521095:APAR RS03550
gene id: 521095:APAR_RS03550
uniprot id: C8WAI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

521095:APAR RS05175
gene id: 521095:APAR_RS05175
uniprot id: C8W7J6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

521095:APAR RS04680
gene id: 521095:APAR_RS04680
uniprot id: C8W7A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS05120
gene id: 521095:APAR_RS05120
uniprot id: C8W7I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

521095:APAR RS05225
gene id: 521095:APAR_RS05225
uniprot id: C8W7K6
names: Similarity
messages: Belongs to the UPF0237 family.

521095:APAR RS06385
gene id: 521095:APAR_RS06385
uniprot id: C8W881
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS07380
gene id: 521095:APAR_RS07380
uniprot id: C8W8E2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

521095:APAR RS03575
gene id: 521095:APAR_RS03575
uniprot id: C8WAI7
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

521095:APAR RS04320
gene id: 521095:APAR_RS04320
uniprot id: C8W730
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

521095:APAR RS04415
gene id: 521095:APAR_RS04415
uniprot id: C8W749
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

521095:APAR RS00425
gene id: 521095:APAR_RS00425
uniprot id: C8W8S6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

521095:APAR RS02430
gene id: 521095:APAR_RS02430
uniprot id: C8W9W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS03175
gene id: 521095:APAR_RS03175
uniprot id: C8WAA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

521095:APAR RS00160
gene id: 521095:APAR_RS00160
uniprot id: C8W8M6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

521095:APAR RS02010
gene id: 521095:APAR_RS02010
uniprot id: C8W9N2
names: Similarity
messages: Belongs to the asp23 family.

521095:APAR RS00565
gene id: 521095:APAR_RS00565
uniprot id: C8W8V6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

521095:APAR RS02060
gene id: 521095:APAR_RS02060
uniprot id: C8W9P2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

521095:APAR RS00245
gene id: 521095:APAR_RS00245
uniprot id: C8W8P2
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS04025
gene id: 521095:APAR_RS04025
uniprot id: C8W6X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

521095:APAR RS06025
gene id: 521095:APAR_RS06025
uniprot id: C8W815
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

521095:APAR RS01320
gene id: 521095:APAR_RS01320
uniprot id: C8W995
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

521095:APAR RS00015
gene id: 521095:APAR_RS00015
uniprot id: C8W8K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

521095:APAR RS05365
gene id: 521095:APAR_RS05365
uniprot id: C8W7N3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

521095:APAR RS06645
gene id: 521095:APAR_RS06645
uniprot id: C8W8C9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

521095:APAR RS02640
gene id: 521095:APAR_RS02640
uniprot id: C8WA06
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

521095:APAR RS02535
gene id: 521095:APAR_RS02535
uniprot id: C8W9Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

521095:APAR RS00870
gene id: 521095:APAR_RS00870
uniprot id: C8W912
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS03335
gene id: 521095:APAR_RS03335
uniprot id: C8WAD9
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

521095:APAR RS03625
gene id: 521095:APAR_RS03625
uniprot id: C8WAJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

521095:APAR RS00155
gene id: 521095:APAR_RS00155
uniprot id: C8W8M5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

521095:APAR RS06400
gene id: 521095:APAR_RS06400
uniprot id: C8W884
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

521095:APAR RS04800
gene id: 521095:APAR_RS04800
uniprot id: C8W7C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

521095:APAR RS02410
gene id: 521095:APAR_RS02410
uniprot id: C8W9W2
names: Similarity
messages: Belongs to the asp23 family.

521095:APAR RS03725
gene id: 521095:APAR_RS03725
uniprot id: C8WAL4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

521095:APAR RS05990
gene id: 521095:APAR_RS05990
uniprot id: C8W809
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

521095:APAR RS06990
gene id: 521095:APAR_RS06990
uniprot id: C8W8J3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

521095:APAR RS04385
gene id: 521095:APAR_RS04385
uniprot id: C8W743
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

521095:APAR RS03405
gene id: 521095:APAR_RS03405
uniprot id: C8WAF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521095:APAR RS05795
gene id: 521095:APAR_RS05795
uniprot id: C8W7X0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

521095:APAR RS01560
gene id: 521095:APAR_RS01560
uniprot id: C8W9E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

521095:APAR RS03900
gene id: 521095:APAR_RS03900
uniprot id: C8WAP8
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS01525
gene id: 521095:APAR_RS01525
uniprot id: C8W9D7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

521095:APAR RS02620
gene id: 521095:APAR_RS02620
uniprot id: C8WA02
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS00415
gene id: 521095:APAR_RS00415
uniprot id: C8W8S4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

521095:APAR RS01150
gene id: 521095:APAR_RS01150
uniprot id: C8W962
names: Similarity
messages: Belongs to the peptidase S51 family.

521095:APAR RS01000
gene id: 521095:APAR_RS01000
uniprot id: C8W937
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

521095:APAR RS02530
gene id: 521095:APAR_RS02530
uniprot id: C8W9Y6
names: Similarity
messages: Belongs to the YggT family.

521095:APAR RS02440
gene id: 521095:APAR_RS02440
uniprot id: C8W9W8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS06630
gene id: 521095:APAR_RS06630
uniprot id: C8W8C6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

521095:APAR RS05935
gene id: 521095:APAR_RS05935
uniprot id: C8W7Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

521095:APAR RS02475
gene id: 521095:APAR_RS02475
uniprot id: C8W9X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

521095:APAR RS01845
gene id: 521095:APAR_RS01845
uniprot id: C8W9J9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

521095:APAR RS01635
gene id: 521095:APAR_RS01635
uniprot id: C8W9F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

521095:APAR RS02215
gene id: 521095:APAR_RS02215
uniprot id: C8W9S2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

521095:APAR RS00965
gene id: 521095:APAR_RS00965
uniprot id: C8W930
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

521095:APAR RS00960
gene id: 521095:APAR_RS00960
uniprot id: C8W929
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

521095:APAR RS02750
gene id: 521095:APAR_RS02750
uniprot id: C8WA26
names: Similarity
messages: Belongs to the leucine-binding protein family.

521095:APAR RS00625
gene id: 521095:APAR_RS00625
uniprot id: C8W8W7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

521095:APAR RS00525
gene id: 521095:APAR_RS00525
uniprot id: C8W8U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

521095:APAR RS05860
gene id: 521095:APAR_RS05860
uniprot id: C8W7Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

521095:APAR RS03330
gene id: 521095:APAR_RS03330
uniprot id: C8WAD8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

521095:APAR RS06735
gene id: 521095:APAR_RS06735
uniprot id: C8W8E7
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS00240
gene id: 521095:APAR_RS00240
uniprot id: C8W8P1
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

521095:APAR RS05800
gene id: 521095:APAR_RS05800
uniprot id: C8W7X1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

521095:APAR RS00200
gene id: 521095:APAR_RS00200
uniprot id: C8W8N4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

521095:APAR RS00985
gene id: 521095:APAR_RS00985
uniprot id: C8W934
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

521095:APAR RS05905
gene id: 521095:APAR_RS05905
uniprot id: C8W7Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

521095:APAR RS05465
gene id: 521095:APAR_RS05465
uniprot id: C8W7Q3
names: Subcellular Location Annotation
messages: Cytoplasm

521095:APAR RS06815
gene id: 521095:APAR_RS06815
uniprot id: C8W8G3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

521095:APAR RS01800
gene id: 521095:APAR_RS01800
uniprot id: C8W9J1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

521095:APAR RS01770
gene id: 521095:APAR_RS01770
uniprot id: C8W9I6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS00605
gene id: 521095:APAR_RS00605
uniprot id: C8W8W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

521095:APAR RS05210
gene id: 521095:APAR_RS05210
uniprot id: C8W7K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

521095:APAR RS05560
gene id: 521095:APAR_RS05560
uniprot id: C8W7S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521095:APAR RS04565
gene id: 521095:APAR_RS04565
uniprot id: C8W779
names: Subcellular Location Annotation
messages: Cytoplasm

521095:APAR RS02255
gene id: 521095:APAR_RS02255
uniprot id: C8W9T1
names: Similarity
messages: Belongs to the CsoR family.

521095:APAR RS04375
gene id: 521095:APAR_RS04375
uniprot id: C8W741
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

521095:APAR RS02555
gene id: 521095:APAR_RS02555
uniprot id: C8W9Z1
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS03955
gene id: 521095:APAR_RS03955
uniprot id: C8WAQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

521095:APAR RS02725
gene id: 521095:APAR_RS02725
uniprot id: C8WA21
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

521095:APAR RS04455
gene id: 521095:APAR_RS04455
uniprot id: C8W757
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

521095:APAR RS00535
gene id: 521095:APAR_RS00535
uniprot id: C8W8V0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

521095:APAR RS05700
gene id: 521095:APAR_RS05700
uniprot id: C8W7V0
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS02740
gene id: 521095:APAR_RS02740
uniprot id: C8WA24
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS00020
gene id: 521095:APAR_RS00020
uniprot id: C8W8K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

521095:APAR RS03950
gene id: 521095:APAR_RS03950
uniprot id: C8WAQ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

521095:APAR RS02035
gene id: 521095:APAR_RS02035
uniprot id: C8W9N7
names: Similarity
messages: Belongs to the peptidase M18 family.

521095:APAR RS04745
gene id: 521095:APAR_RS04745
uniprot id: C8W7B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

521095:APAR RS01600
gene id: 521095:APAR_RS01600
uniprot id: C8W9F2
names: Similarity
messages: Belongs to the peptidase A24 family.

521095:APAR RS04315
gene id: 521095:APAR_RS04315
uniprot id: C8W729
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

521095:APAR RS05205
gene id: 521095:APAR_RS05205
uniprot id: C8W7K2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

521095:APAR RS04840
gene id: 521095:APAR_RS04840
uniprot id: C8W7D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

521095:APAR RS03465
gene id: 521095:APAR_RS03465
uniprot id: C8WAG5
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS03375
gene id: 521095:APAR_RS03375
uniprot id: C8WAE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

521095:APAR RS06185
gene id: 521095:APAR_RS06185
uniprot id: C8W843
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

521095:APAR RS03985
gene id: 521095:APAR_RS03985
uniprot id: C8WAR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

521095:APAR RS06075
gene id: 521095:APAR_RS06075
uniprot id: C8W821
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS06070
gene id: 521095:APAR_RS06070
uniprot id: C8W820
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS01665
gene id: 521095:APAR_RS01665
uniprot id: C8W9G5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

521095:APAR RS07130
gene id: 521095:APAR_RS07130
uniprot id: C8WAC8
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS00595
gene id: 521095:APAR_RS00595
uniprot id: C8W8W2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

521095:APAR RS04245
gene id: 521095:APAR_RS04245
uniprot id: C8W715
names: Similarity
messages: Belongs to the ribF family.

521095:APAR RS02490
gene id: 521095:APAR_RS02490
uniprot id: C8W9X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS01745
gene id: 521095:APAR_RS01745
uniprot id: C8W9I1
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

521095:APAR RS00330
gene id: 521095:APAR_RS00330
uniprot id: C8W8Q8
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

521095:APAR RS03605
gene id: 521095:APAR_RS03605
uniprot id: C8WAJ3
names: Similarity
messages: Belongs to the DprA/Smf family.

521095:APAR RS00295
gene id: 521095:APAR_RS00295
uniprot id: C8W8Q1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

521095:APAR RS05855
gene id: 521095:APAR_RS05855
uniprot id: C8W7Y2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

521095:APAR RS04060
gene id: 521095:APAR_RS04060
uniprot id: C8W6X9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

521095:APAR RS00065
gene id: 521095:APAR_RS00065
uniprot id: C8W8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

521095:APAR RS05415
gene id: 521095:APAR_RS05415
uniprot id: C8W7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

521095:APAR RS04600
gene id: 521095:APAR_RS04600
uniprot id: C8W787
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

521095:APAR RS00300
gene id: 521095:APAR_RS00300
uniprot id: C8W8Q2
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

521095:APAR RS05660
gene id: 521095:APAR_RS05660
uniprot id: C8W7U2
names: Similarity
messages: Belongs to the glutamine synthetase family.

521095:APAR RS05945
gene id: 521095:APAR_RS05945
uniprot id: C8W801
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

521095:APAR RS04835
gene id: 521095:APAR_RS04835
uniprot id: C8W7C9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

521095:APAR RS00735
gene id: 521095:APAR_RS00735
uniprot id: C8W8Y6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

521095:APAR RS00580
gene id: 521095:APAR_RS00580
uniprot id: C8W8V9
names: Similarity
messages: In the C-terminal section; belongs to the DHPS family.

521095:APAR RS05930
gene id: 521095:APAR_RS05930
uniprot id: C8W7Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

521095:APAR RS05325
gene id: 521095:APAR_RS05325
uniprot id: C8W7M6
names: Subcellular Location Annotation
messages: Cell membrane

521095:APAR RS04370
gene id: 521095:APAR_RS04370
uniprot id: C8W740
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

521095:APAR RS05670
gene id: 521095:APAR_RS05670
uniprot id: C8W7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

521095:APAR RS03230
gene id: 521095:APAR_RS03230
uniprot id: C8WAB8
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS04675
gene id: 521095:APAR_RS04675
uniprot id: C8W7A1
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS06635
gene id: 521095:APAR_RS06635
uniprot id: C8W8C7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

521095:APAR RS02360
gene id: 521095:APAR_RS02360
uniprot id: C8W9V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

521095:APAR RS04140
gene id: 521095:APAR_RS04140
uniprot id: C8W6Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

521095:APAR RS05395
gene id: 521095:APAR_RS05395
uniprot id: C8W7N9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

521095:APAR RS05330
gene id: 521095:APAR_RS05330
uniprot id: C8W7M7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

521095:APAR RS02265
gene id: 521095:APAR_RS02265
uniprot id: C8W9T3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

521095:APAR RS03270
gene id: 521095:APAR_RS03270
uniprot id: C8WAC6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

521095:APAR RS03415
gene id: 521095:APAR_RS03415
uniprot id: C8WAF6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS00145
gene id: 521095:APAR_RS00145
uniprot id: C8W8M4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

521095:APAR RS03945
gene id: 521095:APAR_RS03945
uniprot id: C8WAQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

521095:APAR RS04150
gene id: 521095:APAR_RS04150
uniprot id: C8W6Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

521095:APAR RS04705
gene id: 521095:APAR_RS04705
uniprot id: C8W7A5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

521095:APAR RS04505
gene id: 521095:APAR_RS04505
uniprot id: C8W767
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

521095:APAR RS06670
gene id: 521095:APAR_RS06670
uniprot id: C8W8D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

521095:APAR RS05370
gene id: 521095:APAR_RS05370
uniprot id: C8W7N4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

521095:APAR RS06715
gene id: 521095:APAR_RS06715
uniprot id: C8W8E3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

521095:APAR RS03815
gene id: 521095:APAR_RS03815
uniprot id: C8WAN1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

521095:APAR RS02425
gene id: 521095:APAR_RS02425
uniprot id: C8W9W5
names: Similarity
messages: Belongs to the TlyA family.

521095:APAR RS04160
gene id: 521095:APAR_RS04160
uniprot id: C8W6Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

521095:APAR RS04540
gene id: 521095:APAR_RS04540
uniprot id: C8W774
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS06515
gene id: 521095:APAR_RS06515
uniprot id: C8W8A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

521095:APAR RS03260
gene id: 521095:APAR_RS03260
uniprot id: C8WAC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS00545
gene id: 521095:APAR_RS00545
uniprot id: C8W8V2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

521095:APAR RS02405
gene id: 521095:APAR_RS02405
uniprot id: C8W9W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

521095:APAR RS05840
gene id: 521095:APAR_RS05840
uniprot id: C8W7X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

521095:APAR RS02795
gene id: 521095:APAR_RS02795
uniprot id: C8WA35
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS03110
gene id: 521095:APAR_RS03110
uniprot id: C8WA97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

521095:APAR RS04445
gene id: 521095:APAR_RS04445
uniprot id: C8W755
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS00650
gene id: 521095:APAR_RS00650
uniprot id: C8W8X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

521095:APAR RS05060
gene id: 521095:APAR_RS05060
uniprot id: C8W7H3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

521095:APAR RS02390
gene id: 521095:APAR_RS02390
uniprot id: C8W9V8
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS02445
gene id: 521095:APAR_RS02445
uniprot id: C8W9W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

521095:APAR RS04865
gene id: 521095:APAR_RS04865
uniprot id: C8W7D5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

521095:APAR RS02500
gene id: 521095:APAR_RS02500
uniprot id: C8W9Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

521095:APAR RS04985
gene id: 521095:APAR_RS04985
uniprot id: C8W7F9
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS02110
gene id: 521095:APAR_RS02110
uniprot id: C8W9Q2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

521095:APAR RS04300
gene id: 521095:APAR_RS04300
uniprot id: C8W726
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS03660
gene id: 521095:APAR_RS03660
uniprot id: C8WAK4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

521095:APAR RS00335
gene id: 521095:APAR_RS00335
uniprot id: C8W8Q9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

521095:APAR RS06560
gene id: 521095:APAR_RS06560
uniprot id: C8W8B5
names: Similarity
messages: Belongs to the DapA family.

521095:APAR RS06095
gene id: 521095:APAR_RS06095
uniprot id: C8W825
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

521095:APAR RS04975
gene id: 521095:APAR_RS04975
uniprot id: C8W7F7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

521095:APAR RS02790
gene id: 521095:APAR_RS02790
uniprot id: C8WA34
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

521095:APAR RS06255
gene id: 521095:APAR_RS06255
uniprot id: C8W856
names: Similarity
messages: Belongs to the XFP family.

521095:APAR RS05440
gene id: 521095:APAR_RS05440
uniprot id: C8W7P8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

521095:APAR RS03220
gene id: 521095:APAR_RS03220
uniprot id: C8WAB6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

521095:APAR RS03760
gene id: 521095:APAR_RS03760
uniprot id: C8WAM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

521095:APAR RS00495
gene id: 521095:APAR_RS00495
uniprot id: C8W8U2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

521095:APAR RS04805
gene id: 521095:APAR_RS04805
uniprot id: C8W7C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521095:APAR RS03585
gene id: 521095:APAR_RS03585
uniprot id: C8WAI9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

521095:APAR RS05805
gene id: 521095:APAR_RS05805
uniprot id: C8W7X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

521095:APAR RS01555
gene id: 521095:APAR_RS01555
uniprot id: C8W9E3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

521095:APAR RS07025
gene id: 521095:APAR_RS07025
uniprot id: C8W8J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

521095:APAR RS03200
gene id: 521095:APAR_RS03200
uniprot id: C8WAB2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

521095:APAR RS03890
gene id: 521095:APAR_RS03890
uniprot id: C8WAP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

521095:APAR RS03425
gene id: 521095:APAR_RS03425
uniprot id: C8WAF7
names: Subcellular Location Annotation
messages: Cell membrane

521095:APAR RS00560
gene id: 521095:APAR_RS00560
uniprot id: C8W8V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

521095:APAR RS01350
gene id: 521095:APAR_RS01350
uniprot id: C8W9A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

521095:APAR RS01280
gene id: 521095:APAR_RS01280
uniprot id: C8W988
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

521095:APAR RS01790
gene id: 521095:APAR_RS01790
uniprot id: C8W9I9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

521095:APAR RS06575
gene id: 521095:APAR_RS06575
uniprot id: C8W8B8
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS02670
gene id: 521095:APAR_RS02670
uniprot id: C8WA12
names: Similarity
messages: Belongs to the RecJ family.

521095:APAR RS01625
gene id: 521095:APAR_RS01625
uniprot id: C8W9F7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

521095:APAR RS03490
gene id: 521095:APAR_RS03490
uniprot id: C8WAH0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

521095:APAR RS04875
gene id: 521095:APAR_RS04875
uniprot id: C8W7D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

521095:APAR RS05950
gene id: 521095:APAR_RS05950
uniprot id: C8W802
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

521095:APAR RS05600
gene id: 521095:APAR_RS05600
uniprot id: C8W7T0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

521095:APAR RS01270
gene id: 521095:APAR_RS01270
uniprot id: C8W986
names: Similarity
messages: Belongs to the carbamate kinase family.

521095:APAR RS02350
gene id: 521095:APAR_RS02350
uniprot id: C8W9V0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

521095:APAR RS03515
gene id: 521095:APAR_RS03515
uniprot id: C8WAH5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

521095:APAR RS01925
gene id: 521095:APAR_RS01925
uniprot id: C8W9L5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

521095:APAR RS06775
gene id: 521095:APAR_RS06775
uniprot id: C8W8F5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

521095:APAR RS02615
gene id: 521095:APAR_RS02615
uniprot id: C8WA01
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS02175
gene id: 521095:APAR_RS02175
uniprot id: C8W9R4
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS06380
gene id: 521095:APAR_RS06380
uniprot id: C8W880
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

521095:APAR RS05995
gene id: 521095:APAR_RS05995
uniprot id: C8W810
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

521095:APAR RS05640
gene id: 521095:APAR_RS05640
uniprot id: C8W7T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

521095:APAR RS06010
gene id: 521095:APAR_RS06010
uniprot id: C8W813
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

521095:APAR RS02295
gene id: 521095:APAR_RS02295
uniprot id: C8W9T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521095:APAR RS03655
gene id: 521095:APAR_RS03655
uniprot id: C8WAK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

521095:APAR RS05610
gene id: 521095:APAR_RS05610
uniprot id: C8W7T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

521095:APAR RS07255
gene id: 521095:APAR_RS07255
uniprot id: C8W7Y6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

521095:APAR RS00450
gene id: 521095:APAR_RS00450
uniprot id: C8W8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

521095:APAR RS03235
gene id: 521095:APAR_RS03235
uniprot id: C8WAB9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS04265
gene id: 521095:APAR_RS04265
uniprot id: C8W719
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

521095:APAR RS00975
gene id: 521095:APAR_RS00975
uniprot id: C8W932
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

521095:APAR RS03150
gene id: 521095:APAR_RS03150
uniprot id: C8WAA3
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

521095:APAR RS06115
gene id: 521095:APAR_RS06115
uniprot id: C8W829
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

521095:APAR RS02180
gene id: 521095:APAR_RS02180
uniprot id: C8W9R5
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS05500
gene id: 521095:APAR_RS05500
uniprot id: C8W7R0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

521095:APAR RS03770
gene id: 521095:APAR_RS03770
uniprot id: C8WAM3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

521095:APAR RS04405
gene id: 521095:APAR_RS04405
uniprot id: C8W747
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

521095:APAR RS06105
gene id: 521095:APAR_RS06105
uniprot id: C8W827
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

521095:APAR RS06655
gene id: 521095:APAR_RS06655
uniprot id: C8W8D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

521095:APAR RS05575
gene id: 521095:APAR_RS05575
uniprot id: C8W7S5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

521095:APAR RS05025
gene id: 521095:APAR_RS05025
uniprot id: C8W7G6
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.

521095:APAR RS04965
gene id: 521095:APAR_RS04965
uniprot id: C8W7F5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS03145
gene id: 521095:APAR_RS03145
uniprot id: C8WAA2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

521095:APAR RS02200
gene id: 521095:APAR_RS02200
uniprot id: C8W9R9
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

521095:APAR RS00905
gene id: 521095:APAR_RS00905
uniprot id: C8W918
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS00990
gene id: 521095:APAR_RS00990
uniprot id: C8W935
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

521095:APAR RS01475
gene id: 521095:APAR_RS01475
uniprot id: C8W9C7
names: Similarity
messages: Belongs to the KdgT transporter family.

521095:APAR RS01170
gene id: 521095:APAR_RS01170
uniprot id: C8W966
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

521095:APAR RS03160
gene id: 521095:APAR_RS03160
uniprot id: C8WAA5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS01210
gene id: 521095:APAR_RS01210
uniprot id: C8W974
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS02785
gene id: 521095:APAR_RS02785
uniprot id: C8WA33
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

521095:APAR RS01735
gene id: 521095:APAR_RS01735
uniprot id: C8W9H9
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS04120
gene id: 521095:APAR_RS04120
uniprot id: C8W6Z1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

521095:APAR RS06140
gene id: 521095:APAR_RS06140
uniprot id: C8W834
names: Similarity
messages: Belongs to the nitroreductase family.

521095:APAR RS02290
gene id: 521095:APAR_RS02290
uniprot id: C8W9T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521095:APAR RS02675
gene id: 521095:APAR_RS02675
uniprot id: C8WA13
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

521095:APAR RS01840
gene id: 521095:APAR_RS01840
uniprot id: C8W9J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

521095:APAR RS02345
gene id: 521095:APAR_RS02345
uniprot id: C8W9U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

521095:APAR RS06755
gene id: 521095:APAR_RS06755
uniprot id: C8W8F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

521095:APAR RS05815
gene id: 521095:APAR_RS05815
uniprot id: C8W7X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

521095:APAR RS06525
gene id: 521095:APAR_RS06525
uniprot id: C8W8A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

521095:APAR RS01820
gene id: 521095:APAR_RS01820
uniprot id: C8W9J5
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS00430
gene id: 521095:APAR_RS00430
uniprot id: C8W8S7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

521095:APAR RS04900
gene id: 521095:APAR_RS04900
uniprot id: C8W7E2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit.

521095:APAR RS04185
gene id: 521095:APAR_RS04185
uniprot id: C8W704
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

521095:APAR RS01300
gene id: 521095:APAR_RS01300
uniprot id: C8W992
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

521095:APAR RS03735
gene id: 521095:APAR_RS03735
uniprot id: C8WAL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

521095:APAR RS03305
gene id: 521095:APAR_RS03305
uniprot id: C8WAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

521095:APAR RS04770
gene id: 521095:APAR_RS04770
uniprot id: C8W7B6
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

521095:APAR RS00880
gene id: 521095:APAR_RS00880
uniprot id: C8W914
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

521095:APAR RS00345
gene id: 521095:APAR_RS00345
uniprot id: C8W8R1
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

521095:APAR RS04630
gene id: 521095:APAR_RS04630
uniprot id: C8W793
names: Similarity
messages: Belongs to the IMPACT family.

521095:APAR RS05555
gene id: 521095:APAR_RS05555
uniprot id: C8W7S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

521095:APAR RS01570
gene id: 521095:APAR_RS01570
uniprot id: C8W9E6
names: Similarity
messages: Belongs to the asparaginase 1 family.

521095:APAR RS04740
gene id: 521095:APAR_RS04740
uniprot id: C8W7B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

521095:APAR RS04590
gene id: 521095:APAR_RS04590
uniprot id: C8W784
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

521095:APAR RS04145
gene id: 521095:APAR_RS04145
uniprot id: C8W6Z6
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

521095:APAR RS00035
gene id: 521095:APAR_RS00035
uniprot id: C8W8K8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

521095:APAR RS05925
gene id: 521095:APAR_RS05925
uniprot id: C8W7Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

521095:APAR RS01975
gene id: 521095:APAR_RS01975
uniprot id: C8W9M5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

521095:APAR RS04650
gene id: 521095:APAR_RS04650
uniprot id: C8W797
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

521095:APAR RS06130
gene id: 521095:APAR_RS06130
uniprot id: C8W832
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

521095:APAR RS01785
gene id: 521095:APAR_RS01785
uniprot id: C8W9I8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

521095:APAR RS05135
gene id: 521095:APAR_RS05135
uniprot id: C8W7I8
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS04105
gene id: 521095:APAR_RS04105
uniprot id: C8W6Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

521095:APAR RS03595
gene id: 521095:APAR_RS03595
uniprot id: C8WAJ1
names: Similarity
messages: Belongs to the UPF0102 family.

521095:APAR RS05525
gene id: 521095:APAR_RS05525
uniprot id: C8W7R5
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS06650
gene id: 521095:APAR_RS06650
uniprot id: C8W8D0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS03895
gene id: 521095:APAR_RS03895
uniprot id: C8WAP7
names: Similarity
messages: Belongs to the peptidase C40 family.

521095:APAR RS02210
gene id: 521095:APAR_RS02210
uniprot id: C8W9S1
names: Similarity
messages: Belongs to the glutamine synthetase family.

521095:APAR RS03360
gene id: 521095:APAR_RS03360
uniprot id: C8WAE4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

521095:APAR RS05595
gene id: 521095:APAR_RS05595
uniprot id: C8W7S9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

521095:APAR RS05215
gene id: 521095:APAR_RS05215
uniprot id: C8W7K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

521095:APAR RS03345
gene id: 521095:APAR_RS03345
uniprot id: C8WAE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

521095:APAR RS00590
gene id: 521095:APAR_RS00590
uniprot id: C8W8W1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS05455
gene id: 521095:APAR_RS05455
uniprot id: C8W7Q1
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS05235
gene id: 521095:APAR_RS05235
uniprot id: C8W7K8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

521095:APAR RS05335
gene id: 521095:APAR_RS05335
uniprot id: C8W7M8
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

521095:APAR RS01685
gene id: 521095:APAR_RS01685
uniprot id: C8W9G9
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS00970
gene id: 521095:APAR_RS00970
uniprot id: C8W931
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

521095:APAR RS05005
gene id: 521095:APAR_RS05005
uniprot id: C8W7G3
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

521095:APAR RS04610
gene id: 521095:APAR_RS04610
uniprot id: C8W789
names: Similarity
messages: Belongs to the peptidase C1 family.

521095:APAR RS02525
gene id: 521095:APAR_RS02525
uniprot id: C8W9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

521095:APAR RS00025
gene id: 521095:APAR_RS00025
uniprot id: C8W8K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

521095:APAR RS01465
gene id: 521095:APAR_RS01465
uniprot id: C8W9C5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

521095:APAR RS04885
gene id: 521095:APAR_RS04885
uniprot id: C8W7D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

521095:APAR RS05845
gene id: 521095:APAR_RS05845
uniprot id: C8W7Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

521095:APAR RS06435
gene id: 521095:APAR_RS06435
uniprot id: C8W891
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

521095:APAR RS02195
gene id: 521095:APAR_RS02195
uniprot id: C8W9R8
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS00770
gene id: 521095:APAR_RS00770
uniprot id: C8W8Z3
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS01870
gene id: 521095:APAR_RS01870
uniprot id: C8W9K4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

521095:APAR RS04045
gene id: 521095:APAR_RS04045
uniprot id: C8W6X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

521095:APAR RS02165
gene id: 521095:APAR_RS02165
uniprot id: C8W9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

521095:APAR RS04450
gene id: 521095:APAR_RS04450
uniprot id: C8W756
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

521095:APAR RS02260
gene id: 521095:APAR_RS02260
uniprot id: C8W9T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

521095:APAR RS02485
gene id: 521095:APAR_RS02485
uniprot id: C8W9X7
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS04130
gene id: 521095:APAR_RS04130
uniprot id: C8W6Z3
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS06690
gene id: 521095:APAR_RS06690
uniprot id: C8W8D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

521095:APAR RS04050
gene id: 521095:APAR_RS04050
uniprot id: C8W6X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

521095:APAR RS02650
gene id: 521095:APAR_RS02650
uniprot id: C8WA08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

521095:APAR RS06840
gene id: 521095:APAR_RS06840
uniprot id: C8W8G8
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS05405
gene id: 521095:APAR_RS05405
uniprot id: C8W7P1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

521095:APAR RS03765
gene id: 521095:APAR_RS03765
uniprot id: C8WAM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

521095:APAR RS04070
gene id: 521095:APAR_RS04070
uniprot id: C8W6Y1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

521095:APAR RS05165
gene id: 521095:APAR_RS05165
uniprot id: C8W7J4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

521095:APAR RS03205
gene id: 521095:APAR_RS03205
uniprot id: C8WAB3
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

521095:APAR RS05305
gene id: 521095:APAR_RS05305
uniprot id: C8W7M2
names: Similarity
messages: Belongs to the GSP E family.

521095:APAR RS00645
gene id: 521095:APAR_RS00645
uniprot id: C8W8X1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

521095:APAR RS03740
gene id: 521095:APAR_RS03740
uniprot id: C8WAL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

521095:APAR RS05850
gene id: 521095:APAR_RS05850
uniprot id: C8W7Y1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

521095:APAR RS06725
gene id: 521095:APAR_RS06725
uniprot id: C8W8E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

521095:APAR RS04055
gene id: 521095:APAR_RS04055
uniprot id: C8W6X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

521095:APAR RS03795
gene id: 521095:APAR_RS03795
uniprot id: C8WAM8
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS03965
gene id: 521095:APAR_RS03965
uniprot id: C8WAR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

521095:APAR RS01285
gene id: 521095:APAR_RS01285
uniprot id: C8W989
names: Similarity
messages: Belongs to the RutC family.

521095:APAR RS00600
gene id: 521095:APAR_RS00600
uniprot id: C8W8W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

521095:APAR RS05425
gene id: 521095:APAR_RS05425
uniprot id: C8W7P5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

521095:APAR RS03650
gene id: 521095:APAR_RS03650
uniprot id: C8WAK2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS04020
gene id: 521095:APAR_RS04020
uniprot id: C8W6X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

521095:APAR RS04755
gene id: 521095:APAR_RS04755
uniprot id: C8W7B3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

521095:APAR RS02595
gene id: 521095:APAR_RS02595
uniprot id: C8W9Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521095:APAR RS04180
gene id: 521095:APAR_RS04180
uniprot id: C8W703
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

521095:APAR RS02415
gene id: 521095:APAR_RS02415
uniprot id: C8W9W3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

521095:APAR RS02480
gene id: 521095:APAR_RS02480
uniprot id: C8W9X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

521095:APAR RS07005
gene id: 521095:APAR_RS07005
uniprot id: C8W8J5
names: Similarity
messages: Belongs to the ParB family.

521095:APAR RS02590
gene id: 521095:APAR_RS02590
uniprot id: C8W9Z6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

521095:APAR RS03975
gene id: 521095:APAR_RS03975
uniprot id: C8WAR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

521095:APAR RS02185
gene id: 521095:APAR_RS02185
uniprot id: C8W9R6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

521095:APAR RS06740
gene id: 521095:APAR_RS06740
uniprot id: C8W8E8
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS06030
gene id: 521095:APAR_RS06030
uniprot id: C8W816
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

521095:APAR RS03485
gene id: 521095:APAR_RS03485
uniprot id: C8WAG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

521095:APAR RS01640
gene id: 521095:APAR_RS01640
uniprot id: C8W9G0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

521095:APAR RS06940
gene id: 521095:APAR_RS06940
uniprot id: C8W8I4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

521095:APAR RS01335
gene id: 521095:APAR_RS01335
uniprot id: C8W998
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

521095:APAR RS04810
gene id: 521095:APAR_RS04810
uniprot id: C8W7C4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

521095:APAR RS00755
gene id: 521095:APAR_RS00755
uniprot id: C8W8Z0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

521095:APAR RS06015
gene id: 521095:APAR_RS06015
uniprot id: C8W814
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

521095:APAR RS00390
gene id: 521095:APAR_RS00390
uniprot id: C8W8R9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

521095:APAR RS06200
gene id: 521095:APAR_RS06200
uniprot id: C8W846
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS02355
gene id: 521095:APAR_RS02355
uniprot id: C8W9V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

521095:APAR RS03560
gene id: 521095:APAR_RS03560
uniprot id: C8WAI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

521095:APAR RS03450
gene id: 521095:APAR_RS03450
uniprot id: C8WAG2
names: Similarity
messages: Belongs to the MreC family.

521095:APAR RS05445
gene id: 521095:APAR_RS05445
uniprot id: C8W7P9
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

521095:APAR RS05885
gene id: 521095:APAR_RS05885
uniprot id: C8W7Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

521095:APAR RS06395
gene id: 521095:APAR_RS06395
uniprot id: C8W883
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

521095:APAR RS05785
gene id: 521095:APAR_RS05785
uniprot id: C8W7W8
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS04215
gene id: 521095:APAR_RS04215
uniprot id: C8W710
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS04465
gene id: 521095:APAR_RS04465
uniprot id: C8W759
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

521095:APAR RS04310
gene id: 521095:APAR_RS04310
uniprot id: C8W728
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

521095:APAR RS05825
gene id: 521095:APAR_RS05825
uniprot id: C8W7X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

521095:APAR RS03565
gene id: 521095:APAR_RS03565
uniprot id: C8WAI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

521095:APAR RS01855
gene id: 521095:APAR_RS01855
uniprot id: C8W9K1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

521095:APAR RS03750
gene id: 521095:APAR_RS03750
uniprot id: C8WAL9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

521095:APAR RS05940
gene id: 521095:APAR_RS05940
uniprot id: C8W800
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

521095:APAR RS02370
gene id: 521095:APAR_RS02370
uniprot id: C8W9V4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521095:APAR RS02310
gene id: 521095:APAR_RS02310
uniprot id: C8W9U2
names: Similarity
messages: Belongs to the KdgT transporter family.

521095:APAR RS04930
gene id: 521095:APAR_RS04930
uniprot id: C8W7E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521095:APAR RS00410
gene id: 521095:APAR_RS00410
uniprot id: C8W8S3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

521095:APAR RS07015
gene id: 521095:APAR_RS07015
uniprot id: C8W8J7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

521095:APAR RS03170
gene id: 521095:APAR_RS03170
uniprot id: C8WAA6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

521095:APAR RS04925
gene id: 521095:APAR_RS04925
uniprot id: C8W7E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521095:APAR RS03980
gene id: 521095:APAR_RS03980
uniprot id: C8WAR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521095:APAR RS04170
gene id: 521095:APAR_RS04170
uniprot id: C8W701
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

521095:APAR RS06545
gene id: 521095:APAR_RS06545
uniprot id: C8W8B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

521095:APAR RS01140
gene id: 521095:APAR_RS01140
uniprot id: C8W960
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

521095:APAR RS03245
gene id: 521095:APAR_RS03245
uniprot id: C8WAC1
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

521095:APAR RS05870
gene id: 521095:APAR_RS05870
uniprot id: C8W7Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

521095:APAR RS04655
gene id: 521095:APAR_RS04655
uniprot id: C8W798
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

521095:APAR RS03310
gene id: 521095:APAR_RS03310
uniprot id: C8WAD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

521095:APAR RS02470
gene id: 521095:APAR_RS02470
uniprot id: C8W9X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

521095:APAR RS05915
gene id: 521095:APAR_RS05915
uniprot id: C8W7Z5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

521095:APAR RS05980
gene id: 521095:APAR_RS05980
uniprot id: C8W807
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

521095:APAR RS06865
gene id: 521095:APAR_RS06865
uniprot id: C8W8H1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

521095:APAR RS02610
gene id: 521095:APAR_RS02610
uniprot id: C8WA00
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

521095:APAR RS06000
gene id: 521095:APAR_RS06000
uniprot id: C8W811
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

521095:APAR RS04030
gene id: 521095:APAR_RS04030
uniprot id: C8W6X3
names: Similarity
messages: Belongs to the UPF0234 family.

521095:APAR RS06695
gene id: 521095:APAR_RS06695
uniprot id: C8W8D9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

521095:APAR RS04850
gene id: 521095:APAR_RS04850
uniprot id: C8W7D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

521095:APAR RS05810
gene id: 521095:APAR_RS05810
uniprot id: C8W7X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

521095:APAR RS06125
gene id: 521095:APAR_RS06125
uniprot id: C8W831
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

521095:APAR RS06605
gene id: 521095:APAR_RS06605
uniprot id: C8W8C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

521095:APAR RS01470
gene id: 521095:APAR_RS01470
uniprot id: C8W9C6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

521095:APAR RS05375
gene id: 521095:APAR_RS05375
uniprot id: C8W7N5
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

521095:APAR RS03710
gene id: 521095:APAR_RS03710
uniprot id: C8WAL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

521095:APAR RS01360
gene id: 521095:APAR_RS01360
uniprot id: C8W9A3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

521095:APAR RS02570
gene id: 521095:APAR_RS02570
uniprot id: C8W9Z4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

521095:APAR RS05835
gene id: 521095:APAR_RS05835
uniprot id: C8W7X8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521095:APAR RS00715
gene id: 521095:APAR_RS00715
uniprot id: C8W8Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

521095:APAR RS04730
gene id: 521095:APAR_RS04730
uniprot id: C8W7A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

521095:APAR RS02435
gene id: 521095:APAR_RS02435
uniprot id: C8W9W7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

521095:APAR RS05955
gene id: 521095:APAR_RS05955
uniprot id: C8W803
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

521095:APAR RS04065
gene id: 521095:APAR_RS04065
uniprot id: C8W6Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

521095:APAR RS03130
gene id: 521095:APAR_RS03130
uniprot id: C8WAA1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

521095:APAR RS01995
gene id: 521095:APAR_RS01995
uniprot id: C8W9M9
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

521095:APAR RS00205
gene id: 521095:APAR_RS00205
uniprot id: C8W8N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

521095:APAR RS02700
gene id: 521095:APAR_RS02700
uniprot id: C8WA17
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

521095:APAR RS06540
gene id: 521095:APAR_RS06540
uniprot id: C8W8B1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

521095:APAR RS04220
gene id: 521095:APAR_RS04220
uniprot id: C8W711
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

521095:APAR RS03180
gene id: 521095:APAR_RS03180
uniprot id: C8WAA8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

521095:APAR RS04210
gene id: 521095:APAR_RS04210
uniprot id: C8W709
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

521095:APAR RS01265
gene id: 521095:APAR_RS01265
uniprot id: C8W985
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

521095:APAR RS03865
gene id: 521095:APAR_RS03865
uniprot id: C8WAP1
names: Similarity
messages: Belongs to the peptidase S11 family.

521095:APAR RS03455
gene id: 521095:APAR_RS03455
uniprot id: C8WAG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

521095:APAR RS06665
gene id: 521095:APAR_RS06665
uniprot id: C8W7W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

521095:APAR RS04585
gene id: 521095:APAR_RS04585
uniprot id: C8W783
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

521095:APAR RS06600
gene id: 521095:APAR_RS06600
uniprot id: C8W8C3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

521095:APAR RS05505
gene id: 521095:APAR_RS05505
uniprot id: C8W7R1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

521095:APAR RS04780
gene id: 521095:APAR_RS04780
uniprot id: C8W7B8
names: Similarity
messages: Belongs to the DapA family.

521095:APAR RS04910
gene id: 521095:APAR_RS04910
uniprot id: C8W7E4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

521095:APAR RS03635
gene id: 521095:APAR_RS03635
uniprot id: C8WAJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

521095:APAR RS06100
gene id: 521095:APAR_RS06100
uniprot id: C8W826
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

521095:APAR RS01910
gene id: 521095:APAR_RS01910
uniprot id: C8W9L2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS03755
gene id: 521095:APAR_RS03755
uniprot id: C8WAM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

521095:APAR RS05390
gene id: 521095:APAR_RS05390
uniprot id: C8W7N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

521095:APAR RS01830
gene id: 521095:APAR_RS01830
uniprot id: C8W9J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

521095:APAR RS05750
gene id: 521095:APAR_RS05750
uniprot id: C8W7W0
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

521095:APAR RS00350
gene id: 521095:APAR_RS00350
uniprot id: C8W8R2
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS01045
gene id: 521095:APAR_RS01045
uniprot id: C8W942
names: Similarity
messages: Belongs to the HsdR family.

521095:APAR RS02160
gene id: 521095:APAR_RS02160
uniprot id: C8W9R1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

521095:APAR RS01125
gene id: 521095:APAR_RS01125
uniprot id: C8W957
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS06680
gene id: 521095:APAR_RS06680
uniprot id: C8W8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

521095:APAR RS04275
gene id: 521095:APAR_RS04275
uniprot id: C8W721
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

521095:APAR RS05185
gene id: 521095:APAR_RS05185
uniprot id: C8W7J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

521095:APAR RS04430
gene id: 521095:APAR_RS04430
uniprot id: C8W752
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

521095:APAR RS06920
gene id: 521095:APAR_RS06920
uniprot id: C8W8I0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

521095:APAR RS04280
gene id: 521095:APAR_RS04280
uniprot id: C8W722
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

521095:APAR RS04240
gene id: 521095:APAR_RS04240
uniprot id: C8W714
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

521095:APAR RS04690
gene id: 521095:APAR_RS04690
uniprot id: C8W7A4
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS04260
gene id: 521095:APAR_RS04260
uniprot id: C8W718
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

521095:APAR RS03390
gene id: 521095:APAR_RS03390
uniprot id: C8WAF1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

521095:APAR RS04235
gene id: 521095:APAR_RS04235
uniprot id: C8W713
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

521095:APAR RS04520
gene id: 521095:APAR_RS04520
uniprot id: C8W770
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.

521095:APAR RS05105
gene id: 521095:APAR_RS05105
uniprot id: C8W7I2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS00790
gene id: 521095:APAR_RS00790
uniprot id: C8W8Z7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

521095:APAR RS02755
gene id: 521095:APAR_RS02755
uniprot id: C8WA27
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS06900
gene id: 521095:APAR_RS06900
uniprot id: C8W8H7
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS02730
gene id: 521095:APAR_RS02730
uniprot id: C8WA22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

521095:APAR RS00190
gene id: 521095:APAR_RS00190
uniprot id: C8W8N2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

521095:APAR RS00380
gene id: 521095:APAR_RS00380
uniprot id: C8W8R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

521095:APAR RS01980
gene id: 521095:APAR_RS01980
uniprot id: C8W9M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

521095:APAR RS05480
gene id: 521095:APAR_RS05480
uniprot id: C8W7Q6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

521095:APAR RS04250
gene id: 521095:APAR_RS04250
uniprot id: C8W716
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

521095:APAR RS06995
gene id: 521095:APAR_RS06995
uniprot id: C8W8J4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

521095:APAR RS06805
gene id: 521095:APAR_RS06805
uniprot id: C8W8G1
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

521095:APAR RS00105
gene id: 521095:APAR_RS00105
uniprot id: C8W8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

521095:APAR RS04175
gene id: 521095:APAR_RS04175
uniprot id: C8W702
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

521095:APAR RS04360
gene id: 521095:APAR_RS04360
uniprot id: C8W738
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

521095:APAR RS03115
gene id: 521095:APAR_RS03115
uniprot id: C8WA98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

521095:APAR RS00610
gene id: 521095:APAR_RS00610
uniprot id: C8W8W5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

521095:APAR RS04000
gene id: 521095:APAR_RS04000
uniprot id: C8W6W6
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

521095:APAR RS02395
gene id: 521095:APAR_RS02395
uniprot id: C8W9V9
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS04750
gene id: 521095:APAR_RS04750
uniprot id: C8W7B2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

521095:APAR RS01950
gene id: 521095:APAR_RS01950
uniprot id: C8W9M0
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS00765
gene id: 521095:APAR_RS00765
uniprot id: C8W8Z2
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS00250
gene id: 521095:APAR_RS00250
uniprot id: C8W8P3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS03240
gene id: 521095:APAR_RS03240
uniprot id: C8WAC0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

521095:APAR RS02520
gene id: 521095:APAR_RS02520
uniprot id: C8W9Y4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

521095:APAR RS05170
gene id: 521095:APAR_RS05170
uniprot id: C8W7J5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

521095:APAR RS05320
gene id: 521095:APAR_RS05320
uniprot id: C8W7M5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

521095:APAR RS02380
gene id: 521095:APAR_RS02380
uniprot id: C8W9V6
names: Similarity
messages: Belongs to the peptidase M24B family.

521095:APAR RS02075
gene id: 521095:APAR_RS02075
uniprot id: C8W9P5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

521095:APAR RS06265
gene id: 521095:APAR_RS06265
uniprot id: C8W858
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

521095:APAR RS02655
gene id: 521095:APAR_RS02655
uniprot id: C8WA09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

521095:APAR RS00805
gene id: 521095:APAR_RS00805
uniprot id: C8W900
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS06285
gene id: 521095:APAR_RS06285
uniprot id: C8W862
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

521095:APAR RS03380
gene id: 521095:APAR_RS03380
uniprot id: C8WAE9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

521095:APAR RS01100
gene id: 521095:APAR_RS01100
uniprot id: C8W952
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

521095:APAR RS00125
gene id: 521095:APAR_RS00125
uniprot id: C8W8M0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

521095:APAR RS05340
gene id: 521095:APAR_RS05340
uniprot id: C8W7M9
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS02070
gene id: 521095:APAR_RS02070
uniprot id: C8W9P4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

521095:APAR RS06415
gene id: 521095:APAR_RS06415
uniprot id: C8W887
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

521095:APAR RS05515
gene id: 521095:APAR_RS05515
uniprot id: C8W7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

521095:APAR RS01305
gene id: 521095:APAR_RS01305
uniprot id: C8W993
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

521095:APAR RS03445
gene id: 521095:APAR_RS03445
uniprot id: C8WAG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS04895
gene id: 521095:APAR_RS04895
uniprot id: C8W7E1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

521095:APAR RS05900
gene id: 521095:APAR_RS05900
uniprot id: C8W7Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

521095:APAR RS01670
gene id: 521095:APAR_RS01670
uniprot id: C8W9G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

521095:APAR RS04760
gene id: 521095:APAR_RS04760
uniprot id: C8W7B4
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

521095:APAR RS04110
gene id: 521095:APAR_RS04110
uniprot id: C8W6Y9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

521095:APAR RS00720
gene id: 521095:APAR_RS00720
uniprot id: C8W8Y3
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

521095:APAR RS03275
gene id: 521095:APAR_RS03275
uniprot id: C8WAC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

521095:APAR RS03350
gene id: 521095:APAR_RS03350
uniprot id: C8WAE2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

521095:APAR RS03530
gene id: 521095:APAR_RS03530
uniprot id: C8WAH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

521095:APAR RS05865
gene id: 521095:APAR_RS05865
uniprot id: C8W7Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

521095:APAR RS02630
gene id: 521095:APAR_RS02630
uniprot id: C8WA04
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

521095:APAR RS02170
gene id: 521095:APAR_RS02170
uniprot id: C8W9R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS02605
gene id: 521095:APAR_RS02605
uniprot id: C8W9Z9
names: Similarity
messages: Belongs to the peptidase M18 family.

521095:APAR RS04005
gene id: 521095:APAR_RS04005
uniprot id: C8W6W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

521095:APAR RS05490
gene id: 521095:APAR_RS05490
uniprot id: C8W7Q8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

521095:APAR RS05680
gene id: 521095:APAR_RS05680
uniprot id: C8W7U6
names: Similarity
messages: Belongs to the ArsC family.

521095:APAR RS05830
gene id: 521095:APAR_RS05830
uniprot id: C8W7X7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

521095:APAR RS02420
gene id: 521095:APAR_RS02420
uniprot id: C8W9W4
names: Similarity
messages: Belongs to the XseB family.

521095:APAR RS04615
gene id: 521095:APAR_RS04615
uniprot id: C8W790
names: Similarity
messages: Belongs to the peptidase C1 family.

521095:APAR RS03780
gene id: 521095:APAR_RS03780
uniprot id: C8WAM5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS06065
gene id: 521095:APAR_RS06065
uniprot id: C8W819
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

521095:APAR RS02045
gene id: 521095:APAR_RS02045
uniprot id: C8W9N9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

521095:APAR RS04200
gene id: 521095:APAR_RS04200
uniprot id: C8W707
names: Similarity
messages: Belongs to the aldose epimerase family.

521095:APAR RS01850
gene id: 521095:APAR_RS01850
uniprot id: C8W9K0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

521095:APAR RS06640
gene id: 521095:APAR_RS06640
uniprot id: C8W8C8
names: Similarity
messages: Belongs to the DtxR/MntR family.

521095:APAR RS04365
gene id: 521095:APAR_RS04365
uniprot id: C8W739
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

521095:APAR RS03640
gene id: 521095:APAR_RS03640
uniprot id: C8WAK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

521095:APAR RS02925
gene id: 521095:APAR_RS02925
uniprot id: C8WA62
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS06595
gene id: 521095:APAR_RS06595
uniprot id: C8W8C2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

521095:APAR RS01515
gene id: 521095:APAR_RS01515
uniprot id: C8W9D5
names: Subunit
messages: Homodimer.

521095:APAR RS05430
gene id: 521095:APAR_RS05430
uniprot id: C8W7P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

521095:APAR RS04580
gene id: 521095:APAR_RS04580
uniprot id: C8W782
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

521095:APAR RS00130
gene id: 521095:APAR_RS00130
uniprot id: C8W8M1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS03800
gene id: 521095:APAR_RS03800
uniprot id: C8WAM9
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS04165
gene id: 521095:APAR_RS04165
uniprot id: C8W700
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS06825
gene id: 521095:APAR_RS06825
uniprot id: C8W8G5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

521095:APAR RS01200
gene id: 521095:APAR_RS01200
uniprot id: C8W972
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

521095:APAR RS04090
gene id: 521095:APAR_RS04090
uniprot id: C8W6Y5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

521095:APAR RS01250
gene id: 521095:APAR_RS01250
uniprot id: C8W982
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

521095:APAR RS03610
gene id: 521095:APAR_RS03610
uniprot id: C8WAJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

521095:APAR RS03410
gene id: 521095:APAR_RS03410
uniprot id: C8WAF5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

521095:APAR RS01050
gene id: 521095:APAR_RS01050
uniprot id: C8W943
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

521095:APAR RS03155
gene id: 521095:APAR_RS03155
uniprot id: C8WAA4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

521095:APAR RS05385
gene id: 521095:APAR_RS05385
uniprot id: C8W7N7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

521095:APAR RS02385
gene id: 521095:APAR_RS02385
uniprot id: C8W9V7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

521095:APAR RS02775
gene id: 521095:APAR_RS02775
uniprot id: C8WA31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

521095:APAR RS04390
gene id: 521095:APAR_RS04390
uniprot id: C8W744
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

521095:APAR RS04270
gene id: 521095:APAR_RS04270
uniprot id: C8W720
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

521095:APAR RS06700
gene id: 521095:APAR_RS06700
uniprot id: C8W8E0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

521095:APAR RS03080
gene id: 521095:APAR_RS03080
uniprot id: C8WA91
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

521095:APAR RS05890
gene id: 521095:APAR_RS05890
uniprot id: C8W7Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

521095:APAR RS05380
gene id: 521095:APAR_RS05380
uniprot id: C8W7N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

521095:APAR RS04645
gene id: 521095:APAR_RS04645
uniprot id: C8W796
names: Similarity
messages: Belongs to the ELP3 family.

521095:APAR RS04040
gene id: 521095:APAR_RS04040
uniprot id: C8W6X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

521095:APAR RS04010
gene id: 521095:APAR_RS04010
uniprot id: C8W6W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

521095:APAR RS05100
gene id: 521095:APAR_RS05100
uniprot id: C8W7I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

521095:APAR RS04950
gene id: 521095:APAR_RS04950
uniprot id: C8W7F2
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS06550
gene id: 521095:APAR_RS06550
uniprot id: C8W8B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

521095:APAR RS05470
gene id: 521095:APAR_RS05470
uniprot id: C8W7Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

521095:APAR RS04735
gene id: 521095:APAR_RS04735
uniprot id: C8W6W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

521095:APAR RS07040
gene id: 521095:APAR_RS07040
uniprot id: C8W8K2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

521095:APAR RS03435
gene id: 521095:APAR_RS03435
uniprot id: C8WAF9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

521095:APAR RS03600
gene id: 521095:APAR_RS03600
uniprot id: C8WAJ2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

521095:APAR RS02080
gene id: 521095:APAR_RS02080
uniprot id: C8W9P6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

521095:APAR RS03615
gene id: 521095:APAR_RS03615
uniprot id: C8WAJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

521095:APAR RS00750
gene id: 521095:APAR_RS00750
uniprot id: C8W8Y9
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

521095:APAR RS00210
gene id: 521095:APAR_RS00210
uniprot id: C8W8N6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS07030
gene id: 521095:APAR_RS07030
uniprot id: C8W8K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

521095:APAR RS02645
gene id: 521095:APAR_RS02645
uniprot id: C8WA07
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

521095:APAR RS06535
gene id: 521095:APAR_RS06535
uniprot id: C8W8B0
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS05570
gene id: 521095:APAR_RS05570
uniprot id: C8W7S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

521095:APAR RS05895
gene id: 521095:APAR_RS05895
uniprot id: C8W7Z1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

521095:APAR RS00135
gene id: 521095:APAR_RS00135
uniprot id: C8W8M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

521095:APAR RS05720
gene id: 521095:APAR_RS05720
uniprot id: C8W7V4
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

521095:APAR RS01990
gene id: 521095:APAR_RS01990
uniprot id: C8W9M8
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS01505
gene id: 521095:APAR_RS01505
uniprot id: C8W9D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

521095:APAR RS00575
gene id: 521095:APAR_RS00575
uniprot id: C8W8V8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

521095:APAR RS05615
gene id: 521095:APAR_RS05615
uniprot id: C8W7T3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

521095:APAR RS02325
gene id: 521095:APAR_RS02325
uniprot id: C8W9U5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

521095:APAR RS02695
gene id: 521095:APAR_RS02695
uniprot id: C8WA16
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

521095:APAR RS00100
gene id: 521095:APAR_RS00100
uniprot id: C8W8L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

521095:APAR RS05920
gene id: 521095:APAR_RS05920
uniprot id: C8W7Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

521095:APAR RS03085
gene id: 521095:APAR_RS03085
uniprot id: C8WA92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

521095:APAR RS06405
gene id: 521095:APAR_RS06405
uniprot id: C8W885
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

521095:APAR RS03555
gene id: 521095:APAR_RS03555
uniprot id: C8WAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

521095:APAR RS00455
gene id: 521095:APAR_RS00455
uniprot id: C8W8T3
names: Similarity
messages: Belongs to the Dps family.

521095:APAR RS05605
gene id: 521095:APAR_RS05605
uniprot id: C8W7T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

521095:APAR RS03320
gene id: 521095:APAR_RS03320
uniprot id: C8WAD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

521095:APAR RS01915
gene id: 521095:APAR_RS01915
uniprot id: C8W9L3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

521095:APAR RS01455
gene id: 521095:APAR_RS01455
uniprot id: C8W9C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

521095:APAR RS05580
gene id: 521095:APAR_RS05580
uniprot id: C8W7S6
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

521095:APAR RS02020
gene id: 521095:APAR_RS02020
uniprot id: C8W9N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

521095:APAR RS01905
gene id: 521095:APAR_RS01905
uniprot id: C8W9L1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

521095:APAR RS06390
gene id: 521095:APAR_RS06390
uniprot id: C8W882
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

521095:APAR RS06250
gene id: 521095:APAR_RS06250
uniprot id: C8W855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Cytoplasm

521095:APAR RS05485
gene id: 521095:APAR_RS05485
uniprot id: C8W7Q7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

521095:APAR RS06005
gene id: 521095:APAR_RS06005
uniprot id: C8W812
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

521095:APAR RS06205
gene id: 521095:APAR_RS06205
uniprot id: C8W847
names: Similarity
messages: Belongs to the UPF0102 family.

521095:APAR RS06150
gene id: 521095:APAR_RS06150
uniprot id: C8W836
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS04425
gene id: 521095:APAR_RS04425
uniprot id: C8W751
names: Similarity
messages: Belongs to the asp23 family.

521095:APAR RS00885
gene id: 521095:APAR_RS00885
uniprot id: C8W915
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

521095:APAR RS05820
gene id: 521095:APAR_RS05820
uniprot id: C8W7X5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

521095:APAR RS03255
gene id: 521095:APAR_RS03255
uniprot id: C8WAC3
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

521095:APAR RS05875
gene id: 521095:APAR_RS05875
uniprot id: C8W7Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

521095:APAR RS06765
gene id: 521095:APAR_RS06765
uniprot id: C8W8F3
names: Similarity
messages: Belongs to the thioredoxin family.

521095:APAR RS04075
gene id: 521095:APAR_RS04075
uniprot id: C8W6Y2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

521095:APAR RS06675
gene id: 521095:APAR_RS06675
uniprot id: C8W8D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

521095:APAR RS03875
gene id: 521095:APAR_RS03875
uniprot id: C8WAP3
names: Similarity
messages: Belongs to the RutC family.

521095:APAR RS00745
gene id: 521095:APAR_RS00745
uniprot id: C8W8Y8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

521095:APAR RS01345
gene id: 521095:APAR_RS01345
uniprot id: C8W9A0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

521095:APAR RS05460
gene id: 521095:APAR_RS05460
uniprot id: C8W7Q2
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS03670
gene id: 521095:APAR_RS03670
uniprot id: C8WAK6
names: Subcellular Location Annotation
messages: Membrane

521095:APAR RS06155
gene id: 521095:APAR_RS06155
uniprot id: C8W837
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

521095:APAR RS06445
gene id: 521095:APAR_RS06445
uniprot id: C8W893
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.