RS07215
uniprot id: A0A448KCZ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS11845
gene id: 52774:EL266_RS11845
uniprot id: A0A3S4SLR1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

52774:EL266 RS00380
gene id: 52774:EL266_RS00380
uniprot id: A0A448K934
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

52774:EL266 RS02710
gene id: 52774:EL266_RS02710
uniprot id: A0A448KAK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

52774:EL266 RS11370
gene id: 52774:EL266_RS11370
uniprot id: A0A3S5EMC2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

52774:EL266 RS11330
gene id: 52774:EL266_RS11330
uniprot id: A0A448KFE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

52774:EL266 RS09075
gene id: 52774:EL266_RS09075
uniprot id: A0A3S4U2X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

52774:EL266 RS09660
gene id: 52774:EL266_RS09660
uniprot id: A0A448KEI3
names: Similarity
messages: Belongs to the carbamate kinase family.

52774:EL266 RS06965
gene id: 52774:EL266_RS06965
uniprot id: A0A448KCW1
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS11670
gene id: 52774:EL266_RS11670
uniprot id: A0A3S4SR09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

52774:EL266 RS10910
gene id: 52774:EL266_RS10910
uniprot id: A0A448KF51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

52774:EL266 RS07660
gene id: 52774:EL266_RS07660
uniprot id: A0A3S5EM85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

52774:EL266 RS00250
gene id: 52774:EL266_RS00250
uniprot id: A0A3S4SRQ5
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

52774:EL266 RS08665
gene id: 52774:EL266_RS08665
uniprot id: A0A448KDS8
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS11635
gene id: 52774:EL266_RS11635
uniprot id: A0A3S4SGS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS01465
gene id: 52774:EL266_RS01465
uniprot id: A0A448K9S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane

52774:EL266 RS06300
gene id: 52774:EL266_RS06300
uniprot id: A0A448KCG8
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

52774:EL266 RS01100
gene id: 52774:EL266_RS01100
uniprot id: A0A448K9H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

52774:EL266 RS01905
gene id: 52774:EL266_RS01905
uniprot id: A0A3S5EM25
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

52774:EL266 RS01070
gene id: 52774:EL266_RS01070
uniprot id: A0A3S4WF92
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

52774:EL266 RS00325
gene id: 52774:EL266_RS00325
uniprot id: A0A3S4SRR3
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

52774:EL266 RS06485
gene id: 52774:EL266_RS06485
uniprot id: A0A3S4TCF6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS05950
gene id: 52774:EL266_RS05950
uniprot id: A0A3S4STA7
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS12850
gene id: 52774:EL266_RS12850
uniprot id: A0A3S4SH52
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

52774:EL266 RS07715
gene id: 52774:EL266_RS07715
uniprot id: A0A448KDB0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

52774:EL266 RS11335
gene id: 52774:EL266_RS11335
uniprot id: A0A3S4UQ04
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

52774:EL266 RS11510
gene id: 52774:EL266_RS11510
uniprot id: A0A448KFD0
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS07665
gene id: 52774:EL266_RS07665
uniprot id: A0A448KD90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS09100
gene id: 52774:EL266_RS09100
uniprot id: A0A448KE34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS01815
gene id: 52774:EL266_RS01815
uniprot id: A0A448KA00
names: Similarity
messages: Belongs to the UPF0145 family.

52774:EL266 RS05790
gene id: 52774:EL266_RS05790
uniprot id: A0A448KCC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

52774:EL266 RS13080
gene id: 52774:EL266_RS13080
uniprot id: A0A3S4TE90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

52774:EL266 RS05340
gene id: 52774:EL266_RS05340
uniprot id: A0A448KBY6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS10950
gene id: 52774:EL266_RS10950
uniprot id: A0A3S4U3D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

52774:EL266 RS00445
gene id: 52774:EL266_RS00445
uniprot id: A0A448K931
names: Similarity
messages: Belongs to the PRORSD1 family.

52774:EL266 RS12385
gene id: 52774:EL266_RS12385
uniprot id: A0A3S5EMD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

52774:EL266 RS06525
gene id: 52774:EL266_RS06525
uniprot id: A0A3S4SPB6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

52774:EL266 RS11860
gene id: 52774:EL266_RS11860
uniprot id: A0A448KFN8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

52774:EL266 RS07495
gene id: 52774:EL266_RS07495
uniprot id: A0A3S5EM83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS12865
gene id: 52774:EL266_RS12865
uniprot id: A0A3S5EMD8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

52774:EL266 RS13170
gene id: 52774:EL266_RS13170
uniprot id: A0A448KG84
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS13065
gene id: 52774:EL266_RS13065
uniprot id: A0A448KGB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

52774:EL266 RS05350
gene id: 52774:EL266_RS05350
uniprot id: A0A448KC29
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

52774:EL266 RS10600
gene id: 52774:EL266_RS10600
uniprot id: A0A448KES9
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS10375
gene id: 52774:EL266_RS10375
uniprot id: A0A448KEP4
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS02715
gene id: 52774:EL266_RS02715
uniprot id: A0A448KAJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

52774:EL266 RS00855
gene id: 52774:EL266_RS00855
uniprot id: A0A3S4WF76
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

52774:EL266 RS01920
gene id: 52774:EL266_RS01920
uniprot id: A0A3S4SJ04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

52774:EL266 RS02645
gene id: 52774:EL266_RS02645
uniprot id: A0A3S4WFN7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

52774:EL266 RS11325
gene id: 52774:EL266_RS11325
uniprot id: A0A3S4SUT9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

52774:EL266 RS07130
gene id: 52774:EL266_RS07130
uniprot id: A0A448KCZ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

52774:EL266 RS04385
gene id: 52774:EL266_RS04385
uniprot id: A0A448KBF7
names: Similarity
messages: Belongs to the DapA family.

52774:EL266 RS12005
gene id: 52774:EL266_RS12005
uniprot id: A0A3S4WLT2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

52774:EL266 RS00625
gene id: 52774:EL266_RS00625
uniprot id: A0A448K977
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

52774:EL266 RS10290
gene id: 52774:EL266_RS10290
uniprot id: A0A448KEU4
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

52774:EL266 RS11880
gene id: 52774:EL266_RS11880
uniprot id: A0A3S4SGV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

52774:EL266 RS10370
gene id: 52774:EL266_RS10370
uniprot id: A0A3S4WI18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

52774:EL266 RS05360
gene id: 52774:EL266_RS05360
uniprot id: A0A448KC14
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

52774:EL266 RS05250
gene id: 52774:EL266_RS05250
uniprot id: A0A448KC04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

52774:EL266 RS06815
gene id: 52774:EL266_RS06815
uniprot id: A0A3S5EM77
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

52774:EL266 RS11165
gene id: 52774:EL266_RS11165
uniprot id: A0A3S4SGM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

52774:EL266 RS09940
gene id: 52774:EL266_RS09940
uniprot id: A0A3S4SGB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

52774:EL266 RS08225
gene id: 52774:EL266_RS08225
uniprot id: A0A3S4WKQ1
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS04995
gene id: 52774:EL266_RS04995
uniprot id: A0A3S4UN28
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS05265
gene id: 52774:EL266_RS05265
uniprot id: A0A448KBW2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

52774:EL266 RS02440
gene id: 52774:EL266_RS02440
uniprot id: A0A448KAC5
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS09115
gene id: 52774:EL266_RS09115
uniprot id: A0A448KE49
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

52774:EL266 RS09005
gene id: 52774:EL266_RS09005
uniprot id: A0A448KE52
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

52774:EL266 RS12145
gene id: 52774:EL266_RS12145
uniprot id: A0A3S4SR53
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

52774:EL266 RS10755
gene id: 52774:EL266_RS10755
uniprot id: A0A448KF12
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

52774:EL266 RS12445
gene id: 52774:EL266_RS12445
uniprot id: A0A448KG03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

52774:EL266 RS02985
gene id: 52774:EL266_RS02985
uniprot id: A0A3S4WJ15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

52774:EL266 RS13845
gene id: 52774:EL266_RS13845
uniprot id: A0A448KA93
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

52774:EL266 RS12575
gene id: 52774:EL266_RS12575
uniprot id: A0A3S4SR86
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

52774:EL266 RS07350
gene id: 52774:EL266_RS07350
uniprot id: A0A3S4UNU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS04040
gene id: 52774:EL266_RS04040
uniprot id: A0A3S4U1J3
names: Similarity
messages: Belongs to the AAA ATPase family.

52774:EL266 RS07170
gene id: 52774:EL266_RS07170
uniprot id: A0A448KD03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS00735
gene id: 52774:EL266_RS00735
uniprot id: A0A448K9J5
names: Similarity
messages: Belongs to the GARS family.

52774:EL266 RS02735
gene id: 52774:EL266_RS02735
uniprot id: A0A448KAJ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

52774:EL266 RS05895
gene id: 52774:EL266_RS05895
uniprot id: A0A3S4UNC7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

52774:EL266 RS05090
gene id: 52774:EL266_RS05090
uniprot id: A0A3S4SET2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

52774:EL266 RS11440
gene id: 52774:EL266_RS11440
uniprot id: A0A448KFE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

52774:EL266 RS11450
gene id: 52774:EL266_RS11450
uniprot id: A0A448KFA6
names: Similarity
messages: Belongs to the P(II) protein family.

52774:EL266 RS02170
gene id: 52774:EL266_RS02170
uniprot id: A0A448KA74
names: Similarity
messages: Belongs to the thioredoxin family.

52774:EL266 RS10000
gene id: 52774:EL266_RS10000
uniprot id: A0A3S4SUG8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

52774:EL266 RS09960
gene id: 52774:EL266_RS09960
uniprot id: A0A3S5EMA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

52774:EL266 RS06480
gene id: 52774:EL266_RS06480
uniprot id: A0A448KCJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

52774:EL266 RS12160
gene id: 52774:EL266_RS12160
uniprot id: A0A3S4WII6
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

52774:EL266 RS09730
gene id: 52774:EL266_RS09730
uniprot id: A0A3S4SQE0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS11310
gene id: 52774:EL266_RS11310
uniprot id: A0A3S4WIA8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

52774:EL266 RS02860
gene id: 52774:EL266_RS02860
uniprot id: A0A448KAJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

52774:EL266 RS10980
gene id: 52774:EL266_RS10980
uniprot id: A0A448KF59
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

52774:EL266 RS06435
gene id: 52774:EL266_RS06435
uniprot id: A0A448KCM6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

52774:EL266 RS10280
gene id: 52774:EL266_RS10280
uniprot id: A0A3S4SUK4
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

52774:EL266 RS08705
gene id: 52774:EL266_RS08705
uniprot id: A0A3S4TD28
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

52774:EL266 RS10630
gene id: 52774:EL266_RS10630
uniprot id: A0A3S4SQM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

52774:EL266 RS00200
gene id: 52774:EL266_RS00200
uniprot id: A0A3S4TAM6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

52774:EL266 RS01900
gene id: 52774:EL266_RS01900
uniprot id: A0A3S4WIP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS07435
gene id: 52774:EL266_RS07435
uniprot id: A0A448KD48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

52774:EL266 RS02125
gene id: 52774:EL266_RS02125
uniprot id: A0A3S4WFI7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

52774:EL266 RS09490
gene id: 52774:EL266_RS09490
uniprot id: A0A448KE93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

52774:EL266 RS03885
gene id: 52774:EL266_RS03885
uniprot id: A0A3S4UMR7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

52774:EL266 RS08390
gene id: 52774:EL266_RS08390
uniprot id: A0A3S4U2Q5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

52774:EL266 RS09770
gene id: 52774:EL266_RS09770
uniprot id: A0A448KEI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

52774:EL266 RS07185
gene id: 52774:EL266_RS07185
uniprot id: A0A3S4SPJ6
names: Similarity
messages: Belongs to the DapA family.

52774:EL266 RS04330
gene id: 52774:EL266_RS04330
uniprot id: A0A448KBF6
names: Similarity
messages: Belongs to the universal stress protein A family.

52774:EL266 RS04230
gene id: 52774:EL266_RS04230
uniprot id: A0A3S4SNM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

52774:EL266 RS07095
gene id: 52774:EL266_RS07095
uniprot id: A0A448KD18
names: Similarity
messages: Belongs to the FPG family.

52774:EL266 RS11345
gene id: 52774:EL266_RS11345
uniprot id: A0A448KF98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

52774:EL266 RS00585
gene id: 52774:EL266_RS00585
uniprot id: A0A448K967
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

52774:EL266 RS08455
gene id: 52774:EL266_RS08455
uniprot id: A0A3S4SU20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

52774:EL266 RS11215
gene id: 52774:EL266_RS11215
uniprot id: A0A3S4WI94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS05485
gene id: 52774:EL266_RS05485
uniprot id: A0A3S4WGM4
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

52774:EL266 RS13270
gene id: 52774:EL266_RS13270
uniprot id: A0A448KGA4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

52774:EL266 RS12785
gene id: 52774:EL266_RS12785
uniprot id: A0A3S4WM07
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

52774:EL266 RS02650
gene id: 52774:EL266_RS02650
uniprot id: A0A3S4U155
names: Similarity
messages: Belongs to the thioredoxin family.

52774:EL266 RS06360
gene id: 52774:EL266_RS06360
uniprot id: A0A3S4STF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

52774:EL266 RS06110
gene id: 52774:EL266_RS06110
uniprot id: A0A3S4WGU5
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS06740
gene id: 52774:EL266_RS06740
uniprot id: A0A3S4UNN6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

52774:EL266 RS05785
gene id: 52774:EL266_RS05785
uniprot id: A0A448KC69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

52774:EL266 RS01030
gene id: 52774:EL266_RS01030
uniprot id: A0A3S4WIG2
names: Subcellular Location Annotation
messages: Cytoplasm

52774:EL266 RS06015
gene id: 52774:EL266_RS06015
uniprot id: A0A3S4U228
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS00530
gene id: 52774:EL266_RS00530
uniprot id: A0A448K9F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS05465
gene id: 52774:EL266_RS05465
uniprot id: A0A3S4WJS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

52774:EL266 RS05170
gene id: 52774:EL266_RS05170
uniprot id: A0A3S4U1V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

52774:EL266 RS09585
gene id: 52774:EL266_RS09585
uniprot id: A0A448KEC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

52774:EL266 RS06715
gene id: 52774:EL266_RS06715
uniprot id: A0A3S4WH13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

52774:EL266 RS10645
gene id: 52774:EL266_RS10645
uniprot id: A0A3S4WI37
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

52774:EL266 RS11235
gene id: 52774:EL266_RS11235
uniprot id: A0A448KFB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

52774:EL266 RS10890
gene id: 52774:EL266_RS10890
uniprot id: A0A448KEZ3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

52774:EL266 RS01830
gene id: 52774:EL266_RS01830
uniprot id: A0A3S4SN09
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

52774:EL266 RS00220
gene id: 52774:EL266_RS00220
uniprot id: A0A3S4SMI7
names: Similarity
messages: Belongs to the ribulokinase family.

52774:EL266 RS11040
gene id: 52774:EL266_RS11040
uniprot id: A0A448KF37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

52774:EL266 RS00110
gene id: 52774:EL266_RS00110
uniprot id: A0A448K976
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

52774:EL266 RS09640
gene id: 52774:EL266_RS09640
uniprot id: A0A448KEC9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

52774:EL266 RS07330
gene id: 52774:EL266_RS07330
uniprot id: A0A448KD21
names: Cofactor
messages: Binds 1 zinc ion per subunit.

52774:EL266 RS09540
gene id: 52774:EL266_RS09540
uniprot id: A0A448KEA5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

52774:EL266 RS08195
gene id: 52774:EL266_RS08195
uniprot id: A0A448KDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS08325
gene id: 52774:EL266_RS08325
uniprot id: A0A448KDL0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

52774:EL266 RS04645
gene id: 52774:EL266_RS04645
uniprot id: A0A448KBL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

52774:EL266 RS08745
gene id: 52774:EL266_RS08745
uniprot id: A0A3S4SQ10
names: Similarity
messages: Belongs to the AAA ATPase family.

52774:EL266 RS02275
gene id: 52774:EL266_RS02275
uniprot id: A0A3S4TB56
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS01485
gene id: 52774:EL266_RS01485
uniprot id: A0A448K9V5
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS10770
gene id: 52774:EL266_RS10770
uniprot id: A0A3S4UPU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

52774:EL266 RS10465
gene id: 52774:EL266_RS10465
uniprot id: A0A448KEW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS04360
gene id: 52774:EL266_RS04360
uniprot id: A0A448KBG4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

52774:EL266 RS01375
gene id: 52774:EL266_RS01375
uniprot id: A0A3S4WIJ4
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS03190
gene id: 52774:EL266_RS03190
uniprot id: A0A3S4UMI6
names: Subcellular Location Annotation
messages: Cell membrane

52774:EL266 RS11105
gene id: 52774:EL266_RS11105
uniprot id: A0A448KF52
names: Similarity
messages: Belongs to the ribF family.

52774:EL266 RS01720
gene id: 52774:EL266_RS01720
uniprot id: A0A448K9Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

52774:EL266 RS06600
gene id: 52774:EL266_RS06600
uniprot id: A0A448KCP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

52774:EL266 RS04300
gene id: 52774:EL266_RS04300
uniprot id: A0A448KBF1
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

52774:EL266 RS12025
gene id: 52774:EL266_RS12025
uniprot id: A0A448KFR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS07005
gene id: 52774:EL266_RS07005
uniprot id: A0A3S4UNR7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

52774:EL266 RS11270
gene id: 52774:EL266_RS11270
uniprot id: A0A3S4WLK9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS00095
gene id: 52774:EL266_RS00095
uniprot id: A0A3S4ULK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS12045
gene id: 52774:EL266_RS12045
uniprot id: A0A448KFM3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

52774:EL266 RS04440
gene id: 52774:EL266_RS04440
uniprot id: A0A448KBF5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

52774:EL266 RS06825
gene id: 52774:EL266_RS06825
uniprot id: A0A448KCS4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

52774:EL266 RS02875
gene id: 52774:EL266_RS02875
uniprot id: A0A3S4SSG8
names: Similarity
messages: Belongs to the UPF0045 family.

52774:EL266 RS02905
gene id: 52774:EL266_RS02905
uniprot id: A0A448KAL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

52774:EL266 RS02515
gene id: 52774:EL266_RS02515
uniprot id: A0A3S4SN63
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS05100
gene id: 52774:EL266_RS05100
uniprot id: A0A3S4TBZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

52774:EL266 RS05145
gene id: 52774:EL266_RS05145
uniprot id: A0A448KBU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

52774:EL266 RS01025
gene id: 52774:EL266_RS01025
uniprot id: A0A448K9N9
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS03620
gene id: 52774:EL266_RS03620
uniprot id: A0A448KB01
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS08840
gene id: 52774:EL266_RS08840
uniprot id: A0A3S4SQ17
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

52774:EL266 RS07355
gene id: 52774:EL266_RS07355
uniprot id: A0A448KD29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS09470
gene id: 52774:EL266_RS09470
uniprot id: A0A3S4WL33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

52774:EL266 RS05885
gene id: 52774:EL266_RS05885
uniprot id: A0A3S4ST95
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

52774:EL266 RS04115
gene id: 52774:EL266_RS04115
uniprot id: A0A448KBA5
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS00775
gene id: 52774:EL266_RS00775
uniprot id: A0A3S4SRU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

52774:EL266 RS10365
gene id: 52774:EL266_RS10365
uniprot id: A0A3S4SLC1
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

52774:EL266 RS10415
gene id: 52774:EL266_RS10415
uniprot id: A0A448KEV4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

52774:EL266 RS07090
gene id: 52774:EL266_RS07090
uniprot id: A0A448KCZ5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

52774:EL266 RS07720
gene id: 52774:EL266_RS07720
uniprot id: A0A448KDF1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

52774:EL266 RS03865
gene id: 52774:EL266_RS03865
uniprot id: A0A3S4WG19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

52774:EL266 RS05345
gene id: 52774:EL266_RS05345
uniprot id: A0A3S4SEV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

52774:EL266 RS11140
gene id: 52774:EL266_RS11140
uniprot id: A0A448KF61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

52774:EL266 RS07465
gene id: 52774:EL266_RS07465
uniprot id: A0A3S4STR8
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

52774:EL266 RS04880
gene id: 52774:EL266_RS04880
uniprot id: A0A448KBR0
names: Similarity
messages: Belongs to the peptidase S13 family.

52774:EL266 RS12980
gene id: 52774:EL266_RS12980
uniprot id: A0A448KGA6
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

52774:EL266 RS07270
gene id: 52774:EL266_RS07270
uniprot id: A0A3S4WKE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

52774:EL266 RS11525
gene id: 52774:EL266_RS11525
uniprot id: A0A448KFG2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

52774:EL266 RS11305
gene id: 52774:EL266_RS11305
uniprot id: A0A3S4SLK2
names: Similarity
messages: Belongs to the DprA/Smf family.

52774:EL266 RS09740
gene id: 52774:EL266_RS09740
uniprot id: A0A3S4SL63
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

52774:EL266 RS05105
gene id: 52774:EL266_RS05105
uniprot id: A0A448KBX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

52774:EL266 RS08175
gene id: 52774:EL266_RS08175
uniprot id: A0A448KDK1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

52774:EL266 RS11725
gene id: 52774:EL266_RS11725
uniprot id: A0A448KFI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

52774:EL266 RS00215
gene id: 52774:EL266_RS00215
uniprot id: A0A448K8Y8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

52774:EL266 RS00395
gene id: 52774:EL266_RS00395
uniprot id: A0A3S4SIM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

52774:EL266 RS05245
gene id: 52774:EL266_RS05245
uniprot id: A0A448KBW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

52774:EL266 RS01445
gene id: 52774:EL266_RS01445
uniprot id: A0A3S4U0T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

52774:EL266 RS01790
gene id: 52774:EL266_RS01790
uniprot id: A0A3S4UM37
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS11290
gene id: 52774:EL266_RS11290
uniprot id: A0A3S5EMC1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

52774:EL266 RS10930
gene id: 52774:EL266_RS10930
uniprot id: A0A448KF48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

52774:EL266 RS04590
gene id: 52774:EL266_RS04590
uniprot id: A0A448KBK6
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

52774:EL266 RS07920
gene id: 52774:EL266_RS07920
uniprot id: A0A3S4U2L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

52774:EL266 RS06970
gene id: 52774:EL266_RS06970
uniprot id: A0A448KCU1
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS06430
gene id: 52774:EL266_RS06430
uniprot id: A0A3S4U267
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

52774:EL266 RS00870
gene id: 52774:EL266_RS00870
uniprot id: A0A3S4U0M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

52774:EL266 RS11580
gene id: 52774:EL266_RS11580
uniprot id: A0A3S4WLN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS04235
gene id: 52774:EL266_RS04235
uniprot id: A0A448KBD3
names: Similarity
messages: Belongs to the WXG100 family.

52774:EL266 RS03520
gene id: 52774:EL266_RS03520
uniprot id: A0A3S4SEB7
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

52774:EL266 RS07740
gene id: 52774:EL266_RS07740
uniprot id: A0A448KDA6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

52774:EL266 RS11985
gene id: 52774:EL266_RS11985
uniprot id: A0A448KFL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS11280
gene id: 52774:EL266_RS11280
uniprot id: A0A448KFC9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

52774:EL266 RS10295
gene id: 52774:EL266_RS10295
uniprot id: A0A3S4UPQ1
names: Similarity
messages: Belongs to the CdaR family.

52774:EL266 RS01035
gene id: 52774:EL266_RS01035
uniprot id: A0A3S5EM16
names: Subcellular Location Annotation
messages: Cytoplasm

52774:EL266 RS11365
gene id: 52774:EL266_RS11365
uniprot id: A0A3S4WLM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

52774:EL266 RS03225
gene id: 52774:EL266_RS03225
uniprot id: A0A3S4WJ37
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

52774:EL266 RS02350
gene id: 52774:EL266_RS02350
uniprot id: A0A448KAA5
names: Similarity
messages: Belongs to the peptidase S8 family.

52774:EL266 RS10665
gene id: 52774:EL266_RS10665
uniprot id: A0A3S4U3B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS00615
gene id: 52774:EL266_RS00615
uniprot id: A0A3S4WIC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

52774:EL266 RS05795
gene id: 52774:EL266_RS05795
uniprot id: A0A448KC84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

52774:EL266 RS06720
gene id: 52774:EL266_RS06720
uniprot id: A0A3S4U298
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

52774:EL266 RS11625
gene id: 52774:EL266_RS11625
uniprot id: A0A3S4SUW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

52774:EL266 RS09795
gene id: 52774:EL266_RS09795
uniprot id: A0A3S4UPJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

52774:EL266 RS03860
gene id: 52774:EL266_RS03860
uniprot id: A0A3S4SJI6
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

52774:EL266 RS08990
gene id: 52774:EL266_RS08990
uniprot id: A0A3S4TD64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

52774:EL266 RS08735
gene id: 52774:EL266_RS08735
uniprot id: A0A448KDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

52774:EL266 RS08865
gene id: 52774:EL266_RS08865
uniprot id: A0A3S4UP94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

52774:EL266 RS08755
gene id: 52774:EL266_RS08755
uniprot id: A0A3S4SKW9
names: Similarity
messages: Belongs to the prokaryotic ubiquitin-like protein family.

52774:EL266 RS05060
gene id: 52774:EL266_RS05060
uniprot id: A0A448KBV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

52774:EL266 RS07795
gene id: 52774:EL266_RS07795
uniprot id: A0A448KDB9
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS11350
gene id: 52774:EL266_RS11350
uniprot id: A0A3S4SGP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

52774:EL266 RS07990
gene id: 52774:EL266_RS07990
uniprot id: A0A448KDG3
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS10120
gene id: 52774:EL266_RS10120
uniprot id: A0A3S4SUH7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

52774:EL266 RS03565
gene id: 52774:EL266_RS03565
uniprot id: A0A448KB03
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

52774:EL266 RS11775
gene id: 52774:EL266_RS11775
uniprot id: A0A3S4SLQ2
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS00975
gene id: 52774:EL266_RS00975
uniprot id: A0A3S4U0N4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

52774:EL266 RS07175
gene id: 52774:EL266_RS07175
uniprot id: A0A3S5EM80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS05260
gene id: 52774:EL266_RS05260
uniprot id: A0A448KBZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

52774:EL266 RS06660
gene id: 52774:EL266_RS06660
uniprot id: A0A3S4STI2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

52774:EL266 RS00390
gene id: 52774:EL266_RS00390
uniprot id: A0A3S4SMK2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

52774:EL266 RS06310
gene id: 52774:EL266_RS06310
uniprot id: A0A448KCJ4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

52774:EL266 RS07585
gene id: 52774:EL266_RS07585
uniprot id: A0A3S5EM84
names: Similarity
messages: Belongs to the diaminopimelate epimerase family.

52774:EL266 RS12440
gene id: 52774:EL266_RS12440
uniprot id: A0A3S4SH09
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

52774:EL266 RS08165
gene id: 52774:EL266_RS08165
uniprot id: A0A448KDH9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

52774:EL266 RS07035
gene id: 52774:EL266_RS07035
uniprot id: A0A448KD23
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

52774:EL266 RS10445
gene id: 52774:EL266_RS10445
uniprot id: A0A448KEV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS10490
gene id: 52774:EL266_RS10490
uniprot id: A0A448KEQ7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS10710
gene id: 52774:EL266_RS10710
uniprot id: A0A3S4WLF9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

52774:EL266 RS02110
gene id: 52774:EL266_RS02110
uniprot id: A0A3S4SN42
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

52774:EL266 RS02085
gene id: 52774:EL266_RS02085
uniprot id: A0A3S4WIR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

52774:EL266 RS00810
gene id: 52774:EL266_RS00810
uniprot id: A0A3S4SDH6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS09975
gene id: 52774:EL266_RS09975
uniprot id: A0A3S4SL89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

52774:EL266 RS10035
gene id: 52774:EL266_RS10035
uniprot id: A0A448KEL5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

52774:EL266 RS07550
gene id: 52774:EL266_RS07550
uniprot id: A0A3S4SFK8
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS09920
gene id: 52774:EL266_RS09920
uniprot id: A0A3S4SUF8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

52774:EL266 RS00290
gene id: 52774:EL266_RS00290
uniprot id: A0A3S4SMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

52774:EL266 RS01835
gene id: 52774:EL266_RS01835
uniprot id: A0A3S4SIZ6
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

52774:EL266 RS00150
gene id: 52774:EL266_RS00150
uniprot id: A0A448K992
names: Similarity
messages: Belongs to the UPF0225 family.

52774:EL266 RS11265
gene id: 52774:EL266_RS11265
uniprot id: A0A3S4TDR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

52774:EL266 RS05870
gene id: 52774:EL266_RS05870
uniprot id: A0A3S4WGR5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

52774:EL266 RS04460
gene id: 52774:EL266_RS04460
uniprot id: A0A3S4WGB7
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

52774:EL266 RS00015
gene id: 52774:EL266_RS00015
uniprot id: A0A3S4ULJ0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

52774:EL266 RS08435
gene id: 52774:EL266_RS08435
uniprot id: A0A448KDT7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

52774:EL266 RS00880
gene id: 52774:EL266_RS00880
uniprot id: A0A3S4ULU3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS03560
gene id: 52774:EL266_RS03560
uniprot id: A0A3S5EM42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

52774:EL266 RS03215
gene id: 52774:EL266_RS03215
uniprot id: A0A448KAS9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS02355
gene id: 52774:EL266_RS02355
uniprot id: A0A448KAA2
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

52774:EL266 RS04205
gene id: 52774:EL266_RS04205
uniprot id: A0A3S4SEI8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS06475
gene id: 52774:EL266_RS06475
uniprot id: A0A3S4SF91
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

52774:EL266 RS02435
gene id: 52774:EL266_RS02435
uniprot id: A0A3S4SJ45
names: Similarity
messages: Belongs to the CsoR family.

52774:EL266 RS13310
gene id: 52774:EL266_RS13310
uniprot id: A0A448KGG1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

52774:EL266 RS10605
gene id: 52774:EL266_RS10605
uniprot id: A0A448KEY0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS08860
gene id: 52774:EL266_RS08860
uniprot id: A0A3S4U2V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

52774:EL266 RS05130
gene id: 52774:EL266_RS05130
uniprot id: A0A3S5EM58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

52774:EL266 RS00070
gene id: 52774:EL266_RS00070
uniprot id: A0A3S4U0D4
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

52774:EL266 RS04520
gene id: 52774:EL266_RS04520
uniprot id: A0A3S5EM52
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS10945
gene id: 52774:EL266_RS10945
uniprot id: A0A3S4WI66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

52774:EL266 RS01080
gene id: 52774:EL266_RS01080
uniprot id: A0A3S4U0P5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

52774:EL266 RS03100
gene id: 52774:EL266_RS03100
uniprot id: A0A3S4WJ24
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

52774:EL266 RS02580
gene id: 52774:EL266_RS02580
uniprot id: A0A3S4UMB8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

52774:EL266 RS02915
gene id: 52774:EL266_RS02915
uniprot id: A0A3S5EM35
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS05900
gene id: 52774:EL266_RS05900
uniprot id: A0A448KCB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

52774:EL266 RS13210
gene id: 52774:EL266_RS13210
uniprot id: A0A448KGA0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

52774:EL266 RS06380
gene id: 52774:EL266_RS06380
uniprot id: A0A3S4TCE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS08180
gene id: 52774:EL266_RS08180
uniprot id: A0A3S4STZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

52774:EL266 RS05635
gene id: 52774:EL266_RS05635
uniprot id: A0A3S4SK08
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS13150
gene id: 52774:EL266_RS13150
uniprot id: A0A3S4TEA2
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS09025
gene id: 52774:EL266_RS09025
uniprot id: A0A3S5EM98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

52774:EL266 RS00860
gene id: 52774:EL266_RS00860
uniprot id: A0A448K9H2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

52774:EL266 RS04865
gene id: 52774:EL266_RS04865
uniprot id: A0A448KBM8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

52774:EL266 RS01405
gene id: 52774:EL266_RS01405
uniprot id: A0A448K9S9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

52774:EL266 RS07200
gene id: 52774:EL266_RS07200
uniprot id: A0A3S4WH63
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

52774:EL266 RS09035
gene id: 52774:EL266_RS09035
uniprot id: A0A448KE07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

52774:EL266 RS11590
gene id: 52774:EL266_RS11590
uniprot id: A0A3S4SQZ9
names: Similarity
messages: Belongs to the prokaryotic ubiquitin-like protein family.

52774:EL266 RS03250
gene id: 52774:EL266_RS03250
uniprot id: A0A3S4SJB8
names: Similarity
messages: Belongs to the DDAH family.

52774:EL266 RS05745
gene id: 52774:EL266_RS05745
uniprot id: A0A3S4SK18
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS07750
gene id: 52774:EL266_RS07750
uniprot id: A0A3S4TCT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

52774:EL266 RS07700
gene id: 52774:EL266_RS07700
uniprot id: A0A3S4STU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS12730
gene id: 52774:EL266_RS12730
uniprot id: A0A3S4U3W6
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS06830
gene id: 52774:EL266_RS06830
uniprot id: A0A448KCS5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

52774:EL266 RS11090
gene id: 52774:EL266_RS11090
uniprot id: A0A448KF47
names: Similarity
messages: Belongs to the catalase family.

52774:EL266 RS05175
gene id: 52774:EL266_RS05175
uniprot id: A0A3S4ST22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

52774:EL266 RS11735
gene id: 52774:EL266_RS11735
uniprot id: A0A3S4SGT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

52774:EL266 RS01000
gene id: 52774:EL266_RS01000
uniprot id: A0A448K9J8
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

52774:EL266 RS07770
gene id: 52774:EL266_RS07770
uniprot id: A0A3S4SPR0
names: Similarity
messages: Belongs to the FPG family.

52774:EL266 RS06405
gene id: 52774:EL266_RS06405
uniprot id: A0A448KCJ6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

52774:EL266 RS09665
gene id: 52774:EL266_RS09665
uniprot id: A0A3S4SL57
names: Similarity
messages: Belongs to the amidinotransferase family.

52774:EL266 RS07540
gene id: 52774:EL266_RS07540
uniprot id: A0A448KDA4
names: Similarity
messages: Belongs to the UPF0423 family.

52774:EL266 RS07590
gene id: 52774:EL266_RS07590
uniprot id: A0A448KDB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

52774:EL266 RS09780
gene id: 52774:EL266_RS09780
uniprot id: A0A448KED5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

52774:EL266 RS00040
gene id: 52774:EL266_RS00040
uniprot id: A0A3S4WI59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

52774:EL266 RS00555
gene id: 52774:EL266_RS00555
uniprot id: A0A448K9G6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS08250
gene id: 52774:EL266_RS08250
uniprot id: A0A3S4SKS6
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS13000
gene id: 52774:EL266_RS13000
uniprot id: A0A448KGA7
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS12585
gene id: 52774:EL266_RS12585
uniprot id: A0A448KG28
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

52774:EL266 RS05810
gene id: 52774:EL266_RS05810
uniprot id: A0A448KC68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

52774:EL266 RS07055
gene id: 52774:EL266_RS07055
uniprot id: A0A448KCW5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

52774:EL266 RS03730
gene id: 52774:EL266_RS03730
uniprot id: A0A448KB50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

52774:EL266 RS07470
gene id: 52774:EL266_RS07470
uniprot id: A0A3S4UNV6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

52774:EL266 RS05295
gene id: 52774:EL266_RS05295
uniprot id: A0A448KBX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

52774:EL266 RS07835
gene id: 52774:EL266_RS07835
uniprot id: A0A448KDF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

52774:EL266 RS09710
gene id: 52774:EL266_RS09710
uniprot id: A0A3S4TDC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

52774:EL266 RS11095
gene id: 52774:EL266_RS11095
uniprot id: A0A3S4SGL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

52774:EL266 RS05195
gene id: 52774:EL266_RS05195
uniprot id: A0A448KBV0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

52774:EL266 RS05210
gene id: 52774:EL266_RS05210
uniprot id: A0A448KBY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

52774:EL266 RS02485
gene id: 52774:EL266_RS02485
uniprot id: A0A3S4TB74
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

52774:EL266 RS11455
gene id: 52774:EL266_RS11455
uniprot id: A0A3S4TDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS05520
gene id: 52774:EL266_RS05520
uniprot id: A0A3S4UN82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

52774:EL266 RS12135
gene id: 52774:EL266_RS12135
uniprot id: A0A448KFP1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

52774:EL266 RS09735
gene id: 52774:EL266_RS09735
uniprot id: A0A448KEE9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

52774:EL266 RS05700
gene id: 52774:EL266_RS05700
uniprot id: A0A3S4UNA4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

52774:EL266 RS08260
gene id: 52774:EL266_RS08260
uniprot id: A0A448KDJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

52774:EL266 RS10615
gene id: 52774:EL266_RS10615
uniprot id: A0A3S5EMB4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

52774:EL266 RS12590
gene id: 52774:EL266_RS12590
uniprot id: A0A3S4WIN4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

52774:EL266 RS03505
gene id: 52774:EL266_RS03505
uniprot id: A0A3S4SSN0
names: Similarity
messages: Belongs to the Dps family.

52774:EL266 RS05890
gene id: 52774:EL266_RS05890
uniprot id: A0A448KCE1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

52774:EL266 RS09405
gene id: 52774:EL266_RS09405
uniprot id: A0A3S4U2Z8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

52774:EL266 RS08105
gene id: 52774:EL266_RS08105
uniprot id: A0A3S4TCX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Belongs to the TrpC family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

52774:EL266 RS09650
gene id: 52774:EL266_RS09650
uniprot id: A0A3S5EMA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

52774:EL266 RS07985
gene id: 52774:EL266_RS07985
uniprot id: A0A3S4TCV9
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

52774:EL266 RS12220
gene id: 52774:EL266_RS12220
uniprot id: A0A448KFT0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

52774:EL266 RS12825
gene id: 52774:EL266_RS12825
uniprot id: A0A448KG74
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

52774:EL266 RS09370
gene id: 52774:EL266_RS09370
uniprot id: A0A3S5EMA1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS08900
gene id: 52774:EL266_RS08900
uniprot id: A0A3S5EM97
names: Similarity
messages: Belongs to the YciI family.

52774:EL266 RS04015
gene id: 52774:EL266_RS04015
uniprot id: A0A3S4WJC6
names: Similarity
messages: Belongs to the heat shock protein 90 family.

52774:EL266 RS02945
gene id: 52774:EL266_RS02945
uniprot id: A0A3S4U185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

52774:EL266 RS12070
gene id: 52774:EL266_RS12070
uniprot id: A0A3S4UQ78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

52774:EL266 RS11205
gene id: 52774:EL266_RS11205
uniprot id: A0A3S4SLI9
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

52774:EL266 RS06770
gene id: 52774:EL266_RS06770
uniprot id: A0A3S5EM76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS10140
gene id: 52774:EL266_RS10140
uniprot id: A0A3S4TDG7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

52774:EL266 RS10660
gene id: 52774:EL266_RS10660
uniprot id: A0A448KEY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS13320
gene id: 52774:EL266_RS13320
uniprot id: A0A3S4UQK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

52774:EL266 RS07605
gene id: 52774:EL266_RS07605
uniprot id: A0A3S4WHA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

52774:EL266 RS07105
gene id: 52774:EL266_RS07105
uniprot id: A0A3S4U2D5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

52774:EL266 RS00620
gene id: 52774:EL266_RS00620
uniprot id: A0A3S5EM12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

52774:EL266 RS06185
gene id: 52774:EL266_RS06185
uniprot id: A0A3S4U241
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

52774:EL266 RS07710
gene id: 52774:EL266_RS07710
uniprot id: A0A448KDA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

52774:EL266 RS01745
gene id: 52774:EL266_RS01745
uniprot id: A0A448K9Z8
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS07635
gene id: 52774:EL266_RS07635
uniprot id: A0A3S4SFM0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS11025
gene id: 52774:EL266_RS11025
uniprot id: A0A3S4SQR4
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

52774:EL266 RS07195
gene id: 52774:EL266_RS07195
uniprot id: A0A448KD46
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

52774:EL266 RS05000
gene id: 52774:EL266_RS05000
uniprot id: A0A3S4SER7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52774:EL266 RS10350
gene id: 52774:EL266_RS10350
uniprot id: A0A3S5EMB2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

52774:EL266 RS05445
gene id: 52774:EL266_RS05445
uniprot id: A0A448KC00
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

52774:EL266 RS12915
gene id: 52774:EL266_RS12915
uniprot id: A0A448KG96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

52774:EL266 RS09330
gene id: 52774:EL266_RS09330
uniprot id: A0A3S4SU98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

52774:EL266 RS00010
gene id: 52774:EL266_RS00010
uniprot id: A0A3S4SRN2
names: Similarity
messages: Belongs to the CsoR family.

52774:EL266 RS07265
gene id: 52774:EL266_RS07265
uniprot id: A0A448KD09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

52774:EL266 RS02680
gene id: 52774:EL266_RS02680
uniprot id: A0A3S4TB92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.

52774:EL266 RS11945
gene id: 52774:EL266_RS11945
uniprot id: A0A3S4WIG7
names: Similarity
messages: Belongs to the HepT RNase toxin family.

52774:EL266 RS00930
gene id: 52774:EL266_RS00930
uniprot id: A0A3S4WIF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52774:EL266 RS07870
gene id: 52774:EL266_RS07870
uniprot id: A0A448KDD5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

52774:EL266 RS10960
gene id: 52774:EL266_RS10960
uniprot id: A0A448KF62
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS11245
gene id: 52774:EL266_RS11245
uniprot id: A0A3S4SUT0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52774:EL266 RS03640
gene id: 52774:EL266_RS03640
uniprot id: A0A3S4UMN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

52774:EL266 RS06855
gene id: 52774:EL266_RS06855
uniprot id: A0A448KCS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

52774:EL266 RS06270
gene id: 52774:EL266_RS06270
uniprot id: A0A3S4STD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

52774:EL266 RS10455
gene id: 52774:EL266_RS10455
uniprot id: A0A3S4SLD1
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

52774:EL266 RS00475
gene id: 52774:EL266_RS00475
uniprot id: A0A3S4U0I0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

52774:EL266 RS06230
gene id: 52774:EL266_RS06230
uniprot id: A0A3S5EM70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS08905
gene id: 52774:EL266_RS08905
uniprot id: A0A3S4SQ59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

52774:EL266 RS07765
gene id: 52774:EL266_RS07765
uniprot id: A0A3S5EM86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

52774:EL266 RS11545
gene id: 52774:EL266_RS11545
uniprot id: A0A448KFG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

52774:EL266 RS10590
gene id: 52774:EL266_RS10590
uniprot id: A0A448KEW8
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

52774:EL266 RS05065
gene id: 52774:EL266_RS05065
uniprot id: A0A3S4WGI2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

52774:EL266 RS03220
gene id: 52774:EL266_RS03220
uniprot id: A0A3S4TBD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

52774:EL266 RS06415
gene id: 52774:EL266_RS06415
uniprot id: A0A448KCI8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

52774:EL266 RS08280
gene id: 52774:EL266_RS08280
uniprot id: A0A448KDM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS12890
gene id: 52774:EL266_RS12890
uniprot id: A0A448KG36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

52774:EL266 RS05280
gene id: 52774:EL266_RS05280
uniprot id: A0A448KBW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

52774:EL266 RS03065
gene id: 52774:EL266_RS03065
uniprot id: A0A448KAR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

52774:EL266 RS12335
gene id: 52774:EL266_RS12335
uniprot id: A0A3S4SGZ9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

52774:EL266 RS05125
gene id: 52774:EL266_RS05125
uniprot id: A0A448KBT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

52774:EL266 RS08915
gene id: 52774:EL266_RS08915
uniprot id: A0A448KDX7
names: Similarity
messages: Belongs to the UDPGP type 1 family.

52774:EL266 RS08170
gene id: 52774:EL266_RS08170
uniprot id: A0A3S4U2N6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

52774:EL266 RS08955
gene id: 52774:EL266_RS08955
uniprot id: A0A3S4SG15
names: Subcellular Location Annotation
messages: Membrane

52774:EL266 RS05155
gene id: 52774:EL266_RS05155
uniprot id: A0A3S4SNU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

52774:EL266 RS07820
gene id: 52774:EL266_RS07820
uniprot id: A0A3S4U2K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

52774:EL266 RS01240
gene id: 52774:EL266_RS01240
uniprot id: A0A3S4SIV0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

52774:EL266 RS07100
gene id: 52774:EL266_RS07100
uniprot id: A0A3S4WH51
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

52774:EL266 RS13285
gene id: 52774:EL266_RS13285
uniprot id: A0A448KGF9
names: Similarity
messages: Belongs to the peptidase A24 family.

52774:EL266 RS10500
gene id: 52774:EL266_RS10500
uniprot id: A0A448KEW0
names: Subcellular Location Annotation
messages: Membrane