521098:AACI RS06680
gene id: 521098:AACI_RS06680
uniprot id: C8WWA4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

521098:AACI RS06985
gene id: 521098:AACI_RS06985
uniprot id: C8WWG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

521098:AACI RS13800
gene id: 521098:AACI_RS13800
uniprot id: C8WUH0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS05430
gene id: 521098:AACI_RS05430
uniprot id: C8WVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

521098:AACI RS00915
gene id: 521098:AACI_RS00915
uniprot id: C8WQR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

521098:AACI RS00510
gene id: 521098:AACI_RS00510
uniprot id: C8WQ56
names: Similarity
messages: Belongs to the RuBisCO large chain family.

521098:AACI RS07695
gene id: 521098:AACI_RS07695
uniprot id: C8WWV4
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS07660
gene id: 521098:AACI_RS07660
uniprot id: C8WWU7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

521098:AACI RS14855
gene id: 521098:AACI_RS14855
uniprot id: C8WYB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm

521098:AACI RS00375
gene id: 521098:AACI_RS00375
uniprot id: C8WQ30
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS14300
gene id: 521098:AACI_RS14300
uniprot id: C8WV52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

521098:AACI RS04430
gene id: 521098:AACI_RS04430
uniprot id: C8WUT8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

521098:AACI RS00235
gene id: 521098:AACI_RS00235
uniprot id: C8WQ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

521098:AACI RS13575
gene id: 521098:AACI_RS13575
uniprot id: C8WTZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

521098:AACI RS02640
gene id: 521098:AACI_RS02640
uniprot id: C8WSR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

521098:AACI RS05550
gene id: 521098:AACI_RS05550
uniprot id: C8WVM7
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

521098:AACI RS05985
gene id: 521098:AACI_RS05985
uniprot id: C8WVW8
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS13400
gene id: 521098:AACI_RS13400
uniprot id: C8WTW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

521098:AACI RS01615
gene id: 521098:AACI_RS01615
uniprot id: C8WRF3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

521098:AACI RS13405
gene id: 521098:AACI_RS13405
uniprot id: C8WTW5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

521098:AACI RS02330
gene id: 521098:AACI_RS02330
uniprot id: C8WS68
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS13675
gene id: 521098:AACI_RS13675
uniprot id: C8WU19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

521098:AACI RS04940
gene id: 521098:AACI_RS04940
uniprot id: C8WV39
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

521098:AACI RS02095
gene id: 521098:AACI_RS02095
uniprot id: C8WS23
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

521098:AACI RS04580
gene id: 521098:AACI_RS04580
uniprot id: C8WUW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

521098:AACI RS09885
gene id: 521098:AACI_RS09885
uniprot id: C8WY52
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS06925
gene id: 521098:AACI_RS06925
uniprot id: C8WWF2
names: Similarity
messages: Belongs to the FlgD family.

521098:AACI RS03285
gene id: 521098:AACI_RS03285
uniprot id: C8WTF4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS05210
gene id: 521098:AACI_RS05210
uniprot id: C8WVG1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

521098:AACI RS13480
gene id: 521098:AACI_RS13480
uniprot id: C8WTY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

521098:AACI RS14100
gene id: 521098:AACI_RS14100
uniprot id: C8WUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

521098:AACI RS13690
gene id: 521098:AACI_RS13690
uniprot id: C8WUE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

521098:AACI RS15165
gene id: 521098:AACI_RS15165
uniprot id: C8WYI2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

521098:AACI RS11025
gene id: 521098:AACI_RS11025
uniprot id: C8WR66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS13975
gene id: 521098:AACI_RS13975
uniprot id: C8WUK6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

521098:AACI RS12440
gene id: 521098:AACI_RS12440
uniprot id: C8WT09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

521098:AACI RS14450
gene id: 521098:AACI_RS14450
uniprot id: C8WV80
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS04990
gene id: 521098:AACI_RS04990
uniprot id: C8WVB7
names: Similarity
messages: Belongs to the peptidase M24B family.

521098:AACI RS12105
gene id: 521098:AACI_RS12105
uniprot id: C8WSH2
names: Similarity
messages: Belongs to the acyltransferase 3 family.

521098:AACI RS12730
gene id: 521098:AACI_RS12730
uniprot id: C8WT65
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

521098:AACI RS02205
gene id: 521098:AACI_RS02205
uniprot id: C8WS42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

521098:AACI RS13060
gene id: 521098:AACI_RS13060
uniprot id: C8WTP6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

521098:AACI RS14045
gene id: 521098:AACI_RS14045
uniprot id: C8WUM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

521098:AACI RS08235
gene id: 521098:AACI_RS08235
uniprot id: C8WX63
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS06250
gene id: 521098:AACI_RS06250
uniprot id: C8WW18
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

521098:AACI RS04780
gene id: 521098:AACI_RS04780
uniprot id: C8WV08
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

521098:AACI RS01745
gene id: 521098:AACI_RS01745
uniprot id: C8WRH9
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS13140
gene id: 521098:AACI_RS13140
uniprot id: C8WTR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

521098:AACI RS03480
gene id: 521098:AACI_RS03480
uniprot id: C8WTJ4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

521098:AACI RS10275
gene id: 521098:AACI_RS10275
uniprot id: C8WQE6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

521098:AACI RS08095
gene id: 521098:AACI_RS08095
uniprot id: C8WX35
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS09845
gene id: 521098:AACI_RS09845
uniprot id: C8WY43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

521098:AACI RS07380
gene id: 521098:AACI_RS07380
uniprot id: C8WWP3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521098:AACI RS08855
gene id: 521098:AACI_RS08855
uniprot id: C8WXI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

521098:AACI RS08325
gene id: 521098:AACI_RS08325
uniprot id: C8WX83
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

521098:AACI RS10610
gene id: 521098:AACI_RS10610
uniprot id: C8WQY9
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

521098:AACI RS10970
gene id: 521098:AACI_RS10970
uniprot id: C8WR55
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS00030
gene id: 521098:AACI_RS00030
uniprot id: C8WXT1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

521098:AACI RS06630
gene id: 521098:AACI_RS06630
uniprot id: C8WW93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

521098:AACI RS09340
gene id: 521098:AACI_RS09340
uniprot id: C8WXU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

521098:AACI RS02755
gene id: 521098:AACI_RS02755
uniprot id: C8WST4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

521098:AACI RS06220
gene id: 521098:AACI_RS06220
uniprot id: C8WW12
names: Similarity
messages: Belongs to the UPF0473 family.

521098:AACI RS10505
gene id: 521098:AACI_RS10505
uniprot id: C8WQJ1
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS04730
gene id: 521098:AACI_RS04730
uniprot id: C8WUZ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

521098:AACI RS11400
gene id: 521098:AACI_RS11400
uniprot id: C8WRQ2
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

521098:AACI RS14455
gene id: 521098:AACI_RS14455
uniprot id: C8WV81
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

521098:AACI RS07280
gene id: 521098:AACI_RS07280
uniprot id: C8WWM3
names: Similarity
messages: Belongs to the UPF0234 family.

521098:AACI RS07525
gene id: 521098:AACI_RS07525
uniprot id: C8WWS0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

521098:AACI RS02105
gene id: 521098:AACI_RS02105
uniprot id: C8WS25
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

521098:AACI RS07225
gene id: 521098:AACI_RS07225
uniprot id: C8WWL2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

521098:AACI RS13955
gene id: 521098:AACI_RS13955
uniprot id: C8WUK2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

521098:AACI RS00365
gene id: 521098:AACI_RS00365
uniprot id: C8WQ28
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS03995
gene id: 521098:AACI_RS03995
uniprot id: C8WU78
names: Similarity
messages: Belongs to the citrate synthase family.

521098:AACI RS09190
gene id: 521098:AACI_RS09190
uniprot id: C8WXQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

521098:AACI RS13635
gene id: 521098:AACI_RS13635
uniprot id: C8WU11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

521098:AACI RS07090
gene id: 521098:AACI_RS07090
uniprot id: C8WWI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521098:AACI RS13630
gene id: 521098:AACI_RS13630
uniprot id: C8WU10
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

521098:AACI RS08090
gene id: 521098:AACI_RS08090
uniprot id: C8WX33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

521098:AACI RS06510
gene id: 521098:AACI_RS06510
uniprot id: C8WW69
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

521098:AACI RS06255
gene id: 521098:AACI_RS06255
uniprot id: C8WW19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

521098:AACI RS01015
gene id: 521098:AACI_RS01015
uniprot id: C8WQT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS04700
gene id: 521098:AACI_RS04700
uniprot id: C8WUZ2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

521098:AACI RS07075
gene id: 521098:AACI_RS07075
uniprot id: C8WWI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

521098:AACI RS13935
gene id: 521098:AACI_RS13935
uniprot id: C8WUJ8
names: Similarity
messages: Belongs to the UPF0045 family.

521098:AACI RS11595
gene id: 521098:AACI_RS11595
uniprot id: C8WRU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

521098:AACI RS03700
gene id: 521098:AACI_RS03700
uniprot id: C8WTN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

521098:AACI RS11720
gene id: 521098:AACI_RS11720
uniprot id: C8WRW6
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

521098:AACI RS10750
gene id: 521098:AACI_RS10750
uniprot id: C8WR17
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

521098:AACI RS09495
gene id: 521098:AACI_RS09495
uniprot id: C8WXX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

521098:AACI RS11845
gene id: 521098:AACI_RS11845
uniprot id: C8WSB7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521098:AACI RS06650
gene id: 521098:AACI_RS06650
uniprot id: C8WW98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

521098:AACI RS09900
gene id: 521098:AACI_RS09900
uniprot id: C8WY55
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

521098:AACI RS10770
gene id: 521098:AACI_RS10770
uniprot id: C8WR21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS09295
gene id: 521098:AACI_RS09295
uniprot id: C8WXS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

521098:AACI RS06705
gene id: 521098:AACI_RS06705
uniprot id: C8WWA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

521098:AACI RS14615
gene id: 521098:AACI_RS14615
uniprot id: C8WVB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

521098:AACI RS14160
gene id: 521098:AACI_RS14160
uniprot id: C8WUP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS10070
gene id: 521098:AACI_RS10070
uniprot id: C8WQA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS13995
gene id: 521098:AACI_RS13995
uniprot id: C8WUL0
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS01610
gene id: 521098:AACI_RS01610
uniprot id: C8WRF2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

521098:AACI RS06845
gene id: 521098:AACI_RS06845
uniprot id: C8WWD6
names: Similarity
messages: Belongs to the MYG1 family.

521098:AACI RS13355
gene id: 521098:AACI_RS13355
uniprot id: C8WTV5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

521098:AACI RS06305
gene id: 521098:AACI_RS06305
uniprot id: C8WW29
names: Similarity
messages: Belongs to the transpeptidase family.

521098:AACI RS06410
gene id: 521098:AACI_RS06410
uniprot id: C8WW49
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

521098:AACI RS06950
gene id: 521098:AACI_RS06950
uniprot id: C8WWF8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

521098:AACI RS09040
gene id: 521098:AACI_RS09040
uniprot id: C8WXM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

521098:AACI RS13465
gene id: 521098:AACI_RS13465
uniprot id: C8WTX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

521098:AACI RS13010
gene id: 521098:AACI_RS13010
uniprot id: C8WTB4
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS02085
gene id: 521098:AACI_RS02085
uniprot id: C8WS21
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

521098:AACI RS14090
gene id: 521098:AACI_RS14090
uniprot id: C8WUN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

521098:AACI RS06980
gene id: 521098:AACI_RS06980
uniprot id: C8WWG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

521098:AACI RS06320
gene id: 521098:AACI_RS06320
uniprot id: C8WW32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

521098:AACI RS06830
gene id: 521098:AACI_RS06830
uniprot id: C8WWD3
names: Similarity
messages: Belongs to the DprA/Smf family.

521098:AACI RS08475
gene id: 521098:AACI_RS08475
uniprot id: C8WXA9
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS12965
gene id: 521098:AACI_RS12965
uniprot id: C8WTA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

521098:AACI RS15350
gene id: 521098:AACI_RS15350
uniprot id: C8WYM2
names: Similarity
messages: Belongs to the GSP E family.

521098:AACI RS04685
gene id: 521098:AACI_RS04685
uniprot id: C8WUY9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

521098:AACI RS11160
gene id: 521098:AACI_RS11160
uniprot id: C8WR96
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS04495
gene id: 521098:AACI_RS04495
uniprot id: C8WUV1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

521098:AACI RS12235
gene id: 521098:AACI_RS12235
uniprot id: C8WSJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

521098:AACI RS06180
gene id: 521098:AACI_RS06180
uniprot id: C8WW04
names: Similarity
messages: Belongs to the thioredoxin family.

521098:AACI RS02295
gene id: 521098:AACI_RS02295
uniprot id: C8WS60
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

521098:AACI RS06290
gene id: 521098:AACI_RS06290
uniprot id: C8WW26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

521098:AACI RS05095
gene id: 521098:AACI_RS05095
uniprot id: C8WVD8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

521098:AACI RS11980
gene id: 521098:AACI_RS11980
uniprot id: C8WSE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

521098:AACI RS09750
gene id: 521098:AACI_RS09750
uniprot id: C8WY23
names: Similarity
messages: Belongs to the arginase family.

521098:AACI RS11055
gene id: 521098:AACI_RS11055
uniprot id: C8WR73
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

521098:AACI RS00810
gene id: 521098:AACI_RS00810
uniprot id: C8WQP4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521098:AACI RS14335
gene id: 521098:AACI_RS14335
uniprot id: C8WV58
names: Activity Regulation
names: Biotechnology
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.
messages: Ca(2+), Mg(2+) and EDTA have little effect on enzyme activity at 1-10 mM. Zn(2+) at 3, 5, 7 or 10 mM inhibits activity by 20%, 30%, 40% and 65%, respectively.
messages: Has potential use in hydrolyzing lactose in neutral pH dairy products such as whole milk or whey. Also could be used in milk lactose hydrolysis during pasteurization at high temperatures.
messages: Hydrolyzes o-nitrophenyl-beta-D-galactopyranoside (ONPG) and p-nitrophenyl-beta-D-fucopyranoside (PNPF), but not p-nitrophenyl-beta-D-glucopyranoside (PNPG), p-nitrophenyl-beta-D-xylopyranoside (PNPX) or p-nitrophenyl-beta-D-arabinopyranoside (PNPA). Also hydrolyzes lactose, including lactose in milk.

521098:AACI RS13365
gene id: 521098:AACI_RS13365
uniprot id: C8WTV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

521098:AACI RS08750
gene id: 521098:AACI_RS08750
uniprot id: C8WXG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

521098:AACI RS03680
gene id: 521098:AACI_RS03680
uniprot id: C8WTN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

521098:AACI RS06285
gene id: 521098:AACI_RS06285
uniprot id: C8WW25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

521098:AACI RS08525
gene id: 521098:AACI_RS08525
uniprot id: C8WXC0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

521098:AACI RS09060
gene id: 521098:AACI_RS09060
uniprot id: C8WXN1
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

521098:AACI RS11515
gene id: 521098:AACI_RS11515
uniprot id: C8WRS5
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS08355
gene id: 521098:AACI_RS08355
uniprot id: C8WX88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

521098:AACI RS11015
gene id: 521098:AACI_RS11015
uniprot id: C8WR64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

521098:AACI RS09315
gene id: 521098:AACI_RS09315
uniprot id: C8WXT7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

521098:AACI RS02380
gene id: 521098:AACI_RS02380
uniprot id: C8WS78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

521098:AACI RS04635
gene id: 521098:AACI_RS04635
uniprot id: C8WUX8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

521098:AACI RS00585
gene id: 521098:AACI_RS00585
uniprot id: C8WQ72
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

521098:AACI RS12320
gene id: 521098:AACI_RS12320
uniprot id: C8WSL5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

521098:AACI RS10190
gene id: 521098:AACI_RS10190
uniprot id: C8WQC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

521098:AACI RS15445
gene id: 521098:AACI_RS15445
uniprot id: C8WYP3
names: Similarity
messages: Belongs to the GSP E family.

521098:AACI RS03145
gene id: 521098:AACI_RS03145
uniprot id: C8WTC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

521098:AACI RS09375
gene id: 521098:AACI_RS09375
uniprot id: C8WXU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS10265
gene id: 521098:AACI_RS10265
uniprot id: C8WQE4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

521098:AACI RS09330
gene id: 521098:AACI_RS09330
uniprot id: C8WXU0
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS06270
gene id: 521098:AACI_RS06270
uniprot id: C8WW22
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

521098:AACI RS06545
gene id: 521098:AACI_RS06545
uniprot id: C8WW76
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

521098:AACI RS08950
gene id: 521098:AACI_RS08950
uniprot id: C8WXK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

521098:AACI RS07095
gene id: 521098:AACI_RS07095
uniprot id: C8WWI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

521098:AACI RS10685
gene id: 521098:AACI_RS10685
uniprot id: C8WR04
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS06045
gene id: 521098:AACI_RS06045
uniprot id: C8WVX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

521098:AACI RS04420
gene id: 521098:AACI_RS04420
uniprot id: C8WUT6
names: Similarity
messages: Belongs to the thioredoxin family.

521098:AACI RS01865
gene id: 521098:AACI_RS01865
uniprot id: C8WRK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

521098:AACI RS11190
gene id: 521098:AACI_RS11190
uniprot id: C8WRL0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

521098:AACI RS06655
gene id: 521098:AACI_RS06655
uniprot id: C8WW99
names: Similarity
messages: Belongs to the fabD family.

521098:AACI RS08245
gene id: 521098:AACI_RS08245
uniprot id: C8WX65
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

521098:AACI RS09235
gene id: 521098:AACI_RS09235
uniprot id: C8WXR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

521098:AACI RS13175
gene id: 521098:AACI_RS13175
uniprot id: C8WTR9
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

521098:AACI RS01700
gene id: 521098:AACI_RS01700
uniprot id: C8WRH0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

521098:AACI RS07130
gene id: 521098:AACI_RS07130
uniprot id: C8WWJ3
names: Similarity
messages: Belongs to the ribF family.

521098:AACI RS09480
gene id: 521098:AACI_RS09480
uniprot id: C8WXX0
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

521098:AACI RS07740
gene id: 521098:AACI_RS07740
uniprot id: C8WWW3
names: Similarity
messages: Belongs to the glutamine synthetase family.

521098:AACI RS15120
gene id: 521098:AACI_RS15120
uniprot id: C8WYH4
names: Similarity
messages: Belongs to the GerABKA family.

521098:AACI RS03745
gene id: 521098:AACI_RS03745
uniprot id: C8WU27
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS00070
gene id: 521098:AACI_RS00070
uniprot id: C8WPX2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

521098:AACI RS07285
gene id: 521098:AACI_RS07285
uniprot id: C8WWM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

521098:AACI RS05565
gene id: 521098:AACI_RS05565
uniprot id: C8WVN0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

521098:AACI RS03875
gene id: 521098:AACI_RS03875
uniprot id: C8WU53
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS03470
gene id: 521098:AACI_RS03470
uniprot id: C8WTJ2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

521098:AACI RS06090
gene id: 521098:AACI_RS06090
uniprot id: C8WVY8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

521098:AACI RS02110
gene id: 521098:AACI_RS02110
uniprot id: C8WS26
names: Similarity
messages: Belongs to the GARS family.

521098:AACI RS03345
gene id: 521098:AACI_RS03345
uniprot id: C8WTG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

521098:AACI RS13135
gene id: 521098:AACI_RS13135
uniprot id: C8WTR1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

521098:AACI RS10115
gene id: 521098:AACI_RS10115
uniprot id: C8WQB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS11035
gene id: 521098:AACI_RS11035
uniprot id: C8WR68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

521098:AACI RS08170
gene id: 521098:AACI_RS08170
uniprot id: C8WX50
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

521098:AACI RS05865
gene id: 521098:AACI_RS05865
uniprot id: C8WVU2
names: Subunit
messages: Homodimer.

521098:AACI RS12115
gene id: 521098:AACI_RS12115
uniprot id: C8WSH4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

521098:AACI RS10440
gene id: 521098:AACI_RS10440
uniprot id: C8WQH8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

521098:AACI RS00170
gene id: 521098:AACI_RS00170
uniprot id: C8WPY9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS10550
gene id: 521098:AACI_RS10550
uniprot id: C8WQK1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

521098:AACI RS10130
gene id: 521098:AACI_RS10130
uniprot id: C8WQB8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

521098:AACI RS15100
gene id: 521098:AACI_RS15100
uniprot id: C8WYH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

521098:AACI RS12510
gene id: 521098:AACI_RS12510
uniprot id: C8WT23
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

521098:AACI RS09175
gene id: 521098:AACI_RS09175
uniprot id: C8WXQ2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

521098:AACI RS00085
gene id: 521098:AACI_RS00085
uniprot id: C8WPX5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS12855
gene id: 521098:AACI_RS12855
uniprot id: C8WT83
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS10525
gene id: 521098:AACI_RS10525
uniprot id: C8WQJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

521098:AACI RS11480
gene id: 521098:AACI_RS11480
uniprot id: C8WRR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

521098:AACI RS11610
gene id: 521098:AACI_RS11610
uniprot id: C8WRU3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

521098:AACI RS13370
gene id: 521098:AACI_RS13370
uniprot id: C8WTV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

521098:AACI RS14315
gene id: 521098:AACI_RS14315
uniprot id: C8WV55
names: Similarity
messages: Belongs to the universal stress protein A family.

521098:AACI RS04080
gene id: 521098:AACI_RS04080
uniprot id: C8WU94
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

521098:AACI RS15400
gene id: 521098:AACI_RS15400
uniprot id: C8WWR3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

521098:AACI RS02740
gene id: 521098:AACI_RS02740
uniprot id: C8WST1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

521098:AACI RS10590
gene id: 521098:AACI_RS10590
uniprot id: C8WQY5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

521098:AACI RS14050
gene id: 521098:AACI_RS14050
uniprot id: C8WUM1
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

521098:AACI RS04630
gene id: 521098:AACI_RS04630
uniprot id: C8WUX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

521098:AACI RS13410
gene id: 521098:AACI_RS13410
uniprot id: C8WTW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

521098:AACI RS11030
gene id: 521098:AACI_RS11030
uniprot id: C8WR67
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

521098:AACI RS12920
gene id: 521098:AACI_RS12920
uniprot id: C8WT96
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

521098:AACI RS07690
gene id: 521098:AACI_RS07690
uniprot id: C8WWV3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

521098:AACI RS11330
gene id: 521098:AACI_RS11330
uniprot id: C8WRN8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

521098:AACI RS06595
gene id: 521098:AACI_RS06595
uniprot id: C8WW85
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

521098:AACI RS06600
gene id: 521098:AACI_RS06600
uniprot id: C8WW86
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

521098:AACI RS06365
gene id: 521098:AACI_RS06365
uniprot id: C8WW40
names: Similarity
messages: Belongs to the UPF0749 family.

521098:AACI RS10495
gene id: 521098:AACI_RS10495
uniprot id: C8WQI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

521098:AACI RS09695
gene id: 521098:AACI_RS09695
uniprot id: C8WY13
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

521098:AACI RS10230
gene id: 521098:AACI_RS10230
uniprot id: C8WQD7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

521098:AACI RS09380
gene id: 521098:AACI_RS09380
uniprot id: C8WXU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS09485
gene id: 521098:AACI_RS09485
uniprot id: C8WXX1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS09260
gene id: 521098:AACI_RS09260
uniprot id: C8WXR6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

521098:AACI RS10315
gene id: 521098:AACI_RS10315
uniprot id: C8WQF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS06310
gene id: 521098:AACI_RS06310
uniprot id: C8WW30
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS08555
gene id: 521098:AACI_RS08555
uniprot id: C8WXC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

521098:AACI RS08220
gene id: 521098:AACI_RS08220
uniprot id: C8WX60
names: Similarity
messages: Belongs to the TrpC family.

521098:AACI RS04170
gene id: 521098:AACI_RS04170
uniprot id: C8WUB3
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS05070
gene id: 521098:AACI_RS05070
uniprot id: C8WVD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

521098:AACI RS04975
gene id: 521098:AACI_RS04975
uniprot id: C8WV46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

521098:AACI RS03760
gene id: 521098:AACI_RS03760
uniprot id: C8WU30
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

521098:AACI RS12445
gene id: 521098:AACI_RS12445
uniprot id: C8WT10
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

521098:AACI RS12015
gene id: 521098:AACI_RS12015
uniprot id: C8WSF4
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

521098:AACI RS08985
gene id: 521098:AACI_RS08985
uniprot id: C8WXL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

521098:AACI RS11245
gene id: 521098:AACI_RS11245
uniprot id: C8WRM1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

521098:AACI RS05545
gene id: 521098:AACI_RS05545
uniprot id: C8WVM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

521098:AACI RS13605
gene id: 521098:AACI_RS13605
uniprot id: C8WU05
names: Similarity
messages: Belongs to the CtsR family.

521098:AACI RS10160
gene id: 521098:AACI_RS10160
uniprot id: C8WQC2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521098:AACI RS04240
gene id: 521098:AACI_RS04240
uniprot id: C8WUC8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

521098:AACI RS03035
gene id: 521098:AACI_RS03035
uniprot id: C8WSZ0
names: Subcellular Location Annotation
messages: Cell membrane

521098:AACI RS07750
gene id: 521098:AACI_RS07750
uniprot id: C8WWW5
names: Similarity
messages: Belongs to the UxaA family.

521098:AACI RS12460
gene id: 521098:AACI_RS12460
uniprot id: C8WT13
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS01470
gene id: 521098:AACI_RS01470
uniprot id: C8WRC8
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS13555
gene id: 521098:AACI_RS13555
uniprot id: C8WTZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521098:AACI RS06850
gene id: 521098:AACI_RS06850
uniprot id: C8WWD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

521098:AACI RS06890
gene id: 521098:AACI_RS06890
uniprot id: C8WWE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

521098:AACI RS12420
gene id: 521098:AACI_RS12420
uniprot id: C8WT05
names: Subcellular Location Annotation
messages: Cell membrane

521098:AACI RS00900
gene id: 521098:AACI_RS00900
uniprot id: C8WQR1
names: Similarity
messages: Belongs to the RutC family.

521098:AACI RS01345
gene id: 521098:AACI_RS01345
uniprot id: C8WRC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS12660
gene id: 521098:AACI_RS12660
uniprot id: C8WT50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

521098:AACI RS12725
gene id: 521098:AACI_RS12725
uniprot id: C8WT64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

521098:AACI RS02170
gene id: 521098:AACI_RS02170
uniprot id: C8WS35
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

521098:AACI RS06750
gene id: 521098:AACI_RS06750
uniprot id: C8WWB5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

521098:AACI RS04750
gene id: 521098:AACI_RS04750
uniprot id: C8WV02
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

521098:AACI RS09085
gene id: 521098:AACI_RS09085
uniprot id: C8WXN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

521098:AACI RS10085
gene id: 521098:AACI_RS10085
uniprot id: C8WQA9
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS06530
gene id: 521098:AACI_RS06530
uniprot id: C8WW73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

521098:AACI RS10120
gene id: 521098:AACI_RS10120
uniprot id: C8WQB6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

521098:AACI RS11970
gene id: 521098:AACI_RS11970
uniprot id: C8WSE4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

521098:AACI RS07850
gene id: 521098:AACI_RS07850
uniprot id: C8WWY5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

521098:AACI RS14345
gene id: 521098:AACI_RS14345
uniprot id: C8WV60
names: Similarity
messages: Belongs to the P(II) protein family.

521098:AACI RS12355
gene id: 521098:AACI_RS12355
uniprot id: C8WSM2
names: Similarity
messages: Belongs to the peptidase C56 family.

521098:AACI RS00075
gene id: 521098:AACI_RS00075
uniprot id: C8WPX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

521098:AACI RS09535
gene id: 521098:AACI_RS09535
uniprot id: C8WXY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

521098:AACI RS01780
gene id: 521098:AACI_RS01780
uniprot id: C8WRI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

521098:AACI RS03720
gene id: 521098:AACI_RS03720
uniprot id: C8WU22
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521098:AACI RS04625
gene id: 521098:AACI_RS04625
uniprot id: C8WUX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

521098:AACI RS10955
gene id: 521098:AACI_RS10955
uniprot id: C8WR52
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS02765
gene id: 521098:AACI_RS02765
uniprot id: C8WST6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

521098:AACI RS08730
gene id: 521098:AACI_RS08730
uniprot id: C8WXG3
names: Similarity
messages: Belongs to the TlyA family.

521098:AACI RS05220
gene id: 521098:AACI_RS05220
uniprot id: C8WVG3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

521098:AACI RS03310
gene id: 521098:AACI_RS03310
uniprot id: C8WTF9
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS09105
gene id: 521098:AACI_RS09105
uniprot id: C8WXN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

521098:AACI RS04185
gene id: 521098:AACI_RS04185
uniprot id: C8WUB6
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS08785
gene id: 521098:AACI_RS08785
uniprot id: C8WXH4
names: Similarity
messages: Belongs to the asp23 family.

521098:AACI RS12200
gene id: 521098:AACI_RS12200
uniprot id: C8WSJ1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

521098:AACI RS00565
gene id: 521098:AACI_RS00565
uniprot id: C8WQ68
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

521098:AACI RS05755
gene id: 521098:AACI_RS05755
uniprot id: C8WVS1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

521098:AACI RS03755
gene id: 521098:AACI_RS03755
uniprot id: C8WU29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

521098:AACI RS12325
gene id: 521098:AACI_RS12325
uniprot id: C8WSL6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS07230
gene id: 521098:AACI_RS07230
uniprot id: C8WWL3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

521098:AACI RS12270
gene id: 521098:AACI_RS12270
uniprot id: C8WSK5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS13550
gene id: 521098:AACI_RS13550
uniprot id: C8WTZ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

521098:AACI RS08135
gene id: 521098:AACI_RS08135
uniprot id: C8WX43
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

521098:AACI RS14525
gene id: 521098:AACI_RS14525
uniprot id: C8WV96
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

521098:AACI RS11945
gene id: 521098:AACI_RS11945
uniprot id: C8WSD9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

521098:AACI RS13880
gene id: 521098:AACI_RS13880
uniprot id: C8WUI6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

521098:AACI RS01735
gene id: 521098:AACI_RS01735
uniprot id: C8WRH7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

521098:AACI RS01245
gene id: 521098:AACI_RS01245
uniprot id: C8WQX8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

521098:AACI RS03975
gene id: 521098:AACI_RS03975
uniprot id: C8WU74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS13285
gene id: 521098:AACI_RS13285
uniprot id: C8WTU1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

521098:AACI RS04010
gene id: 521098:AACI_RS04010
uniprot id: C8WU81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

521098:AACI RS11340
gene id: 521098:AACI_RS11340
uniprot id: C8WRP0
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

521098:AACI RS14440
gene id: 521098:AACI_RS14440
uniprot id: C8WV79
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

521098:AACI RS09120
gene id: 521098:AACI_RS09120
uniprot id: C8WXP1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521098:AACI RS09395
gene id: 521098:AACI_RS09395
uniprot id: C8WXV2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

521098:AACI RS12975
gene id: 521098:AACI_RS12975
uniprot id: C8WTA7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

521098:AACI RS04910
gene id: 521098:AACI_RS04910
uniprot id: C8WV33
names: Similarity
messages: Belongs to the AlaDH/PNT family.

521098:AACI RS04125
gene id: 521098:AACI_RS04125
uniprot id: C8WUA3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

521098:AACI RS14235
gene id: 521098:AACI_RS14235
uniprot id: C8WUQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS02315
gene id: 521098:AACI_RS02315
uniprot id: C8WS64
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

521098:AACI RS09855
gene id: 521098:AACI_RS09855
uniprot id: C8WY45
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

521098:AACI RS03650
gene id: 521098:AACI_RS03650
uniprot id: C8WTM9
names: Similarity
messages: Belongs to the acyltransferase 3 family.

521098:AACI RS05275
gene id: 521098:AACI_RS05275
uniprot id: C8WVH2
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS06245
gene id: 521098:AACI_RS06245
uniprot id: C8WW17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

521098:AACI RS08485
gene id: 521098:AACI_RS08485
uniprot id: C8WXB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors.
messages: Membrane

521098:AACI RS06915
gene id: 521098:AACI_RS06915
uniprot id: C8WWF0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

521098:AACI RS09215
gene id: 521098:AACI_RS09215
uniprot id: C8WXQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

521098:AACI RS06745
gene id: 521098:AACI_RS06745
uniprot id: C8WWB4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

521098:AACI RS13375
gene id: 521098:AACI_RS13375
uniprot id: C8WTV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

521098:AACI RS10800
gene id: 521098:AACI_RS10800
uniprot id: C8WR26
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

521098:AACI RS09595
gene id: 521098:AACI_RS09595
uniprot id: C8WXZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

521098:AACI RS08975
gene id: 521098:AACI_RS08975
uniprot id: C8WXL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

521098:AACI RS12465
gene id: 521098:AACI_RS12465
uniprot id: C8WT14
names: Cofactor
messages: Binds 1 FAD per subunit.

521098:AACI RS01155
gene id: 521098:AACI_RS01155
uniprot id: C8WQW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

521098:AACI RS06820
gene id: 521098:AACI_RS06820
uniprot id: C8WWD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

521098:AACI RS14935
gene id: 521098:AACI_RS14935
uniprot id: C8WYD4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

521098:AACI RS06475
gene id: 521098:AACI_RS06475
uniprot id: C8WW62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

521098:AACI RS00895
gene id: 521098:AACI_RS00895
uniprot id: C8WQR0
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

521098:AACI RS01330
gene id: 521098:AACI_RS01330
uniprot id: C8WRB8
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS05560
gene id: 521098:AACI_RS05560
uniprot id: C8WVM9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

521098:AACI RS12275
gene id: 521098:AACI_RS12275
uniprot id: C8WSK6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

521098:AACI RS01255
gene id: 521098:AACI_RS01255
uniprot id: C8WRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

521098:AACI RS09045
gene id: 521098:AACI_RS09045
uniprot id: C8WXM8
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

521098:AACI RS13485
gene id: 521098:AACI_RS13485
uniprot id: C8WTY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

521098:AACI RS09450
gene id: 521098:AACI_RS09450
uniprot id: C8WXW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

521098:AACI RS02080
gene id: 521098:AACI_RS02080
uniprot id: C8WS20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

521098:AACI RS06480
gene id: 521098:AACI_RS06480
uniprot id: C8WW63
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

521098:AACI RS06880
gene id: 521098:AACI_RS06880
uniprot id: C8WWE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

521098:AACI RS10895
gene id: 521098:AACI_RS10895
uniprot id: C8WR44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

521098:AACI RS14585
gene id: 521098:AACI_RS14585
uniprot id: C8WVA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

521098:AACI RS06675
gene id: 521098:AACI_RS06675
uniprot id: C8WWA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

521098:AACI RS12655
gene id: 521098:AACI_RS12655
uniprot id: C8WT49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

521098:AACI RS08920
gene id: 521098:AACI_RS08920
uniprot id: C8WXK2
names: Similarity
messages: Belongs to the GSP E family.

521098:AACI RS11020
gene id: 521098:AACI_RS11020
uniprot id: C8WR65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

521098:AACI RS09265
gene id: 521098:AACI_RS09265
uniprot id: C8WXR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

521098:AACI RS13725
gene id: 521098:AACI_RS13725
uniprot id: C8WUF5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

521098:AACI RS08180
gene id: 521098:AACI_RS08180
uniprot id: C8WX52
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS13865
gene id: 521098:AACI_RS13865
uniprot id: C8WUI3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521098:AACI RS06885
gene id: 521098:AACI_RS06885
uniprot id: C8WWE4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

521098:AACI RS08365
gene id: 521098:AACI_RS08365
uniprot id: C8WX90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

521098:AACI RS03485
gene id: 521098:AACI_RS03485
uniprot id: C8WTJ5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

521098:AACI RS10425
gene id: 521098:AACI_RS10425
uniprot id: C8WQH5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS09310
gene id: 521098:AACI_RS09310
uniprot id: C8WXT6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

521098:AACI RS13310
gene id: 521098:AACI_RS13310
uniprot id: C8WTU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

521098:AACI RS02345
gene id: 521098:AACI_RS02345
uniprot id: C8WS71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

521098:AACI RS09755
gene id: 521098:AACI_RS09755
uniprot id: C8WY24
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

521098:AACI RS10485
gene id: 521098:AACI_RS10485
uniprot id: C8WQI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS08120
gene id: 521098:AACI_RS08120
uniprot id: C8WX40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

521098:AACI RS00560
gene id: 521098:AACI_RS00560
uniprot id: C8WQ67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

521098:AACI RS13940
gene id: 521098:AACI_RS13940
uniprot id: C8WUJ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS14115
gene id: 521098:AACI_RS14115
uniprot id: C8WUN5
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

521098:AACI RS09675
gene id: 521098:AACI_RS09675
uniprot id: C8WY09
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS07045
gene id: 521098:AACI_RS07045
uniprot id: C8WWH6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS13595
gene id: 521098:AACI_RS13595
uniprot id: C8WU03
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

521098:AACI RS04320
gene id: 521098:AACI_RS04320
uniprot id: C8WUE1
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

521098:AACI RS13585
gene id: 521098:AACI_RS13585
uniprot id: C8WU01
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

521098:AACI RS06945
gene id: 521098:AACI_RS06945
uniprot id: C8WWF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

521098:AACI RS04000
gene id: 521098:AACI_RS04000
uniprot id: C8WU79
names: Similarity
messages: Belongs to the PrpD family.

521098:AACI RS06575
gene id: 521098:AACI_RS06575
uniprot id: C8WW82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

521098:AACI RS07180
gene id: 521098:AACI_RS07180
uniprot id: C8WWK3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

521098:AACI RS12520
gene id: 521098:AACI_RS12520
uniprot id: C8WT25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

521098:AACI RS06375
gene id: 521098:AACI_RS06375
uniprot id: C8WW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

521098:AACI RS14815
gene id: 521098:AACI_RS14815
uniprot id: C8WYA6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

521098:AACI RS00750
gene id: 521098:AACI_RS00750
uniprot id: C8WQN2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

521098:AACI RS08615
gene id: 521098:AACI_RS08615
uniprot id: C8WXD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

521098:AACI RS11490
gene id: 521098:AACI_RS11490
uniprot id: C8WRS0
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

521098:AACI RS10680
gene id: 521098:AACI_RS10680
uniprot id: C8WR03
names: Function
names: Similarity
messages: Belongs to the peptidase S33 family.
messages: Releases the N-terminal proline from various substrates.

521098:AACI RS13380
gene id: 521098:AACI_RS13380
uniprot id: C8WTW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

521098:AACI RS09050
gene id: 521098:AACI_RS09050
uniprot id: C8WXM9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

521098:AACI RS00920
gene id: 521098:AACI_RS00920
uniprot id: C8WQR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

521098:AACI RS12940
gene id: 521098:AACI_RS12940
uniprot id: C8WTA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS09865
gene id: 521098:AACI_RS09865
uniprot id: C8WY47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

521098:AACI RS10065
gene id: 521098:AACI_RS10065
uniprot id: C8WQA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS03575
gene id: 521098:AACI_RS03575
uniprot id: C8WTL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

521098:AACI RS06095
gene id: 521098:AACI_RS06095
uniprot id: C8WVY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS11465
gene id: 521098:AACI_RS11465
uniprot id: C8WRR5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS04090
gene id: 521098:AACI_RS04090
uniprot id: C8WU96
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

521098:AACI RS02090
gene id: 521098:AACI_RS02090
uniprot id: C8WS22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

521098:AACI RS01085
gene id: 521098:AACI_RS01085
uniprot id: C8WQU6
names: Similarity
messages: Belongs to the DinB family.

521098:AACI RS13340
gene id: 521098:AACI_RS13340
uniprot id: C8WTV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

521098:AACI RS08425
gene id: 521098:AACI_RS08425
uniprot id: C8WXA2
names: Similarity
messages: Belongs to the MecA family.

521098:AACI RS11975
gene id: 521098:AACI_RS11975
uniprot id: C8WSE5
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

521098:AACI RS12000
gene id: 521098:AACI_RS12000
uniprot id: C8WSF1
names: Similarity
messages: Belongs to the transpeptidase family.

521098:AACI RS04025
gene id: 521098:AACI_RS04025
uniprot id: C8WU83
names: Similarity
messages: Belongs to the ClpA/ClpB family.

521098:AACI RS04585
gene id: 521098:AACI_RS04585
uniprot id: C8WUW8
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS11235
gene id: 521098:AACI_RS11235
uniprot id: C8WRL9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

521098:AACI RS12025
gene id: 521098:AACI_RS12025
uniprot id: C8WSF6
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

521098:AACI RS08125
gene id: 521098:AACI_RS08125
uniprot id: C8WX41
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

521098:AACI RS06550
gene id: 521098:AACI_RS06550
uniprot id: C8WW77
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

521098:AACI RS13325
gene id: 521098:AACI_RS13325
uniprot id: C8WTU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

521098:AACI RS13290
gene id: 521098:AACI_RS13290
uniprot id: C8WTU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

521098:AACI RS09065
gene id: 521098:AACI_RS09065
uniprot id: C8WXN2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

521098:AACI RS11685
gene id: 521098:AACI_RS11685
uniprot id: C8WRV8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

521098:AACI RS02005
gene id: 521098:AACI_RS02005
uniprot id: C8WS05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

521098:AACI RS12455
gene id: 521098:AACI_RS12455
uniprot id: C8WT12
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS11495
gene id: 521098:AACI_RS11495
uniprot id: C8WRS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS05925
gene id: 521098:AACI_RS05925
uniprot id: C8WVV5
names: Similarity
messages: Belongs to the GSP E family.

521098:AACI RS01555
gene id: 521098:AACI_RS01555
uniprot id: C8WRE1
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

521098:AACI RS13680
gene id: 521098:AACI_RS13680
uniprot id: C8WT54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

521098:AACI RS00290
gene id: 521098:AACI_RS00290
uniprot id: C8WQ13
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS06280
gene id: 521098:AACI_RS06280
uniprot id: C8WW24
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

521098:AACI RS14215
gene id: 521098:AACI_RS14215
uniprot id: C8WUQ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

521098:AACI RS09470
gene id: 521098:AACI_RS09470
uniprot id: C8WXW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

521098:AACI RS09490
gene id: 521098:AACI_RS09490
uniprot id: C8WXX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

521098:AACI RS08150
gene id: 521098:AACI_RS08150
uniprot id: C8WX46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

521098:AACI RS06760
gene id: 521098:AACI_RS06760
uniprot id: C8WWB7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

521098:AACI RS11560
gene id: 521098:AACI_RS11560
uniprot id: C8WRT4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

521098:AACI RS11250
gene id: 521098:AACI_RS11250
uniprot id: C8WRM2
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

521098:AACI RS13020
gene id: 521098:AACI_RS13020
uniprot id: C8WTB6
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS12135
gene id: 521098:AACI_RS12135
uniprot id: C8WSH8
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

521098:AACI RS13395
gene id: 521098:AACI_RS13395
uniprot id: C8WTW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

521098:AACI RS07780
gene id: 521098:AACI_RS07780
uniprot id: C8WWX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS06555
gene id: 521098:AACI_RS06555
uniprot id: C8WW78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

521098:AACI RS09625
gene id: 521098:AACI_RS09625
uniprot id: C8WXZ9
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

521098:AACI RS10580
gene id: 521098:AACI_RS10580
uniprot id: C8WQY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

521098:AACI RS02770
gene id: 521098:AACI_RS02770
uniprot id: C8WST9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

521098:AACI RS13415
gene id: 521098:AACI_RS13415
uniprot id: C8WTW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

521098:AACI RS10300
gene id: 521098:AACI_RS10300
uniprot id: C8WQF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS11230
gene id: 521098:AACI_RS11230
uniprot id: C8WRL8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

521098:AACI RS14095
gene id: 521098:AACI_RS14095
uniprot id: C8WUN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

521098:AACI RS04770
gene id: 521098:AACI_RS04770
uniprot id: C8WV06
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521098:AACI RS08640
gene id: 521098:AACI_RS08640
uniprot id: C8WXE4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

521098:AACI RS00890
gene id: 521098:AACI_RS00890
uniprot id: C8WQQ9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

521098:AACI RS02160
gene id: 521098:AACI_RS02160
uniprot id: C8WS33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

521098:AACI RS03280
gene id: 521098:AACI_RS03280
uniprot id: C8WTF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

521098:AACI RS12225
gene id: 521098:AACI_RS12225
uniprot id: C8WSJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

521098:AACI RS12285
gene id: 521098:AACI_RS12285
uniprot id: C8WSK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

521098:AACI RS10100
gene id: 521098:AACI_RS10100
uniprot id: C8WQB2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS01580
gene id: 521098:AACI_RS01580
uniprot id: C8WRE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

521098:AACI RS01275
gene id: 521098:AACI_RS01275
uniprot id: C8WRA7
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS09445
gene id: 521098:AACI_RS09445
uniprot id: C8WXW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

521098:AACI RS13460
gene id: 521098:AACI_RS13460
uniprot id: C8WTX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

521098:AACI RS14605
gene id: 521098:AACI_RS14605
uniprot id: C8WVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

521098:AACI RS13795
gene id: 521098:AACI_RS13795
uniprot id: C8WUG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

521098:AACI RS07490
gene id: 521098:AACI_RS07490
uniprot id: C8WQ72
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

521098:AACI RS08225
gene id: 521098:AACI_RS08225
uniprot id: C8WX61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS09345
gene id: 521098:AACI_RS09345
uniprot id: C8WXU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS14675
gene id: 521098:AACI_RS14675
uniprot id: C8WY72
names: Similarity
messages: Belongs to the GSP E family.

521098:AACI RS09075
gene id: 521098:AACI_RS09075
uniprot id: C8WXN4
names: Similarity
messages: Belongs to the peptidase S16 family.

521098:AACI RS00985
gene id: 521098:AACI_RS00985
uniprot id: C8WQS9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

521098:AACI RS11820
gene id: 521098:AACI_RS11820
uniprot id: C8WSB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS00745
gene id: 521098:AACI_RS00745
uniprot id: C8WQN1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

521098:AACI RS02385
gene id: 521098:AACI_RS02385
uniprot id: C8WS79
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

521098:AACI RS07310
gene id: 521098:AACI_RS07310
uniprot id: C8WWM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

521098:AACI RS05225
gene id: 521098:AACI_RS05225
uniprot id: C8WVG4
names: Similarity
messages: Belongs to the HepT RNase toxin family.

521098:AACI RS04215
gene id: 521098:AACI_RS04215
uniprot id: C8WUC2
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

521098:AACI RS08020
gene id: 521098:AACI_RS08020
uniprot id: C8WX19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

521098:AACI RS10075
gene id: 521098:AACI_RS10075
uniprot id: C8WQA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS00535
gene id: 521098:AACI_RS00535
uniprot id: C8WQ63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

521098:AACI RS06685
gene id: 521098:AACI_RS06685
uniprot id: C8WWA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

521098:AACI RS01885
gene id: 521098:AACI_RS01885
uniprot id: C8WQW8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS10370
gene id: 521098:AACI_RS10370
uniprot id: C8WQG5
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS13215
gene id: 521098:AACI_RS13215
uniprot id: C8WTS7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS08650
gene id: 521098:AACI_RS08650
uniprot id: C8WXE6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

521098:AACI RS08070
gene id: 521098:AACI_RS08070
uniprot id: C8WX29
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

521098:AACI RS13295
gene id: 521098:AACI_RS13295
uniprot id: C8WTU3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS01750
gene id: 521098:AACI_RS01750
uniprot id: C8WRI0
names: Similarity
messages: Belongs to the sigma-54 factor family.

521098:AACI RS00360
gene id: 521098:AACI_RS00360
uniprot id: C8WQ27
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS07900
gene id: 521098:AACI_RS07900
uniprot id: C8WWZ5
names: Similarity
messages: Belongs to the EamA transporter family.

521098:AACI RS13315
gene id: 521098:AACI_RS13315
uniprot id: C8WTU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

521098:AACI RS03935
gene id: 521098:AACI_RS03935
uniprot id: C8WU66
names: Similarity
messages: Belongs to the glycosyl hydrolase.

521098:AACI RS13750
gene id: 521098:AACI_RS13750
uniprot id: C8WUG0
names: Similarity
messages: Belongs to the peptidase C40 family.

521098:AACI RS13960
gene id: 521098:AACI_RS13960
uniprot id: C8WUK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

521098:AACI RS12950
gene id: 521098:AACI_RS12950
uniprot id: C8WTA2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

521098:AACI RS06085
gene id: 521098:AACI_RS06085
uniprot id: C8WVY7
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

521098:AACI RS13590
gene id: 521098:AACI_RS13590
uniprot id: C8WU02
names: Similarity
messages: Belongs to the ClpA/ClpB family.

521098:AACI RS08990
gene id: 521098:AACI_RS08990
uniprot id: C8WXL6
names: Similarity
messages: Belongs to the UPF0758 family.

521098:AACI RS04815
gene id: 521098:AACI_RS04815
uniprot id: C8WV15
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS06535
gene id: 521098:AACI_RS06535
uniprot id: C8WW74
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS04920
gene id: 521098:AACI_RS04920
uniprot id: C8WV35
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

521098:AACI RS14580
gene id: 521098:AACI_RS14580
uniprot id: C8WVA8
names: Similarity
messages: Belongs to the ParB family.

521098:AACI RS10195
gene id: 521098:AACI_RS10195
uniprot id: C8WQC9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS06955
gene id: 521098:AACI_RS06955
uniprot id: C8WWF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

521098:AACI RS06865
gene id: 521098:AACI_RS06865
uniprot id: C8WWE0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

521098:AACI RS11955
gene id: 521098:AACI_RS11955
uniprot id: C8WSE1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

521098:AACI RS10760
gene id: 521098:AACI_RS10760
uniprot id: C8WR19
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

521098:AACI RS06990
gene id: 521098:AACI_RS06990
uniprot id: C8WWG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

521098:AACI RS07065
gene id: 521098:AACI_RS07065
uniprot id: C8WWI0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS01895
gene id: 521098:AACI_RS01895
uniprot id: C8WRY2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

521098:AACI RS14520
gene id: 521098:AACI_RS14520
uniprot id: C8WV95
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

521098:AACI RS08315
gene id: 521098:AACI_RS08315
uniprot id: C8WX81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

521098:AACI RS12370
gene id: 521098:AACI_RS12370
uniprot id: C8WSM5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

521098:AACI RS12185
gene id: 521098:AACI_RS12185
uniprot id: C8WSI8
names: Similarity
messages: Belongs to the glutamine synthetase family.

521098:AACI RS06790
gene id: 521098:AACI_RS06790
uniprot id: C8WWC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

521098:AACI RS09660
gene id: 521098:AACI_RS09660
uniprot id: C8WY06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

521098:AACI RS08215
gene id: 521098:AACI_RS08215
uniprot id: C8WX59
names: Similarity
messages: Belongs to the TrpF family.

521098:AACI RS04885
gene id: 521098:AACI_RS04885
uniprot id: C8WV28
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

521098:AACI RS02310
gene id: 521098:AACI_RS02310
uniprot id: C8WS63
names: Similarity
messages: Belongs to the GerABKA family.

521098:AACI RS12140
gene id: 521098:AACI_RS12140
uniprot id: C8WSH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS01120
gene id: 521098:AACI_RS01120
uniprot id: C8WQV3
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS12240
gene id: 521098:AACI_RS12240
uniprot id: C8WSJ9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

521098:AACI RS09635
gene id: 521098:AACI_RS09635
uniprot id: C8WY01
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

521098:AACI RS08695
gene id: 521098:AACI_RS08695
uniprot id: C8WXF6
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

521098:AACI RS13350
gene id: 521098:AACI_RS13350
uniprot id: C8WTV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

521098:AACI RS15190
gene id: 521098:AACI_RS15190
uniprot id: C8WYI8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

521098:AACI RS07160
gene id: 521098:AACI_RS07160
uniprot id: C8WWJ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

521098:AACI RS09505
gene id: 521098:AACI_RS09505
uniprot id: C8WXX5
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

521098:AACI RS01285
gene id: 521098:AACI_RS01285
uniprot id: C8WRA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

521098:AACI RS01635
gene id: 521098:AACI_RS01635
uniprot id: C8WRF7
names: Function
messages: Required for transformation and DNA binding.

521098:AACI RS04965
gene id: 521098:AACI_RS04965
uniprot id: C8WV44
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

521098:AACI RS08600
gene id: 521098:AACI_RS08600
uniprot id: C8WXD6
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

521098:AACI RS02175
gene id: 521098:AACI_RS02175
uniprot id: C8WS36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

521098:AACI RS10260
gene id: 521098:AACI_RS10260
uniprot id: C8WQE3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS13330
gene id: 521098:AACI_RS13330
uniprot id: C8WTV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

521098:AACI RS03355
gene id: 521098:AACI_RS03355
uniprot id: C8WTG8
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS02940
gene id: 521098:AACI_RS02940
uniprot id: C8WSX2
names: Similarity
messages: Belongs to the GSP E family.

521098:AACI RS10430
gene id: 521098:AACI_RS10430
uniprot id: C8WQH6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

521098:AACI RS01240
gene id: 521098:AACI_RS01240
uniprot id: C8WQX7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

521098:AACI RS11995
gene id: 521098:AACI_RS11995
uniprot id: C8WSF0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

521098:AACI RS07055
gene id: 521098:AACI_RS07055
uniprot id: C8WWH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

521098:AACI RS11645
gene id: 521098:AACI_RS11645
uniprot id: C8WRV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

521098:AACI RS09850
gene id: 521098:AACI_RS09850
uniprot id: C8WY44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

521098:AACI RS03740
gene id: 521098:AACI_RS03740
uniprot id: C8WU26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

521098:AACI RS00175
gene id: 521098:AACI_RS00175
uniprot id: C8WPZ0
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS07235
gene id: 521098:AACI_RS07235
uniprot id: C8WWL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

521098:AACI RS04720
gene id: 521098:AACI_RS04720
uniprot id: C8WUZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

521098:AACI RS12955
gene id: 521098:AACI_RS12955
uniprot id: C8WTA3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

521098:AACI RS13570
gene id: 521098:AACI_RS13570
uniprot id: C8WTZ8
names: Similarity
messages: Belongs to the ycf81 family.

521098:AACI RS06935
gene id: 521098:AACI_RS06935
uniprot id: C8WWF5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

521098:AACI RS13360
gene id: 521098:AACI_RS13360
uniprot id: C8WTV6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

521098:AACI RS01010
gene id: 521098:AACI_RS01010
uniprot id: C8WQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

521098:AACI RS10365
gene id: 521098:AACI_RS10365
uniprot id: C8WQG4
names: Similarity
messages: Belongs to the RecJ family.

521098:AACI RS14600
gene id: 521098:AACI_RS14600
uniprot id: C8WVB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

521098:AACI RS09460
gene id: 521098:AACI_RS09460
uniprot id: C8WXW6
names: Similarity
messages: Belongs to the PstS family.

521098:AACI RS06315
gene id: 521098:AACI_RS06315
uniprot id: C8WW31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

521098:AACI RS07815
gene id: 521098:AACI_RS07815
uniprot id: C8WWX8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

521098:AACI RS07685
gene id: 521098:AACI_RS07685
uniprot id: C8WWV2
names: Similarity
messages: Belongs to the GerABKA family.

521098:AACI RS14200
gene id: 521098:AACI_RS14200
uniprot id: C8WUQ2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

521098:AACI RS06525
gene id: 521098:AACI_RS06525
uniprot id: C8WW72
names: Similarity
messages: Belongs to the YicC/YloC family.

521098:AACI RS09405
gene id: 521098:AACI_RS09405
uniprot id: C8WWR3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

521098:AACI RS07220
gene id: 521098:AACI_RS07220
uniprot id: C8WWL1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

521098:AACI RS09895
gene id: 521098:AACI_RS09895
uniprot id: C8WY54
names: Similarity
messages: Belongs to the transglycosylase Slt family.

521098:AACI RS04605
gene id: 521098:AACI_RS04605
uniprot id: C8WUX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

521098:AACI RS07960
gene id: 521098:AACI_RS07960
uniprot id: C8WX07
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

521098:AACI RS05280
gene id: 521098:AACI_RS05280
uniprot id: C8WVH3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

521098:AACI RS01165
gene id: 521098:AACI_RS01165
uniprot id: C8WQW2
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

521098:AACI RS09980
gene id: 521098:AACI_RS09980
uniprot id: C8WQ87
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

521098:AACI RS11225
gene id: 521098:AACI_RS11225
uniprot id: C8WRL7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

521098:AACI RS09905
gene id: 521098:AACI_RS09905
uniprot id: C8WY56
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

521098:AACI RS13705
gene id: 521098:AACI_RS13705
uniprot id: C8WUF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

521098:AACI RS03610
gene id: 521098:AACI_RS03610
uniprot id: C8WTM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

521098:AACI RS10615
gene id: 521098:AACI_RS10615
uniprot id: C8WQZ0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

521098:AACI RS02390
gene id: 521098:AACI_RS02390
uniprot id: C8WS80
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

521098:AACI RS04570
gene id: 521098:AACI_RS04570
uniprot id: C8WUW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS00425
gene id: 521098:AACI_RS00425
uniprot id: C8WQ40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

521098:AACI RS06460
gene id: 521098:AACI_RS06460
uniprot id: C8WW59
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

521098:AACI RS08410
gene id: 521098:AACI_RS08410
uniprot id: C8WX99
names: Similarity
messages: Belongs to the SleB family.

521098:AACI RS07545
gene id: 521098:AACI_RS07545
uniprot id: C8WWS5
names: Subcellular Location Annotation
messages: Cell membrane

521098:AACI RS10980
gene id: 521098:AACI_RS10980
uniprot id: C8WR57
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

521098:AACI RS11855
gene id: 521098:AACI_RS11855
uniprot id: C8WSB9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

521098:AACI RS14020
gene id: 521098:AACI_RS14020
uniprot id: C8WUL5
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

521098:AACI RS00675
gene id: 521098:AACI_RS00675
uniprot id: C8WQL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

521098:AACI RS09280
gene id: 521098:AACI_RS09280
uniprot id: C8WXS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

521098:AACI RS04305
gene id: 521098:AACI_RS04305
uniprot id: C8WUD8
names: Similarity
messages: Belongs to the UPF0312 family.

521098:AACI RS09035
gene id: 521098:AACI_RS09035
uniprot id: C8WXM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS13240
gene id: 521098:AACI_RS13240
uniprot id: C8WTT2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

521098:AACI RS12435
gene id: 521098:AACI_RS12435
uniprot id: C8WT08
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

521098:AACI RS10765
gene id: 521098:AACI_RS10765
uniprot id: C8WR20
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

521098:AACI RS03830
gene id: 521098:AACI_RS03830
uniprot id: C8WU44
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS07770
gene id: 521098:AACI_RS07770
uniprot id: C8WWW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

521098:AACI RS02245
gene id: 521098:AACI_RS02245
uniprot id: C8WS50
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS00455
gene id: 521098:AACI_RS00455
uniprot id: C8WQ46
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

521098:AACI RS08610
gene id: 521098:AACI_RS08610
uniprot id: C8WXD8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

521098:AACI RS04640
gene id: 521098:AACI_RS04640
uniprot id: C8WUX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

521098:AACI RS12850
gene id: 521098:AACI_RS12850
uniprot id: C8WT82
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

521098:AACI RS04155
gene id: 521098:AACI_RS04155
uniprot id: C8WUA9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS11710
gene id: 521098:AACI_RS11710
uniprot id: C8WRW4
names: Similarity
messages: Belongs to the UPF0173 family.

521098:AACI RS05995
gene id: 521098:AACI_RS05995
uniprot id: C8WVX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

521098:AACI RS03350
gene id: 521098:AACI_RS03350
uniprot id: C8WTG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Membrane

521098:AACI RS03705
gene id: 521098:AACI_RS03705
uniprot id: C8WTP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

521098:AACI RS06485
gene id: 521098:AACI_RS06485
uniprot id: C8WW64
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS05155
gene id: 521098:AACI_RS05155
uniprot id: C8WVF0
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS07670
gene id: 521098:AACI_RS07670
uniprot id: C8WWU9
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

521098:AACI RS00450
gene id: 521098:AACI_RS00450
uniprot id: C8WQ45
names: Similarity
messages: Belongs to the GPI family.

521098:AACI RS00740
gene id: 521098:AACI_RS00740
uniprot id: C8WQN0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521098:AACI RS00625
gene id: 521098:AACI_RS00625
uniprot id: C8WQK7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

521098:AACI RS09780
gene id: 521098:AACI_RS09780
uniprot id: C8WY29
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

521098:AACI RS01310
gene id: 521098:AACI_RS01310
uniprot id: C8WRB4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS09565
gene id: 521098:AACI_RS09565
uniprot id: C8WXY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

521098:AACI RS00555
gene id: 521098:AACI_RS00555
uniprot id: C8WQ66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

521098:AACI RS10175
gene id: 521098:AACI_RS10175
uniprot id: C8WQC4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

521098:AACI RS10435
gene id: 521098:AACI_RS10435
uniprot id: C8WQH7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

521098:AACI RS08620
gene id: 521098:AACI_RS08620
uniprot id: C8WXE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

521098:AACI RS04505
gene id: 521098:AACI_RS04505
uniprot id: C8WUV3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

521098:AACI RS07970
gene id: 521098:AACI_RS07970
uniprot id: C8WX09
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

521098:AACI RS06420
gene id: 521098:AACI_RS06420
uniprot id: C8WW51
names: Similarity
messages: Belongs to the YggT family.

521098:AACI RS06455
gene id: 521098:AACI_RS06455
uniprot id: C8WW58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

521098:AACI RS00520
gene id: 521098:AACI_RS00520
uniprot id: C8WQ58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

521098:AACI RS11630
gene id: 521098:AACI_RS11630
uniprot id: C8WRU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS07650
gene id: 521098:AACI_RS07650
uniprot id: C8WSQ7
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

521098:AACI RS09070
gene id: 521098:AACI_RS09070
uniprot id: C8WXN3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

521098:AACI RS13775
gene id: 521098:AACI_RS13775
uniprot id: C8WUG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

521098:AACI RS00490
gene id: 521098:AACI_RS00490
uniprot id: C8WQ51
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS09555
gene id: 521098:AACI_RS09555
uniprot id: C8WXY5
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS13915
gene id: 521098:AACI_RS13915
uniprot id: C8WUJ3
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

521098:AACI RS13160
gene id: 521098:AACI_RS13160
uniprot id: C8WTR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

521098:AACI RS09700
gene id: 521098:AACI_RS09700
uniprot id: C8WY14
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

521098:AACI RS06055
gene id: 521098:AACI_RS06055
uniprot id: C8WVY1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

521098:AACI RS04130
gene id: 521098:AACI_RS04130
uniprot id: C8WUA4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

521098:AACI RS06825
gene id: 521098:AACI_RS06825
uniprot id: C8WWD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

521098:AACI RS06495
gene id: 521098:AACI_RS06495
uniprot id: C8WW66
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS09825
gene id: 521098:AACI_RS09825
uniprot id: C8WY39
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

521098:AACI RS08560
gene id: 521098:AACI_RS08560
uniprot id: C8WXC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

521098:AACI RS06860
gene id: 521098:AACI_RS06860
uniprot id: C8WWD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

521098:AACI RS13830
gene id: 521098:AACI_RS13830
uniprot id: C8WUH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

521098:AACI RS06335
gene id: 521098:AACI_RS06335
uniprot id: C8WW35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

521098:AACI RS08250
gene id: 521098:AACI_RS08250
uniprot id: C8WX66
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

521098:AACI RS09770
gene id: 521098:AACI_RS09770
uniprot id: C8WY27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

521098:AACI RS04925
gene id: 521098:AACI_RS04925
uniprot id: C8WV36
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

521098:AACI RS08675
gene id: 521098:AACI_RS08675
uniprot id: C8WXF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

521098:AACI RS10570
gene id: 521098:AACI_RS10570
uniprot id: C8WQY1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

521098:AACI RS10335
gene id: 521098:AACI_RS10335
uniprot id: C8WQF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

521098:AACI RS06330
gene id: 521098:AACI_RS06330
uniprot id: C8WW34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS14135
gene id: 521098:AACI_RS14135
uniprot id: C8WUP0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521098:AACI RS10415
gene id: 521098:AACI_RS10415
uniprot id: C8WQH3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

521098:AACI RS14590
gene id: 521098:AACI_RS14590
uniprot id: C8WVB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

521098:AACI RS14295
gene id: 521098:AACI_RS14295
uniprot id: C8WV51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

521098:AACI RS12415
gene id: 521098:AACI_RS12415
uniprot id: C8WT04
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

521098:AACI RS09305
gene id: 521098:AACI_RS09305
uniprot id: C8WXS6
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS13305
gene id: 521098:AACI_RS13305
uniprot id: C8WTU5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

521098:AACI RS09290
gene id: 521098:AACI_RS09290
uniprot id: C8WXS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

521098:AACI RS00180
gene id: 521098:AACI_RS00180
uniprot id: C8WPZ1
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS10035
gene id: 521098:AACI_RS10035
uniprot id: C8WQ98
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

521098:AACI RS04735
gene id: 521098:AACI_RS04735
uniprot id: C8WUZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

521098:AACI RS06470
gene id: 521098:AACI_RS06470
uniprot id: C8WW61
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

521098:AACI RS10025
gene id: 521098:AACI_RS10025
uniprot id: C8WQ96
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

521098:AACI RS06670
gene id: 521098:AACI_RS06670
uniprot id: C8WWA2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

521098:AACI RS10390
gene id: 521098:AACI_RS10390
uniprot id: C8WQG9
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS12735
gene id: 521098:AACI_RS12735
uniprot id: C8WT67
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS04385
gene id: 521098:AACI_RS04385
uniprot id: C8WUS8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS08845
gene id: 521098:AACI_RS08845
uniprot id: C8WXI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

521098:AACI RS13000
gene id: 521098:AACI_RS13000
uniprot id: C8WTB2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS01945
gene id: 521098:AACI_RS01945
uniprot id: C8WRZ3
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

521098:AACI RS09650
gene id: 521098:AACI_RS09650
uniprot id: C8WY04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

521098:AACI RS09475
gene id: 521098:AACI_RS09475
uniprot id: C8WXW9
names: Similarity
messages: Belongs to the isochorismate synthase family.

521098:AACI RS02165
gene id: 521098:AACI_RS02165
uniprot id: C8WS34
names: Similarity
messages: Belongs to the MotB family.

521098:AACI RS13430
gene id: 521098:AACI_RS13430
uniprot id: C8WTX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

521098:AACI RS11150
gene id: 521098:AACI_RS11150
uniprot id: C8WR94
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS03475
gene id: 521098:AACI_RS03475
uniprot id: C8WTJ3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

521098:AACI RS04520
gene id: 521098:AACI_RS04520
uniprot id: C8WUV6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

521098:AACI RS01725
gene id: 521098:AACI_RS01725
uniprot id: C8WRH5
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

521098:AACI RS11065
gene id: 521098:AACI_RS11065
uniprot id: C8WR75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS14610
gene id: 521098:AACI_RS14610
uniprot id: C8WVB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

521098:AACI RS00525
gene id: 521098:AACI_RS00525
uniprot id: C8WQ61
names: Similarity
messages: Belongs to the asparagine synthetase family.

521098:AACI RS10830
gene id: 521098:AACI_RS10830
uniprot id: C8WR32
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS04970
gene id: 521098:AACI_RS04970
uniprot id: C8WV45
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

521098:AACI RS04475
gene id: 521098:AACI_RS04475
uniprot id: C8WUU7
names: Similarity
messages: Belongs to the EamA transporter family.

521098:AACI RS12620
gene id: 521098:AACI_RS12620
uniprot id: C8WT44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

521098:AACI RS04160
gene id: 521098:AACI_RS04160
uniprot id: C8WUB0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

521098:AACI RS06380
gene id: 521098:AACI_RS06380
uniprot id: C8WW43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

521098:AACI RS11000
gene id: 521098:AACI_RS11000
uniprot id: C8WR61
names: Similarity
messages: Belongs to the citrate synthase family.

521098:AACI RS05235
gene id: 521098:AACI_RS05235
uniprot id: C8WVG6
names: Similarity
messages: Belongs to the peptidase C40 family.

521098:AACI RS09960
gene id: 521098:AACI_RS09960
uniprot id: C8WQ83
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS01455
gene id: 521098:AACI_RS01455
uniprot id: C8WRC5
names: Similarity
messages: Belongs to the IMPACT family.

521098:AACI RS13270
gene id: 521098:AACI_RS13270
uniprot id: C8WTT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

521098:AACI RS03230
gene id: 521098:AACI_RS03230
uniprot id: C8WTE3
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

521098:AACI RS02065
gene id: 521098:AACI_RS02065
uniprot id: C8WS17
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

521098:AACI RS14545
gene id: 521098:AACI_RS14545
uniprot id: C8WVA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

521098:AACI RS04110
gene id: 521098:AACI_RS04110
uniprot id: C8WUA0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

521098:AACI RS10375
gene id: 521098:AACI_RS10375
uniprot id: C8WQG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

521098:AACI RS01145
gene id: 521098:AACI_RS01145
uniprot id: C8WQV8
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

521098:AACI RS13525
gene id: 521098:AACI_RS13525
uniprot id: C8WTY9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

521098:AACI RS07705
gene id: 521098:AACI_RS07705
uniprot id: C8WWV6
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

521098:AACI RS12045
gene id: 521098:AACI_RS12045
uniprot id: C8WSG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

521098:AACI RS14850
gene id: 521098:AACI_RS14850
uniprot id: C8WYB3
names: Similarity
messages: Belongs to the UPF0758 family.

521098:AACI RS00910
gene id: 521098:AACI_RS00910
uniprot id: C8WQR3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS13505
gene id: 521098:AACI_RS13505
uniprot id: C8WTY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

521098:AACI RS00225
gene id: 521098:AACI_RS00225
uniprot id: C8WQ00
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS12480
gene id: 521098:AACI_RS12480
uniprot id: C8WT17
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS09995
gene id: 521098:AACI_RS09995
uniprot id: C8WQ90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

521098:AACI RS07175
gene id: 521098:AACI_RS07175
uniprot id: C8WWK2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS05115
gene id: 521098:AACI_RS05115
uniprot id: C8WVE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

521098:AACI RS02700
gene id: 521098:AACI_RS02700
uniprot id: C8WSS4
names: Similarity
messages: Belongs to the universal stress protein A family.

521098:AACI RS02645
gene id: 521098:AACI_RS02645
uniprot id: C8WSR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

521098:AACI RS00190
gene id: 521098:AACI_RS00190
uniprot id: C8WPZ3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

521098:AACI RS06660
gene id: 521098:AACI_RS06660
uniprot id: C8WWA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

521098:AACI RS10350
gene id: 521098:AACI_RS10350
uniprot id: C8WQG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS13610
gene id: 521098:AACI_RS13610
uniprot id: C8WU06
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

521098:AACI RS10515
gene id: 521098:AACI_RS10515
uniprot id: C8WQJ3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

521098:AACI RS11925
gene id: 521098:AACI_RS11925
uniprot id: C8WSD5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

521098:AACI RS13320
gene id: 521098:AACI_RS13320
uniprot id: C8WTU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

521098:AACI RS07880
gene id: 521098:AACI_RS07880
uniprot id: C8WWZ1
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS03775
gene id: 521098:AACI_RS03775
uniprot id: C8WU33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

521098:AACI RS08370
gene id: 521098:AACI_RS08370
uniprot id: C8WX91
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

521098:AACI RS08310
gene id: 521098:AACI_RS08310
uniprot id: C8WX80
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS08745
gene id: 521098:AACI_RS08745
uniprot id: C8WXG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

521098:AACI RS06780
gene id: 521098:AACI_RS06780
uniprot id: C8WWC2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

521098:AACI RS13115
gene id: 521098:AACI_RS13115
uniprot id: C8WTQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

521098:AACI RS03460
gene id: 521098:AACI_RS03460
uniprot id: C8WTI8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS11990
gene id: 521098:AACI_RS11990
uniprot id: C8WSE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

521098:AACI RS06385
gene id: 521098:AACI_RS06385
uniprot id: C8WW44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

521098:AACI RS11750
gene id: 521098:AACI_RS11750
uniprot id: C8WRX2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

521098:AACI RS14530
gene id: 521098:AACI_RS14530
uniprot id: C8WV97
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

521098:AACI RS14365
gene id: 521098:AACI_RS14365
uniprot id: C8WV64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

521098:AACI RS13950
gene id: 521098:AACI_RS13950
uniprot id: C8WUK1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

521098:AACI RS07580
gene id: 521098:AACI_RS07580
uniprot id: C8WWR3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

521098:AACI RS00735
gene id: 521098:AACI_RS00735
uniprot id: C8WQM9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521098:AACI RS00415
gene id: 521098:AACI_RS00415
uniprot id: C8WQ38
names: Similarity
messages: Belongs to the peptidase M29 family.

521098:AACI RS05495
gene id: 521098:AACI_RS05495
uniprot id: C8WVL7
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS15455
gene id: 521098:AACI_RS15455
uniprot id: C8WYP5
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS13695
gene id: 521098:AACI_RS13695
uniprot id: C8WUE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

521098:AACI RS03820
gene id: 521098:AACI_RS03820
uniprot id: C8WU42
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

521098:AACI RS12700
gene id: 521098:AACI_RS12700
uniprot id: C8WT59
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS08770
gene id: 521098:AACI_RS08770
uniprot id: C8WXH1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

521098:AACI RS00670
gene id: 521098:AACI_RS00670
uniprot id: C8WQL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

521098:AACI RS11665
gene id: 521098:AACI_RS11665
uniprot id: C8WRV4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS00780
gene id: 521098:AACI_RS00780
uniprot id: C8WQN8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

521098:AACI RS09455
gene id: 521098:AACI_RS09455
uniprot id: C8WXW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

521098:AACI RS14150
gene id: 521098:AACI_RS14150
uniprot id: C8WUP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS10410
gene id: 521098:AACI_RS10410
uniprot id: C8WQH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

521098:AACI RS05655
gene id: 521098:AACI_RS05655
uniprot id: C8WVP7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

521098:AACI RS11840
gene id: 521098:AACI_RS11840
uniprot id: C8WSB6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

521098:AACI RS01695
gene id: 521098:AACI_RS01695
uniprot id: C8WRG9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

521098:AACI RS12755
gene id: 521098:AACI_RS12755
uniprot id: C8WT71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

521098:AACI RS06450
gene id: 521098:AACI_RS06450
uniprot id: C8WW57
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

521098:AACI RS13735
gene id: 521098:AACI_RS13735
uniprot id: C8WUF7
names: Similarity
messages: Belongs to the UPF0340 family.

521098:AACI RS10240
gene id: 521098:AACI_RS10240
uniprot id: C8WQD9
names: Similarity
messages: Belongs to the peptidase C40 family.

521098:AACI RS01790
gene id: 521098:AACI_RS01790
uniprot id: C8WRI9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS05285
gene id: 521098:AACI_RS05285
uniprot id: C8WVH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Spore core

521098:AACI RS03060
gene id: 521098:AACI_RS03060
uniprot id: C8WSZ4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

521098:AACI RS11195
gene id: 521098:AACI_RS11195
uniprot id: C8WRL1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

521098:AACI RS04005
gene id: 521098:AACI_RS04005
uniprot id: C8WU80
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

521098:AACI RS10995
gene id: 521098:AACI_RS10995
uniprot id: C8WR60
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

521098:AACI RS05100
gene id: 521098:AACI_RS05100
uniprot id: C8WVD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

521098:AACI RS10530
gene id: 521098:AACI_RS10530
uniprot id: C8WQJ7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

521098:AACI RS07125
gene id: 521098:AACI_RS07125
uniprot id: C8WWJ2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

521098:AACI RS10950
gene id: 521098:AACI_RS10950
uniprot id: C8WR51
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

521098:AACI RS09360
gene id: 521098:AACI_RS09360
uniprot id: C8WXU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

521098:AACI RS01185
gene id: 521098:AACI_RS01185
uniprot id: C8WQW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

521098:AACI RS01530
gene id: 521098:AACI_RS01530
uniprot id: C8WRD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

521098:AACI RS13970
gene id: 521098:AACI_RS13970
uniprot id: C8WUK5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

521098:AACI RS08795
gene id: 521098:AACI_RS08795
uniprot id: C8WXH6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

521098:AACI RS12090
gene id: 521098:AACI_RS12090
uniprot id: C8WSG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

521098:AACI RS08790
gene id: 521098:AACI_RS08790
uniprot id: C8WXH5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

521098:AACI RS11270
gene id: 521098:AACI_RS11270
uniprot id: C8WRM6
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS10715
gene id: 521098:AACI_RS10715
uniprot id: C8WR10
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

521098:AACI RS13230
gene id: 521098:AACI_RS13230
uniprot id: C8WTT0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

521098:AACI RS00400
gene id: 521098:AACI_RS00400
uniprot id: C8WQ35
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

521098:AACI RS13985
gene id: 521098:AACI_RS13985
uniprot id: C8WUK8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

521098:AACI RS09530
gene id: 521098:AACI_RS09530
uniprot id: C8WXY0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

521098:AACI RS11050
gene id: 521098:AACI_RS11050
uniprot id: C8WR72
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

521098:AACI RS11730
gene id: 521098:AACI_RS11730
uniprot id: C8WRW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

521098:AACI RS02410
gene id: 521098:AACI_RS02410
uniprot id: C8WS83
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

521098:AACI RS01820
gene id: 521098:AACI_RS01820
uniprot id: C8WRJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

521098:AACI RS10325
gene id: 521098:AACI_RS10325
uniprot id: C8WQF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

521098:AACI RS03990
gene id: 521098:AACI_RS03990
uniprot id: C8WU77
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

521098:AACI RS09870
gene id: 521098:AACI_RS09870
uniprot id: C8WY48
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

521098:AACI RS08320
gene id: 521098:AACI_RS08320
uniprot id: C8WX82
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

521098:AACI RS09015
gene id: 521098:AACI_RS09015
uniprot id: C8WXM1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

521098:AACI RS05570
gene id: 521098:AACI_RS05570
uniprot id: C8WVN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

521098:AACI RS11310
gene id: 521098:AACI_RS11310
uniprot id: C8WRN4
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS02240
gene id: 521098:AACI_RS02240
uniprot id: C8WS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

521098:AACI RS01805
gene id: 521098:AACI_RS01805
uniprot id: C8WRJ2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

521098:AACI RS01630
gene id: 521098:AACI_RS01630
uniprot id: C8WRF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

521098:AACI RS09570
gene id: 521098:AACI_RS09570
uniprot id: C8WXY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

521098:AACI RS06415
gene id: 521098:AACI_RS06415
uniprot id: C8WW50
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

521098:AACI RS07300
gene id: 521098:AACI_RS07300
uniprot id: C8WWM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

521098:AACI RS13785
gene id: 521098:AACI_RS13785
uniprot id: C8WUG7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

521098:AACI RS05130
gene id: 521098:AACI_RS05130
uniprot id: C8WVE5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

521098:AACI RS13670
gene id: 521098:AACI_RS13670
uniprot id: C8WU18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

521098:AACI RS07920
gene id: 521098:AACI_RS07920
uniprot id: C8WWZ9
names: Similarity
messages: Belongs to the FBPase class 2 family.

521098:AACI RS10180
gene id: 521098:AACI_RS10180
uniprot id: C8WQC5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

521098:AACI RS10860
gene id: 521098:AACI_RS10860
uniprot id: C8WR37
names: Subcellular Location Annotation
messages: Cytoplasm

521098:AACI RS03030
gene id: 521098:AACI_RS03030
uniprot id: C8WSY9
names: Similarity
messages: Belongs to the GSP E family.

521098:AACI RS09860
gene id: 521098:AACI_RS09860
uniprot id: C8WY46
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

521098:AACI RS08360
gene id: 521098:AACI_RS08360
uniprot id: C8WX89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

521098:AACI RS04165
gene id: 521098:AACI_RS04165
uniprot id: C8WUB2
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS13145
gene id: 521098:AACI_RS13145
uniprot id: C8WTR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

521098:AACI RS08980
gene id: 521098:AACI_RS08980
uniprot id: C8WXL4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

521098:AACI RS02210
gene id: 521098:AACI_RS02210
uniprot id: C8WS43
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

521098:AACI RS05665
gene id: 521098:AACI_RS05665
uniprot id: C8WVP9
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

521098:AACI RS03565
gene id: 521098:AACI_RS03565
uniprot id: C8WTL2
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS08655
gene id: 521098:AACI_RS08655
uniprot id: C8WXE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

521098:AACI RS00685
gene id: 521098:AACI_RS00685
uniprot id: C8WQL9
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
messages: Homodimer.

521098:AACI RS00300
gene id: 521098:AACI_RS00300
uniprot id: C8WQ15
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS08065
gene id: 521098:AACI_RS08065
uniprot id: C8WX28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS12605
gene id: 521098:AACI_RS12605
uniprot id: C8WT41
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS12925
gene id: 521098:AACI_RS12925
uniprot id: C8WT97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

521098:AACI RS13860
gene id: 521098:AACI_RS13860
uniprot id: C8WUI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

521098:AACI RS14080
gene id: 521098:AACI_RS14080
uniprot id: C8WUM8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS01060
gene id: 521098:AACI_RS01060
uniprot id: C8WQU4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS12915
gene id: 521098:AACI_RS12915
uniprot id: C8WT95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

521098:AACI RS13155
gene id: 521098:AACI_RS13155
uniprot id: C8WTR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

521098:AACI RS00160
gene id: 521098:AACI_RS00160
uniprot id: C8WPY7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

521098:AACI RS13300
gene id: 521098:AACI_RS13300
uniprot id: C8WTU4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

521098:AACI RS11255
gene id: 521098:AACI_RS11255
uniprot id: C8WRM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

521098:AACI RS08210
gene id: 521098:AACI_RS08210
uniprot id: C8WX58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

521098:AACI RS00025
gene id: 521098:AACI_RS00025
uniprot id: C8WXT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

521098:AACI RS14340
gene id: 521098:AACI_RS14340
uniprot id: C8WV59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

521098:AACI RS04790
gene id: 521098:AACI_RS04790
uniprot id: C8WV10
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

521098:AACI RS00610
gene id: 521098:AACI_RS00610
uniprot id: C8WQK3
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS13855
gene id: 521098:AACI_RS13855
uniprot id: C8WUI1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

521098:AACI RS03815
gene id: 521098:AACI_RS03815
uniprot id: C8WU41
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

521098:AACI RS14500
gene id: 521098:AACI_RS14500
uniprot id: C8WV90
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

521098:AACI RS12495
gene id: 521098:AACI_RS12495
uniprot id: C8WT20
names: Similarity
messages: Belongs to the malate synthase family.

521098:AACI RS08350
gene id: 521098:AACI_RS08350
uniprot id: C8WX87
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

521098:AACI RS13815
gene id: 521098:AACI_RS13815
uniprot id: C8WUH3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS08590
gene id: 521098:AACI_RS08590
uniprot id: C8WXD4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

521098:AACI RS03040
gene id: 521098:AACI_RS03040
uniprot id: C8WSZ1
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS11535
gene id: 521098:AACI_RS11535
uniprot id: C8WRS9
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS04455
gene id: 521098:AACI_RS04455
uniprot id: C8WUU3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

521098:AACI RS01590
gene id: 521098:AACI_RS01590
uniprot id: C8WRE8
names: Similarity
messages: Belongs to the transpeptidase family.

521098:AACI RS13685
gene id: 521098:AACI_RS13685
uniprot id: C8WUE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

521098:AACI RS08510
gene id: 521098:AACI_RS08510
uniprot id: C8WXB7
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS07100
gene id: 521098:AACI_RS07100
uniprot id: C8WWI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

521098:AACI RS13185
gene id: 521098:AACI_RS13185
uniprot id: C8WTS1
names: Similarity
messages: Belongs to the asp23 family.

521098:AACI RS10460
gene id: 521098:AACI_RS10460
uniprot id: C8WQI2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS00325
gene id: 521098:AACI_RS00325
uniprot id: C8WQ20
names: Similarity
messages: Belongs to the glycosyl hydrolase 67 family.

521098:AACI RS14350
gene id: 521098:AACI_RS14350
uniprot id: C8WV61
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

521098:AACI RS04645
gene id: 521098:AACI_RS04645
uniprot id: C8WUY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

521098:AACI RS06855
gene id: 521098:AACI_RS06855
uniprot id: C8WWD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

521098:AACI RS01100
gene id: 521098:AACI_RS01100
uniprot id: C8WQU9
names: Similarity
messages: Belongs to the EamA transporter family.

521098:AACI RS04660
gene id: 521098:AACI_RS04660
uniprot id: C8WUY3
names: Similarity
messages: Belongs to the EamA transporter family.

521098:AACI RS01055
gene id: 521098:AACI_RS01055
uniprot id: C8WQU3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

521098:AACI RS04620
gene id: 521098:AACI_RS04620
uniprot id: C8WUX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

521098:AACI RS06080
gene id: 521098:AACI_RS06080
uniprot id: C8WVY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

521098:AACI RS13440
gene id: 521098:AACI_RS13440
uniprot id: C8WTX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

521098:AACI RS06995
gene id: 521098:AACI_RS06995
uniprot id: C8WWG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

521098:AACI RS01290
gene id: 521098:AACI_RS01290
uniprot id: C8WRB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

521098:AACI RS10225
gene id: 521098:AACI_RS10225
uniprot id: C8WQD6
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

521098:AACI RS12830
gene id: 521098:AACI_RS12830
uniprot id: C8WT78
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

521098:AACI RS01830
gene id: 521098:AACI_RS01830
uniprot id: C8WRJ7
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS04675
gene id: 521098:AACI_RS04675
uniprot id: C8WUY7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

521098:AACI RS06560
gene id: 521098:AACI_RS06560
uniprot id: C8WW79
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

521098:AACI RS06875
gene id: 521098:AACI_RS06875
uniprot id: C8WWE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

521098:AACI RS14505
gene id: 521098:AACI_RS14505
uniprot id: C8WV91
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

521098:AACI RS03245
gene id: 521098:AACI_RS03245
uniprot id: C8WTE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521098:AACI RS10140
gene id: 521098:AACI_RS10140
uniprot id: C8WQC0
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

521098:AACI RS01910
gene id: 521098:AACI_RS01910
uniprot id: C8WRY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

521098:AACI RS06590
gene id: 521098:AACI_RS06590
uniprot id: C8WW84
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

521098:AACI RS04145
gene id: 521098:AACI_RS04145
uniprot id: C8WUA7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

521098:AACI RS01090
gene id: 521098:AACI_RS01090
uniprot id: C8WQU7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

521098:AACI RS06210
gene id: 521098:AACI_RS06210
uniprot id: C8WW10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

521098:AACI RS07725
gene id: 521098:AACI_RS07725
uniprot id: C8WWW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

521098:AACI RS11045
gene id: 521098:AACI_RS11045
uniprot id: C8WR70
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS06540
gene id: 521098:AACI_RS06540
uniprot id: C8WW75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

521098:AACI RS14460
gene id: 521098:AACI_RS14460
uniprot id: C8WV82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

521098:AACI RS12490
gene id: 521098:AACI_RS12490
uniprot id: C8WT19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

521098:AACI RS03630
gene id: 521098:AACI_RS03630
uniprot id: C8WTM5
names: Similarity
messages: Belongs to the acyltransferase 3 family.

521098:AACI RS04210
gene id: 521098:AACI_RS04210
uniprot id: C8WUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

521098:AACI RS09370
gene id: 521098:AACI_RS09370
uniprot id: C8WXU7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

521098:AACI RS04140
gene id: 521098:AACI_RS04140
uniprot id: C8WUA6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

521098:AACI RS01685
gene id: 521098:AACI_RS01685
uniprot id: C8WRG7
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS08205
gene id: 521098:AACI_RS08205
uniprot id: C8WX57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

521098:AACI RS12215
gene id: 521098:AACI_RS12215
uniprot id: C8WSJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS01475
gene id: 521098:AACI_RS01475
uniprot id: C8WRC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

521098:AACI RS13235
gene id: 521098:AACI_RS13235
uniprot id: C8WTT1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS01095
gene id: 521098:AACI_RS01095
uniprot id: C8WQU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS04845
gene id: 521098:AACI_RS04845
uniprot id: C8WV21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS04525
gene id: 521098:AACI_RS04525
uniprot id: C8WUV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

521098:AACI RS03540
gene id: 521098:AACI_RS03540
uniprot id: C8WTK6
names: Similarity
messages: Belongs to the Dps family.

521098:AACI RS11510
gene id: 521098:AACI_RS11510
uniprot id: C8WRS4
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

521098:AACI RS05860
gene id: 521098:AACI_RS05860
uniprot id: C8WVU1
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS05305
gene id: 521098:AACI_RS05305
uniprot id: C8WVH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

521098:AACI RS01160
gene id: 521098:AACI_RS01160
uniprot id: C8WQW1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

521098:AACI RS10360
gene id: 521098:AACI_RS10360
uniprot id: C8WQG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

521098:AACI RS01560
gene id: 521098:AACI_RS01560
uniprot id: C8WRE2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

521098:AACI RS09790
gene id: 521098:AACI_RS09790
uniprot id: C8WY32
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

521098:AACI RS06765
gene id: 521098:AACI_RS06765
uniprot id: C8WWB8
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS09300
gene id: 521098:AACI_RS09300
uniprot id: C8WXS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

521098:AACI RS00410
gene id: 521098:AACI_RS00410
uniprot id: C8WQ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS05585
gene id: 521098:AACI_RS05585
uniprot id: C8WVN4
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS09925
gene id: 521098:AACI_RS09925
uniprot id: C8WQ76
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS14170
gene id: 521098:AACI_RS14170
uniprot id: C8WUP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

521098:AACI RS11175
gene id: 521098:AACI_RS11175
uniprot id: C8WR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS13625
gene id: 521098:AACI_RS13625
uniprot id: C8WU09
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

521098:AACI RS14920
gene id: 521098:AACI_RS14920
uniprot id: C8WYD0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

521098:AACI RS00015
gene id: 521098:AACI_RS00015
uniprot id: C8WXS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

521098:AACI RS09110
gene id: 521098:AACI_RS09110
uniprot id: C8WXN9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

521098:AACI RS02100
gene id: 521098:AACI_RS02100
uniprot id: C8WS24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

521098:AACI RS06395
gene id: 521098:AACI_RS06395
uniprot id: C8WW46
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

521098:AACI RS11615
gene id: 521098:AACI_RS11615
uniprot id: C8WRU4
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

521098:AACI RS00950
gene id: 521098:AACI_RS00950
uniprot id: C8WQS1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

521098:AACI RS04295
gene id: 521098:AACI_RS04295
uniprot id: C8WUD6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

521098:AACI RS06300
gene id: 521098:AACI_RS06300
uniprot id: C8WW28
names: Similarity
messages: Belongs to the transpeptidase family.

521098:AACI RS07555
gene id: 521098:AACI_RS07555
uniprot id: C8WQ72
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

521098:AACI RS10720
gene id: 521098:AACI_RS10720
uniprot id: C8WR11
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

521098:AACI RS06430
gene id: 521098:AACI_RS06430
uniprot id: C8WW53
names: Subcellular Location Annotation
messages: Cytoplasm

521098:AACI RS06715
gene id: 521098:AACI_RS06715
uniprot id: C8WWB1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

521098:AACI RS13515
gene id: 521098:AACI_RS13515
uniprot id: C8WTY7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

521098:AACI RS02235
gene id: 521098:AACI_RS02235
uniprot id: C8WS48
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

521098:AACI RS00295
gene id: 521098:AACI_RS00295
uniprot id: C8WQ14
names: Similarity
messages: Belongs to the UPF0111 family.

521098:AACI RS10170
gene id: 521098:AACI_RS10170
uniprot id: C8WQC3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

521098:AACI RS13220
gene id: 521098:AACI_RS13220
uniprot id: C8WTS8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

521098:AACI RS09830
gene id: 521098:AACI_RS09830
uniprot id: C8WY40
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS10790
gene id: 521098:AACI_RS10790
uniprot id: C8WR24
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

521098:AACI RS11760
gene id: 521098:AACI_RS11760
uniprot id: C8WRX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

521098:AACI RS12395
gene id: 521098:AACI_RS12395
uniprot id: C8WSN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

521098:AACI RS11530
gene id: 521098:AACI_RS11530
uniprot id: C8WRS8
names: Similarity
messages: Belongs to the transpeptidase family.

521098:AACI RS00405
gene id: 521098:AACI_RS00405
uniprot id: C8WQ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS12280
gene id: 521098:AACI_RS12280
uniprot id: C8WSK7
names: Subcellular Location Annotation
messages: Cell membrane

521098:AACI RS13425
gene id: 521098:AACI_RS13425
uniprot id: C8WTW9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

521098:AACI RS10010
gene id: 521098:AACI_RS10010
uniprot id: C8WQ93
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

521098:AACI RS12365
gene id: 521098:AACI_RS12365
uniprot id: C8WSM4
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS13620
gene id: 521098:AACI_RS13620
uniprot id: C8WU08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

521098:AACI RS08865
gene id: 521098:AACI_RS08865
uniprot id: C8WXJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

521098:AACI RS06870
gene id: 521098:AACI_RS06870
uniprot id: C8WWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

521098:AACI RS09160
gene id: 521098:AACI_RS09160
uniprot id: C8WXP9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS13450
gene id: 521098:AACI_RS13450
uniprot id: C8WTX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

521098:AACI RS10545
gene id: 521098:AACI_RS10545
uniprot id: C8WQK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

521098:AACI RS09010
gene id: 521098:AACI_RS09010
uniprot id: C8WXM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

521098:AACI RS08105
gene id: 521098:AACI_RS08105
uniprot id: C8WX37
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

521098:AACI RS11290
gene id: 521098:AACI_RS11290
uniprot id: C8WRN0
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS04930
gene id: 521098:AACI_RS04930
uniprot id: C8WV37
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

521098:AACI RS07625
gene id: 521098:AACI_RS07625
uniprot id: C8WWU2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

521098:AACI RS02605
gene id: 521098:AACI_RS02605
uniprot id: C8WSQ7
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

521098:AACI RS14060
gene id: 521098:AACI_RS14060
uniprot id: C8WUM4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

521098:AACI RS06400
gene id: 521098:AACI_RS06400
uniprot id: C8WW47
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

521098:AACI RS09955
gene id: 521098:AACI_RS09955
uniprot id: C8WQ82
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

521098:AACI RS01115
gene id: 521098:AACI_RS01115
uniprot id: C8WQV2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

521098:AACI RS13250
gene id: 521098:AACI_RS13250
uniprot id: C8WTT4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

521098:AACI RS13805
gene id: 521098:AACI_RS13805
uniprot id: C8WUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

521098:AACI RS04335
gene id: 521098:AACI_RS04335
uniprot id: C8WUE4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

521098:AACI RS14620
gene id: 521098:AACI_RS14620
uniprot id: C8WVB6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

521098:AACI RS01990
gene id: 521098:AACI_RS01990
uniprot id: C8WS02
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

521098:AACI RS09785
gene id: 521098:AACI_RS09785
uniprot id: C8WY31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

521098:AACI RS01675
gene id: 521098:AACI_RS01675
uniprot id: C8WRG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

521098:AACI RS10110
gene id: 521098:AACI_RS10110
uniprot id: C8WQB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS10320
gene id: 521098:AACI_RS10320
uniprot id: C8WQF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

521098:AACI RS02505
gene id: 521098:AACI_RS02505
uniprot id: C8WSN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

521098:AACI RS10420
gene id: 521098:AACI_RS10420
uniprot id: C8WQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

521098:AACI RS09610
gene id: 521098:AACI_RS09610
uniprot id: C8WXZ6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

521098:AACI RS04540
gene id: 521098:AACI_RS04540
uniprot id: C8WUW0
names: Similarity
messages: Belongs to the EamA transporter family.

521098:AACI RS09430
gene id: 521098:AACI_RS09430
uniprot id: C8WXW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

521098:AACI RS13420
gene id: 521098:AACI_RS13420
uniprot id: C8WTW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

521098:AACI RS13345
gene id: 521098:AACI_RS13345
uniprot id: C8WTV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

521098:AACI RS03730
gene id: 521098:AACI_RS03730
uniprot id: C8WU24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

521098:AACI RS14425
gene id: 521098:AACI_RS14425
uniprot id: C8WV76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

521098:AACI RS06020
gene id: 521098:AACI_RS06020
uniprot id: C8WVX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

521098:AACI RS06515
gene id: 521098:AACI_RS06515
uniprot id: C8WW70
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

521098:AACI RS15925
gene id: 521098:AACI_RS15925
uniprot id: C8WW96
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

521098:AACI RS02195
gene id: 521098:AACI_RS02195
uniprot id: C8WS40
names: Similarity
messages: Belongs to the Nudix hydrolase family.

521098:AACI RS04895
gene id: 521098:AACI_RS04895
uniprot id: C8WV30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Monomer.

521098:AACI RS04690
gene id: 521098:AACI_RS04690
uniprot id: C8WUZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

521098:AACI RS10215
gene id: 521098:AACI_RS10215
uniprot id: C8WQD4
names: Subcellular Location Annotation
messages: Cell membrane

521098:AACI RS00275
gene id: 521098:AACI_RS00275
uniprot id: C8WQ10
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

521098:AACI RS14380
gene id: 521098:AACI_RS14380
uniprot id: C8WV67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

521098:AACI RS04290
gene id: 521098:AACI_RS04290
uniprot id: C8WUD5
names: Similarity
messages: Belongs to the thioredoxin family.

521098:AACI RS04085
gene id: 521098:AACI_RS04085
uniprot id: C8WU95
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

521098:AACI RS06665
gene id: 521098:AACI_RS06665
uniprot id: C8WWA1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

521098:AACI RS13455
gene id: 521098:AACI_RS13455
uniprot id: C8WTX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

521098:AACI RS04590
gene id: 521098:AACI_RS04590
uniprot id: C8WUW9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

521098:AACI RS06370
gene id: 521098:AACI_RS06370
uniprot id: C8WW41
names: Similarity
messages: Belongs to the UPF0749 family.

521098:AACI RS08100
gene id: 521098:AACI_RS08100
uniprot id: C8WX36
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

521098:AACI RS03735
gene id: 521098:AACI_RS03735
uniprot id: C8WU25
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

521098:AACI RS04600
gene id: 521098:AACI_RS04600
uniprot id: C8WUX1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

521098:AACI RS05050
gene id: 521098:AACI_RS05050
uniprot id: C8WVC9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

521098:AACI RS13150
gene id: 521098:AACI_RS13150
uniprot id: C8WTR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

521098:AACI RS13100
gene id: 521098:AACI_RS13100
uniprot id: C8WTQ4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

521098:AACI RS06695
gene id: 521098:AACI_RS06695
uniprot id: C8WWA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

521098:AACI RS08005
gene id: 521098:AACI_RS08005
uniprot id: C8WX16
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

521098:AACI RS11640
gene id: 521098:AACI_RS11640
uniprot id: C8WRU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

521098:AACI RS10290
gene id: 521098:AACI_RS10290
uniprot id: C8WQE9
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS13910
gene id: 521098:AACI_RS13910
uniprot id: C8WUJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

521098:AACI RS02145
gene id: 521098:AACI_RS02145
uniprot id: C8WS30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

521098:AACI RS01205
gene id: 521098:AACI_RS01205
uniprot id: C8WQX1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS08840
gene id: 521098:AACI_RS08840
uniprot id: C8WXI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

521098:AACI RS05765
gene id: 521098:AACI_RS05765
uniprot id: C8WVS2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

521098:AACI RS07185
gene id: 521098:AACI_RS07185
uniprot id: C8WWK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

521098:AACI RS13025
gene id: 521098:AACI_RS13025
uniprot id: C8WTB7
names: Similarity
messages: Belongs to the UPF0111 family.

521098:AACI RS04150
gene id: 521098:AACI_RS04150
uniprot id: C8WUA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

521098:AACI RS07825
gene id: 521098:AACI_RS07825
uniprot id: C8WWY0
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

521098:AACI RS05980
gene id: 521098:AACI_RS05980
uniprot id: C8WVW7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521098:AACI RS14165
gene id: 521098:AACI_RS14165
uniprot id: C8WUP6
names: Similarity
messages: Belongs to the 3-hydroxybenzoate 6-hydroxylase family.

521098:AACI RS07385
gene id: 521098:AACI_RS07385
uniprot id: C8WWP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

521098:AACI RS11325
gene id: 521098:AACI_RS11325
uniprot id: C8WRN7
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

521098:AACI RS01965
gene id: 521098:AACI_RS01965
uniprot id: C8WRZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

521098:AACI RS14310
gene id: 521098:AACI_RS14310
uniprot id: C8WV54
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

521098:AACI RS12065
gene id: 521098:AACI_RS12065
uniprot id: P33247
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the terpene cyclase/mutase family.
messages: Catalyzes the cyclization of squalene into hopene.
messages: Cell membrane

521098:AACI RS06200
gene id: 521098:AACI_RS06200
uniprot id: C8WW08
names: Similarity
messages: Belongs to the WrbA family.

521098:AACI RS00905
gene id: 521098:AACI_RS00905
uniprot id: C8WQR2
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

521098:AACI RS06215
gene id: 521098:AACI_RS06215
uniprot id: C8WW11
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS02630
gene id: 521098:AACI_RS02630
uniprot id: C8WSR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I.
messages: Cell membrane
messages: Membrane

521098:AACI RS09670
gene id: 521098:AACI_RS09670
uniprot id: C8WY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

521098:AACI RS10690
gene id: 521098:AACI_RS10690
uniprot id: C8WR05
names: Similarity
messages: Belongs to the manganese catalase family.

521098:AACI RS07035
gene id: 521098:AACI_RS07035
uniprot id: C8WWH4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

521098:AACI RS03360
gene id: 521098:AACI_RS03360
uniprot id: C8WTG9
names: Similarity
messages: Belongs to the peptidase S11 family.

521098:AACI RS03340
gene id: 521098:AACI_RS03340
uniprot id: C8WTG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds a copper B center.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Heme A3.
messages: Membrane

521098:AACI RS01545
gene id: 521098:AACI_RS01545
uniprot id: C8WRD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

521098:AACI RS00885
gene id: 521098:AACI_RS00885
uniprot id: C8WQQ8
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

521098:AACI RS11155
gene id: 521098:AACI_RS11155
uniprot id: C8WR95
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS09640
gene id: 521098:AACI_RS09640
uniprot id: C8WY02
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

521098:AACI RS00795
gene id: 521098:AACI_RS00795
uniprot id: C8WQP1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521098:AACI RS12945
gene id: 521098:AACI_RS12945
uniprot id: C8WTA1
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS05410
gene id: 521098:AACI_RS05410
uniprot id: C8WVJ6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

521098:AACI RS14515
gene id: 521098:AACI_RS14515
uniprot id: C8WV94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

521098:AACI RS01195
gene id: 521098:AACI_RS01195
uniprot id: C8WQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

521098:AACI RS04410
gene id: 521098:AACI_RS04410
uniprot id: C8WUT3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

521098:AACI RS14570
gene id: 521098:AACI_RS14570
uniprot id: C8WVA6
names: Similarity
messages: Belongs to the ParB family.

521098:AACI RS14880
gene id: 521098:AACI_RS14880
uniprot id: C8WYC0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

521098:AACI RS13615
gene id: 521098:AACI_RS13615
uniprot id: C8WU07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

521098:AACI RS02325
gene id: 521098:AACI_RS02325
uniprot id: C8WS67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family. IolA subfamily.
messages: Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
messages: Homotetramer.

521098:AACI RS06700
gene id: 521098:AACI_RS06700
uniprot id: C8WWA8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

521098:AACI RS08715
gene id: 521098:AACI_RS08715
uniprot id: C8WXG0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

521098:AACI RS10055
gene id: 521098:AACI_RS10055
uniprot id: C8WQA2
names: Subcellular Location Annotation
messages: Nucleus

521098:AACI RS01575
gene id: 521098:AACI_RS01575
uniprot id: C8WRE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

521098:AACI RS11865
gene id: 521098:AACI_RS11865
uniprot id: C8WSC1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

521098:AACI RS07680
gene id: 521098:AACI_RS07680
uniprot id: C8WWV1
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

521098:AACI RS07250
gene id: 521098:AACI_RS07250
uniprot id: C8WWL7
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

521098:AACI RS11095
gene id: 521098:AACI_RS11095
uniprot id: C8WR80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS10625
gene id: 521098:AACI_RS10625
uniprot id: C8WQZ2
names: Similarity
messages: Belongs to the EamA transporter family.

521098:AACI RS07355
gene id: 521098:AACI_RS07355
uniprot id: C8WWN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

521098:AACI RS02635
gene id: 521098:AACI_RS02635
uniprot id: C8WSR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

521098:AACI RS01730
gene id: 521098:AACI_RS01730
uniprot id: C8WRH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

521098:AACI RS03455
gene id: 521098:AACI_RS03455
uniprot id: C8WTI7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

521098:AACI RS13655
gene id: 521098:AACI_RS13655
uniprot id: C8WU15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS13470
gene id: 521098:AACI_RS13470
uniprot id: C8WTX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

521098:AACI RS02115
gene id: 521098:AACI_RS02115
uniprot id: C8WS27
names: Similarity
messages: Belongs to the EamA transporter family.

521098:AACI RS02000
gene id: 521098:AACI_RS02000
uniprot id: C8WS04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

521098:AACI RS01905
gene id: 521098:AACI_RS01905
uniprot id: C8WRY4
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

521098:AACI RS01980
gene id: 521098:AACI_RS01980
uniprot id: C8WS00
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

521098:AACI RS15605
gene id: 521098:AACI_RS15605
uniprot id: C8WWS8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

521098:AACI RS07500
gene id: 521098:AACI_RS07500
uniprot id: C8WWR3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

521098:AACI RS12970
gene id: 521098:AACI_RS12970
uniprot id: C8WTA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

521098:AACI RS10270
gene id: 521098:AACI_RS10270
uniprot id: C8WQE5
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS12400
gene id: 521098:AACI_RS12400
uniprot id: C8WSN1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

521098:AACI RS08930
gene id: 521098:AACI_RS08930
uniprot id: C8WXK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

521098:AACI RS07365
gene id: 521098:AACI_RS07365
uniprot id: C8WWP0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

521098:AACI RS06125
gene id: 521098:AACI_RS06125
uniprot id: C8WVZ2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

521098:AACI RS04595
gene id: 521098:AACI_RS04595
uniprot id: C8WUX0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

521098:AACI RS00930
gene id: 521098:AACI_RS00930
uniprot id: C8WQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

521098:AACI RS01950
gene id: 521098:AACI_RS01950
uniprot id: C8WRZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

521098:AACI RS03665
gene id: 521098:AACI_RS03665
uniprot id: C8WTN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521098:AACI RS10285
gene id: 521098:AACI_RS10285
uniprot id: C8WQE8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

521098:AACI RS12670
gene id: 521098:AACI_RS12670
uniprot id: C8WT52
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

521098:AACI RS09545
gene id: 521098:AACI_RS09545
uniprot id: C8WXY3
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

521098:AACI RS13055
gene id: 521098:AACI_RS13055
uniprot id: C8WTP5
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

521098:AACI RS11875
gene id: 521098:AACI_RS11875
uniprot id: C8WSC3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521098:AACI RS12230
gene id: 521098:AACI_RS12230
uniprot id: C8WSJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

521098:AACI RS13090
gene id: 521098:AACI_RS13090
uniprot id: C8WTQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

521098:AACI RS09090
gene id: 521098:AACI_RS09090
uniprot id: C8WXN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

521098:AACI RS04350
gene id: 521098:AACI_RS04350
uniprot id: C8WUS1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS06975
gene id: 521098:AACI_RS06975
uniprot id: C8WWG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

521098:AACI RS04470
gene id: 521098:AACI_RS04470
uniprot id: C8WUU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

521098:AACI RS04900
gene id: 521098:AACI_RS04900
uniprot id: C8WV31
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

521098:AACI RS01035
gene id: 521098:AACI_RS01035
uniprot id: C8WQT9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

521098:AACI RS04820
gene id: 521098:AACI_RS04820
uniprot id: C8WV16
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

521098:AACI RS07855
gene id: 521098:AACI_RS07855
uniprot id: C8WWY6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

521098:AACI RS02400
gene id: 521098:AACI_RS02400
uniprot id: C8WS82
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

521098:AACI RS13200
gene id: 521098:AACI_RS13200
uniprot id: C8WTS4
names: Similarity
messages: Belongs to the asp23 family.

521098:AACI RS15200
gene id: 521098:AACI_RS15200
uniprot id: C8WYJ0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

521098:AACI RS13790
gene id: 521098:AACI_RS13790
uniprot id: C8WUG8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

521098:AACI RS10380
gene id: 521098:AACI_RS10380
uniprot id: C8WQG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

521098:AACI RS10730
gene id: 521098:AACI_RS10730
uniprot id: C8WR13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

521098:AACI RS06070
gene id: 521098:AACI_RS06070
uniprot id: C8WVY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

521098:AACI RS10455
gene id: 521098:AACI_RS10455
uniprot id: C8WQI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

521098:AACI RS00165
gene id: 521098:AACI_RS00165
uniprot id: C8WPY8
names: Cofactor
messages: Can also use Mn(2+) ion.

521098:AACI RS09945
gene id: 521098:AACI_RS09945
uniprot id: C8WQ80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

521098:AACI RS15450
gene id: 521098:AACI_RS15450
uniprot id: C8WYP4
names: Subcellular Location Annotation
messages: Cell membrane

521098:AACI RS03055
gene id: 521098:AACI_RS03055
uniprot id: C8WSZ3
names: Similarity
messages: Belongs to the VapB family.

521098:AACI RS13545
gene id: 521098:AACI_RS13545
uniprot id: C8WTZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

521098:AACI RS03255
gene id: 521098:AACI_RS03255
uniprot id: C8WTE8
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS03725
gene id: 521098:AACI_RS03725
uniprot id: C8WU23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

521098:AACI RS13560
gene id: 521098:AACI_RS13560
uniprot id: C8WTZ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS09080
gene id: 521098:AACI_RS09080
uniprot id: C8WXN5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

521098:AACI RS08550
gene id: 521098:AACI_RS08550
uniprot id: C8WXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

521098:AACI RS02300
gene id: 521098:AACI_RS02300
uniprot id: C8WS61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

521098:AACI RS11860
gene id: 521098:AACI_RS11860
uniprot id: C8WSC0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

521098:AACI RS02075
gene id: 521098:AACI_RS02075
uniprot id: C8WS19
names: Similarity
messages: Belongs to the SAICAR synthetase family.

521098:AACI RS00080
gene id: 521098:AACI_RS00080
uniprot id: C8WPX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

521098:AACI RS02070
gene id: 521098:AACI_RS02070
uniprot id: C8WS18
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

521098:AACI RS00035
gene id: 521098:AACI_RS00035
uniprot id: C8WXT2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

521098:AACI RS10620
gene id: 521098:AACI_RS10620
uniprot id: C8WQZ1
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

521098:AACI RS03770
gene id: 521098:AACI_RS03770
uniprot id: C8WU32
names: Subcellular Location Annotation
messages: Membrane

521098:AACI RS00620
gene id: 521098:AACI_RS00620
uniprot id: C8WQK6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

521098:AACI RS14595
gene id: 521098:AACI_RS14595
uniprot id: C8WVB1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521098:AACI RS12650
gene id: 521098:AACI_RS12650
uniprot id: C8WT48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

521098:AACI RS09540
gene id: 521098:AACI_RS09540
uniprot id: C8WXY2
names: Similarity
messages: Belongs to the ThiD family.

521098:AACI RS09465
gene id: 521098:AACI_RS09465
uniprot id: C8WXW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

521098:AACI RS06465
gene id: 521098:AACI_RS06465
uniprot id: C8WW60
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

521098:AACI RS04575
gene id: 521098:AACI_RS04575
uniprot id: C8WUW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521098:AACI RS09365
gene id: 521098:AACI_RS09365
uniprot id: C8WXU6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

521098:AACI RS01040
gene id: 521098:AACI_RS01040
uniprot id: C8WQU0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

521098:AACI RS11280
gene id: 521098:AACI_RS11280
uniprot id: C8WRM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.