521460:ATHE RS13925
gene id: 521460:ATHE_RS13925
uniprot id: B9MQF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

521460:ATHE RS10400
gene id: 521460:ATHE_RS10400
uniprot id: B9MLF8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

521460:ATHE RS03900
gene id: 521460:ATHE_RS03900
uniprot id: B9MQA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS05565
gene id: 521460:ATHE_RS05565
uniprot id: B9MRA9
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS02750
gene id: 521460:ATHE_RS02750
uniprot id: B9MPC0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

521460:ATHE RS09740
gene id: 521460:ATHE_RS09740
uniprot id: B9ML20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS05455
gene id: 521460:ATHE_RS05455
uniprot id: B9MR87
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

521460:ATHE RS10270
gene id: 521460:ATHE_RS10270
uniprot id: B9MLD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

521460:ATHE RS03160
gene id: 521460:ATHE_RS03160
uniprot id: B9MPJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS07440
gene id: 521460:ATHE_RS07440
uniprot id: B9MJT2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

521460:ATHE RS07045
gene id: 521460:ATHE_RS07045
uniprot id: B9MS57
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

521460:ATHE RS11055
gene id: 521460:ATHE_RS11055
uniprot id: B9MM50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

521460:ATHE RS08635
gene id: 521460:ATHE_RS08635
uniprot id: B9MKF3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

521460:ATHE RS09000
gene id: 521460:ATHE_RS09000
uniprot id: B9MKM5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

521460:ATHE RS09825
gene id: 521460:ATHE_RS09825
uniprot id: B9ML55
names: Similarity
messages: Belongs to the UPF0735 family.

521460:ATHE RS04890
gene id: 521460:ATHE_RS04890
uniprot id: B9MQX5
names: Similarity
messages: Belongs to the UPF0102 family.

521460:ATHE RS07675
gene id: 521460:ATHE_RS07675
uniprot id: B9MJX4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

521460:ATHE RS11525
gene id: 521460:ATHE_RS11525
uniprot id: B9MMQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

521460:ATHE RS09565
gene id: 521460:ATHE_RS09565
uniprot id: B9MKY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

521460:ATHE RS07120
gene id: 521460:ATHE_RS07120
uniprot id: B9MS72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

521460:ATHE RS04080
gene id: 521460:ATHE_RS04080
uniprot id: B9MQH6
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS05790
gene id: 521460:ATHE_RS05790
uniprot id: B9MRF5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

521460:ATHE RS11530
gene id: 521460:ATHE_RS11530
uniprot id: B9MMR0
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

521460:ATHE RS02480
gene id: 521460:ATHE_RS02480
uniprot id: B9MNU8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

521460:ATHE RS05775
gene id: 521460:ATHE_RS05775
uniprot id: B9MRF2
names: Similarity
messages: Belongs to the fabD family.

521460:ATHE RS03155
gene id: 521460:ATHE_RS03155
uniprot id: B9MPJ7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

521460:ATHE RS11715
gene id: 521460:ATHE_RS11715
uniprot id: B9MMU7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521460:ATHE RS09510
gene id: 521460:ATHE_RS09510
uniprot id: B9MKX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

521460:ATHE RS03170
gene id: 521460:ATHE_RS03170
uniprot id: B9MPK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

521460:ATHE RS00975
gene id: 521460:ATHE_RS00975
uniprot id: B9MMB8
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

521460:ATHE RS08740
gene id: 521460:ATHE_RS08740
uniprot id: B9MKH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

521460:ATHE RS02235
gene id: 521460:ATHE_RS02235
uniprot id: B9MNQ6
names: Similarity
messages: Belongs to the hemerythrin family.

521460:ATHE RS04020
gene id: 521460:ATHE_RS04020
uniprot id: B9MQG4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

521460:ATHE RS06305
gene id: 521460:ATHE_RS06305
uniprot id: B9MRQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

521460:ATHE RS12040
gene id: 521460:ATHE_RS12040
uniprot id: B9MNC9
names: Similarity
messages: Belongs to the FGGY kinase family.

521460:ATHE RS03920
gene id: 521460:ATHE_RS03920
uniprot id: B9MQA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

521460:ATHE RS01960
gene id: 521460:ATHE_RS01960
uniprot id: B9MN76
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

521460:ATHE RS12635
gene id: 521460:ATHE_RS12635
uniprot id: B9MP15
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

521460:ATHE RS02185
gene id: 521460:ATHE_RS02185
uniprot id: B9MNP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

521460:ATHE RS02985
gene id: 521460:ATHE_RS02985
uniprot id: B9MPG6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521460:ATHE RS08715
gene id: 521460:ATHE_RS08715
uniprot id: B9MKG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

521460:ATHE RS06980
gene id: 521460:ATHE_RS06980
uniprot id: B9MS43
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS06630
gene id: 521460:ATHE_RS06630
uniprot id: B9MRX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

521460:ATHE RS10540
gene id: 521460:ATHE_RS10540
uniprot id: B9MLV2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS03750
gene id: 521460:ATHE_RS03750
uniprot id: B9MQ77
names: Subcellular Location Annotation
messages: Cytoplasm

521460:ATHE RS07915
gene id: 521460:ATHE_RS07915
uniprot id: B9MK16
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS11060
gene id: 521460:ATHE_RS11060
uniprot id: B9MM51
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

521460:ATHE RS00900
gene id: 521460:ATHE_RS00900
uniprot id: B9MMA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

521460:ATHE RS13000
gene id: 521460:ATHE_RS13000
uniprot id: B9MP82
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

521460:ATHE RS03910
gene id: 521460:ATHE_RS03910
uniprot id: B9MQA4
names: Similarity
messages: Belongs to the UPF0749 family.

521460:ATHE RS02490
gene id: 521460:ATHE_RS02490
uniprot id: B9MNV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

521460:ATHE RS12660
gene id: 521460:ATHE_RS12660
uniprot id: B9MP20
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

521460:ATHE RS02310
gene id: 521460:ATHE_RS02310
uniprot id: B9MNS1
names: Similarity
messages: Belongs to the glycosyl hydrolase.

521460:ATHE RS00210
gene id: 521460:ATHE_RS00210
uniprot id: B9MLK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

521460:ATHE RS10815
gene id: 521460:ATHE_RS10815
uniprot id: B9MM05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

521460:ATHE RS06445
gene id: 521460:ATHE_RS06445
uniprot id: B9MRT5
names: Similarity
messages: Belongs to the TlyA family.

521460:ATHE RS10205
gene id: 521460:ATHE_RS10205
uniprot id: B9MLB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS09095
gene id: 521460:ATHE_RS09095
uniprot id: B9MKP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

521460:ATHE RS00420
gene id: 521460:ATHE_RS00420
uniprot id: B9MLN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS01230
gene id: 521460:ATHE_RS01230
uniprot id: B9MMG9
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS00730
gene id: 521460:ATHE_RS00730
uniprot id: B9MM70
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

521460:ATHE RS08200
gene id: 521460:ATHE_RS08200
uniprot id: B9MK75
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

521460:ATHE RS08655
gene id: 521460:ATHE_RS08655
uniprot id: B9MKF7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

521460:ATHE RS00980
gene id: 521460:ATHE_RS00980
uniprot id: B9MMB9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

521460:ATHE RS08925
gene id: 521460:ATHE_RS08925
uniprot id: B9MKL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

521460:ATHE RS00895
gene id: 521460:ATHE_RS00895
uniprot id: B9MMA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

521460:ATHE RS07490
gene id: 521460:ATHE_RS07490
uniprot id: B9MJU2
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

521460:ATHE RS08670
gene id: 521460:ATHE_RS08670
uniprot id: B9MKG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

521460:ATHE RS11720
gene id: 521460:ATHE_RS11720
uniprot id: B9MMU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS00535
gene id: 521460:ATHE_RS00535
uniprot id: B9MLQ9
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS09620
gene id: 521460:ATHE_RS09620
uniprot id: B9MKZ8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

521460:ATHE RS06370
gene id: 521460:ATHE_RS06370
uniprot id: B9MRS1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

521460:ATHE RS10910
gene id: 521460:ATHE_RS10910
uniprot id: B9MM24
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

521460:ATHE RS07375
gene id: 521460:ATHE_RS07375
uniprot id: B9MJR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

521460:ATHE RS11935
gene id: 521460:ATHE_RS11935
uniprot id: B9MNA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

521460:ATHE RS05770
gene id: 521460:ATHE_RS05770
uniprot id: B9MRF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

521460:ATHE RS05360
gene id: 521460:ATHE_RS05360
uniprot id: B9MR68
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

521460:ATHE RS08700
gene id: 521460:ATHE_RS08700
uniprot id: B9MKG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

521460:ATHE RS08325
gene id: 521460:ATHE_RS08325
uniprot id: B9MKA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

521460:ATHE RS02520
gene id: 521460:ATHE_RS02520
uniprot id: B9MNV7
names: Similarity
messages: Belongs to the class-I fumarase family.

521460:ATHE RS12885
gene id: 521460:ATHE_RS12885
uniprot id: B9MP64
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

521460:ATHE RS07170
gene id: 521460:ATHE_RS07170
uniprot id: B9MS82
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

521460:ATHE RS11105
gene id: 521460:ATHE_RS11105
uniprot id: B9MM58
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

521460:ATHE RS03430
gene id: 521460:ATHE_RS03430
uniprot id: B9MQ13
names: Similarity
messages: Belongs to the RecJ family.

521460:ATHE RS06365
gene id: 521460:ATHE_RS06365
uniprot id: B9MRS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

521460:ATHE RS05585
gene id: 521460:ATHE_RS05585
uniprot id: B9MRB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

521460:ATHE RS04850
gene id: 521460:ATHE_RS04850
uniprot id: B9MQW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

521460:ATHE RS06215
gene id: 521460:ATHE_RS06215
uniprot id: B9MRP0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

521460:ATHE RS06275
gene id: 521460:ATHE_RS06275
uniprot id: B9MKB9
names: Similarity
messages: Belongs to the UPF0236 family.

521460:ATHE RS05865
gene id: 521460:ATHE_RS05865
uniprot id: B9MRG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

521460:ATHE RS10250
gene id: 521460:ATHE_RS10250
uniprot id: B9MLC7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

521460:ATHE RS14530
gene id: 521460:ATHE_RS14530
uniprot id: B9MQF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

521460:ATHE RS05220
gene id: 521460:ATHE_RS05220
uniprot id: B9MR40
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

521460:ATHE RS00880
gene id: 521460:ATHE_RS00880
uniprot id: B9MM99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS03880
gene id: 521460:ATHE_RS03880
uniprot id: B9MQ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

521460:ATHE RS06145
gene id: 521460:ATHE_RS06145
uniprot id: B9MRM6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS07705
gene id: 521460:ATHE_RS07705
uniprot id: B9MJX8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

521460:ATHE RS03135
gene id: 521460:ATHE_RS03135
uniprot id: B9MPJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS08415
gene id: 521460:ATHE_RS08415
uniprot id: B9MKB8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

521460:ATHE RS06885
gene id: 521460:ATHE_RS06885
uniprot id: B9MS25
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

521460:ATHE RS07770
gene id: 521460:ATHE_RS07770
uniprot id: B9MJZ0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

521460:ATHE RS07725
gene id: 521460:ATHE_RS07725
uniprot id: B9MJY1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS06290
gene id: 521460:ATHE_RS06290
uniprot id: B9MRQ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

521460:ATHE RS11740
gene id: 521460:ATHE_RS11740
uniprot id: B9MMV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS04260
gene id: 521460:ATHE_RS04260
uniprot id: B9MQL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS10915
gene id: 521460:ATHE_RS10915
uniprot id: B9MM25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

521460:ATHE RS03865
gene id: 521460:ATHE_RS03865
uniprot id: B9MQ95
names: Similarity
messages: Belongs to the transpeptidase family.

521460:ATHE RS10650
gene id: 521460:ATHE_RS10650
uniprot id: B9MLX2
names: Subcellular Location Annotation
messages: Secreted

521460:ATHE RS02075
gene id: 521460:ATHE_RS02075
uniprot id: B9MNM5
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

521460:ATHE RS05450
gene id: 521460:ATHE_RS05450
uniprot id: B9MR86
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

521460:ATHE RS02930
gene id: 521460:ATHE_RS02930
uniprot id: B9MPF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

521460:ATHE RS07040
gene id: 521460:ATHE_RS07040
uniprot id: B9MS56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

521460:ATHE RS07835
gene id: 521460:ATHE_RS07835
uniprot id: B9MK02
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

521460:ATHE RS06710
gene id: 521460:ATHE_RS06710
uniprot id: B9MRZ0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

521460:ATHE RS08110
gene id: 521460:ATHE_RS08110
uniprot id: B9MK55
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

521460:ATHE RS04425
gene id: 521460:ATHE_RS04425
uniprot id: B9MQN7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

521460:ATHE RS02795
gene id: 521460:ATHE_RS02795
uniprot id: B9MPC9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

521460:ATHE RS07340
gene id: 521460:ATHE_RS07340
uniprot id: B9MJR2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

521460:ATHE RS03515
gene id: 521460:ATHE_RS03515
uniprot id: B9MQ29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

521460:ATHE RS07365
gene id: 521460:ATHE_RS07365
uniprot id: B9MJR7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

521460:ATHE RS09480
gene id: 521460:ATHE_RS09480
uniprot id: B9MKW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

521460:ATHE RS08765
gene id: 521460:ATHE_RS08765
uniprot id: B9MKH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

521460:ATHE RS00530
gene id: 521460:ATHE_RS00530
uniprot id: B9MLQ8
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS10075
gene id: 521460:ATHE_RS10075
uniprot id: B9MLA0
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

521460:ATHE RS00470
gene id: 521460:ATHE_RS00470
uniprot id: B9MLP8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

521460:ATHE RS03860
gene id: 521460:ATHE_RS03860
uniprot id: B9MQ94
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS02925
gene id: 521460:ATHE_RS02925
uniprot id: B9MPF4
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS13575
gene id: 521460:ATHE_RS13575
uniprot id: B9MPW2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

521460:ATHE RS07050
gene id: 521460:ATHE_RS07050
uniprot id: B9MS58
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

521460:ATHE RS07635
gene id: 521460:ATHE_RS07635
uniprot id: B9MJW6
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS03210
gene id: 521460:ATHE_RS03210
uniprot id: B9MPK8
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

521460:ATHE RS00095
gene id: 521460:ATHE_RS00095
uniprot id: B9MLH8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.
messages: Belongs to the peptidase S24 family.

521460:ATHE RS07800
gene id: 521460:ATHE_RS07800
uniprot id: B9MJZ6
names: Similarity
messages: Belongs to the CapA family.

521460:ATHE RS05420
gene id: 521460:ATHE_RS05420
uniprot id: B9MR80
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS11615
gene id: 521460:ATHE_RS11615
uniprot id: B9MMS8
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

521460:ATHE RS10605
gene id: 521460:ATHE_RS10605
uniprot id: B9MLW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

521460:ATHE RS06520
gene id: 521460:ATHE_RS06520
uniprot id: B9MRV0
names: Similarity
messages: Belongs to the class-D beta-lactamase family.
messages: Belongs to the transpeptidase family.

521460:ATHE RS03100
gene id: 521460:ATHE_RS03100
uniprot id: B9MPI6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

521460:ATHE RS08135
gene id: 521460:ATHE_RS08135
uniprot id: B9MK61
names: Similarity
messages: Belongs to the thioredoxin family.

521460:ATHE RS03380
gene id: 521460:ATHE_RS03380
uniprot id: B9MQ06
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

521460:ATHE RS10770
gene id: 521460:ATHE_RS10770
uniprot id: B9MLZ6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

521460:ATHE RS11250
gene id: 521460:ATHE_RS11250
uniprot id: B9MMK7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS04925
gene id: 521460:ATHE_RS04925
uniprot id: B9MQY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

521460:ATHE RS07795
gene id: 521460:ATHE_RS07795
uniprot id: B9MJZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

521460:ATHE RS09595
gene id: 521460:ATHE_RS09595
uniprot id: B9MKZ3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

521460:ATHE RS01265
gene id: 521460:ATHE_RS01265
uniprot id: B9MLH5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

521460:ATHE RS04495
gene id: 521460:ATHE_RS04495
uniprot id: B9MQQ0
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS13940
gene id: 521460:ATHE_RS13940
uniprot id: B9MQF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

521460:ATHE RS02780
gene id: 521460:ATHE_RS02780
uniprot id: B9MPC6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

521460:ATHE RS04355
gene id: 521460:ATHE_RS04355
uniprot id: B9MQM5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

521460:ATHE RS03165
gene id: 521460:ATHE_RS03165
uniprot id: B9MPJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

521460:ATHE RS03315
gene id: 521460:ATHE_RS03315
uniprot id: B9MPM7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

521460:ATHE RS05845
gene id: 521460:ATHE_RS05845
uniprot id: B9MRG5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

521460:ATHE RS13230
gene id: 521460:ATHE_RS13230
uniprot id: B9MPQ1
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS11405
gene id: 521460:ATHE_RS11405
uniprot id: B9MMN8
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS05045
gene id: 521460:ATHE_RS05045
uniprot id: B9MR05
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

521460:ATHE RS08770
gene id: 521460:ATHE_RS08770
uniprot id: B9MKI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

521460:ATHE RS11770
gene id: 521460:ATHE_RS11770
uniprot id: B9MMV8
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

521460:ATHE RS02150
gene id: 521460:ATHE_RS02150
uniprot id: B9MNP0
names: Similarity
messages: Belongs to the sigma-70 factor family.

521460:ATHE RS00300
gene id: 521460:ATHE_RS00300
uniprot id: B9MLL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

521460:ATHE RS07785
gene id: 521460:ATHE_RS07785
uniprot id: B9MJZ3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

521460:ATHE RS10320
gene id: 521460:ATHE_RS10320
uniprot id: B9MLE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS08270
gene id: 521460:ATHE_RS08270
uniprot id: B9MK89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

521460:ATHE RS02785
gene id: 521460:ATHE_RS02785
uniprot id: B9MPC7
names: Function
names: Similarity
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

521460:ATHE RS00605
gene id: 521460:ATHE_RS00605
uniprot id: B9MLS3
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

521460:ATHE RS09495
gene id: 521460:ATHE_RS09495
uniprot id: B9MKX2
names: Similarity
messages: Belongs to the peptidase C40 family.

521460:ATHE RS10410
gene id: 521460:ATHE_RS10410
uniprot id: B9MLG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

521460:ATHE RS02695
gene id: 521460:ATHE_RS02695
uniprot id: B9MPA9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS09060
gene id: 521460:ATHE_RS09060
uniprot id: B9MKN7
names: Similarity
messages: Belongs to the CdaR family.

521460:ATHE RS13260
gene id: 521460:ATHE_RS13260
uniprot id: B9MPQ7
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS08595
gene id: 521460:ATHE_RS08595
uniprot id: B9MKE7
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

521460:ATHE RS09950
gene id: 521460:ATHE_RS09950
uniprot id: B9ML78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

521460:ATHE RS13270
gene id: 521460:ATHE_RS13270
uniprot id: B9MPQ9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS07370
gene id: 521460:ATHE_RS07370
uniprot id: B9MJR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

521460:ATHE RS10530
gene id: 521460:ATHE_RS10530
uniprot id: B9MLV1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

521460:ATHE RS05355
gene id: 521460:ATHE_RS05355
uniprot id: B9MR67
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

521460:ATHE RS00015
gene id: 521460:ATHE_RS00015
uniprot id: B9ML39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

521460:ATHE RS08390
gene id: 521460:ATHE_RS08390
uniprot id: B9MKB3
names: Similarity
messages: Belongs to the FlgM family.

521460:ATHE RS08540
gene id: 521460:ATHE_RS08540
uniprot id: B9MKE1
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS11800
gene id: 521460:ATHE_RS11800
uniprot id: B9MMW4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

521460:ATHE RS03740
gene id: 521460:ATHE_RS03740
uniprot id: B9MQ75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

521460:ATHE RS09550
gene id: 521460:ATHE_RS09550
uniprot id: B9MKY3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

521460:ATHE RS09020
gene id: 521460:ATHE_RS09020
uniprot id: B9MKM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

521460:ATHE RS04935
gene id: 521460:ATHE_RS04935
uniprot id: B9MQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

521460:ATHE RS06760
gene id: 521460:ATHE_RS06760
uniprot id: B9MS00
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

521460:ATHE RS06325
gene id: 521460:ATHE_RS06325
uniprot id: B9MRR2
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

521460:ATHE RS09125
gene id: 521460:ATHE_RS09125
uniprot id: B9MKQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

521460:ATHE RS00250
gene id: 521460:ATHE_RS00250
uniprot id: B9MLK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS04275
gene id: 521460:ATHE_RS04275
uniprot id: B9MQL5
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

521460:ATHE RS00270
gene id: 521460:ATHE_RS00270
uniprot id: B9MLL0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

521460:ATHE RS03075
gene id: 521460:ATHE_RS03075
uniprot id: Q44406
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

521460:ATHE RS09355
gene id: 521460:ATHE_RS09355
uniprot id: B9MKU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

521460:ATHE RS06510
gene id: 521460:ATHE_RS06510
uniprot id: B9MRU8
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

521460:ATHE RS05630
gene id: 521460:ATHE_RS05630
uniprot id: B9MRC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

521460:ATHE RS06920
gene id: 521460:ATHE_RS06920
uniprot id: B9MS32
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS05945
gene id: 521460:ATHE_RS05945
uniprot id: B9MRI5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

521460:ATHE RS11025
gene id: 521460:ATHE_RS11025
uniprot id: B9MM46
names: Similarity
messages: Belongs to the HepT RNase toxin family.

521460:ATHE RS09635
gene id: 521460:ATHE_RS09635
uniprot id: B9ML01
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS04130
gene id: 521460:ATHE_RS04130
uniprot id: B9MQI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS10545
gene id: 521460:ATHE_RS10545
uniprot id: B9MLV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

521460:ATHE RS12990
gene id: 521460:ATHE_RS12990
uniprot id: B9MP80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

521460:ATHE RS08735
gene id: 521460:ATHE_RS08735
uniprot id: B9MKH3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

521460:ATHE RS06055
gene id: 521460:ATHE_RS06055
uniprot id: B9MRK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

521460:ATHE RS13935
gene id: 521460:ATHE_RS13935
uniprot id: B9MQF4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

521460:ATHE RS10230
gene id: 521460:ATHE_RS10230
uniprot id: B9MLC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

521460:ATHE RS07670
gene id: 521460:ATHE_RS07670
uniprot id: B9MJX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

521460:ATHE RS07005
gene id: 521460:ATHE_RS07005
uniprot id: B9MS48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

521460:ATHE RS09005
gene id: 521460:ATHE_RS09005
uniprot id: B9MKM6
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

521460:ATHE RS03635
gene id: 521460:ATHE_RS03635
uniprot id: B9MQ55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

521460:ATHE RS07425
gene id: 521460:ATHE_RS07425
uniprot id: B9MJS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

521460:ATHE RS07630
gene id: 521460:ATHE_RS07630
uniprot id: B9MJW5
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS00110
gene id: 521460:ATHE_RS00110
uniprot id: B9MLI1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

521460:ATHE RS08745
gene id: 521460:ATHE_RS08745
uniprot id: B9MKH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

521460:ATHE RS10490
gene id: 521460:ATHE_RS10490
uniprot id: B9MLH6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

521460:ATHE RS09445
gene id: 521460:ATHE_RS09445
uniprot id: B9MKW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS04440
gene id: 521460:ATHE_RS04440
uniprot id: B9MQP0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS07415
gene id: 521460:ATHE_RS07415
uniprot id: B9MJS7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS00500
gene id: 521460:ATHE_RS00500
uniprot id: B9MLQ2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS03150
gene id: 521460:ATHE_RS03150
uniprot id: B9MPJ6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

521460:ATHE RS13860
gene id: 521460:ATHE_RS13860
uniprot id: B9MQD9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

521460:ATHE RS07730
gene id: 521460:ATHE_RS07730
uniprot id: B9MJY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

521460:ATHE RS06475
gene id: 521460:ATHE_RS06475
uniprot id: B9MRU1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

521460:ATHE RS11345
gene id: 521460:ATHE_RS11345
uniprot id: B9MMM6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

521460:ATHE RS00010
gene id: 521460:ATHE_RS00010
uniprot id: B9ML38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

521460:ATHE RS03535
gene id: 521460:ATHE_RS03535
uniprot id: B9MQ33
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

521460:ATHE RS06185
gene id: 521460:ATHE_RS06185
uniprot id: B9MRN4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

521460:ATHE RS01550
gene id: 521460:ATHE_RS01550
uniprot id: B9MN02
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

521460:ATHE RS06855
gene id: 521460:ATHE_RS06855
uniprot id: B9MS19
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

521460:ATHE RS09050
gene id: 521460:ATHE_RS09050
uniprot id: B9MKN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

521460:ATHE RS04480
gene id: 521460:ATHE_RS04480
uniprot id: B9MKB9
names: Similarity
messages: Belongs to the UPF0236 family.

521460:ATHE RS05425
gene id: 521460:ATHE_RS05425
uniprot id: B9MR81
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

521460:ATHE RS08675
gene id: 521460:ATHE_RS08675
uniprot id: B9MKG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

521460:ATHE RS09080
gene id: 521460:ATHE_RS09080
uniprot id: B9MKP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

521460:ATHE RS10680
gene id: 521460:ATHE_RS10680
uniprot id: B9MLX8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

521460:ATHE RS07665
gene id: 521460:ATHE_RS07665
uniprot id: B9MJX2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

521460:ATHE RS04430
gene id: 521460:ATHE_RS04430
uniprot id: B9MQN8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

521460:ATHE RS13640
gene id: 521460:ATHE_RS13640
uniprot id: B9MPX3
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

521460:ATHE RS05055
gene id: 521460:ATHE_RS05055
uniprot id: B9MR07
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

521460:ATHE RS07445
gene id: 521460:ATHE_RS07445
uniprot id: B9MJT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

521460:ATHE RS05690
gene id: 521460:ATHE_RS05690
uniprot id: B9MRD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

521460:ATHE RS00725
gene id: 521460:ATHE_RS00725
uniprot id: B9MLU3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

521460:ATHE RS01485
gene id: 521460:ATHE_RS01485
uniprot id: B9MMY9
names: Similarity
messages: Belongs to the ComB family.

521460:ATHE RS09205
gene id: 521460:ATHE_RS09205
uniprot id: B9MKR6
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

521460:ATHE RS11920
gene id: 521460:ATHE_RS11920
uniprot id: B9MNA6
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS01970
gene id: 521460:ATHE_RS01970
uniprot id: B9MN78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS01900
gene id: 521460:ATHE_RS01900
uniprot id: B9MN69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

521460:ATHE RS00550
gene id: 521460:ATHE_RS00550
uniprot id: B9MLR2
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS08350
gene id: 521460:ATHE_RS08350
uniprot id: B9MKA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

521460:ATHE RS01030
gene id: 521460:ATHE_RS01030
uniprot id: B9MMC9
names: Similarity
messages: Belongs to the DHPS family.

521460:ATHE RS10565
gene id: 521460:ATHE_RS10565
uniprot id: B9MLV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

521460:ATHE RS10405
gene id: 521460:ATHE_RS10405
uniprot id: B9MLF9
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

521460:ATHE RS03080
gene id: 521460:ATHE_RS03080
uniprot id: B9MPI1
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

521460:ATHE RS11515
gene id: 521460:ATHE_RS11515
uniprot id: B9MMQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

521460:ATHE RS06995
gene id: 521460:ATHE_RS06995
uniprot id: B9MS46
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

521460:ATHE RS01545
gene id: 521460:ATHE_RS01545
uniprot id: B9MN01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

521460:ATHE RS03385
gene id: 521460:ATHE_RS03385
uniprot id: B9MQ07
names: Similarity
messages: Belongs to the UPF0047 family.

521460:ATHE RS00135
gene id: 521460:ATHE_RS00135
uniprot id: B9MLI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

521460:ATHE RS01095
gene id: 521460:ATHE_RS01095
uniprot id: B9MME2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS03485
gene id: 521460:ATHE_RS03485
uniprot id: B9MQ23
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

521460:ATHE RS04840
gene id: 521460:ATHE_RS04840
uniprot id: B9MQW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

521460:ATHE RS02305
gene id: 521460:ATHE_RS02305
uniprot id: B9MNS0
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

521460:ATHE RS10115
gene id: 521460:ATHE_RS10115
uniprot id: B9MLA3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

521460:ATHE RS10860
gene id: 521460:ATHE_RS10860
uniprot id: B9MM14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

521460:ATHE RS11745
gene id: 521460:ATHE_RS11745
uniprot id: B9MMV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS04920
gene id: 521460:ATHE_RS04920
uniprot id: B9MQY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

521460:ATHE RS06440
gene id: 521460:ATHE_RS06440
uniprot id: B9MRT4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

521460:ATHE RS05195
gene id: 521460:ATHE_RS05195
uniprot id: B9MR35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

521460:ATHE RS02130
gene id: 521460:ATHE_RS02130
uniprot id: B9MNN6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

521460:ATHE RS10995
gene id: 521460:ATHE_RS10995
uniprot id: B9MM41
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

521460:ATHE RS07825
gene id: 521460:ATHE_RS07825
uniprot id: B9MK00
names: Similarity
messages: Belongs to the SleB family.

521460:ATHE RS10850
gene id: 521460:ATHE_RS10850
uniprot id: B9MM12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

521460:ATHE RS09055
gene id: 521460:ATHE_RS09055
uniprot id: B9MKN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

521460:ATHE RS10025
gene id: 521460:ATHE_RS10025
uniprot id: B9ML91
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

521460:ATHE RS09180
gene id: 521460:ATHE_RS09180
uniprot id: B9MKR1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS13485
gene id: 521460:ATHE_RS13485
uniprot id: B9MPV2
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

521460:ATHE RS07140
gene id: 521460:ATHE_RS07140
uniprot id: B9MS76
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

521460:ATHE RS06050
gene id: 521460:ATHE_RS06050
uniprot id: B9MRK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

521460:ATHE RS04220
gene id: 521460:ATHE_RS04220
uniprot id: B9MQK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

521460:ATHE RS06845
gene id: 521460:ATHE_RS06845
uniprot id: B9MS17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

521460:ATHE RS00625
gene id: 521460:ATHE_RS00625
uniprot id: B9MLS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

521460:ATHE RS12085
gene id: 521460:ATHE_RS12085
uniprot id: B9MND7
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

521460:ATHE RS10920
gene id: 521460:ATHE_RS10920
uniprot id: B9MM26
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

521460:ATHE RS11940
gene id: 521460:ATHE_RS11940
uniprot id: B9MNB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

521460:ATHE RS07775
gene id: 521460:ATHE_RS07775
uniprot id: B9MJZ1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

521460:ATHE RS06105
gene id: 521460:ATHE_RS06105
uniprot id: B9MRL8
names: Similarity
messages: Belongs to the asp23 family.

521460:ATHE RS05240
gene id: 521460:ATHE_RS05240
uniprot id: B9MR44
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

521460:ATHE RS09115
gene id: 521460:ATHE_RS09115
uniprot id: B9MKP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

521460:ATHE RS03200
gene id: 521460:ATHE_RS03200
uniprot id: B9MPK6
names: Similarity
messages: Belongs to the glutamine synthetase family.

521460:ATHE RS07390
gene id: 521460:ATHE_RS07390
uniprot id: B9MJS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

521460:ATHE RS08355
gene id: 521460:ATHE_RS08355
uniprot id: B9MKA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

521460:ATHE RS06500
gene id: 521460:ATHE_RS06500
uniprot id: B9MRU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

521460:ATHE RS03940
gene id: 521460:ATHE_RS03940
uniprot id: B9MQB0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

521460:ATHE RS12815
gene id: 521460:ATHE_RS12815
uniprot id: B9MP51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

521460:ATHE RS12080
gene id: 521460:ATHE_RS12080
uniprot id: B9MND6
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

521460:ATHE RS05720
gene id: 521460:ATHE_RS05720
uniprot id: B9MRE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

521460:ATHE RS02585
gene id: 521460:ATHE_RS02585
uniprot id: B9MNX0
names: Similarity
messages: Belongs to the leucine-binding protein family.

521460:ATHE RS07210
gene id: 521460:ATHE_RS07210
uniprot id: B9MS90
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS01790
gene id: 521460:ATHE_RS01790
uniprot id: B9MN49
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

521460:ATHE RS05660
gene id: 521460:ATHE_RS05660
uniprot id: B9MRC8
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

521460:ATHE RS09765
gene id: 521460:ATHE_RS09765
uniprot id: B9ML25
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

521460:ATHE RS05465
gene id: 521460:ATHE_RS05465
uniprot id: B9MR89
names: Similarity
messages: Belongs to the HypD family.

521460:ATHE RS13960
gene id: 521460:ATHE_RS13960
uniprot id: B9MKB9
names: Similarity
messages: Belongs to the UPF0236 family.

521460:ATHE RS02765
gene id: 521460:ATHE_RS02765
uniprot id: B9MPC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

521460:ATHE RS08425
gene id: 521460:ATHE_RS08425
uniprot id: B9MKB9
names: Similarity
messages: Belongs to the UPF0236 family.

521460:ATHE RS10950
gene id: 521460:ATHE_RS10950
uniprot id: B9MM32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

521460:ATHE RS09285
gene id: 521460:ATHE_RS09285
uniprot id: B9MKT0
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

521460:ATHE RS00440
gene id: 521460:ATHE_RS00440
uniprot id: B9MLP1
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

521460:ATHE RS00455
gene id: 521460:ATHE_RS00455
uniprot id: B9MKB9
names: Similarity
messages: Belongs to the UPF0236 family.

521460:ATHE RS10360
gene id: 521460:ATHE_RS10360
uniprot id: B9MLE9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

521460:ATHE RS06645
gene id: 521460:ATHE_RS06645
uniprot id: B9MRX7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

521460:ATHE RS04500
gene id: 521460:ATHE_RS04500
uniprot id: B9MQQ1
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS06860
gene id: 521460:ATHE_RS06860
uniprot id: B9MS20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

521460:ATHE RS01780
gene id: 521460:ATHE_RS01780
uniprot id: B9MN47
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

521460:ATHE RS06165
gene id: 521460:ATHE_RS06165
uniprot id: B9MRN0
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

521460:ATHE RS04385
gene id: 521460:ATHE_RS04385
uniprot id: B9MQM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS08775
gene id: 521460:ATHE_RS08775
uniprot id: B9MKI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

521460:ATHE RS08890
gene id: 521460:ATHE_RS08890
uniprot id: B9MKK3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

521460:ATHE RS13915
gene id: 521460:ATHE_RS13915
uniprot id: B9MQF0
names: Similarity
messages: Belongs to the ParB family.

521460:ATHE RS06115
gene id: 521460:ATHE_RS06115
uniprot id: B9MRM0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

521460:ATHE RS11885
gene id: 521460:ATHE_RS11885
uniprot id: B9MN99
names: Similarity
messages: Belongs to the glutamate synthase family.

521460:ATHE RS11010
gene id: 521460:ATHE_RS11010
uniprot id: B9MM44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS06395
gene id: 521460:ATHE_RS06395
uniprot id: B9MRS6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

521460:ATHE RS12355
gene id: 521460:ATHE_RS12355
uniprot id: B9MNI8
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS06205
gene id: 521460:ATHE_RS06205
uniprot id: B9MRN8
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS08645
gene id: 521460:ATHE_RS08645
uniprot id: B9MKF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

521460:ATHE RS03185
gene id: 521460:ATHE_RS03185
uniprot id: B9MPK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

521460:ATHE RS06390
gene id: 521460:ATHE_RS06390
uniprot id: B9MRS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

521460:ATHE RS05175
gene id: 521460:ATHE_RS05175
uniprot id: B9MR31
names: Similarity
messages: Belongs to the RemA family.

521460:ATHE RS09165
gene id: 521460:ATHE_RS09165
uniprot id: B9MKQ8
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

521460:ATHE RS00525
gene id: 521460:ATHE_RS00525
uniprot id: B9MLQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

521460:ATHE RS03895
gene id: 521460:ATHE_RS03895
uniprot id: B9MQA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS11350
gene id: 521460:ATHE_RS11350
uniprot id: B9MMM7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

521460:ATHE RS05300
gene id: 521460:ATHE_RS05300
uniprot id: B9MR56
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

521460:ATHE RS09795
gene id: 521460:ATHE_RS09795
uniprot id: B9ML31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

521460:ATHE RS13145
gene id: 521460:ATHE_RS13145
uniprot id: B9MPN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

521460:ATHE RS07130
gene id: 521460:ATHE_RS07130
uniprot id: B9MS74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

521460:ATHE RS09190
gene id: 521460:ATHE_RS09190
uniprot id: B9MKR3
names: Similarity
messages: Belongs to the CtsR family.

521460:ATHE RS11355
gene id: 521460:ATHE_RS11355
uniprot id: B9MMM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521460:ATHE RS07720
gene id: 521460:ATHE_RS07720
uniprot id: B9MJY0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

521460:ATHE RS02515
gene id: 521460:ATHE_RS02515
uniprot id: B9MNV6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

521460:ATHE RS10510
gene id: 521460:ATHE_RS10510
uniprot id: B9MLU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS01660
gene id: 521460:ATHE_RS01660
uniprot id: B9MN22
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521460:ATHE RS03145
gene id: 521460:ATHE_RS03145
uniprot id: B9MPJ5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

521460:ATHE RS08215
gene id: 521460:ATHE_RS08215
uniprot id: B9MK78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

521460:ATHE RS10715
gene id: 521460:ATHE_RS10715
uniprot id: B9MLY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS05650
gene id: 521460:ATHE_RS05650
uniprot id: B9MRC6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

521460:ATHE RS04200
gene id: 521460:ATHE_RS04200
uniprot id: B9MQK0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

521460:ATHE RS02880
gene id: 521460:ATHE_RS02880
uniprot id: B9MPE5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS05625
gene id: 521460:ATHE_RS05625
uniprot id: B9MRC1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

521460:ATHE RS12280
gene id: 521460:ATHE_RS12280
uniprot id: B9MNH4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

521460:ATHE RS04775
gene id: 521460:ATHE_RS04775
uniprot id: B9MQV4
names: Similarity
messages: Belongs to the intimin/invasin family.

521460:ATHE RS07900
gene id: 521460:ATHE_RS07900
uniprot id: B9MK13
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS04045
gene id: 521460:ATHE_RS04045
uniprot id: B9MQG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

521460:ATHE RS03915
gene id: 521460:ATHE_RS03915
uniprot id: B9MQA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

521460:ATHE RS10960
gene id: 521460:ATHE_RS10960
uniprot id: B9MM34
names: Similarity
messages: Belongs to the DprA/Smf family.

521460:ATHE RS05385
gene id: 521460:ATHE_RS05385
uniprot id: B9MR73
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

521460:ATHE RS13010
gene id: 521460:ATHE_RS13010
uniprot id: B9MP84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

521460:ATHE RS04235
gene id: 521460:ATHE_RS04235
uniprot id: B9MQK7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

521460:ATHE RS07870
gene id: 521460:ATHE_RS07870
uniprot id: B9MK09
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

521460:ATHE RS03115
gene id: 521460:ATHE_RS03115
uniprot id: B9MPI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

521460:ATHE RS09220
gene id: 521460:ATHE_RS09220
uniprot id: B9MKR9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

521460:ATHE RS05365
gene id: 521460:ATHE_RS05365
uniprot id: B9MR69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

521460:ATHE RS00290
gene id: 521460:ATHE_RS00290
uniprot id: B9MLL4
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

521460:ATHE RS07740
gene id: 521460:ATHE_RS07740
uniprot id: B9MJY4
names: Similarity
messages: Belongs to the peptidase M29 family.

521460:ATHE RS07125
gene id: 521460:ATHE_RS07125
uniprot id: B9MS73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

521460:ATHE RS12360
gene id: 521460:ATHE_RS12360
uniprot id: B9MNI9
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS12210
gene id: 521460:ATHE_RS12210
uniprot id: B9MNF9
names: Similarity
messages: Belongs to the PemK/MazF family.

521460:ATHE RS03655
gene id: 521460:ATHE_RS03655
uniprot id: B9MQ59
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

521460:ATHE RS11545
gene id: 521460:ATHE_RS11545
uniprot id: B9MLH5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

521460:ATHE RS00715
gene id: 521460:ATHE_RS00715
uniprot id: B9MLU1
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

521460:ATHE RS08705
gene id: 521460:ATHE_RS08705
uniprot id: B9MKG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

521460:ATHE RS12025
gene id: 521460:ATHE_RS12025
uniprot id: B9MNC6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

521460:ATHE RS02165
gene id: 521460:ATHE_RS02165
uniprot id: B9MNP3
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

521460:ATHE RS07465
gene id: 521460:ATHE_RS07465
uniprot id: B9MJT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

521460:ATHE RS05400
gene id: 521460:ATHE_RS05400
uniprot id: B9MR76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

521460:ATHE RS03960
gene id: 521460:ATHE_RS03960
uniprot id: B9MQB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS08360
gene id: 521460:ATHE_RS08360
uniprot id: B9MKA7
names: Similarity
messages: Belongs to the HepT RNase toxin family.

521460:ATHE RS06880
gene id: 521460:ATHE_RS06880
uniprot id: B9MS24
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS10355
gene id: 521460:ATHE_RS10355
uniprot id: B9MLE8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521460:ATHE RS07250
gene id: 521460:ATHE_RS07250
uniprot id: B9MS98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

521460:ATHE RS10845
gene id: 521460:ATHE_RS10845
uniprot id: B9MM11
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS12870
gene id: 521460:ATHE_RS12870
uniprot id: B9MP61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS06150
gene id: 521460:ATHE_RS06150
uniprot id: B9MRM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

521460:ATHE RS10045
gene id: 521460:ATHE_RS10045
uniprot id: B9ML95
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

521460:ATHE RS07260
gene id: 521460:ATHE_RS07260
uniprot id: B9MSA0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS08975
gene id: 521460:ATHE_RS08975
uniprot id: B9MKM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

521460:ATHE RS03030
gene id: 521460:ATHE_RS03030
uniprot id: B9MPH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

521460:ATHE RS12005
gene id: 521460:ATHE_RS12005
uniprot id: B9MNC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

521460:ATHE RS07590
gene id: 521460:ATHE_RS07590
uniprot id: B9MJV7
names: Similarity
messages: Belongs to the UPF0047 family.

521460:ATHE RS07420
gene id: 521460:ATHE_RS07420
uniprot id: B9MJS8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

521460:ATHE RS08610
gene id: 521460:ATHE_RS08610
uniprot id: B9MKF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

521460:ATHE RS03285
gene id: 521460:ATHE_RS03285
uniprot id: B9MPM2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

521460:ATHE RS02140
gene id: 521460:ATHE_RS02140
uniprot id: B9MNN8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

521460:ATHE RS07500
gene id: 521460:ATHE_RS07500
uniprot id: B9MJU4
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

521460:ATHE RS13645
gene id: 521460:ATHE_RS13645
uniprot id: B9MPX4
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

521460:ATHE RS01855
gene id: 521460:ATHE_RS01855
uniprot id: B9MN59
names: Similarity
messages: Belongs to the ThiD family.

521460:ATHE RS06245
gene id: 521460:ATHE_RS06245
uniprot id: B9MRP6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

521460:ATHE RS06420
gene id: 521460:ATHE_RS06420
uniprot id: B9MRT1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

521460:ATHE RS11600
gene id: 521460:ATHE_RS11600
uniprot id: B9MMS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

521460:ATHE RS13870
gene id: 521460:ATHE_RS13870
uniprot id: B9MQE1
names: Similarity
messages: Belongs to the class-I fumarase family.

521460:ATHE RS08810
gene id: 521460:ATHE_RS08810
uniprot id: B9MKI9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521460:ATHE RS10175
gene id: 521460:ATHE_RS10175
uniprot id: B9MLB3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

521460:ATHE RS07360
gene id: 521460:ATHE_RS07360
uniprot id: B9MJR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

521460:ATHE RS05780
gene id: 521460:ATHE_RS05780
uniprot id: B9MRF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

521460:ATHE RS11780
gene id: 521460:ATHE_RS11780
uniprot id: B9MMW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS09940
gene id: 521460:ATHE_RS09940
uniprot id: B9ML76
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

521460:ATHE RS13425
gene id: 521460:ATHE_RS13425
uniprot id: B9MPU0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

521460:ATHE RS08935
gene id: 521460:ATHE_RS08935
uniprot id: B9MKL2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

521460:ATHE RS09240
gene id: 521460:ATHE_RS09240
uniprot id: B9MKS3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

521460:ATHE RS08105
gene id: 521460:ATHE_RS08105
uniprot id: B9MK54
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

521460:ATHE RS02650
gene id: 521460:ATHE_RS02650
uniprot id: B9MNY3
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

521460:ATHE RS07070
gene id: 521460:ATHE_RS07070
uniprot id: B9MS62
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

521460:ATHE RS00385
gene id: 521460:ATHE_RS00385
uniprot id: B9MLN0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS09235
gene id: 521460:ATHE_RS09235
uniprot id: B9MKS2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

521460:ATHE RS13965
gene id: 521460:ATHE_RS13965
uniprot id: B9MQG0
names: Similarity
messages: Belongs to the GerABKA family.

521460:ATHE RS02285
gene id: 521460:ATHE_RS02285
uniprot id: B9MNR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

521460:ATHE RS07235
gene id: 521460:ATHE_RS07235
uniprot id: B9MS95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

521460:ATHE RS04110
gene id: 521460:ATHE_RS04110
uniprot id: B9MQI2
names: Similarity
messages: Belongs to the AOR/FOR family.

521460:ATHE RS05345
gene id: 521460:ATHE_RS05345
uniprot id: B9MR65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

521460:ATHE RS04190
gene id: 521460:ATHE_RS04190
uniprot id: B9MQJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

521460:ATHE RS07645
gene id: 521460:ATHE_RS07645
uniprot id: B9MJW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

521460:ATHE RS08750
gene id: 521460:ATHE_RS08750
uniprot id: B9MKH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

521460:ATHE RS02195
gene id: 521460:ATHE_RS02195
uniprot id: B9MNP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

521460:ATHE RS05265
gene id: 521460:ATHE_RS05265
uniprot id: B9MR49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

521460:ATHE RS01955
gene id: 521460:ATHE_RS01955
uniprot id: B9MN75
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

521460:ATHE RS05890
gene id: 521460:ATHE_RS05890
uniprot id: B9MRH4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

521460:ATHE RS05810
gene id: 521460:ATHE_RS05810
uniprot id: B9MRF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

521460:ATHE RS09090
gene id: 521460:ATHE_RS09090
uniprot id: B9MKP3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

521460:ATHE RS07515
gene id: 521460:ATHE_RS07515
uniprot id: B9MJU7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

521460:ATHE RS12385
gene id: 521460:ATHE_RS12385
uniprot id: B9MNJ4
names: Similarity
messages: Belongs to the peptidase A24 family.

521460:ATHE RS11860
gene id: 521460:ATHE_RS11860
uniprot id: B9MN94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

521460:ATHE RS07185
gene id: 521460:ATHE_RS07185
uniprot id: Q59156
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.

521460:ATHE RS02260
gene id: 521460:ATHE_RS02260
uniprot id: B9MNR1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

521460:ATHE RS03495
gene id: 521460:ATHE_RS03495
uniprot id: B9MQ25
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

521460:ATHE RS13755
gene id: 521460:ATHE_RS13755
uniprot id: B9MPZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

521460:ATHE RS03965
gene id: 521460:ATHE_RS03965
uniprot id: B9MQB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

521460:ATHE RS11275
gene id: 521460:ATHE_RS11275
uniprot id: B9MML2
names: Similarity
messages: Belongs to the UPF0236 family.

521460:ATHE RS02500
gene id: 521460:ATHE_RS02500
uniprot id: B9MNV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

521460:ATHE RS04940
gene id: 521460:ATHE_RS04940
uniprot id: B9MQY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

521460:ATHE RS07660
gene id: 521460:ATHE_RS07660
uniprot id: B9MJX1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

521460:ATHE RS00905
gene id: 521460:ATHE_RS00905
uniprot id: B9MMA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

521460:ATHE RS08470
gene id: 521460:ATHE_RS08470
uniprot id: B9MKC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

521460:ATHE RS00910
gene id: 521460:ATHE_RS00910
uniprot id: B9MMA5
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

521460:ATHE RS09140
gene id: 521460:ATHE_RS09140
uniprot id: B9MKQ3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

521460:ATHE RS11295
gene id: 521460:ATHE_RS11295
uniprot id: B9MML6
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS06850
gene id: 521460:ATHE_RS06850
uniprot id: B9MS18
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

521460:ATHE RS04305
gene id: 521460:ATHE_RS04305
uniprot id: B9MQL9
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS13635
gene id: 521460:ATHE_RS13635
uniprot id: B9MPX2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

521460:ATHE RS11775
gene id: 521460:ATHE_RS11775
uniprot id: B9MMV9
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

521460:ATHE RS09450
gene id: 521460:ATHE_RS09450
uniprot id: B9MKW3
names: Similarity
messages: Belongs to the GSP E family.

521460:ATHE RS07355
gene id: 521460:ATHE_RS07355
uniprot id: B9MJR5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

521460:ATHE RS06530
gene id: 521460:ATHE_RS06530
uniprot id: B9MRV2
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

521460:ATHE RS00030
gene id: 521460:ATHE_RS00030
uniprot id: B9ML43
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

521460:ATHE RS05320
gene id: 521460:ATHE_RS05320
uniprot id: B9MR60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS03785
gene id: 521460:ATHE_RS03785
uniprot id: B9MQ79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

521460:ATHE RS10580
gene id: 521460:ATHE_RS10580
uniprot id: B9MLW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

521460:ATHE RS05295
gene id: 521460:ATHE_RS05295
uniprot id: B9MR55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

521460:ATHE RS05250
gene id: 521460:ATHE_RS05250
uniprot id: B9MR46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

521460:ATHE RS12365
gene id: 521460:ATHE_RS12365
uniprot id: B9MNJ0
names: Similarity
messages: Belongs to the GSP E family.

521460:ATHE RS04710
gene id: 521460:ATHE_RS04710
uniprot id: B9MQU1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

521460:ATHE RS12945
gene id: 521460:ATHE_RS12945
uniprot id: B9MP75
names: Similarity
messages: Belongs to the hemerythrin family.

521460:ATHE RS05340
gene id: 521460:ATHE_RS05340
uniprot id: B9MR64
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521460:ATHE RS12825
gene id: 521460:ATHE_RS12825
uniprot id: B9MP53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

521460:ATHE RS03970
gene id: 521460:ATHE_RS03970
uniprot id: B9MQB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

521460:ATHE RS10305
gene id: 521460:ATHE_RS10305
uniprot id: B9MLD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

521460:ATHE RS08590
gene id: 521460:ATHE_RS08590
uniprot id: B9MKE6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

521460:ATHE RS06130
gene id: 521460:ATHE_RS06130
uniprot id: B9MRM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

521460:ATHE RS13655
gene id: 521460:ATHE_RS13655
uniprot id: B9MPX6
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

521460:ATHE RS13355
gene id: 521460:ATHE_RS13355
uniprot id: B9MPT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

521460:ATHE RS03415
gene id: 521460:ATHE_RS03415
uniprot id: B9MQ10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

521460:ATHE RS10295
gene id: 521460:ATHE_RS10295
uniprot id: B9MLD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

521460:ATHE RS07790
gene id: 521460:ATHE_RS07790
uniprot id: B9MJZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

521460:ATHE RS08245
gene id: 521460:ATHE_RS08245
uniprot id: B9MK84
names: Subcellular Location Annotation
messages: Cell membrane

521460:ATHE RS08910
gene id: 521460:ATHE_RS08910
uniprot id: B9MKK7
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

521460:ATHE RS10485
gene id: 521460:ATHE_RS10485
uniprot id: B9MLH5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

521460:ATHE RS02170
gene id: 521460:ATHE_RS02170
uniprot id: B9MNP4
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

521460:ATHE RS05965
gene id: 521460:ATHE_RS05965
uniprot id: B9MRI9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

521460:ATHE RS05025
gene id: 521460:ATHE_RS05025
uniprot id: B9MR01
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

521460:ATHE RS01650
gene id: 521460:ATHE_RS01650
uniprot id: B9MN20
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

521460:ATHE RS13975
gene id: 521460:ATHE_RS13975
uniprot id: B9MQG2
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

521460:ATHE RS06410
gene id: 521460:ATHE_RS06410
uniprot id: B9MRS9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

521460:ATHE RS05710
gene id: 521460:ATHE_RS05710
uniprot id: B9MRD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

521460:ATHE RS05460
gene id: 521460:ATHE_RS05460
uniprot id: B9MR88
names: Similarity
messages: Belongs to the HupF/HypC family.

521460:ATHE RS05995
gene id: 521460:ATHE_RS05995
uniprot id: B9MRJ5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

521460:ATHE RS07510
gene id: 521460:ATHE_RS07510
uniprot id: B9MJU6
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

521460:ATHE RS05765
gene id: 521460:ATHE_RS05765
uniprot id: B9MRF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

521460:ATHE RS04180
gene id: 521460:ATHE_RS04180
uniprot id: B9MQJ6
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS03530
gene id: 521460:ATHE_RS03530
uniprot id: B9MQ32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

521460:ATHE RS02300
gene id: 521460:ATHE_RS02300
uniprot id: B9MNR9
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS00395
gene id: 521460:ATHE_RS00395
uniprot id: B9MLN2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS08800
gene id: 521460:ATHE_RS08800
uniprot id: B9MKI7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS05390
gene id: 521460:ATHE_RS05390
uniprot id: B9MR74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

521460:ATHE RS11945
gene id: 521460:ATHE_RS11945
uniprot id: B9MNB1
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS08440
gene id: 521460:ATHE_RS08440
uniprot id: B9MKC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

521460:ATHE RS07615
gene id: 521460:ATHE_RS07615
uniprot id: B9MJW2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

521460:ATHE RS03850
gene id: 521460:ATHE_RS03850
uniprot id: B9MQ92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

521460:ATHE RS05185
gene id: 521460:ATHE_RS05185
uniprot id: B9MR33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

521460:ATHE RS08465
gene id: 521460:ATHE_RS08465
uniprot id: B9MKC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

521460:ATHE RS10315
gene id: 521460:ATHE_RS10315
uniprot id: B9MLE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS02940
gene id: 521460:ATHE_RS02940
uniprot id: B9MPF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

521460:ATHE RS02935
gene id: 521460:ATHE_RS02935
uniprot id: B9MPF6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

521460:ATHE RS04030
gene id: 521460:ATHE_RS04030
uniprot id: B9MQG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

521460:ATHE RS07115
gene id: 521460:ATHE_RS07115
uniprot id: B9MS71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

521460:ATHE RS00260
gene id: 521460:ATHE_RS00260
uniprot id: B9MLK8
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

521460:ATHE RS10525
gene id: 521460:ATHE_RS10525
uniprot id: B9MLV0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

521460:ATHE RS03225
gene id: 521460:ATHE_RS03225
uniprot id: B9MPL1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

521460:ATHE RS03810
gene id: 521460:ATHE_RS03810
uniprot id: B9MQ84
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

521460:ATHE RS08640
gene id: 521460:ATHE_RS08640
uniprot id: B9MKF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

521460:ATHE RS07525
gene id: 521460:ATHE_RS07525
uniprot id: B9MJU9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

521460:ATHE RS06690
gene id: 521460:ATHE_RS06690
uniprot id: B9MRY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

521460:ATHE RS10690
gene id: 521460:ATHE_RS10690
uniprot id: B9MLY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

521460:ATHE RS03815
gene id: 521460:ATHE_RS03815
uniprot id: B9MQ85
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

521460:ATHE RS04570
gene id: 521460:ATHE_RS04570
uniprot id: B9MQR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521460:ATHE RS11225
gene id: 521460:ATHE_RS11225
uniprot id: B9MMK2
names: Similarity
messages: Belongs to the ribulokinase family.

521460:ATHE RS07380
gene id: 521460:ATHE_RS07380
uniprot id: B9MJS0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

521460:ATHE RS04285
gene id: 521460:ATHE_RS04285
uniprot id: B9MQL7
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

521460:ATHE RS09100
gene id: 521460:ATHE_RS09100
uniprot id: B9MKP5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS08070
gene id: 521460:ATHE_RS08070
uniprot id: B9MK47
names: Similarity
messages: Belongs to the UPF0175 family.

521460:ATHE RS07100
gene id: 521460:ATHE_RS07100
uniprot id: B9MS68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

521460:ATHE RS04050
gene id: 521460:ATHE_RS04050
uniprot id: B9MQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

521460:ATHE RS01750
gene id: 521460:ATHE_RS01750
uniprot id: B9MN41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Cell membrane
messages: Probably a homodimer.

521460:ATHE RS02495
gene id: 521460:ATHE_RS02495
uniprot id: B9MNV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

521460:ATHE RS11820
gene id: 521460:ATHE_RS11820
uniprot id: B9MMW8
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS10240
gene id: 521460:ATHE_RS10240
uniprot id: B9MLC5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

521460:ATHE RS08720
gene id: 521460:ATHE_RS08720
uniprot id: B9MKH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

521460:ATHE RS12805
gene id: 521460:ATHE_RS12805
uniprot id: B9MP49
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

521460:ATHE RS00940
gene id: 521460:ATHE_RS00940
uniprot id: B9MMB1
names: Similarity
messages: Belongs to the RutC family.

521460:ATHE RS02675
gene id: 521460:ATHE_RS02675
uniprot id: B9MPA5
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS05335
gene id: 521460:ATHE_RS05335
uniprot id: B9MR63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS08180
gene id: 521460:ATHE_RS08180
uniprot id: B9MK71
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

521460:ATHE RS11690
gene id: 521460:ATHE_RS11690
uniprot id: B9MMU2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

521460:ATHE RS02110
gene id: 521460:ATHE_RS02110
uniprot id: B9MNN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS06255
gene id: 521460:ATHE_RS06255
uniprot id: B9MRP8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

521460:ATHE RS12090
gene id: 521460:ATHE_RS12090
uniprot id: B9MND8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

521460:ATHE RS01590
gene id: 521460:ATHE_RS01590
uniprot id: B9MN11
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS09770
gene id: 521460:ATHE_RS09770
uniprot id: B9ML26
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

521460:ATHE RS08945
gene id: 521460:ATHE_RS08945
uniprot id: B9MKL4
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS09625
gene id: 521460:ATHE_RS09625
uniprot id: B9MKZ9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

521460:ATHE RS09815
gene id: 521460:ATHE_RS09815
uniprot id: B9ML35
names: Similarity
messages: Belongs to the GerABKA family.

521460:ATHE RS08630
gene id: 521460:ATHE_RS08630
uniprot id: B9MKF2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

521460:ATHE RS07450
gene id: 521460:ATHE_RS07450
uniprot id: B9MJT4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

521460:ATHE RS11950
gene id: 521460:ATHE_RS11950
uniprot id: B9MNB2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS00935
gene id: 521460:ATHE_RS00935
uniprot id: B9MMB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

521460:ATHE RS09370
gene id: 521460:ATHE_RS09370
uniprot id: B9MKU7
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

521460:ATHE RS04855
gene id: 521460:ATHE_RS04855
uniprot id: B9MQW9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

521460:ATHE RS06715
gene id: 521460:ATHE_RS06715
uniprot id: B9MRZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

521460:ATHE RS13255
gene id: 521460:ATHE_RS13255
uniprot id: B9MPQ6
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS08600
gene id: 521460:ATHE_RS08600
uniprot id: B9MKE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS00475
gene id: 521460:ATHE_RS00475
uniprot id: B9MLP9
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

521460:ATHE RS10285
gene id: 521460:ATHE_RS10285
uniprot id: B9MLD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

521460:ATHE RS13005
gene id: 521460:ATHE_RS13005
uniprot id: B9MP83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS06535
gene id: 521460:ATHE_RS06535
uniprot id: B9MRV3
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

521460:ATHE RS05805
gene id: 521460:ATHE_RS05805
uniprot id: B9MRF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

521460:ATHE RS07180
gene id: 521460:ATHE_RS07180
uniprot id: B9MS84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

521460:ATHE RS11805
gene id: 521460:ATHE_RS11805
uniprot id: B9MMW5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

521460:ATHE RS07165
gene id: 521460:ATHE_RS07165
uniprot id: B9MS81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

521460:ATHE RS07600
gene id: 521460:ATHE_RS07600
uniprot id: B9MJV9
names: Similarity
messages: Belongs to the peptidase S16 family.

521460:ATHE RS05850
gene id: 521460:ATHE_RS05850
uniprot id: B9MRG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

521460:ATHE RS05525
gene id: 521460:ATHE_RS05525
uniprot id: B9MRA1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

521460:ATHE RS09665
gene id: 521460:ATHE_RS09665
uniprot id: B9ML07
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

521460:ATHE RS06310
gene id: 521460:ATHE_RS06310
uniprot id: B9MRQ9
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

521460:ATHE RS08650
gene id: 521460:ATHE_RS08650
uniprot id: B9MKF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

521460:ATHE RS08710
gene id: 521460:ATHE_RS08710
uniprot id: B9MKG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

521460:ATHE RS07760
gene id: 521460:ATHE_RS07760
uniprot id: B9MJY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

521460:ATHE RS06620
gene id: 521460:ATHE_RS06620
uniprot id: B9MRX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

521460:ATHE RS10245
gene id: 521460:ATHE_RS10245
uniprot id: B9MLC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

521460:ATHE RS10550
gene id: 521460:ATHE_RS10550
uniprot id: B9MLV4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

521460:ATHE RS04270
gene id: 521460:ATHE_RS04270
uniprot id: B9MQL4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS07350
gene id: 521460:ATHE_RS07350
uniprot id: B9MJR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

521460:ATHE RS04995
gene id: 521460:ATHE_RS04995
uniprot id: B9MQZ5
names: Similarity
messages: Belongs to the asp23 family.

521460:ATHE RS10200
gene id: 521460:ATHE_RS10200
uniprot id: B9MLB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS04085
gene id: 521460:ATHE_RS04085
uniprot id: B9MQH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

521460:ATHE RS06875
gene id: 521460:ATHE_RS06875
uniprot id: B9MS23
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

521460:ATHE RS10805
gene id: 521460:ATHE_RS10805
uniprot id: B9MM03
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

521460:ATHE RS03645
gene id: 521460:ATHE_RS03645
uniprot id: B9MQ57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

521460:ATHE RS07015
gene id: 521460:ATHE_RS07015
uniprot id: B9MS50
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

521460:ATHE RS03925
gene id: 521460:ATHE_RS03925
uniprot id: B9MQA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

521460:ATHE RS08780
gene id: 521460:ATHE_RS08780
uniprot id: B9MKI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

521460:ATHE RS10370
gene id: 521460:ATHE_RS10370
uniprot id: B9MLF2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

521460:ATHE RS03175
gene id: 521460:ATHE_RS03175
uniprot id: B9MPK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

521460:ATHE RS09960
gene id: 521460:ATHE_RS09960
uniprot id: B9ML80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

521460:ATHE RS08525
gene id: 521460:ATHE_RS08525
uniprot id: B9MKD8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

521460:ATHE RS05610
gene id: 521460:ATHE_RS05610
uniprot id: B9MRB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

521460:ATHE RS03095
gene id: 521460:ATHE_RS03095
uniprot id: B9MPI4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

521460:ATHE RS09575
gene id: 521460:ATHE_RS09575
uniprot id: B9MKY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

521460:ATHE RS05275
gene id: 521460:ATHE_RS05275
uniprot id: B9MR51
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

521460:ATHE RS11490
gene id: 521460:ATHE_RS11490
uniprot id: B9MMQ3
names: Similarity
messages: Belongs to the UPF0251 family.

521460:ATHE RS02760
gene id: 521460:ATHE_RS02760
uniprot id: B9MPC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

521460:ATHE RS01325
gene id: 521460:ATHE_RS01325
uniprot id: B9MMJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

521460:ATHE RS04010
gene id: 521460:ATHE_RS04010
uniprot id: B9MQC4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS07780
gene id: 521460:ATHE_RS07780
uniprot id: B9MJZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

521460:ATHE RS13875
gene id: 521460:ATHE_RS13875
uniprot id: B9MQE2
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS12480
gene id: 521460:ATHE_RS12480
uniprot id: B9MNL1
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

521460:ATHE RS10935
gene id: 521460:ATHE_RS10935
uniprot id: B9MM29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

521460:ATHE RS01530
gene id: 521460:ATHE_RS01530
uniprot id: B9MMZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

521460:ATHE RS06415
gene id: 521460:ATHE_RS06415
uniprot id: B9MRT0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

521460:ATHE RS03450
gene id: 521460:ATHE_RS03450
uniprot id: B9MQ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

521460:ATHE RS01060
gene id: 521460:ATHE_RS01060
uniprot id: B9MMD5
names: Similarity
messages: Belongs to the PspA/IM30 family.

521460:ATHE RS12925
gene id: 521460:ATHE_RS12925
uniprot id: B9MP71
names: Similarity
messages: Belongs to the hemerythrin family.

521460:ATHE RS12860
gene id: 521460:ATHE_RS12860
uniprot id: B9MP59
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS03955
gene id: 521460:ATHE_RS03955
uniprot id: B9MQB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

521460:ATHE RS10445
gene id: 521460:ATHE_RS10445
uniprot id: B9MLG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS13195
gene id: 521460:ATHE_RS13195
uniprot id: B9MPP4
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS03755
gene id: 521460:ATHE_RS03755
uniprot id: B9MQ78
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

521460:ATHE RS08485
gene id: 521460:ATHE_RS08485
uniprot id: B9MKD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

521460:ATHE RS01150
gene id: 521460:ATHE_RS01150
uniprot id: B9MMF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

521460:ATHE RS10870
gene id: 521460:ATHE_RS10870
uniprot id: B9MM16
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

521460:ATHE RS05290
gene id: 521460:ATHE_RS05290
uniprot id: B9MR54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

521460:ATHE RS09810
gene id: 521460:ATHE_RS09810
uniprot id: B9ML34
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

521460:ATHE RS05180
gene id: 521460:ATHE_RS05180
uniprot id: B9MR32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

521460:ATHE RS04845
gene id: 521460:ATHE_RS04845
uniprot id: B9MQW7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

521460:ATHE RS11985
gene id: 521460:ATHE_RS11985
uniprot id: B9MNB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

521460:ATHE RS10825
gene id: 521460:ATHE_RS10825
uniprot id: B9MM07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

521460:ATHE RS00005
gene id: 521460:ATHE_RS00005
uniprot id: B9ML36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

521460:ATHE RS07240
gene id: 521460:ATHE_RS07240
uniprot id: B9MS96
names: Similarity
messages: Belongs to the SAICAR synthetase family.

521460:ATHE RS06675
gene id: 521460:ATHE_RS06675
uniprot id: B9MRY3
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS02755
gene id: 521460:ATHE_RS02755
uniprot id: B9MPC1
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

521460:ATHE RS09105
gene id: 521460:ATHE_RS09105
uniprot id: B9MKP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

521460:ATHE RS04650
gene id: 521460:ATHE_RS04650
uniprot id: B9MQS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

521460:ATHE RS13275
gene id: 521460:ATHE_RS13275
uniprot id: B9MPR2
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

521460:ATHE RS08340
gene id: 521460:ATHE_RS08340
uniprot id: B9MKA3
names: Similarity
messages: Belongs to the HepT RNase toxin family.

521460:ATHE RS09745
gene id: 521460:ATHE_RS09745
uniprot id: B9ML21
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

521460:ATHE RS05285
gene id: 521460:ATHE_RS05285
uniprot id: B9MR53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

521460:ATHE RS09615
gene id: 521460:ATHE_RS09615
uniprot id: B9MKZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS00145
gene id: 521460:ATHE_RS00145
uniprot id: B9MLI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

521460:ATHE RS10820
gene id: 521460:ATHE_RS10820
uniprot id: B9MM06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

521460:ATHE RS11665
gene id: 521460:ATHE_RS11665
uniprot id: B9MMT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

521460:ATHE RS07485
gene id: 521460:ATHE_RS07485
uniprot id: B9MJU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

521460:ATHE RS12855
gene id: 521460:ATHE_RS12855
uniprot id: B9MP58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

521460:ATHE RS02700
gene id: 521460:ATHE_RS02700
uniprot id: B9MPB0
names: Similarity
messages: Belongs to the UPF0145 family.

521460:ATHE RS10855
gene id: 521460:ATHE_RS10855
uniprot id: B9MM13
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

521460:ATHE RS13415
gene id: 521460:ATHE_RS13415
uniprot id: B9MPT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

521460:ATHE RS00995
gene id: 521460:ATHE_RS00995
uniprot id: B9MMC2
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS04070
gene id: 521460:ATHE_RS04070
uniprot id: B9MQH4
names: Similarity
messages: Belongs to the IMPACT family.

521460:ATHE RS13895
gene id: 521460:ATHE_RS13895
uniprot id: B9MQE6
names: Similarity
messages: Belongs to the ParB family.

521460:ATHE RS05645
gene id: 521460:ATHE_RS05645
uniprot id: B9MRC5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

521460:ATHE RS08805
gene id: 521460:ATHE_RS08805
uniprot id: B9MKI8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

521460:ATHE RS05675
gene id: 521460:ATHE_RS05675
uniprot id: B9MRD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

521460:ATHE RS10390
gene id: 521460:ATHE_RS10390
uniprot id: B9MLF6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

521460:ATHE RS13140
gene id: 521460:ATHE_RS13140
uniprot id: B9MPN3
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

521460:ATHE RS13920
gene id: 521460:ATHE_RS13920
uniprot id: B9MQF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

521460:ATHE RS00990
gene id: 521460:ATHE_RS00990
uniprot id: B9MMC1
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS07480
gene id: 521460:ATHE_RS07480
uniprot id: B9MJU0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

521460:ATHE RS06665
gene id: 521460:ATHE_RS06665
uniprot id: B9MRY1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

521460:ATHE RS02960
gene id: 521460:ATHE_RS02960
uniprot id: B9MPG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS13650
gene id: 521460:ATHE_RS13650
uniprot id: B9MPX5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

521460:ATHE RS04705
gene id: 521460:ATHE_RS04705
uniprot id: B9MQU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS08475
gene id: 521460:ATHE_RS08475
uniprot id: B9MKC8
names: Similarity
messages: Belongs to the TrpF family.

521460:ATHE RS07930
gene id: 521460:ATHE_RS07930
uniprot id: B9MK20
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS09560
gene id: 521460:ATHE_RS09560
uniprot id: B9MKY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

521460:ATHE RS10830
gene id: 521460:ATHE_RS10830
uniprot id: B9MM08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

521460:ATHE RS03325
gene id: 521460:ATHE_RS03325
uniprot id: B9MPM9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

521460:ATHE RS02555
gene id: 521460:ATHE_RS02555
uniprot id: B9MNW4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

521460:ATHE RS00255
gene id: 521460:ATHE_RS00255
uniprot id: B9MLK7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

521460:ATHE RS06540
gene id: 521460:ATHE_RS06540
uniprot id: B9MRV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

521460:ATHE RS06005
gene id: 521460:ATHE_RS06005
uniprot id: B9MRJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

521460:ATHE RS07205
gene id: 521460:ATHE_RS07205
uniprot id: B9MS89
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

521460:ATHE RS08480
gene id: 521460:ATHE_RS08480
uniprot id: B9MKC9
names: Similarity
messages: Belongs to the TrpC family.

521460:ATHE RS13180
gene id: 521460:ATHE_RS13180
uniprot id: B9MPP1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

521460:ATHE RS00425
gene id: 521460:ATHE_RS00425
uniprot id: B9MLN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS05605
gene id: 521460:ATHE_RS05605
uniprot id: B9MRB7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

521460:ATHE RS10965
gene id: 521460:ATHE_RS10965
uniprot id: B9MM35
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

521460:ATHE RS10505
gene id: 521460:ATHE_RS10505
uniprot id: B9MLU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS05985
gene id: 521460:ATHE_RS05985
uniprot id: B9MRJ3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

521460:ATHE RS01555
gene id: 521460:ATHE_RS01555
uniprot id: B9MN03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

521460:ATHE RS11905
gene id: 521460:ATHE_RS11905
uniprot id: B9MNA3
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS13930
gene id: 521460:ATHE_RS13930
uniprot id: B9MQF3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS03320
gene id: 521460:ATHE_RS03320
uniprot id: B9MPM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

521460:ATHE RS11955
gene id: 521460:ATHE_RS11955
uniprot id: B9MNB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS05895
gene id: 521460:ATHE_RS05895
uniprot id: B9MRH5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521460:ATHE RS06095
gene id: 521460:ATHE_RS06095
uniprot id: B9MRL6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

521460:ATHE RS08660
gene id: 521460:ATHE_RS08660
uniprot id: B9MKF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

521460:ATHE RS08855
gene id: 521460:ATHE_RS08855
uniprot id: B9MKJ6
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS07030
gene id: 521460:ATHE_RS07030
uniprot id: B9MS54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

521460:ATHE RS06260
gene id: 521460:ATHE_RS06260
uniprot id: B9MRP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

521460:ATHE RS13910
gene id: 521460:ATHE_RS13910
uniprot id: B9MQE9
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

521460:ATHE RS13175
gene id: 521460:ATHE_RS13175
uniprot id: B9MPP0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

521460:ATHE RS02980
gene id: 521460:ATHE_RS02980
uniprot id: B9MPG5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS13050
gene id: 521460:ATHE_RS13050
uniprot id: B9MP92
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

521460:ATHE RS13330
gene id: 521460:ATHE_RS13330
uniprot id: B9MPS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

521460:ATHE RS04875
gene id: 521460:ATHE_RS04875
uniprot id: B9MQX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

521460:ATHE RS09455
gene id: 521460:ATHE_RS09455
uniprot id: B9MKW4
names: Similarity
messages: Belongs to the GSP E family.

521460:ATHE RS09160
gene id: 521460:ATHE_RS09160
uniprot id: B9MKQ7
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS05260
gene id: 521460:ATHE_RS05260
uniprot id: B9MR48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

521460:ATHE RS00645
gene id: 521460:ATHE_RS00645
uniprot id: B9MLT0
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

521460:ATHE RS06065
gene id: 521460:ATHE_RS06065
uniprot id: B9MRL0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

521460:ATHE RS06035
gene id: 521460:ATHE_RS06035
uniprot id: B9MRK4
names: Similarity
messages: Belongs to the UPF0297 family.

521460:ATHE RS02815
gene id: 521460:ATHE_RS02815
uniprot id: B9MPD2
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

521460:ATHE RS08815
gene id: 521460:ATHE_RS08815
uniprot id: B9MKJ0
names: Similarity
messages: Belongs to the peptidase M18 family.

521460:ATHE RS11785
gene id: 521460:ATHE_RS11785
uniprot id: B9MMW1
names: Similarity
messages: Belongs to the peptidase S41A family.

521460:ATHE RS02220
gene id: 521460:ATHE_RS02220
uniprot id: B9MNQ3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS10810
gene id: 521460:ATHE_RS10810
uniprot id: B9MM04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

521460:ATHE RS07345
gene id: 521460:ATHE_RS07345
uniprot id: B9MJR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

521460:ATHE RS07470
gene id: 521460:ATHE_RS07470
uniprot id: B9MJT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

521460:ATHE RS06090
gene id: 521460:ATHE_RS06090
uniprot id: B9MRL5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS10220
gene id: 521460:ATHE_RS10220
uniprot id: B9MLC1
names: Similarity
messages: Belongs to the glutamate synthase family.

521460:ATHE RS05200
gene id: 521460:ATHE_RS05200
uniprot id: B9MR36
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

521460:ATHE RS06790
gene id: 521460:ATHE_RS06790
uniprot id: B9MS06
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

521460:ATHE RS07215
gene id: 521460:ATHE_RS07215
uniprot id: B9MS91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

521460:ATHE RS03090
gene id: 521460:ATHE_RS03090
uniprot id: Q44408
names: Cofactor
names: Similarity
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.

521460:ATHE RS06230
gene id: 521460:ATHE_RS06230
uniprot id: B9MRP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

521460:ATHE RS10735
gene id: 521460:ATHE_RS10735
uniprot id: B9MLY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

521460:ATHE RS09110
gene id: 521460:ATHE_RS09110
uniprot id: B9MKP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

521460:ATHE RS01145
gene id: 521460:ATHE_RS01145
uniprot id: B9MMF1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

521460:ATHE RS07545
gene id: 521460:ATHE_RS07545
uniprot id: B9MJV2
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS09700
gene id: 521460:ATHE_RS09700
uniprot id: B9ML12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS03500
gene id: 521460:ATHE_RS03500
uniprot id: B9MQ26
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

521460:ATHE RS11960
gene id: 521460:ATHE_RS11960
uniprot id: B9MNB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS07820
gene id: 521460:ATHE_RS07820
uniprot id: B9MJZ9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

521460:ATHE RS05670
gene id: 521460:ATHE_RS05670
uniprot id: B9MRD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

521460:ATHE RS09430
gene id: 521460:ATHE_RS09430
uniprot id: B9MKV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

521460:ATHE RS09845
gene id: 521460:ATHE_RS09845
uniprot id: B9ML59
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS07155
gene id: 521460:ATHE_RS07155
uniprot id: B9MS79
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

521460:ATHE RS00860
gene id: 521460:ATHE_RS00860
uniprot id: B9MM95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS06505
gene id: 521460:ATHE_RS06505
uniprot id: B9MRU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

521460:ATHE RS11110
gene id: 521460:ATHE_RS11110
uniprot id: B9MM59
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

521460:ATHE RS02770
gene id: 521460:ATHE_RS02770
uniprot id: B9MPC4
names: Similarity
messages: Belongs to the UPF0758 family.

521460:ATHE RS04380
gene id: 521460:ATHE_RS04380
uniprot id: B9MQM8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

521460:ATHE RS03885
gene id: 521460:ATHE_RS03885
uniprot id: B9MQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

521460:ATHE RS05395
gene id: 521460:ATHE_RS05395
uniprot id: B9MR75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

521460:ATHE RS12035
gene id: 521460:ATHE_RS12035
uniprot id: B9MNC8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

521460:ATHE RS09460
gene id: 521460:ATHE_RS09460
uniprot id: B9MKW5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS13775
gene id: 521460:ATHE_RS13775
uniprot id: B9MPZ6
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

521460:ATHE RS02245
gene id: 521460:ATHE_RS02245
uniprot id: B9MNQ8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

521460:ATHE RS04055
gene id: 521460:ATHE_RS04055
uniprot id: B9MQH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

521460:ATHE RS01760
gene id: 521460:ATHE_RS01760
uniprot id: B9MN43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

521460:ATHE RS06100
gene id: 521460:ATHE_RS06100
uniprot id: B9MRL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

521460:ATHE RS06265
gene id: 521460:ATHE_RS06265
uniprot id: B9MRQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

521460:ATHE RS03195
gene id: 521460:ATHE_RS03195
uniprot id: B9MPK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

521460:ATHE RS06575
gene id: 521460:ATHE_RS06575
uniprot id: B9MRW1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

521460:ATHE RS06720
gene id: 521460:ATHE_RS06720
uniprot id: B9MRZ2
names: Similarity
messages: Belongs to the YggT family.

521460:ATHE RS09835
gene id: 521460:ATHE_RS09835
uniprot id: B9ML57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

521460:ATHE RS09610
gene id: 521460:ATHE_RS09610
uniprot id: B9MKZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS07330
gene id: 521460:ATHE_RS07330
uniprot id: B9MJR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

521460:ATHE RS12015
gene id: 521460:ATHE_RS12015
uniprot id: B9MNC4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

521460:ATHE RS07265
gene id: 521460:ATHE_RS07265
uniprot id: B9MSA1
names: Similarity
messages: Belongs to the HypE family.

521460:ATHE RS01495
gene id: 521460:ATHE_RS01495
uniprot id: B9MMZ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS03620
gene id: 521460:ATHE_RS03620
uniprot id: B9MKB9
names: Similarity
messages: Belongs to the UPF0236 family.

521460:ATHE RS07245
gene id: 521460:ATHE_RS07245
uniprot id: B9MS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

521460:ATHE RS10895
gene id: 521460:ATHE_RS10895
uniprot id: B9MM21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS06640
gene id: 521460:ATHE_RS06640
uniprot id: B9MRX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

521460:ATHE RS06660
gene id: 521460:ATHE_RS06660
uniprot id: B9MRY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

521460:ATHE RS04140
gene id: 521460:ATHE_RS04140
uniprot id: B9MQI8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

521460:ATHE RS10335
gene id: 521460:ATHE_RS10335
uniprot id: B9MLE4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

521460:ATHE RS07520
gene id: 521460:ATHE_RS07520
uniprot id: B9MJU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

521460:ATHE RS03445
gene id: 521460:ATHE_RS03445
uniprot id: B9MQ16
names: Similarity
messages: Belongs to the UPF0342 family.

521460:ATHE RS06730
gene id: 521460:ATHE_RS06730
uniprot id: B9MRZ4
names: Subcellular Location Annotation
messages: Cytoplasm

521460:ATHE RS07195
gene id: 521460:ATHE_RS07195
uniprot id: B9MS87
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

521460:ATHE RS10740
gene id: 521460:ATHE_RS10740
uniprot id: B9MLZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

521460:ATHE RS05030
gene id: 521460:ATHE_RS05030
uniprot id: B9MR02
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521460:ATHE RS10475
gene id: 521460:ATHE_RS10475
uniprot id: B9MLH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

521460:ATHE RS07230
gene id: 521460:ATHE_RS07230
uniprot id: B9MS94
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

521460:ATHE RS03490
gene id: 521460:ATHE_RS03490
uniprot id: B9MQ24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

521460:ATHE RS05170
gene id: 521460:ATHE_RS05170
uniprot id: B9MR30
names: Similarity
messages: Belongs to the YicC/YloC family.

521460:ATHE RS01180
gene id: 521460:ATHE_RS01180
uniprot id: B9MMF8
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS05520
gene id: 521460:ATHE_RS05520
uniprot id: B9MRA0
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

521460:ATHE RS03065
gene id: 521460:ATHE_RS03065
uniprot id: B9MPH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS07530
gene id: 521460:ATHE_RS07530
uniprot id: B9MJV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

521460:ATHE RS03070
gene id: 521460:ATHE_RS03070
uniprot id: B9MPH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS05280
gene id: 521460:ATHE_RS05280
uniprot id: B9MR52
names: Similarity
messages: Belongs to the ribF family.

521460:ATHE RS08755
gene id: 521460:ATHE_RS08755
uniprot id: B9MKH7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

521460:ATHE RS05370
gene id: 521460:ATHE_RS05370
uniprot id: B9MR70
names: Similarity
messages: Belongs to the MotB family.

521460:ATHE RS01975
gene id: 521460:ATHE_RS01975
uniprot id: B9MN79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS06330
gene id: 521460:ATHE_RS06330
uniprot id: B9MRR3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

521460:ATHE RS10945
gene id: 521460:ATHE_RS10945
uniprot id: B9MM31
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

521460:ATHE RS03735
gene id: 521460:ATHE_RS03735
uniprot id: B9MQ74
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

521460:ATHE RS03525
gene id: 521460:ATHE_RS03525
uniprot id: B9MQ31
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

521460:ATHE RS08030
gene id: 521460:ATHE_RS08030
uniprot id: B9MK39
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

521460:ATHE RS02255
gene id: 521460:ATHE_RS02255
uniprot id: B9MNR0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

521460:ATHE RS10570
gene id: 521460:ATHE_RS10570
uniprot id: B9MLV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

521460:ATHE RS10930
gene id: 521460:ATHE_RS10930
uniprot id: B9MM28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

521460:ATHE RS02485
gene id: 521460:ATHE_RS02485
uniprot id: B9MNU9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

521460:ATHE RS04715
gene id: 521460:ATHE_RS04715
uniprot id: B9MQU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521460:ATHE RS10395
gene id: 521460:ATHE_RS10395
uniprot id: B9MLF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

521460:ATHE RS11135
gene id: 521460:ATHE_RS11135
uniprot id: B9MM63
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS10300
gene id: 521460:ATHE_RS10300
uniprot id: B9MLD7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

521460:ATHE RS05020
gene id: 521460:ATHE_RS05020
uniprot id: B9MR00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

521460:ATHE RS08760
gene id: 521460:ATHE_RS08760
uniprot id: B9MKH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

521460:ATHE RS03260
gene id: 521460:ATHE_RS03260
uniprot id: B9MPL8
names: Similarity
messages: Belongs to the threonine synthase family.

521460:ATHE RS05235
gene id: 521460:ATHE_RS05235
uniprot id: B9MR43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

521460:ATHE RS12810
gene id: 521460:ATHE_RS12810
uniprot id: B9MP50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

521460:ATHE RS11700
gene id: 521460:ATHE_RS11700
uniprot id: B9MMU4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

521460:ATHE RS08905
gene id: 521460:ATHE_RS08905
uniprot id: B9MKK6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS01570
gene id: 521460:ATHE_RS01570
uniprot id: B9MN06
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

521460:ATHE RS12820
gene id: 521460:ATHE_RS12820
uniprot id: B9MP52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

521460:ATHE RS03840
gene id: 521460:ATHE_RS03840
uniprot id: B9MQ90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

521460:ATHE RS08725
gene id: 521460:ATHE_RS08725
uniprot id: B9MKH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

521460:ATHE RS12290
gene id: 521460:ATHE_RS12290
uniprot id: B9MNH6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

521460:ATHE RS05580
gene id: 521460:ATHE_RS05580
uniprot id: B9MRB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

521460:ATHE RS10675
gene id: 521460:ATHE_RS10675
uniprot id: B9MLX7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

521460:ATHE RS11625
gene id: 521460:ATHE_RS11625
uniprot id: B9MMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS05205
gene id: 521460:ATHE_RS05205
uniprot id: B9MR37
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

521460:ATHE RS00215
gene id: 521460:ATHE_RS00215
uniprot id: B9MLK1
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS13340
gene id: 521460:ATHE_RS13340
uniprot id: B9MPS7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521460:ATHE RS09805
gene id: 521460:ATHE_RS09805
uniprot id: B9ML33
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

521460:ATHE RS13220
gene id: 521460:ATHE_RS13220
uniprot id: B9MPP9
names: Subcellular Location Annotation
messages: Secreted

521460:ATHE RS06180
gene id: 521460:ATHE_RS06180
uniprot id: B9MRN3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

521460:ATHE RS07095
gene id: 521460:ATHE_RS07095
uniprot id: B9MS67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

521460:ATHE RS10625
gene id: 521460:ATHE_RS10625
uniprot id: B9MLW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS06240
gene id: 521460:ATHE_RS06240
uniprot id: B9MRP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

521460:ATHE RS01115
gene id: 521460:ATHE_RS01115
uniprot id: B9MME5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Monomer.

521460:ATHE RS06940
gene id: 521460:ATHE_RS06940
uniprot id: B9MS36
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

521460:ATHE RS01985
gene id: 521460:ATHE_RS01985
uniprot id: B9MN81
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

521460:ATHE RS08680
gene id: 521460:ATHE_RS08680
uniprot id: B9MKG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

521460:ATHE RS05990
gene id: 521460:ATHE_RS05990
uniprot id: B9MRJ4
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

521460:ATHE RS10380
gene id: 521460:ATHE_RS10380
uniprot id: B9MLF4
names: Similarity
messages: Belongs to the P(II) protein family.

521460:ATHE RS07220
gene id: 521460:ATHE_RS07220
uniprot id: B9MS92
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

521460:ATHE RS06680
gene id: 521460:ATHE_RS06680
uniprot id: B9MRY4
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS04870
gene id: 521460:ATHE_RS04870
uniprot id: B9MQX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

521460:ATHE RS07145
gene id: 521460:ATHE_RS07145
uniprot id: B9MS77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS04915
gene id: 521460:ATHE_RS04915
uniprot id: B9MQX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

521460:ATHE RS04835
gene id: 521460:ATHE_RS04835
uniprot id: B9MQW5
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

521460:ATHE RS07765
gene id: 521460:ATHE_RS07765
uniprot id: B9MJY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

521460:ATHE RS08965
gene id: 521460:ATHE_RS08965
uniprot id: B9MKL8
names: Similarity
messages: Belongs to the BMP lipoprotein family.

521460:ATHE RS08505
gene id: 521460:ATHE_RS08505
uniprot id: B9MKD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

521460:ATHE RS08295
gene id: 521460:ATHE_RS08295
uniprot id: B9MK94
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

521460:ATHE RS08450
gene id: 521460:ATHE_RS08450
uniprot id: B9MKC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

521460:ATHE RS06200
gene id: 521460:ATHE_RS06200
uniprot id: B9MRN7
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS02505
gene id: 521460:ATHE_RS02505
uniprot id: B9MNV4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

521460:ATHE RS11630
gene id: 521460:ATHE_RS11630
uniprot id: B9MMT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS09215
gene id: 521460:ATHE_RS09215
uniprot id: B9MKR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

521460:ATHE RS03805
gene id: 521460:ATHE_RS03805
uniprot id: B9MQ83
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

521460:ATHE RS04700
gene id: 521460:ATHE_RS04700
uniprot id: B9MQT9
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

521460:ATHE RS08690
gene id: 521460:ATHE_RS08690
uniprot id: B9MKG4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

521460:ATHE RS09170
gene id: 521460:ATHE_RS09170
uniprot id: B9MKQ9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

521460:ATHE RS05785
gene id: 521460:ATHE_RS05785
uniprot id: B9MRF4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

521460:ATHE RS07035
gene id: 521460:ATHE_RS07035
uniprot id: B9MS55
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

521460:ATHE RS00620
gene id: 521460:ATHE_RS00620
uniprot id: B9MLS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

521460:ATHE RS05435
gene id: 521460:ATHE_RS05435
uniprot id: B9MR83
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Belongs to the complex I 49 kDa subunit family.

521460:ATHE RS06020
gene id: 521460:ATHE_RS06020
uniprot id: B9MRK1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

521460:ATHE RS07655
gene id: 521460:ATHE_RS07655
uniprot id: B9MJX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

521460:ATHE RS05190
gene id: 521460:ATHE_RS05190
uniprot id: B9MR34
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS13955
gene id: 521460:ATHE_RS13955
uniprot id: B9MQF8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

521460:ATHE RS08375
gene id: 521460:ATHE_RS08375
uniprot id: B9MKB0
names: Similarity
messages: Belongs to the bacterial flagellin family.

521460:ATHE RS05795
gene id: 521460:ATHE_RS05795
uniprot id: B9MRF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

521460:ATHE RS09070
gene id: 521460:ATHE_RS09070
uniprot id: B9MKN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

521460:ATHE RS08980
gene id: 521460:ATHE_RS08980
uniprot id: B9MKM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

521460:ATHE RS04685
gene id: 521460:ATHE_RS04685
uniprot id: B9MQT6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

521460:ATHE RS03190
gene id: 521460:ATHE_RS03190
uniprot id: B9MPK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

521460:ATHE RS05305
gene id: 521460:ATHE_RS05305
uniprot id: B9MR57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

521460:ATHE RS06655
gene id: 521460:ATHE_RS06655
uniprot id: B9MRX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

521460:ATHE RS05380
gene id: 521460:ATHE_RS05380
uniprot id: B9MR72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

521460:ATHE RS06795
gene id: 521460:ATHE_RS06795
uniprot id: B9MS07
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

521460:ATHE RS02825
gene id: 521460:ATHE_RS02825
uniprot id: B9MPD4
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS09945
gene id: 521460:ATHE_RS09945
uniprot id: B9ML77
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

521460:ATHE RS10660
gene id: 521460:ATHE_RS10660
uniprot id: B9MLX4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

521460:ATHE RS09785
gene id: 521460:ATHE_RS09785
uniprot id: B9ML29
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

521460:ATHE RS04945
gene id: 521460:ATHE_RS04945
uniprot id: B9MQY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

521460:ATHE RS03875
gene id: 521460:ATHE_RS03875
uniprot id: B9MQ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

521460:ATHE RS14535
gene id: 521460:ATHE_RS14535
uniprot id: B9MQF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

521460:ATHE RS02705
gene id: 521460:ATHE_RS02705
uniprot id: B9MPB1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

521460:ATHE RS08455
gene id: 521460:ATHE_RS08455
uniprot id: B9MKC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

521460:ATHE RS04865
gene id: 521460:ATHE_RS04865
uniprot id: B9MQX0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

521460:ATHE RS03110
gene id: 521460:ATHE_RS03110
uniprot id: B9MPI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

521460:ATHE RS03640
gene id: 521460:ATHE_RS03640
uniprot id: B9MQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

521460:ATHE RS10385
gene id: 521460:ATHE_RS10385
uniprot id: B9MLF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS09925
gene id: 521460:ATHE_RS09925
uniprot id: B9ML73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

521460:ATHE RS04145
gene id: 521460:ATHE_RS04145
uniprot id: B9MQI9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

521460:ATHE RS00815
gene id: 521460:ATHE_RS00815
uniprot id: B9MM86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

521460:ATHE RS05315
gene id: 521460:ATHE_RS05315
uniprot id: B9MR59
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

521460:ATHE RS09840
gene id: 521460:ATHE_RS09840
uniprot id: B9ML58
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

521460:ATHE RS04160
gene id: 521460:ATHE_RS04160
uniprot id: B9MQJ2
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

521460:ATHE RS04470
gene id: 521460:ATHE_RS04470
uniprot id: B9MQP6
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS00100
gene id: 521460:ATHE_RS00100
uniprot id: B9MLH9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

521460:ATHE RS09120
gene id: 521460:ATHE_RS09120
uniprot id: B9MKP9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS06155
gene id: 521460:ATHE_RS06155
uniprot id: B9MRM8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521460:ATHE RS08240
gene id: 521460:ATHE_RS08240
uniprot id: B9MK83
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

521460:ATHE RS06685
gene id: 521460:ATHE_RS06685
uniprot id: B9MRY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

521460:ATHE RS01025
gene id: 521460:ATHE_RS01025
uniprot id: B9MMC8
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

521460:ATHE RS02995
gene id: 521460:ATHE_RS02995
uniprot id: B9MPG8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

521460:ATHE RS06025
gene id: 521460:ATHE_RS06025
uniprot id: B9MRK2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

521460:ATHE RS04445
gene id: 521460:ATHE_RS04445
uniprot id: B9MQP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

521460:ATHE RS07000
gene id: 521460:ATHE_RS07000
uniprot id: B9MS47
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

521460:ATHE RS07200
gene id: 521460:ATHE_RS07200
uniprot id: B9MS88
names: Similarity
messages: Belongs to the GARS family.

521460:ATHE RS13315
gene id: 521460:ATHE_RS13315
uniprot id: B9MPS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS08265
gene id: 521460:ATHE_RS08265
uniprot id: B9MK88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

521460:ATHE RS00245
gene id: 521460:ATHE_RS00245
uniprot id: B9MLK5
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS13970
gene id: 521460:ATHE_RS13970
uniprot id: B9MQG1
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

521460:ATHE RS10030
gene id: 521460:ATHE_RS10030
uniprot id: B9ML92
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

521460:ATHE RS05755
gene id: 521460:ATHE_RS05755
uniprot id: B9MRE8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

521460:ATHE RS02735
gene id: 521460:ATHE_RS02735
uniprot id: B9MPB7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

521460:ATHE RS08915
gene id: 521460:ATHE_RS08915
uniprot id: B9MKK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

521460:ATHE RS05145
gene id: 521460:ATHE_RS05145
uniprot id: B9MR26
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

521460:ATHE RS12895
gene id: 521460:ATHE_RS12895
uniprot id: B9MP66
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

521460:ATHE RS06900
gene id: 521460:ATHE_RS06900
uniprot id: B9MS28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

521460:ATHE RS05160
gene id: 521460:ATHE_RS05160
uniprot id: B9MR28
names: Similarity
messages: Belongs to the histone deacetylase family.

521460:ATHE RS10880
gene id: 521460:ATHE_RS10880
uniprot id: B9MM18
names: Similarity
messages: Belongs to the FlgD family.

521460:ATHE RS08515
gene id: 521460:ATHE_RS08515
uniprot id: B9MKD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

521460:ATHE RS02745
gene id: 521460:ATHE_RS02745
uniprot id: B9MPB9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

521460:ATHE RS00925
gene id: 521460:ATHE_RS00925
uniprot id: B9MKB9
names: Similarity
messages: Belongs to the UPF0236 family.

521460:ATHE RS06890
gene id: 521460:ATHE_RS06890
uniprot id: B9MS26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

521460:ATHE RS13410
gene id: 521460:ATHE_RS13410
uniprot id: B9MPT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

521460:ATHE RS13185
gene id: 521460:ATHE_RS13185
uniprot id: B9MPP2
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS08380
gene id: 521460:ATHE_RS08380
uniprot id: B9MKB1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

521460:ATHE RS07225
gene id: 521460:ATHE_RS07225
uniprot id: B9MS93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

521460:ATHE RS01860
gene id: 521460:ATHE_RS01860
uniprot id: B9MN60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

521460:ATHE RS09040
gene id: 521460:ATHE_RS09040
uniprot id: B9MKN3
names: Similarity
messages: Belongs to the peptidase S41A family.

521460:ATHE RS10585
gene id: 521460:ATHE_RS10585
uniprot id: B9MLW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

521460:ATHE RS07105
gene id: 521460:ATHE_RS07105
uniprot id: B9MS69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

521460:ATHE RS07010
gene id: 521460:ATHE_RS07010
uniprot id: B9MS49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Monomer.

521460:ATHE RS07475
gene id: 521460:ATHE_RS07475
uniprot id: B9MJT9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

521460:ATHE RS04450
gene id: 521460:ATHE_RS04450
uniprot id: B9MQP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS01200
gene id: 521460:ATHE_RS01200
uniprot id: B9MMG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

521460:ATHE RS06490
gene id: 521460:ATHE_RS06490
uniprot id: B9MRU4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

521460:ATHE RS01355
gene id: 521460:ATHE_RS01355
uniprot id: B9MMX2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS02895
gene id: 521460:ATHE_RS02895
uniprot id: B9MPE8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS07110
gene id: 521460:ATHE_RS07110
uniprot id: B9MS70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

521460:ATHE RS09580
gene id: 521460:ATHE_RS09580
uniprot id: B9MKZ0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

521460:ATHE RS08175
gene id: 521460:ATHE_RS08175
uniprot id: B9MK70
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

521460:ATHE RS13510
gene id: 521460:ATHE_RS13510
uniprot id: B9MPV5
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

521460:ATHE RS11255
gene id: 521460:ATHE_RS11255
uniprot id: B9MMK8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

521460:ATHE RS08230
gene id: 521460:ATHE_RS08230
uniprot id: B9MK81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

521460:ATHE RS06000
gene id: 521460:ATHE_RS06000
uniprot id: B9MRJ6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

521460:ATHE RS02860
gene id: 521460:ATHE_RS02860
uniprot id: B9MPE1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

521460:ATHE RS00835
gene id: 521460:ATHE_RS00835
uniprot id: B9MM90
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

521460:ATHE RS11150
gene id: 521460:ATHE_RS11150
uniprot id: B9MM66
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

521460:ATHE RS07435
gene id: 521460:ATHE_RS07435
uniprot id: B9MJT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

521460:ATHE RS10470
gene id: 521460:ATHE_RS10470
uniprot id: B9MLH2
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

521460:ATHE RS08225
gene id: 521460:ATHE_RS08225
uniprot id: B9MK80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

521460:ATHE RS04310
gene id: 521460:ATHE_RS04310
uniprot id: B9MQM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

521460:ATHE RS04195
gene id: 521460:ATHE_RS04195
uniprot id: B9MQJ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

521460:ATHE RS00845
gene id: 521460:ATHE_RS00845
uniprot id: B9MM92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

521460:ATHE RS07840
gene id: 521460:ATHE_RS07840
uniprot id: B9MK03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

521460:ATHE RS10630
gene id: 521460:ATHE_RS10630
uniprot id: B9MLW8
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

521460:ATHE RS11340
gene id: 521460:ATHE_RS11340
uniprot id: B9MMM5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

521460:ATHE RS08150
gene id: 521460:ATHE_RS08150
uniprot id: B9MK64
names: Similarity
messages: Belongs to the EamA transporter family.

521460:ATHE RS05445
gene id: 521460:ATHE_RS05445
uniprot id: B9MR85
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

521460:ATHE RS06525
gene id: 521460:ATHE_RS06525
uniprot id: B9MRV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

521460:ATHE RS05750
gene id: 521460:ATHE_RS05750
uniprot id: B9MRE7
names: Similarity
messages: Belongs to the UPF0473 family.

521460:ATHE RS13905
gene id: 521460:ATHE_RS13905
uniprot id: B9MQE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

521460:ATHE RS08685
gene id: 521460:ATHE_RS08685
uniprot id: B9MKG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

521460:ATHE RS04040
gene id: 521460:ATHE_RS04040
uniprot id: B9MQG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

521460:ATHE RS11155
gene id: 521460:ATHE_RS11155
uniprot id: B9MM67
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

521460:ATHE RS08960
gene id: 521460:ATHE_RS08960
uniprot id: B9MKL7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

521460:ATHE RS07020
gene id: 521460:ATHE_RS07020
uniprot id: B9MS51
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

521460:ATHE RS06870
gene id: 521460:ATHE_RS06870
uniprot id: B9MS22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

521460:ATHE RS05655
gene id: 521460:ATHE_RS05655
uniprot id: B9MRC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

521460:ATHE RS06270
gene id: 521460:ATHE_RS06270
uniprot id: B9MRQ1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

521460:ATHE RS07715
gene id: 521460:ATHE_RS07715
uniprot id: B9MJX9
names: Similarity
messages: Belongs to the asparagine synthetase family.

521460:ATHE RS06735
gene id: 521460:ATHE_RS06735
uniprot id: B9MRZ5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

521460:ATHE RS00885
gene id: 521460:ATHE_RS00885
uniprot id: B9MMA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS11705
gene id: 521460:ATHE_RS11705
uniprot id: B9MMU5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

521460:ATHE RS02280
gene id: 521460:ATHE_RS02280
uniprot id: B9MNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

521460:ATHE RS05245
gene id: 521460:ATHE_RS05245
uniprot id: B9MR45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

521460:ATHE RS09570
gene id: 521460:ATHE_RS09570
uniprot id: B9MKY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

521460:ATHE RS06545
gene id: 521460:ATHE_RS06545
uniprot id: B9MRV5
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

521460:ATHE RS12255
gene id: 521460:ATHE_RS12255
uniprot id: B9MNG9
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

521460:ATHE RS09130
gene id: 521460:ATHE_RS09130
uniprot id: B9MKQ1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

521460:ATHE RS05815
gene id: 521460:ATHE_RS05815
uniprot id: B9MRG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

521460:ATHE RS04930
gene id: 521460:ATHE_RS04930
uniprot id: B9MQY2
names: Similarity
messages: Belongs to the CinA family.

521460:ATHE RS03120
gene id: 521460:ATHE_RS03120
uniprot id: B9MPJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

521460:ATHE RS01015
gene id: 521460:ATHE_RS01015
uniprot id: B9MMC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521460:ATHE RS12510
gene id: 521460:ATHE_RS12510
uniprot id: B9MNY8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

521460:ATHE RS00220
gene id: 521460:ATHE_RS00220
uniprot id: B9MLK2
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS08090
gene id: 521460:ATHE_RS08090
uniprot id: B9MK51
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

521460:ATHE RS04420
gene id: 521460:ATHE_RS04420
uniprot id: B9MQN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

521460:ATHE RS01765
gene id: 521460:ATHE_RS01765
uniprot id: B9MN44
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

521460:ATHE RS05975
gene id: 521460:ATHE_RS05975
uniprot id: B9MRJ1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

521460:ATHE RS06930
gene id: 521460:ATHE_RS06930
uniprot id: B9MS34
names: Similarity
messages: Belongs to the leucine-binding protein family.

521460:ATHE RS01745
gene id: 521460:ATHE_RS01745
uniprot id: B9MN40
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

521460:ATHE RS04680
gene id: 521460:ATHE_RS04680
uniprot id: B9MQT5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

521460:ATHE RS05950
gene id: 521460:ATHE_RS05950
uniprot id: B9MRI6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

521460:ATHE RS01885
gene id: 521460:ATHE_RS01885
uniprot id: B9MN66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

521460:ATHE RS04475
gene id: 521460:ATHE_RS04475
uniprot id: B9MQP7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

521460:ATHE RS05090
gene id: 521460:ATHE_RS05090
uniprot id: B9MR14
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

521460:ATHE RS12695
gene id: 521460:ATHE_RS12695
uniprot id: B9MP28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

521460:ATHE RS03255
gene id: 521460:ATHE_RS03255
uniprot id: B9MPL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

521460:ATHE RS06865
gene id: 521460:ATHE_RS06865
uniprot id: B9MS21
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

521460:ATHE RS07400
gene id: 521460:ATHE_RS07400
uniprot id: B9MJS4
names: Similarity
messages: Belongs to the UPF0111 family.

521460:ATHE RS06335
gene id: 521460:ATHE_RS06335
uniprot id: B9MRR4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

521460:ATHE RS13770
gene id: 521460:ATHE_RS13770
uniprot id: B9MPZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

521460:ATHE RS07755
gene id: 521460:ATHE_RS07755
uniprot id: B9MJY7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

521460:ATHE RS03085
gene id: 521460:ATHE_RS03085
uniprot id: Q44407
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PGI/PMI family.
messages: Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency.
messages: Homodimer.

521460:ATHE RS02840
gene id: 521460:ATHE_RS02840
uniprot id: B9MPD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

521460:ATHE RS07405
gene id: 521460:ATHE_RS07405
uniprot id: B9MJS5
names: Subcellular Location Annotation
messages: Membrane

521460:ATHE RS12875
gene id: 521460:ATHE_RS12875
uniprot id: B9MP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521460:ATHE RS04255
gene id: 521460:ATHE_RS04255
uniprot id: B9MQL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane