525909:AFER RS08890
gene id: 525909:AFER_RS08890
uniprot id: C7M0X6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

525909:AFER RS05305
gene id: 525909:AFER_RS05305
uniprot id: C7LZ15
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS02730
gene id: 525909:AFER_RS02730
uniprot id: C7M3A2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

525909:AFER RS01665
gene id: 525909:AFER_RS01665
uniprot id: C7M2P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

525909:AFER RS03355
gene id: 525909:AFER_RS03355
uniprot id: C7LXZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS02075
gene id: 525909:AFER_RS02075
uniprot id: C7M2X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

525909:AFER RS01670
gene id: 525909:AFER_RS01670
uniprot id: C7M2P8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

525909:AFER RS04640
gene id: 525909:AFER_RS04640
uniprot id: C7LYN7
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

525909:AFER RS09545
gene id: 525909:AFER_RS09545
uniprot id: C7M1B4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

525909:AFER RS06670
gene id: 525909:AFER_RS06670
uniprot id: C7LZR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

525909:AFER RS02095
gene id: 525909:AFER_RS02095
uniprot id: C7M2X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

525909:AFER RS04865
gene id: 525909:AFER_RS04865
uniprot id: C7LYS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

525909:AFER RS02960
gene id: 525909:AFER_RS02960
uniprot id: C7M3E0
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS05750
gene id: 525909:AFER_RS05750
uniprot id: C7LZ98
names: Similarity
messages: Belongs to the phosphohexose mutase family.

525909:AFER RS02040
gene id: 525909:AFER_RS02040
uniprot id: C7M2W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

525909:AFER RS05810
gene id: 525909:AFER_RS05810
uniprot id: C7LZB0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS07095
gene id: 525909:AFER_RS07095
uniprot id: C7LZZ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

525909:AFER RS09090
gene id: 525909:AFER_RS09090
uniprot id: C7M126
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

525909:AFER RS05590
gene id: 525909:AFER_RS05590
uniprot id: C7LZ66
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

525909:AFER RS07625
gene id: 525909:AFER_RS07625
uniprot id: C7M089
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS01155
gene id: 525909:AFER_RS01155
uniprot id: C7M296
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

525909:AFER RS08435
gene id: 525909:AFER_RS08435
uniprot id: C7M0N8
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS04380
gene id: 525909:AFER_RS04380
uniprot id: C7LYI7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

525909:AFER RS10120
gene id: 525909:AFER_RS10120
uniprot id: C7M1W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

525909:AFER RS10880
gene id: 525909:AFER_RS10880
uniprot id: C7LYA7
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

525909:AFER RS03725
gene id: 525909:AFER_RS03725
uniprot id: C7LY66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

525909:AFER RS02425
gene id: 525909:AFER_RS02425
uniprot id: C7M345
names: Similarity
messages: Belongs to the peptidase U62 family.

525909:AFER RS05755
gene id: 525909:AFER_RS05755
uniprot id: C7LZ99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

525909:AFER RS01810
gene id: 525909:AFER_RS01810
uniprot id: C7M2S5
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

525909:AFER RS08200
gene id: 525909:AFER_RS08200
uniprot id: C7M0J5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

525909:AFER RS02740
gene id: 525909:AFER_RS02740
uniprot id: C7M3A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

525909:AFER RS06120
gene id: 525909:AFER_RS06120
uniprot id: C7LZG4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

525909:AFER RS03255
gene id: 525909:AFER_RS03255
uniprot id: C7LXX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

525909:AFER RS06725
gene id: 525909:AFER_RS06725
uniprot id: C7LZT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

525909:AFER RS10240
gene id: 525909:AFER_RS10240
uniprot id: C7M1Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

525909:AFER RS02600
gene id: 525909:AFER_RS02600
uniprot id: C7M380
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS08880
gene id: 525909:AFER_RS08880
uniprot id: C7M0X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

525909:AFER RS10290
gene id: 525909:AFER_RS10290
uniprot id: C7M2A2
names: Similarity
messages: Belongs to the glutamate synthase family.

525909:AFER RS06055
gene id: 525909:AFER_RS06055
uniprot id: C7LZF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

525909:AFER RS00880
gene id: 525909:AFER_RS00880
uniprot id: C7M243
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

525909:AFER RS11580
gene id: 525909:AFER_RS11580
uniprot id: C7LYG8
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

525909:AFER RS05170
gene id: 525909:AFER_RS05170
uniprot id: C7LYY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

525909:AFER RS02030
gene id: 525909:AFER_RS02030
uniprot id: C7M2W6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

525909:AFER RS03265
gene id: 525909:AFER_RS03265
uniprot id: C7LXY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

525909:AFER RS01835
gene id: 525909:AFER_RS01835
uniprot id: C7M2T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

525909:AFER RS11310
gene id: 525909:AFER_RS11310
uniprot id: C7M148
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS09470
gene id: 525909:AFER_RS09470
uniprot id: C7M1A0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

525909:AFER RS09270
gene id: 525909:AFER_RS09270
uniprot id: C7M161
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

525909:AFER RS12430
gene id: 525909:AFER_RS12430
uniprot id: C7M0S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

525909:AFER RS10780
gene id: 525909:AFER_RS10780
uniprot id: C7M355
names: Similarity
messages: Belongs to the sterol desaturase family.

525909:AFER RS02150
gene id: 525909:AFER_RS02150
uniprot id: C7M2Z0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

525909:AFER RS02060
gene id: 525909:AFER_RS02060
uniprot id: C7M2X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

525909:AFER RS08605
gene id: 525909:AFER_RS08605
uniprot id: C7M0R9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

525909:AFER RS05420
gene id: 525909:AFER_RS05420
uniprot id: C7LZ38
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS02100
gene id: 525909:AFER_RS02100
uniprot id: C7M2Y0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

525909:AFER RS08300
gene id: 525909:AFER_RS08300
uniprot id: C7M0L5
names: Similarity
messages: Belongs to the TPP enzyme family.

525909:AFER RS09065
gene id: 525909:AFER_RS09065
uniprot id: C7M112
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

525909:AFER RS08970
gene id: 525909:AFER_RS08970
uniprot id: C7M0Z4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

525909:AFER RS01940
gene id: 525909:AFER_RS01940
uniprot id: C7M2V2
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS02550
gene id: 525909:AFER_RS02550
uniprot id: C7M369
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS09415
gene id: 525909:AFER_RS09415
uniprot id: C7M189
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

525909:AFER RS07840
gene id: 525909:AFER_RS07840
uniprot id: C7M0D1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

525909:AFER RS00965
gene id: 525909:AFER_RS00965
uniprot id: C7M261
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS03310
gene id: 525909:AFER_RS03310
uniprot id: C7LXZ0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

525909:AFER RS02455
gene id: 525909:AFER_RS02455
uniprot id: C7M352
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

525909:AFER RS03130
gene id: 525909:AFER_RS03130
uniprot id: C7LXV8
names: Similarity
messages: Belongs to the peptidase S45 family.

525909:AFER RS01320
gene id: 525909:AFER_RS01320
uniprot id: C7M2I0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS08965
gene id: 525909:AFER_RS08965
uniprot id: C7M0Z3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

525909:AFER RS01910
gene id: 525909:AFER_RS01910
uniprot id: C7M2U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

525909:AFER RS04990
gene id: 525909:AFER_RS04990
uniprot id: C7LYV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

525909:AFER RS08035
gene id: 525909:AFER_RS08035
uniprot id: C7M0G4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

525909:AFER RS00575
gene id: 525909:AFER_RS00575
uniprot id: C7M1N3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS09575
gene id: 525909:AFER_RS09575
uniprot id: C7M1C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

525909:AFER RS03980
gene id: 525909:AFER_RS03980
uniprot id: C7LYB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

525909:AFER RS05705
gene id: 525909:AFER_RS05705
uniprot id: C7LZ89
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

525909:AFER RS09935
gene id: 525909:AFER_RS09935
uniprot id: C7M1S9
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS08720
gene id: 525909:AFER_RS08720
uniprot id: C7M0U1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

525909:AFER RS01575
gene id: 525909:AFER_RS01575
uniprot id: C7M2M9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

525909:AFER RS03190
gene id: 525909:AFER_RS03190
uniprot id: C7LXW8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

525909:AFER RS02035
gene id: 525909:AFER_RS02035
uniprot id: C7M2W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

525909:AFER RS01295
gene id: 525909:AFER_RS01295
uniprot id: C7M2H5
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

525909:AFER RS11160
gene id: 525909:AFER_RS11160
uniprot id: C7M068
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

525909:AFER RS02340
gene id: 525909:AFER_RS02340
uniprot id: C7M329
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

525909:AFER RS04675
gene id: 525909:AFER_RS04675
uniprot id: C7LYP4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets.

525909:AFER RS04665
gene id: 525909:AFER_RS04665
uniprot id: C7LYP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

525909:AFER RS02245
gene id: 525909:AFER_RS02245
uniprot id: C7M310
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

525909:AFER RS06660
gene id: 525909:AFER_RS06660
uniprot id: C7LZR6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

525909:AFER RS07420
gene id: 525909:AFER_RS07420
uniprot id: C7M053
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS04430
gene id: 525909:AFER_RS04430
uniprot id: C7LYJ5
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS06530
gene id: 525909:AFER_RS06530
uniprot id: C7LZP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

525909:AFER RS12700
gene id: 525909:AFER_RS12700
uniprot id: C7M110
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

525909:AFER RS00650
gene id: 525909:AFER_RS00650
uniprot id: C7M1Z8
names: Subunit
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

525909:AFER RS03270
gene id: 525909:AFER_RS03270
uniprot id: C7LXY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

525909:AFER RS04995
gene id: 525909:AFER_RS04995
uniprot id: C7LYV2
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS02070
gene id: 525909:AFER_RS02070
uniprot id: C7M2X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

525909:AFER RS10190
gene id: 525909:AFER_RS10190
uniprot id: C7M1X5
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS03245
gene id: 525909:AFER_RS03245
uniprot id: C7LXX7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS09570
gene id: 525909:AFER_RS09570
uniprot id: C7M1B9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

525909:AFER RS09280
gene id: 525909:AFER_RS09280
uniprot id: C7M163
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

525909:AFER RS06650
gene id: 525909:AFER_RS06650
uniprot id: C7LZR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

525909:AFER RS00640
gene id: 525909:AFER_RS00640
uniprot id: C7M1Z6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

525909:AFER RS10695
gene id: 525909:AFER_RS10695
uniprot id: C7M279
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

525909:AFER RS04190
gene id: 525909:AFER_RS04190
uniprot id: C7LYF0
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

525909:AFER RS00775
gene id: 525909:AFER_RS00775
uniprot id: C7M222
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

525909:AFER RS10765
gene id: 525909:AFER_RS10765
uniprot id: C7M346
names: Similarity
messages: Belongs to the peptidase U62 family.

525909:AFER RS08160
gene id: 525909:AFER_RS08160
uniprot id: C7M0I7
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS04840
gene id: 525909:AFER_RS04840
uniprot id: C7LYS1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

525909:AFER RS06665
gene id: 525909:AFER_RS06665
uniprot id: C7LZR7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

525909:AFER RS04930
gene id: 525909:AFER_RS04930
uniprot id: C7LYT9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

525909:AFER RS07925
gene id: 525909:AFER_RS07925
uniprot id: C7M0E6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

525909:AFER RS06220
gene id: 525909:AFER_RS06220
uniprot id: C7LZI3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

525909:AFER RS01720
gene id: 525909:AFER_RS01720
uniprot id: C7M2Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

525909:AFER RS03985
gene id: 525909:AFER_RS03985
uniprot id: C7LYB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

525909:AFER RS08390
gene id: 525909:AFER_RS08390
uniprot id: C7M0N1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

525909:AFER RS00265
gene id: 525909:AFER_RS00265
uniprot id: C7M1H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

525909:AFER RS06050
gene id: 525909:AFER_RS06050
uniprot id: C7LZF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

525909:AFER RS08595
gene id: 525909:AFER_RS08595
uniprot id: C7M0R7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS05785
gene id: 525909:AFER_RS05785
uniprot id: C7LZA5
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS00230
gene id: 525909:AFER_RS00230
uniprot id: C7M1H1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

525909:AFER RS00685
gene id: 525909:AFER_RS00685
uniprot id: C7M205
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

525909:AFER RS09605
gene id: 525909:AFER_RS09605
uniprot id: C7M1C5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

525909:AFER RS01370
gene id: 525909:AFER_RS01370
uniprot id: C7M2J0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

525909:AFER RS04110
gene id: 525909:AFER_RS04110
uniprot id: C7LYD6
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

525909:AFER RS08080
gene id: 525909:AFER_RS08080
uniprot id: C7M0H3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

525909:AFER RS09805
gene id: 525909:AFER_RS09805
uniprot id: C7M1Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

525909:AFER RS08625
gene id: 525909:AFER_RS08625
uniprot id: C7M0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

525909:AFER RS03940
gene id: 525909:AFER_RS03940
uniprot id: C7LYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

525909:AFER RS02855
gene id: 525909:AFER_RS02855
uniprot id: C7M3C0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

525909:AFER RS08240
gene id: 525909:AFER_RS08240
uniprot id: C7M0K3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

525909:AFER RS09095
gene id: 525909:AFER_RS09095
uniprot id: C7M127
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

525909:AFER RS02135
gene id: 525909:AFER_RS02135
uniprot id: C7M2Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

525909:AFER RS02770
gene id: 525909:AFER_RS02770
uniprot id: C7M3B0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

525909:AFER RS00690
gene id: 525909:AFER_RS00690
uniprot id: C7M206
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

525909:AFER RS11075
gene id: 525909:AFER_RS11075
uniprot id: C7LZN7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

525909:AFER RS03445
gene id: 525909:AFER_RS03445
uniprot id: C7LY15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

525909:AFER RS08090
gene id: 525909:AFER_RS08090
uniprot id: C7M0H5
names: Similarity
messages: Belongs to the thioredoxin family.

525909:AFER RS09180
gene id: 525909:AFER_RS09180
uniprot id: C7M144
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

525909:AFER RS05670
gene id: 525909:AFER_RS05670
uniprot id: C7LZ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

525909:AFER RS11380
gene id: 525909:AFER_RS11380
uniprot id: C7M2E6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS02890
gene id: 525909:AFER_RS02890
uniprot id: C7M3C7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

525909:AFER RS05140
gene id: 525909:AFER_RS05140
uniprot id: C7LYY3
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS08810
gene id: 525909:AFER_RS08810
uniprot id: C7M0V9
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

525909:AFER RS06355
gene id: 525909:AFER_RS06355
uniprot id: C7LZK7
names: Similarity
messages: Belongs to the pirin family.

525909:AFER RS04540
gene id: 525909:AFER_RS04540
uniprot id: C7LYL7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

525909:AFER RS05655
gene id: 525909:AFER_RS05655
uniprot id: C7LZ79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

525909:AFER RS08260
gene id: 525909:AFER_RS08260
uniprot id: C7M0K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

525909:AFER RS09430
gene id: 525909:AFER_RS09430
uniprot id: C7M192
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

525909:AFER RS06200
gene id: 525909:AFER_RS06200
uniprot id: C7LZH9
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS07190
gene id: 525909:AFER_RS07190
uniprot id: C7M010
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

525909:AFER RS10150
gene id: 525909:AFER_RS10150
uniprot id: C7M1W7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

525909:AFER RS01260
gene id: 525909:AFER_RS01260
uniprot id: C7M2G8
names: Similarity
messages: Belongs to the glutamine synthetase family.

525909:AFER RS01925
gene id: 525909:AFER_RS01925
uniprot id: C7M2U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

525909:AFER RS01650
gene id: 525909:AFER_RS01650
uniprot id: C7M2P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

525909:AFER RS10750
gene id: 525909:AFER_RS10750
uniprot id: C7M302
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

525909:AFER RS00420
gene id: 525909:AFER_RS00420
uniprot id: C7M1K7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

525909:AFER RS02285
gene id: 525909:AFER_RS02285
uniprot id: C7M318
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

525909:AFER RS02360
gene id: 525909:AFER_RS02360
uniprot id: C7M333
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

525909:AFER RS07020
gene id: 525909:AFER_RS07020
uniprot id: C7LZY1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

525909:AFER RS09255
gene id: 525909:AFER_RS09255
uniprot id: C7M158
names: Similarity
messages: Belongs to the FBPase class 2 family.

525909:AFER RS10250
gene id: 525909:AFER_RS10250
uniprot id: C7M1Y6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

525909:AFER RS01895
gene id: 525909:AFER_RS01895
uniprot id: C7M2U3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

525909:AFER RS01160
gene id: 525909:AFER_RS01160
uniprot id: C7M2F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

525909:AFER RS09555
gene id: 525909:AFER_RS09555
uniprot id: C7M1B6
names: Function
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

525909:AFER RS08275
gene id: 525909:AFER_RS08275
uniprot id: C7M0L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

525909:AFER RS09130
gene id: 525909:AFER_RS09130
uniprot id: C7M134
names: Similarity
messages: Belongs to the phosphohexose mutase family.

525909:AFER RS07960
gene id: 525909:AFER_RS07960
uniprot id: C7M0F3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

525909:AFER RS10115
gene id: 525909:AFER_RS10115
uniprot id: C7M1W0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

525909:AFER RS07955
gene id: 525909:AFER_RS07955
uniprot id: C7M0F2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

525909:AFER RS00175
gene id: 525909:AFER_RS00175
uniprot id: C7M1G1
names: Similarity
messages: Belongs to the peptidase S33 family.

525909:AFER RS04520
gene id: 525909:AFER_RS04520
uniprot id: C7LYL3
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

525909:AFER RS08805
gene id: 525909:AFER_RS08805
uniprot id: C7M0V8
names: Similarity
messages: Belongs to the CarA family.

525909:AFER RS00635
gene id: 525909:AFER_RS00635
uniprot id: C7M1Z5
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

525909:AFER RS02365
gene id: 525909:AFER_RS02365
uniprot id: C7M334
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

525909:AFER RS04085
gene id: 525909:AFER_RS04085
uniprot id: C7LYD3
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS01930
gene id: 525909:AFER_RS01930
uniprot id: C7M2V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

525909:AFER RS05665
gene id: 525909:AFER_RS05665
uniprot id: C7LZ81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

525909:AFER RS07800
gene id: 525909:AFER_RS07800
uniprot id: C7M0C3
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

525909:AFER RS08795
gene id: 525909:AFER_RS08795
uniprot id: C7M0V6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS06870
gene id: 525909:AFER_RS06870
uniprot id: C7LZV3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

525909:AFER RS05095
gene id: 525909:AFER_RS05095
uniprot id: C7LYX3
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS08800
gene id: 525909:AFER_RS08800
uniprot id: C7M0V7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS03675
gene id: 525909:AFER_RS03675
uniprot id: C7LY56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

525909:AFER RS01645
gene id: 525909:AFER_RS01645
uniprot id: C7M2P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

525909:AFER RS08815
gene id: 525909:AFER_RS08815
uniprot id: C7M0W0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

525909:AFER RS09035
gene id: 525909:AFER_RS09035
uniprot id: C7M107
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

525909:AFER RS09285
gene id: 525909:AFER_RS09285
uniprot id: C7M164
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

525909:AFER RS10170
gene id: 525909:AFER_RS10170
uniprot id: C7M1X1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

525909:AFER RS08055
gene id: 525909:AFER_RS08055
uniprot id: C7M0G8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

525909:AFER RS02240
gene id: 525909:AFER_RS02240
uniprot id: C7M309
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

525909:AFER RS09440
gene id: 525909:AFER_RS09440
uniprot id: C7M194
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

525909:AFER RS10950
gene id: 525909:AFER_RS10950
uniprot id: C7LYT6
names: Similarity
messages: Belongs to the PspA/IM30 family.

525909:AFER RS02110
gene id: 525909:AFER_RS02110
uniprot id: C7M2Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

525909:AFER RS04260
gene id: 525909:AFER_RS04260
uniprot id: C7LYG3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

525909:AFER RS07045
gene id: 525909:AFER_RS07045
uniprot id: C7LZY6
names: Similarity
messages: Belongs to the UPF0145 family.

525909:AFER RS10675
gene id: 525909:AFER_RS10675
uniprot id: C7M221
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

525909:AFER RS11345
gene id: 525909:AFER_RS11345
uniprot id: C7M1W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

525909:AFER RS10670
gene id: 525909:AFER_RS10670
uniprot id: C7M220
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

525909:AFER RS06270
gene id: 525909:AFER_RS06270
uniprot id: C7LZJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

525909:AFER RS04685
gene id: 525909:AFER_RS04685
uniprot id: C7LYP6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

525909:AFER RS10270
gene id: 525909:AFER_RS10270
uniprot id: C7M298
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

525909:AFER RS02050
gene id: 525909:AFER_RS02050
uniprot id: C7M2X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

525909:AFER RS06535
gene id: 525909:AFER_RS06535
uniprot id: C7LZP2
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS01660
gene id: 525909:AFER_RS01660
uniprot id: C7M2P6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

525909:AFER RS10300
gene id: 525909:AFER_RS10300
uniprot id: C7M2A4
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS09105
gene id: 525909:AFER_RS09105
uniprot id: C7M129
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

525909:AFER RS12220
gene id: 525909:AFER_RS12220
uniprot id: C7M331
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

525909:AFER RS07290
gene id: 525909:AFER_RS07290
uniprot id: C7M026
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

525909:AFER RS03570
gene id: 525909:AFER_RS03570
uniprot id: C7LY35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

525909:AFER RS08740
gene id: 525909:AFER_RS08740
uniprot id: C7M0U5
names: Similarity
messages: Belongs to the Fmt family.

525909:AFER RS07755
gene id: 525909:AFER_RS07755
uniprot id: C7M0B4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

525909:AFER RS06095
gene id: 525909:AFER_RS06095
uniprot id: C7LZF9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

525909:AFER RS02115
gene id: 525909:AFER_RS02115
uniprot id: C7M2Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

525909:AFER RS05180
gene id: 525909:AFER_RS05180
uniprot id: C7LYZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

525909:AFER RS05570
gene id: 525909:AFER_RS05570
uniprot id: C7LZ61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

525909:AFER RS10345
gene id: 525909:AFER_RS10345
uniprot id: C7M2B1
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS00215
gene id: 525909:AFER_RS00215
uniprot id: C7M1G8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

525909:AFER RS04080
gene id: 525909:AFER_RS04080
uniprot id: C7LYD2
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

525909:AFER RS07770
gene id: 525909:AFER_RS07770
uniprot id: C7M0B7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

525909:AFER RS04475
gene id: 525909:AFER_RS04475
uniprot id: C7LYK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

525909:AFER RS01315
gene id: 525909:AFER_RS01315
uniprot id: C7M2H9
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS02870
gene id: 525909:AFER_RS02870
uniprot id: C7M3C3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

525909:AFER RS08770
gene id: 525909:AFER_RS08770
uniprot id: C7M0V1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS08495
gene id: 525909:AFER_RS08495
uniprot id: C7M0P7
names: Similarity
messages: Belongs to the peptidase S51 family.

525909:AFER RS01695
gene id: 525909:AFER_RS01695
uniprot id: C7M2Q2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

525909:AFER RS03230
gene id: 525909:AFER_RS03230
uniprot id: C7LXX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

525909:AFER RS03225
gene id: 525909:AFER_RS03225
uniprot id: C7LXX4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS08865
gene id: 525909:AFER_RS08865
uniprot id: C7M0X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

525909:AFER RS03020
gene id: 525909:AFER_RS03020
uniprot id: C7LXT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

525909:AFER RS02925
gene id: 525909:AFER_RS02925
uniprot id: C7M3D3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

525909:AFER RS09355
gene id: 525909:AFER_RS09355
uniprot id: C7M178
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

525909:AFER RS01790
gene id: 525909:AFER_RS01790
uniprot id: C7M2S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

525909:AFER RS02945
gene id: 525909:AFER_RS02945
uniprot id: C7M3D7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

525909:AFER RS04695
gene id: 525909:AFER_RS04695
uniprot id: C7LYP8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

525909:AFER RS01820
gene id: 525909:AFER_RS01820
uniprot id: C7M2S7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

525909:AFER RS07460
gene id: 525909:AFER_RS07460
uniprot id: C7M059
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

525909:AFER RS06950
gene id: 525909:AFER_RS06950
uniprot id: C7LZW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

525909:AFER RS05825
gene id: 525909:AFER_RS05825
uniprot id: C7LZB3
names: Similarity
messages: Belongs to the TlyA family.

525909:AFER RS05440
gene id: 525909:AFER_RS05440
uniprot id: C7LZ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

525909:AFER RS01945
gene id: 525909:AFER_RS01945
uniprot id: C7M2V3
names: Similarity
messages: Belongs to the UPF0234 family.

525909:AFER RS03315
gene id: 525909:AFER_RS03315
uniprot id: C7LXZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

525909:AFER RS06330
gene id: 525909:AFER_RS06330
uniprot id: C7LZK2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS02705
gene id: 525909:AFER_RS02705
uniprot id: C7M397
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

525909:AFER RS09365
gene id: 525909:AFER_RS09365
uniprot id: C7M180
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

525909:AFER RS04160
gene id: 525909:AFER_RS04160
uniprot id: C7LYE6
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

525909:AFER RS06235
gene id: 525909:AFER_RS06235
uniprot id: C7LZI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

525909:AFER RS08425
gene id: 525909:AFER_RS08425
uniprot id: C7M0N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

525909:AFER RS06695
gene id: 525909:AFER_RS06695
uniprot id: C7LZS3
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS07715
gene id: 525909:AFER_RS07715
uniprot id: C7M0A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

525909:AFER RS08610
gene id: 525909:AFER_RS08610
uniprot id: C7M0S0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

525909:AFER RS04565
gene id: 525909:AFER_RS04565
uniprot id: C7LYM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

525909:AFER RS10110
gene id: 525909:AFER_RS10110
uniprot id: C7M1V9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

525909:AFER RS04670
gene id: 525909:AFER_RS04670
uniprot id: C7LYP3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

525909:AFER RS08325
gene id: 525909:AFER_RS08325
uniprot id: C7M0M0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

525909:AFER RS03935
gene id: 525909:AFER_RS03935
uniprot id: C7LYA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

525909:AFER RS06505
gene id: 525909:AFER_RS06505
uniprot id: C7LZN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

525909:AFER RS07055
gene id: 525909:AFER_RS07055
uniprot id: C7LZY8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

525909:AFER RS01735
gene id: 525909:AFER_RS01735
uniprot id: C7M2R1
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

525909:AFER RS07805
gene id: 525909:AFER_RS07805
uniprot id: C7M0C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

525909:AFER RS02415
gene id: 525909:AFER_RS02415
uniprot id: C7M343
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

525909:AFER RS03690
gene id: 525909:AFER_RS03690
uniprot id: C7LY59
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

525909:AFER RS03605
gene id: 525909:AFER_RS03605
uniprot id: C7LY42
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

525909:AFER RS04920
gene id: 525909:AFER_RS04920
uniprot id: C7LYT7
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS04370
gene id: 525909:AFER_RS04370
uniprot id: C7LYI5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS06060
gene id: 525909:AFER_RS06060
uniprot id: C7LZF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

525909:AFER RS00035
gene id: 525909:AFER_RS00035
uniprot id: C7M121
names: Similarity
messages: Belongs to the GSP E family.

525909:AFER RS01015
gene id: 525909:AFER_RS01015
uniprot id: C7M270
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

525909:AFER RS02045
gene id: 525909:AFER_RS02045
uniprot id: C7M2W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

525909:AFER RS03970
gene id: 525909:AFER_RS03970
uniprot id: C7LYB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

525909:AFER RS10775
gene id: 525909:AFER_RS10775
uniprot id: C7M351
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

525909:AFER RS01275
gene id: 525909:AFER_RS01275
uniprot id: C7M2H1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS06345
gene id: 525909:AFER_RS06345
uniprot id: C7LZK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

525909:AFER RS00670
gene id: 525909:AFER_RS00670
uniprot id: C7M202
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

525909:AFER RS10160
gene id: 525909:AFER_RS10160
uniprot id: C7M1W9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

525909:AFER RS08015
gene id: 525909:AFER_RS08015
uniprot id: C7M0G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

525909:AFER RS11055
gene id: 525909:AFER_RS11055
uniprot id: C7LZL3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

525909:AFER RS11330
gene id: 525909:AFER_RS11330
uniprot id: C7M1S2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

525909:AFER RS04985
gene id: 525909:AFER_RS04985
uniprot id: C7LYV0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

525909:AFER RS00845
gene id: 525909:AFER_RS00845
uniprot id: C7M236
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

525909:AFER RS09855
gene id: 525909:AFER_RS09855
uniprot id: C7M1R4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

525909:AFER RS02465
gene id: 525909:AFER_RS02465
uniprot id: C7M354
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS04185
gene id: 525909:AFER_RS04185
uniprot id: C7LYE9
names: Similarity
messages: Belongs to the peptidase M13 family.

525909:AFER RS00115
gene id: 525909:AFER_RS00115
uniprot id: C7M1F0
names: Similarity
messages: Belongs to the histone deacetylase family.

525909:AFER RS00610
gene id: 525909:AFER_RS00610
uniprot id: C7M1Z0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

525909:AFER RS06835
gene id: 525909:AFER_RS06835
uniprot id: C7LZU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

525909:AFER RS04265
gene id: 525909:AFER_RS04265
uniprot id: C7LYG4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

525909:AFER RS04500
gene id: 525909:AFER_RS04500
uniprot id: C7LYK9
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS00695
gene id: 525909:AFER_RS00695
uniprot id: C7M207
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

525909:AFER RS07310
gene id: 525909:AFER_RS07310
uniprot id: C7M030
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

525909:AFER RS05275
gene id: 525909:AFER_RS05275
uniprot id: C7LZ09
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

525909:AFER RS01825
gene id: 525909:AFER_RS01825
uniprot id: C7M2S8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

525909:AFER RS05605
gene id: 525909:AFER_RS05605
uniprot id: C7LZ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

525909:AFER RS04875
gene id: 525909:AFER_RS04875
uniprot id: C7LYS8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

525909:AFER RS07945
gene id: 525909:AFER_RS07945
uniprot id: C7M0F0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

525909:AFER RS05005
gene id: 525909:AFER_RS05005
uniprot id: C7LYV4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

525909:AFER RS00700
gene id: 525909:AFER_RS00700
uniprot id: C7M208
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

525909:AFER RS02190
gene id: 525909:AFER_RS02190
uniprot id: C7M2Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

525909:AFER RS09450
gene id: 525909:AFER_RS09450
uniprot id: C7M196
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS02345
gene id: 525909:AFER_RS02345
uniprot id: C7M330
names: Similarity
messages: Belongs to the UPF0166 family.

525909:AFER RS07775
gene id: 525909:AFER_RS07775
uniprot id: C7M0B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

525909:AFER RS02665
gene id: 525909:AFER_RS02665
uniprot id: C7M389
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS07810
gene id: 525909:AFER_RS07810
uniprot id: C7M0C5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

525909:AFER RS09460
gene id: 525909:AFER_RS09460
uniprot id: C7M198
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

525909:AFER RS09720
gene id: 525909:AFER_RS09720
uniprot id: C7M1P4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

525909:AFER RS05915
gene id: 525909:AFER_RS05915
uniprot id: C7LZD0
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

525909:AFER RS02010
gene id: 525909:AFER_RS02010
uniprot id: C7M2W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

525909:AFER RS04480
gene id: 525909:AFER_RS04480
uniprot id: C7LYK5
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS02735
gene id: 525909:AFER_RS02735
uniprot id: C7M3A3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

525909:AFER RS01525
gene id: 525909:AFER_RS01525
uniprot id: C7M2L9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

525909:AFER RS07610
gene id: 525909:AFER_RS07610
uniprot id: C7M086
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

525909:AFER RS09970
gene id: 525909:AFER_RS09970
uniprot id: C7M1T5
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

525909:AFER RS01710
gene id: 525909:AFER_RS01710
uniprot id: C7M2Q5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS00335
gene id: 525909:AFER_RS00335
uniprot id: C7M1J1
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS10245
gene id: 525909:AFER_RS10245
uniprot id: C7M1Y5
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

525909:AFER RS06260
gene id: 525909:AFER_RS06260
uniprot id: C7LZJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

525909:AFER RS01410
gene id: 525909:AFER_RS01410
uniprot id: C7M2J8
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

525909:AFER RS06185
gene id: 525909:AFER_RS06185
uniprot id: C7LZH6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

525909:AFER RS00545
gene id: 525909:AFER_RS00545
uniprot id: C7M1M8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

525909:AFER RS09290
gene id: 525909:AFER_RS09290
uniprot id: C7M165
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

525909:AFER RS10125
gene id: 525909:AFER_RS10125
uniprot id: C7M1W2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

525909:AFER RS04220
gene id: 525909:AFER_RS04220
uniprot id: C7LYF6
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

525909:AFER RS02015
gene id: 525909:AFER_RS02015
uniprot id: C7M2W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

525909:AFER RS00005
gene id: 525909:AFER_RS00005
uniprot id: C7M114
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

525909:AFER RS08030
gene id: 525909:AFER_RS08030
uniprot id: C7M0G3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

525909:AFER RS11015
gene id: 525909:AFER_RS11015
uniprot id: C7LZ92
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS04205
gene id: 525909:AFER_RS04205
uniprot id: C7LYF3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

525909:AFER RS01530
gene id: 525909:AFER_RS01530
uniprot id: C7M2M0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS01770
gene id: 525909:AFER_RS01770
uniprot id: C7M2R8
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS02020
gene id: 525909:AFER_RS02020
uniprot id: C7M2W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

525909:AFER RS09115
gene id: 525909:AFER_RS09115
uniprot id: C7M131
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

525909:AFER RS02210
gene id: 525909:AFER_RS02210
uniprot id: C7M303
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

525909:AFER RS05790
gene id: 525909:AFER_RS05790
uniprot id: C7LZA6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

525909:AFER RS07075
gene id: 525909:AFER_RS07075
uniprot id: C7LZZ2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

525909:AFER RS10455
gene id: 525909:AFER_RS10455
uniprot id: C7M2D0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

525909:AFER RS02950
gene id: 525909:AFER_RS02950
uniprot id: C7M3D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

525909:AFER RS10325
gene id: 525909:AFER_RS10325
uniprot id: C7M2A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

525909:AFER RS05865
gene id: 525909:AFER_RS05865
uniprot id: C7LZC1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

525909:AFER RS10265
gene id: 525909:AFER_RS10265
uniprot id: C7M297
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

525909:AFER RS07830
gene id: 525909:AFER_RS07830
uniprot id: C7M0C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

525909:AFER RS09750
gene id: 525909:AFER_RS09750
uniprot id: C7M1Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm

525909:AFER RS09265
gene id: 525909:AFER_RS09265
uniprot id: C7M160
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

525909:AFER RS06540
gene id: 525909:AFER_RS06540
uniprot id: C7LZP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

525909:AFER RS09995
gene id: 525909:AFER_RS09995
uniprot id: C7M1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

525909:AFER RS04315
gene id: 525909:AFER_RS04315
uniprot id: C7LYH4
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS07745
gene id: 525909:AFER_RS07745
uniprot id: C7M0B2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

525909:AFER RS07620
gene id: 525909:AFER_RS07620
uniprot id: C7M088
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

525909:AFER RS10460
gene id: 525909:AFER_RS10460
uniprot id: C7M2D1
names: Similarity
messages: Belongs to the CutA family.

525909:AFER RS02215
gene id: 525909:AFER_RS02215
uniprot id: C7M304
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

525909:AFER RS02920
gene id: 525909:AFER_RS02920
uniprot id: C7M3D2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

525909:AFER RS05320
gene id: 525909:AFER_RS05320
uniprot id: C7LZ18
names: Similarity
messages: Belongs to the UPF0098 family.

525909:AFER RS03920
gene id: 525909:AFER_RS03920
uniprot id: C7LYA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

525909:AFER RS03975
gene id: 525909:AFER_RS03975
uniprot id: C7LYB2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

525909:AFER RS09390
gene id: 525909:AFER_RS09390
uniprot id: C7M184
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

525909:AFER RS05795
gene id: 525909:AFER_RS05795
uniprot id: C7LZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

525909:AFER RS06275
gene id: 525909:AFER_RS06275
uniprot id: C7LZJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

525909:AFER RS09050
gene id: 525909:AFER_RS09050
uniprot id: C7M109
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

525909:AFER RS07920
gene id: 525909:AFER_RS07920
uniprot id: C7M0E5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

525909:AFER RS10515
gene id: 525909:AFER_RS10515
uniprot id: C7M2E1
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS06700
gene id: 525909:AFER_RS06700
uniprot id: C7LZS4
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

525909:AFER RS02220
gene id: 525909:AFER_RS02220
uniprot id: C7M305
names: Similarity
messages: Belongs to the phosphohexose mutase family.

525909:AFER RS06500
gene id: 525909:AFER_RS06500
uniprot id: C7LZN5
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

525909:AFER RS05735
gene id: 525909:AFER_RS05735
uniprot id: C7LZ95
names: Similarity
messages: Belongs to the GcvT family.

525909:AFER RS03735
gene id: 525909:AFER_RS03735
uniprot id: C7LY68
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

525909:AFER RS06875
gene id: 525909:AFER_RS06875
uniprot id: C7LZV4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

525909:AFER RS04575
gene id: 525909:AFER_RS04575
uniprot id: C7LYM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

525909:AFER RS08675
gene id: 525909:AFER_RS08675
uniprot id: C7M0T2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

525909:AFER RS10085
gene id: 525909:AFER_RS10085
uniprot id: C7M1V4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

525909:AFER RS12265
gene id: 525909:AFER_RS12265
uniprot id: C7LY05
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

525909:AFER RS01050
gene id: 525909:AFER_RS01050
uniprot id: C7M277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

525909:AFER RS03565
gene id: 525909:AFER_RS03565
uniprot id: C7LY34
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

525909:AFER RS01675
gene id: 525909:AFER_RS01675
uniprot id: C7M2P9
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS10565
gene id: 525909:AFER_RS10565
uniprot id: C7M2F0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

525909:AFER RS06575
gene id: 525909:AFER_RS06575
uniprot id: C7LZQ0
names: Similarity
messages: Belongs to the GSP E family.

525909:AFER RS04510
gene id: 525909:AFER_RS04510
uniprot id: C7LYL1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

525909:AFER RS02725
gene id: 525909:AFER_RS02725
uniprot id: C7M3A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

525909:AFER RS01535
gene id: 525909:AFER_RS01535
uniprot id: C7M2M1
names: Similarity
messages: Belongs to the UPF0145 family.

525909:AFER RS08075
gene id: 525909:AFER_RS08075
uniprot id: C7M0H2
names: Similarity
messages: Belongs to the Lgt family.

525909:AFER RS04355
gene id: 525909:AFER_RS04355
uniprot id: C7LYI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

525909:AFER RS02880
gene id: 525909:AFER_RS02880
uniprot id: C7M3C5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

525909:AFER RS06250
gene id: 525909:AFER_RS06250
uniprot id: C7LZI8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

525909:AFER RS09635
gene id: 525909:AFER_RS09635
uniprot id: C7M1C9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

525909:AFER RS05745
gene id: 525909:AFER_RS05745
uniprot id: C7LZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

525909:AFER RS05910
gene id: 525909:AFER_RS05910
uniprot id: C7LZC9
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

525909:AFER RS05585
gene id: 525909:AFER_RS05585
uniprot id: C7LZ64
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

525909:AFER RS00150
gene id: 525909:AFER_RS00150
uniprot id: C7M1F7
names: Similarity
messages: Belongs to the thioredoxin family.

525909:AFER RS05300
gene id: 525909:AFER_RS05300
uniprot id: C7LZ14
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

525909:AFER RS04390
gene id: 525909:AFER_RS04390
uniprot id: C7LYI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

525909:AFER RS05190
gene id: 525909:AFER_RS05190
uniprot id: C7LYZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

525909:AFER RS07405
gene id: 525909:AFER_RS07405
uniprot id: C7M050
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS08730
gene id: 525909:AFER_RS08730
uniprot id: C7M0U3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

525909:AFER RS03915
gene id: 525909:AFER_RS03915
uniprot id: C7LYA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

525909:AFER RS07750
gene id: 525909:AFER_RS07750
uniprot id: C7M0B3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

525909:AFER RS02160
gene id: 525909:AFER_RS02160
uniprot id: C7M2Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

525909:AFER RS10650
gene id: 525909:AFER_RS10650
uniprot id: C7M1M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

525909:AFER RS02690
gene id: 525909:AFER_RS02690
uniprot id: C7M394
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

525909:AFER RS05820
gene id: 525909:AFER_RS05820
uniprot id: C7LZB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS01305
gene id: 525909:AFER_RS01305
uniprot id: C7M2H7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

525909:AFER RS07905
gene id: 525909:AFER_RS07905
uniprot id: C7M0E3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

525909:AFER RS08870
gene id: 525909:AFER_RS08870
uniprot id: C7M0X2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

525909:AFER RS06420
gene id: 525909:AFER_RS06420
uniprot id: C7LZM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

525909:AFER RS03430
gene id: 525909:AFER_RS03430
uniprot id: C7LY12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

525909:AFER RS08715
gene id: 525909:AFER_RS08715
uniprot id: C7M0U0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

525909:AFER RS10195
gene id: 525909:AFER_RS10195
uniprot id: C7M1X6
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS04580
gene id: 525909:AFER_RS04580
uniprot id: C7LYM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

525909:AFER RS09820
gene id: 525909:AFER_RS09820
uniprot id: C7M1Q8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS03220
gene id: 525909:AFER_RS03220
uniprot id: C7LXX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

525909:AFER RS02200
gene id: 525909:AFER_RS02200
uniprot id: C7M301
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

525909:AFER RS03530
gene id: 525909:AFER_RS03530
uniprot id: C7LY29
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS02000
gene id: 525909:AFER_RS02000
uniprot id: C7M2W0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

525909:AFER RS06180
gene id: 525909:AFER_RS06180
uniprot id: C7LZH5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

525909:AFER RS05235
gene id: 525909:AFER_RS05235
uniprot id: C7LZ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

525909:AFER RS03740
gene id: 525909:AFER_RS03740
uniprot id: C7LY69
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

525909:AFER RS02005
gene id: 525909:AFER_RS02005
uniprot id: C7M2W1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

525909:AFER RS01520
gene id: 525909:AFER_RS01520
uniprot id: C7M2L8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

525909:AFER RS10865
gene id: 525909:AFER_RS10865
uniprot id: C7LY93
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

525909:AFER RS11880
gene id: 525909:AFER_RS11880
uniprot id: C7M219
names: Similarity
messages: Belongs to the MotB family.

525909:AFER RS03765
gene id: 525909:AFER_RS03765
uniprot id: C7LY74
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

525909:AFER RS10070
gene id: 525909:AFER_RS10070
uniprot id: C7M1V1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS10060
gene id: 525909:AFER_RS10060
uniprot id: C7M1U9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

525909:AFER RS10360
gene id: 525909:AFER_RS10360
uniprot id: C7M2B3
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS02255
gene id: 525909:AFER_RS02255
uniprot id: C7M312
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

525909:AFER RS06740
gene id: 525909:AFER_RS06740
uniprot id: C7LZT3
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS01555
gene id: 525909:AFER_RS01555
uniprot id: C7M2M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

525909:AFER RS00870
gene id: 525909:AFER_RS00870
uniprot id: C7M241
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

525909:AFER RS01350
gene id: 525909:AFER_RS01350
uniprot id: C7M2I6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

525909:AFER RS00580
gene id: 525909:AFER_RS00580
uniprot id: C7M1N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

525909:AFER RS08790
gene id: 525909:AFER_RS08790
uniprot id: C7M0V5
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

525909:AFER RS00740
gene id: 525909:AFER_RS00740
uniprot id: C7M216
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

525909:AFER RS02755
gene id: 525909:AFER_RS02755
uniprot id: C7M3A7
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

525909:AFER RS05625
gene id: 525909:AFER_RS05625
uniprot id: C7LZ73
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS03575
gene id: 525909:AFER_RS03575
uniprot id: C7LY36
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS08710
gene id: 525909:AFER_RS08710
uniprot id: C7M0T9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

525909:AFER RS12795
gene id: 525909:AFER_RS12795
uniprot id: C7M0R3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

525909:AFER RS01755
gene id: 525909:AFER_RS01755
uniprot id: C7M2R5
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS06405
gene id: 525909:AFER_RS06405
uniprot id: C7LZL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

525909:AFER RS09410
gene id: 525909:AFER_RS09410
uniprot id: C7M188
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

525909:AFER RS05310
gene id: 525909:AFER_RS05310
uniprot id: C7LZ16
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS09525
gene id: 525909:AFER_RS09525
uniprot id: C7M1B0
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

525909:AFER RS04415
gene id: 525909:AFER_RS04415
uniprot id: C7LYJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

525909:AFER RS02065
gene id: 525909:AFER_RS02065
uniprot id: C7M2X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

525909:AFER RS02475
gene id: 525909:AFER_RS02475
uniprot id: C7M356
names: Similarity
messages: Belongs to the peptidase C56 family.

525909:AFER RS10130
gene id: 525909:AFER_RS10130
uniprot id: C7M1W3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

525909:AFER RS05535
gene id: 525909:AFER_RS05535
uniprot id: C7LZ56
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

525909:AFER RS02675
gene id: 525909:AFER_RS02675
uniprot id: C7M391
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

525909:AFER RS04705
gene id: 525909:AFER_RS04705
uniprot id: C7LYQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

525909:AFER RS07445
gene id: 525909:AFER_RS07445
uniprot id: C7M056
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

525909:AFER RS01920
gene id: 525909:AFER_RS01920
uniprot id: C7M2U8
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS02130
gene id: 525909:AFER_RS02130
uniprot id: C7M2Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

525909:AFER RS06400
gene id: 525909:AFER_RS06400
uniprot id: C7LZL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

525909:AFER RS06240
gene id: 525909:AFER_RS06240
uniprot id: C7LZI7
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS12435
gene id: 525909:AFER_RS12435
uniprot id: C7M0X7
names: Similarity
messages: Belongs to the peptidase A24 family.

525909:AFER RS03660
gene id: 525909:AFER_RS03660
uniprot id: C7LY53
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS08020
gene id: 525909:AFER_RS08020
uniprot id: C7M0G1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

525909:AFER RS07930
gene id: 525909:AFER_RS07930
uniprot id: C7M0E7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

525909:AFER RS06110
gene id: 525909:AFER_RS06110
uniprot id: C7LZG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

525909:AFER RS07275
gene id: 525909:AFER_RS07275
uniprot id: C7M024
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

525909:AFER RS09865
gene id: 525909:AFER_RS09865
uniprot id: C7M1R6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

525909:AFER RS09345
gene id: 525909:AFER_RS09345
uniprot id: C7M176
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

525909:AFER RS09370
gene id: 525909:AFER_RS09370
uniprot id: C7M181
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

525909:AFER RS09465
gene id: 525909:AFER_RS09465
uniprot id: C7M199
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

525909:AFER RS00645
gene id: 525909:AFER_RS00645
uniprot id: C7M1Z7
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

525909:AFER RS00705
gene id: 525909:AFER_RS00705
uniprot id: C7M209
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

525909:AFER RS03340
gene id: 525909:AFER_RS03340
uniprot id: C7LXZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

525909:AFER RS00800
gene id: 525909:AFER_RS00800
uniprot id: C7M227
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

525909:AFER RS01205
gene id: 525909:AFER_RS01205
uniprot id: C7M2F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

525909:AFER RS02370
gene id: 525909:AFER_RS02370
uniprot id: C7M335
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

525909:AFER RS04910
gene id: 525909:AFER_RS04910
uniprot id: C7LYT5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS10730
gene id: 525909:AFER_RS10730
uniprot id: C7M2M3
names: Similarity
messages: Belongs to the peptidase C40 family.

525909:AFER RS01580
gene id: 525909:AFER_RS01580
uniprot id: C7M2N0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

525909:AFER RS02140
gene id: 525909:AFER_RS02140
uniprot id: C7M2Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

525909:AFER RS04025
gene id: 525909:AFER_RS04025
uniprot id: C7LYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

525909:AFER RS03300
gene id: 525909:AFER_RS03300
uniprot id: C7LXY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

525909:AFER RS05845
gene id: 525909:AFER_RS05845
uniprot id: C7LZB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

525909:AFER RS05685
gene id: 525909:AFER_RS05685
uniprot id: C7LZ85
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

525909:AFER RS10740
gene id: 525909:AFER_RS10740
uniprot id: C7M2R3
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

525909:AFER RS05410
gene id: 525909:AFER_RS05410
uniprot id: C7LZ36
names: Similarity
messages: Belongs to the ABC transporter superfamily.

525909:AFER RS01915
gene id: 525909:AFER_RS01915
uniprot id: C7M2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

525909:AFER RS03280
gene id: 525909:AFER_RS03280
uniprot id: C7LXY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

525909:AFER RS06335
gene id: 525909:AFER_RS06335
uniprot id: C7LZK3
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Monomer.

525909:AFER RS01890
gene id: 525909:AFER_RS01890
uniprot id: C7M2U2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

525909:AFER RS01505
gene id: 525909:AFER_RS01505
uniprot id: C7M2L5
names: Similarity
messages: Belongs to the universal stress protein A family.

525909:AFER RS02250
gene id: 525909:AFER_RS02250
uniprot id: C7M311
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

525909:AFER RS09250
gene id: 525909:AFER_RS09250
uniprot id: C7M157
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

525909:AFER RS02090
gene id: 525909:AFER_RS02090
uniprot id: C7M2X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

525909:AFER RS00980
gene id: 525909:AFER_RS00980
uniprot id: C7M264
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS01290
gene id: 525909:AFER_RS01290
uniprot id: C7M2H4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

525909:AFER RS02125
gene id: 525909:AFER_RS02125
uniprot id: C7M2Y5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

525909:AFER RS08585
gene id: 525909:AFER_RS08585
uniprot id: C7M0R5
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

525909:AFER RS05325
gene id: 525909:AFER_RS05325
uniprot id: C7LZ19
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS04515
gene id: 525909:AFER_RS04515
uniprot id: C7LYL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

525909:AFER RS01180
gene id: 525909:AFER_RS01180
uniprot id: C7M2F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

525909:AFER RS01885
gene id: 525909:AFER_RS01885
uniprot id: C7M2U1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

525909:AFER RS07560
gene id: 525909:AFER_RS07560
uniprot id: C7M077
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

525909:AFER RS08410
gene id: 525909:AFER_RS08410
uniprot id: C7M0N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

525909:AFER RS09535
gene id: 525909:AFER_RS09535
uniprot id: C7M1B2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

525909:AFER RS08690
gene id: 525909:AFER_RS08690
uniprot id: C7M0T5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

525909:AFER RS07250
gene id: 525909:AFER_RS07250
uniprot id: C7M020
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

525909:AFER RS06365
gene id: 525909:AFER_RS06365
uniprot id: C7LZK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

525909:AFER RS07455
gene id: 525909:AFER_RS07455
uniprot id: C7M058
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

525909:AFER RS03250
gene id: 525909:AFER_RS03250
uniprot id: C7LXX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

525909:AFER RS00145
gene id: 525909:AFER_RS00145
uniprot id: C7M1F6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

525909:AFER RS06360
gene id: 525909:AFER_RS06360
uniprot id: C7LZK8
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

525909:AFER RS06985
gene id: 525909:AFER_RS06985
uniprot id: C7LZX4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

525909:AFER RS04750
gene id: 525909:AFER_RS04750
uniprot id: C7LYQ9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

525909:AFER RS00185
gene id: 525909:AFER_RS00185
uniprot id: C7M1G3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

525909:AFER RS07300
gene id: 525909:AFER_RS07300
uniprot id: C7M028
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

525909:AFER RS05415
gene id: 525909:AFER_RS05415
uniprot id: C7LZ37
names: Similarity
messages: Belongs to the ABC transporter superfamily.

525909:AFER RS00960
gene id: 525909:AFER_RS00960
uniprot id: C7M259
names: Similarity
messages: Belongs to the cytochrome b560 family.

525909:AFER RS09930
gene id: 525909:AFER_RS09930
uniprot id: C7M1S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

525909:AFER RS05815
gene id: 525909:AFER_RS05815
uniprot id: C7LZB1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

525909:AFER RS01135
gene id: 525909:AFER_RS01135
uniprot id: C7M292
names: Similarity
messages: Belongs to the peptidase S51 family.

525909:AFER RS00585
gene id: 525909:AFER_RS00585
uniprot id: C7M1N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

525909:AFER RS04870
gene id: 525909:AFER_RS04870
uniprot id: C7LYS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

525909:AFER RS10315
gene id: 525909:AFER_RS10315
uniprot id: C7M2A7
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

525909:AFER RS00535
gene id: 525909:AFER_RS00535
uniprot id: C7M1M6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

525909:AFER RS02170
gene id: 525909:AFER_RS02170
uniprot id: C7M2Z4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

525909:AFER RS03380
gene id: 525909:AFER_RS03380
uniprot id: C7LY04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

525909:AFER RS00795
gene id: 525909:AFER_RS00795
uniprot id: C7M226
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

525909:AFER RS04345
gene id: 525909:AFER_RS04345
uniprot id: C7LYI0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

525909:AFER RS04680
gene id: 525909:AFER_RS04680
uniprot id: C7LYP5
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

525909:AFER RS06415
gene id: 525909:AFER_RS06415
uniprot id: C7LZM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

525909:AFER RS09475
gene id: 525909:AFER_RS09475
uniprot id: C7M1A1
names: Similarity
messages: Belongs to the citrate synthase family.

525909:AFER RS07005
gene id: 525909:AFER_RS07005
uniprot id: C7LZX8
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

525909:AFER RS02885
gene id: 525909:AFER_RS02885
uniprot id: C7M3C6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

525909:AFER RS03295
gene id: 525909:AFER_RS03295
uniprot id: C7LXY7
names: Similarity
messages: Belongs to the ribF family.

525909:AFER RS08245
gene id: 525909:AFER_RS08245
uniprot id: C7M0K4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

525909:AFER RS02560
gene id: 525909:AFER_RS02560
uniprot id: C7M371
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS12640
gene id: 525909:AFER_RS12640
uniprot id: C7LY38
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

525909:AFER RS04845
gene id: 525909:AFER_RS04845
uniprot id: C7LYS2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

525909:AFER RS00805
gene id: 525909:AFER_RS00805
uniprot id: C7M228
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

525909:AFER RS02670
gene id: 525909:AFER_RS02670
uniprot id: C7M390
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS03695
gene id: 525909:AFER_RS03695
uniprot id: C7LY60
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

525909:AFER RS06155
gene id: 525909:AFER_RS06155
uniprot id: C7LZH1
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

525909:AFER RS03305
gene id: 525909:AFER_RS03305
uniprot id: C7LXY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

525909:AFER RS09110
gene id: 525909:AFER_RS09110
uniprot id: C7M130
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

525909:AFER RS03780
gene id: 525909:AFER_RS03780
uniprot id: C7LY77
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

525909:AFER RS02180
gene id: 525909:AFER_RS02180
uniprot id: C7M2Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

525909:AFER RS02165
gene id: 525909:AFER_RS02165
uniprot id: C7M2Z3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

525909:AFER RS05600
gene id: 525909:AFER_RS05600
uniprot id: C7LZ68
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Belongs to the HIBADH-related family.

525909:AFER RS06975
gene id: 525909:AFER_RS06975
uniprot id: C7LZX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

525909:AFER RS07475
gene id: 525909:AFER_RS07475
uniprot id: C7M062
names: Similarity
messages: Belongs to the universal stress protein A family.

525909:AFER RS07765
gene id: 525909:AFER_RS07765
uniprot id: C7M0B6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

525909:AFER RS10140
gene id: 525909:AFER_RS10140
uniprot id: C7M1W5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

525909:AFER RS00555
gene id: 525909:AFER_RS00555
uniprot id: C7M1N0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

525909:AFER RS07115
gene id: 525909:AFER_RS07115
uniprot id: C7M000
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

525909:AFER RS00975
gene id: 525909:AFER_RS00975
uniprot id: C7M263
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

525909:AFER RS06075
gene id: 525909:AFER_RS06075
uniprot id: C7LZF5
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS08040
gene id: 525909:AFER_RS08040
uniprot id: C7M0G5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

525909:AFER RS04385
gene id: 525909:AFER_RS04385
uniprot id: C7LYI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

525909:AFER RS03350
gene id: 525909:AFER_RS03350
uniprot id: C7LXZ8
names: Similarity
messages: Belongs to the CinA family.

525909:AFER RS02460
gene id: 525909:AFER_RS02460
uniprot id: C7M353
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS02995
gene id: 525909:AFER_RS02995
uniprot id: C7LXT2
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS08395
gene id: 525909:AFER_RS08395
uniprot id: C7M0N2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

525909:AFER RS00010
gene id: 525909:AFER_RS00010
uniprot id: C7M115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

525909:AFER RS04070
gene id: 525909:AFER_RS04070
uniprot id: C7LYD0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

525909:AFER RS12270
gene id: 525909:AFER_RS12270
uniprot id: C7LY06
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

525909:AFER RS02080
gene id: 525909:AFER_RS02080
uniprot id: C7M2X6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

525909:AFER RS04900
gene id: 525909:AFER_RS04900
uniprot id: C7LYT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

525909:AFER RS09350
gene id: 525909:AFER_RS09350
uniprot id: C7M177
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS03625
gene id: 525909:AFER_RS03625
uniprot id: C7LY46
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

525909:AFER RS02275
gene id: 525909:AFER_RS02275
uniprot id: C7M316
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

525909:AFER RS04395
gene id: 525909:AFER_RS04395
uniprot id: C7LYJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

525909:AFER RS10520
gene id: 525909:AFER_RS10520
uniprot id: C7M2E2
names: Similarity
messages: Belongs to the ParB family.

525909:AFER RS06130
gene id: 525909:AFER_RS06130
uniprot id: C7LZG6
names: Similarity
messages: Belongs to the peptidase C40 family.

525909:AFER RS09710
gene id: 525909:AFER_RS09710
uniprot id: C7M1P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

525909:AFER RS03925
gene id: 525909:AFER_RS03925
uniprot id: C7LYA3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

525909:AFER RS05430
gene id: 525909:AFER_RS05430
uniprot id: C7LZ39
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS06440
gene id: 525909:AFER_RS06440
uniprot id: C7LZM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

525909:AFER RS02850
gene id: 525909:AFER_RS02850
uniprot id: C7M3B9
names: Similarity
messages: Belongs to the peptidase S1C family.

525909:AFER RS00725
gene id: 525909:AFER_RS00725
uniprot id: C7M213
names: Similarity
messages: Belongs to the peptidase C40 family.
messages: Belongs to the transglycosylase Slt family.

525909:AFER RS00320
gene id: 525909:AFER_RS00320
uniprot id: C7M1I7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

525909:AFER RS00210
gene id: 525909:AFER_RS00210
uniprot id: C7M1G7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

525909:AFER RS08600
gene id: 525909:AFER_RS08600
uniprot id: C7M0R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

525909:AFER RS00900
gene id: 525909:AFER_RS00900
uniprot id: C7M247
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

525909:AFER RS05580
gene id: 525909:AFER_RS05580
uniprot id: C7LZ63
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

525909:AFER RS06255
gene id: 525909:AFER_RS06255
uniprot id: C7LZI9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

525909:AFER RS08025
gene id: 525909:AFER_RS08025
uniprot id: C7M0G2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS10145
gene id: 525909:AFER_RS10145
uniprot id: C7M1W6
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

525909:AFER RS01980
gene id: 525909:AFER_RS01980
uniprot id: C7M2V7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

525909:AFER RS02605
gene id: 525909:AFER_RS02605
uniprot id: C7M381
names: Subcellular Location Annotation
messages: Cytoplasm

525909:AFER RS08775
gene id: 525909:AFER_RS08775
uniprot id: C7M0V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

525909:AFER RS01085
gene id: 525909:AFER_RS01085
uniprot id: C7M282
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

525909:AFER RS08685
gene id: 525909:AFER_RS08685
uniprot id: C7M0T4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

525909:AFER RS09140
gene id: 525909:AFER_RS09140
uniprot id: C7M136
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

525909:AFER RS03595
gene id: 525909:AFER_RS03595
uniprot id: C7LY40
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

525909:AFER RS00625
gene id: 525909:AFER_RS00625
uniprot id: C7M1Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family. CsoSCA subfamily.
messages: Carboxysome

525909:AFER RS01900
gene id: 525909:AFER_RS01900
uniprot id: C7M2U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

525909:AFER RS06150
gene id: 525909:AFER_RS06150
uniprot id: C7LZH0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

525909:AFER RS02105
gene id: 525909:AFER_RS02105
uniprot id: C7M2Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

525909:AFER RS03360
gene id: 525909:AFER_RS03360
uniprot id: C7LY00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

525909:AFER RS09335
gene id: 525909:AFER_RS09335
uniprot id: C7M174
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

525909:AFER RS00225
gene id: 525909:AFER_RS00225
uniprot id: C7M1H0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS02495
gene id: 525909:AFER_RS02495
uniprot id: C7M359
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

525909:AFER RS00530
gene id: 525909:AFER_RS00530
uniprot id: C7M1M5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

525909:AFER RS00025
gene id: 525909:AFER_RS00025
uniprot id: C7M119
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

525909:AFER RS11050
gene id: 525909:AFER_RS11050
uniprot id: C7LZL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

525909:AFER RS04130
gene id: 525909:AFER_RS04130
uniprot id: C7LYE0
names: Similarity
messages: Belongs to the CobH/CbiC family.

525909:AFER RS09950
gene id: 525909:AFER_RS09950
uniprot id: C7M1T2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

525909:AFER RS09550
gene id: 525909:AFER_RS09550
uniprot id: C7M1B5
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

525909:AFER RS08745
gene id: 525909:AFER_RS08745
uniprot id: C7M0U6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

525909:AFER RS09360
gene id: 525909:AFER_RS09360
uniprot id: C7M179
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

525909:AFER RS03290
gene id: 525909:AFER_RS03290
uniprot id: C7LXY6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

525909:AFER RS07815
gene id: 525909:AFER_RS07815
uniprot id: C7M0C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

525909:AFER RS05800
gene id: 525909:AFER_RS05800
uniprot id: C7LZA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

525909:AFER RS04280
gene id: 525909:AFER_RS04280
uniprot id: C7LYG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

525909:AFER RS02055
gene id: 525909:AFER_RS02055
uniprot id: C7M2X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

525909:AFER RS00750
gene id: 525909:AFER_RS00750
uniprot id: C7M218
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

525909:AFER RS02565
gene id: 525909:AFER_RS02565
uniprot id: C7M372
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

525909:AFER RS09185
gene id: 525909:AFER_RS09185
uniprot id: C7M145
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

525909:AFER RS06370
gene id: 525909:AFER_RS06370
uniprot id: C7LZL0
names: Similarity
messages: Belongs to the YggT family.

525909:AFER RS02935
gene id: 525909:AFER_RS02935
uniprot id: C7M3D5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

525909:AFER RS05690
gene id: 525909:AFER_RS05690
uniprot id: C7LZ86
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

525909:AFER RS08500
gene id: 525909:AFER_RS08500
uniprot id: C7M0P8
names: Similarity
messages: Belongs to the group II decarboxylase family.

525909:AFER RS07360
gene id: 525909:AFER_RS07360
uniprot id: C7M040
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

525909:AFER RS08145
gene id: 525909:AFER_RS08145
uniprot id: C7M0I5
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS08670
gene id: 525909:AFER_RS08670
uniprot id: C7M0T1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

525909:AFER RS03375
gene id: 525909:AFER_RS03375
uniprot id: C7LY03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS03705
gene id: 525909:AFER_RS03705
uniprot id: C7LY62
names: Similarity
messages: Belongs to the peptidase M24B family.

525909:AFER RS03440
gene id: 525909:AFER_RS03440
uniprot id: C7LY14
names: Similarity
messages: Belongs to the peptidase S24 family.

525909:AFER RS02185
gene id: 525909:AFER_RS02185
uniprot id: C7M2Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

525909:AFER RS06815
gene id: 525909:AFER_RS06815
uniprot id: C7LZU3
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS00375
gene id: 525909:AFER_RS00375
uniprot id: C7M1J8
names: Similarity
messages: Belongs to the group II decarboxylase family.

525909:AFER RS10555
gene id: 525909:AFER_RS10555
uniprot id: C7M2E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

525909:AFER RS00615
gene id: 525909:AFER_RS00615
uniprot id: C7M1Z1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

525909:AFER RS06795
gene id: 525909:AFER_RS06795
uniprot id: C7LZU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

525909:AFER RS09315
gene id: 525909:AFER_RS09315
uniprot id: C7M170
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS08665
gene id: 525909:AFER_RS08665
uniprot id: C7M0T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

525909:AFER RS02595
gene id: 525909:AFER_RS02595
uniprot id: C7M379
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS03775
gene id: 525909:AFER_RS03775
uniprot id: C7LY76
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

525909:AFER RS04895
gene id: 525909:AFER_RS04895
uniprot id: C7LYT2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

525909:AFER RS01300
gene id: 525909:AFER_RS01300
uniprot id: C7M2H6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

525909:AFER RS10870
gene id: 525909:AFER_RS10870
uniprot id: C7LYA0
names: Similarity
messages: Belongs to the CsoR family.

525909:AFER RS07940
gene id: 525909:AFER_RS07940
uniprot id: C7M0E9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

525909:AFER RS05080
gene id: 525909:AFER_RS05080
uniprot id: C7LYX0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

525909:AFER RS04135
gene id: 525909:AFER_RS04135
uniprot id: C7LYE1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

525909:AFER RS02145
gene id: 525909:AFER_RS02145
uniprot id: C7M2Y9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

525909:AFER RS02230
gene id: 525909:AFER_RS02230
uniprot id: C7M307
names: Subcellular Location Annotation
messages: Membrane

525909:AFER RS06280
gene id: 525909:AFER_RS06280
uniprot id: C7LZJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

525909:AFER RS04860
gene id: 525909:AFER_RS04860
uniprot id: C7LYS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.