519472:BHY08 RS06265
gene id: 519472:BHY08_RS06265
uniprot id: A0A1J0A6B3
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

519472:BHY08 RS03620
gene id: 519472:BHY08_RS03620
uniprot id: A0A1J0A504
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

519472:BHY08 RS04700
gene id: 519472:BHY08_RS04700
uniprot id: A0A1J0A5H5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

519472:BHY08 RS03670
gene id: 519472:BHY08_RS03670
uniprot id: A0A1J0A531
names: Similarity
messages: Belongs to the EamA transporter family.

519472:BHY08 RS02205
gene id: 519472:BHY08_RS02205
uniprot id: A0A1J0A492
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

519472:BHY08 RS05655
gene id: 519472:BHY08_RS05655
uniprot id: A0A1J0A5Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

519472:BHY08 RS05135
gene id: 519472:BHY08_RS05135
uniprot id: A0A1J0A5R1
names: Similarity
messages: Belongs to the peptidase C59 family.

519472:BHY08 RS00965
gene id: 519472:BHY08_RS00965
uniprot id: A0A1J0A3L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

519472:BHY08 RS10530
gene id: 519472:BHY08_RS10530
uniprot id: A0A1J0A8A5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS01385
gene id: 519472:BHY08_RS01385
uniprot id: A0A1J0A3U3
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

519472:BHY08 RS07475
gene id: 519472:BHY08_RS07475
uniprot id: A0A1J0A6Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

519472:BHY08 RS03895
gene id: 519472:BHY08_RS03895
uniprot id: A0A1J0A533
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

519472:BHY08 RS03890
gene id: 519472:BHY08_RS03890
uniprot id: A0A1J0A8G9
names: Similarity
messages: Belongs to the peptidase C1 family.

519472:BHY08 RS07180
gene id: 519472:BHY08_RS07180
uniprot id: A0A1J0A6S6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

519472:BHY08 RS03845
gene id: 519472:BHY08_RS03845
uniprot id: A0A1J0A523
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

519472:BHY08 RS04010
gene id: 519472:BHY08_RS04010
uniprot id: A0A1J0A548
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519472:BHY08 RS03495
gene id: 519472:BHY08_RS03495
uniprot id: A0A1J0A501
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS02320
gene id: 519472:BHY08_RS02320
uniprot id: A0A1J0A493
names: Similarity
messages: Belongs to the UPF0173 family.

519472:BHY08 RS10260
gene id: 519472:BHY08_RS10260
uniprot id: A0A1J0A888
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

519472:BHY08 RS04375
gene id: 519472:BHY08_RS04375
uniprot id: A0A1J0A5B9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

519472:BHY08 RS05315
gene id: 519472:BHY08_RS05315
uniprot id: A0A1J0A5U2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS07980
gene id: 519472:BHY08_RS07980
uniprot id: A0A1J0A745
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS07520
gene id: 519472:BHY08_RS07520
uniprot id: A0A1J0A6Z8
names: Similarity
messages: Belongs to the FGGY kinase family.

519472:BHY08 RS06090
gene id: 519472:BHY08_RS06090
uniprot id: A0A1J0A682
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

519472:BHY08 RS07910
gene id: 519472:BHY08_RS07910
uniprot id: A0A1J0A763
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

519472:BHY08 RS09955
gene id: 519472:BHY08_RS09955
uniprot id: A0A1J0A833
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

519472:BHY08 RS03525
gene id: 519472:BHY08_RS03525
uniprot id: A0A1J0A4W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

519472:BHY08 RS05930
gene id: 519472:BHY08_RS05930
uniprot id: A0A1J0A644
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS08565
gene id: 519472:BHY08_RS08565
uniprot id: A0A1J0A7I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS02005
gene id: 519472:BHY08_RS02005
uniprot id: A0A1J0A446
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS06270
gene id: 519472:BHY08_RS06270
uniprot id: A0A1J0A6A4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS04130
gene id: 519472:BHY08_RS04130
uniprot id: A0A1J0A571
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

519472:BHY08 RS00890
gene id: 519472:BHY08_RS00890
uniprot id: A0A1J0A3L7
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

519472:BHY08 RS07550
gene id: 519472:BHY08_RS07550
uniprot id: A0A1J0A6Y7
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

519472:BHY08 RS01325
gene id: 519472:BHY08_RS01325
uniprot id: A0A1J0A3U8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).

519472:BHY08 RS08770
gene id: 519472:BHY08_RS08770
uniprot id: A0A1J0A7J0
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

519472:BHY08 RS09090
gene id: 519472:BHY08_RS09090
uniprot id: A0A1J0A7N3
names: Similarity
messages: Belongs to the GSP E family.

519472:BHY08 RS00160
gene id: 519472:BHY08_RS00160
uniprot id: A0A1J0A387
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS03960
gene id: 519472:BHY08_RS03960
uniprot id: A0A1J0A575
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS03935
gene id: 519472:BHY08_RS03935
uniprot id: A0A1J0A536
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS07605
gene id: 519472:BHY08_RS07605
uniprot id: A0A1J0A700
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

519472:BHY08 RS05070
gene id: 519472:BHY08_RS05070
uniprot id: A0A1J0A5P1
names: Similarity
messages: Belongs to the PemK/MazF family.

519472:BHY08 RS09715
gene id: 519472:BHY08_RS09715
uniprot id: A0A1J0A806
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

519472:BHY08 RS04830
gene id: 519472:BHY08_RS04830
uniprot id: A0A1J0A5J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

519472:BHY08 RS05005
gene id: 519472:BHY08_RS05005
uniprot id: A0A1J0A5N6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

519472:BHY08 RS00770
gene id: 519472:BHY08_RS00770
uniprot id: A0A1J0A3I1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

519472:BHY08 RS07775
gene id: 519472:BHY08_RS07775
uniprot id: A0A1J0A749
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

519472:BHY08 RS06180
gene id: 519472:BHY08_RS06180
uniprot id: A0A1J0A684
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

519472:BHY08 RS08610
gene id: 519472:BHY08_RS08610
uniprot id: A0A1J0A7F6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

519472:BHY08 RS06490
gene id: 519472:BHY08_RS06490
uniprot id: A0A1J0A6E1
names: Similarity
messages: Belongs to the asparaginase 1 family.

519472:BHY08 RS00205
gene id: 519472:BHY08_RS00205
uniprot id: A0A1J0A397
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

519472:BHY08 RS02215
gene id: 519472:BHY08_RS02215
uniprot id: A0A1J0A475
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS03105
gene id: 519472:BHY08_RS03105
uniprot id: A0A1J0A4S0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

519472:BHY08 RS01905
gene id: 519472:BHY08_RS01905
uniprot id: A0A1J0A421
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS03560
gene id: 519472:BHY08_RS03560
uniprot id: A0A1J0A8G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

519472:BHY08 RS05155
gene id: 519472:BHY08_RS05155
uniprot id: A0A1J0A5Q2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS05500
gene id: 519472:BHY08_RS05500
uniprot id: A0A1J0A5Y9
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07100
gene id: 519472:BHY08_RS07100
uniprot id: A0A1J0A6Q0
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07070
gene id: 519472:BHY08_RS07070
uniprot id: A0A1J0A6P7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

519472:BHY08 RS04645
gene id: 519472:BHY08_RS04645
uniprot id: A0A1J0A5G4
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

519472:BHY08 RS10145
gene id: 519472:BHY08_RS10145
uniprot id: A0A1J0A887
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

519472:BHY08 RS09210
gene id: 519472:BHY08_RS09210
uniprot id: A0A1J0A7S5
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS04555
gene id: 519472:BHY08_RS04555
uniprot id: A0A1J0A5F6
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

519472:BHY08 RS00095
gene id: 519472:BHY08_RS00095
uniprot id: A0A1J0A392
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

519472:BHY08 RS08335
gene id: 519472:BHY08_RS08335
uniprot id: A0A1J0A7D3
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS05565
gene id: 519472:BHY08_RS05565
uniprot id: A0A1J0A5X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

519472:BHY08 RS01995
gene id: 519472:BHY08_RS01995
uniprot id: A0A1J0A476
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS06250
gene id: 519472:BHY08_RS06250
uniprot id: A0A1J0A6D1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

519472:BHY08 RS03600
gene id: 519472:BHY08_RS03600
uniprot id: A0A1J0A4W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

519472:BHY08 RS00430
gene id: 519472:BHY08_RS00430
uniprot id: A0A1J0A3D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

519472:BHY08 RS00725
gene id: 519472:BHY08_RS00725
uniprot id: A0A1J0A3G0
names: Similarity
messages: Belongs to the YicC/YloC family.

519472:BHY08 RS08425
gene id: 519472:BHY08_RS08425
uniprot id: A0A1J0A7C1
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07170
gene id: 519472:BHY08_RS07170
uniprot id: A0A1J0A6T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

519472:BHY08 RS09245
gene id: 519472:BHY08_RS09245
uniprot id: A0A1J0A7R2
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07290
gene id: 519472:BHY08_RS07290
uniprot id: A0A1J0A6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS00775
gene id: 519472:BHY08_RS00775
uniprot id: A0A1J0A3I0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

519472:BHY08 RS09325
gene id: 519472:BHY08_RS09325
uniprot id: A0A1J0A7T0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

519472:BHY08 RS10115
gene id: 519472:BHY08_RS10115
uniprot id: A0A1J0A879
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

519472:BHY08 RS11165
gene id: 519472:BHY08_RS11165
uniprot id: A0A1J0A709
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

519472:BHY08 RS02700
gene id: 519472:BHY08_RS02700
uniprot id: A0A1J0A4J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS09240
gene id: 519472:BHY08_RS09240
uniprot id: A0A1J0A7U4
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS00945
gene id: 519472:BHY08_RS00945
uniprot id: A0A1J0A3L6
names: Subcellular Location Annotation
messages: Cytoplasm

519472:BHY08 RS09655
gene id: 519472:BHY08_RS09655
uniprot id: A0A1J0A802
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

519472:BHY08 RS08550
gene id: 519472:BHY08_RS08550
uniprot id: A0A1J0A7E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS07945
gene id: 519472:BHY08_RS07945
uniprot id: A0A1J0A743
names: Similarity
messages: Belongs to the OsmC/Ohr family.

519472:BHY08 RS02780
gene id: 519472:BHY08_RS02780
uniprot id: A0A1J0A4K2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

519472:BHY08 RS10615
gene id: 519472:BHY08_RS10615
uniprot id: A0A1J0A8N9
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

519472:BHY08 RS02670
gene id: 519472:BHY08_RS02670
uniprot id: A0A1J0A4I4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

519472:BHY08 RS10070
gene id: 519472:BHY08_RS10070
uniprot id: A0A1J0A870
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

519472:BHY08 RS07565
gene id: 519472:BHY08_RS07565
uniprot id: A0A1J0A6Z2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

519472:BHY08 RS03580
gene id: 519472:BHY08_RS03580
uniprot id: A0A1J0A517
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

519472:BHY08 RS06085
gene id: 519472:BHY08_RS06085
uniprot id: A0A1J0A672
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

519472:BHY08 RS10015
gene id: 519472:BHY08_RS10015
uniprot id: A0A1J0A865
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

519472:BHY08 RS04785
gene id: 519472:BHY08_RS04785
uniprot id: A0A1J0A5J3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS07600
gene id: 519472:BHY08_RS07600
uniprot id: A0A1J0A712
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

519472:BHY08 RS08350
gene id: 519472:BHY08_RS08350
uniprot id: A0A1J0A7D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

519472:BHY08 RS02475
gene id: 519472:BHY08_RS02475
uniprot id: A0A1J0A4B6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

519472:BHY08 RS02575
gene id: 519472:BHY08_RS02575
uniprot id: A0A1J0A4G4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

519472:BHY08 RS02280
gene id: 519472:BHY08_RS02280
uniprot id: A0A1J0A4A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS10200
gene id: 519472:BHY08_RS10200
uniprot id: A0A1J0A890
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

519472:BHY08 RS06485
gene id: 519472:BHY08_RS06485
uniprot id: A0A1J0A6H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

519472:BHY08 RS10255
gene id: 519472:BHY08_RS10255
uniprot id: A0A1J0A8A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

519472:BHY08 RS06230
gene id: 519472:BHY08_RS06230
uniprot id: A0A1J0A693
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

519472:BHY08 RS03125
gene id: 519472:BHY08_RS03125
uniprot id: A0A1J0A4R1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

519472:BHY08 RS06590
gene id: 519472:BHY08_RS06590
uniprot id: A0A1J0A6F7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

519472:BHY08 RS05985
gene id: 519472:BHY08_RS05985
uniprot id: A0A1J0A657
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519472:BHY08 RS05540
gene id: 519472:BHY08_RS05540
uniprot id: A0A1J0A600
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

519472:BHY08 RS05735
gene id: 519472:BHY08_RS05735
uniprot id: A0A1J0A608
names: Similarity
messages: Belongs to the UPF0145 family.

519472:BHY08 RS09730
gene id: 519472:BHY08_RS09730
uniprot id: A0A1J0A830
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

519472:BHY08 RS00660
gene id: 519472:BHY08_RS00660
uniprot id: A0A1J0A3F8
names: Similarity
messages: Belongs to the UPF0342 family.

519472:BHY08 RS10120
gene id: 519472:BHY08_RS10120
uniprot id: A0A1J0A894
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

519472:BHY08 RS04250
gene id: 519472:BHY08_RS04250
uniprot id: A0A1J0A590
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

519472:BHY08 RS10080
gene id: 519472:BHY08_RS10080
uniprot id: A0A1J0A861
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS04365
gene id: 519472:BHY08_RS04365
uniprot id: A0A1J0A5C1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

519472:BHY08 RS08360
gene id: 519472:BHY08_RS08360
uniprot id: A0A1J0A7C4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

519472:BHY08 RS08495
gene id: 519472:BHY08_RS08495
uniprot id: A0A1J0A7E7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS06930
gene id: 519472:BHY08_RS06930
uniprot id: A0A1J0A6M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS04925
gene id: 519472:BHY08_RS04925
uniprot id: A0A1J0A5L8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Homohexamer.

519472:BHY08 RS00805
gene id: 519472:BHY08_RS00805
uniprot id: A0A1J0A3J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

519472:BHY08 RS06000
gene id: 519472:BHY08_RS06000
uniprot id: A0A1J0A663
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS05780
gene id: 519472:BHY08_RS05780
uniprot id: A0A1J0A614
names: Similarity
messages: Belongs to the peptidase C59 family.

519472:BHY08 RS04220
gene id: 519472:BHY08_RS04220
uniprot id: A0A1J0A594
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

519472:BHY08 RS10525
gene id: 519472:BHY08_RS10525
uniprot id: A0A1J0A8B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

519472:BHY08 RS09105
gene id: 519472:BHY08_RS09105
uniprot id: A0A1J0A7S6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

519472:BHY08 RS04435
gene id: 519472:BHY08_RS04435
uniprot id: A0A1J0A5C4
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS05240
gene id: 519472:BHY08_RS05240
uniprot id: A0A1J0A5U0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

519472:BHY08 RS01135
gene id: 519472:BHY08_RS01135
uniprot id: A0A1J0A3Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

519472:BHY08 RS09265
gene id: 519472:BHY08_RS09265
uniprot id: A0A1J0A7R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS06925
gene id: 519472:BHY08_RS06925
uniprot id: A0A1J0A6P3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

519472:BHY08 RS05510
gene id: 519472:BHY08_RS05510
uniprot id: A0A1J0A5X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS00210
gene id: 519472:BHY08_RS00210
uniprot id: A0A1J0A398
names: Subcellular Location Annotation
messages: Cytoplasm

519472:BHY08 RS01285
gene id: 519472:BHY08_RS01285
uniprot id: A0A1J0A3U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

519472:BHY08 RS08185
gene id: 519472:BHY08_RS08185
uniprot id: A0A1J0A780
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS02865
gene id: 519472:BHY08_RS02865
uniprot id: A0A1J0A4L4
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

519472:BHY08 RS01645
gene id: 519472:BHY08_RS01645
uniprot id: A0A1J0A3X3
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS02720
gene id: 519472:BHY08_RS02720
uniprot id: A0A1J0A4H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

519472:BHY08 RS05940
gene id: 519472:BHY08_RS05940
uniprot id: A0A1J0A673
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

519472:BHY08 RS08840
gene id: 519472:BHY08_RS08840
uniprot id: A0A1J0A7M8
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

519472:BHY08 RS10515
gene id: 519472:BHY08_RS10515
uniprot id: A0A1J0A8D1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

519472:BHY08 RS06260
gene id: 519472:BHY08_RS06260
uniprot id: A0A1J0A6A0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519472:BHY08 RS05955
gene id: 519472:BHY08_RS05955
uniprot id: A0A1J0A646
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

519472:BHY08 RS01465
gene id: 519472:BHY08_RS01465
uniprot id: A0A1J0A3U6
names: Similarity
messages: Belongs to the UPF0758 family.

519472:BHY08 RS04930
gene id: 519472:BHY08_RS04930
uniprot id: A0A1J0A5L5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

519472:BHY08 RS09425
gene id: 519472:BHY08_RS09425
uniprot id: A0A1J0A7X7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

519472:BHY08 RS06320
gene id: 519472:BHY08_RS06320
uniprot id: A0A1J0A6B6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS04170
gene id: 519472:BHY08_RS04170
uniprot id: A0A1J0A579
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

519472:BHY08 RS07555
gene id: 519472:BHY08_RS07555
uniprot id: A0A1J0A704
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07300
gene id: 519472:BHY08_RS07300
uniprot id: A0A1J0A6V8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

519472:BHY08 RS00170
gene id: 519472:BHY08_RS00170
uniprot id: A0A1J0A389
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

519472:BHY08 RS01685
gene id: 519472:BHY08_RS01685
uniprot id: A0A1J0A3Z8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

519472:BHY08 RS07135
gene id: 519472:BHY08_RS07135
uniprot id: A0A1J0A6Q6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

519472:BHY08 RS00790
gene id: 519472:BHY08_RS00790
uniprot id: A0A1J0A3I9
names: Similarity
messages: Belongs to the asp23 family.

519472:BHY08 RS03130
gene id: 519472:BHY08_RS03130
uniprot id: A0A1J0A4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

519472:BHY08 RS10075
gene id: 519472:BHY08_RS10075
uniprot id: A0A1J0A884
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

519472:BHY08 RS05425
gene id: 519472:BHY08_RS05425
uniprot id: A0A1J0A5V9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

519472:BHY08 RS00630
gene id: 519472:BHY08_RS00630
uniprot id: A0A1J0A3G4
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

519472:BHY08 RS10110
gene id: 519472:BHY08_RS10110
uniprot id: A0A1J0A885
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

519472:BHY08 RS00440
gene id: 519472:BHY08_RS00440
uniprot id: A0A1J0A3E3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

519472:BHY08 RS06785
gene id: 519472:BHY08_RS06785
uniprot id: A0A1J0A6L9
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

519472:BHY08 RS09340
gene id: 519472:BHY08_RS09340
uniprot id: A0A1J0A7S7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

519472:BHY08 RS03455
gene id: 519472:BHY08_RS03455
uniprot id: A0A1J0A4V9
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

519472:BHY08 RS07925
gene id: 519472:BHY08_RS07925
uniprot id: A0A1J0A752
names: Similarity
messages: Belongs to the peptidase M29 family.

519472:BHY08 RS05340
gene id: 519472:BHY08_RS05340
uniprot id: A0A1J0A5U4
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS04310
gene id: 519472:BHY08_RS04310
uniprot id: A0A1J0A5C9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

519472:BHY08 RS06510
gene id: 519472:BHY08_RS06510
uniprot id: A0A1J0A6E8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

519472:BHY08 RS10150
gene id: 519472:BHY08_RS10150
uniprot id: A0A1J0A869
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

519472:BHY08 RS09910
gene id: 519472:BHY08_RS09910
uniprot id: A0A1J0A856
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS08870
gene id: 519472:BHY08_RS08870
uniprot id: A0A1J0A7J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

519472:BHY08 RS09585
gene id: 519472:BHY08_RS09585
uniprot id: A0A1J0A7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

519472:BHY08 RS00070
gene id: 519472:BHY08_RS00070
uniprot id: A0A1J0A382
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

519472:BHY08 RS03540
gene id: 519472:BHY08_RS03540
uniprot id: A0A1J0A4X9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

519472:BHY08 RS03490
gene id: 519472:BHY08_RS03490
uniprot id: A0A1J0A4Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

519472:BHY08 RS08925
gene id: 519472:BHY08_RS08925
uniprot id: A0A1J0A7L5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

519472:BHY08 RS07630
gene id: 519472:BHY08_RS07630
uniprot id: A0A1J0A725
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

519472:BHY08 RS01025
gene id: 519472:BHY08_RS01025
uniprot id: A0A1J0A3N8
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

519472:BHY08 RS02070
gene id: 519472:BHY08_RS02070
uniprot id: A0A1J0A453
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

519472:BHY08 RS07490
gene id: 519472:BHY08_RS07490
uniprot id: A0A1J0A6X7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

519472:BHY08 RS09205
gene id: 519472:BHY08_RS09205
uniprot id: A0A1J0A7U2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

519472:BHY08 RS02695
gene id: 519472:BHY08_RS02695
uniprot id: A0A1J0A4I0
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS10240
gene id: 519472:BHY08_RS10240
uniprot id: A0A1J0A886
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

519472:BHY08 RS06520
gene id: 519472:BHY08_RS06520
uniprot id: A0A1J0A6F1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

519472:BHY08 RS09435
gene id: 519472:BHY08_RS09435
uniprot id: A0A1J0A8M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

519472:BHY08 RS06955
gene id: 519472:BHY08_RS06955
uniprot id: A0A1J0A6M4
names: Similarity
messages: Belongs to the TelA family.

519472:BHY08 RS06225
gene id: 519472:BHY08_RS06225
uniprot id: A0A1J0A6A5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

519472:BHY08 RS01035
gene id: 519472:BHY08_RS01035
uniprot id: A0A1J0A3M1
names: Function
names: Similarity
names: Subunit
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.

519472:BHY08 RS01050
gene id: 519472:BHY08_RS01050
uniprot id: A0A1J0A3N1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

519472:BHY08 RS10085
gene id: 519472:BHY08_RS10085
uniprot id: A0A1J0A891
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

519472:BHY08 RS08915
gene id: 519472:BHY08_RS08915
uniprot id: A0A1J0A7N8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

519472:BHY08 RS01330
gene id: 519472:BHY08_RS01330
uniprot id: A0A1J0A3S8
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

519472:BHY08 RS05705
gene id: 519472:BHY08_RS05705
uniprot id: A0A1J0A604
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

519472:BHY08 RS06140
gene id: 519472:BHY08_RS06140
uniprot id: A0A1J0A689
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

519472:BHY08 RS00705
gene id: 519472:BHY08_RS00705
uniprot id: A0A1J0A3G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

519472:BHY08 RS06645
gene id: 519472:BHY08_RS06645
uniprot id: A0A1J0A6H9
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

519472:BHY08 RS07095
gene id: 519472:BHY08_RS07095
uniprot id: A0A1J0A6P5
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

519472:BHY08 RS00050
gene id: 519472:BHY08_RS00050
uniprot id: A0A1J0A368
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

519472:BHY08 RS05445
gene id: 519472:BHY08_RS05445
uniprot id: A0A1J0A5Y2
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS01910
gene id: 519472:BHY08_RS01910
uniprot id: A0A1J0A449
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

519472:BHY08 RS07200
gene id: 519472:BHY08_RS07200
uniprot id: A0A1J0A6U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS07365
gene id: 519472:BHY08_RS07365
uniprot id: A0A1J0A6V6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

519472:BHY08 RS04235
gene id: 519472:BHY08_RS04235
uniprot id: A0A1J0A595
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

519472:BHY08 RS08085
gene id: 519472:BHY08_RS08085
uniprot id: A0A1J0A767
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

519472:BHY08 RS04255
gene id: 519472:BHY08_RS04255
uniprot id: A0A1J0A593
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

519472:BHY08 RS00700
gene id: 519472:BHY08_RS00700
uniprot id: A0A1J0A3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

519472:BHY08 RS01070
gene id: 519472:BHY08_RS01070
uniprot id: A0A1J0A3N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

519472:BHY08 RS03335
gene id: 519472:BHY08_RS03335
uniprot id: A0A1J0A4S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

519472:BHY08 RS03020
gene id: 519472:BHY08_RS03020
uniprot id: A0A1J0A4M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS08220
gene id: 519472:BHY08_RS08220
uniprot id: A0A1J0A7A5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

519472:BHY08 RS04715
gene id: 519472:BHY08_RS04715
uniprot id: A0A1J0A5J8
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

519472:BHY08 RS03595
gene id: 519472:BHY08_RS03595
uniprot id: A0A1J0A4X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

519472:BHY08 RS02620
gene id: 519472:BHY08_RS02620
uniprot id: A0A1J0A4F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

519472:BHY08 RS06990
gene id: 519472:BHY08_RS06990
uniprot id: A0A1J0A8H7
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS00690
gene id: 519472:BHY08_RS00690
uniprot id: A0A1J0A3G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

519472:BHY08 RS07940
gene id: 519472:BHY08_RS07940
uniprot id: A0A1J0A773
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

519472:BHY08 RS05380
gene id: 519472:BHY08_RS05380
uniprot id: A0A1J0A5V1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

519472:BHY08 RS07415
gene id: 519472:BHY08_RS07415
uniprot id: A0A1J0A6V2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

519472:BHY08 RS07730
gene id: 519472:BHY08_RS07730
uniprot id: A0A1J0A711
names: Similarity
messages: Belongs to the UPF0374 family.

519472:BHY08 RS02990
gene id: 519472:BHY08_RS02990
uniprot id: A0A1J0A4N7
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07210
gene id: 519472:BHY08_RS07210
uniprot id: A0A1J0A6U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS07470
gene id: 519472:BHY08_RS07470
uniprot id: A0A1J0A6X0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

519472:BHY08 RS04400
gene id: 519472:BHY08_RS04400
uniprot id: A0A1J0A8E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

519472:BHY08 RS02640
gene id: 519472:BHY08_RS02640
uniprot id: A0A1J0A4F8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS00990
gene id: 519472:BHY08_RS00990
uniprot id: A0A1J0A3L4
names: Similarity
messages: Belongs to the aldolase LacD family.

519472:BHY08 RS04135
gene id: 519472:BHY08_RS04135
uniprot id: A0A1J0A5A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

519472:BHY08 RS04845
gene id: 519472:BHY08_RS04845
uniprot id: A0A1J0A5K1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

519472:BHY08 RS06860
gene id: 519472:BHY08_RS06860
uniprot id: A0A1J0A6K8
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07185
gene id: 519472:BHY08_RS07185
uniprot id: A0A1J0A6R2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

519472:BHY08 RS02760
gene id: 519472:BHY08_RS02760
uniprot id: A0A1J0A4L9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

519472:BHY08 RS06940
gene id: 519472:BHY08_RS06940
uniprot id: A0A1J0A6P9
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

519472:BHY08 RS07545
gene id: 519472:BHY08_RS07545
uniprot id: A0A1J0A703
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

519472:BHY08 RS04840
gene id: 519472:BHY08_RS04840
uniprot id: A0A1J0A5K2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

519472:BHY08 RS01190
gene id: 519472:BHY08_RS01190
uniprot id: A0A1J0A3R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

519472:BHY08 RS01935
gene id: 519472:BHY08_RS01935
uniprot id: A0A1J0A439
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

519472:BHY08 RS03725
gene id: 519472:BHY08_RS03725
uniprot id: A0A1J0A502
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS08230
gene id: 519472:BHY08_RS08230
uniprot id: A0A1J0A787
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

519472:BHY08 RS07780
gene id: 519472:BHY08_RS07780
uniprot id: A0A1J0A722
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

519472:BHY08 RS07035
gene id: 519472:BHY08_RS07035
uniprot id: A0A1J0A6R4
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS01115
gene id: 519472:BHY08_RS01115
uniprot id: A0A1J0A3P4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

519472:BHY08 RS04200
gene id: 519472:BHY08_RS04200
uniprot id: A0A1J0A589
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

519472:BHY08 RS09565
gene id: 519472:BHY08_RS09565
uniprot id: A0A1J0A800
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS00305
gene id: 519472:BHY08_RS00305
uniprot id: A0A1J0A3C1
names: Similarity
messages: Belongs to the peptidase M20A family.

519472:BHY08 RS07165
gene id: 519472:BHY08_RS07165
uniprot id: A0A1J0A6T5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS02570
gene id: 519472:BHY08_RS02570
uniprot id: A0A1J0A4E3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

519472:BHY08 RS04670
gene id: 519472:BHY08_RS04670
uniprot id: A0A1J0A5I1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

519472:BHY08 RS00390
gene id: 519472:BHY08_RS00390
uniprot id: A0A1J0A3D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

519472:BHY08 RS03040
gene id: 519472:BHY08_RS03040
uniprot id: A0A1J0A4P2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

519472:BHY08 RS07335
gene id: 519472:BHY08_RS07335
uniprot id: A0A1J0A6T8
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS09015
gene id: 519472:BHY08_RS09015
uniprot id: A0A1J0A7N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

519472:BHY08 RS02110
gene id: 519472:BHY08_RS02110
uniprot id: A0A1J0A487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS03640
gene id: 519472:BHY08_RS03640
uniprot id: A0A1J0A4X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

519472:BHY08 RS00750
gene id: 519472:BHY08_RS00750
uniprot id: A0A1J0A3I2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

519472:BHY08 RS07485
gene id: 519472:BHY08_RS07485
uniprot id: A0A1J0A6X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

519472:BHY08 RS08280
gene id: 519472:BHY08_RS08280
uniprot id: A0A1J0A795
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

519472:BHY08 RS09095
gene id: 519472:BHY08_RS09095
uniprot id: A0A1J0A7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

519472:BHY08 RS09250
gene id: 519472:BHY08_RS09250
uniprot id: A0A1J0A7V0
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

519472:BHY08 RS05345
gene id: 519472:BHY08_RS05345
uniprot id: A0A1J0A5T4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

519472:BHY08 RS07715
gene id: 519472:BHY08_RS07715
uniprot id: A0A1J0A724
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

519472:BHY08 RS08605
gene id: 519472:BHY08_RS08605
uniprot id: A0A1J0A7I7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

519472:BHY08 RS00175
gene id: 519472:BHY08_RS00175
uniprot id: A0A1J0A391
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

519472:BHY08 RS02170
gene id: 519472:BHY08_RS02170
uniprot id: A0A1J0A467
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

519472:BHY08 RS02655
gene id: 519472:BHY08_RS02655
uniprot id: A0A1J0A4H1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

519472:BHY08 RS07395
gene id: 519472:BHY08_RS07395
uniprot id: A0A1J0A6X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS01945
gene id: 519472:BHY08_RS01945
uniprot id: A0A1J0A432
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

519472:BHY08 RS07840
gene id: 519472:BHY08_RS07840
uniprot id: A0A1J0A755
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

519472:BHY08 RS00735
gene id: 519472:BHY08_RS00735
uniprot id: A0A1J0A3G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

519472:BHY08 RS07975
gene id: 519472:BHY08_RS07975
uniprot id: A0A1J0A760
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

519472:BHY08 RS06690
gene id: 519472:BHY08_RS06690
uniprot id: A0A1J0A6H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

519472:BHY08 RS10985
gene id: 519472:BHY08_RS10985
uniprot id: A0A1J0A8K6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519472:BHY08 RS06190
gene id: 519472:BHY08_RS06190
uniprot id: A0A1J0A688
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

519472:BHY08 RS03425
gene id: 519472:BHY08_RS03425
uniprot id: A0A1J0A4T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0298 family.
messages: Cytoplasm

519472:BHY08 RS04455
gene id: 519472:BHY08_RS04455
uniprot id: A0A1J0A5F3
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS05935
gene id: 519472:BHY08_RS05935
uniprot id: A0A1J0A670
names: Function
names: Similarity
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

519472:BHY08 RS06080
gene id: 519472:BHY08_RS06080
uniprot id: A0A1J0A696
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

519472:BHY08 RS03675
gene id: 519472:BHY08_RS03675
uniprot id: A0A1J0A507
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

519472:BHY08 RS07845
gene id: 519472:BHY08_RS07845
uniprot id: A0A1J0A8I7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

519472:BHY08 RS06835
gene id: 519472:BHY08_RS06835
uniprot id: A0A1J0A6M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS08545
gene id: 519472:BHY08_RS08545
uniprot id: A0A1J0A8L8
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

519472:BHY08 RS09350
gene id: 519472:BHY08_RS09350
uniprot id: A0A1J0A7U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

519472:BHY08 RS00185
gene id: 519472:BHY08_RS00185
uniprot id: A0A1J0A3A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

519472:BHY08 RS05245
gene id: 519472:BHY08_RS05245
uniprot id: A0A1J0A5U1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS02565
gene id: 519472:BHY08_RS02565
uniprot id: A0A1J0A4H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

519472:BHY08 RS11175
gene id: 519472:BHY08_RS11175
uniprot id: A0A1J0A7L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

519472:BHY08 RS02585
gene id: 519472:BHY08_RS02585
uniprot id: A0A1J0A4E8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS09560
gene id: 519472:BHY08_RS09560
uniprot id: A0A1J0A7W8
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS01390
gene id: 519472:BHY08_RS01390
uniprot id: A0A1J0A8E0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

519472:BHY08 RS08410
gene id: 519472:BHY08_RS08410
uniprot id: A0A1J0A7C0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

519472:BHY08 RS09740
gene id: 519472:BHY08_RS09740
uniprot id: A0A1J0A831
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

519472:BHY08 RS04425
gene id: 519472:BHY08_RS04425
uniprot id: A0A1J0A5C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS10535
gene id: 519472:BHY08_RS10535
uniprot id: A0A1J0A8C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS03520
gene id: 519472:BHY08_RS03520
uniprot id: A0A1J0A506
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

519472:BHY08 RS02000
gene id: 519472:BHY08_RS02000
uniprot id: A0A1J0A448
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

519472:BHY08 RS02690
gene id: 519472:BHY08_RS02690
uniprot id: A0A1J0A4F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

519472:BHY08 RS02390
gene id: 519472:BHY08_RS02390
uniprot id: A0A1J0A498
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

519472:BHY08 RS09555
gene id: 519472:BHY08_RS09555
uniprot id: A0A1J0A801
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

519472:BHY08 RS02660
gene id: 519472:BHY08_RS02660
uniprot id: A0A1J0A4J3
names: Similarity
messages: Belongs to the TlyA family.

519472:BHY08 RS05875
gene id: 519472:BHY08_RS05875
uniprot id: A0A1J0A639
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS01450
gene id: 519472:BHY08_RS01450
uniprot id: A0A1J0A3U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

519472:BHY08 RS07885
gene id: 519472:BHY08_RS07885
uniprot id: A0A1J0A744
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

519472:BHY08 RS05375
gene id: 519472:BHY08_RS05375
uniprot id: A0A1J0A5U6
names: Similarity
messages: Belongs to the RutC family.

519472:BHY08 RS03025
gene id: 519472:BHY08_RS03025
uniprot id: A0A1J0A4M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS04470
gene id: 519472:BHY08_RS04470
uniprot id: A0A1J0A5D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

519472:BHY08 RS10165
gene id: 519472:BHY08_RS10165
uniprot id: A0A1J0A892
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

519472:BHY08 RS02725
gene id: 519472:BHY08_RS02725
uniprot id: A0A1J0A4G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

519472:BHY08 RS10620
gene id: 519472:BHY08_RS10620
uniprot id: A0A1J0A8Q1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

519472:BHY08 RS03295
gene id: 519472:BHY08_RS03295
uniprot id: A0A1J0A4T5
names: Similarity
messages: Belongs to the asparagine synthetase family.

519472:BHY08 RS10245
gene id: 519472:BHY08_RS10245
uniprot id: A0A1J0A8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

519472:BHY08 RS07350
gene id: 519472:BHY08_RS07350
uniprot id: A0A1J0A6W5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

519472:BHY08 RS09950
gene id: 519472:BHY08_RS09950
uniprot id: A0A1J0A864
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS00035
gene id: 519472:BHY08_RS00035
uniprot id: A0A1J0A366
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

519472:BHY08 RS06295
gene id: 519472:BHY08_RS06295
uniprot id: A0A1J0A6D9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS05975
gene id: 519472:BHY08_RS05975
uniprot id: A0A1J0A677
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

519472:BHY08 RS09485
gene id: 519472:BHY08_RS09485
uniprot id: A0A1J0A7W4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

519472:BHY08 RS05465
gene id: 519472:BHY08_RS05465
uniprot id: A0A1J0A8I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

519472:BHY08 RS09915
gene id: 519472:BHY08_RS09915
uniprot id: A0A1J0A827
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS01540
gene id: 519472:BHY08_RS01540
uniprot id: A0A1J0A3X5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

519472:BHY08 RS05680
gene id: 519472:BHY08_RS05680
uniprot id: A0A1J0A602
names: Subcellular Location Annotation
messages: Cytoplasm

519472:BHY08 RS08455
gene id: 519472:BHY08_RS08455
uniprot id: A0A1J0A7D0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

519472:BHY08 RS06640
gene id: 519472:BHY08_RS06640
uniprot id: A0A1J0A6G4
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS02885
gene id: 519472:BHY08_RS02885
uniprot id: A0A1J0A4N8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS05525
gene id: 519472:BHY08_RS05525
uniprot id: A0A1J0A5X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS08055
gene id: 519472:BHY08_RS08055
uniprot id: A0A1J0A786
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS04585
gene id: 519472:BHY08_RS04585
uniprot id: A0A1J0A5H9
names: Similarity
messages: Belongs to the peptidase S41A family.

519472:BHY08 RS05960
gene id: 519472:BHY08_RS05960
uniprot id: A0A1J0A655
names: Similarity
messages: Belongs to the fabD family.

519472:BHY08 RS02850
gene id: 519472:BHY08_RS02850
uniprot id: A0A1J0A4J5
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

519472:BHY08 RS08215
gene id: 519472:BHY08_RS08215
uniprot id: A0A1J0A7B1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

519472:BHY08 RS06235
gene id: 519472:BHY08_RS06235
uniprot id: A0A1J0A6A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

519472:BHY08 RS08730
gene id: 519472:BHY08_RS08730
uniprot id: A0A1J0A7H6
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07860
gene id: 519472:BHY08_RS07860
uniprot id: A0A1J0A730
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS10135
gene id: 519472:BHY08_RS10135
uniprot id: A0A1J0A882
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

519472:BHY08 RS05185
gene id: 519472:BHY08_RS05185
uniprot id: A0A1J0A5R8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

519472:BHY08 RS02755
gene id: 519472:BHY08_RS02755
uniprot id: A0A1J0A4K3
names: Subcellular Location Annotation
messages: Cytoplasm

519472:BHY08 RS02665
gene id: 519472:BHY08_RS02665
uniprot id: A0A1J0A4F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

519472:BHY08 RS08890
gene id: 519472:BHY08_RS08890
uniprot id: A0A1J0A7K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS08295
gene id: 519472:BHY08_RS08295
uniprot id: A0A1J0A7C5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

519472:BHY08 RS08855
gene id: 519472:BHY08_RS08855
uniprot id: A0A1J0A8M1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

519472:BHY08 RS00115
gene id: 519472:BHY08_RS00115
uniprot id: A0A1J0A377
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

519472:BHY08 RS08665
gene id: 519472:BHY08_RS08665
uniprot id: A0A1J0A7K0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

519472:BHY08 RS02145
gene id: 519472:BHY08_RS02145
uniprot id: A0A1J0A469
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS01185
gene id: 519472:BHY08_RS01185
uniprot id: A0A1J0A3Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

519472:BHY08 RS02520
gene id: 519472:BHY08_RS02520
uniprot id: A0A1J0A4E7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

519472:BHY08 RS05215
gene id: 519472:BHY08_RS05215
uniprot id: A0A1J0A5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

519472:BHY08 RS08620
gene id: 519472:BHY08_RS08620
uniprot id: A0A1J0A7H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

519472:BHY08 RS04610
gene id: 519472:BHY08_RS04610
uniprot id: A0A1J0A5G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

519472:BHY08 RS04650
gene id: 519472:BHY08_RS04650
uniprot id: A0A1J0A5G7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

519472:BHY08 RS06360
gene id: 519472:BHY08_RS06360
uniprot id: A0A1J0A6B9
names: Similarity
messages: Belongs to the IMPACT family.

519472:BHY08 RS03700
gene id: 519472:BHY08_RS03700
uniprot id: A0A1J0A535
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

519472:BHY08 RS07000
gene id: 519472:BHY08_RS07000
uniprot id: A0A1J0A6P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

519472:BHY08 RS09085
gene id: 519472:BHY08_RS09085
uniprot id: A0A1J0A7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

519472:BHY08 RS09050
gene id: 519472:BHY08_RS09050
uniprot id: A0A1J0A7R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

519472:BHY08 RS01745
gene id: 519472:BHY08_RS01745
uniprot id: A0A1J0A401
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

519472:BHY08 RS06550
gene id: 519472:BHY08_RS06550
uniprot id: A0A1J0A6F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

519472:BHY08 RS05360
gene id: 519472:BHY08_RS05360
uniprot id: A0A1J0A5W1
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

519472:BHY08 RS04320
gene id: 519472:BHY08_RS04320
uniprot id: A0A1J0A5B3
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS03550
gene id: 519472:BHY08_RS03550
uniprot id: A0A1J0A4W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

519472:BHY08 RS02705
gene id: 519472:BHY08_RS02705
uniprot id: A0A1J0A4G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS06715
gene id: 519472:BHY08_RS06715
uniprot id: A0A1J0A6K7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

519472:BHY08 RS05855
gene id: 519472:BHY08_RS05855
uniprot id: A0A1J0A656
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS06965
gene id: 519472:BHY08_RS06965
uniprot id: A0A1J0A6Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

519472:BHY08 RS03930
gene id: 519472:BHY08_RS03930
uniprot id: A0A1J0A570
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

519472:BHY08 RS00695
gene id: 519472:BHY08_RS00695
uniprot id: A0A1J0A3G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

519472:BHY08 RS03005
gene id: 519472:BHY08_RS03005
uniprot id: A0A1J0A4M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

519472:BHY08 RS03395
gene id: 519472:BHY08_RS03395
uniprot id: A0A1J0A4Y4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

519472:BHY08 RS05625
gene id: 519472:BHY08_RS05625
uniprot id: A0A1J0A5Y8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

519472:BHY08 RS02685
gene id: 519472:BHY08_RS02685
uniprot id: A0A1J0A4G1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

519472:BHY08 RS09920
gene id: 519472:BHY08_RS09920
uniprot id: A0A1J0A862
names: Subcellular Location Annotation
messages: Cytoplasm

519472:BHY08 RS05440
gene id: 519472:BHY08_RS05440
uniprot id: A0A1J0A5W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS09750
gene id: 519472:BHY08_RS09750
uniprot id: A0A1J0A820
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS09020
gene id: 519472:BHY08_RS09020
uniprot id: A0A1J0A7N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

519472:BHY08 RS08355
gene id: 519472:BHY08_RS08355
uniprot id: A0A1J0A7C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

519472:BHY08 RS05520
gene id: 519472:BHY08_RS05520
uniprot id: A0A1J0A5W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS09480
gene id: 519472:BHY08_RS09480
uniprot id: A0A1J0A7W5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

519472:BHY08 RS04510
gene id: 519472:BHY08_RS04510
uniprot id: A0A1J0A5G6
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS08380
gene id: 519472:BHY08_RS08380
uniprot id: A0A1J0A7B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

519472:BHY08 RS05640
gene id: 519472:BHY08_RS05640
uniprot id: A0A1J0A5Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

519472:BHY08 RS04765
gene id: 519472:BHY08_RS04765
uniprot id: A0A1J0A5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

519472:BHY08 RS07325
gene id: 519472:BHY08_RS07325
uniprot id: A0A1J0A6V0
names: Similarity
messages: Belongs to the ArsC family.

519472:BHY08 RS05630
gene id: 519472:BHY08_RS05630
uniprot id: A0A1J0A611
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Ycf16 family.
messages: Membrane

519472:BHY08 RS02920
gene id: 519472:BHY08_RS02920
uniprot id: A0A1J0A4K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS05945
gene id: 519472:BHY08_RS05945
uniprot id: A0A1J0A650
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

519472:BHY08 RS02180
gene id: 519472:BHY08_RS02180
uniprot id: A0A1J0A495
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

519472:BHY08 RS06880
gene id: 519472:BHY08_RS06880
uniprot id: A0A1J0A6N5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

519472:BHY08 RS00785
gene id: 519472:BHY08_RS00785
uniprot id: A0A1J0A3I3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

519472:BHY08 RS03315
gene id: 519472:BHY08_RS03315
uniprot id: A0A1J0A4X2
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

519472:BHY08 RS09135
gene id: 519472:BHY08_RS09135
uniprot id: A0A1J0A7S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

519472:BHY08 RS03065
gene id: 519472:BHY08_RS03065
uniprot id: A0A1J0A4N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

519472:BHY08 RS04265
gene id: 519472:BHY08_RS04265
uniprot id: A0A1J0A5A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

519472:BHY08 RS01975
gene id: 519472:BHY08_RS01975
uniprot id: A0A1J0A450
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

519472:BHY08 RS04005
gene id: 519472:BHY08_RS04005
uniprot id: A0A1J0A581
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

519472:BHY08 RS08600
gene id: 519472:BHY08_RS08600
uniprot id: A0A1J0A7F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

519472:BHY08 RS00135
gene id: 519472:BHY08_RS00135
uniprot id: A0A1J0A395
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

519472:BHY08 RS05320
gene id: 519472:BHY08_RS05320
uniprot id: A0A1J0A5V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

519472:BHY08 RS07765
gene id: 519472:BHY08_RS07765
uniprot id: A0A1J0A714
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

519472:BHY08 RS06155
gene id: 519472:BHY08_RS06155
uniprot id: A0A1J0A687
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519472:BHY08 RS04505
gene id: 519472:BHY08_RS04505
uniprot id: A0A1J0A5G3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

519472:BHY08 RS02010
gene id: 519472:BHY08_RS02010
uniprot id: A0A1J0A442
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS03710
gene id: 519472:BHY08_RS03710
uniprot id: A0A1J0A521
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

519472:BHY08 RS02895
gene id: 519472:BHY08_RS02895
uniprot id: A0A1J0A4K1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

519472:BHY08 RS05420
gene id: 519472:BHY08_RS05420
uniprot id: A0A1J0A5V6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

519472:BHY08 RS05310
gene id: 519472:BHY08_RS05310
uniprot id: A0A1J0A5V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

519472:BHY08 RS02915
gene id: 519472:BHY08_RS02915
uniprot id: A0A1J0A4P0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

519472:BHY08 RS02540
gene id: 519472:BHY08_RS02540
uniprot id: A0A1J0A4H8
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

519472:BHY08 RS02035
gene id: 519472:BHY08_RS02035
uniprot id: A0A1J0A488
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

519472:BHY08 RS02600
gene id: 519472:BHY08_RS02600
uniprot id: A0A1J0A4D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

519472:BHY08 RS05970
gene id: 519472:BHY08_RS05970
uniprot id: A0A1J0A654
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

519472:BHY08 RS08695
gene id: 519472:BHY08_RS08695
uniprot id: A0A1J0A7G0
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

519472:BHY08 RS06810
gene id: 519472:BHY08_RS06810
uniprot id: A0A1J0A6L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

519472:BHY08 RS04405
gene id: 519472:BHY08_RS04405
uniprot id: A0A1J0A8H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

519472:BHY08 RS03635
gene id: 519472:BHY08_RS03635
uniprot id: A0A1J0A4Z0
names: Similarity
messages: Belongs to the ribF family.

519472:BHY08 RS02730
gene id: 519472:BHY08_RS02730
uniprot id: A0A1J0A4G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

519472:BHY08 RS06410
gene id: 519472:BHY08_RS06410
uniprot id: A0A1J0A6D8
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS01850
gene id: 519472:BHY08_RS01850
uniprot id: A0A1J0A429
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

519472:BHY08 RS02645
gene id: 519472:BHY08_RS02645
uniprot id: A0A1J0A4F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

519472:BHY08 RS08130
gene id: 519472:BHY08_RS08130
uniprot id: A0A1J0A7A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell membrane
messages: Membrane
messages: O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein.

519472:BHY08 RS04025
gene id: 519472:BHY08_RS04025
uniprot id: A0A1J0A580
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

519472:BHY08 RS03555
gene id: 519472:BHY08_RS03555
uniprot id: A0A1J0A4Y3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

519472:BHY08 RS01045
gene id: 519472:BHY08_RS01045
uniprot id: A0A1J0A3M9
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS00260
gene id: 519472:BHY08_RS00260
uniprot id: A0A1J0A3A7
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS09440
gene id: 519472:BHY08_RS09440
uniprot id: A0A1J0A7V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

519472:BHY08 RS01225
gene id: 519472:BHY08_RS01225
uniprot id: A0A1J0A3R4
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS00045
gene id: 519472:BHY08_RS00045
uniprot id: A0A1J0A355
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

519472:BHY08 RS05325
gene id: 519472:BHY08_RS05325
uniprot id: A0A1J0A5V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

519472:BHY08 RS09005
gene id: 519472:BHY08_RS09005
uniprot id: A0A1J0A7M7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

519472:BHY08 RS06795
gene id: 519472:BHY08_RS06795
uniprot id: A0A1J0A6M3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

519472:BHY08 RS02045
gene id: 519472:BHY08_RS02045
uniprot id: A0A1J0A454
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

519472:BHY08 RS09850
gene id: 519472:BHY08_RS09850
uniprot id: A0A1J0A837
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cell envelope
messages: Releases the N-terminal proline from various substrates.

519472:BHY08 RS08260
gene id: 519472:BHY08_RS08260
uniprot id: A0A1J0A7B4
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

519472:BHY08 RS04210
gene id: 519472:BHY08_RS04210
uniprot id: A0A1J0A587
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS05095
gene id: 519472:BHY08_RS05095
uniprot id: A0A1J0A5R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

519472:BHY08 RS00005
gene id: 519472:BHY08_RS00005
uniprot id: A0A1J0A356
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

519472:BHY08 RS06275
gene id: 519472:BHY08_RS06275
uniprot id: A0A1J0A6A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

519472:BHY08 RS06770
gene id: 519472:BHY08_RS06770
uniprot id: A0A1J0A6K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

519472:BHY08 RS00215
gene id: 519472:BHY08_RS00215
uniprot id: A0A1J0A396
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS03170
gene id: 519472:BHY08_RS03170
uniprot id: A0A1J0A4V2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

519472:BHY08 RS09420
gene id: 519472:BHY08_RS09420
uniprot id: A0A1J0A7U5
names: Similarity
messages: Belongs to the ycf81 family.

519472:BHY08 RS01930
gene id: 519472:BHY08_RS01930
uniprot id: A0A1J0A424
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

519472:BHY08 RS05335
gene id: 519472:BHY08_RS05335
uniprot id: A0A1J0A5T5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS08525
gene id: 519472:BHY08_RS08525
uniprot id: A0A1J0A7G9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

519472:BHY08 RS09895
gene id: 519472:BHY08_RS09895
uniprot id: A0A1J0A821
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519472:BHY08 RS10130
gene id: 519472:BHY08_RS10130
uniprot id: A0A1J0A899
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

519472:BHY08 RS10195
gene id: 519472:BHY08_RS10195
uniprot id: A0A1J0A8A7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

519472:BHY08 RS04270
gene id: 519472:BHY08_RS04270
uniprot id: A0A1J0A5C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

519472:BHY08 RS03565
gene id: 519472:BHY08_RS03565
uniprot id: A0A1J0A514
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

519472:BHY08 RS03440
gene id: 519472:BHY08_RS03440
uniprot id: A0A1J0A4U6
names: Similarity
messages: Belongs to the peptidase S16 family.

519472:BHY08 RS08950
gene id: 519472:BHY08_RS08950
uniprot id: A0A1J0A7L8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

519472:BHY08 RS06405
gene id: 519472:BHY08_RS06405
uniprot id: A0A1J0A8H0
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS04325
gene id: 519472:BHY08_RS04325
uniprot id: A0A1J0A5A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS00060
gene id: 519472:BHY08_RS00060
uniprot id: A0A1J0A381
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

519472:BHY08 RS08345
gene id: 519472:BHY08_RS08345
uniprot id: A0A1J0A7D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

519472:BHY08 RS04550
gene id: 519472:BHY08_RS04550
uniprot id: A0A1J0A5H2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

519472:BHY08 RS09445
gene id: 519472:BHY08_RS09445
uniprot id: A0A1J0A7T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

519472:BHY08 RS00255
gene id: 519472:BHY08_RS00255
uniprot id: A0A1J0A3A6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS06995
gene id: 519472:BHY08_RS06995
uniprot id: A0A1J0A6M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

519472:BHY08 RS04415
gene id: 519472:BHY08_RS04415
uniprot id: A0A1J0A5D1
names: Similarity
messages: Belongs to the type IA topoisomerase family.

519472:BHY08 RS04240
gene id: 519472:BHY08_RS04240
uniprot id: A0A1J0A597
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

519472:BHY08 RS00155
gene id: 519472:BHY08_RS00155
uniprot id: A0A1J0A385
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS08755
gene id: 519472:BHY08_RS08755
uniprot id: A0A1J0A7L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

519472:BHY08 RS08830
gene id: 519472:BHY08_RS08830
uniprot id: A0A1J0A7K2
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS10555
gene id: 519472:BHY08_RS10555
uniprot id: A0A1J0A8B1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

519472:BHY08 RS03165
gene id: 519472:BHY08_RS03165
uniprot id: A0A1J0A4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

519472:BHY08 RS00745
gene id: 519472:BHY08_RS00745
uniprot id: A0A1J0A3H6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

519472:BHY08 RS06605
gene id: 519472:BHY08_RS06605
uniprot id: A0A1J0A6G5
names: Similarity
messages: Belongs to the sigma-54 factor family.

519472:BHY08 RS05725
gene id: 519472:BHY08_RS05725
uniprot id: A0A1J0A610
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

519472:BHY08 RS03720
gene id: 519472:BHY08_RS03720
uniprot id: A0A1J0A510
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS02650
gene id: 519472:BHY08_RS02650
uniprot id: A0A1J0A4E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

519472:BHY08 RS02445
gene id: 519472:BHY08_RS02445
uniprot id: A0A1J0A4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

519472:BHY08 RS01800
gene id: 519472:BHY08_RS01800
uniprot id: A0A1J0A3Z9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

519472:BHY08 RS09875
gene id: 519472:BHY08_RS09875
uniprot id: A0A1J0A855
names: Similarity
messages: Belongs to the peptidase C69 family.

519472:BHY08 RS05400
gene id: 519472:BHY08_RS05400
uniprot id: A0A1J0A5V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

519472:BHY08 RS02120
gene id: 519472:BHY08_RS02120
uniprot id: A0A1J0A457
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

519472:BHY08 RS02295
gene id: 519472:BHY08_RS02295
uniprot id: A0A1J0A494
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

519472:BHY08 RS00015
gene id: 519472:BHY08_RS00015
uniprot id: A0A1J0A372
names: Similarity
messages: Belongs to the glutathione peroxidase family.

519472:BHY08 RS09270
gene id: 519472:BHY08_RS09270
uniprot id: A0A1J0A7S3
names: Subcellular Location Annotation
messages: Cytoplasm

519472:BHY08 RS02210
gene id: 519472:BHY08_RS02210
uniprot id: A0A1J0A4A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS06830
gene id: 519472:BHY08_RS06830
uniprot id: A0A1J0A6L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS01155
gene id: 519472:BHY08_RS01155
uniprot id: A0A1J0A3R6
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07710
gene id: 519472:BHY08_RS07710
uniprot id: A0A1J0A731
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

519472:BHY08 RS04075
gene id: 519472:BHY08_RS04075
uniprot id: A0A1J0A558
names: Similarity
messages: Belongs to the HAM1 NTPase family.

519472:BHY08 RS06175
gene id: 519472:BHY08_RS06175
uniprot id: A0A1J0A6B0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

519472:BHY08 RS04000
gene id: 519472:BHY08_RS04000
uniprot id: A0A1J0A552
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

519472:BHY08 RS04970
gene id: 519472:BHY08_RS04970
uniprot id: A0A1J0A8H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

519472:BHY08 RS01920
gene id: 519472:BHY08_RS01920
uniprot id: A0A1J0A435
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

519472:BHY08 RS08945
gene id: 519472:BHY08_RS08945
uniprot id: A0A1J0A7P2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

519472:BHY08 RS07225
gene id: 519472:BHY08_RS07225
uniprot id: A0A1J0A6T6
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07930
gene id: 519472:BHY08_RS07930
uniprot id: A0A1J0A738
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

519472:BHY08 RS02075
gene id: 519472:BHY08_RS02075
uniprot id: A0A1J0A480
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

519472:BHY08 RS01230
gene id: 519472:BHY08_RS01230
uniprot id: A0A1J0A3R9
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS08330
gene id: 519472:BHY08_RS08330
uniprot id: A0A1J0A7A8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

519472:BHY08 RS03975
gene id: 519472:BHY08_RS03975
uniprot id: A0A1J0A567
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

519472:BHY08 RS08390
gene id: 519472:BHY08_RS08390
uniprot id: A0A1J0A7E4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS05025
gene id: 519472:BHY08_RS05025
uniprot id: A0A1J0A5N5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

519472:BHY08 RS06595
gene id: 519472:BHY08_RS06595
uniprot id: A0A1J0A6G7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

519472:BHY08 RS00395
gene id: 519472:BHY08_RS00395
uniprot id: A0A1J0A3D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

519472:BHY08 RS08165
gene id: 519472:BHY08_RS08165
uniprot id: A0A1J0A794
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

519472:BHY08 RS00950
gene id: 519472:BHY08_RS00950
uniprot id: A0A1J0A3K5
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS02555
gene id: 519472:BHY08_RS02555
uniprot id: A0A1J0A4D0
names: Subcellular Location Annotation
messages: Cytoplasm

519472:BHY08 RS00885
gene id: 519472:BHY08_RS00885
uniprot id: A0A1J0A3K1
names: Similarity
messages: Belongs to the asp23 family.

519472:BHY08 RS08900
gene id: 519472:BHY08_RS08900
uniprot id: A0A1J0A7N6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

519472:BHY08 RS01400
gene id: 519472:BHY08_RS01400
uniprot id: A0A1J0A3U7
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

519472:BHY08 RS03410
gene id: 519472:BHY08_RS03410
uniprot id: A0A1J0A4Y5
names: Function
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

519472:BHY08 RS03055
gene id: 519472:BHY08_RS03055
uniprot id: A0A1J0A4P7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

519472:BHY08 RS02025
gene id: 519472:BHY08_RS02025
uniprot id: A0A1J0A445
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS10540
gene id: 519472:BHY08_RS10540
uniprot id: A0A1J0A8C1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS08255
gene id: 519472:BHY08_RS08255
uniprot id: A0A1J0A7B9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

519472:BHY08 RS00200
gene id: 519472:BHY08_RS00200
uniprot id: A0A1J0A393
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07330
gene id: 519472:BHY08_RS07330
uniprot id: A0A1J0A6T4
names: Similarity
messages: Belongs to the DtxR/MntR family.

519472:BHY08 RS00600
gene id: 519472:BHY08_RS00600
uniprot id: A0A1J0A3E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS07060
gene id: 519472:BHY08_RS07060
uniprot id: A0A1J0A6P2
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Divalent metal ions. Mg(2+) is the most effective.

519472:BHY08 RS09745
gene id: 519472:BHY08_RS09745
uniprot id: A0A1J0A811
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

519472:BHY08 RS06760
gene id: 519472:BHY08_RS06760
uniprot id: A0A1J0A6L4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

519472:BHY08 RS08320
gene id: 519472:BHY08_RS08320
uniprot id: A0A1J0A7B3
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

519472:BHY08 RS04060
gene id: 519472:BHY08_RS04060
uniprot id: A0A1J0A582
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

519472:BHY08 RS04080
gene id: 519472:BHY08_RS04080
uniprot id: A0A1J0A569
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

519472:BHY08 RS09380
gene id: 519472:BHY08_RS09380
uniprot id: A0A1J0A7T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS02400
gene id: 519472:BHY08_RS02400
uniprot id: A0A1J0A4D7
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS05660
gene id: 519472:BHY08_RS05660
uniprot id: A0A1J0A619
names: Function
names: Subunit
messages: Catalyzes the conversion of a range of fructosamine 6-phosphates to glucose 6-phosphate and a free amino acid.
messages: Homooctamer.

519472:BHY08 RS02625
gene id: 519472:BHY08_RS02625
uniprot id: A0A1J0A4H4
names: Similarity
messages: Belongs to the asp23 family.

519472:BHY08 RS07905
gene id: 519472:BHY08_RS07905
uniprot id: A0A1J0A735
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07175
gene id: 519472:BHY08_RS07175
uniprot id: A0A1J0A6R3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

519472:BHY08 RS00025
gene id: 519472:BHY08_RS00025
uniprot id: A0A1J0A373
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

519472:BHY08 RS04705
gene id: 519472:BHY08_RS04705
uniprot id: A0A1J0A5H6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

519472:BHY08 RS08120
gene id: 519472:BHY08_RS08120
uniprot id: A0A1J0A772
names: Similarity
messages: Belongs to the DltD family.

519472:BHY08 RS06825
gene id: 519472:BHY08_RS06825
uniprot id: A0A1J0A6N2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

519472:BHY08 RS07530
gene id: 519472:BHY08_RS07530
uniprot id: A0A1J0A6Y8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS06575
gene id: 519472:BHY08_RS06575
uniprot id: A0A1J0A6G0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

519472:BHY08 RS08865
gene id: 519472:BHY08_RS08865
uniprot id: A0A1J0A7K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

519472:BHY08 RS05550
gene id: 519472:BHY08_RS05550
uniprot id: A0A1J0A5Z9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

519472:BHY08 RS06290
gene id: 519472:BHY08_RS06290
uniprot id: A0A1J0A6B2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519472:BHY08 RS05470
gene id: 519472:BHY08_RS05470
uniprot id: A0A1J0A5W7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

519472:BHY08 RS06725
gene id: 519472:BHY08_RS06725
uniprot id: A0A1J0A6I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

519472:BHY08 RS04445
gene id: 519472:BHY08_RS04445
uniprot id: A0A1J0A5D5
names: Similarity
messages: Belongs to the UPF0178 family.

519472:BHY08 RS05265
gene id: 519472:BHY08_RS05265
uniprot id: A0A1J0A5S3
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07030
gene id: 519472:BHY08_RS07030
uniprot id: A0A1J0A6R1
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS04280
gene id: 519472:BHY08_RS04280
uniprot id: A0A1J0A5A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

519472:BHY08 RS06285
gene id: 519472:BHY08_RS06285
uniprot id: A0A1J0A8J7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519472:BHY08 RS05645
gene id: 519472:BHY08_RS05645
uniprot id: A0A1J0A5Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS09160
gene id: 519472:BHY08_RS09160
uniprot id: A0A1J0A7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

519472:BHY08 RS03645
gene id: 519472:BHY08_RS03645
uniprot id: A0A1J0A4Z7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

519472:BHY08 RS08135
gene id: 519472:BHY08_RS08135
uniprot id: A0A1J0A776
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
messages: Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

519472:BHY08 RS05285
gene id: 519472:BHY08_RS05285
uniprot id: A0A1J0A5U9
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

519472:BHY08 RS06130
gene id: 519472:BHY08_RS06130
uniprot id: A0A1J0A6A1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

519472:BHY08 RS05865
gene id: 519472:BHY08_RS05865
uniprot id: A0A1J0A641
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

519472:BHY08 RS06780
gene id: 519472:BHY08_RS06780
uniprot id: A0A1J0A6J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

519472:BHY08 RS10230
gene id: 519472:BHY08_RS10230
uniprot id: A0A1J0A895
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

519472:BHY08 RS00810
gene id: 519472:BHY08_RS00810
uniprot id: A0A1J0A3J2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

519472:BHY08 RS10175
gene id: 519472:BHY08_RS10175
uniprot id: A0A1J0A889
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

519472:BHY08 RS07255
gene id: 519472:BHY08_RS07255
uniprot id: A0A1J0A6V1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

519472:BHY08 RS08835
gene id: 519472:BHY08_RS08835
uniprot id: A0A1J0A7J5
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

519472:BHY08 RS02370
gene id: 519472:BHY08_RS02370
uniprot id: A0A1J0A4E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

519472:BHY08 RS03100
gene id: 519472:BHY08_RS03100
uniprot id: A0A1J0A4Q6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

519472:BHY08 RS00755
gene id: 519472:BHY08_RS00755
uniprot id: A0A1J0A3I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

519472:BHY08 RS04960
gene id: 519472:BHY08_RS04960
uniprot id: A0A1J0A5P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

519472:BHY08 RS00425
gene id: 519472:BHY08_RS00425
uniprot id: A0A1J0A3D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

519472:BHY08 RS05385
gene id: 519472:BHY08_RS05385
uniprot id: A0A1J0A5U5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS07950
gene id: 519472:BHY08_RS07950
uniprot id: A0A1J0A774
names: Similarity
messages: Belongs to the ABC transporter superfamily.

519472:BHY08 RS00105
gene id: 519472:BHY08_RS00105
uniprot id: A0A1J0A390
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

519472:BHY08 RS08250
gene id: 519472:BHY08_RS08250
uniprot id: A0A1J0A7B8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

519472:BHY08 RS07015
gene id: 519472:BHY08_RS07015
uniprot id: A0A1J0A6N4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

519472:BHY08 RS03060
gene id: 519472:BHY08_RS03060
uniprot id: A0A1J0A4R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

519472:BHY08 RS00855
gene id: 519472:BHY08_RS00855
uniprot id: A0A1J0A3K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS03775
gene id: 519472:BHY08_RS03775
uniprot id: A0A1J0A508
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

519472:BHY08 RS07460
gene id: 519472:BHY08_RS07460
uniprot id: A0A1J0A6W2
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Belongs to the GARS family.

519472:BHY08 RS08530
gene id: 519472:BHY08_RS08530
uniprot id: A0A1J0A7G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

519472:BHY08 RS04625
gene id: 519472:BHY08_RS04625
uniprot id: A0A1J0A5H1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

519472:BHY08 RS01525
gene id: 519472:BHY08_RS01525
uniprot id: A0A1J0A3X0
names: Function
messages: Involved in the transposition of the insertion sequence.

519472:BHY08 RS02715
gene id: 519472:BHY08_RS02715
uniprot id: A0A1J0A4L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS06030
gene id: 519472:BHY08_RS06030
uniprot id: A0A1J0A691
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

519472:BHY08 RS03360
gene id: 519472:BHY08_RS03360
uniprot id: A0A1J0A4T3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

519472:BHY08 RS06315
gene id: 519472:BHY08_RS06315
uniprot id: A0A1J0A6B1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

519472:BHY08 RS06330
gene id: 519472:BHY08_RS06330
uniprot id: A0A1J0A6D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

519472:BHY08 RS01505
gene id: 519472:BHY08_RS01505
uniprot id: A0A1J0A3V4
names: Similarity
messages: Belongs to the RNase H family.

519472:BHY08 RS09710
gene id: 519472:BHY08_RS09710
uniprot id: A0A1J0A7Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

519472:BHY08 RS09285
gene id: 519472:BHY08_RS09285
uniprot id: A0A1J0A7V3
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

519472:BHY08 RS00985
gene id: 519472:BHY08_RS00985
uniprot id: A0A1J0A3M5
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

519472:BHY08 RS00280
gene id: 519472:BHY08_RS00280
uniprot id: A0A1J0A3B3
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07915
gene id: 519472:BHY08_RS07915
uniprot id: A0A1J0A766
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

519472:BHY08 RS02355
gene id: 519472:BHY08_RS02355
uniprot id: A0A1J0A4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

519472:BHY08 RS10275
gene id: 519472:BHY08_RS10275
uniprot id: A0A1J0A8A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

519472:BHY08 RS08075
gene id: 519472:BHY08_RS08075
uniprot id: A0A1J0A765
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

519472:BHY08 RS03900
gene id: 519472:BHY08_RS03900
uniprot id: A0A1J0A524
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

519472:BHY08 RS03320
gene id: 519472:BHY08_RS03320
uniprot id: A0A1J0A4T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

519472:BHY08 RS05560
gene id: 519472:BHY08_RS05560
uniprot id: A0A1J0A5Y0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

519472:BHY08 RS04370
gene id: 519472:BHY08_RS04370
uniprot id: A0A1J0A5C2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

519472:BHY08 RS00575
gene id: 519472:BHY08_RS00575
uniprot id: A0A1J0A3E1
names: Similarity
messages: Belongs to the CtsR family.

519472:BHY08 RS05415
gene id: 519472:BHY08_RS05415
uniprot id: A0A1J0A5V5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

519472:BHY08 RS03250
gene id: 519472:BHY08_RS03250
uniprot id: A0A1J0A4T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

519472:BHY08 RS04805
gene id: 519472:BHY08_RS04805
uniprot id: A0A1J0A5L4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

519472:BHY08 RS09345
gene id: 519472:BHY08_RS09345
uniprot id: A0A1J0A7W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

519472:BHY08 RS06695
gene id: 519472:BHY08_RS06695
uniprot id: A0A1J0A6I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

519472:BHY08 RS06865
gene id: 519472:BHY08_RS06865
uniprot id: A0A1J0A6K9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

519472:BHY08 RS04385
gene id: 519472:BHY08_RS04385
uniprot id: A0A1J0A5F0
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS06720
gene id: 519472:BHY08_RS06720
uniprot id: A0A1J0A6K6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

519472:BHY08 RS09735
gene id: 519472:BHY08_RS09735
uniprot id: A0A1J0A7Z8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS08585
gene id: 519472:BHY08_RS08585
uniprot id: A0A1J0A7G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

519472:BHY08 RS03885
gene id: 519472:BHY08_RS03885
uniprot id: A0A1J0A528
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

519472:BHY08 RS05695
gene id: 519472:BHY08_RS05695
uniprot id: A0A1J0A605
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

519472:BHY08 RS04225
gene id: 519472:BHY08_RS04225
uniprot id: A0A1J0A5B4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

519472:BHY08 RS05505
gene id: 519472:BHY08_RS05505
uniprot id: A0A1J0A5Z2
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS04935
gene id: 519472:BHY08_RS04935
uniprot id: A0A1J0A5L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

519472:BHY08 RS07160
gene id: 519472:BHY08_RS07160
uniprot id: A0A1J0A6R5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

519472:BHY08 RS03940
gene id: 519472:BHY08_RS03940
uniprot id: A0A1J0A540
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

519472:BHY08 RS03780
gene id: 519472:BHY08_RS03780
uniprot id: A0A1J0A520
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

519472:BHY08 RS01030
gene id: 519472:BHY08_RS01030
uniprot id: A0A1J0A3N0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

519472:BHY08 RS08725
gene id: 519472:BHY08_RS08725
uniprot id: A0A1J0A7I1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

519472:BHY08 RS02945
gene id: 519472:BHY08_RS02945
uniprot id: A0A1J0A4J9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

519472:BHY08 RS01960
gene id: 519472:BHY08_RS01960
uniprot id: A0A1J0A440
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

519472:BHY08 RS10600
gene id: 519472:BHY08_RS10600
uniprot id: A0A1J0A8R1
names: Function
messages: Involved in the transposition of the insertion sequence.

519472:BHY08 RS09830
gene id: 519472:BHY08_RS09830
uniprot id: A0A1J0A836
names: Similarity
messages: Belongs to the UPF0213 family.

519472:BHY08 RS03665
gene id: 519472:BHY08_RS03665
uniprot id: A0A1J0A513
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

519472:BHY08 RS01770
gene id: 519472:BHY08_RS01770
uniprot id: A0A1J0A413
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS06420
gene id: 519472:BHY08_RS06420
uniprot id: A0A1J0A6D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

519472:BHY08 RS05210
gene id: 519472:BHY08_RS05210
uniprot id: A0A1J0A5R4
names: Similarity
messages: Belongs to the asp23 family.

519472:BHY08 RS06170
gene id: 519472:BHY08_RS06170
uniprot id: A0A1J0A6B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

519472:BHY08 RS07955
gene id: 519472:BHY08_RS07955
uniprot id: A0A1J0A770
names: Similarity
messages: Belongs to the ABC transporter superfamily.

519472:BHY08 RS03715
gene id: 519472:BHY08_RS03715
uniprot id: A0A1J0A542
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

519472:BHY08 RS08645
gene id: 519472:BHY08_RS08645
uniprot id: A0A1J0A7F7
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS04480
gene id: 519472:BHY08_RS04480
uniprot id: A0A1J0A5D8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

519472:BHY08 RS11370
gene id: 519472:BHY08_RS11370
uniprot id: A0A1J0A7I6
names: Similarity
messages: Belongs to the peptidase C40 family.

519472:BHY08 RS05790
gene id: 519472:BHY08_RS05790
uniprot id: A0A1J0A621
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

519472:BHY08 RS03245
gene id: 519472:BHY08_RS03245
uniprot id: A0A1J0A4R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

519472:BHY08 RS03285
gene id: 519472:BHY08_RS03285
uniprot id: A0A1J0A4S3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

519472:BHY08 RS02880
gene id: 519472:BHY08_RS02880
uniprot id: A0A1J0A4M7
names: Similarity
messages: Belongs to the peptidase S8 family.

519472:BHY08 RS10190
gene id: 519472:BHY08_RS10190
uniprot id: A0A1J0A875
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

519472:BHY08 RS09945
gene id: 519472:BHY08_RS09945
uniprot id: A0A1J0A844
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS10105
gene id: 519472:BHY08_RS10105
uniprot id: A0A1J0A863
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

519472:BHY08 RS05950
gene id: 519472:BHY08_RS05950
uniprot id: A0A1J0A658
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

519472:BHY08 RS02785
gene id: 519472:BHY08_RS02785
uniprot id: A0A1J0A4L5
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS09415
gene id: 519472:BHY08_RS09415
uniprot id: A0A1J0A7X8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

519472:BHY08 RS05870
gene id: 519472:BHY08_RS05870
uniprot id: A0A1J0A631
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

519472:BHY08 RS06525
gene id: 519472:BHY08_RS06525
uniprot id: A0A1J0A6H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

519472:BHY08 RS00595
gene id: 519472:BHY08_RS00595
uniprot id: A0A1J0A3D5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

519472:BHY08 RS00145
gene id: 519472:BHY08_RS00145
uniprot id: A0A1J0A3A0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

519472:BHY08 RS00335
gene id: 519472:BHY08_RS00335
uniprot id: A0A1J0A3C6
names: Similarity
messages: Belongs to the EamA transporter family.

519472:BHY08 RS06675
gene id: 519472:BHY08_RS06675
uniprot id: A0A1J0A6J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

519472:BHY08 RS02610
gene id: 519472:BHY08_RS02610
uniprot id: A0A1J0A4I5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

519472:BHY08 RS02020
gene id: 519472:BHY08_RS02020
uniprot id: A0A1J0A468
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS02365
gene id: 519472:BHY08_RS02365
uniprot id: A0A1J0A4C1
names: Similarity
messages: Belongs to the UPF0297 family.

519472:BHY08 RS08180
gene id: 519472:BHY08_RS08180
uniprot id: A0A1J0A781
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

519472:BHY08 RS07740
gene id: 519472:BHY08_RS07740
uniprot id: A0A1J0A718
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

519472:BHY08 RS03185
gene id: 519472:BHY08_RS03185
uniprot id: A0A1J0A4U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

519472:BHY08 RS09800
gene id: 519472:BHY08_RS09800
uniprot id: A0A1J0A825
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS01260
gene id: 519472:BHY08_RS01260
uniprot id: A0A1J0A3R8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

519472:BHY08 RS03210
gene id: 519472:BHY08_RS03210
uniprot id: A0A1J0A4V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS04990
gene id: 519472:BHY08_RS04990
uniprot id: A0A1J0A5M2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

519472:BHY08 RS03475
gene id: 519472:BHY08_RS03475
uniprot id: A0A1J0A4X0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

519472:BHY08 RS03190
gene id: 519472:BHY08_RS03190
uniprot id: A0A1J0A4R7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

519472:BHY08 RS09330
gene id: 519472:BHY08_RS09330
uniprot id: A0A1J0A7S1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

519472:BHY08 RS00265
gene id: 519472:BHY08_RS00265
uniprot id: A0A1J0A3B7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

519472:BHY08 RS04885
gene id: 519472:BHY08_RS04885
uniprot id: A0A1J0A5K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

519472:BHY08 RS09045
gene id: 519472:BHY08_RS09045
uniprot id: A0A1J0A7M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

519472:BHY08 RS02460
gene id: 519472:BHY08_RS02460
uniprot id: A0A1J0A4G2
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

519472:BHY08 RS03660
gene id: 519472:BHY08_RS03660
uniprot id: A0A1J0A4Y9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

519472:BHY08 RS07105
gene id: 519472:BHY08_RS07105
uniprot id: A0A1J0A6S5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

519472:BHY08 RS00605
gene id: 519472:BHY08_RS00605
uniprot id: A0A1J0A3E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

519472:BHY08 RS09725
gene id: 519472:BHY08_RS09725
uniprot id: A0A1J0A7Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

519472:BHY08 RS05860
gene id: 519472:BHY08_RS05860
uniprot id: A0A1J0A634
names: Similarity
messages: Belongs to the threonine synthase family.

519472:BHY08 RS09505
gene id: 519472:BHY08_RS09505
uniprot id: A0A1J0A7W3
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

519472:BHY08 RS02580
gene id: 519472:BHY08_RS02580
uniprot id: A0A1J0A4I3
names: Similarity
messages: Belongs to the FBPase class 3 family.

519472:BHY08 RS01815
gene id: 519472:BHY08_RS01815
uniprot id: A0A1J0A404
names: Similarity
messages: Belongs to the Nudix hydrolase family.

519472:BHY08 RS04515
gene id: 519472:BHY08_RS04515
uniprot id: A0A1J0A5E5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

519472:BHY08 RS09355
gene id: 519472:BHY08_RS09355
uniprot id: A0A1J0A7U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

519472:BHY08 RS08630
gene id: 519472:BHY08_RS08630
uniprot id: A0A1J0A7H1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

519472:BHY08 RS05575
gene id: 519472:BHY08_RS05575
uniprot id: A0A1J0A606
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

519472:BHY08 RS09255
gene id: 519472:BHY08_RS09255
uniprot id: A0A1J0A7T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

519472:BHY08 RS09410
gene id: 519472:BHY08_RS09410
uniprot id: A0A1J0A7T6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

519472:BHY08 RS01300
gene id: 519472:BHY08_RS01300
uniprot id: A0A1J0A3S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

519472:BHY08 RS02345
gene id: 519472:BHY08_RS02345
uniprot id: A0A1J0A490
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

519472:BHY08 RS06800
gene id: 519472:BHY08_RS06800
uniprot id: A0A1J0A6M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

519472:BHY08 RS10250
gene id: 519472:BHY08_RS10250
uniprot id: A0A1J0A898
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

519472:BHY08 RS03435
gene id: 519472:BHY08_RS03435
uniprot id: A0A1J0A4Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

519472:BHY08 RS10550
gene id: 519472:BHY08_RS10550
uniprot id: A0A1J0A8D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

519472:BHY08 RS03730
gene id: 519472:BHY08_RS03730
uniprot id: A0A1J0A4Z9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

519472:BHY08 RS08240
gene id: 519472:BHY08_RS08240
uniprot id: A0A1J0A7B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

519472:BHY08 RS08445
gene id: 519472:BHY08_RS08445
uniprot id: A0A1J0A7D9
names: Similarity
messages: Belongs to the UPF0177 family.

519472:BHY08 RS09535
gene id: 519472:BHY08_RS09535
uniprot id: A0A1J0A7X4
names: Similarity
messages: Belongs to the ThiD family.

519472:BHY08 RS00120
gene id: 519472:BHY08_RS00120
uniprot id: A0A1J0A379
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS07935
gene id: 519472:BHY08_RS07935
uniprot id: A0A1J0A737
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

519472:BHY08 RS02090
gene id: 519472:BHY08_RS02090
uniprot id: A0A1J0A464
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS07355
gene id: 519472:BHY08_RS07355
uniprot id: A0A1J0A6W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

519472:BHY08 RS09815
gene id: 519472:BHY08_RS09815
uniprot id: A0A1J0A812
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

519472:BHY08 RS08125
gene id: 519472:BHY08_RS08125
uniprot id: A0A1J0A771
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
messages: Belongs to the DltC family.
messages: Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
messages: Cytoplasm

519472:BHY08 RS06600
gene id: 519472:BHY08_RS06600
uniprot id: A0A1J0A6F8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

519472:BHY08 RS10265
gene id: 519472:BHY08_RS10265
uniprot id: A0A1J0A8A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

519472:BHY08 RS08570
gene id: 519472:BHY08_RS08570
uniprot id: A0A1J0A8J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS10225
gene id: 519472:BHY08_RS10225
uniprot id: A0A1J0A8A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

519472:BHY08 RS10210
gene id: 519472:BHY08_RS10210
uniprot id: A0A1J0A896
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

519472:BHY08 RS09930
gene id: 519472:BHY08_RS09930
uniprot id: A0A1J0A849
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

519472:BHY08 RS02740
gene id: 519472:BHY08_RS02740
uniprot id: A0A1J0A4J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

519472:BHY08 RS04215
gene id: 519472:BHY08_RS04215
uniprot id: A0A1J0A5C3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

519472:BHY08 RS07815
gene id: 519472:BHY08_RS07815
uniprot id: A0A1J0A740
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS04855
gene id: 519472:BHY08_RS04855
uniprot id: A0A1J0A5L2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

519472:BHY08 RS06615
gene id: 519472:BHY08_RS06615
uniprot id: A0A1J0A6I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

519472:BHY08 RS02375
gene id: 519472:BHY08_RS02375
uniprot id: A0A1J0A4A7
names: Similarity
messages: Belongs to the UPF0473 family.

519472:BHY08 RS00385
gene id: 519472:BHY08_RS00385
uniprot id: A0A1J0A3D0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

519472:BHY08 RS08080
gene id: 519472:BHY08_RS08080
uniprot id: A0A1J0A793
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

519472:BHY08 RS09510
gene id: 519472:BHY08_RS09510
uniprot id: A0A1J0A7V5
names: Similarity
messages: Belongs to the DapB family.

519472:BHY08 RS02905
gene id: 519472:BHY08_RS02905
uniprot id: A0A1J0A4J4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS03530
gene id: 519472:BHY08_RS03530
uniprot id: A0A1J0A4Y6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS05990
gene id: 519472:BHY08_RS05990
uniprot id: A0A1J0A666
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

519472:BHY08 RS02195
gene id: 519472:BHY08_RS02195
uniprot id: A0A1J0A479
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

519472:BHY08 RS04655
gene id: 519472:BHY08_RS04655
uniprot id: A0A1J0A5G8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

519472:BHY08 RS06305
gene id: 519472:BHY08_RS06305
uniprot id: A0A1J0A6A8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

519472:BHY08 RS09195
gene id: 519472:BHY08_RS09195
uniprot id: A0A1J0A7T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

519472:BHY08 RS01270
gene id: 519472:BHY08_RS01270
uniprot id: A0A1J0A3S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS04560
gene id: 519472:BHY08_RS04560
uniprot id: A0A1J0A5F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

519472:BHY08 RS04615
gene id: 519472:BHY08_RS04615
uniprot id: A0A1J0A5F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

519472:BHY08 RS07960
gene id: 519472:BHY08_RS07960
uniprot id: A0A1J0A761
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS00085
gene id: 519472:BHY08_RS00085
uniprot id: A0A1J0A370
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS08440
gene id: 519472:BHY08_RS08440
uniprot id: A0A1J0A7E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

519472:BHY08 RS08595
gene id: 519472:BHY08_RS08595
uniprot id: A0A1J0A7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

519472:BHY08 RS03230
gene id: 519472:BHY08_RS03230
uniprot id: A0A1J0A4V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

519472:BHY08 RS06855
gene id: 519472:BHY08_RS06855
uniprot id: A0A1J0A6M2
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS01250
gene id: 519472:BHY08_RS01250
uniprot id: A0A1J0A3R2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS06500
gene id: 519472:BHY08_RS06500
uniprot id: A0A1J0A6F4
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS03655
gene id: 519472:BHY08_RS03655
uniprot id: A0A1J0A527
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

519472:BHY08 RS02085
gene id: 519472:BHY08_RS02085
uniprot id: A0A1J0A497
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

519472:BHY08 RS03855
gene id: 519472:BHY08_RS03855
uniprot id: A0A1J0A534
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

519472:BHY08 RS02260
gene id: 519472:BHY08_RS02260
uniprot id: A0A1J0A4A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS08325
gene id: 519472:BHY08_RS08325
uniprot id: A0A1J0A7A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS03110
gene id: 519472:BHY08_RS03110
uniprot id: A0A1J0A4P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

519472:BHY08 RS01765
gene id: 519472:BHY08_RS01765
uniprot id: A0A1J0A409
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS06255
gene id: 519472:BHY08_RS06255
uniprot id: A0A1J0A6C8
names: Similarity
messages: Belongs to the CvfB family.

519472:BHY08 RS00190
gene id: 519472:BHY08_RS00190
uniprot id: A0A1J0A3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS07670
gene id: 519472:BHY08_RS07670
uniprot id: A0A1J0A702
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

519472:BHY08 RS06075
gene id: 519472:BHY08_RS06075
uniprot id: A0A1J0A699
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Belongs to the RNase PH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

519472:BHY08 RS00140
gene id: 519472:BHY08_RS00140
uniprot id: A0A1J0A399
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

519472:BHY08 RS10480
gene id: 519472:BHY08_RS10480
uniprot id: A0A1J0A897
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS08155
gene id: 519472:BHY08_RS08155
uniprot id: A0A1J0A7A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

519472:BHY08 RS08715
gene id: 519472:BHY08_RS08715
uniprot id: A0A1J0A8K7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

519472:BHY08 RS04605
gene id: 519472:BHY08_RS04605
uniprot id: A0A1J0A5F9
names: Similarity
messages: Belongs to the DprA/Smf family.

519472:BHY08 RS09335
gene id: 519472:BHY08_RS09335
uniprot id: A0A1J0A7W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

519472:BHY08 RS06870
gene id: 519472:BHY08_RS06870
uniprot id: A0A1J0A6N8
names: Subcellular Location Annotation
messages: Cytoplasm

519472:BHY08 RS03630
gene id: 519472:BHY08_RS03630
uniprot id: A0A1J0A4Z8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

519472:BHY08 RS09290
gene id: 519472:BHY08_RS09290
uniprot id: A0A1J0A7S0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

519472:BHY08 RS00955
gene id: 519472:BHY08_RS00955
uniprot id: A0A1J0A3L2
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS08860
gene id: 519472:BHY08_RS08860
uniprot id: A0A1J0A7L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

519472:BHY08 RS06515
gene id: 519472:BHY08_RS06515
uniprot id: A0A1J0A6G9
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

519472:BHY08 RS09520
gene id: 519472:BHY08_RS09520
uniprot id: A0A1J0A7W0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

519472:BHY08 RS03255
gene id: 519472:BHY08_RS03255
uniprot id: A0A1J0A4W5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

519472:BHY08 RS03080
gene id: 519472:BHY08_RS03080
uniprot id: A0A1J0A4M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS10180
gene id: 519472:BHY08_RS10180
uniprot id: A0A1J0A8A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

519472:BHY08 RS05165
gene id: 519472:BHY08_RS05165
uniprot id: A0A1J0A5R0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS04335
gene id: 519472:BHY08_RS04335
uniprot id: A0A1J0A5B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

519472:BHY08 RS04690
gene id: 519472:BHY08_RS04690
uniprot id: A0A1J0A5H8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

519472:BHY08 RS06960
gene id: 519472:BHY08_RS06960
uniprot id: A0A1J0A6M6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

519472:BHY08 RS05755
gene id: 519472:BHY08_RS05755
uniprot id: A0A1J0A613
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

519472:BHY08 RS03370
gene id: 519472:BHY08_RS03370
uniprot id: A0A1J0A4X8
names: Subcellular Location Annotation
messages: Cell membrane

519472:BHY08 RS02910
gene id: 519472:BHY08_RS02910
uniprot id: A0A1J0A4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

519472:BHY08 RS07540
gene id: 519472:BHY08_RS07540
uniprot id: A0A1J0A6X8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519472:BHY08 RS07465
gene id: 519472:BHY08_RS07465
uniprot id: A0A1J0A6Y9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

519472:BHY08 RS10465
gene id: 519472:BHY08_RS10465
uniprot id: A0A1J0A8C3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

519472:BHY08 RS06430
gene id: 519472:BHY08_RS06430
uniprot id: A0A1J0A6D5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS07375
gene id: 519472:BHY08_RS07375
uniprot id: A0A1J0A6U6
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

519472:BHY08 RS06970
gene id: 519472:BHY08_RS06970
uniprot id: A0A1J0A6N3
names: Subcellular Location Annotation
messages: Cytoplasm

519472:BHY08 RS02410
gene id: 519472:BHY08_RS02410
uniprot id: A0A1J0A4B2
names: Similarity
messages: Belongs to the thioredoxin family.

519472:BHY08 RS04595
gene id: 519472:BHY08_RS04595
uniprot id: A0A1J0A5I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

519472:BHY08 RS01320
gene id: 519472:BHY08_RS01320
uniprot id: A0A1J0A3T0
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).

519472:BHY08 RS08660
gene id: 519472:BHY08_RS08660
uniprot id: A0A1J0A7F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

519472:BHY08 RS08615
gene id: 519472:BHY08_RS08615
uniprot id: A0A1J0A7J2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

519472:BHY08 RS06670
gene id: 519472:BHY08_RS06670
uniprot id: A0A1J0A6J9
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

519472:BHY08 RS04545
gene id: 519472:BHY08_RS04545
uniprot id: A0A1J0A5H4
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS00580
gene id: 519472:BHY08_RS00580
uniprot id: A0A1J0A3F6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

519472:BHY08 RS04630
gene id: 519472:BHY08_RS04630
uniprot id: A0A1J0A5I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

519472:BHY08 RS07150
gene id: 519472:BHY08_RS07150
uniprot id: A0A1J0A6Q8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

519472:BHY08 RS03260
gene id: 519472:BHY08_RS03260
uniprot id: A0A1J0A4R8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: Belongs to the CRISPR-associated protein Cas9 family. Subtype II-A subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

519472:BHY08 RS03035
gene id: 519472:BHY08_RS03035
uniprot id: A0A1J0A8D6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

519472:BHY08 RS06310
gene id: 519472:BHY08_RS06310
uniprot id: A0A1J0A6C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS02450
gene id: 519472:BHY08_RS02450
uniprot id: A0A1J0A4B9
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

519472:BHY08 RS07735
gene id: 519472:BHY08_RS07735
uniprot id: A0A1J0A742
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

519472:BHY08 RS08910
gene id: 519472:BHY08_RS08910
uniprot id: A0A1J0A7L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

519472:BHY08 RS04985
gene id: 519472:BHY08_RS04985
uniprot id: A0A1J0A5M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

519472:BHY08 RS10605
gene id: 519472:BHY08_RS10605
uniprot id: A0A1J0A8N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

519472:BHY08 RS08635
gene id: 519472:BHY08_RS08635
uniprot id: A0A1J0A7G5
names: Similarity
messages: Belongs to the ThiD family.

519472:BHY08 RS00730
gene id: 519472:BHY08_RS00730
uniprot id: A0A1J0A3H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

519472:BHY08 RS04340
gene id: 519472:BHY08_RS04340
uniprot id: A0A1J0A5E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

519472:BHY08 RS01015
gene id: 519472:BHY08_RS01015
uniprot id: A0A1J0A3L8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

519472:BHY08 RS01670
gene id: 519472:BHY08_RS01670
uniprot id: A0A1J0A3X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS04275
gene id: 519472:BHY08_RS04275
uniprot id: A0A1J0A5C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

519472:BHY08 RS05350
gene id: 519472:BHY08_RS05350
uniprot id: A0A1J0A5W3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

519472:BHY08 RS02140
gene id: 519472:BHY08_RS02140
uniprot id: A0A1J0A472
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

519472:BHY08 RS03535
gene id: 519472:BHY08_RS03535
uniprot id: A0A1J0A509
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

519472:BHY08 RS05370
gene id: 519472:BHY08_RS05370
uniprot id: A0A1J0A5U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

519472:BHY08 RS04665
gene id: 519472:BHY08_RS04665
uniprot id: A0A1J0A5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

519472:BHY08 RS09010
gene id: 519472:BHY08_RS09010
uniprot id: A0A1J0A7Q5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

519472:BHY08 RS07120
gene id: 519472:BHY08_RS07120
uniprot id: A0A1J0A6S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

519472:BHY08 RS09405
gene id: 519472:BHY08_RS09405
uniprot id: A0A1J0A7U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

519472:BHY08 RS07045
gene id: 519472:BHY08_RS07045
uniprot id: A0A1J0A6Q3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS05515
gene id: 519472:BHY08_RS05515
uniprot id: A0A1J0A5X4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

519472:BHY08 RS03990
gene id: 519472:BHY08_RS03990
uniprot id: A0A1J0A553
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS03270
gene id: 519472:BHY08_RS03270
uniprot id: A0A1J0A4W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

519472:BHY08 RS03615
gene id: 519472:BHY08_RS03615
uniprot id: A0A1J0A4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

519472:BHY08 RS01275
gene id: 519472:BHY08_RS01275
uniprot id: A0A1J0A3R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS05180
gene id: 519472:BHY08_RS05180
uniprot id: A0A1J0A5S7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

519472:BHY08 RS00740
gene id: 519472:BHY08_RS00740
uniprot id: A0A1J0A3H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

519472:BHY08 RS01795
gene id: 519472:BHY08_RS01795
uniprot id: A0A1J0A418
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

519472:BHY08 RS01590
gene id: 519472:BHY08_RS01590
uniprot id: A0A1J0A3Y2
names: Similarity
messages: Belongs to the UPF0758 family.

519472:BHY08 RS02290
gene id: 519472:BHY08_RS02290
uniprot id: A0A1J0A491
names: Similarity
messages: Belongs to the peptidase M20A family.

519472:BHY08 RS10270
gene id: 519472:BHY08_RS10270
uniprot id: A0A1J0A8Q3
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

519472:BHY08 RS03225
gene id: 519472:BHY08_RS03225
uniprot id: A0A1J0A4T6
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

519472:BHY08 RS00400
gene id: 519472:BHY08_RS00400
uniprot id: A0A1J0A3D7
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS03910
gene id: 519472:BHY08_RS03910
uniprot id: A0A1J0A541
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

519472:BHY08 RS01205
gene id: 519472:BHY08_RS01205
uniprot id: A0A1J0A3S4
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

519472:BHY08 RS01000
gene id: 519472:BHY08_RS01000
uniprot id: A0A1J0A3M2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

519472:BHY08 RS02430
gene id: 519472:BHY08_RS02430
uniprot id: A0A1J0A4B8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

519472:BHY08 RS10010
gene id: 519472:BHY08_RS10010
uniprot id: A0A1J0A858
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS01675
gene id: 519472:BHY08_RS01675
uniprot id: A0A1J0A3Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS07595
gene id: 519472:BHY08_RS07595
uniprot id: A0A1J0A710
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

519472:BHY08 RS08690
gene id: 519472:BHY08_RS08690
uniprot id: A0A1J0A7H9
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

519472:BHY08 RS08195
gene id: 519472:BHY08_RS08195
uniprot id: A0A1J0A7A9
names: Similarity
messages: Belongs to the UPF0177 family.

519472:BHY08 RS07480
gene id: 519472:BHY08_RS07480
uniprot id: A0A1J0A6Z1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS08500
gene id: 519472:BHY08_RS08500
uniprot id: A0A1J0A7D8
names: Similarity
messages: Belongs to the peptidase S66 family.

519472:BHY08 RS11170
gene id: 519472:BHY08_RS11170
uniprot id: A0A1J0A7M0
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS00995
gene id: 519472:BHY08_RS00995
uniprot id: A0A1J0A3M0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

519472:BHY08 RS10495
gene id: 519472:BHY08_RS10495
uniprot id: A0A1J0A8B4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

519472:BHY08 RS09360
gene id: 519472:BHY08_RS09360
uniprot id: A0A1J0A7S2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

519472:BHY08 RS09940
gene id: 519472:BHY08_RS09940
uniprot id: A0A1J0A854
names: Similarity
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Homotetramer.

519472:BHY08 RS02930
gene id: 519472:BHY08_RS02930
uniprot id: A0A1J0A4P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS10235
gene id: 519472:BHY08_RS10235
uniprot id: A0A1J0A8A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

519472:BHY08 RS01355
gene id: 519472:BHY08_RS01355
uniprot id: A0A1J0A3T9
names: Similarity
messages: Belongs to the UPF0177 family.

519472:BHY08 RS09880
gene id: 519472:BHY08_RS09880
uniprot id: A0A1J0A835
names: Similarity
messages: Belongs to the peptidase C1 family.

519472:BHY08 RS09545
gene id: 519472:BHY08_RS09545
uniprot id: A0A1J0A7X0
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

519472:BHY08 RS09540
gene id: 519472:BHY08_RS09540
uniprot id: A0A1J0A7V4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

519472:BHY08 RS08365
gene id: 519472:BHY08_RS08365
uniprot id: A0A1J0A7B2
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS01060
gene id: 519472:BHY08_RS01060
uniprot id: A0A1J0A3N4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

519472:BHY08 RS09865
gene id: 519472:BHY08_RS09865
uniprot id: A0A1J0A848
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS03570
gene id: 519472:BHY08_RS03570
uniprot id: A0A1J0A4X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

519472:BHY08 RS01870
gene id: 519472:BHY08_RS01870
uniprot id: A0A1J0A452
names: Similarity
messages: Belongs to the Dps family.

519472:BHY08 RS02330
gene id: 519472:BHY08_RS02330
uniprot id: A0A1J0A4E0
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS08705
gene id: 519472:BHY08_RS08705
uniprot id: A0A1J0A7G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

519472:BHY08 RS05700
gene id: 519472:BHY08_RS05700
uniprot id: A0A1J0A627
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS08385
gene id: 519472:BHY08_RS08385
uniprot id: A0A1J0A7E2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

519472:BHY08 RS05620
gene id: 519472:BHY08_RS05620
uniprot id: A0A1J0A612
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

519472:BHY08 RS09130
gene id: 519472:BHY08_RS09130
uniprot id: A0A1J0A7P1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

519472:BHY08 RS07500
gene id: 519472:BHY08_RS07500
uniprot id: A0A1J0A6X1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

519472:BHY08 RS04205
gene id: 519472:BHY08_RS04205
uniprot id: A0A1J0A583
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS05355
gene id: 519472:BHY08_RS05355
uniprot id: A0A1J0A5V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

519472:BHY08 RS04070
gene id: 519472:BHY08_RS04070
uniprot id: A0A1J0A8G4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

519472:BHY08 RS03280
gene id: 519472:BHY08_RS03280
uniprot id: A0A1J0A4T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS07900
gene id: 519472:BHY08_RS07900
uniprot id: A0A1J0A764
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS05365
gene id: 519472:BHY08_RS05365
uniprot id: A0A1J0A5W2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

519472:BHY08 RS02435
gene id: 519472:BHY08_RS02435
uniprot id: A0A1J0A4A4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

519472:BHY08 RS07310
gene id: 519472:BHY08_RS07310
uniprot id: A0A1J0A6V7
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS06580
gene id: 519472:BHY08_RS06580
uniprot id: A0A1J0A6I7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

519472:BHY08 RS06240
gene id: 519472:BHY08_RS06240
uniprot id: A0A1J0A6C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

519472:BHY08 RS05760
gene id: 519472:BHY08_RS05760
uniprot id: A0A1J0A637
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

519472:BHY08 RS04635
gene id: 519472:BHY08_RS04635
uniprot id: A0A1J0A5J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

519472:BHY08 RS09275
gene id: 519472:BHY08_RS09275
uniprot id: A0A1J0A7R3
names: Similarity
messages: Belongs to the UPF0758 family.

519472:BHY08 RS06070
gene id: 519472:BHY08_RS06070
uniprot id: A0A1J0A671
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

519472:BHY08 RS05050
gene id: 519472:BHY08_RS05050
uniprot id: A0A1J0A5P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS01720
gene id: 519472:BHY08_RS01720
uniprot id: A0A1J0A403
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

519472:BHY08 RS04600
gene id: 519472:BHY08_RS04600
uniprot id: A0A1J0A5G5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

519472:BHY08 RS07445
gene id: 519472:BHY08_RS07445
uniprot id: A0A1J0A6X2
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

519472:BHY08 RS05060
gene id: 519472:BHY08_RS05060
uniprot id: A0A1J0A5R3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

519472:BHY08 RS01095
gene id: 519472:BHY08_RS01095
uniprot id: A0A1J0A3N3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

519472:BHY08 RS02235
gene id: 519472:BHY08_RS02235
uniprot id: A0A1J0A4C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

519472:BHY08 RS06220
gene id: 519472:BHY08_RS06220
uniprot id: A0A1J0A692
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

519472:BHY08 RS02710
gene id: 519472:BHY08_RS02710
uniprot id: A0A1J0A4J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

519472:BHY08 RS03575
gene id: 519472:BHY08_RS03575
uniprot id: A0A1J0A4Z6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

519472:BHY08 RS04995
gene id: 519472:BHY08_RS04995
uniprot id: A0A1J0A5P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

519472:BHY08 RS08025
gene id: 519472:BHY08_RS08025
uniprot id: A0A1J0A768
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

519472:BHY08 RS02440
gene id: 519472:BHY08_RS02440
uniprot id: A0A1J0A4C8
names: Similarity
messages: Belongs to the CinA family.

519472:BHY08 RS07790
gene id: 519472:BHY08_RS07790
uniprot id: A0A1J0A748
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

519472:BHY08 RS01985
gene id: 519472:BHY08_RS01985
uniprot id: A0A1J0A437
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

519472:BHY08 RS07870
gene id: 519472:BHY08_RS07870
uniprot id: A0A1J0A754
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

519472:BHY08 RS07895
gene id: 519472:BHY08_RS07895
uniprot id: A0A1J0A728
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

519472:BHY08 RS03740
gene id: 519472:BHY08_RS03740
uniprot id: A0A1J0A543
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

519472:BHY08 RS00065
gene id: 519472:BHY08_RS00065
uniprot id: A0A1J0A383
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

519472:BHY08 RS07385
gene id: 519472:BHY08_RS07385
uniprot id: A0A1J0A6V4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS00920
gene id: 519472:BHY08_RS00920
uniprot id: A0A1J0A3L1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

519472:BHY08 RS06765
gene id: 519472:BHY08_RS06765
uniprot id: A0A1J0A6I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

519472:BHY08 RS07495
gene id: 519472:BHY08_RS07495
uniprot id: A0A1J0A6W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

519472:BHY08 RS08920
gene id: 519472:BHY08_RS08920
uniprot id: A0A1J0A7M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

519472:BHY08 RS05330
gene id: 519472:BHY08_RS05330
uniprot id: A0A1J0A5T7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

519472:BHY08 RS03460
gene id: 519472:BHY08_RS03460
uniprot id: A0A1J0A4U9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

519472:BHY08 RS03865
gene id: 519472:BHY08_RS03865
uniprot id: A0A1J0A556
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

519472:BHY08 RS07280
gene id: 519472:BHY08_RS07280
uniprot id: A0A1J0A6T2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

519472:BHY08 RS05405
gene id: 519472:BHY08_RS05405
uniprot id: A0A1J0A5X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS08370
gene id: 519472:BHY08_RS08370
uniprot id: A0A1J0A7B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

519472:BHY08 RS02335
gene id: 519472:BHY08_RS02335
uniprot id: A0A1J0A499
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.

519472:BHY08 RS06145
gene id: 519472:BHY08_RS06145
uniprot id: A0A1J0A681
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

519472:BHY08 RS01075
gene id: 519472:BHY08_RS01075
uniprot id: A0A1J0A3N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

519472:BHY08 RS03915
gene id: 519472:BHY08_RS03915
uniprot id: A0A1J0A566
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS06775
gene id: 519472:BHY08_RS06775
uniprot id: A0A1J0A6J2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

519472:BHY08 RS01370
gene id: 519472:BHY08_RS01370
uniprot id: A0A1J0A3U0
names: Subcellular Location Annotation
messages: Cell membrane

519472:BHY08 RS01915
gene id: 519472:BHY08_RS01915
uniprot id: A0A1J0A461
names: Similarity
messages: Belongs to the isochorismate synthase family.

519472:BHY08 RS06440
gene id: 519472:BHY08_RS06440
uniprot id: A0A1J0A6F9
names: Similarity
messages: Belongs to the carbamate kinase family.

519472:BHY08 RS01310
gene id: 519472:BHY08_RS01310
uniprot id: A0A1J0A3T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family. IolA subfamily.
messages: Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
messages: Homotetramer.

519472:BHY08 RS02285
gene id: 519472:BHY08_RS02285
uniprot id: A0A1J0A4D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

519472:BHY08 RS05555
gene id: 519472:BHY08_RS05555
uniprot id: A0A1J0A5X8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

519472:BHY08 RS05175
gene id: 519472:BHY08_RS05175
uniprot id: A0A1J0A5Q7
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

519472:BHY08 RS10090
gene id: 519472:BHY08_RS10090
uniprot id: A0A1J0A874
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

519472:BHY08 RS07010
gene id: 519472:BHY08_RS07010
uniprot id: A0A1J0A6N0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

519472:BHY08 RS08265
gene id: 519472:BHY08_RS08265
uniprot id: A0A1J0A7A7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

519472:BHY08 RS00615
gene id: 519472:BHY08_RS00615
uniprot id: A0A1J0A3E9
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS02270
gene id: 519472:BHY08_RS02270
uniprot id: A0A1J0A4B5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

519472:BHY08 RS02100
gene id: 519472:BHY08_RS02100
uniprot id: A0A1J0A455
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

519472:BHY08 RS04790
gene id: 519472:BHY08_RS04790
uniprot id: A0A1J0A5I8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

519472:BHY08 RS00055
gene id: 519472:BHY08_RS00055
uniprot id: A0A1J0A380
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

519472:BHY08 RS00010
gene id: 519472:BHY08_RS00010
uniprot id: A0A1J0A371
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

519472:BHY08 RS04490
gene id: 519472:BHY08_RS04490
uniprot id: A0A1J0A5G1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

519472:BHY08 RS06585
gene id: 519472:BHY08_RS06585
uniprot id: A0A1J0A6I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

519472:BHY08 RS04520
gene id: 519472:BHY08_RS04520
uniprot id: A0A1J0A5E3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

519472:BHY08 RS02545
gene id: 519472:BHY08_RS02545
uniprot id: A0A1J0A4E1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

519472:BHY08 RS10095
gene id: 519472:BHY08_RS10095
uniprot id: A0A1J0A881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS03305
gene id: 519472:BHY08_RS03305
uniprot id: A0A1J0A4S6
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

519472:BHY08 RS02490
gene id: 519472:BHY08_RS02490
uniprot id: A0A1J0A4C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

519472:BHY08 RS05055
gene id: 519472:BHY08_RS05055
uniprot id: A0A1J0A5Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS00915
gene id: 519472:BHY08_RS00915
uniprot id: A0A1J0A3K6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519472:BHY08 RS07440
gene id: 519472:BHY08_RS07440
uniprot id: A0A1J0A6Y4
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS02820
gene id: 519472:BHY08_RS02820
uniprot id: A0A1J0A4H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS02840
gene id: 519472:BHY08_RS02840
uniprot id: A0A1J0A4L7
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS10215
gene id: 519472:BHY08_RS10215
uniprot id: A0A1J0A880
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

519472:BHY08 RS10980
gene id: 519472:BHY08_RS10980
uniprot id: A0A1J0A6E3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

519472:BHY08 RS00165
gene id: 519472:BHY08_RS00165
uniprot id: A0A1J0A8C2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

519472:BHY08 RS00030
gene id: 519472:BHY08_RS00030
uniprot id: A0A1J0A374
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

519472:BHY08 RS04485
gene id: 519472:BHY08_RS04485
uniprot id: A0A1J0A5D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

519472:BHY08 RS04495
gene id: 519472:BHY08_RS04495
uniprot id: A0A1J0A5E7
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

519472:BHY08 RS02155
gene id: 519472:BHY08_RS02155
uniprot id: A0A1J0A463
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

519472:BHY08 RS07680
gene id: 519472:BHY08_RS07680
uniprot id: A0A1J0A705
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

519472:BHY08 RS06115
gene id: 519472:BHY08_RS06115
uniprot id: A0A1J0A697
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS06540
gene id: 519472:BHY08_RS06540
uniprot id: A0A1J0A6E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

519472:BHY08 RS08205
gene id: 519472:BHY08_RS08205
uniprot id: A0A1J0A7B0
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

519472:BHY08 RS04835
gene id: 519472:BHY08_RS04835
uniprot id: A0A1J0A5J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

519472:BHY08 RS09030
gene id: 519472:BHY08_RS09030
uniprot id: A0A1J0A7N4
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

519472:BHY08 RS07505
gene id: 519472:BHY08_RS07505
uniprot id: A0A1J0A6Z5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

519472:BHY08 RS06480
gene id: 519472:BHY08_RS06480
uniprot id: A0A1J0A6H1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Homotetramer.

519472:BHY08 RS07535
gene id: 519472:BHY08_RS07535
uniprot id: A0A1J0A6X4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

519472:BHY08 RS02305
gene id: 519472:BHY08_RS02305
uniprot id: A0A1J0A4A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519472:BHY08 RS00610
gene id: 519472:BHY08_RS00610
uniprot id: A0A1J0A3F1
names: Subcellular Location Annotation
messages: Membrane

519472:BHY08 RS02230
gene id: 519472:BHY08_RS02230
uniprot id: A0A1J0A4A1
names: Subcellular Location Annotation
messages: Cell membrane

519472:BHY08 RS04345
gene id: 519472:BHY08_RS04345
uniprot id: A0A1J0A5B7
names: Similarity
messages: Belongs to the acylphosphatase family.

519472:BHY08 RS07660
gene id: 519472:BHY08_RS07660
uniprot id: A0A1J0A716
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

519472:BHY08 RS07260
gene id: 519472:BHY08_RS07260
uniprot id: A0A1J0A8K0
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

519472:BHY08 RS02255
gene id: 519472:BHY08_RS02255
uniprot id: A0A1J0A474
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519472:BHY08 RS07865
gene id: 519472:BHY08_RS07865
uniprot id: A0A1J0A753
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

519472:BHY08 RS04720
gene id: 519472:BHY08_RS04720
uniprot id: A0A1J0A5J2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.