52773:I6H42 RS05280
gene id: 52773:I6H42_RS05280
uniprot id: A0A1H1P0K6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

52773:I6H42 RS07855
gene id: 52773:I6H42_RS07855
uniprot id: A0A1H1Q276
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

52773:I6H42 RS05005
gene id: 52773:I6H42_RS05005
uniprot id: A0A1H1P7Q0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

52773:I6H42 RS03985
gene id: 52773:I6H42_RS03985
uniprot id: A0A1H1KQQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

52773:I6H42 RS06015
gene id: 52773:I6H42_RS06015
uniprot id: A0A1H1MNP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

52773:I6H42 RS02810
gene id: 52773:I6H42_RS02810
uniprot id: A0A1H1KRN4
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

52773:I6H42 RS00840
gene id: 52773:I6H42_RS00840
uniprot id: A0A1H1KW68
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

52773:I6H42 RS01190
gene id: 52773:I6H42_RS01190
uniprot id: A0A1H1L645
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

52773:I6H42 RS08600
gene id: 52773:I6H42_RS08600
uniprot id: A0A1H1LGP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

52773:I6H42 RS05295
gene id: 52773:I6H42_RS05295
uniprot id: A0A1H1P0S8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

52773:I6H42 RS02535
gene id: 52773:I6H42_RS02535
uniprot id: A0A1H1KTJ8
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

52773:I6H42 RS04600
gene id: 52773:I6H42_RS04600
uniprot id: A0A1H1KQ62
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS07850
gene id: 52773:I6H42_RS07850
uniprot id: A0A1H1Q1B4
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

52773:I6H42 RS02430
gene id: 52773:I6H42_RS02430
uniprot id: A0A1H1KS61
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

52773:I6H42 RS03545
gene id: 52773:I6H42_RS03545
uniprot id: A0A1H1KQX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

52773:I6H42 RS04700
gene id: 52773:I6H42_RS04700
uniprot id: A0A1H1PE61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

52773:I6H42 RS03660
gene id: 52773:I6H42_RS03660
uniprot id: A0A1H1KQS2
names: Similarity
messages: Belongs to the DEAD box helicase family.

52773:I6H42 RS07790
gene id: 52773:I6H42_RS07790
uniprot id: A0A1H1Q3S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

52773:I6H42 RS02905
gene id: 52773:I6H42_RS02905
uniprot id: A0A1H1KS59
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS06115
gene id: 52773:I6H42_RS06115
uniprot id: A0A1H1MQH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

52773:I6H42 RS06970
gene id: 52773:I6H42_RS06970
uniprot id: A0A1H1NAL4
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS01625
gene id: 52773:I6H42_RS01625
uniprot id: A0A1H1L141
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

52773:I6H42 RS03890
gene id: 52773:I6H42_RS03890
uniprot id: A0A1H1KQN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

52773:I6H42 RS01205
gene id: 52773:I6H42_RS01205
uniprot id: A0A1H1L629
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

52773:I6H42 RS05170
gene id: 52773:I6H42_RS05170
uniprot id: A0A1H1P374
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

52773:I6H42 RS00730
gene id: 52773:I6H42_RS00730
uniprot id: A0A1H1KVZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS04140
gene id: 52773:I6H42_RS04140
uniprot id: A0A1H1KQN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

52773:I6H42 RS04585
gene id: 52773:I6H42_RS04585
uniprot id: A0A1H1KQ73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

52773:I6H42 RS02260
gene id: 52773:I6H42_RS02260
uniprot id: A0A1H1M1G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

52773:I6H42 RS03170
gene id: 52773:I6H42_RS03170
uniprot id: A0A1H1KQW5
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

52773:I6H42 RS02985
gene id: 52773:I6H42_RS02985
uniprot id: A0A1H1KRF4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

52773:I6H42 RS05600
gene id: 52773:I6H42_RS05600
uniprot id: A0A1H1MCW2
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS00465
gene id: 52773:I6H42_RS00465
uniprot id: A0A1H1LXW8
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS06320
gene id: 52773:I6H42_RS06320
uniprot id: A0A1H1MVU7
names: Similarity
messages: Belongs to the WXG100 family.

52773:I6H42 RS08400
gene id: 52773:I6H42_RS08400
uniprot id: A0A1H1LCT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52773:I6H42 RS00310
gene id: 52773:I6H42_RS00310
uniprot id: A0A1H1LUL1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

52773:I6H42 RS04875
gene id: 52773:I6H42_RS04875
uniprot id: A0A1H1PCA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

52773:I6H42 RS03695
gene id: 52773:I6H42_RS03695
uniprot id: A0A1H1KQW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

52773:I6H42 RS02505
gene id: 52773:I6H42_RS02505
uniprot id: A0A1H1KTW1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

52773:I6H42 RS00435
gene id: 52773:I6H42_RS00435
uniprot id: A0A1H1LW00
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

52773:I6H42 RS05700
gene id: 52773:I6H42_RS05700
uniprot id: A0A1H1MF47
names: Similarity
messages: Belongs to the phosphohexose mutase family.

52773:I6H42 RS03270
gene id: 52773:I6H42_RS03270
uniprot id: A0A1H1KQV2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

52773:I6H42 RS03405
gene id: 52773:I6H42_RS03405
uniprot id: A0A1H1KRM9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

52773:I6H42 RS01285
gene id: 52773:I6H42_RS01285
uniprot id: A0A1H1L5C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

52773:I6H42 RS02355
gene id: 52773:I6H42_RS02355
uniprot id: A0A1H1KSG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

52773:I6H42 RS06005
gene id: 52773:I6H42_RS06005
uniprot id: A0A1H1MNG6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

52773:I6H42 RS01400
gene id: 52773:I6H42_RS01400
uniprot id: A0A1H1L3K6
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS02610
gene id: 52773:I6H42_RS02610
uniprot id: A0A1H1KSL8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

52773:I6H42 RS05995
gene id: 52773:I6H42_RS05995
uniprot id: A0A1H1MN95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

52773:I6H42 RS08935
gene id: 52773:I6H42_RS08935
uniprot id: A0A1H1LM55
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

52773:I6H42 RS07060
gene id: 52773:I6H42_RS07060
uniprot id: A0A1H1NCS8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

52773:I6H42 RS02495
gene id: 52773:I6H42_RS02495
uniprot id: A0A1H1KRZ5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

52773:I6H42 RS07700
gene id: 52773:I6H42_RS07700
uniprot id: A0A1H1Q4Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

52773:I6H42 RS00265
gene id: 52773:I6H42_RS00265
uniprot id: A0A1H1LST8
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

52773:I6H42 RS00510
gene id: 52773:I6H42_RS00510
uniprot id: A0A1H1NT30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

52773:I6H42 RS06850
gene id: 52773:I6H42_RS06850
uniprot id: A0A1H1N7W6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS02815
gene id: 52773:I6H42_RS02815
uniprot id: A0A1H1KRL3
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

52773:I6H42 RS05795
gene id: 52773:I6H42_RS05795
uniprot id: A0A1H1MHT7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

52773:I6H42 RS06795
gene id: 52773:I6H42_RS06795
uniprot id: A0A1H1N6X2
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS04335
gene id: 52773:I6H42_RS04335
uniprot id: A0A1H1KRW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

52773:I6H42 RS02770
gene id: 52773:I6H42_RS02770
uniprot id: A0A1H1KRN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

52773:I6H42 RS06380
gene id: 52773:I6H42_RS06380
uniprot id: A0A1H1MWM4
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

52773:I6H42 RS05955
gene id: 52773:I6H42_RS05955
uniprot id: A0A1H1MLY2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

52773:I6H42 RS02045
gene id: 52773:I6H42_RS02045
uniprot id: A0A1H1KR39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

52773:I6H42 RS06220
gene id: 52773:I6H42_RS06220
uniprot id: A0A1H1MTM7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

52773:I6H42 RS08955
gene id: 52773:I6H42_RS08955
uniprot id: A0A1H1LMH1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

52773:I6H42 RS04740
gene id: 52773:I6H42_RS04740
uniprot id: A0A1H1PDR1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52773:I6H42 RS04355
gene id: 52773:I6H42_RS04355
uniprot id: A0A1H1KQ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS03905
gene id: 52773:I6H42_RS03905
uniprot id: A0A1H1KRE8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

52773:I6H42 RS06180
gene id: 52773:I6H42_RS06180
uniprot id: A0A1H1MRY8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

52773:I6H42 RS05610
gene id: 52773:I6H42_RS05610
uniprot id: A0A1H1MD53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

52773:I6H42 RS04120
gene id: 52773:I6H42_RS04120
uniprot id: A0A1H1KRA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

52773:I6H42 RS05660
gene id: 52773:I6H42_RS05660
uniprot id: A0A1H1MFI0
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

52773:I6H42 RS02255
gene id: 52773:I6H42_RS02255
uniprot id: A0A1H1M2G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

52773:I6H42 RS06020
gene id: 52773:I6H42_RS06020
uniprot id: A0A1H1MNK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

52773:I6H42 RS06815
gene id: 52773:I6H42_RS06815
uniprot id: A0A1H1N714
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52773:I6H42 RS05865
gene id: 52773:I6H42_RS05865
uniprot id: A0A1H1MJJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

52773:I6H42 RS07760
gene id: 52773:I6H42_RS07760
uniprot id: A0A1H1Q3D3
names: Similarity
messages: Belongs to the UPF0225 family.

52773:I6H42 RS06450
gene id: 52773:I6H42_RS06450
uniprot id: A0A1H1MYX3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

52773:I6H42 RS05345
gene id: 52773:I6H42_RS05345
uniprot id: A0A1H1P0J3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

52773:I6H42 RS00320
gene id: 52773:I6H42_RS00320
uniprot id: A0A1H1LUX9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS06060
gene id: 52773:I6H42_RS06060
uniprot id: A0A1H1MPH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

52773:I6H42 RS01495
gene id: 52773:I6H42_RS01495
uniprot id: A0A1H1L2M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

52773:I6H42 RS04940
gene id: 52773:I6H42_RS04940
uniprot id: A0A1H1P973
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

52773:I6H42 RS05045
gene id: 52773:I6H42_RS05045
uniprot id: A0A1H1P6E4
names: Similarity
messages: Belongs to the GSP E family.

52773:I6H42 RS00260
gene id: 52773:I6H42_RS00260
uniprot id: A0A1H1LSW3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

52773:I6H42 RS08465
gene id: 52773:I6H42_RS08465
uniprot id: A0A1H1LAL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52773:I6H42 RS00540
gene id: 52773:I6H42_RS00540
uniprot id: A0A1H1NSU0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

52773:I6H42 RS02325
gene id: 52773:I6H42_RS02325
uniprot id: A0A1H1KSG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

52773:I6H42 RS03025
gene id: 52773:I6H42_RS03025
uniprot id: A0A1H1KRT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS01530
gene id: 52773:I6H42_RS01530
uniprot id: A0A1H1L3R9
names: Similarity
messages: Belongs to the peptidase S8 family.

52773:I6H42 RS00960
gene id: 52773:I6H42_RS00960
uniprot id: A0A1H1KWE8
names: Similarity
messages: Belongs to the LOG family.

52773:I6H42 RS03325
gene id: 52773:I6H42_RS03325
uniprot id: A0A1H1KRI8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

52773:I6H42 RS02425
gene id: 52773:I6H42_RS02425
uniprot id: A0A1H1KSH0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

52773:I6H42 RS05070
gene id: 52773:I6H42_RS05070
uniprot id: A0A1H1P5Z9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

52773:I6H42 RS08330
gene id: 52773:I6H42_RS08330
uniprot id: A0A1H1PNW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

52773:I6H42 RS05335
gene id: 52773:I6H42_RS05335
uniprot id: A0A1H1NZ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

52773:I6H42 RS05940
gene id: 52773:I6H42_RS05940
uniprot id: A0A1H1MLG2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS01015
gene id: 52773:I6H42_RS01015
uniprot id: A0A1H1KYE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS04065
gene id: 52773:I6H42_RS04065
uniprot id: A0A1H1KSA2
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

52773:I6H42 RS07200
gene id: 52773:I6H42_RS07200
uniprot id: A0A1H1NGE0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

52773:I6H42 RS03840
gene id: 52773:I6H42_RS03840
uniprot id: A0A1H1KR89
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS07515
gene id: 52773:I6H42_RS07515
uniprot id: A0A1H1KQN5
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS01755
gene id: 52773:I6H42_RS01755
uniprot id: A0A1H1KZV6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

52773:I6H42 RS07440
gene id: 52773:I6H42_RS07440
uniprot id: A0A1H1KQQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

52773:I6H42 RS04145
gene id: 52773:I6H42_RS04145
uniprot id: A0A1H1KS19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

52773:I6H42 RS06265
gene id: 52773:I6H42_RS06265
uniprot id: A0A1H1MU87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

52773:I6H42 RS05560
gene id: 52773:I6H42_RS05560
uniprot id: A0A1H1MCE8
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS03795
gene id: 52773:I6H42_RS03795
uniprot id: A0A1H1KQU8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

52773:I6H42 RS01560
gene id: 52773:I6H42_RS01560
uniprot id: A0A1H1L2D2
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS03925
gene id: 52773:I6H42_RS03925
uniprot id: A0A1H1KQS8
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS04175
gene id: 52773:I6H42_RS04175
uniprot id: A0A1H1KS83
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS02550
gene id: 52773:I6H42_RS02550
uniprot id: A0A1H1KSS2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.

52773:I6H42 RS04315
gene id: 52773:I6H42_RS04315
uniprot id: A0A1H1KQ90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

52773:I6H42 RS05705
gene id: 52773:I6H42_RS05705
uniprot id: A0A1H1MFA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

52773:I6H42 RS07145
gene id: 52773:I6H42_RS07145
uniprot id: A0A1H1NEY0
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS06230
gene id: 52773:I6H42_RS06230
uniprot id: A0A1H1MTJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

52773:I6H42 RS03195
gene id: 52773:I6H42_RS03195
uniprot id: A0A1H1KR46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

52773:I6H42 RS08470
gene id: 52773:I6H42_RS08470
uniprot id: A0A1H1LBU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

52773:I6H42 RS06120
gene id: 52773:I6H42_RS06120
uniprot id: A0A1H1MQT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

52773:I6H42 RS00535
gene id: 52773:I6H42_RS00535
uniprot id: A0A1H1NSF4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

52773:I6H42 RS02680
gene id: 52773:I6H42_RS02680
uniprot id: A0A1H1KTG7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

52773:I6H42 RS02205
gene id: 52773:I6H42_RS02205
uniprot id: A0A1H1M2D5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS00140
gene id: 52773:I6H42_RS00140
uniprot id: A0A1H1LQA6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

52773:I6H42 RS07730
gene id: 52773:I6H42_RS07730
uniprot id: A0A1H1Q3W4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

52773:I6H42 RS04375
gene id: 52773:I6H42_RS04375
uniprot id: A0A1H1KQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

52773:I6H42 RS06110
gene id: 52773:I6H42_RS06110
uniprot id: A0A1H1MT28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

52773:I6H42 RS02345
gene id: 52773:I6H42_RS02345
uniprot id: A0A1H1KSQ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

52773:I6H42 RS00290
gene id: 52773:I6H42_RS00290
uniprot id: A0A1H1LV08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

52773:I6H42 RS03540
gene id: 52773:I6H42_RS03540
uniprot id: A0A1H1KSD9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

52773:I6H42 RS03435
gene id: 52773:I6H42_RS03435
uniprot id: A0A1H1KR19
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS05310
gene id: 52773:I6H42_RS05310
uniprot id: A0A1H1NZY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

52773:I6H42 RS03200
gene id: 52773:I6H42_RS03200
uniprot id: A0A1H1KRR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS05720
gene id: 52773:I6H42_RS05720
uniprot id: A0A1H1MG03
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

52773:I6H42 RS03215
gene id: 52773:I6H42_RS03215
uniprot id: A0A1H1KSR7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

52773:I6H42 RS08085
gene id: 52773:I6H42_RS08085
uniprot id: A0A1H1PUV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

52773:I6H42 RS00325
gene id: 52773:I6H42_RS00325
uniprot id: A0A1H1LU45
names: Similarity
messages: Belongs to the UPF0234 family.

52773:I6H42 RS04210
gene id: 52773:I6H42_RS04210
uniprot id: A0A1H1KR68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

52773:I6H42 RS03705
gene id: 52773:I6H42_RS03705
uniprot id: A0A1H1KQV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

52773:I6H42 RS00460
gene id: 52773:I6H42_RS00460
uniprot id: A0A1H1LYL5
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS05530
gene id: 52773:I6H42_RS05530
uniprot id: A0A1H1MDJ0
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS06925
gene id: 52773:I6H42_RS06925
uniprot id: A0A1H1NBD3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

52773:I6H42 RS02660
gene id: 52773:I6H42_RS02660
uniprot id: A0A1H1KSH7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

52773:I6H42 RS07615
gene id: 52773:I6H42_RS07615
uniprot id: A0A1H1Q6B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS06415
gene id: 52773:I6H42_RS06415
uniprot id: A0A1H1MY88
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

52773:I6H42 RS04680
gene id: 52773:I6H42_RS04680
uniprot id: A0A1H1PF34
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

52773:I6H42 RS05730
gene id: 52773:I6H42_RS05730
uniprot id: A0A1H1MGA1
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS08920
gene id: 52773:I6H42_RS08920
uniprot id: A0A1H1LLW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

52773:I6H42 RS04840
gene id: 52773:I6H42_RS04840
uniprot id: A0A1H1PBA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

52773:I6H42 RS06335
gene id: 52773:I6H42_RS06335
uniprot id: A0A1H1MW24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

52773:I6H42 RS07340
gene id: 52773:I6H42_RS07340
uniprot id: A0A1H1NM27
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS06885
gene id: 52773:I6H42_RS06885
uniprot id: A0A1H1N8T4
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS05630
gene id: 52773:I6H42_RS05630
uniprot id: A0A1H1ME02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

52773:I6H42 RS05250
gene id: 52773:I6H42_RS05250
uniprot id: A0A1H1P1D4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

52773:I6H42 RS07985
gene id: 52773:I6H42_RS07985
uniprot id: A0A1H1PXY3
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

52773:I6H42 RS06080
gene id: 52773:I6H42_RS06080
uniprot id: A0A1H1MPW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

52773:I6H42 RS07860
gene id: 52773:I6H42_RS07860
uniprot id: A0A1H1Q245
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

52773:I6H42 RS05085
gene id: 52773:I6H42_RS05085
uniprot id: A0A1H1P5F9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

52773:I6H42 RS00475
gene id: 52773:I6H42_RS00475
uniprot id: A0A1H1LX43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

52773:I6H42 RS01735
gene id: 52773:I6H42_RS01735
uniprot id: A0A1H1L0Y5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

52773:I6H42 RS02615
gene id: 52773:I6H42_RS02615
uniprot id: A0A1H1KTD7
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

52773:I6H42 RS06210
gene id: 52773:I6H42_RS06210
uniprot id: A0A1H1MT94
names: Similarity
messages: Belongs to the peptidase C40 family.

52773:I6H42 RS07485
gene id: 52773:I6H42_RS07485
uniprot id: A0A1H1KPV4
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

52773:I6H42 RS02265
gene id: 52773:I6H42_RS02265
uniprot id: A0A1H1M286
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

52773:I6H42 RS02690
gene id: 52773:I6H42_RS02690
uniprot id: A0A1H1KRM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

52773:I6H42 RS03830
gene id: 52773:I6H42_RS03830
uniprot id: A0A1H1KSE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

52773:I6H42 RS06430
gene id: 52773:I6H42_RS06430
uniprot id: A0A1H1MXW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

52773:I6H42 RS04945
gene id: 52773:I6H42_RS04945
uniprot id: A0A1H1P8M1
names: Similarity
messages: Belongs to the UPF0145 family.

52773:I6H42 RS04230
gene id: 52773:I6H42_RS04230
uniprot id: A0A1H1KQC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

52773:I6H42 RS05770
gene id: 52773:I6H42_RS05770
uniprot id: A0A1H1MHF9
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

52773:I6H42 RS03720
gene id: 52773:I6H42_RS03720
uniprot id: A0A1H1KQK0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

52773:I6H42 RS05985
gene id: 52773:I6H42_RS05985
uniprot id: A0A1H1MMI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

52773:I6H42 RS08215
gene id: 52773:I6H42_RS08215
uniprot id: A0A1H1PRX4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS01290
gene id: 52773:I6H42_RS01290
uniprot id: A0A1H1L4K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

52773:I6H42 RS03445
gene id: 52773:I6H42_RS03445
uniprot id: A0A1H1KQZ8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

52773:I6H42 RS06145
gene id: 52773:I6H42_RS06145
uniprot id: A0A1H1MTU6
names: Similarity
messages: Belongs to the fructosamine kinase family.

52773:I6H42 RS04260
gene id: 52773:I6H42_RS04260
uniprot id: A0A1H1KR57
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

52773:I6H42 RS02040
gene id: 52773:I6H42_RS02040
uniprot id: A0A1H1KQD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

52773:I6H42 RS03165
gene id: 52773:I6H42_RS03165
uniprot id: A0A1H1KR23
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

52773:I6H42 RS01740
gene id: 52773:I6H42_RS01740
uniprot id: A0A1H1L0M4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

52773:I6H42 RS07585
gene id: 52773:I6H42_RS07585
uniprot id: A0A1H1Q7F7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

52773:I6H42 RS04540
gene id: 52773:I6H42_RS04540
uniprot id: A0A1H1KR32
names: Similarity
messages: Belongs to the peptidase M16 family.

52773:I6H42 RS01090
gene id: 52773:I6H42_RS01090
uniprot id: A0A1H1L9G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52773:I6H42 RS02360
gene id: 52773:I6H42_RS02360
uniprot id: A0A1H1KSD5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

52773:I6H42 RS01075
gene id: 52773:I6H42_RS01075
uniprot id: A0A1H1L808
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

52773:I6H42 RS07810
gene id: 52773:I6H42_RS07810
uniprot id: A0A1H1Q203
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS04790
gene id: 52773:I6H42_RS04790
uniprot id: A0A1H1PCT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

52773:I6H42 RS00765
gene id: 52773:I6H42_RS00765
uniprot id: A0A1H1KW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS04510
gene id: 52773:I6H42_RS04510
uniprot id: A0A1H1KQE1
names: Function
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.

52773:I6H42 RS02100
gene id: 52773:I6H42_RS02100
uniprot id: A0A1H1KQ72
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS08280
gene id: 52773:I6H42_RS08280
uniprot id: A0A1H1PPV4
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS07510
gene id: 52773:I6H42_RS07510
uniprot id: A0A1H1KQ78
names: Similarity
messages: Belongs to the LacAB/RpiB family.

52773:I6H42 RS03460
gene id: 52773:I6H42_RS03460
uniprot id: A0A1H1KQQ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

52773:I6H42 RS04445
gene id: 52773:I6H42_RS04445
uniprot id: A0A1H1KQ28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

52773:I6H42 RS02070
gene id: 52773:I6H42_RS02070
uniprot id: A0A1H1KQZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

52773:I6H42 RS06875
gene id: 52773:I6H42_RS06875
uniprot id: A0A1H1N8W7
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

52773:I6H42 RS07840
gene id: 52773:I6H42_RS07840
uniprot id: A0A1H1Q1D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS04435
gene id: 52773:I6H42_RS04435
uniprot id: A0A1H1KRY3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS04340
gene id: 52773:I6H42_RS04340
uniprot id: A0A1H1KQZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS06275
gene id: 52773:I6H42_RS06275
uniprot id: A0A1H1MWS3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

52773:I6H42 RS05750
gene id: 52773:I6H42_RS05750
uniprot id: A0A1H1MHX5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

52773:I6H42 RS01765
gene id: 52773:I6H42_RS01765
uniprot id: A0A1H1L1S5
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS03475
gene id: 52773:I6H42_RS03475
uniprot id: A0A1H1KQR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

52773:I6H42 RS03305
gene id: 52773:I6H42_RS03305
uniprot id: A0A1H1KQT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS05780
gene id: 52773:I6H42_RS05780
uniprot id: A0A1H1MHE6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

52773:I6H42 RS01645
gene id: 52773:I6H42_RS01645
uniprot id: A0A1H1L130
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

52773:I6H42 RS03245
gene id: 52773:I6H42_RS03245
uniprot id: A0A1H1KRQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS00630
gene id: 52773:I6H42_RS00630
uniprot id: A0A1H1KWC2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

52773:I6H42 RS00115
gene id: 52773:I6H42_RS00115
uniprot id: A0A1H1LR73
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS03845
gene id: 52773:I6H42_RS03845
uniprot id: A0A1H1KQT6
names: Similarity
messages: Belongs to the FemABX family.

52773:I6H42 RS06830
gene id: 52773:I6H42_RS06830
uniprot id: A0A1H1N7J4
names: Similarity
messages: Belongs to the thioredoxin family.

52773:I6H42 RS05300
gene id: 52773:I6H42_RS05300
uniprot id: A0A1H1P078
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

52773:I6H42 RS05820
gene id: 52773:I6H42_RS05820
uniprot id: A0A1H1MIU6
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

52773:I6H42 RS03050
gene id: 52773:I6H42_RS03050
uniprot id: A0A1H1KRS7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

52773:I6H42 RS04535
gene id: 52773:I6H42_RS04535
uniprot id: A0A1H1KS03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

52773:I6H42 RS08225
gene id: 52773:I6H42_RS08225
uniprot id: A0A1H1PRQ7
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

52773:I6H42 RS04785
gene id: 52773:I6H42_RS04785
uniprot id: A0A1H1PD67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

52773:I6H42 RS04490
gene id: 52773:I6H42_RS04490
uniprot id: A0A1H1KR21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

52773:I6H42 RS05735
gene id: 52773:I6H42_RS05735
uniprot id: A0A1H1MGU1
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS06325
gene id: 52773:I6H42_RS06325
uniprot id: A0A1H1MVV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

52773:I6H42 RS07920
gene id: 52773:I6H42_RS07920
uniprot id: A0A1H1PZ43
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS04930
gene id: 52773:I6H42_RS04930
uniprot id: A0A1H1P9C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS02400
gene id: 52773:I6H42_RS02400
uniprot id: A0A1H1KSD1
names: Similarity
messages: Belongs to the DtxR/MntR family.

52773:I6H42 RS07830
gene id: 52773:I6H42_RS07830
uniprot id: A0A1H1Q1C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

52773:I6H42 RS08200
gene id: 52773:I6H42_RS08200
uniprot id: A0A1H1PTH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

52773:I6H42 RS02830
gene id: 52773:I6H42_RS02830
uniprot id: A0A1H1KT97
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

52773:I6H42 RS01710
gene id: 52773:I6H42_RS01710
uniprot id: A0A1H1L069
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

52773:I6H42 RS08900
gene id: 52773:I6H42_RS08900
uniprot id: A0A1H1LLJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

52773:I6H42 RS07660
gene id: 52773:I6H42_RS07660
uniprot id: A0A1H1Q5A6
names: Similarity
messages: Belongs to the ParB family.

52773:I6H42 RS03400
gene id: 52773:I6H42_RS03400
uniprot id: A0A1H1KQX1
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

52773:I6H42 RS02055
gene id: 52773:I6H42_RS02055
uniprot id: A0A1H1KR60
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS05970
gene id: 52773:I6H42_RS05970
uniprot id: A0A1H1MPI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

52773:I6H42 RS04705
gene id: 52773:I6H42_RS04705
uniprot id: A0A1H1PDX2
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

52773:I6H42 RS08265
gene id: 52773:I6H42_RS08265
uniprot id: A0A1H1PQR4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

52773:I6H42 RS08020
gene id: 52773:I6H42_RS08020
uniprot id: A0A1H1PWU0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52773:I6H42 RS07430
gene id: 52773:I6H42_RS07430
uniprot id: A0A1H1KQT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Cytoplasm
messages: Homotetramer.

52773:I6H42 RS01690
gene id: 52773:I6H42_RS01690
uniprot id: A0A1H1L196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52773:I6H42 RS06510
gene id: 52773:I6H42_RS06510
uniprot id: A0A1H1N0A6
names: Similarity
messages: Belongs to the peptidase M18 family.

52773:I6H42 RS06890
gene id: 52773:I6H42_RS06890
uniprot id: A0A1H1N8P2
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS05670
gene id: 52773:I6H42_RS05670
uniprot id: A0A1H1MGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

52773:I6H42 RS08120
gene id: 52773:I6H42_RS08120
uniprot id: A0A1H1PU40
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS05550
gene id: 52773:I6H42_RS05550
uniprot id: A0A1H1MC79
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

52773:I6H42 RS07705
gene id: 52773:I6H42_RS07705
uniprot id: A0A1H1Q471
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

52773:I6H42 RS02765
gene id: 52773:I6H42_RS02765
uniprot id: A0A1H1KRQ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS03315
gene id: 52773:I6H42_RS03315
uniprot id: A0A1H1KSP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

52773:I6H42 RS03395
gene id: 52773:I6H42_RS03395
uniprot id: A0A1H1KR06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

52773:I6H42 RS04660
gene id: 52773:I6H42_RS04660
uniprot id: A0A1H1PFP8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

52773:I6H42 RS01405
gene id: 52773:I6H42_RS01405
uniprot id: A0A1H1L3E8
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS04615
gene id: 52773:I6H42_RS04615
uniprot id: A0A1H1KQF9
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

52773:I6H42 RS08455
gene id: 52773:I6H42_RS08455
uniprot id: A0A1H1LAQ1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

52773:I6H42 RS08140
gene id: 52773:I6H42_RS08140
uniprot id: A0A1H1PTY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

52773:I6H42 RS03320
gene id: 52773:I6H42_RS03320
uniprot id: A0A1H1KQU0
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS05140
gene id: 52773:I6H42_RS05140
uniprot id: A0A1H1P5Q4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

52773:I6H42 RS00610
gene id: 52773:I6H42_RS00610
uniprot id: A0A1H1KU87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS04360
gene id: 52773:I6H42_RS04360
uniprot id: A0A1H1KQA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

52773:I6H42 RS03725
gene id: 52773:I6H42_RS03725
uniprot id: A0A1H1KRI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

52773:I6H42 RS02540
gene id: 52773:I6H42_RS02540
uniprot id: A0A1H1KTS0
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS05390
gene id: 52773:I6H42_RS05390
uniprot id: A0A1H1KRK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

52773:I6H42 RS03515
gene id: 52773:I6H42_RS03515
uniprot id: A0A1H1KRM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

52773:I6H42 RS03235
gene id: 52773:I6H42_RS03235
uniprot id: A0A1H1KR36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

52773:I6H42 RS06950
gene id: 52773:I6H42_RS06950
uniprot id: A0A1H1NAR2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

52773:I6H42 RS07710
gene id: 52773:I6H42_RS07710
uniprot id: A0A1H1Q425
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

52773:I6H42 RS05440
gene id: 52773:I6H42_RS05440
uniprot id: A0A1H1KRL9
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS08115
gene id: 52773:I6H42_RS08115
uniprot id: A0A1H1PTL3
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

52773:I6H42 RS07825
gene id: 52773:I6H42_RS07825
uniprot id: A0A1H1Q235
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

52773:I6H42 RS03255
gene id: 52773:I6H42_RS03255
uniprot id: A0A1H1KRS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

52773:I6H42 RS02950
gene id: 52773:I6H42_RS02950
uniprot id: A0A1H1KSX1
names: Similarity
messages: Belongs to the TlyA family.

52773:I6H42 RS08445
gene id: 52773:I6H42_RS08445
uniprot id: A0A1H1LAP0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

52773:I6H42 RS04745
gene id: 52773:I6H42_RS04745
uniprot id: A0A1H1PD83
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS02900
gene id: 52773:I6H42_RS02900
uniprot id: A0A1H1KSZ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS06095
gene id: 52773:I6H42_RS06095
uniprot id: A0A1H1MQF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

52773:I6H42 RS05165
gene id: 52773:I6H42_RS05165
uniprot id: A0A1H1P3C0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS01640
gene id: 52773:I6H42_RS01640
uniprot id: A0A1H1L0W6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

52773:I6H42 RS03535
gene id: 52773:I6H42_RS03535
uniprot id: A0A1H1KQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

52773:I6H42 RS04090
gene id: 52773:I6H42_RS04090
uniprot id: A0A1H1KQM9
names: Similarity
messages: Belongs to the peptidase M13 family.

52773:I6H42 RS02685
gene id: 52773:I6H42_RS02685
uniprot id: A0A1H1KS91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

52773:I6H42 RS07270
gene id: 52773:I6H42_RS07270
uniprot id: A0A1H1NI47
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

52773:I6H42 RS00680
gene id: 52773:I6H42_RS00680
uniprot id: A0A1H1KUS2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

52773:I6H42 RS03210
gene id: 52773:I6H42_RS03210
uniprot id: A0A1H1KRT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

52773:I6H42 RS00635
gene id: 52773:I6H42_RS00635
uniprot id: A0A1H1KUH0
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS06035
gene id: 52773:I6H42_RS06035
uniprot id: A0A1H1MNV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

52773:I6H42 RS07815
gene id: 52773:I6H42_RS07815
uniprot id: A0A1H1Q1V2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

52773:I6H42 RS04915
gene id: 52773:I6H42_RS04915
uniprot id: A0A1H1P9F5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

52773:I6H42 RS00470
gene id: 52773:I6H42_RS00470
uniprot id: A0A1H1LWY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

52773:I6H42 RS03920
gene id: 52773:I6H42_RS03920
uniprot id: A0A1H1KR81
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

52773:I6H42 RS00650
gene id: 52773:I6H42_RS00650
uniprot id: A0A1H1KUM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

52773:I6H42 RS00255
gene id: 52773:I6H42_RS00255
uniprot id: A0A1H1LU32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

52773:I6H42 RS07015
gene id: 52773:I6H42_RS07015
uniprot id: A0A1H1NBX5
names: Similarity
messages: Belongs to the GSP E family.

52773:I6H42 RS07010
gene id: 52773:I6H42_RS07010
uniprot id: A0A1H1NCE3
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS04025
gene id: 52773:I6H42_RS04025
uniprot id: A0A1H1KR62
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

52773:I6H42 RS02835
gene id: 52773:I6H42_RS02835
uniprot id: A0A1H1KRM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

52773:I6H42 RS02030
gene id: 52773:I6H42_RS02030
uniprot id: A0A1H1KRX9
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS07575
gene id: 52773:I6H42_RS07575
uniprot id: A0A1H1Q977
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

52773:I6H42 RS06790
gene id: 52773:I6H42_RS06790
uniprot id: A0A1H1N6T3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS07475
gene id: 52773:I6H42_RS07475
uniprot id: A0A1H1KRR9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

52773:I6H42 RS02995
gene id: 52773:I6H42_RS02995
uniprot id: A0A1H1KS14
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

52773:I6H42 RS06810
gene id: 52773:I6H42_RS06810
uniprot id: A0A1H1N6W8
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS00790
gene id: 52773:I6H42_RS00790
uniprot id: A0A1H1KW99
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

52773:I6H42 RS04880
gene id: 52773:I6H42_RS04880
uniprot id: A0A1H1PAZ4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

52773:I6H42 RS04015
gene id: 52773:I6H42_RS04015
uniprot id: A0A1H1KSB1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

52773:I6H42 RS02365
gene id: 52773:I6H42_RS02365
uniprot id: A0A1H1KTA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS04985
gene id: 52773:I6H42_RS04985
uniprot id: A0A1H1P7P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

52773:I6H42 RS00185
gene id: 52773:I6H42_RS00185
uniprot id: A0A1H1LRM9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

52773:I6H42 RS02290
gene id: 52773:I6H42_RS02290
uniprot id: A0A1H1M2L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

52773:I6H42 RS06100
gene id: 52773:I6H42_RS06100
uniprot id: A0A1H1MQS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

52773:I6H42 RS00775
gene id: 52773:I6H42_RS00775
uniprot id: A0A1H1KVU5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

52773:I6H42 RS07550
gene id: 52773:I6H42_RS07550
uniprot id: A0A1H1KQ69
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS00195
gene id: 52773:I6H42_RS00195
uniprot id: A0A1H1LR89
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

52773:I6H42 RS05760
gene id: 52773:I6H42_RS05760
uniprot id: A0A1H1MH40
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

52773:I6H42 RS03020
gene id: 52773:I6H42_RS03020
uniprot id: A0A1H1KS21
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS03355
gene id: 52773:I6H42_RS03355
uniprot id: A0A1H1KQS0
names: Similarity
messages: Belongs to the UPF0749 family.

52773:I6H42 RS02270
gene id: 52773:I6H42_RS02270
uniprot id: A0A1H1M0X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

52773:I6H42 RS07680
gene id: 52773:I6H42_RS07680
uniprot id: A0A1H1Q575
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

52773:I6H42 RS08540
gene id: 52773:I6H42_RS08540
uniprot id: A0A1H1LHR6
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS02735
gene id: 52773:I6H42_RS02735
uniprot id: A0A1H1KTD6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS05870
gene id: 52773:I6H42_RS05870
uniprot id: A0A1H1MKT7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

52773:I6H42 RS08835
gene id: 52773:I6H42_RS08835
uniprot id: A0A1H1LKF7
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

52773:I6H42 RS06270
gene id: 52773:I6H42_RS06270
uniprot id: A0A1H1MV90
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

52773:I6H42 RS07520
gene id: 52773:I6H42_RS07520
uniprot id: A0A1H1KPX9
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS04525
gene id: 52773:I6H42_RS04525
uniprot id: A0A1H1KQW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

52773:I6H42 RS02065
gene id: 52773:I6H42_RS02065
uniprot id: A0A1H1KQ89
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS05910
gene id: 52773:I6H42_RS05910
uniprot id: A0A1H1ML17
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

52773:I6H42 RS07140
gene id: 52773:I6H42_RS07140
uniprot id: A0A1H1NF96
names: Similarity
messages: Belongs to the CsoR family.

52773:I6H42 RS07225
gene id: 52773:I6H42_RS07225
uniprot id: A0A1H1NHB5
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS07765
gene id: 52773:I6H42_RS07765
uniprot id: A0A1H1Q332
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

52773:I6H42 RS04715
gene id: 52773:I6H42_RS04715
uniprot id: A0A1H1PDV4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

52773:I6H42 RS00275
gene id: 52773:I6H42_RS00275
uniprot id: A0A1H1LTA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

52773:I6H42 RS02010
gene id: 52773:I6H42_RS02010
uniprot id: A0A1H1KS49
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS00365
gene id: 52773:I6H42_RS00365
uniprot id: A0A1H1LWB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS01375
gene id: 52773:I6H42_RS01375
uniprot id: A0A1H1L3Y2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

52773:I6H42 RS08770
gene id: 52773:I6H42_RS08770
uniprot id: A0A1H1LJI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

52773:I6H42 RS04830
gene id: 52773:I6H42_RS04830
uniprot id: A0A1H1PBQ0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

52773:I6H42 RS00940
gene id: 52773:I6H42_RS00940
uniprot id: A0A1H1KXM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

52773:I6H42 RS08845
gene id: 52773:I6H42_RS08845
uniprot id: A0A1H1LKW1
names: Similarity
messages: Belongs to the UPF0423 family.

52773:I6H42 RS00700
gene id: 52773:I6H42_RS00700
uniprot id: A0A1H1KV43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

52773:I6H42 RS04920
gene id: 52773:I6H42_RS04920
uniprot id: A0A1H1PA32
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

52773:I6H42 RS04325
gene id: 52773:I6H42_RS04325
uniprot id: A0A1H1KQS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

52773:I6H42 RS00440
gene id: 52773:I6H42_RS00440
uniprot id: A0A1H1LW39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

52773:I6H42 RS08855
gene id: 52773:I6H42_RS08855
uniprot id: A0A1H1LML1
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS02665
gene id: 52773:I6H42_RS02665
uniprot id: A0A1H1KTH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

52773:I6H42 RS00500
gene id: 52773:I6H42_RS00500
uniprot id: A0A1H1LXG1
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS01895
gene id: 52773:I6H42_RS01895
uniprot id: A0A1H1KYA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

52773:I6H42 RS01535
gene id: 52773:I6H42_RS01535
uniprot id: A0A1H1L3N5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

52773:I6H42 RS02300
gene id: 52773:I6H42_RS02300
uniprot id: A0A1H1KSP3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

52773:I6H42 RS00660
gene id: 52773:I6H42_RS00660
uniprot id: A0A1H1KUL0
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS01725
gene id: 52773:I6H42_RS01725
uniprot id: A0A1H1L106
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS00300
gene id: 52773:I6H42_RS00300
uniprot id: A0A1H1LVY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

52773:I6H42 RS08655
gene id: 52773:I6H42_RS08655
uniprot id: A0A1H1LJF1
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

52773:I6H42 RS04610
gene id: 52773:I6H42_RS04610
uniprot id: A0A1H1KQC0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

52773:I6H42 RS06760
gene id: 52773:I6H42_RS06760
uniprot id: A0A1H1N6H6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52773:I6H42 RS04265
gene id: 52773:I6H42_RS04265
uniprot id: A0A1H1KQ98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

52773:I6H42 RS08860
gene id: 52773:I6H42_RS08860
uniprot id: A0A1H1LM62
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS07650
gene id: 52773:I6H42_RS07650
uniprot id: A0A1H1Q5J7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

52773:I6H42 RS03465
gene id: 52773:I6H42_RS03465
uniprot id: A0A1H1KRN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

52773:I6H42 RS00145
gene id: 52773:I6H42_RS00145
uniprot id: A0A1H1LQ59
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS01770
gene id: 52773:I6H42_RS01770
uniprot id: A0A1H1KZR7
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

52773:I6H42 RS03740
gene id: 52773:I6H42_RS03740
uniprot id: A0A1H1KRB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

52773:I6H42 RS03495
gene id: 52773:I6H42_RS03495
uniprot id: A0A1H1KQY8
names: Similarity
messages: Belongs to the glutamine synthetase family.

52773:I6H42 RS07900
gene id: 52773:I6H42_RS07900
uniprot id: A0A1H1PZW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

52773:I6H42 RS04185
gene id: 52773:I6H42_RS04185
uniprot id: A0A1H1KR30
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

52773:I6H42 RS05875
gene id: 52773:I6H42_RS05875
uniprot id: A0A1H1MK78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

52773:I6H42 RS05320
gene id: 52773:I6H42_RS05320
uniprot id: A0A1H1P1C0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS06250
gene id: 52773:I6H42_RS06250
uniprot id: A0A1H1MW96
names: Similarity
messages: Belongs to the PspA/IM30 family.

52773:I6H42 RS03045
gene id: 52773:I6H42_RS03045
uniprot id: A0A1H1KSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS05130
gene id: 52773:I6H42_RS05130
uniprot id: A0A1H1P4W1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

52773:I6H42 RS03175
gene id: 52773:I6H42_RS03175
uniprot id: A0A1H1KSS8
names: Similarity
messages: Belongs to the prokaryotic ubiquitin-like protein family.

52773:I6H42 RS01185
gene id: 52773:I6H42_RS01185
uniprot id: A0A1H1L6Z2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52773:I6H42 RS03490
gene id: 52773:I6H42_RS03490
uniprot id: A0A1H1KSF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

52773:I6H42 RS02410
gene id: 52773:I6H42_RS02410
uniprot id: A0A1H1KS79
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS06070
gene id: 52773:I6H42_RS06070
uniprot id: A0A1H1MS77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

52773:I6H42 RS02350
gene id: 52773:I6H42_RS02350
uniprot id: A0A1H1KSD7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

52773:I6H42 RS05825
gene id: 52773:I6H42_RS05825
uniprot id: A0A1H1MIA2
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS06010
gene id: 52773:I6H42_RS06010
uniprot id: A0A1H1MQK3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

52773:I6H42 RS05855
gene id: 52773:I6H42_RS05855
uniprot id: A0A1H1MJ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

52773:I6H42 RS00605
gene id: 52773:I6H42_RS00605
uniprot id: A0A1H1KV95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS06920
gene id: 52773:I6H42_RS06920
uniprot id: A0A1H1N9R9
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

52773:I6H42 RS00240
gene id: 52773:I6H42_RS00240
uniprot id: A0A1H1LSH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

52773:I6H42 RS01900
gene id: 52773:I6H42_RS01900
uniprot id: A0A1H1KXV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

52773:I6H42 RS08475
gene id: 52773:I6H42_RS08475
uniprot id: A0A1H1LAZ5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

52773:I6H42 RS00405
gene id: 52773:I6H42_RS00405
uniprot id: A0A1H1LVA9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

52773:I6H42 RS04865
gene id: 52773:I6H42_RS04865
uniprot id: A0A1H1PAK5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

52773:I6H42 RS00245
gene id: 52773:I6H42_RS00245
uniprot id: A0A1H1LTX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

52773:I6H42 RS04965
gene id: 52773:I6H42_RS04965
uniprot id: A0A1H1P8D8
names: Similarity
messages: Belongs to the CsoR family.

52773:I6H42 RS02875
gene id: 52773:I6H42_RS02875
uniprot id: A0A1H1KRA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

52773:I6H42 RS08715
gene id: 52773:I6H42_RS08715
uniprot id: A0A1H1LJ32
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

52773:I6H42 RS06670
gene id: 52773:I6H42_RS06670
uniprot id: A0A1H1N471
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS04845
gene id: 52773:I6H42_RS04845
uniprot id: A0A1H1PD24
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

52773:I6H42 RS08625
gene id: 52773:I6H42_RS08625
uniprot id: A0A1H1LH82
names: Similarity
messages: Belongs to the Dps family.

52773:I6H42 RS01685
gene id: 52773:I6H42_RS01685
uniprot id: A0A1H1L0E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

52773:I6H42 RS07695
gene id: 52773:I6H42_RS07695
uniprot id: A0A1H1Q5U6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

52773:I6H42 RS04580
gene id: 52773:I6H42_RS04580
uniprot id: A0A1H1KQX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

52773:I6H42 RS06240
gene id: 52773:I6H42_RS06240
uniprot id: A0A1H1MTT3
names: Subcellular Location Annotation
messages: Cytoplasm

52773:I6H42 RS01565
gene id: 52773:I6H42_RS01565
uniprot id: A0A1H1L3A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

52773:I6H42 RS05000
gene id: 52773:I6H42_RS05000
uniprot id: A0A1H1P822
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

52773:I6H42 RS02795
gene id: 52773:I6H42_RS02795
uniprot id: A0A1H1KRI6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

52773:I6H42 RS05240
gene id: 52773:I6H42_RS05240
uniprot id: A0A1H1P1K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52773:I6H42 RS08925
gene id: 52773:I6H42_RS08925
uniprot id: A0A1H1LM00
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

52773:I6H42 RS03240
gene id: 52773:I6H42_RS03240
uniprot id: A0A1H1KR01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

52773:I6H42 RS00065
gene id: 52773:I6H42_RS00065
uniprot id: A0A1H1LQN9
names: Similarity
messages: Belongs to the WXG100 family.

52773:I6H42 RS04160
gene id: 52773:I6H42_RS04160
uniprot id: A0A1H1KR79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

52773:I6H42 RS02650
gene id: 52773:I6H42_RS02650
uniprot id: A0A1H1KRK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

52773:I6H42 RS02885
gene id: 52773:I6H42_RS02885
uniprot id: A0A1H1KRI3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

52773:I6H42 RS03620
gene id: 52773:I6H42_RS03620
uniprot id: A0A1H1KQM1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

52773:I6H42 RS03550
gene id: 52773:I6H42_RS03550
uniprot id: A0A1H1KQU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

52773:I6H42 RS01800
gene id: 52773:I6H42_RS01800
uniprot id: A0A1H1KYC0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

52773:I6H42 RS02250
gene id: 52773:I6H42_RS02250
uniprot id: A0A1H1M174
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

52773:I6H42 RS01025
gene id: 52773:I6H42_RS01025
uniprot id: A0A1H1KXI8
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

52773:I6H42 RS05745
gene id: 52773:I6H42_RS05745
uniprot id: A0A1H1MHR5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

52773:I6H42 RS06025
gene id: 52773:I6H42_RS06025
uniprot id: A0A1H1MPP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

52773:I6H42 RS03730
gene id: 52773:I6H42_RS03730
uniprot id: A0A1H1KSG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

52773:I6H42 RS01230
gene id: 52773:I6H42_RS01230
uniprot id: A0A1H1L5U4
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS00855
gene id: 52773:I6H42_RS00855
uniprot id: A0A1H1KWM7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

52773:I6H42 RS08605
gene id: 52773:I6H42_RS08605
uniprot id: A0A1H1LHH5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

52773:I6H42 RS00285
gene id: 52773:I6H42_RS00285
uniprot id: A0A1H1LTD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

52773:I6H42 RS03345
gene id: 52773:I6H42_RS03345
uniprot id: A0A1H1KQY2
names: Similarity
messages: Belongs to the UPF0749 family.

52773:I6H42 RS02025
gene id: 52773:I6H42_RS02025
uniprot id: A0A1H1KQJ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

52773:I6H42 RS03975
gene id: 52773:I6H42_RS03975
uniprot id: A0A1H1KQR8
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

52773:I6H42 RS00370
gene id: 52773:I6H42_RS00370
uniprot id: A0A1H1LX29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52773:I6H42 RS01790
gene id: 52773:I6H42_RS01790
uniprot id: A0A1H1KYL7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

52773:I6H42 RS00565
gene id: 52773:I6H42_RS00565
uniprot id: A0A1H1NRT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS08665
gene id: 52773:I6H42_RS08665
uniprot id: A0A1H1LI98
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

52773:I6H42 RS06065
gene id: 52773:I6H42_RS06065
uniprot id: A0A1H1MPL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

52773:I6H42 RS06075
gene id: 52773:I6H42_RS06075
uniprot id: A0A1H1MPX2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

52773:I6H42 RS05980
gene id: 52773:I6H42_RS05980
uniprot id: A0A1H1MM84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

52773:I6H42 RS06125
gene id: 52773:I6H42_RS06125
uniprot id: A0A1H1MTF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

52773:I6H42 RS00205
gene id: 52773:I6H42_RS00205
uniprot id: A0A1H1LRG7
names: Similarity
messages: Belongs to the peptidase S1C family.

52773:I6H42 RS05410
gene id: 52773:I6H42_RS05410
uniprot id: A0A1H1KRU6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

52773:I6H42 RS04245
gene id: 52773:I6H42_RS04245
uniprot id: A0A1H1KRZ7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

52773:I6H42 RS03790
gene id: 52773:I6H42_RS03790
uniprot id: A0A1H1KR98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

52773:I6H42 RS02415
gene id: 52773:I6H42_RS02415
uniprot id: A0A1H1KSI0
names: Similarity
messages: Belongs to the FPG family.

52773:I6H42 RS06475
gene id: 52773:I6H42_RS06475
uniprot id: A0A1H1MZ66
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

52773:I6H42 RS04925
gene id: 52773:I6H42_RS04925
uniprot id: A0A1H1P9L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS01655
gene id: 52773:I6H42_RS01655
uniprot id: A0A1H1L1L4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

52773:I6H42 RS06605
gene id: 52773:I6H42_RS06605
uniprot id: A0A1H1N277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane

52773:I6H42 RS05930
gene id: 52773:I6H42_RS05930
uniprot id: A0A1H1MLJ0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

52773:I6H42 RS05965
gene id: 52773:I6H42_RS05965
uniprot id: A0A1H1MMB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

52773:I6H42 RS08075
gene id: 52773:I6H42_RS08075
uniprot id: A0A1H1PV23
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS03030
gene id: 52773:I6H42_RS03030
uniprot id: A0A1H1KST4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

52773:I6H42 RS07025
gene id: 52773:I6H42_RS07025
uniprot id: A0A1H1NCE5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

52773:I6H42 RS01360
gene id: 52773:I6H42_RS01360
uniprot id: A0A1H1L5S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

52773:I6H42 RS05010
gene id: 52773:I6H42_RS05010
uniprot id: A0A1H1P7J8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

52773:I6H42 RS08705
gene id: 52773:I6H42_RS08705
uniprot id: A0A1H1LIX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS08635
gene id: 52773:I6H42_RS08635
uniprot id: A0A1H1LH51
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS00690
gene id: 52773:I6H42_RS00690
uniprot id: A0A1H1KV23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

52773:I6H42 RS08275
gene id: 52773:I6H42_RS08275
uniprot id: A0A1H1PQ07
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

52773:I6H42 RS04430
gene id: 52773:I6H42_RS04430
uniprot id: A0A1H1KQ42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

52773:I6H42 RS06215
gene id: 52773:I6H42_RS06215
uniprot id: A0A1H1MSK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

52773:I6H42 RS03735
gene id: 52773:I6H42_RS03735
uniprot id: A0A1H1KQL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

52773:I6H42 RS04165
gene id: 52773:I6H42_RS04165
uniprot id: A0A1H1KQB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

52773:I6H42 RS00975
gene id: 52773:I6H42_RS00975
uniprot id: A0A1H1KY62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

52773:I6H42 RS07670
gene id: 52773:I6H42_RS07670
uniprot id: A0A1H1Q5S7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.

52773:I6H42 RS05840
gene id: 52773:I6H42_RS05840
uniprot id: A0A1H1ML84
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

52773:I6H42 RS02435
gene id: 52773:I6H42_RS02435
uniprot id: A0A1H1KT29
names: Similarity
messages: Belongs to the IMPACT family.

52773:I6H42 RS04095
gene id: 52773:I6H42_RS04095
uniprot id: A0A1H1KQI9
names: Similarity
messages: Belongs to the peptidase M1 family.

52773:I6H42 RS00415
gene id: 52773:I6H42_RS00415
uniprot id: A0A1H1LXT8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

52773:I6H42 RS03455
gene id: 52773:I6H42_RS03455
uniprot id: A0A1H1KRL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

52773:I6H42 RS04455
gene id: 52773:I6H42_RS04455
uniprot id: A0A1H1KQ88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS04545
gene id: 52773:I6H42_RS04545
uniprot id: A0A1H1KQ47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

52773:I6H42 RS00170
gene id: 52773:I6H42_RS00170
uniprot id: A0A1H1LR11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

52773:I6H42 RS07500
gene id: 52773:I6H42_RS07500
uniprot id: A0A1H1KQ59
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

52773:I6H42 RS03630
gene id: 52773:I6H42_RS03630
uniprot id: A0A1H1KSI8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

52773:I6H42 RS01930
gene id: 52773:I6H42_RS01930
uniprot id: A0A1H1KXS9
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS05990
gene id: 52773:I6H42_RS05990
uniprot id: A0A1H1MME4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

52773:I6H42 RS06840
gene id: 52773:I6H42_RS06840
uniprot id: A0A1H1N7X4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

52773:I6H42 RS05710
gene id: 52773:I6H42_RS05710
uniprot id: A0A1H1MHZ8
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

52773:I6H42 RS06935
gene id: 52773:I6H42_RS06935
uniprot id: A0A1H1N9P7
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS05110
gene id: 52773:I6H42_RS05110
uniprot id: A0A1H1P594
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

52773:I6H42 RS03530
gene id: 52773:I6H42_RS03530
uniprot id: A0A1H1KRE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

52773:I6H42 RS03600
gene id: 52773:I6H42_RS03600
uniprot id: A0A1H1KSD0
names: Similarity
messages: Belongs to the peptidase A24 family.

52773:I6H42 RS04420
gene id: 52773:I6H42_RS04420
uniprot id: A0A1H1KQD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

52773:I6H42 RS07470
gene id: 52773:I6H42_RS07470
uniprot id: A0A1H1KPX1
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS02880
gene id: 52773:I6H42_RS02880
uniprot id: A0A1H1KRK4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

52773:I6H42 RS08535
gene id: 52773:I6H42_RS08535
uniprot id: A0A1H1LHP2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

52773:I6H42 RS04070
gene id: 52773:I6H42_RS04070
uniprot id: A0A1H1KQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

52773:I6H42 RS03625
gene id: 52773:I6H42_RS03625
uniprot id: A0A1H1KRK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

52773:I6H42 RS08310
gene id: 52773:I6H42_RS08310
uniprot id: A0A1H1PPD4
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS04135
gene id: 52773:I6H42_RS04135
uniprot id: A0A1H1KR42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

52773:I6H42 RS06750
gene id: 52773:I6H42_RS06750
uniprot id: A0A1H1N5K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

52773:I6H42 RS04895
gene id: 52773:I6H42_RS04895
uniprot id: A0A1H1PA23
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS05185
gene id: 52773:I6H42_RS05185
uniprot id: A0A1H1P398
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

52773:I6H42 RS08070
gene id: 52773:I6H42_RS08070
uniprot id: A0A1H1PVH4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

52773:I6H42 RS04485
gene id: 52773:I6H42_RS04485
uniprot id: A0A1H1KRZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

52773:I6H42 RS06385
gene id: 52773:I6H42_RS06385
uniprot id: A0A1H1MXA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

52773:I6H42 RS05040
gene id: 52773:I6H42_RS05040
uniprot id: A0A1H1P6Q7
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS05135
gene id: 52773:I6H42_RS05135
uniprot id: A0A1H1P443
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

52773:I6H42 RS05415
gene id: 52773:I6H42_RS05415
uniprot id: A0A1H1KQX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

52773:I6H42 RS07690
gene id: 52773:I6H42_RS07690
uniprot id: A0A1H1Q4Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

52773:I6H42 RS02790
gene id: 52773:I6H42_RS02790
uniprot id: A0A1H1KRP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

52773:I6H42 RS01850
gene id: 52773:I6H42_RS01850
uniprot id: A0A1H1KY50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

52773:I6H42 RS06660
gene id: 52773:I6H42_RS06660
uniprot id: A0A1H1N4E0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

52773:I6H42 RS08260
gene id: 52773:I6H42_RS08260
uniprot id: A0A1H1PQU4
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS06280
gene id: 52773:I6H42_RS06280
uniprot id: A0A1H1MV04
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

52773:I6H42 RS02745
gene id: 52773:I6H42_RS02745
uniprot id: A0A1H1KRR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

52773:I6H42 RS03775
gene id: 52773:I6H42_RS03775
uniprot id: A0A1H1KRH0
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS02340
gene id: 52773:I6H42_RS02340
uniprot id: A0A1H1KTD2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

52773:I6H42 RS02275
gene id: 52773:I6H42_RS02275
uniprot id: A0A1H1M0Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

52773:I6H42 RS05715
gene id: 52773:I6H42_RS05715
uniprot id: A0A1H1MGX4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

52773:I6H42 RS05035
gene id: 52773:I6H42_RS05035
uniprot id: A0A1H1P6Z8
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS06400
gene id: 52773:I6H42_RS06400
uniprot id: A0A1H1MX20
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS08550
gene id: 52773:I6H42_RS08550
uniprot id: A0A1H1LG30
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

52773:I6H42 RS04020
gene id: 52773:I6H42_RS04020
uniprot id: A0A1H1KQG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

52773:I6H42 RS04380
gene id: 52773:I6H42_RS04380
uniprot id: A0A1H1KQ32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

52773:I6H42 RS00825
gene id: 52773:I6H42_RS00825
uniprot id: A0A1H1KVN7
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS00315
gene id: 52773:I6H42_RS00315
uniprot id: A0A1H1LVL2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

52773:I6H42 RS00190
gene id: 52773:I6H42_RS00190
uniprot id: A0A1H1LRJ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS00295
gene id: 52773:I6H42_RS00295
uniprot id: A0A1H1LU87
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS02750
gene id: 52773:I6H42_RS02750
uniprot id: A0A1H1KRP6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

52773:I6H42 RS08930
gene id: 52773:I6H42_RS08930
uniprot id: A0A1H1LMH0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

52773:I6H42 RS02220
gene id: 52773:I6H42_RS02220
uniprot id: A0A1H1M2B3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

52773:I6H42 RS05385
gene id: 52773:I6H42_RS05385
uniprot id: A0A1H1KQ75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

52773:I6H42 RS03280
gene id: 52773:I6H42_RS03280
uniprot id: A0A1H1KR45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52773:I6H42 RS05935
gene id: 52773:I6H42_RS05935
uniprot id: A0A1H1ML89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

52773:I6H42 RS02725
gene id: 52773:I6H42_RS02725
uniprot id: A0A1H1KRL1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

52773:I6H42 RS00390
gene id: 52773:I6H42_RS00390
uniprot id: A0A1H1LVB8
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

52773:I6H42 RS00215
gene id: 52773:I6H42_RS00215
uniprot id: A0A1H1LSG6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

52773:I6H42 RS04290
gene id: 52773:I6H42_RS04290
uniprot id: A0A1H1KQK3
names: Subcellular Location Annotation
messages: Cytoplasm

52773:I6H42 RS06130
gene id: 52773:I6H42_RS06130
uniprot id: A0A1H1MR24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

52773:I6H42 RS04505
gene id: 52773:I6H42_RS04505
uniprot id: A0A1H1KQ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

52773:I6H42 RS03250
gene id: 52773:I6H42_RS03250
uniprot id: A0A1H1KQU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

52773:I6H42 RS07805
gene id: 52773:I6H42_RS07805
uniprot id: A0A1H1Q284
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

52773:I6H42 RS02955
gene id: 52773:I6H42_RS02955
uniprot id: A0A1H1KS37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS02235
gene id: 52773:I6H42_RS02235
uniprot id: A0A1H1M3S4
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS08160
gene id: 52773:I6H42_RS08160
uniprot id: A0A1H1PSS3
names: Similarity
messages: Belongs to the AAA ATPase family.

52773:I6H42 RS02215
gene id: 52773:I6H42_RS02215
uniprot id: A0A1H1M2Y7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

52773:I6H42 RS04350
gene id: 52773:I6H42_RS04350
uniprot id: A0A1H1KQX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

52773:I6H42 RS06105
gene id: 52773:I6H42_RS06105
uniprot id: A0A1H1MQG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

52773:I6H42 RS07770
gene id: 52773:I6H42_RS07770
uniprot id: A0A1H1Q3G9
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS06285
gene id: 52773:I6H42_RS06285
uniprot id: A0A1H1MV08
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

52773:I6H42 RS03590
gene id: 52773:I6H42_RS03590
uniprot id: A0A1H1KQY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

52773:I6H42 RS00345
gene id: 52773:I6H42_RS00345
uniprot id: A0A1H1LUN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

52773:I6H42 RS06045
gene id: 52773:I6H42_RS06045
uniprot id: A0A1H1MRL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

52773:I6H42 RS08520
gene id: 52773:I6H42_RS08520
uniprot id: A0A1H1LHD5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

52773:I6H42 RS04570
gene id: 52773:I6H42_RS04570
uniprot id: A0A1H1KQG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

52773:I6H42 RS08175
gene id: 52773:I6H42_RS08175
uniprot id: A0A1H1PSS0
names: Similarity
messages: Belongs to the peptidase S33 family.

52773:I6H42 RS04060
gene id: 52773:I6H42_RS04060
uniprot id: A0A1H1KRB8
names: Similarity
messages: Belongs to the sulfatase family.

52773:I6H42 RS04085
gene id: 52773:I6H42_RS04085
uniprot id: A0A1H1KS30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

52773:I6H42 RS02730
gene id: 52773:I6H42_RS02730
uniprot id: A0A1H1KSD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

52773:I6H42 RS02280
gene id: 52773:I6H42_RS02280
uniprot id: A0A1H1M2V6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

52773:I6H42 RS05810
gene id: 52773:I6H42_RS05810
uniprot id: A0A1H1MI13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

52773:I6H42 RS07425
gene id: 52773:I6H42_RS07425
uniprot id: A0A1H1KRQ6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

52773:I6H42 RS00430
gene id: 52773:I6H42_RS00430
uniprot id: A0A1H1LVM1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

52773:I6H42 RS03675
gene id: 52773:I6H42_RS03675
uniprot id: A0A1H1KRJ2
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

52773:I6H42 RS00425
gene id: 52773:I6H42_RS00425
uniprot id: A0A1H1LX58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

52773:I6H42 RS03225
gene id: 52773:I6H42_RS03225
uniprot id: A0A1H1KR56
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

52773:I6H42 RS07480
gene id: 52773:I6H42_RS07480
uniprot id: A0A1H1KQU9
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS08090
gene id: 52773:I6H42_RS08090
uniprot id: A0A1H1PUV2
names: Similarity
messages: Belongs to the UPF0749 family.

52773:I6H42 RS01485
gene id: 52773:I6H42_RS01485
uniprot id: A0A1H1L2Z3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

52773:I6H42 RS06880
gene id: 52773:I6H42_RS06880
uniprot id: A0A1H1N8S3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52773:I6H42 RS03065
gene id: 52773:I6H42_RS03065
uniprot id: A0A1H1KSY3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

52773:I6H42 RS08230
gene id: 52773:I6H42_RS08230
uniprot id: A0A1H1PRS6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

52773:I6H42 RS02630
gene id: 52773:I6H42_RS02630
uniprot id: A0A1H1KSJ7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

52773:I6H42 RS05425
gene id: 52773:I6H42_RS05425
uniprot id: A0A1H1KQU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

52773:I6H42 RS04900
gene id: 52773:I6H42_RS04900
uniprot id: A0A1H1PBP6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

52773:I6H42 RS08865
gene id: 52773:I6H42_RS08865
uniprot id: A0A1H1LKP6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52773:I6H42 RS01335
gene id: 52773:I6H42_RS01335
uniprot id: A0A1H1L460
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

52773:I6H42 RS00200
gene id: 52773:I6H42_RS00200
uniprot id: A0A1H1LT25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

52773:I6H42 RS02670
gene id: 52773:I6H42_RS02670
uniprot id: A0A1H1KRV8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

52773:I6H42 RS06085
gene id: 52773:I6H42_RS06085
uniprot id: A0A1H1MPS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

52773:I6H42 RS07800
gene id: 52773:I6H42_RS07800
uniprot id: A0A1H1Q2C7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

52773:I6H42 RS06055
gene id: 52773:I6H42_RS06055
uniprot id: A0A1H1MQI0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

52773:I6H42 RS00400
gene id: 52773:I6H42_RS00400
uniprot id: A0A1H1LWU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

52773:I6H42 RS06225
gene id: 52773:I6H42_RS06225
uniprot id: A0A1H1MTK2
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS04650
gene id: 52773:I6H42_RS04650
uniprot id: A0A1H1PFA0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

52773:I6H42 RS04645
gene id: 52773:I6H42_RS04645
uniprot id: A0A1H1PG39
names: Similarity
messages: Belongs to the malic enzymes family.

52773:I6H42 RS08415
gene id: 52773:I6H42_RS08415
uniprot id: A0A1H1LBJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

52773:I6H42 RS08395
gene id: 52773:I6H42_RS08395
uniprot id: A0A1H1LBX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52773:I6H42 RS04560
gene id: 52773:I6H42_RS04560
uniprot id: A0A1H1KQE8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

52773:I6H42 RS03450
gene id: 52773:I6H42_RS03450
uniprot id: A0A1H1KQW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

52773:I6H42 RS08220
gene id: 52773:I6H42_RS08220
uniprot id: A0A1H1PS74
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

52773:I6H42 RS04655
gene id: 52773:I6H42_RS04655
uniprot id: A0A1H1PF51
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

52773:I6H42 RS03370
gene id: 52773:I6H42_RS03370
uniprot id: A0A1H1KQT4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

52773:I6H42 RS06090
gene id: 52773:I6H42_RS06090
uniprot id: A0A1H1MSL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

52773:I6H42 RS05200
gene id: 52773:I6H42_RS05200
uniprot id: A0A1H1P2E9
names: Similarity
messages: Belongs to the glutamine synthetase family.

52773:I6H42 RS05420
gene id: 52773:I6H42_RS05420
uniprot id: A0A1H1KPY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS06050
gene id: 52773:I6H42_RS06050
uniprot id: A0A1H1MPA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

52773:I6H42 RS02105
gene id: 52773:I6H42_RS02105
uniprot id: A0A1H1KQY4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

52773:I6H42 RS07455
gene id: 52773:I6H42_RS07455
uniprot id: A0A1H1KRH9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

52773:I6H42 RS05785
gene id: 52773:I6H42_RS05785
uniprot id: A0A1H1MI04
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

52773:I6H42 RS02095
gene id: 52773:I6H42_RS02095
uniprot id: A0A1H1KR26
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS04300
gene id: 52773:I6H42_RS04300
uniprot id: A0A1H1KQI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

52773:I6H42 RS01840
gene id: 52773:I6H42_RS01840
uniprot id: A0A1H1KZQ3
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.

52773:I6H42 RS03085
gene id: 52773:I6H42_RS03085
uniprot id: A0A1H1KRX2
names: Similarity
messages: Belongs to the UPF0098 family.

52773:I6H42 RS06520
gene id: 52773:I6H42_RS06520
uniprot id: A0A1H1N0H9
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

52773:I6H42 RS08360
gene id: 52773:I6H42_RS08360
uniprot id: A0A1H1PMM4
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS04555
gene id: 52773:I6H42_RS04555
uniprot id: A0A1H1KQA7
names: Similarity
messages: Belongs to the ribF family.

52773:I6H42 RS07915
gene id: 52773:I6H42_RS07915
uniprot id: A0A1H1PYW2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52773:I6H42 RS06030
gene id: 52773:I6H42_RS06030
uniprot id: A0A1H1MR52
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

52773:I6H42 RS03710
gene id: 52773:I6H42_RS03710
uniprot id: A0A1H1KQR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

52773:I6H42 RS05675
gene id: 52773:I6H42_RS05675
uniprot id: A0A1H1MF13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

52773:I6H42 RS03360
gene id: 52773:I6H42_RS03360
uniprot id: A0A1H1KRQ9
names: Similarity
messages: Belongs to the peptidase M1 family.

52773:I6H42 RS03080
gene id: 52773:I6H42_RS03080
uniprot id: A0A1H1KR99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

52773:I6H42 RS07580
gene id: 52773:I6H42_RS07580
uniprot id: A0A1H1Q7V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

52773:I6H42 RS05065
gene id: 52773:I6H42_RS05065
uniprot id: A0A1H1P5W2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

52773:I6H42 RS05230
gene id: 52773:I6H42_RS05230
uniprot id: A0A1H1P3H6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

52773:I6H42 RS02915
gene id: 52773:I6H42_RS02915
uniprot id: A0A1H1KSY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS05960
gene id: 52773:I6H42_RS05960
uniprot id: A0A1H1MLW5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

52773:I6H42 RS08790
gene id: 52773:I6H42_RS08790
uniprot id: A0A1H1LJR3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

52773:I6H42 RS06000
gene id: 52773:I6H42_RS06000
uniprot id: A0A1H1MQD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

52773:I6H42 RS01880
gene id: 52773:I6H42_RS01880
uniprot id: A0A1H1KYN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS06205
gene id: 52773:I6H42_RS06205
uniprot id: A0A1H1MSR8
names: Similarity
messages: Belongs to the universal stress protein A family.

52773:I6H42 RS04255
gene id: 52773:I6H42_RS04255
uniprot id: A0A1H1KQF8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

52773:I6H42 RS08255
gene id: 52773:I6H42_RS08255
uniprot id: A0A1H1PQY0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

52773:I6H42 RS05925
gene id: 52773:I6H42_RS05925
uniprot id: A0A1H1ML71
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

52773:I6H42 RS01620
gene id: 52773:I6H42_RS01620
uniprot id: A0A1H1L238
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

52773:I6H42 RS06040
gene id: 52773:I6H42_RS06040
uniprot id: A0A1H1MNP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

52773:I6H42 RS04305
gene id: 52773:I6H42_RS04305
uniprot id: A0A1H1KQE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

52773:I6H42 RS05325
gene id: 52773:I6H42_RS05325
uniprot id: A0A1H1NZD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

52773:I6H42 RS04045
gene id: 52773:I6H42_RS04045
uniprot id: A0A1H1KQJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

52773:I6H42 RS02440
gene id: 52773:I6H42_RS02440
uniprot id: A0A1H1KST9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

52773:I6H42 RS04995
gene id: 52773:I6H42_RS04995
uniprot id: A0A1H1P7G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

52773:I6H42 RS03430
gene id: 52773:I6H42_RS03430
uniprot id: A0A1H1KRG8
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

52773:I6H42 RS05510
gene id: 52773:I6H42_RS05510
uniprot id: A0A1H1MD78
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

52773:I6H42 RS00625
gene id: 52773:I6H42_RS00625
uniprot id: A0A1H1KUE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

52773:I6H42 RS01555
gene id: 52773:I6H42_RS01555
uniprot id: A0A1H1L1V3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

52773:I6H42 RS05400
gene id: 52773:I6H42_RS05400
uniprot id: A0A1H1KQQ2
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

52773:I6H42 RS05175
gene id: 52773:I6H42_RS05175
uniprot id: A0A1H1P3H4
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

52773:I6H42 RS02470
gene id: 52773:I6H42_RS02470
uniprot id: A0A1H1KS53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

52773:I6H42 RS06870
gene id: 52773:I6H42_RS06870
uniprot id: A0A1H1N8D8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

52773:I6H42 RS05880
gene id: 52773:I6H42_RS05880
uniprot id: A0A1H1ML38
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

52773:I6H42 RS04670
gene id: 52773:I6H42_RS04670
uniprot id: A0A1H1PF63
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

52773:I6H42 RS04855
gene id: 52773:I6H42_RS04855
uniprot id: A0A1H1PB63
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

52773:I6H42 RS04605
gene id: 52773:I6H42_RS04605
uniprot id: A0A1H1KR15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

52773:I6H42 RS02700
gene id: 52773:I6H42_RS02700
uniprot id: A0A1H1KTF6
names: Similarity
messages: Belongs to the UPF0102 family.

52773:I6H42 RS03350
gene id: 52773:I6H42_RS03350
uniprot id: A0A1H1KRP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

52773:I6H42 RS06185
gene id: 52773:I6H42_RS06185
uniprot id: A0A1H1MSM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

52773:I6H42 RS06170
gene id: 52773:I6H42_RS06170
uniprot id: A0A1H1MS60
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

52773:I6H42 RS03470
gene id: 52773:I6H42_RS03470
uniprot id: A0A1H1KSL9
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

52773:I6H42 RS00250
gene id: 52773:I6H42_RS00250
uniprot id: A0A1H1LT04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

52773:I6H42 RS05895
gene id: 52773:I6H42_RS05895
uniprot id: A0A1H1MK12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

52773:I6H42 RS04195
gene id: 52773:I6H42_RS04195
uniprot id: A0A1H1KS09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

52773:I6H42 RS02740
gene id: 52773:I6H42_RS02740
uniprot id: A0A1H1KRF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

52773:I6H42 RS04150
gene id: 52773:I6H42_RS04150
uniprot id: A0A1H1KQM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

52773:I6H42 RS04565
gene id: 52773:I6H42_RS04565
uniprot id: A0A1H1KRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

52773:I6H42 RS00280
gene id: 52773:I6H42_RS00280
uniprot id: A0A1H1LTK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

52773:I6H42 RS05330
gene id: 52773:I6H42_RS05330
uniprot id: A0A1H1NZD6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

52773:I6H42 RS05975
gene id: 52773:I6H42_RS05975
uniprot id: A0A1H1MMK0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

52773:I6H42 RS07780
gene id: 52773:I6H42_RS07780
uniprot id: A0A1H1Q2Y0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

52773:I6H42 RS06260
gene id: 52773:I6H42_RS06260
uniprot id: A0A1H1MUB5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

52773:I6H42 RS02910
gene id: 52773:I6H42_RS02910
uniprot id: A0A1H1KT54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

52773:I6H42 RS05340
gene id: 52773:I6H42_RS05340
uniprot id: A0A1H1NZ12
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

52773:I6H42 RS00380
gene id: 52773:I6H42_RS00380
uniprot id: A0A1H1LWH8
names: Similarity
messages: Belongs to the DapA family.

52773:I6H42 RS01540
gene id: 52773:I6H42_RS01540
uniprot id: A0A1H1L271
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

52773:I6H42 RS08695
gene id: 52773:I6H42_RS08695
uniprot id: A0A1H1LI72
names: Subcellular Location Annotation
messages: Membrane

52773:I6H42 RS01490
gene id: 52773:I6H42_RS01490
uniprot id: A0A1H1L4K8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

52773:I6H42 RS08720
gene id: 52773:I6H42_RS08720
uniprot id: A0A1H1LIK4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

52773:I6H42 RS00090
gene id: 52773:I6H42_RS00090
uniprot id: A0A1H1LP23
names: Similarity
messages: Belongs to the peptidase S8 family.

52773:I6H42 RS00685
gene id: 52773:I6H42_RS00685
uniprot id: A0A1H1KWC1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

52773:I6H42 RS04310
gene id: 52773:I6H42_RS04310
uniprot id: A0A1H1KR47
names: Similarity
messages: Belongs to the YggT family.

52773:I6H42 RS02050
gene id: 52773:I6H42_RS02050
uniprot id: A0A1H1KQ81
names: Similarity
messages: Belongs to the carbamate kinase family.

52773:I6H42 RS01660
gene id: 52773:I6H42_RS01660
uniprot id: A0A1H1L1A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane