519442:HUTA RS06785
gene id: 519442:HUTA_RS06785
uniprot id: C7NNP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS11265
gene id: 519442:HUTA_RS11265
uniprot id: C7NV56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

519442:HUTA RS06825
gene id: 519442:HUTA_RS06825
uniprot id: C7NNP9
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

519442:HUTA RS02100
gene id: 519442:HUTA_RS02100
uniprot id: C7NS06
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

519442:HUTA RS03445
gene id: 519442:HUTA_RS03445
uniprot id: C7NTQ1
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

519442:HUTA RS02205
gene id: 519442:HUTA_RS02205
uniprot id: C7NS27
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

519442:HUTA RS10885
gene id: 519442:HUTA_RS10885
uniprot id: C7NUN6
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS05870
gene id: 519442:HUTA_RS05870
uniprot id: C7NMR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

519442:HUTA RS08150
gene id: 519442:HUTA_RS08150
uniprot id: C7NQT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

519442:HUTA RS02725
gene id: 519442:HUTA_RS02725
uniprot id: C7NST0
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

519442:HUTA RS07320
gene id: 519442:HUTA_RS07320
uniprot id: C7NP88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS07325
gene id: 519442:HUTA_RS07325
uniprot id: C7NP89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS13845
gene id: 519442:HUTA_RS13845
uniprot id: C7NQH3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS00405
gene id: 519442:HUTA_RS00405
uniprot id: C7NNY1
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

519442:HUTA RS10400
gene id: 519442:HUTA_RS10400
uniprot id: C7NU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

519442:HUTA RS01790
gene id: 519442:HUTA_RS01790
uniprot id: C7NRB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

519442:HUTA RS10425
gene id: 519442:HUTA_RS10425
uniprot id: C7NU52
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

519442:HUTA RS11235
gene id: 519442:HUTA_RS11235
uniprot id: C7NV50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

519442:HUTA RS00035
gene id: 519442:HUTA_RS00035
uniprot id: C7NNG9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

519442:HUTA RS12375
gene id: 519442:HUTA_RS12375
uniprot id: C7NMY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

519442:HUTA RS07110
gene id: 519442:HUTA_RS07110
uniprot id: C7NNV6
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.

519442:HUTA RS06900
gene id: 519442:HUTA_RS06900
uniprot id: C7NNR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

519442:HUTA RS11290
gene id: 519442:HUTA_RS11290
uniprot id: C7NV61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

519442:HUTA RS13865
gene id: 519442:HUTA_RS13865
uniprot id: C7NQH6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

519442:HUTA RS03990
gene id: 519442:HUTA_RS03990
uniprot id: C7NUA2
names: Similarity
messages: Belongs to the isochorismate synthase family.

519442:HUTA RS09430
gene id: 519442:HUTA_RS09430
uniprot id: C7NT21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

519442:HUTA RS11450
gene id: 519442:HUTA_RS11450
uniprot id: C7NVI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

519442:HUTA RS11260
gene id: 519442:HUTA_RS11260
uniprot id: C7NV55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

519442:HUTA RS00985
gene id: 519442:HUTA_RS00985
uniprot id: C7NPU4
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

519442:HUTA RS10410
gene id: 519442:HUTA_RS10410
uniprot id: C7NU48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

519442:HUTA RS07990
gene id: 519442:HUTA_RS07990
uniprot id: C7NQ68
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

519442:HUTA RS03155
gene id: 519442:HUTA_RS03155
uniprot id: C7NTA8
names: Function
names: Similarity
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

519442:HUTA RS03255
gene id: 519442:HUTA_RS03255
uniprot id: C7NTC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

519442:HUTA RS10355
gene id: 519442:HUTA_RS10355
uniprot id: C7NU37
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS11245
gene id: 519442:HUTA_RS11245
uniprot id: C7NV52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

519442:HUTA RS00770
gene id: 519442:HUTA_RS00770
uniprot id: C7NP56
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

519442:HUTA RS12855
gene id: 519442:HUTA_RS12855
uniprot id: C7NPM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

519442:HUTA RS01405
gene id: 519442:HUTA_RS01405
uniprot id: C7NQL9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

519442:HUTA RS01520
gene id: 519442:HUTA_RS01520
uniprot id: C7NQP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS05915
gene id: 519442:HUTA_RS05915
uniprot id: C7NMS6
names: Function
messages: Part of a potassium transport system.

519442:HUTA RS11445
gene id: 519442:HUTA_RS11445
uniprot id: C7NVI1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

519442:HUTA RS08830
gene id: 519442:HUTA_RS08830
uniprot id: C7NRP2
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS07085
gene id: 519442:HUTA_RS07085
uniprot id: C7NNV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

519442:HUTA RS07710
gene id: 519442:HUTA_RS07710
uniprot id: C7NQ12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

519442:HUTA RS01500
gene id: 519442:HUTA_RS01500
uniprot id: C7NQN8
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

519442:HUTA RS07840
gene id: 519442:HUTA_RS07840
uniprot id: C7NQ38
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

519442:HUTA RS01345
gene id: 519442:HUTA_RS01345
uniprot id: C7NQK5
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

519442:HUTA RS08835
gene id: 519442:HUTA_RS08835
uniprot id: C7NRP3
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS00370
gene id: 519442:HUTA_RS00370
uniprot id: C7NNN7
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS15835
gene id: 519442:HUTA_RS15835
uniprot id: C7NUT1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

519442:HUTA RS10025
gene id: 519442:HUTA_RS10025
uniprot id: C7NTM7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

519442:HUTA RS00085
gene id: 519442:HUTA_RS00085
uniprot id: C7NNH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

519442:HUTA RS11305
gene id: 519442:HUTA_RS11305
uniprot id: C7NV64
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

519442:HUTA RS08910
gene id: 519442:HUTA_RS08910
uniprot id: C7NSA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

519442:HUTA RS06775
gene id: 519442:HUTA_RS06775
uniprot id: C7NNN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

519442:HUTA RS04045
gene id: 519442:HUTA_RS04045
uniprot id: C7NUB4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS06295
gene id: 519442:HUTA_RS06295
uniprot id: C7NN66
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

519442:HUTA RS06965
gene id: 519442:HUTA_RS06965
uniprot id: C7NNS7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

519442:HUTA RS12590
gene id: 519442:HUTA_RS12590
uniprot id: C7NPH3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

519442:HUTA RS10385
gene id: 519442:HUTA_RS10385
uniprot id: C7NU43
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

519442:HUTA RS03165
gene id: 519442:HUTA_RS03165
uniprot id: C7NTB0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

519442:HUTA RS06065
gene id: 519442:HUTA_RS06065
uniprot id: C7NN19
names: Similarity
messages: Belongs to the aspartokinase family.

519442:HUTA RS04120
gene id: 519442:HUTA_RS04120
uniprot id: C7NUC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

519442:HUTA RS02135
gene id: 519442:HUTA_RS02135
uniprot id: C7NS13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

519442:HUTA RS14100
gene id: 519442:HUTA_RS14100
uniprot id: C7NRT5
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

519442:HUTA RS11300
gene id: 519442:HUTA_RS11300
uniprot id: C7NV63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

519442:HUTA RS13030
gene id: 519442:HUTA_RS13030
uniprot id: C7NQ93
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

519442:HUTA RS06250
gene id: 519442:HUTA_RS06250
uniprot id: C7NN57
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS04495
gene id: 519442:HUTA_RS04495
uniprot id: C7NUT8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

519442:HUTA RS01995
gene id: 519442:HUTA_RS01995
uniprot id: C7NRF5
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.

519442:HUTA RS14480
gene id: 519442:HUTA_RS14480
uniprot id: C7NSK1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

519442:HUTA RS05345
gene id: 519442:HUTA_RS05345
uniprot id: C7NM66
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS04445
gene id: 519442:HUTA_RS04445
uniprot id: C7NUS7
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

519442:HUTA RS04650
gene id: 519442:HUTA_RS04650
uniprot id: C7NUW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

519442:HUTA RS03685
gene id: 519442:HUTA_RS03685
uniprot id: C7NTU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

519442:HUTA RS01435
gene id: 519442:HUTA_RS01435
uniprot id: C7NQM5
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS03835
gene id: 519442:HUTA_RS03835
uniprot id: C7NTX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

519442:HUTA RS07690
gene id: 519442:HUTA_RS07690
uniprot id: C7NQ08
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS01080
gene id: 519442:HUTA_RS01080
uniprot id: C7NPW3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

519442:HUTA RS01125
gene id: 519442:HUTA_RS01125
uniprot id: C7NPX2
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

519442:HUTA RS03295
gene id: 519442:HUTA_RS03295
uniprot id: C7NTD7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

519442:HUTA RS08985
gene id: 519442:HUTA_RS08985
uniprot id: C7NSC1
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS10855
gene id: 519442:HUTA_RS10855
uniprot id: C7NUN0
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS10280
gene id: 519442:HUTA_RS10280
uniprot id: C7NU21
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

519442:HUTA RS02570
gene id: 519442:HUTA_RS02570
uniprot id: C7NSA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

519442:HUTA RS03360
gene id: 519442:HUTA_RS03360
uniprot id: C7NTF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

519442:HUTA RS01310
gene id: 519442:HUTA_RS01310
uniprot id: C7NQJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

519442:HUTA RS11410
gene id: 519442:HUTA_RS11410
uniprot id: C7NVH5
names: Similarity
messages: Belongs to the HupF/HypC family.

519442:HUTA RS12260
gene id: 519442:HUTA_RS12260
uniprot id: C7NMW4
names: Similarity
messages: Belongs to the UPF0284 family.

519442:HUTA RS06485
gene id: 519442:HUTA_RS06485
uniprot id: C7NNA6
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

519442:HUTA RS12290
gene id: 519442:HUTA_RS12290
uniprot id: C7NMX0
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS05115
gene id: 519442:HUTA_RS05115
uniprot id: C7NVE3
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS13505
gene id: 519442:HUTA_RS13505
uniprot id: C7NR04
names: Similarity
messages: Belongs to the archease family.

519442:HUTA RS01550
gene id: 519442:HUTA_RS01550
uniprot id: C7NQP8
names: Function
names: Similarity
messages: Activates transcription of bacteriorhodopsin (bop) and phytoene synthase (crtB1). May interact with DNA or RNA via the zinc finger motif (By similarity).
messages: Belongs to the Brz family.

519442:HUTA RS02790
gene id: 519442:HUTA_RS02790
uniprot id: C7NSU3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS11985
gene id: 519442:HUTA_RS11985
uniprot id: C7NMH0
names: Similarity
messages: Belongs to the xylose isomerase family.

519442:HUTA RS03185
gene id: 519442:HUTA_RS03185
uniprot id: C7NTB5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

519442:HUTA RS09870
gene id: 519442:HUTA_RS09870
uniprot id: C7NTJ6
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).

519442:HUTA RS02740
gene id: 519442:HUTA_RS02740
uniprot id: C7NST3
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

519442:HUTA RS09525
gene id: 519442:HUTA_RS09525
uniprot id: C7NT41
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

519442:HUTA RS11230
gene id: 519442:HUTA_RS11230
uniprot id: C7NV49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

519442:HUTA RS08045
gene id: 519442:HUTA_RS08045
uniprot id: C7NQS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

519442:HUTA RS13210
gene id: 519442:HUTA_RS13210
uniprot id: C7NQD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

519442:HUTA RS06190
gene id: 519442:HUTA_RS06190
uniprot id: C7NN46
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

519442:HUTA RS14075
gene id: 519442:HUTA_RS14075
uniprot id: C7NRT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

519442:HUTA RS13785
gene id: 519442:HUTA_RS13785
uniprot id: C7NR65
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS10915
gene id: 519442:HUTA_RS10915
uniprot id: C7NUP2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

519442:HUTA RS05690
gene id: 519442:HUTA_RS05690
uniprot id: C7NMM9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS07280
gene id: 519442:HUTA_RS07280
uniprot id: C7NP80
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

519442:HUTA RS12570
gene id: 519442:HUTA_RS12570
uniprot id: C7NPG9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.

519442:HUTA RS09685
gene id: 519442:HUTA_RS09685
uniprot id: C7NT72
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

519442:HUTA RS10720
gene id: 519442:HUTA_RS10720
uniprot id: C7NUK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

519442:HUTA RS04620
gene id: 519442:HUTA_RS04620
uniprot id: C7NUW3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

519442:HUTA RS03400
gene id: 519442:HUTA_RS03400
uniprot id: C7NTP1
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS12355
gene id: 519442:HUTA_RS12355
uniprot id: C7NMY4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

519442:HUTA RS00320
gene id: 519442:HUTA_RS00320
uniprot id: C7NNM5
names: Subcellular Location Annotation
messages: Cytoplasm

519442:HUTA RS03655
gene id: 519442:HUTA_RS03655
uniprot id: C7NTU2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS03065
gene id: 519442:HUTA_RS03065
uniprot id: C7NT88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

519442:HUTA RS06020
gene id: 519442:HUTA_RS06020
uniprot id: C7NN10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519442:HUTA RS09720
gene id: 519442:HUTA_RS09720
uniprot id: C7NTG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

519442:HUTA RS10215
gene id: 519442:HUTA_RS10215
uniprot id: C7NU07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

519442:HUTA RS05055
gene id: 519442:HUTA_RS05055
uniprot id: C7NVD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

519442:HUTA RS11355
gene id: 519442:HUTA_RS11355
uniprot id: C7NVG3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

519442:HUTA RS07000
gene id: 519442:HUTA_RS07000
uniprot id: C7NNT4
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS07130
gene id: 519442:HUTA_RS07130
uniprot id: C7NNW1
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS12295
gene id: 519442:HUTA_RS12295
uniprot id: C7NMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

519442:HUTA RS02055
gene id: 519442:HUTA_RS02055
uniprot id: C7NRG7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

519442:HUTA RS14540
gene id: 519442:HUTA_RS14540
uniprot id: C7NSL3
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS07025
gene id: 519442:HUTA_RS07025
uniprot id: C7NNT9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

519442:HUTA RS06260
gene id: 519442:HUTA_RS06260
uniprot id: C7NN59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.
messages: Tetramer of two components I and two components II.

519442:HUTA RS12195
gene id: 519442:HUTA_RS12195
uniprot id: C7NMV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS03380
gene id: 519442:HUTA_RS03380
uniprot id: C7NTF4
names: Subcellular Location Annotation
messages: Cytoplasm

519442:HUTA RS11465
gene id: 519442:HUTA_RS11465
uniprot id: C7NVI5
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

519442:HUTA RS11135
gene id: 519442:HUTA_RS11135
uniprot id: C7NV31
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

519442:HUTA RS09640
gene id: 519442:HUTA_RS09640
uniprot id: C7NT63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

519442:HUTA RS00875
gene id: 519442:HUTA_RS00875
uniprot id: C7NPS2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

519442:HUTA RS10170
gene id: 519442:HUTA_RS10170
uniprot id: C7NTZ8
names: Subcellular Location Annotation
messages: Cytoplasm

519442:HUTA RS13340
gene id: 519442:HUTA_RS13340
uniprot id: C7NQF8
names: Similarity
messages: Belongs to the UPF0175 family.

519442:HUTA RS01855
gene id: 519442:HUTA_RS01855
uniprot id: C7NRD1
names: Similarity
messages: Belongs to the DtxR/MntR family.

519442:HUTA RS10000
gene id: 519442:HUTA_RS10000
uniprot id: C7NTM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

519442:HUTA RS04205
gene id: 519442:HUTA_RS04205
uniprot id: C7NUE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

519442:HUTA RS13105
gene id: 519442:HUTA_RS13105
uniprot id: C7NQA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

519442:HUTA RS06155
gene id: 519442:HUTA_RS06155
uniprot id: C7NN38
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS07365
gene id: 519442:HUTA_RS07365
uniprot id: C7NP98
names: Similarity
messages: Belongs to the HAM1 NTPase family.

519442:HUTA RS10650
gene id: 519442:HUTA_RS10650
uniprot id: C7NUI8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

519442:HUTA RS01280
gene id: 519442:HUTA_RS01280
uniprot id: C7NQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

519442:HUTA RS02220
gene id: 519442:HUTA_RS02220
uniprot id: C7NS30
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

519442:HUTA RS03305
gene id: 519442:HUTA_RS03305
uniprot id: C7NTD9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

519442:HUTA RS12535
gene id: 519442:HUTA_RS12535
uniprot id: C7NPG2
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS03730
gene id: 519442:HUTA_RS03730
uniprot id: C7NTV8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS05625
gene id: 519442:HUTA_RS05625
uniprot id: C7NMC0
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

519442:HUTA RS12150
gene id: 519442:HUTA_RS12150
uniprot id: C7NMK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

519442:HUTA RS10275
gene id: 519442:HUTA_RS10275
uniprot id: C7NU20
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

519442:HUTA RS08745
gene id: 519442:HUTA_RS08745
uniprot id: C7NRM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

519442:HUTA RS05140
gene id: 519442:HUTA_RS05140
uniprot id: C7NVE8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

519442:HUTA RS09695
gene id: 519442:HUTA_RS09695
uniprot id: C7NTF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

519442:HUTA RS02875
gene id: 519442:HUTA_RS02875
uniprot id: C7NSW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

519442:HUTA RS01320
gene id: 519442:HUTA_RS01320
uniprot id: C7NQK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

519442:HUTA RS13660
gene id: 519442:HUTA_RS13660
uniprot id: C7NR36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

519442:HUTA RS05785
gene id: 519442:HUTA_RS05785
uniprot id: C7NMP8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

519442:HUTA RS00495
gene id: 519442:HUTA_RS00495
uniprot id: C7NP00
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

519442:HUTA RS03995
gene id: 519442:HUTA_RS03995
uniprot id: C7NUA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

519442:HUTA RS08510
gene id: 519442:HUTA_RS08510
uniprot id: C7NRI1
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS07560
gene id: 519442:HUTA_RS07560
uniprot id: C7NPD9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

519442:HUTA RS11760
gene id: 519442:HUTA_RS11760
uniprot id: C7NMC8
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

519442:HUTA RS00995
gene id: 519442:HUTA_RS00995
uniprot id: C7NPU6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

519442:HUTA RS12415
gene id: 519442:HUTA_RS12415
uniprot id: C7NMZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

519442:HUTA RS06960
gene id: 519442:HUTA_RS06960
uniprot id: C7NNS6
names: Subcellular Location Annotation
messages: Cytoplasm

519442:HUTA RS12160
gene id: 519442:HUTA_RS12160
uniprot id: C7NMK3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS13110
gene id: 519442:HUTA_RS13110
uniprot id: C7NQA9
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

519442:HUTA RS01455
gene id: 519442:HUTA_RS01455
uniprot id: C7NQM9
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

519442:HUTA RS12665
gene id: 519442:HUTA_RS12665
uniprot id: C7NPI7
names: Similarity
messages: Belongs to the arginase family.

519442:HUTA RS06545
gene id: 519442:HUTA_RS06545
uniprot id: C7NNB8
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS01440
gene id: 519442:HUTA_RS01440
uniprot id: C7NQM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

519442:HUTA RS07335
gene id: 519442:HUTA_RS07335
uniprot id: C7NP92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

519442:HUTA RS00280
gene id: 519442:HUTA_RS00280
uniprot id: C7NNL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

519442:HUTA RS04800
gene id: 519442:HUTA_RS04800
uniprot id: C7NV78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

519442:HUTA RS09395
gene id: 519442:HUTA_RS09395
uniprot id: C7NT15
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

519442:HUTA RS04540
gene id: 519442:HUTA_RS04540
uniprot id: C7NUU7
names: Similarity
messages: Belongs to the HMBS family.

519442:HUTA RS01425
gene id: 519442:HUTA_RS01425
uniprot id: C7NQM3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

519442:HUTA RS10980
gene id: 519442:HUTA_RS10980
uniprot id: C7NV00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS14345
gene id: 519442:HUTA_RS14345
uniprot id: C7NRX5
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

519442:HUTA RS01410
gene id: 519442:HUTA_RS01410
uniprot id: C7NQM0
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

519442:HUTA RS13670
gene id: 519442:HUTA_RS13670
uniprot id: C7NR38
names: Similarity
messages: Belongs to the eIF-2-alpha family.

519442:HUTA RS11085
gene id: 519442:HUTA_RS11085
uniprot id: C7NV20
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

519442:HUTA RS11680
gene id: 519442:HUTA_RS11680
uniprot id: C7NVM8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

519442:HUTA RS03265
gene id: 519442:HUTA_RS03265
uniprot id: C7NTD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

519442:HUTA RS13140
gene id: 519442:HUTA_RS13140
uniprot id: C7NQB5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

519442:HUTA RS13190
gene id: 519442:HUTA_RS13190
uniprot id: C7NQC6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

519442:HUTA RS08750
gene id: 519442:HUTA_RS08750
uniprot id: C7NRM9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

519442:HUTA RS14385
gene id: 519442:HUTA_RS14385
uniprot id: C7NSI1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS00410
gene id: 519442:HUTA_RS00410
uniprot id: C7NNY2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

519442:HUTA RS01225
gene id: 519442:HUTA_RS01225
uniprot id: C7NPZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

519442:HUTA RS04365
gene id: 519442:HUTA_RS04365
uniprot id: C7NUR1
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS11220
gene id: 519442:HUTA_RS11220
uniprot id: C7NV47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

519442:HUTA RS10730
gene id: 519442:HUTA_RS10730
uniprot id: C7NUK4
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS02165
gene id: 519442:HUTA_RS02165
uniprot id: C7NS19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

519442:HUTA RS03455
gene id: 519442:HUTA_RS03455
uniprot id: C7NTQ3
names: Similarity
messages: Belongs to the complex I subunit 3 family.

519442:HUTA RS00265
gene id: 519442:HUTA_RS00265
uniprot id: C7NNL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

519442:HUTA RS01590
gene id: 519442:HUTA_RS01590
uniprot id: C7NQQ6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

519442:HUTA RS12350
gene id: 519442:HUTA_RS12350
uniprot id: C7NMY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

519442:HUTA RS04535
gene id: 519442:HUTA_RS04535
uniprot id: C7NUU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

519442:HUTA RS13100
gene id: 519442:HUTA_RS13100
uniprot id: C7NQA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

519442:HUTA RS09165
gene id: 519442:HUTA_RS09165
uniprot id: C7NSF7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS00930
gene id: 519442:HUTA_RS00930
uniprot id: C7NPT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

519442:HUTA RS08145
gene id: 519442:HUTA_RS08145
uniprot id: C7NQT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homodimer.

519442:HUTA RS03390
gene id: 519442:HUTA_RS03390
uniprot id: C7NTF6
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS11295
gene id: 519442:HUTA_RS11295
uniprot id: C7NV62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

519442:HUTA RS03680
gene id: 519442:HUTA_RS03680
uniprot id: C7NTU7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

519442:HUTA RS04590
gene id: 519442:HUTA_RS04590
uniprot id: C7NUV7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

519442:HUTA RS06715
gene id: 519442:HUTA_RS06715
uniprot id: C7NNF1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS09575
gene id: 519442:HUTA_RS09575
uniprot id: C7NT50
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

519442:HUTA RS12025
gene id: 519442:HUTA_RS12025
uniprot id: C7NMH8
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS14355
gene id: 519442:HUTA_RS14355
uniprot id: C7NRX7
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

519442:HUTA RS03520
gene id: 519442:HUTA_RS03520
uniprot id: C7NTR6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

519442:HUTA RS01375
gene id: 519442:HUTA_RS01375
uniprot id: C7NQL2
names: Similarity
messages: Belongs to the glutaredoxin family.

519442:HUTA RS01935
gene id: 519442:HUTA_RS01935
uniprot id: C7NRE5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS11675
gene id: 519442:HUTA_RS11675
uniprot id: C7NVM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

519442:HUTA RS08665
gene id: 519442:HUTA_RS08665
uniprot id: C7NRL3
names: Similarity
messages: Belongs to the RutC family.

519442:HUTA RS12385
gene id: 519442:HUTA_RS12385
uniprot id: C7NMY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

519442:HUTA RS06335
gene id: 519442:HUTA_RS06335
uniprot id: C7NN76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

519442:HUTA RS07745
gene id: 519442:HUTA_RS07745
uniprot id: C7NQ19
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS01775
gene id: 519442:HUTA_RS01775
uniprot id: C7NRB5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

519442:HUTA RS03005
gene id: 519442:HUTA_RS03005
uniprot id: C7NSY6
names: Similarity
messages: Belongs to the glutamate synthase family.

519442:HUTA RS02675
gene id: 519442:HUTA_RS02675
uniprot id: C7NSR9
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

519442:HUTA RS07190
gene id: 519442:HUTA_RS07190
uniprot id: C7NNX3
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS04845
gene id: 519442:HUTA_RS04845
uniprot id: C7NV88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the halobacterial S-layer protein family.
messages: Cell membrane
messages: Membrane
messages: S-layer

519442:HUTA RS09570
gene id: 519442:HUTA_RS09570
uniprot id: C7NT49
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

519442:HUTA RS05525
gene id: 519442:HUTA_RS05525
uniprot id: C7NMA0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

519442:HUTA RS14425
gene id: 519442:HUTA_RS14425
uniprot id: C7NSJ0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

519442:HUTA RS12915
gene id: 519442:HUTA_RS12915
uniprot id: C7NML0
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS04930
gene id: 519442:HUTA_RS04930
uniprot id: C7NVA5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

519442:HUTA RS10350
gene id: 519442:HUTA_RS10350
uniprot id: C7NU36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS04455
gene id: 519442:HUTA_RS04455
uniprot id: C7NUT0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS11580
gene id: 519442:HUTA_RS11580
uniprot id: C7NVK8
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

519442:HUTA RS12075
gene id: 519442:HUTA_RS12075
uniprot id: C7NMI5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

519442:HUTA RS05795
gene id: 519442:HUTA_RS05795
uniprot id: C7NMQ0
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

519442:HUTA RS12325
gene id: 519442:HUTA_RS12325
uniprot id: C7NMX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

519442:HUTA RS07830
gene id: 519442:HUTA_RS07830
uniprot id: C7NQ36
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

519442:HUTA RS12505
gene id: 519442:HUTA_RS12505
uniprot id: C7NPF6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

519442:HUTA RS04775
gene id: 519442:HUTA_RS04775
uniprot id: C7NUZ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

519442:HUTA RS12470
gene id: 519442:HUTA_RS12470
uniprot id: C7NN05
names: Similarity
messages: Belongs to the citrate synthase family.

519442:HUTA RS13710
gene id: 519442:HUTA_RS13710
uniprot id: C7NR49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

519442:HUTA RS13125
gene id: 519442:HUTA_RS13125
uniprot id: C7NQB2
names: Similarity
messages: Belongs to the UPF0440 family.

519442:HUTA RS05380
gene id: 519442:HUTA_RS05380
uniprot id: C7NM73
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

519442:HUTA RS01365
gene id: 519442:HUTA_RS01365
uniprot id: C7NQL0
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

519442:HUTA RS02105
gene id: 519442:HUTA_RS02105
uniprot id: C7NS07
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS02465
gene id: 519442:HUTA_RS02465
uniprot id: C7NS80
names: Similarity
messages: Belongs to the peptidase M24B family.

519442:HUTA RS09565
gene id: 519442:HUTA_RS09565
uniprot id: C7NT48
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Part of the 30S ribosomal subunit.

519442:HUTA RS03290
gene id: 519442:HUTA_RS03290
uniprot id: C7NTD6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

519442:HUTA RS07495
gene id: 519442:HUTA_RS07495
uniprot id: C7NPC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

519442:HUTA RS14565
gene id: 519442:HUTA_RS14565
uniprot id: C7NSL7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

519442:HUTA RS06480
gene id: 519442:HUTA_RS06480
uniprot id: C7NNA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

519442:HUTA RS14765
gene id: 519442:HUTA_RS14765
uniprot id: C7NSN9
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

519442:HUTA RS06095
gene id: 519442:HUTA_RS06095
uniprot id: C7NN26
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS01925
gene id: 519442:HUTA_RS01925
uniprot id: C7NRE3
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

519442:HUTA RS07330
gene id: 519442:HUTA_RS07330
uniprot id: C7NP90
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

519442:HUTA RS07300
gene id: 519442:HUTA_RS07300
uniprot id: C7NP84
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

519442:HUTA RS06885
gene id: 519442:HUTA_RS06885
uniprot id: C7NNR1
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS05590
gene id: 519442:HUTA_RS05590
uniprot id: C7NMB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

519442:HUTA RS03470
gene id: 519442:HUTA_RS03470
uniprot id: C7NTQ6
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS01985
gene id: 519442:HUTA_RS01985
uniprot id: C7NRF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

519442:HUTA RS10270
gene id: 519442:HUTA_RS10270
uniprot id: C7NU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

519442:HUTA RS09370
gene id: 519442:HUTA_RS09370
uniprot id: C7NT11
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS11545
gene id: 519442:HUTA_RS11545
uniprot id: C7NVK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

519442:HUTA RS14560
gene id: 519442:HUTA_RS14560
uniprot id: C7NSL6
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS12765
gene id: 519442:HUTA_RS12765
uniprot id: C7NPK8
names: Similarity
messages: Belongs to the PdaD family.

519442:HUTA RS01735
gene id: 519442:HUTA_RS01735
uniprot id: C7NRA7
names: Subcellular Location Annotation
messages: Cytoplasm

519442:HUTA RS01610
gene id: 519442:HUTA_RS01610
uniprot id: C7NQR0
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

519442:HUTA RS05600
gene id: 519442:HUTA_RS05600
uniprot id: C7NMB5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

519442:HUTA RS05935
gene id: 519442:HUTA_RS05935
uniprot id: C7NMT0
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS05645
gene id: 519442:HUTA_RS05645
uniprot id: C7NML9
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

519442:HUTA RS05610
gene id: 519442:HUTA_RS05610
uniprot id: C7NMB7
names: Subunit
messages: Homotetramer.

519442:HUTA RS10430
gene id: 519442:HUTA_RS10430
uniprot id: C7NU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

519442:HUTA RS04830
gene id: 519442:HUTA_RS04830
uniprot id: C7NV85
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

519442:HUTA RS07700
gene id: 519442:HUTA_RS07700
uniprot id: C7NQ10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

519442:HUTA RS05400
gene id: 519442:HUTA_RS05400
uniprot id: C7NM78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

519442:HUTA RS04850
gene id: 519442:HUTA_RS04850
uniprot id: C7NV89
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

519442:HUTA RS11535
gene id: 519442:HUTA_RS11535
uniprot id: C7NVJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

519442:HUTA RS09830
gene id: 519442:HUTA_RS09830
uniprot id: C7NTI6
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

519442:HUTA RS00110
gene id: 519442:HUTA_RS00110
uniprot id: C7NNI3
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS14010
gene id: 519442:HUTA_RS14010
uniprot id: C7NRR6
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS01915
gene id: 519442:HUTA_RS01915
uniprot id: C7NRE1
names: Similarity
messages: Belongs to the HypE family.

519442:HUTA RS10330
gene id: 519442:HUTA_RS10330
uniprot id: C7NU32
names: Similarity
messages: Belongs to the glutaredoxin family.

519442:HUTA RS06765
gene id: 519442:HUTA_RS06765
uniprot id: C7NNG2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

519442:HUTA RS13590
gene id: 519442:HUTA_RS13590
uniprot id: C7NR22
names: Similarity
messages: Belongs to the UPF0212 family.

519442:HUTA RS03975
gene id: 519442:HUTA_RS03975
uniprot id: C7NU99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

519442:HUTA RS07090
gene id: 519442:HUTA_RS07090
uniprot id: C7NNV2
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

519442:HUTA RS05890
gene id: 519442:HUTA_RS05890
uniprot id: C7NMS1
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS07410
gene id: 519442:HUTA_RS07410
uniprot id: C7NPA8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

519442:HUTA RS14670
gene id: 519442:HUTA_RS14670
uniprot id: C7NRY1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

519442:HUTA RS11270
gene id: 519442:HUTA_RS11270
uniprot id: C7NV57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

519442:HUTA RS05085
gene id: 519442:HUTA_RS05085
uniprot id: C7NVD7
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

519442:HUTA RS01785
gene id: 519442:HUTA_RS01785
uniprot id: C7NRB7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

519442:HUTA RS03785
gene id: 519442:HUTA_RS03785
uniprot id: C7NTW9
names: Subcellular Location Annotation
messages: Cytoplasm

519442:HUTA RS09440
gene id: 519442:HUTA_RS09440
uniprot id: C7NT23
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

519442:HUTA RS01615
gene id: 519442:HUTA_RS01615
uniprot id: C7NQR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS12345
gene id: 519442:HUTA_RS12345
uniprot id: C7NMY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

519442:HUTA RS13600
gene id: 519442:HUTA_RS13600
uniprot id: C7NR24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

519442:HUTA RS04490
gene id: 519442:HUTA_RS04490
uniprot id: C7NUT7
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

519442:HUTA RS00345
gene id: 519442:HUTA_RS00345
uniprot id: C7NNN0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS06995
gene id: 519442:HUTA_RS06995
uniprot id: C7NNT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

519442:HUTA RS11255
gene id: 519442:HUTA_RS11255
uniprot id: C7NV54
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

519442:HUTA RS07305
gene id: 519442:HUTA_RS07305
uniprot id: C7NP85
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS00175
gene id: 519442:HUTA_RS00175
uniprot id: C7NNJ6
names: Subunit
messages: Homotrimer.

519442:HUTA RS02350
gene id: 519442:HUTA_RS02350
uniprot id: C7NS57
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

519442:HUTA RS10345
gene id: 519442:HUTA_RS10345
uniprot id: C7NU35
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

519442:HUTA RS12565
gene id: 519442:HUTA_RS12565
uniprot id: C7NPG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

519442:HUTA RS08855
gene id: 519442:HUTA_RS08855
uniprot id: C7NRP8
names: Subcellular Location Annotation
messages: Cytoplasm

519442:HUTA RS00625
gene id: 519442:HUTA_RS00625
uniprot id: C7NP26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

519442:HUTA RS12775
gene id: 519442:HUTA_RS12775
uniprot id: C7NPL0
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

519442:HUTA RS05750
gene id: 519442:HUTA_RS05750
uniprot id: C7NMP1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS05800
gene id: 519442:HUTA_RS05800
uniprot id: C7NMQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

519442:HUTA RS09030
gene id: 519442:HUTA_RS09030
uniprot id: C7NSC9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS11415
gene id: 519442:HUTA_RS11415
uniprot id: C7NVH6
names: Similarity
messages: Belongs to the HypD family.

519442:HUTA RS02010
gene id: 519442:HUTA_RS02010
uniprot id: C7NRF8
names: Similarity
messages: Belongs to the UPF0047 family.

519442:HUTA RS02795
gene id: 519442:HUTA_RS02795
uniprot id: C7NSU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

519442:HUTA RS12585
gene id: 519442:HUTA_RS12585
uniprot id: C7NPH2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

519442:HUTA RS02645
gene id: 519442:HUTA_RS02645
uniprot id: C7NSR3
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS11010
gene id: 519442:HUTA_RS11010
uniprot id: C7NV05
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

519442:HUTA RS13700
gene id: 519442:HUTA_RS13700
uniprot id: C7NR47
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

519442:HUTA RS02900
gene id: 519442:HUTA_RS02900
uniprot id: C7NSW5
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

519442:HUTA RS12845
gene id: 519442:HUTA_RS12845
uniprot id: C7NPM5
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

519442:HUTA RS10805
gene id: 519442:HUTA_RS10805
uniprot id: C7NUL9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

519442:HUTA RS03110
gene id: 519442:HUTA_RS03110
uniprot id: C7NT99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

519442:HUTA RS11315
gene id: 519442:HUTA_RS11315
uniprot id: C7NV66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

519442:HUTA RS05030
gene id: 519442:HUTA_RS05030
uniprot id: C7NVC6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

519442:HUTA RS02975
gene id: 519442:HUTA_RS02975
uniprot id: C7NSY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

519442:HUTA RS05820
gene id: 519442:HUTA_RS05820
uniprot id: C7NMQ5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

519442:HUTA RS04995
gene id: 519442:HUTA_RS04995
uniprot id: C7NVB9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS15955
gene id: 519442:HUTA_RS15955
uniprot id: C7NMH6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

519442:HUTA RS00440
gene id: 519442:HUTA_RS00440
uniprot id: C7NNY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

519442:HUTA RS03750
gene id: 519442:HUTA_RS03750
uniprot id: C7NTW2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

519442:HUTA RS13185
gene id: 519442:HUTA_RS13185
uniprot id: C7NQC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

519442:HUTA RS07340
gene id: 519442:HUTA_RS07340
uniprot id: C7NP93
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS04085
gene id: 519442:HUTA_RS04085
uniprot id: C7NUC2
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

519442:HUTA RS07170
gene id: 519442:HUTA_RS07170
uniprot id: C7NNW9
names: Similarity
messages: Belongs to the PEPCase type 1 family.

519442:HUTA RS02475
gene id: 519442:HUTA_RS02475
uniprot id: C7NS82
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

519442:HUTA RS02320
gene id: 519442:HUTA_RS02320
uniprot id: C7NS51
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

519442:HUTA RS12360
gene id: 519442:HUTA_RS12360
uniprot id: C7NMY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

519442:HUTA RS14520
gene id: 519442:HUTA_RS14520
uniprot id: C7NSK9
names: Similarity
messages: Belongs to the SCO1/2 family.

519442:HUTA RS11310
gene id: 519442:HUTA_RS11310
uniprot id: C7NV65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

519442:HUTA RS09910
gene id: 519442:HUTA_RS09910
uniprot id: C7NTK4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

519442:HUTA RS10360
gene id: 519442:HUTA_RS10360
uniprot id: C7NU38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519442:HUTA RS02765
gene id: 519442:HUTA_RS02765
uniprot id: C7NST8
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS11335
gene id: 519442:HUTA_RS11335
uniprot id: C7NV70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

519442:HUTA RS12510
gene id: 519442:HUTA_RS12510
uniprot id: C7NPF7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

519442:HUTA RS02595
gene id: 519442:HUTA_RS02595
uniprot id: C7NSQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

519442:HUTA RS04600
gene id: 519442:HUTA_RS04600
uniprot id: C7NUV9
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

519442:HUTA RS04055
gene id: 519442:HUTA_RS04055
uniprot id: C7NUB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

519442:HUTA RS03250
gene id: 519442:HUTA_RS03250
uniprot id: C7NTC8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.

519442:HUTA RS12005
gene id: 519442:HUTA_RS12005
uniprot id: C7NMH4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

519442:HUTA RS03450
gene id: 519442:HUTA_RS03450
uniprot id: C7NTQ2
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

519442:HUTA RS09580
gene id: 519442:HUTA_RS09580
uniprot id: C7NT51
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS06645
gene id: 519442:HUTA_RS06645
uniprot id: C7NND6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

519442:HUTA RS02530
gene id: 519442:HUTA_RS02530
uniprot id: C7NS93
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

519442:HUTA RS12130
gene id: 519442:HUTA_RS12130
uniprot id: C7NMJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

519442:HUTA RS11250
gene id: 519442:HUTA_RS11250
uniprot id: C7NV53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

519442:HUTA RS07770
gene id: 519442:HUTA_RS07770
uniprot id: C7NQ25
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

519442:HUTA RS14435
gene id: 519442:HUTA_RS14435
uniprot id: C7NSJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS05770
gene id: 519442:HUTA_RS05770
uniprot id: C7NMP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

519442:HUTA RS00290
gene id: 519442:HUTA_RS00290
uniprot id: C7NNL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

519442:HUTA RS04805
gene id: 519442:HUTA_RS04805
uniprot id: C7NV79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

519442:HUTA RS13295
gene id: 519442:HUTA_RS13295
uniprot id: C7NQE9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS05895
gene id: 519442:HUTA_RS05895
uniprot id: C7NMS2
names: Function
messages: Part of a potassium transport system.

519442:HUTA RS07505
gene id: 519442:HUTA_RS07505
uniprot id: C7NPC7
names: Function
messages: Part of a potassium transport system.

519442:HUTA RS05065
gene id: 519442:HUTA_RS05065
uniprot id: C7NVD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

519442:HUTA RS06075
gene id: 519442:HUTA_RS06075
uniprot id: C7NN21
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS03465
gene id: 519442:HUTA_RS03465
uniprot id: C7NTQ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS09855
gene id: 519442:HUTA_RS09855
uniprot id: C7NTJ1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

519442:HUTA RS07205
gene id: 519442:HUTA_RS07205
uniprot id: C7NP64
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

519442:HUTA RS13040
gene id: 519442:HUTA_RS13040
uniprot id: C7NQ95
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

519442:HUTA RS08920
gene id: 519442:HUTA_RS08920
uniprot id: C7NSB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.

519442:HUTA RS11765
gene id: 519442:HUTA_RS11765
uniprot id: C7NMC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

519442:HUTA RS05210
gene id: 519442:HUTA_RS05210
uniprot id: C7NVG2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

519442:HUTA RS01740
gene id: 519442:HUTA_RS01740
uniprot id: C7NRA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

519442:HUTA RS03080
gene id: 519442:HUTA_RS03080
uniprot id: C7NT92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

519442:HUTA RS12540
gene id: 519442:HUTA_RS12540
uniprot id: C7NPG3
names: Similarity
messages: Belongs to the UPF0175 family.

519442:HUTA RS09665
gene id: 519442:HUTA_RS09665
uniprot id: C7NT68
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS13405
gene id: 519442:HUTA_RS13405
uniprot id: C7NPQ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

519442:HUTA RS04450
gene id: 519442:HUTA_RS04450
uniprot id: C7NUS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

519442:HUTA RS14420
gene id: 519442:HUTA_RS14420
uniprot id: C7NSI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

519442:HUTA RS04895
gene id: 519442:HUTA_RS04895
uniprot id: C7NV98
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

519442:HUTA RS01255
gene id: 519442:HUTA_RS01255
uniprot id: C7NQI7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

519442:HUTA RS01385
gene id: 519442:HUTA_RS01385
uniprot id: C7NQL4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

519442:HUTA RS11440
gene id: 519442:HUTA_RS11440
uniprot id: C7NVI0
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

519442:HUTA RS12335
gene id: 519442:HUTA_RS12335
uniprot id: C7NMY0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

519442:HUTA RS08655
gene id: 519442:HUTA_RS08655
uniprot id: C7NRL1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

519442:HUTA RS13335
gene id: 519442:HUTA_RS13335
uniprot id: C7NQF7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

519442:HUTA RS05930
gene id: 519442:HUTA_RS05930
uniprot id: C7NMS9
names: Function
messages: Part of a potassium transport system.

519442:HUTA RS11700
gene id: 519442:HUTA_RS11700
uniprot id: C7NVN2
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

519442:HUTA RS04435
gene id: 519442:HUTA_RS04435
uniprot id: C7NUS5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS11655
gene id: 519442:HUTA_RS11655
uniprot id: C7NVM3
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

519442:HUTA RS07355
gene id: 519442:HUTA_RS07355
uniprot id: C7NP96
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

519442:HUTA RS06345
gene id: 519442:HUTA_RS06345
uniprot id: C7NN78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

519442:HUTA RS02245
gene id: 519442:HUTA_RS02245
uniprot id: C7NS35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Nucleus

519442:HUTA RS02525
gene id: 519442:HUTA_RS02525
uniprot id: C7NS92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS05350
gene id: 519442:HUTA_RS05350
uniprot id: C7NM67
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS12390
gene id: 519442:HUTA_RS12390
uniprot id: C7NMZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

519442:HUTA RS13555
gene id: 519442:HUTA_RS13555
uniprot id: C7NR14
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

519442:HUTA RS02440
gene id: 519442:HUTA_RS02440
uniprot id: C7NS75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

519442:HUTA RS03075
gene id: 519442:HUTA_RS03075
uniprot id: C7NT90
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

519442:HUTA RS11280
gene id: 519442:HUTA_RS11280
uniprot id: C7NV59
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

519442:HUTA RS07455
gene id: 519442:HUTA_RS07455
uniprot id: C7NPB7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

519442:HUTA RS06695
gene id: 519442:HUTA_RS06695
uniprot id: C7NNE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS11360
gene id: 519442:HUTA_RS11360
uniprot id: C7NVG4
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS12495
gene id: 519442:HUTA_RS12495
uniprot id: C7NPF3
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

519442:HUTA RS03020
gene id: 519442:HUTA_RS03020
uniprot id: C7NT79
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS04520
gene id: 519442:HUTA_RS04520
uniprot id: C7NUU3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

519442:HUTA RS12970
gene id: 519442:HUTA_RS12970
uniprot id: C7NQ80
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

519442:HUTA RS06940
gene id: 519442:HUTA_RS06940
uniprot id: C7NNS2
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS06600
gene id: 519442:HUTA_RS06600
uniprot id: C7NNC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

519442:HUTA RS06325
gene id: 519442:HUTA_RS06325
uniprot id: C7NN74
names: Similarity
messages: Belongs to the thymidylate kinase family.

519442:HUTA RS07440
gene id: 519442:HUTA_RS07440
uniprot id: C7NPB4
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

519442:HUTA RS12340
gene id: 519442:HUTA_RS12340
uniprot id: C7NMY1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

519442:HUTA RS06205
gene id: 519442:HUTA_RS06205
uniprot id: C7NN49
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

519442:HUTA RS08620
gene id: 519442:HUTA_RS08620
uniprot id: C7NRK4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

519442:HUTA RS06890
gene id: 519442:HUTA_RS06890
uniprot id: C7NNR2
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS14275
gene id: 519442:HUTA_RS14275
uniprot id: C7NR83
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS14825
gene id: 519442:HUTA_RS14825
uniprot id: C7NT75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

519442:HUTA RS05665
gene id: 519442:HUTA_RS05665
uniprot id: C7NMM3
names: Similarity
messages: Belongs to the AAA ATPase family.

519442:HUTA RS04225
gene id: 519442:HUTA_RS04225
uniprot id: C7NUE9
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

519442:HUTA RS12365
gene id: 519442:HUTA_RS12365
uniprot id: C7NMY6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

519442:HUTA RS04140
gene id: 519442:HUTA_RS04140
uniprot id: C7NUD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

519442:HUTA RS08615
gene id: 519442:HUTA_RS08615
uniprot id: C7NRK3
names: Similarity
messages: Belongs to the UPF0215 family.

519442:HUTA RS02610
gene id: 519442:HUTA_RS02610
uniprot id: C7NSQ6
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS07850
gene id: 519442:HUTA_RS07850
uniprot id: C7NQ40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

519442:HUTA RS03015
gene id: 519442:HUTA_RS03015
uniprot id: C7NT78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

519442:HUTA RS08780
gene id: 519442:HUTA_RS08780
uniprot id: C7NRN4
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

519442:HUTA RS02780
gene id: 519442:HUTA_RS02780
uniprot id: C7NSU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS02260
gene id: 519442:HUTA_RS02260
uniprot id: C7NS38
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

519442:HUTA RS00785
gene id: 519442:HUTA_RS00785
uniprot id: C7NP59
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS04860
gene id: 519442:HUTA_RS04860
uniprot id: C7NV91
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

519442:HUTA RS10645
gene id: 519442:HUTA_RS10645
uniprot id: C7NUI7
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

519442:HUTA RS05760
gene id: 519442:HUTA_RS05760
uniprot id: C7NMP3
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

519442:HUTA RS07380
gene id: 519442:HUTA_RS07380
uniprot id: C7NPA1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

519442:HUTA RS12615
gene id: 519442:HUTA_RS12615
uniprot id: C7NPH8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS14665
gene id: 519442:HUTA_RS14665
uniprot id: C7NRY0
names: Similarity
messages: Belongs to the MEMO1 family.

519442:HUTA RS13825
gene id: 519442:HUTA_RS13825
uniprot id: C7NR73
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

519442:HUTA RS07040
gene id: 519442:HUTA_RS07040
uniprot id: C7NNU2
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

519442:HUTA RS08225
gene id: 519442:HUTA_RS08225
uniprot id: C7NQV1
names: Similarity
messages: Belongs to the UPF0175 family.

519442:HUTA RS04955
gene id: 519442:HUTA_RS04955
uniprot id: C7NVB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

519442:HUTA RS03150
gene id: 519442:HUTA_RS03150
uniprot id: C7NTA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

519442:HUTA RS10725
gene id: 519442:HUTA_RS10725
uniprot id: C7NUK3
names: Subcellular Location Annotation
messages: Cytoplasm

519442:HUTA RS09265
gene id: 519442:HUTA_RS09265
uniprot id: C7NSZ0
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

519442:HUTA RS01695
gene id: 519442:HUTA_RS01695
uniprot id: C7NR99
names: Similarity
messages: Belongs to the peptidase C56 family.

519442:HUTA RS01800
gene id: 519442:HUTA_RS01800
uniprot id: C7NRC0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

519442:HUTA RS06820
gene id: 519442:HUTA_RS06820
uniprot id: C7NNP8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

519442:HUTA RS04335
gene id: 519442:HUTA_RS04335
uniprot id: C7NUQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

519442:HUTA RS03145
gene id: 519442:HUTA_RS03145
uniprot id: C7NTA6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS02295
gene id: 519442:HUTA_RS02295
uniprot id: C7NS45
names: Similarity
messages: Belongs to the HypE family.

519442:HUTA RS13525
gene id: 519442:HUTA_RS13525
uniprot id: C7NR08
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

519442:HUTA RS05080
gene id: 519442:HUTA_RS05080
uniprot id: C7NVD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

519442:HUTA RS13180
gene id: 519442:HUTA_RS13180
uniprot id: C7NQC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

519442:HUTA RS02375
gene id: 519442:HUTA_RS02375
uniprot id: C7NS62
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

519442:HUTA RS07075
gene id: 519442:HUTA_RS07075
uniprot id: C7NNU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

519442:HUTA RS06475
gene id: 519442:HUTA_RS06475
uniprot id: C7NNA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

519442:HUTA RS08975
gene id: 519442:HUTA_RS08975
uniprot id: C7NSB9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

519442:HUTA RS07740
gene id: 519442:HUTA_RS07740
uniprot id: C7NQ18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

519442:HUTA RS01605
gene id: 519442:HUTA_RS01605
uniprot id: C7NQQ9
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS16015
gene id: 519442:HUTA_RS16015
uniprot id: C7NV03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

519442:HUTA RS04710
gene id: 519442:HUTA_RS04710
uniprot id: C7NUY1
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS01495
gene id: 519442:HUTA_RS01495
uniprot id: C7NQN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

519442:HUTA RS13020
gene id: 519442:HUTA_RS13020
uniprot id: C7NQ91
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

519442:HUTA RS08735
gene id: 519442:HUTA_RS08735
uniprot id: C7NRM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

519442:HUTA RS04645
gene id: 519442:HUTA_RS04645
uniprot id: C7NUW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

519442:HUTA RS14605
gene id: 519442:HUTA_RS14605
uniprot id: C7NSM6
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS12695
gene id: 519442:HUTA_RS12695
uniprot id: C7NPJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519442:HUTA RS05265
gene id: 519442:HUTA_RS05265
uniprot id: C7NM50
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

519442:HUTA RS14710
gene id: 519442:HUTA_RS14710
uniprot id: C7NRY9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

519442:HUTA RS12705
gene id: 519442:HUTA_RS12705
uniprot id: C7NPJ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS00360
gene id: 519442:HUTA_RS00360
uniprot id: C7NNN3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

519442:HUTA RS03180
gene id: 519442:HUTA_RS03180
uniprot id: C7NTB4
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.

519442:HUTA RS07525
gene id: 519442:HUTA_RS07525
uniprot id: C7NPD2
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

519442:HUTA RS12630
gene id: 519442:HUTA_RS12630
uniprot id: C7NPI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

519442:HUTA RS00235
gene id: 519442:HUTA_RS00235
uniprot id: C7NNK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

519442:HUTA RS13330
gene id: 519442:HUTA_RS13330
uniprot id: C7NQF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

519442:HUTA RS01475
gene id: 519442:HUTA_RS01475
uniprot id: C7NQN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

519442:HUTA RS02430
gene id: 519442:HUTA_RS02430
uniprot id: C7NS73
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA.

519442:HUTA RS08170
gene id: 519442:HUTA_RS08170
uniprot id: C7NQU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

519442:HUTA RS03840
gene id: 519442:HUTA_RS03840
uniprot id: C7NTX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

519442:HUTA RS14195
gene id: 519442:HUTA_RS14195
uniprot id: C7NRV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

519442:HUTA RS07595
gene id: 519442:HUTA_RS07595
uniprot id: C7NPE6
names: Similarity
messages: Belongs to the IMPACT family.

519442:HUTA RS10760
gene id: 519442:HUTA_RS10760
uniprot id: C7NUL0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

519442:HUTA RS10335
gene id: 519442:HUTA_RS10335
uniprot id: C7NU33
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

519442:HUTA RS00675
gene id: 519442:HUTA_RS00675
uniprot id: C7NP36
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS14105
gene id: 519442:HUTA_RS14105
uniprot id: C7NRT6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

519442:HUTA RS10665
gene id: 519442:HUTA_RS10665
uniprot id: C7NUJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

519442:HUTA RS07995
gene id: 519442:HUTA_RS07995
uniprot id: C7NQ69
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.

519442:HUTA RS11665
gene id: 519442:HUTA_RS11665
uniprot id: C7NVM5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

519442:HUTA RS14155
gene id: 519442:HUTA_RS14155
uniprot id: C7NRU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS07080
gene id: 519442:HUTA_RS07080
uniprot id: C7NNV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

519442:HUTA RS10235
gene id: 519442:HUTA_RS10235
uniprot id: C7NU12
names: Similarity
messages: Belongs to the UPF0201 family.

519442:HUTA RS09545
gene id: 519442:HUTA_RS09545
uniprot id: C7NT44
names: Similarity
messages: Belongs to the HepT RNase toxin family.

519442:HUTA RS06420
gene id: 519442:HUTA_RS06420
uniprot id: C7NN93
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS08890
gene id: 519442:HUTA_RS08890
uniprot id: C7NSA4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS11320
gene id: 519442:HUTA_RS11320
uniprot id: C7NV67
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

519442:HUTA RS12230
gene id: 519442:HUTA_RS12230
uniprot id: C7NMV8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS07780
gene id: 519442:HUTA_RS07780
uniprot id: C7NQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

519442:HUTA RS14580
gene id: 519442:HUTA_RS14580
uniprot id: C7NSM0
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS12515
gene id: 519442:HUTA_RS12515
uniprot id: C7NPF8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

519442:HUTA RS06630
gene id: 519442:HUTA_RS06630
uniprot id: C7NND3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

519442:HUTA RS10840
gene id: 519442:HUTA_RS10840
uniprot id: C7NUM6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

519442:HUTA RS01245
gene id: 519442:HUTA_RS01245
uniprot id: C7NQI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

519442:HUTA RS09905
gene id: 519442:HUTA_RS09905
uniprot id: C7NTK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

519442:HUTA RS09660
gene id: 519442:HUTA_RS09660
uniprot id: C7NT67
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS05705
gene id: 519442:HUTA_RS05705
uniprot id: C7NMN2
names: Similarity
messages: Belongs to the TrpC family.

519442:HUTA RS01655
gene id: 519442:HUTA_RS01655
uniprot id: C7NQR9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS01180
gene id: 519442:HUTA_RS01180
uniprot id: C7NPY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

519442:HUTA RS12860
gene id: 519442:HUTA_RS12860
uniprot id: C7NPM8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

519442:HUTA RS12580
gene id: 519442:HUTA_RS12580
uniprot id: C7NPH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

519442:HUTA RS01835
gene id: 519442:HUTA_RS01835
uniprot id: C7NRC7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

519442:HUTA RS08070
gene id: 519442:HUTA_RS08070
uniprot id: C7NQS4
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS03530
gene id: 519442:HUTA_RS03530
uniprot id: C7NTR8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

519442:HUTA RS07120
gene id: 519442:HUTA_RS07120
uniprot id: C7NNV9
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS02730
gene id: 519442:HUTA_RS02730
uniprot id: C7NST1
names: Similarity
messages: Belongs to the FUN14 family.

519442:HUTA RS10835
gene id: 519442:HUTA_RS10835
uniprot id: C7NUM5
names: Similarity
messages: Belongs to the AAA ATPase family.

519442:HUTA RS00375
gene id: 519442:HUTA_RS00375
uniprot id: C7NNX5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

519442:HUTA RS05855
gene id: 519442:HUTA_RS05855
uniprot id: C7NMR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

519442:HUTA RS06150
gene id: 519442:HUTA_RS06150
uniprot id: C7NN37
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

519442:HUTA RS12900
gene id: 519442:HUTA_RS12900
uniprot id: C7NMK6
names: Similarity
messages: Belongs to the pirin family.

519442:HUTA RS14585
gene id: 519442:HUTA_RS14585
uniprot id: C7NSM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

519442:HUTA RS03845
gene id: 519442:HUTA_RS03845
uniprot id: C7NTY0
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Part of the RNA polymerase complex.

519442:HUTA RS09850
gene id: 519442:HUTA_RS09850
uniprot id: C7NTJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

519442:HUTA RS11330
gene id: 519442:HUTA_RS11330
uniprot id: C7NV69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

519442:HUTA RS11340
gene id: 519442:HUTA_RS11340
uniprot id: C7NV71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

519442:HUTA RS12035
gene id: 519442:HUTA_RS12035
uniprot id: C7NMI0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

519442:HUTA RS04585
gene id: 519442:HUTA_RS04585
uniprot id: C7NUV6
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS13585
gene id: 519442:HUTA_RS13585
uniprot id: C7NR20
names: Subcellular Location Annotation
messages: Cytoplasm

519442:HUTA RS13415
gene id: 519442:HUTA_RS13415
uniprot id: C7NPQ4
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS06880
gene id: 519442:HUTA_RS06880
uniprot id: C7NNR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

519442:HUTA RS01930
gene id: 519442:HUTA_RS01930
uniprot id: C7NRE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

519442:HUTA RS05945
gene id: 519442:HUTA_RS05945
uniprot id: C7NMT2
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

519442:HUTA RS12445
gene id: 519442:HUTA_RS12445
uniprot id: C7NN00
names: Similarity
messages: Belongs to the SUI1 family.

519442:HUTA RS05385
gene id: 519442:HUTA_RS05385
uniprot id: C7NM74
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

519442:HUTA RS04835
gene id: 519442:HUTA_RS04835
uniprot id: C7NV86
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

519442:HUTA RS10020
gene id: 519442:HUTA_RS10020
uniprot id: C7NTM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

519442:HUTA RS01530
gene id: 519442:HUTA_RS01530
uniprot id: C7NQP4
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS14265
gene id: 519442:HUTA_RS14265
uniprot id: C7NRW8
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS01105
gene id: 519442:HUTA_RS01105
uniprot id: C7NPW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

519442:HUTA RS02000
gene id: 519442:HUTA_RS02000
uniprot id: C7NRF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

519442:HUTA RS01185
gene id: 519442:HUTA_RS01185
uniprot id: C7NPY5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS12380
gene id: 519442:HUTA_RS12380
uniprot id: C7NMY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

519442:HUTA RS00415
gene id: 519442:HUTA_RS00415
uniprot id: C7NNY3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

519442:HUTA RS02040
gene id: 519442:HUTA_RS02040
uniprot id: C7NRG4
names: Similarity
messages: Belongs to the UPF0179 family.

519442:HUTA RS11030
gene id: 519442:HUTA_RS11030
uniprot id: C7NV08
names: Similarity
messages: Belongs to the phosphohexose mutase family.

519442:HUTA RS11225
gene id: 519442:HUTA_RS11225
uniprot id: C7NV48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

519442:HUTA RS13380
gene id: 519442:HUTA_RS13380
uniprot id: C7NPP6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

519442:HUTA RS10005
gene id: 519442:HUTA_RS10005
uniprot id: C7NTM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Homodimer.

519442:HUTA RS01415
gene id: 519442:HUTA_RS01415
uniprot id: C7NQM1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

519442:HUTA RS07270
gene id: 519442:HUTA_RS07270
uniprot id: C7NP77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

519442:HUTA RS13475
gene id: 519442:HUTA_RS13475
uniprot id: C7NQG8
names: Similarity
messages: Belongs to the UPF0173 family.

519442:HUTA RS11885
gene id: 519442:HUTA_RS11885
uniprot id: C7NMF1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

519442:HUTA RS13065
gene id: 519442:HUTA_RS13065
uniprot id: C7NQA0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

519442:HUTA RS08375
gene id: 519442:HUTA_RS08375
uniprot id: C7NQY3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

519442:HUTA RS10465
gene id: 519442:HUTA_RS10465
uniprot id: C7NU59
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS11325
gene id: 519442:HUTA_RS11325
uniprot id: C7NV68
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

519442:HUTA RS04265
gene id: 519442:HUTA_RS04265
uniprot id: C7NUF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 67 family.

519442:HUTA RS05970
gene id: 519442:HUTA_RS05970
uniprot id: C7NMT7
names: Similarity
messages: Belongs to the HepT RNase toxin family.

519442:HUTA RS12735
gene id: 519442:HUTA_RS12735
uniprot id: C7NPK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

519442:HUTA RS07825
gene id: 519442:HUTA_RS07825
uniprot id: C7NQ35
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

519442:HUTA RS12640
gene id: 519442:HUTA_RS12640
uniprot id: C7NPI2
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

519442:HUTA RS13665
gene id: 519442:HUTA_RS13665
uniprot id: C7NR37
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

519442:HUTA RS10935
gene id: 519442:HUTA_RS10935
uniprot id: C7NUP6
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS07390
gene id: 519442:HUTA_RS07390
uniprot id: C7NPA3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS01825
gene id: 519442:HUTA_RS01825
uniprot id: C7NRC5
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

519442:HUTA RS10390
gene id: 519442:HUTA_RS10390
uniprot id: C7NU44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

519442:HUTA RS12205
gene id: 519442:HUTA_RS12205
uniprot id: C7NMV3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

519442:HUTA RS03055
gene id: 519442:HUTA_RS03055
uniprot id: C7NT86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

519442:HUTA RS11370
gene id: 519442:HUTA_RS11370
uniprot id: C7NVG6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

519442:HUTA RS11275
gene id: 519442:HUTA_RS11275
uniprot id: C7NV58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

519442:HUTA RS10600
gene id: 519442:HUTA_RS10600
uniprot id: C7NUH8
names: Similarity
messages: Belongs to the TFIIB family.

519442:HUTA RS10770
gene id: 519442:HUTA_RS10770
uniprot id: C7NUL2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

519442:HUTA RS07145
gene id: 519442:HUTA_RS07145
uniprot id: C7NNW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

519442:HUTA RS05570
gene id: 519442:HUTA_RS05570
uniprot id: C7NMA9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

519442:HUTA RS06570
gene id: 519442:HUTA_RS06570
uniprot id: C7NNC3
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

519442:HUTA RS11395
gene id: 519442:HUTA_RS11395
uniprot id: C7NVH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

519442:HUTA RS07310
gene id: 519442:HUTA_RS07310
uniprot id: C7NP86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

519442:HUTA RS03315
gene id: 519442:HUTA_RS03315
uniprot id: C7NTE1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

519442:HUTA RS06955
gene id: 519442:HUTA_RS06955
uniprot id: C7NNS5
names: Similarity
messages: Belongs to the glutamate synthase family.

519442:HUTA RS10795
gene id: 519442:HUTA_RS10795
uniprot id: C7NUL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

519442:HUTA RS06895
gene id: 519442:HUTA_RS06895
uniprot id: C7NNR3
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS06810
gene id: 519442:HUTA_RS06810
uniprot id: C7NNP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the oxidation of methyl-H(4)MPT to methylene-H(4)MPT.
messages: Cytoplasm

519442:HUTA RS09925
gene id: 519442:HUTA_RS09925
uniprot id: C7NTK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

519442:HUTA RS10175
gene id: 519442:HUTA_RS10175
uniprot id: C7NTZ9
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS00645
gene id: 519442:HUTA_RS00645
uniprot id: C7NP30
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

519442:HUTA RS05615
gene id: 519442:HUTA_RS05615
uniprot id: C7NMB8
names: Similarity
messages: Belongs to the FGGY kinase family.

519442:HUTA RS14305
gene id: 519442:HUTA_RS14305
uniprot id: C7NR89
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

519442:HUTA RS04075
gene id: 519442:HUTA_RS04075
uniprot id: C7NUC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

519442:HUTA RS07245
gene id: 519442:HUTA_RS07245
uniprot id: C7NP72
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

519442:HUTA RS09675
gene id: 519442:HUTA_RS09675
uniprot id: C7NT70
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS05015
gene id: 519442:HUTA_RS05015
uniprot id: C7NVC3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

519442:HUTA RS12895
gene id: 519442:HUTA_RS12895
uniprot id: C7NMK5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS12800
gene id: 519442:HUTA_RS12800
uniprot id: C7NPL5
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS11345
gene id: 519442:HUTA_RS11345
uniprot id: C7NV72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS03070
gene id: 519442:HUTA_RS03070
uniprot id: C7NT89
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

519442:HUTA RS11920
gene id: 519442:HUTA_RS11920
uniprot id: C7NMF8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

519442:HUTA RS00260
gene id: 519442:HUTA_RS00260
uniprot id: C7NNL3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

519442:HUTA RS01805
gene id: 519442:HUTA_RS01805
uniprot id: C7NRC1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

519442:HUTA RS02290
gene id: 519442:HUTA_RS02290
uniprot id: C7NS44
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

519442:HUTA RS11420
gene id: 519442:HUTA_RS11420
uniprot id: C7NVH7
names: Similarity
messages: Belongs to the HypE family.

519442:HUTA RS02115
gene id: 519442:HUTA_RS02115
uniprot id: C7NS09
names: Similarity
messages: Belongs to the PspA/IM30 family.

519442:HUTA RS11970
gene id: 519442:HUTA_RS11970
uniprot id: C7NMG7
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

519442:HUTA RS11490
gene id: 519442:HUTA_RS11490
uniprot id: C7NVJ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS10860
gene id: 519442:HUTA_RS10860
uniprot id: C7NUN1
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS09700
gene id: 519442:HUTA_RS09700
uniprot id: C7NTG0
names: Similarity
messages: Belongs to the PDCD5 family.

519442:HUTA RS03000
gene id: 519442:HUTA_RS03000
uniprot id: C7NSY5
names: Subcellular Location Annotation
messages: Cytoplasm

519442:HUTA RS11065
gene id: 519442:HUTA_RS11065
uniprot id: C7NV15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

519442:HUTA RS03495
gene id: 519442:HUTA_RS03495
uniprot id: C7NTR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.

519442:HUTA RS06445
gene id: 519442:HUTA_RS06445
uniprot id: C7NN98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS04380
gene id: 519442:HUTA_RS04380
uniprot id: C7NUR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

519442:HUTA RS01905
gene id: 519442:HUTA_RS01905
uniprot id: C7NRD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519442:HUTA RS04890
gene id: 519442:HUTA_RS04890
uniprot id: C7NV97
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

519442:HUTA RS04170
gene id: 519442:HUTA_RS04170
uniprot id: C7NUD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

519442:HUTA RS02840
gene id: 519442:HUTA_RS02840
uniprot id: C7NSV3
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS09815
gene id: 519442:HUTA_RS09815
uniprot id: C7NTI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

519442:HUTA RS13735
gene id: 519442:HUTA_RS13735
uniprot id: C7NR54
names: Similarity
messages: Belongs to the SDO1/SBDS family.

519442:HUTA RS07230
gene id: 519442:HUTA_RS07230
uniprot id: C7NP69
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

519442:HUTA RS05640
gene id: 519442:HUTA_RS05640
uniprot id: C7NML8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

519442:HUTA RS11785
gene id: 519442:HUTA_RS11785
uniprot id: C7NMD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

519442:HUTA RS13375
gene id: 519442:HUTA_RS13375
uniprot id: C7NPP5
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS04680
gene id: 519442:HUTA_RS04680
uniprot id: C7NUX5
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

519442:HUTA RS03025
gene id: 519442:HUTA_RS03025
uniprot id: C7NT80
names: Similarity
messages: Belongs to the UPF0107 family.

519442:HUTA RS04030
gene id: 519442:HUTA_RS04030
uniprot id: C7NUB0
names: Similarity
messages: Belongs to the UPF0212 family.

519442:HUTA RS11600
gene id: 519442:HUTA_RS11600
uniprot id: C7NVL2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS00780
gene id: 519442:HUTA_RS00780
uniprot id: C7NP58
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

519442:HUTA RS03135
gene id: 519442:HUTA_RS03135
uniprot id: C7NTA4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

519442:HUTA RS00640
gene id: 519442:HUTA_RS00640
uniprot id: C7NP29
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

519442:HUTA RS01235
gene id: 519442:HUTA_RS01235
uniprot id: C7NQI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

519442:HUTA RS09865
gene id: 519442:HUTA_RS09865
uniprot id: C7NTJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

519442:HUTA RS09650
gene id: 519442:HUTA_RS09650
uniprot id: C7NT65
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS08180
gene id: 519442:HUTA_RS08180
uniprot id: C7NQU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

519442:HUTA RS00490
gene id: 519442:HUTA_RS00490
uniprot id: C7NNZ9
names: Similarity
messages: Belongs to the HsdR family.

519442:HUTA RS10200
gene id: 519442:HUTA_RS10200
uniprot id: C7NU04
names: Subcellular Location Annotation
messages: Cytoplasm

519442:HUTA RS13920
gene id: 519442:HUTA_RS13920
uniprot id: C7NR78
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

519442:HUTA RS10225
gene id: 519442:HUTA_RS10225
uniprot id: C7NU09
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

519442:HUTA RS00005
gene id: 519442:HUTA_RS00005
uniprot id: C7NNG3
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

519442:HUTA RS06655
gene id: 519442:HUTA_RS06655
uniprot id: C7NND8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

519442:HUTA RS01910
gene id: 519442:HUTA_RS01910
uniprot id: C7NRE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS14760
gene id: 519442:HUTA_RS14760
uniprot id: C7NSN8
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS13395
gene id: 519442:HUTA_RS13395
uniprot id: C7NPP9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

519442:HUTA RS05925
gene id: 519442:HUTA_RS05925
uniprot id: C7NMS8
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS09560
gene id: 519442:HUTA_RS09560
uniprot id: C7NT47
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

519442:HUTA RS13230
gene id: 519442:HUTA_RS13230
uniprot id: C7NQD4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

519442:HUTA RS03620
gene id: 519442:HUTA_RS03620
uniprot id: C7NTT5
names: Cofactor
messages: Binds 1 copper ion per subunit.

519442:HUTA RS13490
gene id: 519442:HUTA_RS13490
uniprot id: C7NR01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

519442:HUTA RS03395
gene id: 519442:HUTA_RS03395
uniprot id: C7NTF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

519442:HUTA RS05170
gene id: 519442:HUTA_RS05170
uniprot id: C7NVF4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

519442:HUTA RS12905
gene id: 519442:HUTA_RS12905
uniprot id: C7NMK7
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS12030
gene id: 519442:HUTA_RS12030
uniprot id: C7NMH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

519442:HUTA RS10695
gene id: 519442:HUTA_RS10695
uniprot id: C7NUJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

519442:HUTA RS03850
gene id: 519442:HUTA_RS03850
uniprot id: C7NTY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

519442:HUTA RS04515
gene id: 519442:HUTA_RS04515
uniprot id: C7NUU2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

519442:HUTA RS09840
gene id: 519442:HUTA_RS09840
uniprot id: C7NTI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

519442:HUTA RS12650
gene id: 519442:HUTA_RS12650
uniprot id: C7NPI4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

519442:HUTA RS12170
gene id: 519442:HUTA_RS12170
uniprot id: C7NMU6
names: Subunit
messages: Tetramer of two components I and two components II.

519442:HUTA RS01240
gene id: 519442:HUTA_RS01240
uniprot id: C7NQI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

519442:HUTA RS10145
gene id: 519442:HUTA_RS10145
uniprot id: C7NTZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

519442:HUTA RS01575
gene id: 519442:HUTA_RS01575
uniprot id: C7NQQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

519442:HUTA RS12250
gene id: 519442:HUTA_RS12250
uniprot id: C7NMW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

519442:HUTA RS00635
gene id: 519442:HUTA_RS00635
uniprot id: C7NP28
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

519442:HUTA RS01545
gene id: 519442:HUTA_RS01545
uniprot id: C7NQP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS00940
gene id: 519442:HUTA_RS00940
uniprot id: C7NPT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

519442:HUTA RS03690
gene id: 519442:HUTA_RS03690
uniprot id: C7NTU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

519442:HUTA RS08895
gene id: 519442:HUTA_RS08895
uniprot id: C7NSA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

519442:HUTA RS08115
gene id: 519442:HUTA_RS08115
uniprot id: C7NQT2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

519442:HUTA RS10595
gene id: 519442:HUTA_RS10595
uniprot id: C7NUH7
names: Subcellular Location Annotation
messages: Nucleus

519442:HUTA RS11880
gene id: 519442:HUTA_RS11880
uniprot id: C7NMF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

519442:HUTA RS13515
gene id: 519442:HUTA_RS13515
uniprot id: C7NR06
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

519442:HUTA RS09690
gene id: 519442:HUTA_RS09690
uniprot id: C7NTF8
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS01490
gene id: 519442:HUTA_RS01490
uniprot id: C7NQN6
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

519442:HUTA RS12920
gene id: 519442:HUTA_RS12920
uniprot id: C7NML1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS09800
gene id: 519442:HUTA_RS09800
uniprot id: C7NTI0
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS02210
gene id: 519442:HUTA_RS02210
uniprot id: C7NS28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

519442:HUTA RS07185
gene id: 519442:HUTA_RS07185
uniprot id: C7NNX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

519442:HUTA RS04905
gene id: 519442:HUTA_RS04905
uniprot id: C7NVA0
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS04595
gene id: 519442:HUTA_RS04595
uniprot id: C7NUV8
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

519442:HUTA RS12700
gene id: 519442:HUTA_RS12700
uniprot id: C7NPJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519442:HUTA RS11365
gene id: 519442:HUTA_RS11365
uniprot id: C7NVG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

519442:HUTA RS08290
gene id: 519442:HUTA_RS08290
uniprot id: C7NQW6
names: Caution
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

519442:HUTA RS14400
gene id: 519442:HUTA_RS14400
uniprot id: C7NSI4
names: Similarity
messages: Belongs to the Nth/MutY family.

519442:HUTA RS04510
gene id: 519442:HUTA_RS04510
uniprot id: C7NUU1
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS10165
gene id: 519442:HUTA_RS10165
uniprot id: C7NTZ7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

519442:HUTA RS12680
gene id: 519442:HUTA_RS12680
uniprot id: C7NPJ0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

519442:HUTA RS11285
gene id: 519442:HUTA_RS11285
uniprot id: C7NV60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

519442:HUTA RS00975
gene id: 519442:HUTA_RS00975
uniprot id: C7NPU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

519442:HUTA RS13745
gene id: 519442:HUTA_RS13745
uniprot id: C7NR56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

519442:HUTA RS06920
gene id: 519442:HUTA_RS06920
uniprot id: C7NNR8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

519442:HUTA RS09035
gene id: 519442:HUTA_RS09035
uniprot id: C7NSD0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS04960
gene id: 519442:HUTA_RS04960
uniprot id: C7NVB1
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.

519442:HUTA RS02755
gene id: 519442:HUTA_RS02755
uniprot id: C7NST6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS14600
gene id: 519442:HUTA_RS14600
uniprot id: C7NSM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS05505
gene id: 519442:HUTA_RS05505
uniprot id: C7NM96
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS07290
gene id: 519442:HUTA_RS07290
uniprot id: C7NP82
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

519442:HUTA RS04420
gene id: 519442:HUTA_RS04420
uniprot id: C7NUS2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

519442:HUTA RS11670
gene id: 519442:HUTA_RS11670
uniprot id: C7NVM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

519442:HUTA RS06690
gene id: 519442:HUTA_RS06690
uniprot id: C7NNE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

519442:HUTA RS01265
gene id: 519442:HUTA_RS01265
uniprot id: C7NQI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

519442:HUTA RS11685
gene id: 519442:HUTA_RS11685
uniprot id: C7NVM9
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

519442:HUTA RS13360
gene id: 519442:HUTA_RS13360
uniprot id: C7NPP2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS12420
gene id: 519442:HUTA_RS12420
uniprot id: C7NMZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS13495
gene id: 519442:HUTA_RS13495
uniprot id: C7NR02
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

519442:HUTA RS12240
gene id: 519442:HUTA_RS12240
uniprot id: C7NMW0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

519442:HUTA RS09160
gene id: 519442:HUTA_RS09160
uniprot id: C7NSF6
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS04910
gene id: 519442:HUTA_RS04910
uniprot id: C7NVA1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

519442:HUTA RS10910
gene id: 519442:HUTA_RS10910
uniprot id: C7NUP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

519442:HUTA RS09920
gene id: 519442:HUTA_RS09920
uniprot id: C7NTK6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

519442:HUTA RS02760
gene id: 519442:HUTA_RS02760
uniprot id: C7NST7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS10900
gene id: 519442:HUTA_RS10900
uniprot id: C7NUN9
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

519442:HUTA RS06815
gene id: 519442:HUTA_RS06815
uniprot id: C7NNP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

519442:HUTA RS12945
gene id: 519442:HUTA_RS12945
uniprot id: C7NPN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

519442:HUTA RS03825
gene id: 519442:HUTA_RS03825
uniprot id: C7NTX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

519442:HUTA RS12670
gene id: 519442:HUTA_RS12670
uniprot id: C7NPI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

519442:HUTA RS03140
gene id: 519442:HUTA_RS03140
uniprot id: C7NTA5
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

519442:HUTA RS00900
gene id: 519442:HUTA_RS00900
uniprot id: C7NPS7
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

519442:HUTA RS14295
gene id: 519442:HUTA_RS14295
uniprot id: C7NR87
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS06035
gene id: 519442:HUTA_RS06035
uniprot id: C7NN13
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS13890
gene id: 519442:HUTA_RS13890
uniprot id: C7NQI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

519442:HUTA RS02395
gene id: 519442:HUTA_RS02395
uniprot id: C7NS66
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

519442:HUTA RS04385
gene id: 519442:HUTA_RS04385
uniprot id: C7NUR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

519442:HUTA RS12190
gene id: 519442:HUTA_RS12190
uniprot id: C7NMV0
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS05710
gene id: 519442:HUTA_RS05710
uniprot id: C7NMN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

519442:HUTA RS10715
gene id: 519442:HUTA_RS10715
uniprot id: C7NUK1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS08600
gene id: 519442:HUTA_RS08600
uniprot id: C7NRK0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

519442:HUTA RS08840
gene id: 519442:HUTA_RS08840
uniprot id: C7NRP4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

519442:HUTA RS01595
gene id: 519442:HUTA_RS01595
uniprot id: C7NQQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

519442:HUTA RS07005
gene id: 519442:HUTA_RS07005
uniprot id: C7NNT5
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

519442:HUTA RS01270
gene id: 519442:HUTA_RS01270
uniprot id: C7NQJ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS13120
gene id: 519442:HUTA_RS13120
uniprot id: C7NQB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

519442:HUTA RS13775
gene id: 519442:HUTA_RS13775
uniprot id: C7NR63
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS03460
gene id: 519442:HUTA_RS03460
uniprot id: C7NTQ4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

519442:HUTA RS00120
gene id: 519442:HUTA_RS00120
uniprot id: C7NNI5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

519442:HUTA RS14750
gene id: 519442:HUTA_RS14750
uniprot id: C7NRZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

519442:HUTA RS02125
gene id: 519442:HUTA_RS02125
uniprot id: C7NS11
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

519442:HUTA RS07220
gene id: 519442:HUTA_RS07220
uniprot id: C7NP67
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

519442:HUTA RS13570
gene id: 519442:HUTA_RS13570
uniprot id: C7NR17
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS10365
gene id: 519442:HUTA_RS10365
uniprot id: C7NU39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519442:HUTA RS11190
gene id: 519442:HUTA_RS11190
uniprot id: C7NV42
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

519442:HUTA RS08190
gene id: 519442:HUTA_RS08190
uniprot id: C7NQU9
names: Function
messages: Protects DNA against thermal denaturation and modulates transcription.

519442:HUTA RS06255
gene id: 519442:HUTA_RS06255
uniprot id: C7NN58
names: Similarity
messages: Belongs to the TrpF family.

519442:HUTA RS07010
gene id: 519442:HUTA_RS07010
uniprot id: C7NNT6
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

519442:HUTA RS07485
gene id: 519442:HUTA_RS07485
uniprot id: C7NPC3
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS00910
gene id: 519442:HUTA_RS00910
uniprot id: C7NPS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

519442:HUTA RS14000
gene id: 519442:HUTA_RS14000
uniprot id: C7NRR4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

519442:HUTA RS08110
gene id: 519442:HUTA_RS08110
uniprot id: C7NQT1
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS06580
gene id: 519442:HUTA_RS06580
uniprot id: C7NNC5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

519442:HUTA RS06435
gene id: 519442:HUTA_RS06435
uniprot id: C7NN96
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

519442:HUTA RS07550
gene id: 519442:HUTA_RS07550
uniprot id: C7NPD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

519442:HUTA RS12885
gene id: 519442:HUTA_RS12885
uniprot id: C7NPN3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

519442:HUTA RS07020
gene id: 519442:HUTA_RS07020
uniprot id: C7NNT8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

519442:HUTA RS02495
gene id: 519442:HUTA_RS02495
uniprot id: C7NS86
names: Similarity
messages: Belongs to the GARS family.

519442:HUTA RS07890
gene id: 519442:HUTA_RS07890
uniprot id: C7NQ49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

519442:HUTA RS07795
gene id: 519442:HUTA_RS07795
uniprot id: C7NQ29
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS03645
gene id: 519442:HUTA_RS03645
uniprot id: C7NTU0
names: Similarity
messages: Belongs to the cytochrome P450 family.

519442:HUTA RS14095
gene id: 519442:HUTA_RS14095
uniprot id: C7NRT4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

519442:HUTA RS12550
gene id: 519442:HUTA_RS12550
uniprot id: C7NPG5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

519442:HUTA RS04090
gene id: 519442:HUTA_RS04090
uniprot id: C7NUC3
names: Subcellular Location Annotation
messages: Cytoplasm

519442:HUTA RS03120
gene id: 519442:HUTA_RS03120
uniprot id: C7NTA1
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS07425
gene id: 519442:HUTA_RS07425
uniprot id: C7NPB1
names: Similarity
messages: Belongs to the citrate synthase family.

519442:HUTA RS07315
gene id: 519442:HUTA_RS07315
uniprot id: C7NP87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

519442:HUTA RS10755
gene id: 519442:HUTA_RS10755
uniprot id: C7NUK9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

519442:HUTA RS07865
gene id: 519442:HUTA_RS07865
uniprot id: C7NQ43
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

519442:HUTA RS02630
gene id: 519442:HUTA_RS02630
uniprot id: C7NSR0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

519442:HUTA RS04425
gene id: 519442:HUTA_RS04425
uniprot id: C7NUS3
names: Similarity
messages: Belongs to the LarC family.

519442:HUTA RS03775
gene id: 519442:HUTA_RS03775
uniprot id: C7NTW7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

519442:HUTA RS02540
gene id: 519442:HUTA_RS02540
uniprot id: C7NS95
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

519442:HUTA RS05585
gene id: 519442:HUTA_RS05585
uniprot id: C7NMB2
names: Similarity
messages: Belongs to the UPF0045 family.

519442:HUTA RS13055
gene id: 519442:HUTA_RS13055
uniprot id: C7NQ98
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

519442:HUTA RS11240
gene id: 519442:HUTA_RS11240
uniprot id: C7NV51
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

519442:HUTA RS13435
gene id: 519442:HUTA_RS13435
uniprot id: C7NQG1
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

519442:HUTA RS10700
gene id: 519442:HUTA_RS10700
uniprot id: C7NUJ8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

519442:HUTA RS01780
gene id: 519442:HUTA_RS01780
uniprot id: C7NRB6
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

519442:HUTA RS02160
gene id: 519442:HUTA_RS02160
uniprot id: C7NS18
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

519442:HUTA RS05715
gene id: 519442:HUTA_RS05715
uniprot id: C7NMN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

519442:HUTA RS05240
gene id: 519442:HUTA_RS05240
uniprot id: C7NM46
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS00735
gene id: 519442:HUTA_RS00735
uniprot id: C7NP49
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

519442:HUTA RS03675
gene id: 519442:HUTA_RS03675
uniprot id: C7NTU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

519442:HUTA RS07725
gene id: 519442:HUTA_RS07725
uniprot id: C7NQ15
names: Similarity
messages: Belongs to the UPF0145 family.

519442:HUTA RS02625
gene id: 519442:HUTA_RS02625
uniprot id: C7NSQ9
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

519442:HUTA RS00210
gene id: 519442:HUTA_RS00210
uniprot id: C7NNK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

519442:HUTA RS13980
gene id: 519442:HUTA_RS13980
uniprot id: C7NRR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

519442:HUTA RS04080
gene id: 519442:HUTA_RS04080
uniprot id: C7NUC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

519442:HUTA RS02450
gene id: 519442:HUTA_RS02450
uniprot id: C7NS77
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS03385
gene id: 519442:HUTA_RS03385
uniprot id: C7NTF5
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

519442:HUTA RS02665
gene id: 519442:HUTA_RS02665
uniprot id: C7NSR7
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 zinc ion.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

519442:HUTA RS07655
gene id: 519442:HUTA_RS07655
uniprot id: C7NQ02
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519442:HUTA RS04375
gene id: 519442:HUTA_RS04375
uniprot id: C7NUR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

519442:HUTA RS06145
gene id: 519442:HUTA_RS06145
uniprot id: C7NN36
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

519442:HUTA RS14325
gene id: 519442:HUTA_RS14325
uniprot id: C7NRX1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

519442:HUTA RS02775
gene id: 519442:HUTA_RS02775
uniprot id: C7NSU0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS08035
gene id: 519442:HUTA_RS08035
uniprot id: C7NQ78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

519442:HUTA RS03820
gene id: 519442:HUTA_RS03820
uniprot id: C7NTX5
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

519442:HUTA RS09765
gene id: 519442:HUTA_RS09765
uniprot id: C7NTH3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

519442:HUTA RS09805
gene id: 519442:HUTA_RS09805
uniprot id: C7NTI1
names: Similarity
messages: Belongs to the Dps family.

519442:HUTA RS07705
gene id: 519442:HUTA_RS07705
uniprot id: C7NQ11
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

519442:HUTA RS02565
gene id: 519442:HUTA_RS02565
uniprot id: C7NSA0
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

519442:HUTA RS14200
gene id: 519442:HUTA_RS14200
uniprot id: C7NRV5
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

519442:HUTA RS09170
gene id: 519442:HUTA_RS09170
uniprot id: C7NSF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519442:HUTA RS13715
gene id: 519442:HUTA_RS13715
uniprot id: C7NR50
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

519442:HUTA RS07015
gene id: 519442:HUTA_RS07015
uniprot id: C7NNT7
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

519442:HUTA RS04900
gene id: 519442:HUTA_RS04900
uniprot id: C7NV99
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

519442:HUTA RS10250
gene id: 519442:HUTA_RS10250
uniprot id: C7NU15
names: Similarity
messages: Belongs to the UPF0111 family.

519442:HUTA RS13635
gene id: 519442:HUTA_RS13635
uniprot id: C7NR32
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

519442:HUTA RS03090
gene id: 519442:HUTA_RS03090
uniprot id: C7NT95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

519442:HUTA RS11475
gene id: 519442:HUTA_RS11475
uniprot id: C7NVI7
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

519442:HUTA RS07720
gene id: 519442:HUTA_RS07720
uniprot id: C7NQ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

519442:HUTA RS09585
gene id: 519442:HUTA_RS09585
uniprot id: C7NT52
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519442:HUTA RS06585
gene id: 519442:HUTA_RS06585
uniprot id: C7NNC6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

519442:HUTA RS02065
gene id: 519442:HUTA_RS02065
uniprot id: C7NRZ9
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

519442:HUTA RS13135
gene id: 519442:HUTA_RS13135
uniprot id: C7NQB4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

519442:HUTA RS06300
gene id: 519442:HUTA_RS06300
uniprot id: C7NN68
names: Subcellular Location Annotation
messages: Membrane

519442:HUTA RS07765
gene id: 519442:HUTA_RS07765
uniprot id: C7NQ24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

519442:HUTA RS08715
gene id: 519442:HUTA_RS08715
uniprot id: C7NRM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

519442:HUTA RS08060
gene id: 519442:HUTA_RS08060
uniprot id: C7NQS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.