526226:GBRO RS13325
gene id: 526226:GBRO_RS13325
uniprot id: D0L814
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS19840
gene id: 526226:GBRO_RS19840
uniprot id: D0L410
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526226:GBRO RS17175
gene id: 526226:GBRO_RS17175
uniprot id: D0LE54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

526226:GBRO RS01955
gene id: 526226:GBRO_RS01955
uniprot id: D0LDB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526226:GBRO RS16010
gene id: 526226:GBRO_RS16010
uniprot id: D0LC36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526226:GBRO RS14645
gene id: 526226:GBRO_RS14645
uniprot id: D0L9Z1
names: Similarity
messages: Belongs to the TrpC family.

526226:GBRO RS15525
gene id: 526226:GBRO_RS15525
uniprot id: D0LBU3
names: Similarity
messages: Belongs to the AccD/PCCB family.

526226:GBRO RS15070
gene id: 526226:GBRO_RS15070
uniprot id: D0LAU7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

526226:GBRO RS10295
gene id: 526226:GBRO_RS10295
uniprot id: D0LAL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS21950
gene id: 526226:GBRO_RS21950
uniprot id: D0L6J9
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

526226:GBRO RS20155
gene id: 526226:GBRO_RS20155
uniprot id: D0L4K0
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS05285
gene id: 526226:GBRO_RS05285
uniprot id: D0L4F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

526226:GBRO RS10235
gene id: 526226:GBRO_RS10235
uniprot id: D0LAK5
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

526226:GBRO RS08700
gene id: 526226:GBRO_RS08700
uniprot id: D0L8K9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

526226:GBRO RS06815
gene id: 526226:GBRO_RS06815
uniprot id: D0L6B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

526226:GBRO RS09255
gene id: 526226:GBRO_RS09255
uniprot id: D0L9E6
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS20375
gene id: 526226:GBRO_RS20375
uniprot id: D0L4P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

526226:GBRO RS17960
gene id: 526226:GBRO_RS17960
uniprot id: D0LFA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

526226:GBRO RS08150
gene id: 526226:GBRO_RS08150
uniprot id: D0L7R5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

526226:GBRO RS14780
gene id: 526226:GBRO_RS14780
uniprot id: D0LA18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS08415
gene id: 526226:GBRO_RS08415
uniprot id: D0L7V9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS03215
gene id: 526226:GBRO_RS03215
uniprot id: D0L292
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS11425
gene id: 526226:GBRO_RS11425
uniprot id: D0LCM1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

526226:GBRO RS20630
gene id: 526226:GBRO_RS20630
uniprot id: D0L556
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

526226:GBRO RS14235
gene id: 526226:GBRO_RS14235
uniprot id: D0L9R2
names: Similarity
messages: Belongs to the universal stress protein A family.

526226:GBRO RS14770
gene id: 526226:GBRO_RS14770
uniprot id: D0LA16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS06140
gene id: 526226:GBRO_RS06140
uniprot id: D0L5L3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS21600
gene id: 526226:GBRO_RS21600
uniprot id: D0L604
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

526226:GBRO RS01405
gene id: 526226:GBRO_RS01405
uniprot id: D0LCA8
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS22285
gene id: 526226:GBRO_RS22285
uniprot id: D0L6R2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

526226:GBRO RS08765
gene id: 526226:GBRO_RS08765
uniprot id: D0L8M1
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

526226:GBRO RS14450
gene id: 526226:GBRO_RS14450
uniprot id: D0L9V2
names: Similarity
messages: Belongs to the thymidine kinase family.

526226:GBRO RS10215
gene id: 526226:GBRO_RS10215
uniprot id: D0LAK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

526226:GBRO RS02810
gene id: 526226:GBRO_RS02810
uniprot id: D0LEI4
names: Subcellular Location Annotation
messages: Cytoplasm

526226:GBRO RS08640
gene id: 526226:GBRO_RS08640
uniprot id: D0L8J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS20620
gene id: 526226:GBRO_RS20620
uniprot id: D0L554
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS05005
gene id: 526226:GBRO_RS05005
uniprot id: D0L4A2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

526226:GBRO RS01910
gene id: 526226:GBRO_RS01910
uniprot id: D0LDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

526226:GBRO RS16065
gene id: 526226:GBRO_RS16065
uniprot id: D0LC47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

526226:GBRO RS02095
gene id: 526226:GBRO_RS02095
uniprot id: D0LDE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

526226:GBRO RS24075
gene id: 526226:GBRO_RS24075
uniprot id: D0L9C5
names: Similarity
messages: Belongs to the ParB family.

526226:GBRO RS02020
gene id: 526226:GBRO_RS02020
uniprot id: D0LDC6
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS00825
gene id: 526226:GBRO_RS00825
uniprot id: D0LB88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

526226:GBRO RS15190
gene id: 526226:GBRO_RS15190
uniprot id: D0LAX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

526226:GBRO RS16720
gene id: 526226:GBRO_RS16720
uniprot id: D0LD70
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS11440
gene id: 526226:GBRO_RS11440
uniprot id: D0LCM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

526226:GBRO RS11980
gene id: 526226:GBRO_RS11980
uniprot id: D0LDM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS17725
gene id: 526226:GBRO_RS17725
uniprot id: D0LF58
names: Similarity
messages: Belongs to the citrate synthase family.

526226:GBRO RS22870
gene id: 526226:GBRO_RS22870
uniprot id: D0L7E8
names: Similarity
messages: Belongs to the peptidase C56 family.

526226:GBRO RS01935
gene id: 526226:GBRO_RS01935
uniprot id: D0LDA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

526226:GBRO RS10270
gene id: 526226:GBRO_RS10270
uniprot id: D0LAL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

526226:GBRO RS04600
gene id: 526226:GBRO_RS04600
uniprot id: D0L3P5
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

526226:GBRO RS08265
gene id: 526226:GBRO_RS08265
uniprot id: D0L7T7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

526226:GBRO RS19020
gene id: 526226:GBRO_RS19020
uniprot id: D0L375
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS17525
gene id: 526226:GBRO_RS17525
uniprot id: D0LF19
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

526226:GBRO RS12880
gene id: 526226:GBRO_RS12880
uniprot id: D0LEV2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

526226:GBRO RS21535
gene id: 526226:GBRO_RS21535
uniprot id: D0L5Z2
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

526226:GBRO RS00755
gene id: 526226:GBRO_RS00755
uniprot id: D0LB72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

526226:GBRO RS07860
gene id: 526226:GBRO_RS07860
uniprot id: D0L7L1
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS18260
gene id: 526226:GBRO_RS18260
uniprot id: D0L2F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

526226:GBRO RS01120
gene id: 526226:GBRO_RS01120
uniprot id: D0LBE6
names: Similarity
messages: Belongs to the cytochrome P450 family.

526226:GBRO RS10075
gene id: 526226:GBRO_RS10075
uniprot id: D0LAH5
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS11760
gene id: 526226:GBRO_RS11760
uniprot id: D0LCT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

526226:GBRO RS03390
gene id: 526226:GBRO_RS03390
uniprot id: D0L2N6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS03455
gene id: 526226:GBRO_RS03455
uniprot id: D0L2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

526226:GBRO RS18845
gene id: 526226:GBRO_RS18845
uniprot id: D0L341
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS07460
gene id: 526226:GBRO_RS07460
uniprot id: D0L713
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS22565
gene id: 526226:GBRO_RS22565
uniprot id: D0L790
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

526226:GBRO RS01760
gene id: 526226:GBRO_RS01760
uniprot id: D0L5D9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

526226:GBRO RS18645
gene id: 526226:GBRO_RS18645
uniprot id: D0L2N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

526226:GBRO RS15740
gene id: 526226:GBRO_RS15740
uniprot id: D0LBY4
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

526226:GBRO RS05070
gene id: 526226:GBRO_RS05070
uniprot id: D0L4B6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS02445
gene id: 526226:GBRO_RS02445
uniprot id: D0LEA7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

526226:GBRO RS00110
gene id: 526226:GBRO_RS00110
uniprot id: D0LA50
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

526226:GBRO RS17205
gene id: 526226:GBRO_RS17205
uniprot id: D0LE60
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

526226:GBRO RS14400
gene id: 526226:GBRO_RS14400
uniprot id: D0L9U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

526226:GBRO RS01490
gene id: 526226:GBRO_RS01490
uniprot id: D0LCC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

526226:GBRO RS11375
gene id: 526226:GBRO_RS11375
uniprot id: D0LCL1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS02890
gene id: 526226:GBRO_RS02890
uniprot id: D0LEJ8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

526226:GBRO RS10170
gene id: 526226:GBRO_RS10170
uniprot id: D0LAJ2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

526226:GBRO RS03225
gene id: 526226:GBRO_RS03225
uniprot id: D0L294
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

526226:GBRO RS14955
gene id: 526226:GBRO_RS14955
uniprot id: D0LAS5
names: Similarity
messages: Belongs to the YggT family.

526226:GBRO RS09355
gene id: 526226:GBRO_RS09355
uniprot id: D0L9G6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

526226:GBRO RS14190
gene id: 526226:GBRO_RS14190
uniprot id: D0L977
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS10050
gene id: 526226:GBRO_RS10050
uniprot id: D0LAH0
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

526226:GBRO RS21060
gene id: 526226:GBRO_RS21060
uniprot id: D0L5C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

526226:GBRO RS17615
gene id: 526226:GBRO_RS17615
uniprot id: D0LF36
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS13480
gene id: 526226:GBRO_RS13480
uniprot id: D0L842
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

526226:GBRO RS16080
gene id: 526226:GBRO_RS16080
uniprot id: D0LC50
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS11360
gene id: 526226:GBRO_RS11360
uniprot id: D0LCK8
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

526226:GBRO RS21885
gene id: 526226:GBRO_RS21885
uniprot id: D0L660
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS05625
gene id: 526226:GBRO_RS05625
uniprot id: D0L4Z5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

526226:GBRO RS02165
gene id: 526226:GBRO_RS02165
uniprot id: D0LDF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

526226:GBRO RS08465
gene id: 526226:GBRO_RS08465
uniprot id: D0L7W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

526226:GBRO RS12035
gene id: 526226:GBRO_RS12035
uniprot id: D0LDN9
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

526226:GBRO RS14125
gene id: 526226:GBRO_RS14125
uniprot id: D0L965
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

526226:GBRO RS17805
gene id: 526226:GBRO_RS17805
uniprot id: D0LF73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

526226:GBRO RS03130
gene id: 526226:GBRO_RS03130
uniprot id: D0L276
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

526226:GBRO RS14655
gene id: 526226:GBRO_RS14655
uniprot id: D0L9Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

526226:GBRO RS11685
gene id: 526226:GBRO_RS11685
uniprot id: D0LCS1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

526226:GBRO RS19000
gene id: 526226:GBRO_RS19000
uniprot id: D0L371
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526226:GBRO RS19480
gene id: 526226:GBRO_RS19480
uniprot id: D0L3U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

526226:GBRO RS08740
gene id: 526226:GBRO_RS08740
uniprot id: D0L8L6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

526226:GBRO RS07310
gene id: 526226:GBRO_RS07310
uniprot id: D0L6Y6
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

526226:GBRO RS22640
gene id: 526226:GBRO_RS22640
uniprot id: D0L7A6
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

526226:GBRO RS01915
gene id: 526226:GBRO_RS01915
uniprot id: D0LDA5
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS08755
gene id: 526226:GBRO_RS08755
uniprot id: D0L8L9
names: Similarity
messages: Belongs to the cytochrome b560 family.

526226:GBRO RS04625
gene id: 526226:GBRO_RS04625
uniprot id: D0L3Q0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

526226:GBRO RS07660
gene id: 526226:GBRO_RS07660
uniprot id: D0L752
names: Similarity
messages: Belongs to the sulfatase family.

526226:GBRO RS06640
gene id: 526226:GBRO_RS06640
uniprot id: D0L677
names: Similarity
messages: Belongs to the Nudix hydrolase family.

526226:GBRO RS06905
gene id: 526226:GBRO_RS06905
uniprot id: D0L6D0
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS05490
gene id: 526226:GBRO_RS05490
uniprot id: D0L4W8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

526226:GBRO RS16060
gene id: 526226:GBRO_RS16060
uniprot id: D0LC46
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS24105
gene id: 526226:GBRO_RS24105
uniprot id: D0L9D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

526226:GBRO RS07790
gene id: 526226:GBRO_RS07790
uniprot id: D0L777
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526226:GBRO RS15685
gene id: 526226:GBRO_RS15685
uniprot id: D0LBX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

526226:GBRO RS11725
gene id: 526226:GBRO_RS11725
uniprot id: D0LCS9
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

526226:GBRO RS10905
gene id: 526226:GBRO_RS10905
uniprot id: D0LBN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

526226:GBRO RS18395
gene id: 526226:GBRO_RS18395
uniprot id: D0L2I0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

526226:GBRO RS14740
gene id: 526226:GBRO_RS14740
uniprot id: D0LA10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

526226:GBRO RS08275
gene id: 526226:GBRO_RS08275
uniprot id: D0L7T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

526226:GBRO RS17800
gene id: 526226:GBRO_RS17800
uniprot id: D0LF72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

526226:GBRO RS01350
gene id: 526226:GBRO_RS01350
uniprot id: D0LC98
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS18410
gene id: 526226:GBRO_RS18410
uniprot id: D0L2I3
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS08040
gene id: 526226:GBRO_RS08040
uniprot id: D0L7P3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

526226:GBRO RS12510
gene id: 526226:GBRO_RS12510
uniprot id: D0LEN3
names: Similarity
messages: Belongs to the peptidase S1B family.

526226:GBRO RS09165
gene id: 526226:GBRO_RS09165
uniprot id: D0L8V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

526226:GBRO RS00020
gene id: 526226:GBRO_RS00020
uniprot id: D0LA35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

526226:GBRO RS16025
gene id: 526226:GBRO_RS16025
uniprot id: D0LC39
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS10805
gene id: 526226:GBRO_RS10805
uniprot id: D0LBL1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

526226:GBRO RS13855
gene id: 526226:GBRO_RS13855
uniprot id: D0L919
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

526226:GBRO RS14490
gene id: 526226:GBRO_RS14490
uniprot id: D0L9W1
names: Similarity
messages: Belongs to the UPF0225 family.

526226:GBRO RS13000
gene id: 526226:GBRO_RS13000
uniprot id: D0LEX6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

526226:GBRO RS01190
gene id: 526226:GBRO_RS01190
uniprot id: D0LC67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

526226:GBRO RS15700
gene id: 526226:GBRO_RS15700
uniprot id: D0LBX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

526226:GBRO RS14070
gene id: 526226:GBRO_RS14070
uniprot id: D0L954
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS11560
gene id: 526226:GBRO_RS11560
uniprot id: D0LCP8
names: Similarity
messages: Belongs to the peptidase A24 family.

526226:GBRO RS02235
gene id: 526226:GBRO_RS02235
uniprot id: D0LDG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS12215
gene id: 526226:GBRO_RS12215
uniprot id: D0LDS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

526226:GBRO RS21650
gene id: 526226:GBRO_RS21650
uniprot id: D0L613
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

526226:GBRO RS03230
gene id: 526226:GBRO_RS03230
uniprot id: D0L295
names: Similarity
messages: Belongs to the barstar family.

526226:GBRO RS11020
gene id: 526226:GBRO_RS11020
uniprot id: D0LBQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

526226:GBRO RS22600
gene id: 526226:GBRO_RS22600
uniprot id: D0L797
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526226:GBRO RS22965
gene id: 526226:GBRO_RS22965
uniprot id: D0L7G5
names: Similarity
messages: Belongs to the CinA family.

526226:GBRO RS09160
gene id: 526226:GBRO_RS09160
uniprot id: D0L8U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

526226:GBRO RS21410
gene id: 526226:GBRO_RS21410
uniprot id: D0L5W7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526226:GBRO RS12580
gene id: 526226:GBRO_RS12580
uniprot id: D0LEP7
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS18270
gene id: 526226:GBRO_RS18270
uniprot id: D0L2F6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

526226:GBRO RS01965
gene id: 526226:GBRO_RS01965
uniprot id: D0LDB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526226:GBRO RS02310
gene id: 526226:GBRO_RS02310
uniprot id: D0LDI3
names: Similarity
messages: Belongs to the Dps family.

526226:GBRO RS19370
gene id: 526226:GBRO_RS19370
uniprot id: D0L3S0
names: Similarity
messages: Belongs to the cytochrome P450 family.

526226:GBRO RS18915
gene id: 526226:GBRO_RS18915
uniprot id: D0L354
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

526226:GBRO RS18355
gene id: 526226:GBRO_RS18355
uniprot id: D0L2H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

526226:GBRO RS09480
gene id: 526226:GBRO_RS09480
uniprot id: D0L9J0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

526226:GBRO RS16375
gene id: 526226:GBRO_RS16375
uniprot id: D0LD01
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

526226:GBRO RS04855
gene id: 526226:GBRO_RS04855
uniprot id: D0L471
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS05145
gene id: 526226:GBRO_RS05145
uniprot id: D0L4D0
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

526226:GBRO RS14090
gene id: 526226:GBRO_RS14090
uniprot id: D0L958
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS11605
gene id: 526226:GBRO_RS11605
uniprot id: D0LCQ6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

526226:GBRO RS18140
gene id: 526226:GBRO_RS18140
uniprot id: D0L2D1
names: Similarity
messages: Belongs to the mycobacterial PPE family.

526226:GBRO RS02170
gene id: 526226:GBRO_RS02170
uniprot id: D0LDF6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

526226:GBRO RS15675
gene id: 526226:GBRO_RS15675
uniprot id: D0LBX1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

526226:GBRO RS04490
gene id: 526226:GBRO_RS04490
uniprot id: D0L3M3
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

526226:GBRO RS03685
gene id: 526226:GBRO_RS03685
uniprot id: D0L2T8
names: Similarity
messages: Belongs to the peptidase C59 family.

526226:GBRO RS15720
gene id: 526226:GBRO_RS15720
uniprot id: D0LBY0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

526226:GBRO RS21070
gene id: 526226:GBRO_RS21070
uniprot id: D0L5D1
names: Similarity
messages: Belongs to the CsoR family.

526226:GBRO RS05225
gene id: 526226:GBRO_RS05225
uniprot id: D0L4E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

526226:GBRO RS11785
gene id: 526226:GBRO_RS11785
uniprot id: D0LCU1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

526226:GBRO RS17640
gene id: 526226:GBRO_RS17640
uniprot id: D0LF41
names: Similarity
messages: Belongs to the AHA1 family.

526226:GBRO RS00985
gene id: 526226:GBRO_RS00985
uniprot id: D0LBC0
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

526226:GBRO RS03430
gene id: 526226:GBRO_RS03430
uniprot id: D0L2P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

526226:GBRO RS08985
gene id: 526226:GBRO_RS08985
uniprot id: D0L8R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

526226:GBRO RS14485
gene id: 526226:GBRO_RS14485
uniprot id: D0L9W0
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS10430
gene id: 526226:GBRO_RS10430
uniprot id: D0LAP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

526226:GBRO RS05530
gene id: 526226:GBRO_RS05530
uniprot id: D0L4X6
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS19945
gene id: 526226:GBRO_RS19945
uniprot id: D0L431
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

526226:GBRO RS16965
gene id: 526226:GBRO_RS16965
uniprot id: D0LE14
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

526226:GBRO RS11600
gene id: 526226:GBRO_RS11600
uniprot id: D0LCQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

526226:GBRO RS10735
gene id: 526226:GBRO_RS10735
uniprot id: D0LBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

526226:GBRO RS11535
gene id: 526226:GBRO_RS11535
uniprot id: D0LCP3
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

526226:GBRO RS07180
gene id: 526226:GBRO_RS07180
uniprot id: D0L6I8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

526226:GBRO RS09605
gene id: 526226:GBRO_RS09605
uniprot id: D0L9L2
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

526226:GBRO RS15360
gene id: 526226:GBRO_RS15360
uniprot id: D0LB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

526226:GBRO RS13690
gene id: 526226:GBRO_RS13690
uniprot id: D0L8Y7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

526226:GBRO RS14880
gene id: 526226:GBRO_RS14880
uniprot id: D0LAR0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

526226:GBRO RS15455
gene id: 526226:GBRO_RS15455
uniprot id: D0LB23
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS12480
gene id: 526226:GBRO_RS12480
uniprot id: D0LDX8
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

526226:GBRO RS03220
gene id: 526226:GBRO_RS03220
uniprot id: D0L293
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS01265
gene id: 526226:GBRO_RS01265
uniprot id: D0LC82
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

526226:GBRO RS09440
gene id: 526226:GBRO_RS09440
uniprot id: D0L9I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

526226:GBRO RS05495
gene id: 526226:GBRO_RS05495
uniprot id: D0L4W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

526226:GBRO RS19900
gene id: 526226:GBRO_RS19900
uniprot id: D0L422
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS16095
gene id: 526226:GBRO_RS16095
uniprot id: D0LC53
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

526226:GBRO RS12470
gene id: 526226:GBRO_RS12470
uniprot id: D0LDX6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS16725
gene id: 526226:GBRO_RS16725
uniprot id: D0LD71
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526226:GBRO RS19655
gene id: 526226:GBRO_RS19655
uniprot id: D0L3X6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS06810
gene id: 526226:GBRO_RS06810
uniprot id: D0L6B2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

526226:GBRO RS19855
gene id: 526226:GBRO_RS19855
uniprot id: D0L413
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS19645
gene id: 526226:GBRO_RS19645
uniprot id: D0L3X4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS18630
gene id: 526226:GBRO_RS18630
uniprot id: D0L2M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

526226:GBRO RS12405
gene id: 526226:GBRO_RS12405
uniprot id: D0LDW3
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

526226:GBRO RS23715
gene id: 526226:GBRO_RS23715
uniprot id: D0L8F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

526226:GBRO RS01310
gene id: 526226:GBRO_RS01310
uniprot id: D0LC90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS16190
gene id: 526226:GBRO_RS16190
uniprot id: D0LCW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS22840
gene id: 526226:GBRO_RS22840
uniprot id: D0L7E2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

526226:GBRO RS05280
gene id: 526226:GBRO_RS05280
uniprot id: D0L4F7
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS13715
gene id: 526226:GBRO_RS13715
uniprot id: D0L8Z2
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS04155
gene id: 526226:GBRO_RS04155
uniprot id: D0L3F5
names: Similarity
messages: Belongs to the peptidase S9A family.

526226:GBRO RS20110
gene id: 526226:GBRO_RS20110
uniprot id: D0L4J1
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

526226:GBRO RS20325
gene id: 526226:GBRO_RS20325
uniprot id: D0L4N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

526226:GBRO RS16935
gene id: 526226:GBRO_RS16935
uniprot id: D0LE09
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

526226:GBRO RS09655
gene id: 526226:GBRO_RS09655
uniprot id: D0L9M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

526226:GBRO RS11405
gene id: 526226:GBRO_RS11405
uniprot id: D0LCL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

526226:GBRO RS05385
gene id: 526226:GBRO_RS05385
uniprot id: D0L4V0
names: Similarity
messages: Belongs to the peptidase S51 family.

526226:GBRO RS00695
gene id: 526226:GBRO_RS00695
uniprot id: D0LB60
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS23160
gene id: 526226:GBRO_RS23160
uniprot id: D0L7K5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

526226:GBRO RS16220
gene id: 526226:GBRO_RS16220
uniprot id: D0LCX2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

526226:GBRO RS22020
gene id: 526226:GBRO_RS22020
uniprot id: D0L6K8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

526226:GBRO RS18215
gene id: 526226:GBRO_RS18215
uniprot id: D0L2E5
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

526226:GBRO RS22785
gene id: 526226:GBRO_RS22785
uniprot id: D0L7D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS10945
gene id: 526226:GBRO_RS10945
uniprot id: D0LBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS08290
gene id: 526226:GBRO_RS08290
uniprot id: D0L7U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

526226:GBRO RS18650
gene id: 526226:GBRO_RS18650
uniprot id: D0L2N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

526226:GBRO RS01470
gene id: 526226:GBRO_RS01470
uniprot id: D0LCC0
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

526226:GBRO RS06515
gene id: 526226:GBRO_RS06515
uniprot id: D0L5T1
names: Similarity
messages: Belongs to the FPG family.

526226:GBRO RS22490
gene id: 526226:GBRO_RS22490
uniprot id: D0L6V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

526226:GBRO RS12505
gene id: 526226:GBRO_RS12505
uniprot id: D0LEN2
names: Similarity
messages: Belongs to the peptidase S8 family.

526226:GBRO RS20890
gene id: 526226:GBRO_RS20890
uniprot id: D0L5A1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS14035
gene id: 526226:GBRO_RS14035
uniprot id: D0L950
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS14150
gene id: 526226:GBRO_RS14150
uniprot id: D0L970
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

526226:GBRO RS17190
gene id: 526226:GBRO_RS17190
uniprot id: D0LE57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

526226:GBRO RS03020
gene id: 526226:GBRO_RS03020
uniprot id: D0LEM4
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS17130
gene id: 526226:GBRO_RS17130
uniprot id: D0LE45
names: Similarity
messages: Belongs to the phosphohexose mutase family.

526226:GBRO RS13770
gene id: 526226:GBRO_RS13770
uniprot id: D0L903
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

526226:GBRO RS10470
gene id: 526226:GBRO_RS10470
uniprot id: D0LAP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

526226:GBRO RS09445
gene id: 526226:GBRO_RS09445
uniprot id: D0L9I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

526226:GBRO RS13925
gene id: 526226:GBRO_RS13925
uniprot id: D0L931
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS13805
gene id: 526226:GBRO_RS13805
uniprot id: D0L910
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

526226:GBRO RS20360
gene id: 526226:GBRO_RS20360
uniprot id: D0L4P0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526226:GBRO RS11460
gene id: 526226:GBRO_RS11460
uniprot id: D0LCM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

526226:GBRO RS22875
gene id: 526226:GBRO_RS22875
uniprot id: D0L7E9
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS11155
gene id: 526226:GBRO_RS11155
uniprot id: D0LBT1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

526226:GBRO RS04450
gene id: 526226:GBRO_RS04450
uniprot id: D0L3L5
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS13140
gene id: 526226:GBRO_RS13140
uniprot id: D0L7Y4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

526226:GBRO RS11635
gene id: 526226:GBRO_RS11635
uniprot id: D0LCR2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS08545
gene id: 526226:GBRO_RS08545
uniprot id: D0L8I1
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS13810
gene id: 526226:GBRO_RS13810
uniprot id: D0L911
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

526226:GBRO RS09965
gene id: 526226:GBRO_RS09965
uniprot id: D0LAF5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

526226:GBRO RS24095
gene id: 526226:GBRO_RS24095
uniprot id: D0L9C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

526226:GBRO RS02555
gene id: 526226:GBRO_RS02555
uniprot id: D0LED0
names: Similarity
messages: Belongs to the GSP E family.

526226:GBRO RS11495
gene id: 526226:GBRO_RS11495
uniprot id: D0LCN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS09300
gene id: 526226:GBRO_RS09300
uniprot id: D0L9F5
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS04575
gene id: 526226:GBRO_RS04575
uniprot id: D0L3P0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS19385
gene id: 526226:GBRO_RS19385
uniprot id: D0L3S3
names: Similarity
messages: Belongs to the HIBADH-related family.

526226:GBRO RS07435
gene id: 526226:GBRO_RS07435
uniprot id: D0L708
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

526226:GBRO RS05375
gene id: 526226:GBRO_RS05375
uniprot id: D0L4U8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

526226:GBRO RS04775
gene id: 526226:GBRO_RS04775
uniprot id: D0L455
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

526226:GBRO RS02275
gene id: 526226:GBRO_RS02275
uniprot id: D0LDH6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS10645
gene id: 526226:GBRO_RS10645
uniprot id: D0LBI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS06675
gene id: 526226:GBRO_RS06675
uniprot id: D0L684
names: Similarity
messages: Belongs to the AccD/PCCB family.

526226:GBRO RS13575
gene id: 526226:GBRO_RS13575
uniprot id: D0L8W4
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

526226:GBRO RS18450
gene id: 526226:GBRO_RS18450
uniprot id: D0L2J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

526226:GBRO RS19030
gene id: 526226:GBRO_RS19030
uniprot id: D0L377
names: Similarity
messages: Belongs to the AccD/PCCB family.

526226:GBRO RS10480
gene id: 526226:GBRO_RS10480
uniprot id: D0LAQ0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

526226:GBRO RS14170
gene id: 526226:GBRO_RS14170
uniprot id: D0L973
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

526226:GBRO RS01930
gene id: 526226:GBRO_RS01930
uniprot id: D0LDA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526226:GBRO RS19690
gene id: 526226:GBRO_RS19690
uniprot id: D0L3Y3
names: Similarity
messages: Belongs to the cytochrome P450 family.

526226:GBRO RS02530
gene id: 526226:GBRO_RS02530
uniprot id: D0LEC5
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS13390
gene id: 526226:GBRO_RS13390
uniprot id: D0L827
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

526226:GBRO RS14705
gene id: 526226:GBRO_RS14705
uniprot id: D0LA03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

526226:GBRO RS06170
gene id: 526226:GBRO_RS06170
uniprot id: D0L5L9
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

526226:GBRO RS20500
gene id: 526226:GBRO_RS20500
uniprot id: D0L4R4
names: Function
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.

526226:GBRO RS14690
gene id: 526226:GBRO_RS14690
uniprot id: D0LA00
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

526226:GBRO RS07810
gene id: 526226:GBRO_RS07810
uniprot id: D0L779
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

526226:GBRO RS08780
gene id: 526226:GBRO_RS08780
uniprot id: D0L8M4
names: Similarity
messages: Belongs to the peptidase C40 family.

526226:GBRO RS04580
gene id: 526226:GBRO_RS04580
uniprot id: D0L3P1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS04230
gene id: 526226:GBRO_RS04230
uniprot id: D0L3G9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526226:GBRO RS24835
gene id: 526226:GBRO_RS24835
uniprot id: D0L4I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

526226:GBRO RS14115
gene id: 526226:GBRO_RS14115
uniprot id: D0L963
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

526226:GBRO RS21230
gene id: 526226:GBRO_RS21230
uniprot id: D0L5G0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

526226:GBRO RS13985
gene id: 526226:GBRO_RS13985
uniprot id: D0L940
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

526226:GBRO RS19490
gene id: 526226:GBRO_RS19490
uniprot id: D0L3U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

526226:GBRO RS18780
gene id: 526226:GBRO_RS18780
uniprot id: D0L327
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

526226:GBRO RS11385
gene id: 526226:GBRO_RS11385
uniprot id: D0LCL3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

526226:GBRO RS10730
gene id: 526226:GBRO_RS10730
uniprot id: D0LBJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

526226:GBRO RS15015
gene id: 526226:GBRO_RS15015
uniprot id: D0LAT6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS16135
gene id: 526226:GBRO_RS16135
uniprot id: D0LCV5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

526226:GBRO RS17955
gene id: 526226:GBRO_RS17955
uniprot id: D0LFA2
names: Similarity
messages: Belongs to the TPP enzyme family.

526226:GBRO RS22355
gene id: 526226:GBRO_RS22355
uniprot id: D0L6S7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526226:GBRO RS21220
gene id: 526226:GBRO_RS21220
uniprot id: D0L5F8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

526226:GBRO RS02140
gene id: 526226:GBRO_RS02140
uniprot id: D0LDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

526226:GBRO RS14665
gene id: 526226:GBRO_RS14665
uniprot id: D0L9Z5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS03885
gene id: 526226:GBRO_RS03885
uniprot id: D0L2X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

526226:GBRO RS04725
gene id: 526226:GBRO_RS04725
uniprot id: D0L445
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526226:GBRO RS22040
gene id: 526226:GBRO_RS22040
uniprot id: D0L6L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

526226:GBRO RS20560
gene id: 526226:GBRO_RS20560
uniprot id: D0L4S7
names: Similarity
messages: Belongs to the AHA1 family.

526226:GBRO RS05690
gene id: 526226:GBRO_RS05690
uniprot id: D0L509
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

526226:GBRO RS08935
gene id: 526226:GBRO_RS08935
uniprot id: D0L8Q6
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

526226:GBRO RS04800
gene id: 526226:GBRO_RS04800
uniprot id: D0L460
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

526226:GBRO RS17330
gene id: 526226:GBRO_RS17330
uniprot id: D0LE84
names: Similarity
messages: Belongs to the Nudix hydrolase family.

526226:GBRO RS12315
gene id: 526226:GBRO_RS12315
uniprot id: D0LDU5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

526226:GBRO RS10355
gene id: 526226:GBRO_RS10355
uniprot id: D0LAM9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

526226:GBRO RS15355
gene id: 526226:GBRO_RS15355
uniprot id: D0LB03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

526226:GBRO RS18115
gene id: 526226:GBRO_RS18115
uniprot id: D0L2C6
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS09110
gene id: 526226:GBRO_RS09110
uniprot id: D0L8T9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

526226:GBRO RS04355
gene id: 526226:GBRO_RS04355
uniprot id: D0L3J6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS23780
gene id: 526226:GBRO_RS23780
uniprot id: D0L8G2
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS18855
gene id: 526226:GBRO_RS18855
uniprot id: D0L343
names: Similarity
messages: Belongs to the cytochrome P450 family.

526226:GBRO RS19905
gene id: 526226:GBRO_RS19905
uniprot id: D0L423
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

526226:GBRO RS23080
gene id: 526226:GBRO_RS23080
uniprot id: D0L7J0
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

526226:GBRO RS14960
gene id: 526226:GBRO_RS14960
uniprot id: D0LAS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

526226:GBRO RS22430
gene id: 526226:GBRO_RS22430
uniprot id: D0L6U2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS11755
gene id: 526226:GBRO_RS11755
uniprot id: D0LCT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

526226:GBRO RS05395
gene id: 526226:GBRO_RS05395
uniprot id: D0L4V2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

526226:GBRO RS09200
gene id: 526226:GBRO_RS09200
uniprot id: D0L9D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526226:GBRO RS21195
gene id: 526226:GBRO_RS21195
uniprot id: D0L5F3
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

526226:GBRO RS20690
gene id: 526226:GBRO_RS20690
uniprot id: D0L568
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS18305
gene id: 526226:GBRO_RS18305
uniprot id: D0L2G3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS01900
gene id: 526226:GBRO_RS01900
uniprot id: D0LDA2
names: Similarity
messages: Belongs to the YciI family.

526226:GBRO RS13520
gene id: 526226:GBRO_RS13520
uniprot id: D0L849
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS05000
gene id: 526226:GBRO_RS05000
uniprot id: D0L4A1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

526226:GBRO RS19495
gene id: 526226:GBRO_RS19495
uniprot id: D0L3U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

526226:GBRO RS19430
gene id: 526226:GBRO_RS19430
uniprot id: D0L3T2
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

526226:GBRO RS04365
gene id: 526226:GBRO_RS04365
uniprot id: D0L3J8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS15280
gene id: 526226:GBRO_RS15280
uniprot id: D0LAY9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

526226:GBRO RS08670
gene id: 526226:GBRO_RS08670
uniprot id: D0L8K3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

526226:GBRO RS16940
gene id: 526226:GBRO_RS16940
uniprot id: D0LE10
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

526226:GBRO RS22245
gene id: 526226:GBRO_RS22245
uniprot id: D0L6Q4
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS03330
gene id: 526226:GBRO_RS03330
uniprot id: D0L2B5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

526226:GBRO RS08120
gene id: 526226:GBRO_RS08120
uniprot id: D0L7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

526226:GBRO RS04395
gene id: 526226:GBRO_RS04395
uniprot id: D0L3K4
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS04705
gene id: 526226:GBRO_RS04705
uniprot id: D0L441
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

526226:GBRO RS15940
gene id: 526226:GBRO_RS15940
uniprot id: D0LC24
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

526226:GBRO RS13830
gene id: 526226:GBRO_RS13830
uniprot id: D0L914
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

526226:GBRO RS04265
gene id: 526226:GBRO_RS04265
uniprot id: D0L3H7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526226:GBRO RS17420
gene id: 526226:GBRO_RS17420
uniprot id: D0LEA1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

526226:GBRO RS03175
gene id: 526226:GBRO_RS03175
uniprot id: D0L284
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

526226:GBRO RS15095
gene id: 526226:GBRO_RS15095
uniprot id: D0LAV2
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

526226:GBRO RS12295
gene id: 526226:GBRO_RS12295
uniprot id: D0LDU1
names: Similarity
messages: Belongs to the peptidase M24B family.

526226:GBRO RS13175
gene id: 526226:GBRO_RS13175
uniprot id: D0L7Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

526226:GBRO RS04795
gene id: 526226:GBRO_RS04795
uniprot id: D0L459
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS02655
gene id: 526226:GBRO_RS02655
uniprot id: D0LEF2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

526226:GBRO RS03170
gene id: 526226:GBRO_RS03170
uniprot id: D0L283
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

526226:GBRO RS09505
gene id: 526226:GBRO_RS09505
uniprot id: D0L9J5
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS21215
gene id: 526226:GBRO_RS21215
uniprot id: D0L5F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

526226:GBRO RS07490
gene id: 526226:GBRO_RS07490
uniprot id: D0L719
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS17240
gene id: 526226:GBRO_RS17240
uniprot id: D0LE67
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

526226:GBRO RS08635
gene id: 526226:GBRO_RS08635
uniprot id: D0L8J5
names: Similarity
messages: Belongs to the UPF0235 family.

526226:GBRO RS08585
gene id: 526226:GBRO_RS08585
uniprot id: D0L778
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

526226:GBRO RS16990
gene id: 526226:GBRO_RS16990
uniprot id: D0LE19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

526226:GBRO RS18690
gene id: 526226:GBRO_RS18690
uniprot id: D0L312
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

526226:GBRO RS04685
gene id: 526226:GBRO_RS04685
uniprot id: D0L436
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

526226:GBRO RS09970
gene id: 526226:GBRO_RS09970
uniprot id: D0LAF6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

526226:GBRO RS08910
gene id: 526226:GBRO_RS08910
uniprot id: D0L8Q2
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS03295
gene id: 526226:GBRO_RS03295
uniprot id: D0L2A8
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS12865
gene id: 526226:GBRO_RS12865
uniprot id: D0LEV0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

526226:GBRO RS06295
gene id: 526226:GBRO_RS06295
uniprot id: D0L5P2
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

526226:GBRO RS09855
gene id: 526226:GBRO_RS09855
uniprot id: D0LAD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

526226:GBRO RS07595
gene id: 526226:GBRO_RS07595
uniprot id: D0L739
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

526226:GBRO RS16885
gene id: 526226:GBRO_RS16885
uniprot id: D0LDZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

526226:GBRO RS09625
gene id: 526226:GBRO_RS09625
uniprot id: D0L9L6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526226:GBRO RS11825
gene id: 526226:GBRO_RS11825
uniprot id: D0LCU9
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS14445
gene id: 526226:GBRO_RS14445
uniprot id: D0L9V1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

526226:GBRO RS10590
gene id: 526226:GBRO_RS10590
uniprot id: D0LBH1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

526226:GBRO RS10025
gene id: 526226:GBRO_RS10025
uniprot id: D0LAG5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

526226:GBRO RS20625
gene id: 526226:GBRO_RS20625
uniprot id: D0L555
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

526226:GBRO RS11145
gene id: 526226:GBRO_RS11145
uniprot id: D0LBS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

526226:GBRO RS02930
gene id: 526226:GBRO_RS02930
uniprot id: D0LEK6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

526226:GBRO RS12940
gene id: 526226:GBRO_RS12940
uniprot id: D0L5C1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

526226:GBRO RS14900
gene id: 526226:GBRO_RS14900
uniprot id: D0LAR4
names: Similarity
messages: Belongs to the asparaginase 1 family.

526226:GBRO RS06225
gene id: 526226:GBRO_RS06225
uniprot id: D0L5M8
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

526226:GBRO RS23465
gene id: 526226:GBRO_RS23465
uniprot id: D0L8A2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

526226:GBRO RS16685
gene id: 526226:GBRO_RS16685
uniprot id: D0LD63
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526226:GBRO RS12040
gene id: 526226:GBRO_RS12040
uniprot id: D0LDP0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

526226:GBRO RS06195
gene id: 526226:GBRO_RS06195
uniprot id: D0L5M4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS18640
gene id: 526226:GBRO_RS18640
uniprot id: D0L2M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

526226:GBRO RS04010
gene id: 526226:GBRO_RS04010
uniprot id: D0L301
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

526226:GBRO RS18835
gene id: 526226:GBRO_RS18835
uniprot id: D0L339
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS20715
gene id: 526226:GBRO_RS20715
uniprot id: D0L572
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

526226:GBRO RS15245
gene id: 526226:GBRO_RS15245
uniprot id: D0LAY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

526226:GBRO RS23580
gene id: 526226:GBRO_RS23580
uniprot id: D0L8C5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

526226:GBRO RS04950
gene id: 526226:GBRO_RS04950
uniprot id: D0L490
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

526226:GBRO RS12995
gene id: 526226:GBRO_RS12995
uniprot id: D0LEX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

526226:GBRO RS18905
gene id: 526226:GBRO_RS18905
uniprot id: D0L352
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

526226:GBRO RS23725
gene id: 526226:GBRO_RS23725
uniprot id: D0L8F3
names: Subcellular Location Annotation
messages: Cytoplasm

526226:GBRO RS12660
gene id: 526226:GBRO_RS12660
uniprot id: D0LER2
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

526226:GBRO RS02265
gene id: 526226:GBRO_RS02265
uniprot id: D0LDH4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

526226:GBRO RS20640
gene id: 526226:GBRO_RS20640
uniprot id: D0L558
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS05420
gene id: 526226:GBRO_RS05420
uniprot id: D0L4V8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

526226:GBRO RS23100
gene id: 526226:GBRO_RS23100
uniprot id: D0L7J3
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

526226:GBRO RS17225
gene id: 526226:GBRO_RS17225
uniprot id: D0LE64
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS09710
gene id: 526226:GBRO_RS09710
uniprot id: D0L9N3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

526226:GBRO RS22880
gene id: 526226:GBRO_RS22880
uniprot id: D0L7F0
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS02405
gene id: 526226:GBRO_RS02405
uniprot id: D0LDJ8
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

526226:GBRO RS18570
gene id: 526226:GBRO_RS18570
uniprot id: D0L2L7
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS11715
gene id: 526226:GBRO_RS11715
uniprot id: D0LCS7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

526226:GBRO RS06630
gene id: 526226:GBRO_RS06630
uniprot id: D0L675
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS18345
gene id: 526226:GBRO_RS18345
uniprot id: D0L2H0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

526226:GBRO RS06450
gene id: 526226:GBRO_RS06450
uniprot id: D0L5S1
names: Similarity
messages: Belongs to the glutamine synthetase family.

526226:GBRO RS09715
gene id: 526226:GBRO_RS09715
uniprot id: D0L9N4
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS10225
gene id: 526226:GBRO_RS10225
uniprot id: D0LAK3
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

526226:GBRO RS06500
gene id: 526226:GBRO_RS06500
uniprot id: D0L5S8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS08300
gene id: 526226:GBRO_RS08300
uniprot id: D0L7U4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

526226:GBRO RS07510
gene id: 526226:GBRO_RS07510
uniprot id: D0L723
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS15775
gene id: 526226:GBRO_RS15775
uniprot id: D0LBZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

526226:GBRO RS14265
gene id: 526226:GBRO_RS14265
uniprot id: D0L9R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

526226:GBRO RS03915
gene id: 526226:GBRO_RS03915
uniprot id: D0L2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS05095
gene id: 526226:GBRO_RS05095
uniprot id: D0L4C0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS20310
gene id: 526226:GBRO_RS20310
uniprot id: D0L4M9
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS03755
gene id: 526226:GBRO_RS03755
uniprot id: D0L2V2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

526226:GBRO RS01735
gene id: 526226:GBRO_RS01735
uniprot id: D0LCG6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

526226:GBRO RS15450
gene id: 526226:GBRO_RS15450
uniprot id: D0LB21
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS04605
gene id: 526226:GBRO_RS04605
uniprot id: D0L3P6
names: Function
names: Similarity
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.

526226:GBRO RS23835
gene id: 526226:GBRO_RS23835
uniprot id: D0L8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS08235
gene id: 526226:GBRO_RS08235
uniprot id: D0L7T1
names: Similarity
messages: Belongs to the FBPase class 2 family.

526226:GBRO RS22395
gene id: 526226:GBRO_RS22395
uniprot id: D0L6T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS01155
gene id: 526226:GBRO_RS01155
uniprot id: D0LBF3
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

526226:GBRO RS19245
gene id: 526226:GBRO_RS19245
uniprot id: D0L3B8
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.
messages: Belongs to the FMO family.

526226:GBRO RS10675
gene id: 526226:GBRO_RS10675
uniprot id: D0LBI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

526226:GBRO RS09495
gene id: 526226:GBRO_RS09495
uniprot id: D0L9J3
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS15215
gene id: 526226:GBRO_RS15215
uniprot id: D0LAX6
names: Similarity
messages: Belongs to the asparagine synthetase family.

526226:GBRO RS17765
gene id: 526226:GBRO_RS17765
uniprot id: D0LF66
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS07525
gene id: 526226:GBRO_RS07525
uniprot id: D0L726
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

526226:GBRO RS18750
gene id: 526226:GBRO_RS18750
uniprot id: D0L321
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

526226:GBRO RS08630
gene id: 526226:GBRO_RS08630
uniprot id: D0L8J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

526226:GBRO RS09735
gene id: 526226:GBRO_RS09735
uniprot id: D0L9N8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

526226:GBRO RS12270
gene id: 526226:GBRO_RS12270
uniprot id: D0LDT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

526226:GBRO RS19475
gene id: 526226:GBRO_RS19475
uniprot id: D0L3U3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

526226:GBRO RS02820
gene id: 526226:GBRO_RS02820
uniprot id: D0LEI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

526226:GBRO RS03985
gene id: 526226:GBRO_RS03985
uniprot id: D0L2Z6
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

526226:GBRO RS04235
gene id: 526226:GBRO_RS04235
uniprot id: D0L3H0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526226:GBRO RS15745
gene id: 526226:GBRO_RS15745
uniprot id: D0LBY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

526226:GBRO RS07870
gene id: 526226:GBRO_RS07870
uniprot id: D0L7L3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS10460
gene id: 526226:GBRO_RS10460
uniprot id: D0LAP6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS06115
gene id: 526226:GBRO_RS06115
uniprot id: D0L5K9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS07250
gene id: 526226:GBRO_RS07250
uniprot id: D0L6X4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS04475
gene id: 526226:GBRO_RS04475
uniprot id: D0L3M0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS01250
gene id: 526226:GBRO_RS01250
uniprot id: D0LC79
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

526226:GBRO RS21940
gene id: 526226:GBRO_RS21940
uniprot id: D0L6J7
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS01960
gene id: 526226:GBRO_RS01960
uniprot id: D0LDB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526226:GBRO RS09450
gene id: 526226:GBRO_RS09450
uniprot id: D0L9I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: In the C-terminal section; belongs to the ATPase delta chain family.
messages: In the N-terminal section; belongs to the ATPase B chain family.
messages: Membrane
messages: This fusion protein includes a component of the F(0) channel (subunit b) and of the F(1) subunit (subunit delta). Two copies of subunit b and one of delta together form the peripheral 'stator' stalk which links F(1) to F(0).
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

526226:GBRO RS14635
gene id: 526226:GBRO_RS14635
uniprot id: D0L9Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

526226:GBRO RS19910
gene id: 526226:GBRO_RS19910
uniprot id: D0L424
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

526226:GBRO RS19100
gene id: 526226:GBRO_RS19100
uniprot id: D0L391
names: Similarity
messages: Belongs to the cytochrome P450 family.

526226:GBRO RS16700
gene id: 526226:GBRO_RS16700
uniprot id: D0LD66
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

526226:GBRO RS11690
gene id: 526226:GBRO_RS11690
uniprot id: D0LCS2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

526226:GBRO RS01840
gene id: 526226:GBRO_RS01840
uniprot id: D0LD90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

526226:GBRO RS11610
gene id: 526226:GBRO_RS11610
uniprot id: D0LCQ7
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

526226:GBRO RS13465
gene id: 526226:GBRO_RS13465
uniprot id: D0L839
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS08140
gene id: 526226:GBRO_RS08140
uniprot id: D0L7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

526226:GBRO RS11865
gene id: 526226:GBRO_RS11865
uniprot id: D0LDK5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

526226:GBRO RS03290
gene id: 526226:GBRO_RS03290
uniprot id: D0L2A7
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS08165
gene id: 526226:GBRO_RS08165
uniprot id: D0L7R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

526226:GBRO RS12125
gene id: 526226:GBRO_RS12125
uniprot id: D0LDQ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

526226:GBRO RS04220
gene id: 526226:GBRO_RS04220
uniprot id: D0L3G7
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS11285
gene id: 526226:GBRO_RS11285
uniprot id: D0LCK0
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

526226:GBRO RS06740
gene id: 526226:GBRO_RS06740
uniprot id: D0L698
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526226:GBRO RS13650
gene id: 526226:GBRO_RS13650
uniprot id: D0L8X9
names: Similarity
messages: Belongs to the UreD family.

526226:GBRO RS16330
gene id: 526226:GBRO_RS16330
uniprot id: D0LCZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

526226:GBRO RS06370
gene id: 526226:GBRO_RS06370
uniprot id: D0L5Q8
names: Cofactor
messages: Binds 1 FAD per subunit.

526226:GBRO RS21870
gene id: 526226:GBRO_RS21870
uniprot id: D0L657
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS22575
gene id: 526226:GBRO_RS22575
uniprot id: D0L792
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS16310
gene id: 526226:GBRO_RS16310
uniprot id: D0LCY8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

526226:GBRO RS01905
gene id: 526226:GBRO_RS01905
uniprot id: D0LDA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526226:GBRO RS15515
gene id: 526226:GBRO_RS15515
uniprot id: D0LBU1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

526226:GBRO RS19880
gene id: 526226:GBRO_RS19880
uniprot id: D0L418
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS04150
gene id: 526226:GBRO_RS04150
uniprot id: D0L3F4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

526226:GBRO RS00750
gene id: 526226:GBRO_RS00750
uniprot id: D0LB71
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS19435
gene id: 526226:GBRO_RS19435
uniprot id: D0L3T3
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

526226:GBRO RS16045
gene id: 526226:GBRO_RS16045
uniprot id: D0LC43
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

526226:GBRO RS10100
gene id: 526226:GBRO_RS10100
uniprot id: D0LAI0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

526226:GBRO RS23875
gene id: 526226:GBRO_RS23875
uniprot id: D0L984
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS11475
gene id: 526226:GBRO_RS11475
uniprot id: D0LCN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS00885
gene id: 526226:GBRO_RS00885
uniprot id: D0LBA0
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

526226:GBRO RS18220
gene id: 526226:GBRO_RS18220
uniprot id: D0L2E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS02435
gene id: 526226:GBRO_RS02435
uniprot id: D0LEA5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

526226:GBRO RS23020
gene id: 526226:GBRO_RS23020
uniprot id: D0L7H7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

526226:GBRO RS06915
gene id: 526226:GBRO_RS06915
uniprot id: D0L6D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

526226:GBRO RS12325
gene id: 526226:GBRO_RS12325
uniprot id: D0LDU7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

526226:GBRO RS22650
gene id: 526226:GBRO_RS22650
uniprot id: D0L7A8
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS10250
gene id: 526226:GBRO_RS10250
uniprot id: D0LAK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

526226:GBRO RS14930
gene id: 526226:GBRO_RS14930
uniprot id: D0LAS0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

526226:GBRO RS16070
gene id: 526226:GBRO_RS16070
uniprot id: D0LC48
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

526226:GBRO RS20425
gene id: 526226:GBRO_RS20425
uniprot id: D0L4Q0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

526226:GBRO RS15910
gene id: 526226:GBRO_RS15910
uniprot id: D0LC18
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

526226:GBRO RS10015
gene id: 526226:GBRO_RS10015
uniprot id: D0LAG3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

526226:GBRO RS16920
gene id: 526226:GBRO_RS16920
uniprot id: D0LE06
names: Similarity
messages: Belongs to the fructosamine kinase family.

526226:GBRO RS19845
gene id: 526226:GBRO_RS19845
uniprot id: D0L411
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526226:GBRO RS15725
gene id: 526226:GBRO_RS15725
uniprot id: D0LBY1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

526226:GBRO RS14355
gene id: 526226:GBRO_RS14355
uniprot id: D0L9T6
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS03030
gene id: 526226:GBRO_RS03030
uniprot id: D0LEM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526226:GBRO RS09485
gene id: 526226:GBRO_RS09485
uniprot id: D0L9J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS08045
gene id: 526226:GBRO_RS08045
uniprot id: D0L7P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

526226:GBRO RS15975
gene id: 526226:GBRO_RS15975
uniprot id: D0LC31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial histone-like protein family. Long actinobacterial subfamily.
messages: nucleoid

526226:GBRO RS14985
gene id: 526226:GBRO_RS14985
uniprot id: D0LAT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

526226:GBRO RS09320
gene id: 526226:GBRO_RS09320
uniprot id: D0L5D9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

526226:GBRO RS06070
gene id: 526226:GBRO_RS06070
uniprot id: D0L5K0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

526226:GBRO RS11860
gene id: 526226:GBRO_RS11860
uniprot id: D0LDK4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

526226:GBRO RS20130
gene id: 526226:GBRO_RS20130
uniprot id: D0L4J5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

526226:GBRO RS23210
gene id: 526226:GBRO_RS23210
uniprot id: D0L856
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS07225
gene id: 526226:GBRO_RS07225
uniprot id: D0L6W9
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

526226:GBRO RS21810
gene id: 526226:GBRO_RS21810
uniprot id: D0L645
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS01175
gene id: 526226:GBRO_RS01175
uniprot id: D0LC64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS11430
gene id: 526226:GBRO_RS11430
uniprot id: D0LCM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

526226:GBRO RS18455
gene id: 526226:GBRO_RS18455
uniprot id: D0L2J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

526226:GBRO RS02060
gene id: 526226:GBRO_RS02060
uniprot id: D0LDD5
names: Similarity
messages: Belongs to the peptidase S1 family.

526226:GBRO RS14560
gene id: 526226:GBRO_RS14560
uniprot id: D0L9X4
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS11950
gene id: 526226:GBRO_RS11950
uniprot id: D0LDM2
names: Similarity
messages: Belongs to the peptidase C40 family.

526226:GBRO RS00945
gene id: 526226:GBRO_RS00945
uniprot id: D0LBB2
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

526226:GBRO RS11745
gene id: 526226:GBRO_RS11745
uniprot id: D0LCT3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

526226:GBRO RS22980
gene id: 526226:GBRO_RS22980
uniprot id: D0L7G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS18035
gene id: 526226:GBRO_RS18035
uniprot id: D0LFB7
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

526226:GBRO RS22455
gene id: 526226:GBRO_RS22455
uniprot id: D0L6U7
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS09380
gene id: 526226:GBRO_RS09380
uniprot id: D0L9H1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS09840
gene id: 526226:GBRO_RS09840
uniprot id: D0LAD2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-73 and Arg-76) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

526226:GBRO RS10070
gene id: 526226:GBRO_RS10070
uniprot id: D0LAH4
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS14240
gene id: 526226:GBRO_RS14240
uniprot id: D0L9R3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

526226:GBRO RS15795
gene id: 526226:GBRO_RS15795
uniprot id: D0LBZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

526226:GBRO RS20990
gene id: 526226:GBRO_RS20990
uniprot id: D0L5B8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS14555
gene id: 526226:GBRO_RS14555
uniprot id: D0L9X3
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS23830
gene id: 526226:GBRO_RS23830
uniprot id: D0L8H2
names: Similarity
messages: Belongs to the glutamine synthetase family.

526226:GBRO RS02545
gene id: 526226:GBRO_RS02545
uniprot id: D0LEC8
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS08690
gene id: 526226:GBRO_RS08690
uniprot id: D0L8K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

526226:GBRO RS10855
gene id: 526226:GBRO_RS10855
uniprot id: D0LBM1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS19735
gene id: 526226:GBRO_RS19735
uniprot id: D0L3Z2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526226:GBRO RS10680
gene id: 526226:GBRO_RS10680
uniprot id: D0LBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

526226:GBRO RS07555
gene id: 526226:GBRO_RS07555
uniprot id: D0L732
names: Similarity
messages: Belongs to the ArsC family.

526226:GBRO RS18680
gene id: 526226:GBRO_RS18680
uniprot id: D0L310
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

526226:GBRO RS07175
gene id: 526226:GBRO_RS07175
uniprot id: D0L6I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

526226:GBRO RS09940
gene id: 526226:GBRO_RS09940
uniprot id: D0LAF1
names: Similarity
messages: Belongs to the YciI family.

526226:GBRO RS04875
gene id: 526226:GBRO_RS04875
uniprot id: D0L475
names: Similarity
messages: Belongs to the cytochrome P450 family.

526226:GBRO RS12330
gene id: 526226:GBRO_RS12330
uniprot id: D0LDU8
names: Similarity
messages: Belongs to the CobH/CbiC family.

526226:GBRO RS13975
gene id: 526226:GBRO_RS13975
uniprot id: D0L938
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

526226:GBRO RS10145
gene id: 526226:GBRO_RS10145
uniprot id: D0LAI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

526226:GBRO RS11095
gene id: 526226:GBRO_RS11095
uniprot id: D0LBS0
names: Similarity
messages: Belongs to the histone deacetylase family.

526226:GBRO RS09745
gene id: 526226:GBRO_RS09745
uniprot id: D0L9P0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

526226:GBRO RS16290
gene id: 526226:GBRO_RS16290
uniprot id: D0LCY4
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

526226:GBRO RS08885
gene id: 526226:GBRO_RS08885
uniprot id: D0L8P7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS17170
gene id: 526226:GBRO_RS17170
uniprot id: D0LE53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

526226:GBRO RS16280
gene id: 526226:GBRO_RS16280
uniprot id: D0LCY2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526226:GBRO RS05965
gene id: 526226:GBRO_RS05965
uniprot id: D0L5I2
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

526226:GBRO RS07700
gene id: 526226:GBRO_RS07700
uniprot id: D0L760
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

526226:GBRO RS15415
gene id: 526226:GBRO_RS15415
uniprot id: D0LB15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

526226:GBRO RS07785
gene id: 526226:GBRO_RS07785
uniprot id: D0L776
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

526226:GBRO RS15545
gene id: 526226:GBRO_RS15545
uniprot id: D0LBU7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526226:GBRO RS10105
gene id: 526226:GBRO_RS10105
uniprot id: D0LAI1
names: Similarity
messages: Belongs to the FPG family.

526226:GBRO RS07535
gene id: 526226:GBRO_RS07535
uniprot id: D0L728
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

526226:GBRO RS22645
gene id: 526226:GBRO_RS22645
uniprot id: D0L7A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

526226:GBRO RS23735
gene id: 526226:GBRO_RS23735
uniprot id: D0L8F4
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS11805
gene id: 526226:GBRO_RS11805
uniprot id: D0LCU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

526226:GBRO RS22300
gene id: 526226:GBRO_RS22300
uniprot id: D0L6R5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526226:GBRO RS13675
gene id: 526226:GBRO_RS13675
uniprot id: D0L8Y4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

526226:GBRO RS22235
gene id: 526226:GBRO_RS22235
uniprot id: D0L6Q2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS22025
gene id: 526226:GBRO_RS22025
uniprot id: D0L6K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

526226:GBRO RS17425
gene id: 526226:GBRO_RS17425
uniprot id: D0LEA2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

526226:GBRO RS21260
gene id: 526226:GBRO_RS21260
uniprot id: D0L5G7
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS04020
gene id: 526226:GBRO_RS04020
uniprot id: D0L303
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

526226:GBRO RS12365
gene id: 526226:GBRO_RS12365
uniprot id: D0LDV5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS21840
gene id: 526226:GBRO_RS21840
uniprot id: D0L651
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

526226:GBRO RS14730
gene id: 526226:GBRO_RS14730
uniprot id: D0LA08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

526226:GBRO RS00150
gene id: 526226:GBRO_RS00150
uniprot id: D0LA58
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS02045
gene id: 526226:GBRO_RS02045
uniprot id: D0LDD1
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS20185
gene id: 526226:GBRO_RS20185
uniprot id: D0L4K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS13035
gene id: 526226:GBRO_RS13035
uniprot id: D0LEY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

526226:GBRO RS11435
gene id: 526226:GBRO_RS11435
uniprot id: D0LCM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

526226:GBRO RS08495
gene id: 526226:GBRO_RS08495
uniprot id: D0L7X5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

526226:GBRO RS14110
gene id: 526226:GBRO_RS14110
uniprot id: D0L962
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

526226:GBRO RS01180
gene id: 526226:GBRO_RS01180
uniprot id: D0LC65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS02980
gene id: 526226:GBRO_RS02980
uniprot id: D0LEL6
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS09260
gene id: 526226:GBRO_RS09260
uniprot id: D0L9E7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS15270
gene id: 526226:GBRO_RS15270
uniprot id: D0LAY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

526226:GBRO RS17795
gene id: 526226:GBRO_RS17795
uniprot id: D0LF71
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

526226:GBRO RS14965
gene id: 526226:GBRO_RS14965
uniprot id: D0LAS7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

526226:GBRO RS03325
gene id: 526226:GBRO_RS03325
uniprot id: D0L2B4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

526226:GBRO RS10330
gene id: 526226:GBRO_RS10330
uniprot id: D0LAM4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

526226:GBRO RS17920
gene id: 526226:GBRO_RS17920
uniprot id: D0LF95
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS10615
gene id: 526226:GBRO_RS10615
uniprot id: D0LBH6
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

526226:GBRO RS05425
gene id: 526226:GBRO_RS05425
uniprot id: D0L4V9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

526226:GBRO RS00435
gene id: 526226:GBRO_RS00435
uniprot id: D0LAB1
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

526226:GBRO RS09455
gene id: 526226:GBRO_RS09455
uniprot id: D0L9I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

526226:GBRO RS18770
gene id: 526226:GBRO_RS18770
uniprot id: D0L325
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS10230
gene id: 526226:GBRO_RS10230
uniprot id: D0LAK4
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

526226:GBRO RS04185
gene id: 526226:GBRO_RS04185
uniprot id: D0L3G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

526226:GBRO RS13620
gene id: 526226:GBRO_RS13620
uniprot id: D0L8X3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

526226:GBRO RS08745
gene id: 526226:GBRO_RS08745
uniprot id: D0L8L7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

526226:GBRO RS04545
gene id: 526226:GBRO_RS04545
uniprot id: D0L3N4
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

526226:GBRO RS19580
gene id: 526226:GBRO_RS19580
uniprot id: D0L3W2
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

526226:GBRO RS18715
gene id: 526226:GBRO_RS18715
uniprot id: D0L316
names: Similarity
messages: Belongs to the asparagine synthetase family.

526226:GBRO RS05450
gene id: 526226:GBRO_RS05450
uniprot id: D0L4W1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

526226:GBRO RS15835
gene id: 526226:GBRO_RS15835
uniprot id: D0LC03
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

526226:GBRO RS19995
gene id: 526226:GBRO_RS19995
uniprot id: D0L4G9
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS02515
gene id: 526226:GBRO_RS02515
uniprot id: D0LEC2
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS22720
gene id: 526226:GBRO_RS22720
uniprot id: D0L7C2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

526226:GBRO RS20685
gene id: 526226:GBRO_RS20685
uniprot id: D0L567
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526226:GBRO RS13670
gene id: 526226:GBRO_RS13670
uniprot id: D0L8Y3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

526226:GBRO RS19180
gene id: 526226:GBRO_RS19180
uniprot id: D0L3A6
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS15620
gene id: 526226:GBRO_RS15620
uniprot id: D0LBW1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

526226:GBRO RS11445
gene id: 526226:GBRO_RS11445
uniprot id: D0LCM5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

526226:GBRO RS10280
gene id: 526226:GBRO_RS10280
uniprot id: D0LAL4
names: Similarity
messages: Belongs to the acylphosphatase family.

526226:GBRO RS05175
gene id: 526226:GBRO_RS05175
uniprot id: D0L4D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

526226:GBRO RS16745
gene id: 526226:GBRO_RS16745
uniprot id: D0LD75
names: Similarity
messages: Belongs to the cytochrome P450 family.

526226:GBRO RS14640
gene id: 526226:GBRO_RS14640
uniprot id: D0L9Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

526226:GBRO RS11480
gene id: 526226:GBRO_RS11480
uniprot id: D0LCN2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

526226:GBRO RS15570
gene id: 526226:GBRO_RS15570
uniprot id: D0LBV2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS12220
gene id: 526226:GBRO_RS12220
uniprot id: D0LDS6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets.

526226:GBRO RS21120
gene id: 526226:GBRO_RS21120
uniprot id: D0L5D9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

526226:GBRO RS17605
gene id: 526226:GBRO_RS17605
uniprot id: D0LF34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

526226:GBRO RS13235
gene id: 526226:GBRO_RS13235
uniprot id: D0L7Z9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

526226:GBRO RS02210
gene id: 526226:GBRO_RS02210
uniprot id: D0LDG3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS09585
gene id: 526226:GBRO_RS09585
uniprot id: D0L9K8
names: Function
names: Similarity
messages: Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
messages: Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia.

526226:GBRO RS06045
gene id: 526226:GBRO_RS06045
uniprot id: D0L5J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

526226:GBRO RS15930
gene id: 526226:GBRO_RS15930
uniprot id: D0LC22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

526226:GBRO RS18330
gene id: 526226:GBRO_RS18330
uniprot id: D0L2G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

526226:GBRO RS20540
gene id: 526226:GBRO_RS20540
uniprot id: D0L4S3
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS07605
gene id: 526226:GBRO_RS07605
uniprot id: D0L741
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

526226:GBRO RS05480
gene id: 526226:GBRO_RS05480
uniprot id: D0L4W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

526226:GBRO RS22450
gene id: 526226:GBRO_RS22450
uniprot id: D0L6U6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

526226:GBRO RS20180
gene id: 526226:GBRO_RS20180
uniprot id: D0L4K5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

526226:GBRO RS19340
gene id: 526226:GBRO_RS19340
uniprot id: D0L3R4
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS12420
gene id: 526226:GBRO_RS12420
uniprot id: D0LDW6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

526226:GBRO RS11975
gene id: 526226:GBRO_RS11975
uniprot id: D0LDM7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

526226:GBRO RS18360
gene id: 526226:GBRO_RS18360
uniprot id: D0L2H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

526226:GBRO RS18255
gene id: 526226:GBRO_RS18255
uniprot id: D0L2F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

526226:GBRO RS01950
gene id: 526226:GBRO_RS01950
uniprot id: D0LDB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526226:GBRO RS09600
gene id: 526226:GBRO_RS09600
uniprot id: D0L9L1
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

526226:GBRO RS08710
gene id: 526226:GBRO_RS08710
uniprot id: D0L8L1
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS10500
gene id: 526226:GBRO_RS10500
uniprot id: D0LAQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

526226:GBRO RS08895
gene id: 526226:GBRO_RS08895
uniprot id: D0L8P9
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

526226:GBRO RS01445
gene id: 526226:GBRO_RS01445
uniprot id: D0LCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

526226:GBRO RS10890
gene id: 526226:GBRO_RS10890
uniprot id: D0LBM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

526226:GBRO RS10985
gene id: 526226:GBRO_RS10985
uniprot id: D0LBP7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526226:GBRO RS09825
gene id: 526226:GBRO_RS09825
uniprot id: D0L9Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

526226:GBRO RS01395
gene id: 526226:GBRO_RS01395
uniprot id: D0LCA6
names: Similarity
messages: Belongs to the AHA1 family.

526226:GBRO RS15120
gene id: 526226:GBRO_RS15120
uniprot id: D0LAV7
names: Similarity
messages: Belongs to the arsA ATPase family.

526226:GBRO RS12895
gene id: 526226:GBRO_RS12895
uniprot id: D0LEV5
names: Similarity
messages: Belongs to the CsoR family.

526226:GBRO RS18340
gene id: 526226:GBRO_RS18340
uniprot id: D0L2G9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

526226:GBRO RS06755
gene id: 526226:GBRO_RS06755
uniprot id: D0L6A1
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

526226:GBRO RS13725
gene id: 526226:GBRO_RS13725
uniprot id: D0L8Z4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526226:GBRO RS07830
gene id: 526226:GBRO_RS07830
uniprot id: D0L783
names: Similarity
messages: Belongs to the pirin family.

526226:GBRO RS19680
gene id: 526226:GBRO_RS19680
uniprot id: D0L3Y1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526226:GBRO RS10770
gene id: 526226:GBRO_RS10770
uniprot id: D0LBK4
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

526226:GBRO RS13130
gene id: 526226:GBRO_RS13130
uniprot id: D0L7Y2
names: Function
names: Similarity
messages: Belongs to the MerB family.
messages: Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.

526226:GBRO RS17755
gene id: 526226:GBRO_RS17755
uniprot id: D0LF64
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS13580
gene id: 526226:GBRO_RS13580
uniprot id: D0L8W5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

526226:GBRO RS16380
gene id: 526226:GBRO_RS16380
uniprot id: D0LD02
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

526226:GBRO RS19035
gene id: 526226:GBRO_RS19035
uniprot id: D0L378
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS11055
gene id: 526226:GBRO_RS11055
uniprot id: D0LBR2
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

526226:GBRO RS23500
gene id: 526226:GBRO_RS23500
uniprot id: D0L8A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

526226:GBRO RS16105
gene id: 526226:GBRO_RS16105
uniprot id: D0LC55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS08805
gene id: 526226:GBRO_RS08805
uniprot id: D0L8M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

526226:GBRO RS12310
gene id: 526226:GBRO_RS12310
uniprot id: D0LDU4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

526226:GBRO RS08410
gene id: 526226:GBRO_RS08410
uniprot id: D0L7V8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS11850
gene id: 526226:GBRO_RS11850
uniprot id: D0LCV4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

526226:GBRO RS01920
gene id: 526226:GBRO_RS01920
uniprot id: D0LDA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526226:GBRO RS16415
gene id: 526226:GBRO_RS16415
uniprot id: D0LD08
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

526226:GBRO RS11505
gene id: 526226:GBRO_RS11505
uniprot id: D0LCN7
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS20960
gene id: 526226:GBRO_RS20960
uniprot id: D0L5B5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

526226:GBRO RS09465
gene id: 526226:GBRO_RS09465
uniprot id: D0L9I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

526226:GBRO RS11140
gene id: 526226:GBRO_RS11140
uniprot id: D0LBS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS15670
gene id: 526226:GBRO_RS15670
uniprot id: D0LBX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

526226:GBRO RS03965
gene id: 526226:GBRO_RS03965
uniprot id: D0L2Z3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

526226:GBRO RS23960
gene id: 526226:GBRO_RS23960
uniprot id: D0L9A1
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

526226:GBRO RS15750
gene id: 526226:GBRO_RS15750
uniprot id: D0LBY6
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

526226:GBRO RS15965
gene id: 526226:GBRO_RS15965
uniprot id: D0LC29
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

526226:GBRO RS21645
gene id: 526226:GBRO_RS21645
uniprot id: D0L612
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

526226:GBRO RS18445
gene id: 526226:GBRO_RS18445
uniprot id: D0L2J1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

526226:GBRO RS10305
gene id: 526226:GBRO_RS10305
uniprot id: D0LAL9
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

526226:GBRO RS04805
gene id: 526226:GBRO_RS04805
uniprot id: D0L461
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

526226:GBRO RS02510
gene id: 526226:GBRO_RS02510
uniprot id: D0LEC1
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

526226:GBRO RS13120
gene id: 526226:GBRO_RS13120
uniprot id: D0L7Y1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

526226:GBRO RS00540
gene id: 526226:GBRO_RS00540
uniprot id: D0LAD0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526226:GBRO RS06765
gene id: 526226:GBRO_RS06765
uniprot id: D0L6A2
names: Similarity
messages: Belongs to the AHA1 family.

526226:GBRO RS11670
gene id: 526226:GBRO_RS11670
uniprot id: D0LCR8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS22825
gene id: 526226:GBRO_RS22825
uniprot id: D0L7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

526226:GBRO RS07945
gene id: 526226:GBRO_RS07945
uniprot id: D0L7M5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

526226:GBRO RS03280
gene id: 526226:GBRO_RS03280
uniprot id: D0L2A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS11025
gene id: 526226:GBRO_RS11025
uniprot id: D0LBQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

526226:GBRO RS21155
gene id: 526226:GBRO_RS21155
uniprot id: D0L5E5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS05430
gene id: 526226:GBRO_RS05430
uniprot id: D0L4W0
names: Similarity
messages: Belongs to the UPF0234 family.

526226:GBRO RS14230
gene id: 526226:GBRO_RS14230
uniprot id: D0L9R1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

526226:GBRO RS07240
gene id: 526226:GBRO_RS07240
uniprot id: D0L6X2
names: Similarity
messages: Belongs to the universal stress protein A family.

526226:GBRO RS20055
gene id: 526226:GBRO_RS20055
uniprot id: D0L4I0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

526226:GBRO RS10830
gene id: 526226:GBRO_RS10830
uniprot id: D0LBL6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS09460
gene id: 526226:GBRO_RS09460
uniprot id: D0L9I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

526226:GBRO RS05340
gene id: 526226:GBRO_RS05340
uniprot id: D0L4U1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS14615
gene id: 526226:GBRO_RS14615
uniprot id: D0L9Y5
names: Similarity
messages: Belongs to the glutamate synthase family.

526226:GBRO RS12275
gene id: 526226:GBRO_RS12275
uniprot id: D0LDT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

526226:GBRO RS18660
gene id: 526226:GBRO_RS18660
uniprot id: D0L306
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

526226:GBRO RS09405
gene id: 526226:GBRO_RS09405
uniprot id: D0L9H5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

526226:GBRO RS11795
gene id: 526226:GBRO_RS11795
uniprot id: D0LCU3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS10535
gene id: 526226:GBRO_RS10535
uniprot id: D0LBG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

526226:GBRO RS07405
gene id: 526226:GBRO_RS07405
uniprot id: D0L703
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

526226:GBRO RS10285
gene id: 526226:GBRO_RS10285
uniprot id: D0LAL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

526226:GBRO RS05635
gene id: 526226:GBRO_RS05635
uniprot id: D0L4Z7
names: Similarity
messages: Belongs to the peptidase S33 family.

526226:GBRO RS04500
gene id: 526226:GBRO_RS04500
uniprot id: D0L3M5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526226:GBRO RS07440
gene id: 526226:GBRO_RS07440
uniprot id: D0L709
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

526226:GBRO RS03120
gene id: 526226:GBRO_RS03120
uniprot id: D0L274
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

526226:GBRO RS00385
gene id: 526226:GBRO_RS00385
uniprot id: D0LAA1
names: Subcellular Location Annotation
messages: Secreted

526226:GBRO RS09370
gene id: 526226:GBRO_RS09370
uniprot id: D0L9G9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

526226:GBRO RS15715
gene id: 526226:GBRO_RS15715
uniprot id: D0LBX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

526226:GBRO RS02255
gene id: 526226:GBRO_RS02255
uniprot id: D0LDH2
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS16085
gene id: 526226:GBRO_RS16085
uniprot id: D0LC51
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS18250
gene id: 526226:GBRO_RS18250
uniprot id: D0L2F2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

526226:GBRO RS13605
gene id: 526226:GBRO_RS13605
uniprot id: D0L8X0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

526226:GBRO RS08420
gene id: 526226:GBRO_RS08420
uniprot id: D0L7W0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

526226:GBRO RS11575
gene id: 526226:GBRO_RS11575
uniprot id: D0LCQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

526226:GBRO RS17165
gene id: 526226:GBRO_RS17165
uniprot id: D0LE52
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

526226:GBRO RS23790
gene id: 526226:GBRO_RS23790
uniprot id: D0L8G4
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS22685
gene id: 526226:GBRO_RS22685
uniprot id: D0L7B5
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

526226:GBRO RS12200
gene id: 526226:GBRO_RS12200
uniprot id: D0LDS2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

526226:GBRO RS21085
gene id: 526226:GBRO_RS21085
uniprot id: D0L5D4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

526226:GBRO RS07820
gene id: 526226:GBRO_RS07820
uniprot id: D0L781
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS00035
gene id: 526226:GBRO_RS00035
uniprot id: D0LA38
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

526226:GBRO RS10865
gene id: 526226:GBRO_RS10865
uniprot id: D0LBM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

526226:GBRO RS08175
gene id: 526226:GBRO_RS08175
uniprot id: D0L7S0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS21065
gene id: 526226:GBRO_RS21065
uniprot id: D0L5D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

526226:GBRO RS08770
gene id: 526226:GBRO_RS08770
uniprot id: D0L8M2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS12030
gene id: 526226:GBRO_RS12030
uniprot id: D0LDN8
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

526226:GBRO RS06210
gene id: 526226:GBRO_RS06210
uniprot id: D0L5M5
names: Similarity
messages: Belongs to the citrate synthase family.

526226:GBRO RS09365
gene id: 526226:GBRO_RS09365
uniprot id: D0L9G8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

526226:GBRO RS03265
gene id: 526226:GBRO_RS03265
uniprot id: D0L2A2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes.

526226:GBRO RS03680
gene id: 526226:GBRO_RS03680
uniprot id: D0L2T7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

526226:GBRO RS24045
gene id: 526226:GBRO_RS24045
uniprot id: D0L9B9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526226:GBRO RS21010
gene id: 526226:GBRO_RS21010
uniprot id: D0L5C1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

526226:GBRO RS15960
gene id: 526226:GBRO_RS15960
uniprot id: D0LC28
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

526226:GBRO RS10915
gene id: 526226:GBRO_RS10915
uniprot id: D0LBN3
names: Similarity
messages: Belongs to the PspA/IM30 family.

526226:GBRO RS10320
gene id: 526226:GBRO_RS10320
uniprot id: D0LAM2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

526226:GBRO RS00665
gene id: 526226:GBRO_RS00665
uniprot id: D0LB54
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526226:GBRO RS13695
gene id: 526226:GBRO_RS13695
uniprot id: D0L8Y8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

526226:GBRO RS12625
gene id: 526226:GBRO_RS12625
uniprot id: D0LEQ5
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

526226:GBRO RS23505
gene id: 526226:GBRO_RS23505
uniprot id: D0L8B0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS16985
gene id: 526226:GBRO_RS16985
uniprot id: D0LE18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526226:GBRO RS23815
gene id: 526226:GBRO_RS23815
uniprot id: D0L8G9
names: Similarity
messages: Belongs to the glutamate synthase family.

526226:GBRO RS08950
gene id: 526226:GBRO_RS08950
uniprot id: D0L8Q9
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

526226:GBRO RS09635
gene id: 526226:GBRO_RS09635
uniprot id: D0L9L8
names: Similarity
messages: Belongs to the UPF0045 family.

526226:GBRO RS16625
gene id: 526226:GBRO_RS16625
uniprot id: D0LD51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

526226:GBRO RS09400
gene id: 526226:GBRO_RS09400
uniprot id: D0L9H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

526226:GBRO RS07260
gene id: 526226:GBRO_RS07260
uniprot id: D0L6X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

526226:GBRO RS19120
gene id: 526226:GBRO_RS19120
uniprot id: D0L395
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526226:GBRO RS22270
gene id: 526226:GBRO_RS22270
uniprot id: D0L6Q9
names: Similarity
messages: Belongs to the pirin family.

526226:GBRO RS14920
gene id: 526226:GBRO_RS14920
uniprot id: D0LAR8
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

526226:GBRO RS02975
gene id: 526226:GBRO_RS02975
uniprot id: D0LEL5
names: Similarity
messages: Belongs to the peptidase M1 family.

526226:GBRO RS10190
gene id: 526226:GBRO_RS10190
uniprot id: D0LAJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

526226:GBRO RS11730
gene id: 526226:GBRO_RS11730
uniprot id: D0LCT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

526226:GBRO RS11545
gene id: 526226:GBRO_RS11545
uniprot id: D0LCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

526226:GBRO RS16365
gene id: 526226:GBRO_RS16365
uniprot id: D0LCZ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

526226:GBRO RS11695
gene id: 526226:GBRO_RS11695
uniprot id: D0LCS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

526226:GBRO RS11570
gene id: 526226:GBRO_RS11570
uniprot id: D0LCQ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526226:GBRO RS10935
gene id: 526226:GBRO_RS10935
uniprot id: D0LBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

526226:GBRO RS16455
gene id: 526226:GBRO_RS16455
uniprot id: D0LD16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

526226:GBRO RS22215
gene id: 526226:GBRO_RS22215
uniprot id: D0L6P8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

526226:GBRO RS14725
gene id: 526226:GBRO_RS14725
uniprot id: D0LA07
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

526226:GBRO RS17460
gene id: 526226:GBRO_RS17460
uniprot id: D0LF06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

526226:GBRO RS06255
gene id: 526226:GBRO_RS06255
uniprot id: D0L5N4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

526226:GBRO RS06610
gene id: 526226:GBRO_RS06610
uniprot id: D0L672
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

526226:GBRO RS07570
gene id: 526226:GBRO_RS07570
uniprot id: D0L735
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

526226:GBRO RS10525
gene id: 526226:GBRO_RS10525
uniprot id: D0LBF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

526226:GBRO RS08205
gene id: 526226:GBRO_RS08205
uniprot id: D0L7S6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

526226:GBRO RS21265
gene id: 526226:GBRO_RS21265
uniprot id: D0L5G8
names: Similarity
messages: Belongs to the peptidase S8 family.

526226:GBRO RS11630
gene id: 526226:GBRO_RS11630
uniprot id: D0LCR1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

526226:GBRO RS13780
gene id: 526226:GBRO_RS13780
uniprot id: D0L905
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

526226:GBRO RS11510
gene id: 526226:GBRO_RS11510
uniprot id: D0LCN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS20275
gene id: 526226:GBRO_RS20275
uniprot id: D0L4M2
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS19975
gene id: 526226:GBRO_RS19975
uniprot id: D0L4G5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

526226:GBRO RS10425
gene id: 526226:GBRO_RS10425
uniprot id: D0LAP3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

526226:GBRO RS15205
gene id: 526226:GBRO_RS15205
uniprot id: D0LAX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

526226:GBRO RS19390
gene id: 526226:GBRO_RS19390
uniprot id: D0L3S4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS10165
gene id: 526226:GBRO_RS10165
uniprot id: D0LAJ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

526226:GBRO RS20670
gene id: 526226:GBRO_RS20670
uniprot id: D0L564
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

526226:GBRO RS12965
gene id: 526226:GBRO_RS12965
uniprot id: D0LEW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

526226:GBRO RS12145
gene id: 526226:GBRO_RS12145
uniprot id: D0LDR0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

526226:GBRO RS15305
gene id: 526226:GBRO_RS15305
uniprot id: D0LAZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

526226:GBRO RS13710
gene id: 526226:GBRO_RS13710
uniprot id: D0L8Z1
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS23010
gene id: 526226:GBRO_RS23010
uniprot id: D0L7H5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS10290
gene id: 526226:GBRO_RS10290
uniprot id: D0LAL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

526226:GBRO RS18935
gene id: 526226:GBRO_RS18935
uniprot id: D0L358
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

526226:GBRO RS16215
gene id: 526226:GBRO_RS16215
uniprot id: D0LCX1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

526226:GBRO RS00495
gene id: 526226:GBRO_RS00495
uniprot id: D0LAC2
names: Similarity
messages: Belongs to the CFA/CMAS family.

526226:GBRO RS04390
gene id: 526226:GBRO_RS04390
uniprot id: D0L3K3
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS20860
gene id: 526226:GBRO_RS20860
uniprot id: D0L597
names: Similarity
messages: Belongs to the DapA family.

526226:GBRO RS02840
gene id: 526226:GBRO_RS02840
uniprot id: D0LEI9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS19740
gene id: 526226:GBRO_RS19740
uniprot id: D0L3Z3
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

526226:GBRO RS05555
gene id: 526226:GBRO_RS05555
uniprot id: D0L4Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

526226:GBRO RS09900
gene id: 526226:GBRO_RS09900
uniprot id: D0LAE3
names: Similarity
messages: Belongs to the neutral ceramidase family.

526226:GBRO RS18110
gene id: 526226:GBRO_RS18110
uniprot id: D0L2C5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

526226:GBRO RS21050
gene id: 526226:GBRO_RS21050
uniprot id: D0L5C7
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS03765
gene id: 526226:GBRO_RS03765
uniprot id: D0L2V4
names: Cofactor
messages: Can also use Mn(2+) ion.

526226:GBRO RS15640
gene id: 526226:GBRO_RS15640
uniprot id: D0LBW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS13700
gene id: 526226:GBRO_RS13700
uniprot id: D0L8Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

526226:GBRO RS06635
gene id: 526226:GBRO_RS06635
uniprot id: D0L676
names: Similarity
messages: Belongs to the AccD/PCCB family.

526226:GBRO RS22580
gene id: 526226:GBRO_RS22580
uniprot id: D0L793
names: Similarity
messages: Belongs to the CsoR family.

526226:GBRO RS02225
gene id: 526226:GBRO_RS02225
uniprot id: D0LDG6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526226:GBRO RS23510
gene id: 526226:GBRO_RS23510
uniprot id: D0L8B1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

526226:GBRO RS05915
gene id: 526226:GBRO_RS05915
uniprot id: D0L550
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

526226:GBRO RS13875
gene id: 526226:GBRO_RS13875
uniprot id: D0L922
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526226:GBRO RS02935
gene id: 526226:GBRO_RS02935
uniprot id: D0LEK7
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

526226:GBRO RS08825
gene id: 526226:GBRO_RS08825
uniprot id: D0L8N3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

526226:GBRO RS16575
gene id: 526226:GBRO_RS16575
uniprot id: D0LD40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

526226:GBRO RS16730
gene id: 526226:GBRO_RS16730
uniprot id: D0LD72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

526226:GBRO RS18635
gene id: 526226:GBRO_RS18635
uniprot id: D0L2M8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

526226:GBRO RS16495
gene id: 526226:GBRO_RS16495
uniprot id: D0LD25
names: Similarity
messages: Belongs to the LOG family.

526226:GBRO RS17930
gene id: 526226:GBRO_RS17930
uniprot id: D0LF97
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS04755
gene id: 526226:GBRO_RS04755
uniprot id: D0L451
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

526226:GBRO RS05510
gene id: 526226:GBRO_RS05510
uniprot id: D0L4X2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS06175
gene id: 526226:GBRO_RS06175
uniprot id: D0L5M0
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

526226:GBRO RS15400
gene id: 526226:GBRO_RS15400
uniprot id: D0LB12
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

526226:GBRO RS04160
gene id: 526226:GBRO_RS04160
uniprot id: D0L3F6
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS18670
gene id: 526226:GBRO_RS18670
uniprot id: D0L308
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

526226:GBRO RS11540
gene id: 526226:GBRO_RS11540
uniprot id: D0LCP4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

526226:GBRO RS20955
gene id: 526226:GBRO_RS20955
uniprot id: D0L5B4
names: Similarity
messages: Belongs to the universal stress protein A family.

526226:GBRO RS08540
gene id: 526226:GBRO_RS08540
uniprot id: D0L8I0
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS09470
gene id: 526226:GBRO_RS09470
uniprot id: D0L9I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

526226:GBRO RS00785
gene id: 526226:GBRO_RS00785
uniprot id: D0LB80
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

526226:GBRO RS10715
gene id: 526226:GBRO_RS10715
uniprot id: D0LBJ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS10160
gene id: 526226:GBRO_RS10160
uniprot id: D0LAJ0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

526226:GBRO RS12170
gene id: 526226:GBRO_RS12170
uniprot id: D0LDR5
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS19990
gene id: 526226:GBRO_RS19990
uniprot id: D0L4G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

526226:GBRO RS07665
gene id: 526226:GBRO_RS07665
uniprot id: D0L753
names: Function
names: Similarity
messages: Belongs to the Stf0 sulfotransferase family.
messages: Catalyzes the sulfuryl group transfer from 3'-phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S).

526226:GBRO RS02360
gene id: 526226:GBRO_RS02360
uniprot id: D0LDJ1
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS07800
gene id: 526226:GBRO_RS07800
uniprot id: D0L778
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

526226:GBRO RS18490
gene id: 526226:GBRO_RS18490
uniprot id: D0L2K0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526226:GBRO RS12240
gene id: 526226:GBRO_RS12240
uniprot id: D0LDT0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

526226:GBRO RS10080
gene id: 526226:GBRO_RS10080
uniprot id: D0LAH6
names: Subcellular Location Annotation
messages: Cytoplasm

526226:GBRO RS08500
gene id: 526226:GBRO_RS08500
uniprot id: D0L7X6
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

526226:GBRO RS08975
gene id: 526226:GBRO_RS08975
uniprot id: D0L8R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

526226:GBRO RS12960
gene id: 526226:GBRO_RS12960
uniprot id: D0LEW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

526226:GBRO RS20755
gene id: 526226:GBRO_RS20755
uniprot id: D0L580
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS16370
gene id: 526226:GBRO_RS16370
uniprot id: D0LD00
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

526226:GBRO RS18070
gene id: 526226:GBRO_RS18070
uniprot id: D0LFC5
names: Similarity
messages: Belongs to the cytochrome P450 family.

526226:GBRO RS07495
gene id: 526226:GBRO_RS07495
uniprot id: D0L720
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

526226:GBRO RS23495
gene id: 526226:GBRO_RS23495
uniprot id: D0L8A8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

526226:GBRO RS15155
gene id: 526226:GBRO_RS15155
uniprot id: D0LAW4
names: Similarity
messages: Belongs to the peptidase C40 family.

526226:GBRO RS11010
gene id: 526226:GBRO_RS11010
uniprot id: D0LBQ2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

526226:GBRO RS02880
gene id: 526226:GBRO_RS02880
uniprot id: D0LEJ6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

526226:GBRO RS06935
gene id: 526226:GBRO_RS06935
uniprot id: D0L6D8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

526226:GBRO RS10940
gene id: 526226:GBRO_RS10940
uniprot id: D0LBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS09305
gene id: 526226:GBRO_RS09305
uniprot id: D0L9F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

526226:GBRO RS11045
gene id: 526226:GBRO_RS11045
uniprot id: D0LBR0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

526226:GBRO RS17550
gene id: 526226:GBRO_RS17550
uniprot id: D0LF24
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

526226:GBRO RS06335
gene id: 526226:GBRO_RS06335
uniprot id: D0L5Q0
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

526226:GBRO RS14785
gene id: 526226:GBRO_RS14785
uniprot id: D0LA19
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

526226:GBRO RS07675
gene id: 526226:GBRO_RS07675
uniprot id: D0L755
names: Function
names: Similarity
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.

526226:GBRO RS19660
gene id: 526226:GBRO_RS19660
uniprot id: D0L3X7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS15275
gene id: 526226:GBRO_RS15275
uniprot id: D0LAY8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

526226:GBRO RS11640
gene id: 526226:GBRO_RS11640
uniprot id: D0LCR3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

526226:GBRO RS07270
gene id: 526226:GBRO_RS07270
uniprot id: D0L6X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

526226:GBRO RS18665
gene id: 526226:GBRO_RS18665
uniprot id: D0L307
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

526226:GBRO RS08315
gene id: 526226:GBRO_RS08315
uniprot id: D0L7U7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS20470
gene id: 526226:GBRO_RS20470
uniprot id: D0L4Q9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

526226:GBRO RS09730
gene id: 526226:GBRO_RS09730
uniprot id: D0L9N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

526226:GBRO RS09685
gene id: 526226:GBRO_RS09685
uniprot id: D0L9M8
names: Similarity
messages: Belongs to the peptidase S58 family.

526226:GBRO RS15895
gene id: 526226:GBRO_RS15895
uniprot id: D0LC15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

526226:GBRO RS20905
gene id: 526226:GBRO_RS20905
uniprot id: D0L5A4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

526226:GBRO RS09245
gene id: 526226:GBRO_RS09245
uniprot id: D0L9E4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

526226:GBRO RS08720
gene id: 526226:GBRO_RS08720
uniprot id: D0L8L3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

526226:GBRO RS07295
gene id: 526226:GBRO_RS07295
uniprot id: D0L6Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526226:GBRO RS06940
gene id: 526226:GBRO_RS06940
uniprot id: D0L6D9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

526226:GBRO RS10930
gene id: 526226:GBRO_RS10930
uniprot id: D0LBN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

526226:GBRO RS01210
gene id: 526226:GBRO_RS01210
uniprot id: D0LC71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS14340
gene id: 526226:GBRO_RS14340
uniprot id: D0L9T3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

526226:GBRO RS10505
gene id: 526226:GBRO_RS10505
uniprot id: D0LBF4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

526226:GBRO RS17710
gene id: 526226:GBRO_RS17710
uniprot id: D0LF55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

526226:GBRO RS18675
gene id: 526226:GBRO_RS18675
uniprot id: D0L309
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

526226:GBRO RS12645
gene id: 526226:GBRO_RS12645
uniprot id: D0LEQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

526226:GBRO RS01660
gene id: 526226:GBRO_RS01660
uniprot id: D0LCF1
names: Similarity
messages: Belongs to the hyi family.

526226:GBRO RS16345
gene id: 526226:GBRO_RS16345
uniprot id: D0LCZ5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

526226:GBRO RS08665
gene id: 526226:GBRO_RS08665
uniprot id: D0L8K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

526226:GBRO RS14130
gene id: 526226:GBRO_RS14130
uniprot id: D0L966
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

526226:GBRO RS15520
gene id: 526226:GBRO_RS15520
uniprot id: D0LBU2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

526226:GBRO RS02425
gene id: 526226:GBRO_RS02425
uniprot id: D0LDK1
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

526226:GBRO RS17035
gene id: 526226:GBRO_RS17035
uniprot id: D0LE28
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

526226:GBRO RS08515
gene id: 526226:GBRO_RS08515
uniprot id: D0L7X9
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS18520
gene id: 526226:GBRO_RS18520
uniprot id: D0L2K7
names: Similarity
messages: Belongs to the pirin family.

526226:GBRO RS11620
gene id: 526226:GBRO_RS11620
uniprot id: D0LCQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

526226:GBRO RS15875
gene id: 526226:GBRO_RS15875
uniprot id: D0LC11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

526226:GBRO RS14570
gene id: 526226:GBRO_RS14570
uniprot id: D0L9X6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

526226:GBRO RS02925
gene id: 526226:GBRO_RS02925
uniprot id: D0LEK5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

526226:GBRO RS21955
gene id: 526226:GBRO_RS21955
uniprot id: D0L6K0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS00585
gene id: 526226:GBRO_RS00585
uniprot id: D0LB37
names: Similarity
messages: Belongs to the glutamate synthase family.

526226:GBRO RS23485
gene id: 526226:GBRO_RS23485
uniprot id: D0L8A6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

526226:GBRO RS18910
gene id: 526226:GBRO_RS18910
uniprot id: D0L353
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

526226:GBRO RS02480
gene id: 526226:GBRO_RS02480
uniprot id: D0LEB5
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

526226:GBRO RS11065
gene id: 526226:GBRO_RS11065
uniprot id: D0LBR4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS07575
gene id: 526226:GBRO_RS07575
uniprot id: D0L736
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS23980
gene id: 526226:GBRO_RS23980
uniprot id: D0L9A5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

526226:GBRO RS15410
gene id: 526226:GBRO_RS15410
uniprot id: D0LB14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

526226:GBRO RS07955
gene id: 526226:GBRO_RS07955
uniprot id: D0L7M7
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

526226:GBRO RS16600
gene id: 526226:GBRO_RS16600
uniprot id: D0LD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526226:GBRO RS20435
gene id: 526226:GBRO_RS20435
uniprot id: D0L4Q2
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS15980
gene id: 526226:GBRO_RS15980
uniprot id: D0LC32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

526226:GBRO RS09610
gene id: 526226:GBRO_RS09610
uniprot id: D0L9L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

526226:GBRO RS20745
gene id: 526226:GBRO_RS20745
uniprot id: D0L578
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS04750
gene id: 526226:GBRO_RS04750
uniprot id: D0L450
names: Similarity
messages: Belongs to the Nth/MutY family.

526226:GBRO RS10895
gene id: 526226:GBRO_RS10895
uniprot id: D0LBM9
names: Similarity
messages: Belongs to the YciI family.

526226:GBRO RS11320
gene id: 526226:GBRO_RS11320
uniprot id: D0LCK3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS20910
gene id: 526226:GBRO_RS20910
uniprot id: D0L5A5
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS16680
gene id: 526226:GBRO_RS16680
uniprot id: D0LD62
names: Similarity
messages: Belongs to the asp23 family.

526226:GBRO RS04880
gene id: 526226:GBRO_RS04880
uniprot id: D0L476
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

526226:GBRO RS06550
gene id: 526226:GBRO_RS06550
uniprot id: D0L5T8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS16535
gene id: 526226:GBRO_RS16535
uniprot id: D0LD33
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

526226:GBRO RS02015
gene id: 526226:GBRO_RS02015
uniprot id: D0LDC5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS20315
gene id: 526226:GBRO_RS20315
uniprot id: D0L4N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

526226:GBRO RS04995
gene id: 526226:GBRO_RS04995
uniprot id: D0L4A0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

526226:GBRO RS01345
gene id: 526226:GBRO_RS01345
uniprot id: D0LC97
names: Similarity
messages: Belongs to the ABC transporter superfamily.

526226:GBRO RS11090
gene id: 526226:GBRO_RS11090
uniprot id: D0LBR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS10550
gene id: 526226:GBRO_RS10550
uniprot id: D0LBG3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

526226:GBRO RS04905
gene id: 526226:GBRO_RS04905
uniprot id: D0L481
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

526226:GBRO RS22110
gene id: 526226:GBRO_RS22110
uniprot id: D0L6M6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526226:GBRO RS16955
gene id: 526226:GBRO_RS16955
uniprot id: D0LE13
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS08210
gene id: 526226:GBRO_RS08210
uniprot id: D0L7S7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS18245
gene id: 526226:GBRO_RS18245
uniprot id: D0L2F1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

526226:GBRO RS06730
gene id: 526226:GBRO_RS06730
uniprot id: D0L695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS21565
gene id: 526226:GBRO_RS21565
uniprot id: D0L5Z8
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS07650
gene id: 526226:GBRO_RS07650
uniprot id: D0L750
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

526226:GBRO RS09435
gene id: 526226:GBRO_RS09435
uniprot id: D0L9I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

526226:GBRO RS01995
gene id: 526226:GBRO_RS01995
uniprot id: D0LDC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

526226:GBRO RS09420
gene id: 526226:GBRO_RS09420
uniprot id: D0L9H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS10220
gene id: 526226:GBRO_RS10220
uniprot id: D0LAK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

526226:GBRO RS14630
gene id: 526226:GBRO_RS14630
uniprot id: D0L9Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

526226:GBRO RS15985
gene id: 526226:GBRO_RS15985
uniprot id: D0LC33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

526226:GBRO RS12920
gene id: 526226:GBRO_RS12920
uniprot id: D0LEW0
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS02215
gene id: 526226:GBRO_RS02215
uniprot id: D0LDG4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS07910
gene id: 526226:GBRO_RS07910
uniprot id: D0L7L9
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS20650
gene id: 526226:GBRO_RS20650
uniprot id: D0L560
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

526226:GBRO RS08145
gene id: 526226:GBRO_RS08145
uniprot id: D0L7R4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS13400
gene id: 526226:GBRO_RS13400
uniprot id: D0L828
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

526226:GBRO RS24375
gene id: 526226:GBRO_RS24375
uniprot id: D0LFI7
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

526226:GBRO RS07950
gene id: 526226:GBRO_RS07950
uniprot id: D0L7M6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

526226:GBRO RS12530
gene id: 526226:GBRO_RS12530
uniprot id: D0LEN7
names: Similarity
messages: Belongs to the AHA1 family.

526226:GBRO RS22695
gene id: 526226:GBRO_RS22695
uniprot id: D0L7B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

526226:GBRO RS13625
gene id: 526226:GBRO_RS13625
uniprot id: D0L8X4
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

526226:GBRO RS12110
gene id: 526226:GBRO_RS12110
uniprot id: D0LDQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

526226:GBRO RS13080
gene id: 526226:GBRO_RS13080
uniprot id: D0LEZ4
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS24060
gene id: 526226:GBRO_RS24060
uniprot id: D0L9C2
names: Similarity
messages: Belongs to the thioredoxin family.

526226:GBRO RS06735
gene id: 526226:GBRO_RS06735
uniprot id: D0L696
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

526226:GBRO RS18040
gene id: 526226:GBRO_RS18040
uniprot id: D0LFB8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526226:GBRO RS14680
gene id: 526226:GBRO_RS14680
uniprot id: D0L9Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

526226:GBRO RS22380
gene id: 526226:GBRO_RS22380
uniprot id: D0L6T2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

526226:GBRO RS22745
gene id: 526226:GBRO_RS22745
uniprot id: D0L7C5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS08055
gene id: 526226:GBRO_RS08055
uniprot id: D0L7P6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

526226:GBRO RS12230
gene id: 526226:GBRO_RS12230
uniprot id: D0LDS8
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

526226:GBRO RS04710
gene id: 526226:GBRO_RS04710
uniprot id: D0L442
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

526226:GBRO RS12905
gene id: 526226:GBRO_RS12905
uniprot id: D0LEV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

526226:GBRO RS07970
gene id: 526226:GBRO_RS07970
uniprot id: D0L7N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS10210
gene id: 526226:GBRO_RS10210
uniprot id: D0LAK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

526226:GBRO RS20880
gene id: 526226:GBRO_RS20880
uniprot id: D0L5A0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

526226:GBRO RS18335
gene id: 526226:GBRO_RS18335
uniprot id: D0L2G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

526226:GBRO RS14975
gene id: 526226:GBRO_RS14975
uniprot id: D0LAS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

526226:GBRO RS11350
gene id: 526226:GBRO_RS11350
uniprot id: D0LCK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

526226:GBRO RS18265
gene id: 526226:GBRO_RS18265
uniprot id: D0L2F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

526226:GBRO RS04140
gene id: 526226:GBRO_RS04140
uniprot id: D0L3F2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

526226:GBRO RS23550
gene id: 526226:GBRO_RS23550
uniprot id: D0L8B9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

526226:GBRO RS13665
gene id: 526226:GBRO_RS13665
uniprot id: D0L8Y2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

526226:GBRO RS13705
gene id: 526226:GBRO_RS13705
uniprot id: D0L8Z0
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

526226:GBRO RS06570
gene id: 526226:GBRO_RS06570
uniprot id: D0L5U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

526226:GBRO RS19960
gene id: 526226:GBRO_RS19960
uniprot id: D0L4G2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS22525
gene id: 526226:GBRO_RS22525
uniprot id: D0L6W1
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

526226:GBRO RS22515
gene id: 526226:GBRO_RS22515
uniprot id: D0L6V9
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS09810
gene id: 526226:GBRO_RS09810
uniprot id: D0L9Q1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

526226:GBRO RS15925
gene id: 526226:GBRO_RS15925
uniprot id: D0LC21
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526226:GBRO RS16585
gene id: 526226:GBRO_RS16585
uniprot id: D0LD42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

526226:GBRO RS08470
gene id: 526226:GBRO_RS08470
uniprot id: D0L7X0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

526226:GBRO RS12915
gene id: 526226:GBRO_RS12915
uniprot id: D0LEV9
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS22205
gene id: 526226:GBRO_RS22205
uniprot id: D0L6P6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

526226:GBRO RS08860
gene id: 526226:GBRO_RS08860
uniprot id: D0L8P2
names: Similarity
messages: Belongs to the FPG family.

526226:GBRO RS17305
gene id: 526226:GBRO_RS17305
uniprot id: D0LE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526226:GBRO RS18120
gene id: 526226:GBRO_RS18120
uniprot id: D0L2C7
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS02305
gene id: 526226:GBRO_RS02305
uniprot id: D0LDI2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

526226:GBRO RS03350
gene id: 526226:GBRO_RS03350
uniprot id: D0L2B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

526226:GBRO RS14040
gene id: 526226:GBRO_RS14040
uniprot id: D0L951
names: Similarity
messages: Belongs to the TlyA family.

526226:GBRO RS13170
gene id: 526226:GBRO_RS13170
uniprot id: D0L7Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

526226:GBRO RS01305
gene id: 526226:GBRO_RS01305
uniprot id: D0LC89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS00620
gene id: 526226:GBRO_RS00620
uniprot id: D0LB45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).
messages: Cell membrane
messages: In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
messages: In the N-terminal section; belongs to the LPG synthetase family.

526226:GBRO RS09920
gene id: 526226:GBRO_RS09920
uniprot id: D0LAE7
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS06840
gene id: 526226:GBRO_RS06840
uniprot id: D0L6B8
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

526226:GBRO RS05265
gene id: 526226:GBRO_RS05265
uniprot id: D0L4F4
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS10465
gene id: 526226:GBRO_RS10465
uniprot id: D0LAP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

526226:GBRO RS06380
gene id: 526226:GBRO_RS06380
uniprot id: D0L5R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526226:GBRO RS04495
gene id: 526226:GBRO_RS04495
uniprot id: D0L3M4
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

526226:GBRO RS10705
gene id: 526226:GBRO_RS10705
uniprot id: D0LBJ3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

526226:GBRO RS16230
gene id: 526226:GBRO_RS16230
uniprot id: D0LCX4
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

526226:GBRO RS02915
gene id: 526226:GBRO_RS02915
uniprot id: D0LEK3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

526226:GBRO RS20240
gene id: 526226:GBRO_RS20240
uniprot id: D0L4L7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526226:GBRO RS09650
gene id: 526226:GBRO_RS09650
uniprot id: D0L9M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

526226:GBRO RS16665
gene id: 526226:GBRO_RS16665
uniprot id: D0LD59
names: Similarity
messages: Belongs to the asp23 family.

526226:GBRO RS02145
gene id: 526226:GBRO_RS02145
uniprot id: D0LDF1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

526226:GBRO RS10205
gene id: 526226:GBRO_RS10205
uniprot id: D0LAJ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

526226:GBRO RS14085
gene id: 526226:GBRO_RS14085
uniprot id: D0L957
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

526226:GBRO RS06670
gene id: 526226:GBRO_RS06670
uniprot id: D0L683
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

526226:GBRO RS00770
gene id: 526226:GBRO_RS00770
uniprot id: D0LB75
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS01520
gene id: 526226:GBRO_RS01520
uniprot id: D0LCC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

526226:GBRO RS16880
gene id: 526226:GBRO_RS16880
uniprot id: D0LDZ8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

526226:GBRO RS03235
gene id: 526226:GBRO_RS03235
uniprot id: D0L296
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

526226:GBRO RS14605
gene id: 526226:GBRO_RS14605
uniprot id: D0L9Y3
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

526226:GBRO RS18415
gene id: 526226:GBRO_RS18415
uniprot id: D0L2I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

526226:GBRO RS08460
gene id: 526226:GBRO_RS08460
uniprot id: D0L7W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

526226:GBRO RS13100
gene id: 526226:GBRO_RS13100
uniprot id: D0L778
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

526226:GBRO RS05120
gene id: 526226:GBRO_RS05120
uniprot id: D0L4C5
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS16160
gene id: 526226:GBRO_RS16160
uniprot id: D0LCW0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

526226:GBRO RS15005
gene id: 526226:GBRO_RS15005
uniprot id: D0LAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

526226:GBRO RS07990
gene id: 526226:GBRO_RS07990
uniprot id: D0L778
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

526226:GBRO RS10665
gene id: 526226:GBRO_RS10665
uniprot id: D0LBI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

526226:GBRO RS09985
gene id: 526226:GBRO_RS09985
uniprot id: D0LAF9
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS10365
gene id: 526226:GBRO_RS10365
uniprot id: D0LAN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

526226:GBRO RS10385
gene id: 526226:GBRO_RS10385
uniprot id: D0LAN5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

526226:GBRO RS10265
gene id: 526226:GBRO_RS10265
uniprot id: D0LAL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

526226:GBRO RS08090
gene id: 526226:GBRO_RS08090
uniprot id: D0L7Q3
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

526226:GBRO RS05940
gene id: 526226:GBRO_RS05940
uniprot id: D0L5H7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

526226:GBRO RS15240
gene id: 526226:GBRO_RS15240
uniprot id: D0LAY1
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

526226:GBRO RS17975
gene id: 526226:GBRO_RS17975
uniprot id: D0LFA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

526226:GBRO RS16715
gene id: 526226:GBRO_RS16715
uniprot id: D0LD69
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS06075
gene id: 526226:GBRO_RS06075
uniprot id: D0L5K1
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

526226:GBRO RS18325
gene id: 526226:GBRO_RS18325
uniprot id: D0L2G6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526226:GBRO RS09620
gene id: 526226:GBRO_RS09620
uniprot id: D0L9L5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

526226:GBRO RS17455
gene id: 526226:GBRO_RS17455
uniprot id: D0LF05
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

526226:GBRO RS23740
gene id: 526226:GBRO_RS23740
uniprot id: D0L8F5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

526226:GBRO RS09340
gene id: 526226:GBRO_RS09340
uniprot id: D0L9G3
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

526226:GBRO RS02430
gene id: 526226:GBRO_RS02430
uniprot id: D0LDK2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

526226:GBRO RS21895
gene id: 526226:GBRO_RS21895
uniprot id: D0L662
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS18460
gene id: 526226:GBRO_RS18460
uniprot id: D0L2J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

526226:GBRO RS17860
gene id: 526226:GBRO_RS17860
uniprot id: D0LF83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

526226:GBRO RS18105
gene id: 526226:GBRO_RS18105
uniprot id: D0L2C4
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

526226:GBRO RS06685
gene id: 526226:GBRO_RS06685
uniprot id: D0L686
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS18430
gene id: 526226:GBRO_RS18430
uniprot id: D0L2I8
names: Similarity
messages: Belongs to the peptidase M13 family.

526226:GBRO RS15000
gene id: 526226:GBRO_RS15000
uniprot id: D0LAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

526226:GBRO RS05010
gene id: 526226:GBRO_RS05010
uniprot id: D0L4A3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

526226:GBRO RS16490
gene id: 526226:GBRO_RS16490
uniprot id: D0LD24
names: Similarity
messages: Belongs to the LOG family.

526226:GBRO RS21415
gene id: 526226:GBRO_RS21415
uniprot id: D0L5W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.
messages: Secreted

526226:GBRO RS11365
gene id: 526226:GBRO_RS11365
uniprot id: D0LCK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

526226:GBRO RS10335
gene id: 526226:GBRO_RS10335
uniprot id: D0LAM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

526226:GBRO RS07630
gene id: 526226:GBRO_RS07630
uniprot id: D0L746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526226:GBRO RS22375
gene id: 526226:GBRO_RS22375
uniprot id: D0L6T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

526226:GBRO RS03395
gene id: 526226:GBRO_RS03395
uniprot id: D0L2N7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS05235
gene id: 526226:GBRO_RS05235
uniprot id: D0L4E8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

526226:GBRO RS14695
gene id: 526226:GBRO_RS14695
uniprot id: D0LA01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

526226:GBRO RS12655
gene id: 526226:GBRO_RS12655
uniprot id: D0LER1
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

526226:GBRO RS01530
gene id: 526226:GBRO_RS01530
uniprot id: D0LCD0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

526226:GBRO RS15185
gene id: 526226:GBRO_RS15185
uniprot id: D0LAX0
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

526226:GBRO RS12545
gene id: 526226:GBRO_RS12545
uniprot id: D0LEP0
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS09675
gene id: 526226:GBRO_RS09675
uniprot id: D0L9M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

526226:GBRO RS01195
gene id: 526226:GBRO_RS01195
uniprot id: D0LC68
names: Similarity
messages: Belongs to the AHA1 family.

526226:GBRO RS21045
gene id: 526226:GBRO_RS21045
uniprot id: D0L5C6
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS01145
gene id: 526226:GBRO_RS01145
uniprot id: D0LBF1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526226:GBRO RS24055
gene id: 526226:GBRO_RS24055
uniprot id: D0L9C1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

526226:GBRO RS07040
gene id: 526226:GBRO_RS07040
uniprot id: D0L6F9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

526226:GBRO RS14145
gene id: 526226:GBRO_RS14145
uniprot id: D0L969
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

526226:GBRO RS00125
gene id: 526226:GBRO_RS00125
uniprot id: D0LA53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

526226:GBRO RS04815
gene id: 526226:GBRO_RS04815
uniprot id: D0L463
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

526226:GBRO RS08705
gene id: 526226:GBRO_RS08705
uniprot id: D0L8L0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS19215
gene id: 526226:GBRO_RS19215
uniprot id: D0L3B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS14670
gene id: 526226:GBRO_RS14670
uniprot id: D0L9Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

526226:GBRO RS17230
gene id: 526226:GBRO_RS17230
uniprot id: D0LE65
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS22255
gene id: 526226:GBRO_RS22255
uniprot id: D0L6Q6
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS11450
gene id: 526226:GBRO_RS11450
uniprot id: D0LCM6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

526226:GBRO RS03315
gene id: 526226:GBRO_RS03315
uniprot id: D0L2B2
names: Similarity
messages: Belongs to the AAA ATPase family.

526226:GBRO RS11455
gene id: 526226:GBRO_RS11455
uniprot id: D0LCM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

526226:GBRO RS22095
gene id: 526226:GBRO_RS22095
uniprot id: D0L6M3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS06385
gene id: 526226:GBRO_RS06385
uniprot id: D0L5R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526226:GBRO RS11260
gene id: 526226:GBRO_RS11260
uniprot id: D0LCJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

526226:GBRO RS12090
gene id: 526226:GBRO_RS12090
uniprot id: D0LDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

526226:GBRO RS21845
gene id: 526226:GBRO_RS21845
uniprot id: D0L652
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

526226:GBRO RS04190
gene id: 526226:GBRO_RS04190
uniprot id: D0L3G1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

526226:GBRO RS13735
gene id: 526226:GBRO_RS13735
uniprot id: D0L8Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

526226:GBRO RS04095
gene id: 526226:GBRO_RS04095
uniprot id: D0L3E3
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS23925
gene id: 526226:GBRO_RS23925
uniprot id: D0L994
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS13880
gene id: 526226:GBRO_RS13880
uniprot id: D0L923
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

526226:GBRO RS09120
gene id: 526226:GBRO_RS09120
uniprot id: D0L8U1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

526226:GBRO RS00455
gene id: 526226:GBRO_RS00455
uniprot id: D0LAB4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526226:GBRO RS13410
gene id: 526226:GBRO_RS13410
uniprot id: D0L829
names: Similarity
messages: Belongs to the cytochrome P450 family.

526226:GBRO RS22405
gene id: 526226:GBRO_RS22405
uniprot id: D0L6T7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

526226:GBRO RS19110
gene id: 526226:GBRO_RS19110
uniprot id: D0L393
names: Similarity
messages: Belongs to the cytochrome P450 family.

526226:GBRO RS00490
gene id: 526226:GBRO_RS00490
uniprot id: D0LAC1
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS01055
gene id: 526226:GBRO_RS01055
uniprot id: D0LBD4
names: Similarity
messages: Belongs to the Dps family.

526226:GBRO RS00395
gene id: 526226:GBRO_RS00395
uniprot id: D0LAA3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

526226:GBRO RS12250
gene id: 526226:GBRO_RS12250
uniprot id: D0LDT2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

526226:GBRO RS02030
gene id: 526226:GBRO_RS02030
uniprot id: D0LDC8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

526226:GBRO RS14095
gene id: 526226:GBRO_RS14095
uniprot id: D0L959
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

526226:GBRO RS11940
gene id: 526226:GBRO_RS11940
uniprot id: D0LDM0
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

526226:GBRO RS07255
gene id: 526226:GBRO_RS07255
uniprot id: D0L6X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

526226:GBRO RS02765
gene id: 526226:GBRO_RS02765
uniprot id: D0LEH5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

526226:GBRO RS18055
gene id: 526226:GBRO_RS18055
uniprot id: D0LFC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

526226:GBRO RS04680
gene id: 526226:GBRO_RS04680
uniprot id: D0L435
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

526226:GBRO RS15695
gene id: 526226:GBRO_RS15695
uniprot id: D0LBX5
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS03415
gene id: 526226:GBRO_RS03415
uniprot id: D0L2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

526226:GBRO RS08100
gene id: 526226:GBRO_RS08100
uniprot id: D0L7Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

526226:GBRO RS04900
gene id: 526226:GBRO_RS04900
uniprot id: D0L480
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS09060
gene id: 526226:GBRO_RS09060
uniprot id: D0L8S9
names: Similarity
messages: Belongs to the AccD/PCCB family.

526226:GBRO RS10660
gene id: 526226:GBRO_RS10660
uniprot id: D0LBI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

526226:GBRO RS10560
gene id: 526226:GBRO_RS10560
uniprot id: D0LBG5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

526226:GBRO RS07280
gene id: 526226:GBRO_RS07280
uniprot id: D0L6Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

526226:GBRO RS11585
gene id: 526226:GBRO_RS11585
uniprot id: D0LCQ3
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS00870
gene id: 526226:GBRO_RS00870
uniprot id: D0LB97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

526226:GBRO RS00010
gene id: 526226:GBRO_RS00010
uniprot id: D0LA33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

526226:GBRO RS15170
gene id: 526226:GBRO_RS15170
uniprot id: D0LAW7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS00025
gene id: 526226:GBRO_RS00025
uniprot id: D0LA36
names: Similarity
messages: Belongs to the UPF0232 family.

526226:GBRO RS13225
gene id: 526226:GBRO_RS13225
uniprot id: D0L7Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

526226:GBRO RS06060
gene id: 526226:GBRO_RS06060
uniprot id: D0L5J8
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

526226:GBRO RS04970
gene id: 526226:GBRO_RS04970
uniprot id: D0L495
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526226:GBRO RS20840
gene id: 526226:GBRO_RS20840
uniprot id: D0L593
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS21210
gene id: 526226:GBRO_RS21210
uniprot id: D0L5F6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

526226:GBRO RS13640
gene id: 526226:GBRO_RS13640
uniprot id: D0L8X7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

526226:GBRO RS15920
gene id: 526226:GBRO_RS15920
uniprot id: D0LC20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

526226:GBRO RS14325
gene id: 526226:GBRO_RS14325
uniprot id: D0L9T0
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS07430
gene id: 526226:GBRO_RS07430
uniprot id: D0L707
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

526226:GBRO RS08250
gene id: 526226:GBRO_RS08250
uniprot id: D0L7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

526226:GBRO RS07560
gene id: 526226:GBRO_RS07560
uniprot id: D0L733
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS13030
gene id: 526226:GBRO_RS13030
uniprot id: D0LEY3
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS18485
gene id: 526226:GBRO_RS18485
uniprot id: D0L2J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

526226:GBRO RS03995
gene id: 526226:GBRO_RS03995
uniprot id: D0L2Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

526226:GBRO RS12175
gene id: 526226:GBRO_RS12175
uniprot id: D0LDR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

526226:GBRO RS10380
gene id: 526226:GBRO_RS10380
uniprot id: D0LAN4
names: Similarity
messages: Belongs to the UPF0102 family.

526226:GBRO RS20855
gene id: 526226:GBRO_RS20855
uniprot id: D0L596
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

526226:GBRO RS02625
gene id: 526226:GBRO_RS02625
uniprot id: D0LEE6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

526226:GBRO RS20230
gene id: 526226:GBRO_RS20230
uniprot id: D0L4L5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

526226:GBRO RS15090
gene id: 526226:GBRO_RS15090
uniprot id: D0LAV1
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

526226:GBRO RS12560
gene id: 526226:GBRO_RS12560
uniprot id: D0LEP3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS18310
gene id: 526226:GBRO_RS18310
uniprot id: D0L2G4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

526226:GBRO RS06820
gene id: 526226:GBRO_RS06820
uniprot id: D0L6B4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS20415
gene id: 526226:GBRO_RS20415
uniprot id: D0L4P8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526226:GBRO RS14765
gene id: 526226:GBRO_RS14765
uniprot id: D0LA15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS00015
gene id: 526226:GBRO_RS00015
uniprot id: D0LA34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

526226:GBRO RS18655
gene id: 526226:GBRO_RS18655
uniprot id: D0L2N2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

526226:GBRO RS17705
gene id: 526226:GBRO_RS17705
uniprot id: D0LF54
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

526226:GBRO RS12515
gene id: 526226:GBRO_RS12515
uniprot id: D0LEN4
names: Similarity
messages: Belongs to the catalase family.

526226:GBRO RS04550
gene id: 526226:GBRO_RS04550
uniprot id: D0L3N5
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

526226:GBRO RS15035
gene id: 526226:GBRO_RS15035
uniprot id: D0LAU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

526226:GBRO RS08180
gene id: 526226:GBRO_RS08180
uniprot id: D0L7S1
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.

526226:GBRO RS10300
gene id: 526226:GBRO_RS10300
uniprot id: D0LAL8
names: Similarity
messages: Belongs to the P(II) protein family.

526226:GBRO RS13460
gene id: 526226:GBRO_RS13460
uniprot id: D0L838
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

526226:GBRO RS12810
gene id: 526226:GBRO_RS12810
uniprot id: D0LEU1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

526226:GBRO RS12520
gene id: 526226:GBRO_RS12520
uniprot id: D0LEN5
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

526226:GBRO RS17580
gene id: 526226:GBRO_RS17580
uniprot id: D0LF30
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS18735
gene id: 526226:GBRO_RS18735
uniprot id: D0L318
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

526226:GBRO RS04715
gene id: 526226:GBRO_RS04715
uniprot id: D0L443
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS07410
gene id: 526226:GBRO_RS07410
uniprot id: D0L704
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

526226:GBRO RS11675
gene id: 526226:GBRO_RS11675
uniprot id: D0LCR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

526226:GBRO RS11700
gene id: 526226:GBRO_RS11700
uniprot id: D0LCS4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

526226:GBRO RS10415
gene id: 526226:GBRO_RS10415
uniprot id: D0LAP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

526226:GBRO RS00030
gene id: 526226:GBRO_RS00030
uniprot id: D0LA37
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

526226:GBRO RS16405
gene id: 526226:GBRO_RS16405
uniprot id: D0LD06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

526226:GBRO RS10310
gene id: 526226:GBRO_RS10310
uniprot id: D0LAM0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

526226:GBRO RS07680
gene id: 526226:GBRO_RS07680
uniprot id: D0L756
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

526226:GBRO RS11105
gene id: 526226:GBRO_RS11105
uniprot id: D0LBS2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

526226:GBRO RS08525
gene id: 526226:GBRO_RS08525
uniprot id: D0L8H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

526226:GBRO RS14970
gene id: 526226:GBRO_RS14970
uniprot id: D0LAS8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

526226:GBRO RS12235
gene id: 526226:GBRO_RS12235
uniprot id: D0LDS9
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

526226:GBRO RS14470
gene id: 526226:GBRO_RS14470
uniprot id: D0L9V6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526226:GBRO RS04765
gene id: 526226:GBRO_RS04765
uniprot id: D0L453
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

526226:GBRO RS18970
gene id: 526226:GBRO_RS18970
uniprot id: D0L365
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS03025
gene id: 526226:GBRO_RS03025
uniprot id: D0LEM5
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

526226:GBRO RS18995
gene id: 526226:GBRO_RS18995
uniprot id: D0L370
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

526226:GBRO RS03695
gene id: 526226:GBRO_RS03695
uniprot id: D0L2U0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

526226:GBRO RS08255
gene id: 526226:GBRO_RS08255
uniprot id: D0L7T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

526226:GBRO RS17195
gene id: 526226:GBRO_RS17195
uniprot id: D0LE58
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

526226:GBRO RS16480
gene id: 526226:GBRO_RS16480
uniprot id: D0LD22
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

526226:GBRO RS11740
gene id: 526226:GBRO_RS11740
uniprot id: D0LCT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

526226:GBRO RS12000
gene id: 526226:GBRO_RS12000
uniprot id: D0LDN2
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS11565
gene id: 526226:GBRO_RS11565
uniprot id: D0LCP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

526226:GBRO RS12900
gene id: 526226:GBRO_RS12900
uniprot id: D0LEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

526226:GBRO RS13655
gene id: 526226:GBRO_RS13655
uniprot id: D0L8Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

526226:GBRO RS15660
gene id: 526226:GBRO_RS15660
uniprot id: D0LBW8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

526226:GBRO RS00355
gene id: 526226:GBRO_RS00355
uniprot id: D0LA96
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

526226:GBRO RS01415
gene id: 526226:GBRO_RS01415
uniprot id: D0LCA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

526226:GBRO RS23920
gene id: 526226:GBRO_RS23920
uniprot id: D0L993
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS00475
gene id: 526226:GBRO_RS00475
uniprot id: D0LAB8
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

526226:GBRO RS17495
gene id: 526226:GBRO_RS17495
uniprot id: D0LF13
names: Similarity
messages: Belongs to the DEAD box helicase family.

526226:GBRO RS18900
gene id: 526226:GBRO_RS18900
uniprot id: D0L351
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

526226:GBRO RS19465
gene id: 526226:GBRO_RS19465
uniprot id: D0L3U1
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

526226:GBRO RS14100
gene id: 526226:GBRO_RS14100
uniprot id: D0L960
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

526226:GBRO RS07530
gene id: 526226:GBRO_RS07530
uniprot id: D0L727
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS05550
gene id: 526226:GBRO_RS05550
uniprot id: D0L4Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

526226:GBRO RS07540
gene id: 526226:GBRO_RS07540
uniprot id: D0L729
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

526226:GBRO RS13010
gene id: 526226:GBRO_RS13010
uniprot id: D0LEX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

526226:GBRO RS19015
gene id: 526226:GBRO_RS19015
uniprot id: D0L374
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

526226:GBRO RS09960
gene id: 526226:GBRO_RS09960
uniprot id: D0LAF4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS11770
gene id: 526226:GBRO_RS11770
uniprot id: D0LCT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

526226:GBRO RS20205
gene id: 526226:GBRO_RS20205
uniprot id: D0L4L0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS11830
gene id: 526226:GBRO_RS11830
uniprot id: D0LCV0
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS11800
gene id: 526226:GBRO_RS11800
uniprot id: D0LCU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

526226:GBRO RS03800
gene id: 526226:GBRO_RS03800
uniprot id: D0L2W1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

526226:GBRO RS20125
gene id: 526226:GBRO_RS20125
uniprot id: D0L4J4
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

526226:GBRO RS03245
gene id: 526226:GBRO_RS03245
uniprot id: D0L298
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

526226:GBRO RS06605
gene id: 526226:GBRO_RS06605
uniprot id: D0L671
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

526226:GBRO RS12640
gene id: 526226:GBRO_RS12640
uniprot id: D0LEQ8
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS14105
gene id: 526226:GBRO_RS14105
uniprot id: D0L961
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

526226:GBRO RS03155
gene id: 526226:GBRO_RS03155
uniprot id: D0L280
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

526226:GBRO RS18775
gene id: 526226:GBRO_RS18775
uniprot id: D0L326
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

526226:GBRO RS02100
gene id: 526226:GBRO_RS02100
uniprot id: D0LDE2
names: Similarity
messages: Belongs to the CFA/CMAS family.

526226:GBRO RS10200
gene id: 526226:GBRO_RS10200
uniprot id: D0LAJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

526226:GBRO RS04090
gene id: 526226:GBRO_RS04090
uniprot id: D0L3E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

526226:GBRO RS04200
gene id: 526226:GBRO_RS04200
uniprot id: D0L3G3
names: Similarity
messages: Belongs to the peptidase M18 family.

526226:GBRO RS01940
gene id: 526226:GBRO_RS01940
uniprot id: D0LDB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

526226:GBRO RS07620
gene id: 526226:GBRO_RS07620
uniprot id: D0L744
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

526226:GBRO RS16170
gene id: 526226:GBRO_RS16170
uniprot id: D0LCW2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

526226:GBRO RS07685
gene id: 526226:GBRO_RS07685
uniprot id: D0L757
names: Similarity
messages: Belongs to the EfeM/EfeO family.

526226:GBRO RS21395
gene id: 526226:GBRO_RS21395
uniprot id: D0L5W5
names: Similarity
messages: Belongs to the YciI family.

526226:GBRO RS06325
gene id: 526226:GBRO_RS06325
uniprot id: D0L5P8
names: Subcellular Location Annotation
messages: Cell membrane

526226:GBRO RS15770
gene id: 526226:GBRO_RS15770
uniprot id: D0LBZ0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

526226:GBRO RS09125
gene id: 526226:GBRO_RS09125
uniprot id: D0L8U2
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

526226:GBRO RS16040
gene id: 526226:GBRO_RS16040
uniprot id: D0LC42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

526226:GBRO RS07920
gene id: 526226:GBRO_RS07920
uniprot id: D0L7M0
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS14565
gene id: 526226:GBRO_RS14565
uniprot id: D0L9X5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

526226:GBRO RS02900
gene id: 526226:GBRO_RS02900
uniprot id: D0LEK0
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS07185
gene id: 526226:GBRO_RS07185
uniprot id: D0L6I9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

526226:GBRO RS07170
gene id: 526226:GBRO_RS07170
uniprot id: D0L6I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

526226:GBRO RS05485
gene id: 526226:GBRO_RS05485
uniprot id: D0L4W7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

526226:GBRO RS10570
gene id: 526226:GBRO_RS10570
uniprot id: D0LBG7
names: Similarity
messages: Belongs to the MQO family.

526226:GBRO RS18350
gene id: 526226:GBRO_RS18350
uniprot id: D0L2H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

526226:GBRO RS08480
gene id: 526226:GBRO_RS08480
uniprot id: D0L7X2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

526226:GBRO RS06435
gene id: 526226:GBRO_RS06435
uniprot id: D0L5D9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

526226:GBRO RS03475
gene id: 526226:GBRO_RS03475
uniprot id: D0L2Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

526226:GBRO RS21875
gene id: 526226:GBRO_RS21875
uniprot id: D0L658
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.
messages: Homodimer.

526226:GBRO RS14950
gene id: 526226:GBRO_RS14950
uniprot id: D0LAS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

526226:GBRO RS07550
gene id: 526226:GBRO_RS07550
uniprot id: D0L731
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS09360
gene id: 526226:GBRO_RS09360
uniprot id: D0L9G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

526226:GBRO RS15385
gene id: 526226:GBRO_RS15385
uniprot id: D0LB09
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

526226:GBRO RS01150
gene id: 526226:GBRO_RS01150
uniprot id: D0LBF2
names: Caution
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS10990
gene id: 526226:GBRO_RS10990
uniprot id: D0LBP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

526226:GBRO RS18050
gene id: 526226:GBRO_RS18050
uniprot id: D0LFC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

526226:GBRO RS11005
gene id: 526226:GBRO_RS11005
uniprot id: D0LBQ1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

526226:GBRO RS05040
gene id: 526226:GBRO_RS05040
uniprot id: D0L4A9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

526226:GBRO RS09025
gene id: 526226:GBRO_RS09025
uniprot id: D0L8S3
names: Similarity
messages: Belongs to the SufE family.

526226:GBRO RS18320
gene id: 526226:GBRO_RS18320
uniprot id: D0L2G5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

526226:GBRO RS11665
gene id: 526226:GBRO_RS11665
uniprot id: D0LCR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

526226:GBRO RS18090
gene id: 526226:GBRO_RS18090
uniprot id: D0L2C1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

526226:GBRO RS21585
gene id: 526226:GBRO_RS21585
uniprot id: D0L602
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

526226:GBRO RS02270
gene id: 526226:GBRO_RS02270
uniprot id: D0LDH5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

526226:GBRO RS04620
gene id: 526226:GBRO_RS04620
uniprot id: D0L3P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

526226:GBRO RS09670
gene id: 526226:GBRO_RS09670
uniprot id: D0L9M5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

526226:GBRO RS07195
gene id: 526226:GBRO_RS07195
uniprot id: D0L6J1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

526226:GBRO RS10690
gene id: 526226:GBRO_RS10690
uniprot id: D0LBJ0
names: Subcellular Location Annotation
messages: Membrane

526226:GBRO RS00780
gene id: 526226:GBRO_RS00780
uniprot id: D0LB78
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

526226:GBRO RS05560
gene id: 526226:GBRO_RS05560
uniprot id: D0L4Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

526226:GBRO RS04120
gene id: 526226:GBRO_RS04120
uniprot id: D0L3E8
names: Similarity
messages: Belongs to the CsoR family.

526226:GBRO RS03190
gene id: 526226:GBRO_RS03190
uniprot id: D0L288
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

526226:GBRO RS16650
gene id: 526226:GBRO_RS16650
uniprot id: D0LD56
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

526226:GBRO RS11750
gene id: 526226:GBRO_RS11750
uniprot id: D0LCT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

526226:GBRO RS14600
gene id: 526226:GBRO_RS14600
uniprot id: D0L9Y2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

526226:GBRO RS07465
gene id: 526226:GBRO_RS07465
uniprot id: D0L714
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

526226:GBRO RS16130
gene id: 526226:GBRO_RS16130
uniprot id: D0LC60
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

526226:GBRO RS01855
gene id: 526226:GBRO_RS01855
uniprot id: D0LD93
names: Similarity
messages: Belongs to the TPP enzyme family.

526226:GBRO RS10325
gene id: 526226:GBRO_RS10325
uniprot id: D0LAM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

526226:GBRO RS08445
gene id: 526226:GBRO_RS08445
uniprot id: D0L7W5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

526226:GBRO RS10780
gene id: 526226:GBRO_RS10780
uniprot id: D0LBK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

526226:GBRO RS12105
gene id: 526226:GBRO_RS12105
uniprot id: D0LDQ2
names: Similarity
messages: Belongs to the UPF0098 family.

526226:GBRO RS14030
gene id: 526226:GBRO_RS14030
uniprot id: D0L949
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.