519441:SMON RS01595
gene id: 519441:SMON_RS01595
uniprot id: D1AWX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

519441:SMON RS05130
gene id: 519441:SMON_RS05130
uniprot id: D1AYV3
names: Similarity
messages: Belongs to the peptidase C40 family.

519441:SMON RS01325
gene id: 519441:SMON_RS01325
uniprot id: D1AWR6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

519441:SMON RS06195
gene id: 519441:SMON_RS06195
uniprot id: D1AVB0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

519441:SMON RS00880
gene id: 519441:SMON_RS00880
uniprot id: D1AWI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS05550
gene id: 519441:SMON_RS05550
uniprot id: D1AUZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

519441:SMON RS07395
gene id: 519441:SMON_RS07395
uniprot id: D1AVX4
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

519441:SMON RS05630
gene id: 519441:SMON_RS05630
uniprot id: D1AV12
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

519441:SMON RS01345
gene id: 519441:SMON_RS01345
uniprot id: D1AWS0
names: Subcellular Location Annotation
messages: Cytoplasm

519441:SMON RS02180
gene id: 519441:SMON_RS02180
uniprot id: D1AX84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS01950
gene id: 519441:SMON_RS01950
uniprot id: D1AX41
names: Similarity
messages: Belongs to the peptidase M18 family.

519441:SMON RS02010
gene id: 519441:SMON_RS02010
uniprot id: D1AX53
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

519441:SMON RS03860
gene id: 519441:SMON_RS03860
uniprot id: D1AY50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

519441:SMON RS04850
gene id: 519441:SMON_RS04850
uniprot id: D1AYP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

519441:SMON RS05990
gene id: 519441:SMON_RS05990
uniprot id: D1AV78
names: Similarity
messages: Belongs to the GSP E family.

519441:SMON RS00140
gene id: 519441:SMON_RS00140
uniprot id: D1AW51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS06760
gene id: 519441:SMON_RS06760
uniprot id: D1AVL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

519441:SMON RS07725
gene id: 519441:SMON_RS07725
uniprot id: D1AXQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS03620
gene id: 519441:SMON_RS03620
uniprot id: D1AY04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

519441:SMON RS07165
gene id: 519441:SMON_RS07165
uniprot id: D1AVT6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

519441:SMON RS06590
gene id: 519441:SMON_RS06590
uniprot id: D1AVI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS04930
gene id: 519441:SMON_RS04930
uniprot id: D1AYR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS07560
gene id: 519441:SMON_RS07560
uniprot id: D1AW09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS06865
gene id: 519441:SMON_RS06865
uniprot id: D1AVM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

519441:SMON RS04330
gene id: 519441:SMON_RS04330
uniprot id: D1AYE4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

519441:SMON RS03455
gene id: 519441:SMON_RS03455
uniprot id: D1AXX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

519441:SMON RS02345
gene id: 519441:SMON_RS02345
uniprot id: D1AXB4
names: Similarity
messages: Belongs to the leucine-binding protein family.

519441:SMON RS01635
gene id: 519441:SMON_RS01635
uniprot id: D1AWX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

519441:SMON RS03785
gene id: 519441:SMON_RS03785
uniprot id: D1AY36
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

519441:SMON RS00950
gene id: 519441:SMON_RS00950
uniprot id: D1AWK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

519441:SMON RS05300
gene id: 519441:SMON_RS05300
uniprot id: D1AUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS07335
gene id: 519441:SMON_RS07335
uniprot id: D1AVW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

519441:SMON RS08050
gene id: 519441:SMON_RS08050
uniprot id: D1AYN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

519441:SMON RS00130
gene id: 519441:SMON_RS00130
uniprot id: D1AW49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

519441:SMON RS07055
gene id: 519441:SMON_RS07055
uniprot id: D1AVR5
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS00585
gene id: 519441:SMON_RS00585
uniprot id: D1AWD4
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

519441:SMON RS06940
gene id: 519441:SMON_RS06940
uniprot id: D1AVP3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

519441:SMON RS07005
gene id: 519441:SMON_RS07005
uniprot id: D1AVQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

519441:SMON RS04070
gene id: 519441:SMON_RS04070
uniprot id: D1AY91
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS04160
gene id: 519441:SMON_RS04160
uniprot id: D1AYA9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

519441:SMON RS05260
gene id: 519441:SMON_RS05260
uniprot id: D1AUU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

519441:SMON RS04080
gene id: 519441:SMON_RS04080
uniprot id: D1AY93
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

519441:SMON RS06285
gene id: 519441:SMON_RS06285
uniprot id: D1AVC6
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

519441:SMON RS02540
gene id: 519441:SMON_RS02540
uniprot id: D1AXF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

519441:SMON RS06345
gene id: 519441:SMON_RS06345
uniprot id: D1AVD8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

519441:SMON RS00755
gene id: 519441:SMON_RS00755
uniprot id: D1AWG6
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS04355
gene id: 519441:SMON_RS04355
uniprot id: D1AYE9
names: Similarity
messages: Belongs to the PRORSD1 family.

519441:SMON RS02230
gene id: 519441:SMON_RS02230
uniprot id: D1AX89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

519441:SMON RS00065
gene id: 519441:SMON_RS00065
uniprot id: D1AW36
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

519441:SMON RS02130
gene id: 519441:SMON_RS02130
uniprot id: D1AX76
names: Similarity
messages: Belongs to the disproportionating enzyme family.

519441:SMON RS07525
gene id: 519441:SMON_RS07525
uniprot id: D1AW03
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS05505
gene id: 519441:SMON_RS05505
uniprot id: D1AUY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

519441:SMON RS04165
gene id: 519441:SMON_RS04165
uniprot id: D1AYB0
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS03570
gene id: 519441:SMON_RS03570
uniprot id: D1AXZ4
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS05895
gene id: 519441:SMON_RS05895
uniprot id: D1AV59
names: Similarity
messages: Belongs to the peptidase C40 family.

519441:SMON RS02470
gene id: 519441:SMON_RS02470
uniprot id: D1AXD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

519441:SMON RS04910
gene id: 519441:SMON_RS04910
uniprot id: D1AYR0
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS04305
gene id: 519441:SMON_RS04305
uniprot id: D1AYD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

519441:SMON RS02545
gene id: 519441:SMON_RS02545
uniprot id: D1AXF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

519441:SMON RS01995
gene id: 519441:SMON_RS01995
uniprot id: D1AX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

519441:SMON RS01510
gene id: 519441:SMON_RS01510
uniprot id: D1AWV3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

519441:SMON RS07180
gene id: 519441:SMON_RS07180
uniprot id: D1AVT8
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS03595
gene id: 519441:SMON_RS03595
uniprot id: D1AXZ9
names: Similarity
messages: Belongs to the TlyA family.

519441:SMON RS07090
gene id: 519441:SMON_RS07090
uniprot id: D1AVS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

519441:SMON RS06510
gene id: 519441:SMON_RS06510
uniprot id: D1AVH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

519441:SMON RS04005
gene id: 519441:SMON_RS04005
uniprot id: D1AY79
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

519441:SMON RS01120
gene id: 519441:SMON_RS01120
uniprot id: D1AWN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS00440
gene id: 519441:SMON_RS00440
uniprot id: D1AWA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

519441:SMON RS06200
gene id: 519441:SMON_RS06200
uniprot id: D1AVB1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

519441:SMON RS02120
gene id: 519441:SMON_RS02120
uniprot id: D1AX74
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

519441:SMON RS00760
gene id: 519441:SMON_RS00760
uniprot id: D1AWG7
names: Subcellular Location Annotation
messages: Cytoplasm

519441:SMON RS03965
gene id: 519441:SMON_RS03965
uniprot id: D1AY71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

519441:SMON RS02655
gene id: 519441:SMON_RS02655
uniprot id: D1AXH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

519441:SMON RS03205
gene id: 519441:SMON_RS03205
uniprot id: D1AXS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

519441:SMON RS02880
gene id: 519441:SMON_RS02880
uniprot id: D1AXL5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

519441:SMON RS04295
gene id: 519441:SMON_RS04295
uniprot id: D1AYD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

519441:SMON RS01460
gene id: 519441:SMON_RS01460
uniprot id: D1AWU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS01910
gene id: 519441:SMON_RS01910
uniprot id: D1AX34
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS01900
gene id: 519441:SMON_RS01900
uniprot id: D1AX32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

519441:SMON RS02555
gene id: 519441:SMON_RS02555
uniprot id: D1AXF3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

519441:SMON RS01245
gene id: 519441:SMON_RS01245
uniprot id: D1AWQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

519441:SMON RS04625
gene id: 519441:SMON_RS04625
uniprot id: D1AYK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519441:SMON RS03945
gene id: 519441:SMON_RS03945
uniprot id: D1AY67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

519441:SMON RS01740
gene id: 519441:SMON_RS01740
uniprot id: D1AWZ9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

519441:SMON RS06275
gene id: 519441:SMON_RS06275
uniprot id: D1AVC4
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

519441:SMON RS06160
gene id: 519441:SMON_RS06160
uniprot id: D1AVA3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS01915
gene id: 519441:SMON_RS01915
uniprot id: D1AX35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

519441:SMON RS01485
gene id: 519441:SMON_RS01485
uniprot id: D1AWU8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

519441:SMON RS03975
gene id: 519441:SMON_RS03975
uniprot id: D1AY73
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

519441:SMON RS06145
gene id: 519441:SMON_RS06145
uniprot id: D1AVA0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

519441:SMON RS00910
gene id: 519441:SMON_RS00910
uniprot id: D1AWJ5
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS02585
gene id: 519441:SMON_RS02585
uniprot id: D1AXF9
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS00445
gene id: 519441:SMON_RS00445
uniprot id: D1AWB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

519441:SMON RS03495
gene id: 519441:SMON_RS03495
uniprot id: D1AXX8
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS05345
gene id: 519441:SMON_RS05345
uniprot id: D1AUV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

519441:SMON RS05195
gene id: 519441:SMON_RS05195
uniprot id: D1AUS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

519441:SMON RS03175
gene id: 519441:SMON_RS03175
uniprot id: D1AXR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

519441:SMON RS01185
gene id: 519441:SMON_RS01185
uniprot id: D1AWP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

519441:SMON RS07465
gene id: 519441:SMON_RS07465
uniprot id: D1AVZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS00520
gene id: 519441:SMON_RS00520
uniprot id: D1AWC3
names: Similarity
messages: Belongs to the LOG family.

519441:SMON RS03065
gene id: 519441:SMON_RS03065
uniprot id: D1AXP8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

519441:SMON RS00785
gene id: 519441:SMON_RS00785
uniprot id: D1AWH2
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS02350
gene id: 519441:SMON_RS02350
uniprot id: D1AXB5
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS06000
gene id: 519441:SMON_RS06000
uniprot id: D1AV80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

519441:SMON RS04890
gene id: 519441:SMON_RS04890
uniprot id: D1AYQ7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

519441:SMON RS03970
gene id: 519441:SMON_RS03970
uniprot id: D1AY72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

519441:SMON RS06810
gene id: 519441:SMON_RS06810
uniprot id: D1AVL9
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

519441:SMON RS03465
gene id: 519441:SMON_RS03465
uniprot id: D1AXX2
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS07275
gene id: 519441:SMON_RS07275
uniprot id: D1AVV4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

519441:SMON RS01650
gene id: 519441:SMON_RS01650
uniprot id: D1AWY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

519441:SMON RS02415
gene id: 519441:SMON_RS02415
uniprot id: D1AXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

519441:SMON RS04140
gene id: 519441:SMON_RS04140
uniprot id: D1AYA5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

519441:SMON RS03185
gene id: 519441:SMON_RS03185
uniprot id: D1AXS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

519441:SMON RS01440
gene id: 519441:SMON_RS01440
uniprot id: D1AWT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

519441:SMON RS05245
gene id: 519441:SMON_RS05245
uniprot id: D1AUT9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

519441:SMON RS06460
gene id: 519441:SMON_RS06460
uniprot id: D1AVG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

519441:SMON RS04180
gene id: 519441:SMON_RS04180
uniprot id: D1AYB3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

519441:SMON RS06930
gene id: 519441:SMON_RS06930
uniprot id: D1AVP1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

519441:SMON RS04230
gene id: 519441:SMON_RS04230
uniprot id: D1AYC4
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS02815
gene id: 519441:SMON_RS02815
uniprot id: D1AXK3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

519441:SMON RS07530
gene id: 519441:SMON_RS07530
uniprot id: D1AW04
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

519441:SMON RS01625
gene id: 519441:SMON_RS01625
uniprot id: D1AWX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

519441:SMON RS02255
gene id: 519441:SMON_RS02255
uniprot id: D1AX95
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

519441:SMON RS02700
gene id: 519441:SMON_RS02700
uniprot id: D1AXI0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

519441:SMON RS01720
gene id: 519441:SMON_RS01720
uniprot id: D1AWZ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

519441:SMON RS06485
gene id: 519441:SMON_RS06485
uniprot id: D1AVG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

519441:SMON RS00715
gene id: 519441:SMON_RS00715
uniprot id: D1AWF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS04525
gene id: 519441:SMON_RS04525
uniprot id: D1AYI3
names: Similarity
messages: Belongs to the GSP E family.

519441:SMON RS00225
gene id: 519441:SMON_RS00225
uniprot id: D1AW68
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

519441:SMON RS03940
gene id: 519441:SMON_RS03940
uniprot id: D1AY66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

519441:SMON RS07350
gene id: 519441:SMON_RS07350
uniprot id: D1AVW5
names: Similarity
messages: Belongs to the GSP E family.

519441:SMON RS04245
gene id: 519441:SMON_RS04245
uniprot id: D1AYC7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

519441:SMON RS06890
gene id: 519441:SMON_RS06890
uniprot id: D1AVN3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

519441:SMON RS05800
gene id: 519441:SMON_RS05800
uniprot id: D1AV39
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

519441:SMON RS05040
gene id: 519441:SMON_RS05040
uniprot id: D1AYT6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS01610
gene id: 519441:SMON_RS01610
uniprot id: D1AWX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

519441:SMON RS00460
gene id: 519441:SMON_RS00460
uniprot id: D1AWB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

519441:SMON RS03280
gene id: 519441:SMON_RS03280
uniprot id: D1AXU0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

519441:SMON RS00435
gene id: 519441:SMON_RS00435
uniprot id: D1AWA8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

519441:SMON RS00945
gene id: 519441:SMON_RS00945
uniprot id: D1AWK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

519441:SMON RS03235
gene id: 519441:SMON_RS03235
uniprot id: D1AXT1
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

519441:SMON RS01945
gene id: 519441:SMON_RS01945
uniprot id: D1AX40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

519441:SMON RS01490
gene id: 519441:SMON_RS01490
uniprot id: D1AWU9
names: Similarity
messages: Belongs to the FBPase class 2 family.

519441:SMON RS05225
gene id: 519441:SMON_RS05225
uniprot id: D1AUT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

519441:SMON RS05780
gene id: 519441:SMON_RS05780
uniprot id: D1AV35
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS03245
gene id: 519441:SMON_RS03245
uniprot id: D1AXT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.

519441:SMON RS03560
gene id: 519441:SMON_RS03560
uniprot id: D1AXZ2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

519441:SMON RS04705
gene id: 519441:SMON_RS04705
uniprot id: D1AYM0
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS06990
gene id: 519441:SMON_RS06990
uniprot id: D1AVQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS03195
gene id: 519441:SMON_RS03195
uniprot id: D1AXS3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

519441:SMON RS00490
gene id: 519441:SMON_RS00490
uniprot id: D1AWB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

519441:SMON RS02090
gene id: 519441:SMON_RS02090
uniprot id: D1AX68
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS06540
gene id: 519441:SMON_RS06540
uniprot id: D1AVH8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

519441:SMON RS03100
gene id: 519441:SMON_RS03100
uniprot id: D1AXQ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS00005
gene id: 519441:SMON_RS00005
uniprot id: D1AW25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

519441:SMON RS06495
gene id: 519441:SMON_RS06495
uniprot id: D1AVG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

519441:SMON RS01200
gene id: 519441:SMON_RS01200
uniprot id: D1AWP7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS00905
gene id: 519441:SMON_RS00905
uniprot id: D1AWJ4
names: Similarity
messages: Belongs to the carbamate kinase family.

519441:SMON RS01315
gene id: 519441:SMON_RS01315
uniprot id: D1AWR4
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

519441:SMON RS00710
gene id: 519441:SMON_RS00710
uniprot id: D1AWF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS05030
gene id: 519441:SMON_RS05030
uniprot id: D1AYT4
names: Similarity
messages: Belongs to the DNase I family.

519441:SMON RS07535
gene id: 519441:SMON_RS07535
uniprot id: D1AW05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS05795
gene id: 519441:SMON_RS05795
uniprot id: D1AV38
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

519441:SMON RS07030
gene id: 519441:SMON_RS07030
uniprot id: D1AVR0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

519441:SMON RS07810
gene id: 519441:SMON_RS07810
uniprot id: D1AV81
names: Similarity
messages: Belongs to the TrbI/VirB10 family.

519441:SMON RS05380
gene id: 519441:SMON_RS05380
uniprot id: D1AUW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

519441:SMON RS02265
gene id: 519441:SMON_RS02265
uniprot id: D1AX97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

519441:SMON RS06385
gene id: 519441:SMON_RS06385
uniprot id: D1AVE7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

519441:SMON RS03950
gene id: 519441:SMON_RS03950
uniprot id: D1AY68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

519441:SMON RS01780
gene id: 519441:SMON_RS01780
uniprot id: D1AX07
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS02520
gene id: 519441:SMON_RS02520
uniprot id: D1AXE6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

519441:SMON RS02100
gene id: 519441:SMON_RS02100
uniprot id: D1AX70
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

519441:SMON RS00545
gene id: 519441:SMON_RS00545
uniprot id: D1AWC8
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

519441:SMON RS03300
gene id: 519441:SMON_RS03300
uniprot id: D1AXU4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

519441:SMON RS02000
gene id: 519441:SMON_RS02000
uniprot id: D1AX51
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

519441:SMON RS05830
gene id: 519441:SMON_RS05830
uniprot id: D1AV45
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS07070
gene id: 519441:SMON_RS07070
uniprot id: D1AVR8
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS01555
gene id: 519441:SMON_RS01555
uniprot id: D1AWW2
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS03545
gene id: 519441:SMON_RS03545
uniprot id: D1AXY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

519441:SMON RS04715
gene id: 519441:SMON_RS04715
uniprot id: D1AYM2
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS03575
gene id: 519441:SMON_RS03575
uniprot id: D1AXZ5
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS02565
gene id: 519441:SMON_RS02565
uniprot id: D1AXF5
names: Similarity
messages: Belongs to the peptidase S11 family.

519441:SMON RS02510
gene id: 519441:SMON_RS02510
uniprot id: D1AXE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

519441:SMON RS00900
gene id: 519441:SMON_RS00900
uniprot id: D1AWJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

519441:SMON RS04215
gene id: 519441:SMON_RS04215
uniprot id: D1AYC1
names: Similarity
messages: Belongs to the Dps family.

519441:SMON RS03265
gene id: 519441:SMON_RS03265
uniprot id: D1AXT7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

519441:SMON RS03380
gene id: 519441:SMON_RS03380
uniprot id: D1AXV6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

519441:SMON RS03255
gene id: 519441:SMON_RS03255
uniprot id: D1AXT5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

519441:SMON RS02175
gene id: 519441:SMON_RS02175
uniprot id: D1AX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS04310
gene id: 519441:SMON_RS04310
uniprot id: D1AYE0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

519441:SMON RS01955
gene id: 519441:SMON_RS01955
uniprot id: D1AX42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

519441:SMON RS06505
gene id: 519441:SMON_RS06505
uniprot id: D1AVH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

519441:SMON RS00550
gene id: 519441:SMON_RS00550
uniprot id: D1AWC9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

519441:SMON RS07120
gene id: 519441:SMON_RS07120
uniprot id: D1AVS8
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS01660
gene id: 519441:SMON_RS01660
uniprot id: D1AWY3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

519441:SMON RS02485
gene id: 519441:SMON_RS02485
uniprot id: D1AXD8
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

519441:SMON RS06140
gene id: 519441:SMON_RS06140
uniprot id: D1AV99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

519441:SMON RS01695
gene id: 519441:SMON_RS01695
uniprot id: D1AWZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

519441:SMON RS01495
gene id: 519441:SMON_RS01495
uniprot id: D1AWV0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

519441:SMON RS06445
gene id: 519441:SMON_RS06445
uniprot id: D1AVF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

519441:SMON RS05090
gene id: 519441:SMON_RS05090
uniprot id: D1AYU5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

519441:SMON RS07555
gene id: 519441:SMON_RS07555
uniprot id: D1AW08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS01620
gene id: 519441:SMON_RS01620
uniprot id: D1AWX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

519441:SMON RS02410
gene id: 519441:SMON_RS02410
uniprot id: D1AXC7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

519441:SMON RS05045
gene id: 519441:SMON_RS05045
uniprot id: D1AYT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS07115
gene id: 519441:SMON_RS07115
uniprot id: D1AVS7
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS03170
gene id: 519441:SMON_RS03170
uniprot id: D1AXR8
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

519441:SMON RS04270
gene id: 519441:SMON_RS04270
uniprot id: D1AYD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

519441:SMON RS02590
gene id: 519441:SMON_RS02590
uniprot id: D1AXG0
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS01285
gene id: 519441:SMON_RS01285
uniprot id: D1AWQ8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.

519441:SMON RS06625
gene id: 519441:SMON_RS06625
uniprot id: D1AVJ1
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS04645
gene id: 519441:SMON_RS04645
uniprot id: D1AYK8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

519441:SMON RS00385
gene id: 519441:SMON_RS00385
uniprot id: D1AWA0
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

519441:SMON RS06660
gene id: 519441:SMON_RS06660
uniprot id: D1AVJ7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

519441:SMON RS02940
gene id: 519441:SMON_RS02940
uniprot id: D1AXM4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

519441:SMON RS02970
gene id: 519441:SMON_RS02970
uniprot id: D1AXM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

519441:SMON RS00260
gene id: 519441:SMON_RS00260
uniprot id: D1AW75
names: Similarity
messages: Belongs to the GARS family.

519441:SMON RS00790
gene id: 519441:SMON_RS00790
uniprot id: D1AWH3
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS07290
gene id: 519441:SMON_RS07290
uniprot id: D1AVV7
names: Similarity
messages: Belongs to the peptidase S49 family.

519441:SMON RS05695
gene id: 519441:SMON_RS05695
uniprot id: D1AV22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

519441:SMON RS06450
gene id: 519441:SMON_RS06450
uniprot id: D1AVG0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

519441:SMON RS07485
gene id: 519441:SMON_RS07485
uniprot id: D1AVZ4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

519441:SMON RS07285
gene id: 519441:SMON_RS07285
uniprot id: D1AVV6
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS04155
gene id: 519441:SMON_RS04155
uniprot id: D1AYA8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

519441:SMON RS00375
gene id: 519441:SMON_RS00375
uniprot id: D1AW98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

519441:SMON RS03895
gene id: 519441:SMON_RS03895
uniprot id: D1AY57
names: Similarity
messages: Belongs to the ribF family.

519441:SMON RS06340
gene id: 519441:SMON_RS06340
uniprot id: D1AVD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

519441:SMON RS04025
gene id: 519441:SMON_RS04025
uniprot id: D1AY82
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

519441:SMON RS01465
gene id: 519441:SMON_RS01465
uniprot id: D1AWU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

519441:SMON RS03925
gene id: 519441:SMON_RS03925
uniprot id: D1AY63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

519441:SMON RS00310
gene id: 519441:SMON_RS00310
uniprot id: D1AW85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519441:SMON RS06475
gene id: 519441:SMON_RS06475
uniprot id: D1AVG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

519441:SMON RS00670
gene id: 519441:SMON_RS00670
uniprot id: D1AWF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

519441:SMON RS01715
gene id: 519441:SMON_RS01715
uniprot id: D1AWZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

519441:SMON RS01295
gene id: 519441:SMON_RS01295
uniprot id: D1AWR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

519441:SMON RS02705
gene id: 519441:SMON_RS02705
uniprot id: D1AXI1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

519441:SMON RS00470
gene id: 519441:SMON_RS00470
uniprot id: D1AWB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

519441:SMON RS04710
gene id: 519441:SMON_RS04710
uniprot id: D1AYM1
names: Similarity
messages: Belongs to the peptidase M16 family.

519441:SMON RS00290
gene id: 519441:SMON_RS00290
uniprot id: D1AW81
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

519441:SMON RS00625
gene id: 519441:SMON_RS00625
uniprot id: D1AWE2
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

519441:SMON RS06300
gene id: 519441:SMON_RS06300
uniprot id: D1AVC9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

519441:SMON RS02865
gene id: 519441:SMON_RS02865
uniprot id: D1AXL2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

519441:SMON RS03075
gene id: 519441:SMON_RS03075
uniprot id: D1AXQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519441:SMON RS02680
gene id: 519441:SMON_RS02680
uniprot id: D1AXH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

519441:SMON RS02395
gene id: 519441:SMON_RS02395
uniprot id: D1AXC4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

519441:SMON RS04765
gene id: 519441:SMON_RS04765
uniprot id: D1AYN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519441:SMON RS05340
gene id: 519441:SMON_RS05340
uniprot id: D1AUV6
names: Similarity
messages: Belongs to the RutC family.

519441:SMON RS04545
gene id: 519441:SMON_RS04545
uniprot id: D1AYI7
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

519441:SMON RS02020
gene id: 519441:SMON_RS02020
uniprot id: D1AX54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

519441:SMON RS05310
gene id: 519441:SMON_RS05310
uniprot id: D1AUV0
names: Similarity
messages: Belongs to the DapA family.

519441:SMON RS00605
gene id: 519441:SMON_RS00605
uniprot id: D1AWD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS06945
gene id: 519441:SMON_RS06945
uniprot id: D1AVP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

519441:SMON RS07445
gene id: 519441:SMON_RS07445
uniprot id: D1AVY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

519441:SMON RS00045
gene id: 519441:SMON_RS00045
uniprot id: D1AW33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS07605
gene id: 519441:SMON_RS07605
uniprot id: D1AW21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

519441:SMON RS01645
gene id: 519441:SMON_RS01645
uniprot id: D1AWY0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

519441:SMON RS03555
gene id: 519441:SMON_RS03555
uniprot id: D1AXZ1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

519441:SMON RS05515
gene id: 519441:SMON_RS05515
uniprot id: D1AUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

519441:SMON RS03985
gene id: 519441:SMON_RS03985
uniprot id: D1AY75
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

519441:SMON RS01735
gene id: 519441:SMON_RS01735
uniprot id: D1AWZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

519441:SMON RS01050
gene id: 519441:SMON_RS01050
uniprot id: D1AWM3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

519441:SMON RS07140
gene id: 519441:SMON_RS07140
uniprot id: D1AVT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

519441:SMON RS04470
gene id: 519441:SMON_RS04470
uniprot id: D1AYH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the VapD ribonuclease family.
messages: Cleaves ssRNA, mostly between U:A.
messages: Homodimer.

519441:SMON RS04400
gene id: 519441:SMON_RS04400
uniprot id: D1AYF7
names: Similarity
messages: Belongs to the type IA topoisomerase family.

519441:SMON RS00675
gene id: 519441:SMON_RS00675
uniprot id: D1AWF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

519441:SMON RS06520
gene id: 519441:SMON_RS06520
uniprot id: D1AVH4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

519441:SMON RS03835
gene id: 519441:SMON_RS03835
uniprot id: D1AY45
names: Similarity
messages: Belongs to the peptidase C40 family.

519441:SMON RS00850
gene id: 519441:SMON_RS00850
uniprot id: D1AWI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS00940
gene id: 519441:SMON_RS00940
uniprot id: D1AUV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

519441:SMON RS06800
gene id: 519441:SMON_RS06800
uniprot id: D1AVL7
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

519441:SMON RS03490
gene id: 519441:SMON_RS03490
uniprot id: D1AXX7
names: Similarity
messages: Belongs to the NAPRTase family.

519441:SMON RS00770
gene id: 519441:SMON_RS00770
uniprot id: D1AWG9
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS01500
gene id: 519441:SMON_RS01500
uniprot id: D1AWV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

519441:SMON RS04995
gene id: 519441:SMON_RS04995
uniprot id: D1AYS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS00865
gene id: 519441:SMON_RS00865
uniprot id: D1AWI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS03885
gene id: 519441:SMON_RS03885
uniprot id: D1AY55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

519441:SMON RS03905
gene id: 519441:SMON_RS03905
uniprot id: D1AY59
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

519441:SMON RS04090
gene id: 519441:SMON_RS04090
uniprot id: D1AY95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

519441:SMON RS05865
gene id: 519441:SMON_RS05865
uniprot id: D1AV51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class B bacterial acid phosphatase family.
messages: Homotetramer.
messages: Periplasm

519441:SMON RS06825
gene id: 519441:SMON_RS06825
uniprot id: D1AVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS01685
gene id: 519441:SMON_RS01685
uniprot id: D1AWY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

519441:SMON RS05555
gene id: 519441:SMON_RS05555
uniprot id: D1AUZ6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

519441:SMON RS05730
gene id: 519441:SMON_RS05730
uniprot id: D1AV29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

519441:SMON RS04980
gene id: 519441:SMON_RS04980
uniprot id: D1AYS4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

519441:SMON RS05525
gene id: 519441:SMON_RS05525
uniprot id: D1AUZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

519441:SMON RS02045
gene id: 519441:SMON_RS02045
uniprot id: D1AX59
names: Similarity
messages: Belongs to the peptidase S11 family.

519441:SMON RS03625
gene id: 519441:SMON_RS03625
uniprot id: D1AY05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

519441:SMON RS03060
gene id: 519441:SMON_RS03060
uniprot id: D1AXP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

519441:SMON RS03165
gene id: 519441:SMON_RS03165
uniprot id: D1AXR7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

519441:SMON RS01145
gene id: 519441:SMON_RS01145
uniprot id: D1AWP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

519441:SMON RS04805
gene id: 519441:SMON_RS04805
uniprot id: D1AYP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

519441:SMON RS00190
gene id: 519441:SMON_RS00190
uniprot id: D1AW61
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS05370
gene id: 519441:SMON_RS05370
uniprot id: D1AUW2
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

519441:SMON RS06655
gene id: 519441:SMON_RS06655
uniprot id: D1AVJ6
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

519441:SMON RS04490
gene id: 519441:SMON_RS04490
uniprot id: D1AYH5
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

519441:SMON RS02050
gene id: 519441:SMON_RS02050
uniprot id: D1AX60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

519441:SMON RS07360
gene id: 519441:SMON_RS07360
uniprot id: D1AVW7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS01380
gene id: 519441:SMON_RS01380
uniprot id: D1AWS7
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

519441:SMON RS05460
gene id: 519441:SMON_RS05460
uniprot id: D1AUX7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

519441:SMON RS00145
gene id: 519441:SMON_RS00145
uniprot id: D1AW52
names: Similarity
messages: Belongs to the peptidase C15 family.

519441:SMON RS03480
gene id: 519441:SMON_RS03480
uniprot id: D1AXX5
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS06525
gene id: 519441:SMON_RS06525
uniprot id: D1AVH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

519441:SMON RS01615
gene id: 519441:SMON_RS01615
uniprot id: D1AWX4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

519441:SMON RS00925
gene id: 519441:SMON_RS00925
uniprot id: D1AWJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

519441:SMON RS01370
gene id: 519441:SMON_RS01370
uniprot id: D1AWS5
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS05205
gene id: 519441:SMON_RS05205
uniprot id: D1AUT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

519441:SMON RS05050
gene id: 519441:SMON_RS05050
uniprot id: D1AYT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

519441:SMON RS06980
gene id: 519441:SMON_RS06980
uniprot id: D1AVQ0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

519441:SMON RS05155
gene id: 519441:SMON_RS05155
uniprot id: D1AYV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

519441:SMON RS05540
gene id: 519441:SMON_RS05540
uniprot id: D1AUZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

519441:SMON RS06565
gene id: 519441:SMON_RS06565
uniprot id: D1AVI3
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

519441:SMON RS00450
gene id: 519441:SMON_RS00450
uniprot id: D1AWB1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

519441:SMON RS03640
gene id: 519441:SMON_RS03640
uniprot id: D1AY08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

519441:SMON RS06910
gene id: 519441:SMON_RS06910
uniprot id: D1AVN7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

519441:SMON RS00965
gene id: 519441:SMON_RS00965
uniprot id: D1AWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

519441:SMON RS03230
gene id: 519441:SMON_RS03230
uniprot id: D1AXT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

519441:SMON RS04130
gene id: 519441:SMON_RS04130
uniprot id: D1AYA3
names: Similarity
messages: Belongs to the thioredoxin family.

519441:SMON RS04810
gene id: 519441:SMON_RS04810
uniprot id: D1AYP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

519441:SMON RS04150
gene id: 519441:SMON_RS04150
uniprot id: D1AYA7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

519441:SMON RS01960
gene id: 519441:SMON_RS01960
uniprot id: D1AX43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS01885
gene id: 519441:SMON_RS01885
uniprot id: D1AX29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

519441:SMON RS06675
gene id: 519441:SMON_RS06675
uniprot id: D1AVK0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

519441:SMON RS01055
gene id: 519441:SMON_RS01055
uniprot id: D1AWM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

519441:SMON RS06915
gene id: 519441:SMON_RS06915
uniprot id: D1AVN8
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS04690
gene id: 519441:SMON_RS04690
uniprot id: D1AYL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS03615
gene id: 519441:SMON_RS03615
uniprot id: D1AY03
names: Similarity
messages: Belongs to the DEAD box helicase family.

519441:SMON RS00750
gene id: 519441:SMON_RS00750
uniprot id: D1AWG5
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS00305
gene id: 519441:SMON_RS00305
uniprot id: D1AW84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519441:SMON RS01725
gene id: 519441:SMON_RS01725
uniprot id: D1AWZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

519441:SMON RS03600
gene id: 519441:SMON_RS03600
uniprot id: D1AY00
names: Similarity
messages: Belongs to the peptidase S41A family.

519441:SMON RS03190
gene id: 519441:SMON_RS03190
uniprot id: D1AXS2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

519441:SMON RS03990
gene id: 519441:SMON_RS03990
uniprot id: D1AY76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

519441:SMON RS02115
gene id: 519441:SMON_RS02115
uniprot id: D1AX73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

519441:SMON RS00930
gene id: 519441:SMON_RS00930
uniprot id: D1AWJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

519441:SMON RS00630
gene id: 519441:SMON_RS00630
uniprot id: D1AWE3
names: Similarity
messages: Belongs to the sulfatase family.

519441:SMON RS04555
gene id: 519441:SMON_RS04555
uniprot id: D1AYI9
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS00390
gene id: 519441:SMON_RS00390
uniprot id: D1AWA1
names: Similarity
messages: Belongs to the RecJ family.

519441:SMON RS02830
gene id: 519441:SMON_RS02830
uniprot id: D1AXK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

519441:SMON RS01665
gene id: 519441:SMON_RS01665
uniprot id: D1AWY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

519441:SMON RS06260
gene id: 519441:SMON_RS06260
uniprot id: D1AVC1
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS06835
gene id: 519441:SMON_RS06835
uniprot id: D1AVM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

519441:SMON RS02760
gene id: 519441:SMON_RS02760
uniprot id: D1AXJ2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

519441:SMON RS04075
gene id: 519441:SMON_RS04075
uniprot id: D1AY92
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

519441:SMON RS03675
gene id: 519441:SMON_RS03675
uniprot id: D1AY15
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

519441:SMON RS06790
gene id: 519441:SMON_RS06790
uniprot id: D1AVL5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

519441:SMON RS00975
gene id: 519441:SMON_RS00975
uniprot id: D1AWK8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

519441:SMON RS02780
gene id: 519441:SMON_RS02780
uniprot id: D1AXJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

519441:SMON RS03665
gene id: 519441:SMON_RS03665
uniprot id: D1AY13
names: Function
names: Similarity
messages: Belongs to the type-2 OGG1 family.
messages: Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).

519441:SMON RS05415
gene id: 519441:SMON_RS05415
uniprot id: D1AUW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS00105
gene id: 519441:SMON_RS00105
uniprot id: D1AW44
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS03960
gene id: 519441:SMON_RS03960
uniprot id: D1AY70
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

519441:SMON RS03030
gene id: 519441:SMON_RS03030
uniprot id: D1AXP1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

519441:SMON RS03690
gene id: 519441:SMON_RS03690
uniprot id: D1AY18
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

519441:SMON RS05715
gene id: 519441:SMON_RS05715
uniprot id: D1AV26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

519441:SMON RS06870
gene id: 519441:SMON_RS06870
uniprot id: D1AVM9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

519441:SMON RS03270
gene id: 519441:SMON_RS03270
uniprot id: D1AXT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS05190
gene id: 519441:SMON_RS05190
uniprot id: D1AUS8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

519441:SMON RS00325
gene id: 519441:SMON_RS00325
uniprot id: D1AW88
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

519441:SMON RS00480
gene id: 519441:SMON_RS00480
uniprot id: D1AWB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS01520
gene id: 519441:SMON_RS01520
uniprot id: D1AWV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

519441:SMON RS01015
gene id: 519441:SMON_RS01015
uniprot id: D1AWL6
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS01540
gene id: 519441:SMON_RS01540
uniprot id: D1AWV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS01415
gene id: 519441:SMON_RS01415
uniprot id: D1AWT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

519441:SMON RS04040
gene id: 519441:SMON_RS04040
uniprot id: D1AY85
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

519441:SMON RS02980
gene id: 519441:SMON_RS02980
uniprot id: D1AXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

519441:SMON RS06950
gene id: 519441:SMON_RS06950
uniprot id: D1AVP5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

519441:SMON RS01730
gene id: 519441:SMON_RS01730
uniprot id: D1AWZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

519441:SMON RS04350
gene id: 519441:SMON_RS04350
uniprot id: D1AYE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

519441:SMON RS06390
gene id: 519441:SMON_RS06390
uniprot id: D1AVE8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

519441:SMON RS07520
gene id: 519441:SMON_RS07520
uniprot id: D1AW02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

519441:SMON RS00235
gene id: 519441:SMON_RS00235
uniprot id: D1AW70
names: Similarity
messages: Belongs to the SAICAR synthetase family.

519441:SMON RS04960
gene id: 519441:SMON_RS04960
uniprot id: D1AYS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

519441:SMON RS05615
gene id: 519441:SMON_RS05615
uniprot id: D1AV09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

519441:SMON RS05200
gene id: 519441:SMON_RS05200
uniprot id: D1AUT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

519441:SMON RS00595
gene id: 519441:SMON_RS00595
uniprot id: D1AWD6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

519441:SMON RS00155
gene id: 519441:SMON_RS00155
uniprot id: D1AW55
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS06040
gene id: 519441:SMON_RS06040
uniprot id: D1AV88
names: Similarity
messages: Belongs to the MobA/MobL family.

519441:SMON RS00960
gene id: 519441:SMON_RS00960
uniprot id: D1AWK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

519441:SMON RS02490
gene id: 519441:SMON_RS02490
uniprot id: D1AXD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

519441:SMON RS05660
gene id: 519441:SMON_RS05660
uniprot id: D1AV18
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

519441:SMON RS00040
gene id: 519441:SMON_RS00040
uniprot id: D1AW32
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

519441:SMON RS06490
gene id: 519441:SMON_RS06490
uniprot id: D1AVG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

519441:SMON RS01445
gene id: 519441:SMON_RS01445
uniprot id: D1AWU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS05420
gene id: 519441:SMON_RS05420
uniprot id: D1AUX0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

519441:SMON RS04335
gene id: 519441:SMON_RS04335
uniprot id: D1AYE5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS05465
gene id: 519441:SMON_RS05465
uniprot id: D1AUX8
names: Similarity
messages: Belongs to the IMPACT family.

519441:SMON RS02695
gene id: 519441:SMON_RS02695
uniprot id: D1AXH9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

519441:SMON RS04725
gene id: 519441:SMON_RS04725
uniprot id: D1AYM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

519441:SMON RS03880
gene id: 519441:SMON_RS03880
uniprot id: D1AY54
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

519441:SMON RS02355
gene id: 519441:SMON_RS02355
uniprot id: D1AXB6
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS00860
gene id: 519441:SMON_RS00860
uniprot id: D1AWI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS07765
gene id: 519441:SMON_RS07765
uniprot id: D1AYI6
names: Similarity
messages: Belongs to the TrbI/VirB10 family.

519441:SMON RS01535
gene id: 519441:SMON_RS01535
uniprot id: D1AWV8
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

519441:SMON RS02575
gene id: 519441:SMON_RS02575
uniprot id: D1AXF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

519441:SMON RS03710
gene id: 519441:SMON_RS03710
uniprot id: D1AY22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

519441:SMON RS00610
gene id: 519441:SMON_RS00610
uniprot id: D1AWD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS07390
gene id: 519441:SMON_RS07390
uniprot id: D1AVX3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

519441:SMON RS00085
gene id: 519441:SMON_RS00085
uniprot id: D1AW40
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

519441:SMON RS05385
gene id: 519441:SMON_RS05385
uniprot id: D1AUW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

519441:SMON RS02605
gene id: 519441:SMON_RS02605
uniprot id: D1AXG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

519441:SMON RS04790
gene id: 519441:SMON_RS04790
uniprot id: D1AYN7
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

519441:SMON RS01405
gene id: 519441:SMON_RS01405
uniprot id: D1AWT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

519441:SMON RS01480
gene id: 519441:SMON_RS01480
uniprot id: D1AWU7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

519441:SMON RS00695
gene id: 519441:SMON_RS00695
uniprot id: D1AWF5
names: Similarity
messages: Belongs to the aldolase LacD family.

519441:SMON RS04265
gene id: 519441:SMON_RS04265
uniprot id: D1AYD1
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

519441:SMON RS04835
gene id: 519441:SMON_RS04835
uniprot id: D1AYP6
names: Similarity
messages: Belongs to the UPF0246 family.

519441:SMON RS05590
gene id: 519441:SMON_RS05590
uniprot id: D1AV04
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

519441:SMON RS02775
gene id: 519441:SMON_RS02775
uniprot id: D1AXJ5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

519441:SMON RS06765
gene id: 519441:SMON_RS06765
uniprot id: D1AVL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

519441:SMON RS03855
gene id: 519441:SMON_RS03855
uniprot id: D1AY49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

519441:SMON RS04820
gene id: 519441:SMON_RS04820
uniprot id: D1AYP3
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS00330
gene id: 519441:SMON_RS00330
uniprot id: D1AW89
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS03820
gene id: 519441:SMON_RS03820
uniprot id: D1AY42
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS03900
gene id: 519441:SMON_RS03900
uniprot id: D1AY58
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

519441:SMON RS03780
gene id: 519441:SMON_RS03780
uniprot id: D1AY35
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

519441:SMON RS02840
gene id: 519441:SMON_RS02840
uniprot id: D1AXK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

519441:SMON RS03250
gene id: 519441:SMON_RS03250
uniprot id: D1AXT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

519441:SMON RS06515
gene id: 519441:SMON_RS06515
uniprot id: D1AVH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

519441:SMON RS02480
gene id: 519441:SMON_RS02480
uniprot id: D1AXD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

519441:SMON RS00200
gene id: 519441:SMON_RS00200
uniprot id: D1AW63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

519441:SMON RS05785
gene id: 519441:SMON_RS05785
uniprot id: D1AV36
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

519441:SMON RS01060
gene id: 519441:SMON_RS01060
uniprot id: D1AWM5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS06465
gene id: 519441:SMON_RS06465
uniprot id: D1AVG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

519441:SMON RS04685
gene id: 519441:SMON_RS04685
uniprot id: D1AYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS01965
gene id: 519441:SMON_RS01965
uniprot id: D1AX44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS00355
gene id: 519441:SMON_RS00355
uniprot id: D1AW94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

519441:SMON RS02025
gene id: 519441:SMON_RS02025
uniprot id: D1AX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

519441:SMON RS04795
gene id: 519441:SMON_RS04795
uniprot id: D1AYN8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

519441:SMON RS03660
gene id: 519441:SMON_RS03660
uniprot id: D1AY12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

519441:SMON RS06190
gene id: 519441:SMON_RS06190
uniprot id: D1AVA9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

519441:SMON RS02925
gene id: 519441:SMON_RS02925
uniprot id: D1AXM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

519441:SMON RS05960
gene id: 519441:SMON_RS05960
uniprot id: D1AV72
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

519441:SMON RS00250
gene id: 519441:SMON_RS00250
uniprot id: D1AW73
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS03910
gene id: 519441:SMON_RS03910
uniprot id: D1AY60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

519441:SMON RS00135
gene id: 519441:SMON_RS00135
uniprot id: D1AW50
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS06855
gene id: 519441:SMON_RS06855
uniprot id: D1AVM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS01680
gene id: 519441:SMON_RS01680
uniprot id: D1AWY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

519441:SMON RS03445
gene id: 519441:SMON_RS03445
uniprot id: D1AXW8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

519441:SMON RS00095
gene id: 519441:SMON_RS00095
uniprot id: D1AW42
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

519441:SMON RS01895
gene id: 519441:SMON_RS01895
uniprot id: D1AX31
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

519441:SMON RS00995
gene id: 519441:SMON_RS00995
uniprot id: D1AWL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

519441:SMON RS01300
gene id: 519441:SMON_RS01300
uniprot id: D1AWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

519441:SMON RS05100
gene id: 519441:SMON_RS05100
uniprot id: D1AYU7
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

519441:SMON RS01690
gene id: 519441:SMON_RS01690
uniprot id: D1AWY9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

519441:SMON RS04065
gene id: 519441:SMON_RS04065
uniprot id: D1AY90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

519441:SMON RS03845
gene id: 519441:SMON_RS03845
uniprot id: D1AY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

519441:SMON RS01990
gene id: 519441:SMON_RS01990
uniprot id: D1AX49
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS02425
gene id: 519441:SMON_RS02425
uniprot id: D1AXD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS00465
gene id: 519441:SMON_RS00465
uniprot id: D1AWB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

519441:SMON RS00885
gene id: 519441:SMON_RS00885
uniprot id: D1AWJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS02965
gene id: 519441:SMON_RS02965
uniprot id: D1AXM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

519441:SMON RS03790
gene id: 519441:SMON_RS03790
uniprot id: D1AY37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

519441:SMON RS06355
gene id: 519441:SMON_RS06355
uniprot id: D1AVE0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

519441:SMON RS00370
gene id: 519441:SMON_RS00370
uniprot id: D1AW97
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

519441:SMON RS03695
gene id: 519441:SMON_RS03695
uniprot id: D1AY19
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

519441:SMON RS07600
gene id: 519441:SMON_RS07600
uniprot id: D1AW20
names: Similarity
messages: Belongs to the UPF0237 family.

519441:SMON RS03225
gene id: 519441:SMON_RS03225
uniprot id: D1AXS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

519441:SMON RS04640
gene id: 519441:SMON_RS04640
uniprot id: D1AYK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

519441:SMON RS01135
gene id: 519441:SMON_RS01135
uniprot id: D1AWP0
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS02475
gene id: 519441:SMON_RS02475
uniprot id: D1AXD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

519441:SMON RS05710
gene id: 519441:SMON_RS05710
uniprot id: D1AV25
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

519441:SMON RS07540
gene id: 519441:SMON_RS07540
uniprot id: D1AW06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS01110
gene id: 519441:SMON_RS01110
uniprot id: D1AWN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

519441:SMON RS02890
gene id: 519441:SMON_RS02890
uniprot id: D1AXL7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS03145
gene id: 519441:SMON_RS03145
uniprot id: D1AXR3
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

519441:SMON RS02725
gene id: 519441:SMON_RS02725
uniprot id: D1AXI5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

519441:SMON RS05035
gene id: 519441:SMON_RS05035
uniprot id: D1AYT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

519441:SMON RS02465
gene id: 519441:SMON_RS02465
uniprot id: D1AXD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

519441:SMON RS03760
gene id: 519441:SMON_RS03760
uniprot id: D1AY31
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

519441:SMON RS05065
gene id: 519441:SMON_RS05065
uniprot id: D1AYU1
names: Similarity
messages: Belongs to the aspartokinase family.

519441:SMON RS02215
gene id: 519441:SMON_RS02215
uniprot id: D1AX86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

519441:SMON RS05665
gene id: 519441:SMON_RS05665
uniprot id: D1AV19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

519441:SMON RS02785
gene id: 519441:SMON_RS02785
uniprot id: D1AXJ7
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS06500
gene id: 519441:SMON_RS06500
uniprot id: D1AVH0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

519441:SMON RS03220
gene id: 519441:SMON_RS03220
uniprot id: D1AXS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS04650
gene id: 519441:SMON_RS04650
uniprot id: D1AYK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

519441:SMON RS07460
gene id: 519441:SMON_RS07460
uniprot id: D1AVY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

519441:SMON RS00110
gene id: 519441:SMON_RS00110
uniprot id: D1AW45
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

519441:SMON RS01070
gene id: 519441:SMON_RS01070
uniprot id: D1AWM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS04020
gene id: 519441:SMON_RS04020
uniprot id: D1AY81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

519441:SMON RS01835
gene id: 519441:SMON_RS01835
uniprot id: D1AX19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS04170
gene id: 519441:SMON_RS04170
uniprot id: D1AYB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

519441:SMON RS00125
gene id: 519441:SMON_RS00125
uniprot id: D1AW48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

519441:SMON RS02600
gene id: 519441:SMON_RS02600
uniprot id: D1AXG2
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

519441:SMON RS03305
gene id: 519441:SMON_RS03305
uniprot id: D1AXU5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

519441:SMON RS03670
gene id: 519441:SMON_RS03670
uniprot id: D1AY14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

519441:SMON RS05215
gene id: 519441:SMON_RS05215
uniprot id: D1AUT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

519441:SMON RS00010
gene id: 519441:SMON_RS00010
uniprot id: D1AW26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

519441:SMON RS07170
gene id: 519441:SMON_RS07170
uniprot id: D1AVT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS06335
gene id: 519441:SMON_RS06335
uniprot id: D1AVD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS02460
gene id: 519441:SMON_RS02460
uniprot id: D1AXD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

519441:SMON RS07230
gene id: 519441:SMON_RS07230
uniprot id: D1AVU6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

519441:SMON RS01095
gene id: 519441:SMON_RS01095
uniprot id: D1AWN2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

519441:SMON RS05390
gene id: 519441:SMON_RS05390
uniprot id: D1AUW6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

519441:SMON RS02610
gene id: 519441:SMON_RS02610
uniprot id: D1AXG4
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

519441:SMON RS03260
gene id: 519441:SMON_RS03260
uniprot id: D1AXT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

519441:SMON RS01410
gene id: 519441:SMON_RS01410
uniprot id: D1AWT3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

519441:SMON RS00455
gene id: 519441:SMON_RS00455
uniprot id: D1AWB2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

519441:SMON RS00245
gene id: 519441:SMON_RS00245
uniprot id: D1AW72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

519441:SMON RS01865
gene id: 519441:SMON_RS01865
uniprot id: D1AX25
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

519441:SMON RS07130
gene id: 519441:SMON_RS07130
uniprot id: D1AVS9
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS03635
gene id: 519441:SMON_RS03635
uniprot id: D1AY07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

519441:SMON RS02595
gene id: 519441:SMON_RS02595
uniprot id: D1AXG1
names: Similarity
messages: Belongs to the BMP lipoprotein family.

519441:SMON RS05000
gene id: 519441:SMON_RS05000
uniprot id: D1AYS8
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

519441:SMON RS06415
gene id: 519441:SMON_RS06415
uniprot id: D1AVF3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

519441:SMON RS05210
gene id: 519441:SMON_RS05210
uniprot id: D1AUT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

519441:SMON RS05335
gene id: 519441:SMON_RS05335
uniprot id: D1AUV5
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

519441:SMON RS04050
gene id: 519441:SMON_RS04050
uniprot id: D1AY87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

519441:SMON RS01640
gene id: 519441:SMON_RS01640
uniprot id: D1AWX9
names: Similarity
messages: Belongs to the aldose epimerase family.

519441:SMON RS04565
gene id: 519441:SMON_RS04565
uniprot id: D1AYJ1
names: Similarity
messages: Belongs to the MobA/MobL family.

519441:SMON RS02625
gene id: 519441:SMON_RS02625
uniprot id: D1AXG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

519441:SMON RS04720
gene id: 519441:SMON_RS04720
uniprot id: D1AYM3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

519441:SMON RS06020
gene id: 519441:SMON_RS06020
uniprot id: D1AV85
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS05605
gene id: 519441:SMON_RS05605
uniprot id: D1AV07
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS04780
gene id: 519441:SMON_RS04780
uniprot id: D1AYN5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

519441:SMON RS03915
gene id: 519441:SMON_RS03915
uniprot id: D1AY61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

519441:SMON RS01330
gene id: 519441:SMON_RS01330
uniprot id: D1AWR7
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

519441:SMON RS04855
gene id: 519441:SMON_RS04855
uniprot id: D1AYQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

519441:SMON RS04425
gene id: 519441:SMON_RS04425
uniprot id: D1AYG2
names: Similarity
messages: Belongs to the peptidase C40 family.

519441:SMON RS01700
gene id: 519441:SMON_RS01700
uniprot id: D1AWZ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

519441:SMON RS05810
gene id: 519441:SMON_RS05810
uniprot id: D1AV41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

519441:SMON RS06750
gene id: 519441:SMON_RS06750
uniprot id: D1AVL1
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS06730
gene id: 519441:SMON_RS06730
uniprot id: D1AVK7
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

519441:SMON RS06400
gene id: 519441:SMON_RS06400
uniprot id: D1AVF0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

519441:SMON RS03285
gene id: 519441:SMON_RS03285
uniprot id: D1AXU1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

519441:SMON RS03015
gene id: 519441:SMON_RS03015
uniprot id: D1AXN8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

519441:SMON RS00890
gene id: 519441:SMON_RS00890
uniprot id: D1AWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS05295
gene id: 519441:SMON_RS05295
uniprot id: D1AUU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

519441:SMON RS02260
gene id: 519441:SMON_RS02260
uniprot id: D1AX96
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

519441:SMON RS04655
gene id: 519441:SMON_RS04655
uniprot id: D1AYL0
names: Similarity
messages: Belongs to the ArsC family.

519441:SMON RS06995
gene id: 519441:SMON_RS06995
uniprot id: D1AVQ3
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

519441:SMON RS00915
gene id: 519441:SMON_RS00915
uniprot id: D1AWJ6
names: Similarity
messages: Belongs to the peptidase C69 family.

519441:SMON RS06470
gene id: 519441:SMON_RS06470
uniprot id: D1AVG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

519441:SMON RS01065
gene id: 519441:SMON_RS01065
uniprot id: D1AWM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

519441:SMON RS04875
gene id: 519441:SMON_RS04875
uniprot id: D1AYQ4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

519441:SMON RS05670
gene id: 519441:SMON_RS05670
uniprot id: D1AV20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

519441:SMON RS03995
gene id: 519441:SMON_RS03995
uniprot id: D1AY77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

519441:SMON RS07610
gene id: 519441:SMON_RS07610
uniprot id: D1AW22
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

519441:SMON RS00935
gene id: 519441:SMON_RS00935
uniprot id: D1AWK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

519441:SMON RS08110
gene id: 519441:SMON_RS08110
uniprot id: D1AXH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

519441:SMON RS04660
gene id: 519441:SMON_RS04660
uniprot id: D1AYL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

519441:SMON RS05220
gene id: 519441:SMON_RS05220
uniprot id: D1AUT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

519441:SMON RS01175
gene id: 519441:SMON_RS01175
uniprot id: D1AWP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

519441:SMON RS05545
gene id: 519441:SMON_RS05545
uniprot id: D1AUZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

519441:SMON RS06440
gene id: 519441:SMON_RS06440
uniprot id: D1AVF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

519441:SMON RS07210
gene id: 519441:SMON_RS07210
uniprot id: D1AVU4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

519441:SMON RS02735
gene id: 519441:SMON_RS02735
uniprot id: D1AXI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

519441:SMON RS03745
gene id: 519441:SMON_RS03745
uniprot id: D1AY29
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS04015
gene id: 519441:SMON_RS04015
uniprot id: D1AY80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

519441:SMON RS01350
gene id: 519441:SMON_RS01350
uniprot id: D1AWS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

519441:SMON RS03385
gene id: 519441:SMON_RS03385
uniprot id: D1AXV7
names: Similarity
messages: Belongs to the HsdR family.

519441:SMON RS04630
gene id: 519441:SMON_RS04630
uniprot id: D1AYK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

519441:SMON RS05600
gene id: 519441:SMON_RS05600
uniprot id: D1AV06
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS02560
gene id: 519441:SMON_RS02560
uniprot id: D1AXF4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

519441:SMON RS05575
gene id: 519441:SMON_RS05575
uniprot id: D1AV01
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

519441:SMON RS02515
gene id: 519441:SMON_RS02515
uniprot id: D1AXE5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

519441:SMON RS07495
gene id: 519441:SMON_RS07495
uniprot id: D1AVZ6
names: Similarity
messages: Belongs to the asp23 family.

519441:SMON RS01805
gene id: 519441:SMON_RS01805
uniprot id: D1AX12
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

519441:SMON RS01840
gene id: 519441:SMON_RS01840
uniprot id: D1AX20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

519441:SMON RS04175
gene id: 519441:SMON_RS04175
uniprot id: D1AYB2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

519441:SMON RS00275
gene id: 519441:SMON_RS00275
uniprot id: D1AW78
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

519441:SMON RS06570
gene id: 519441:SMON_RS06570
uniprot id: D1AVI4
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

519441:SMON RS04975
gene id: 519441:SMON_RS04975
uniprot id: D1AYS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

519441:SMON RS02615
gene id: 519441:SMON_RS02615
uniprot id: D1AXG5
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

519441:SMON RS01570
gene id: 519441:SMON_RS01570
uniprot id: D1AWW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

519441:SMON RS04275
gene id: 519441:SMON_RS04275
uniprot id: D1AYD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

519441:SMON RS02420
gene id: 519441:SMON_RS02420
uniprot id: D1AXC9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

519441:SMON RS03680
gene id: 519441:SMON_RS03680
uniprot id: D1AY16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

519441:SMON RS03470
gene id: 519441:SMON_RS03470
uniprot id: D1AXX3
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS05475
gene id: 519441:SMON_RS05475
uniprot id: D1AUY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

519441:SMON RS03865
gene id: 519441:SMON_RS03865
uniprot id: D1AY51
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

519441:SMON RS02670
gene id: 519441:SMON_RS02670
uniprot id: D1AXH4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

519441:SMON RS05365
gene id: 519441:SMON_RS05365
uniprot id: D1AUW1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

519441:SMON RS02495
gene id: 519441:SMON_RS02495
uniprot id: D1AXE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

519441:SMON RS05425
gene id: 519441:SMON_RS05425
uniprot id: D1AUX1
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

519441:SMON RS01745
gene id: 519441:SMON_RS01745
uniprot id: D1AX00
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

519441:SMON RS08325
gene id: 519441:SMON_RS08325
uniprot id: D1AW96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

519441:SMON RS00795
gene id: 519441:SMON_RS00795
uniprot id: D1AWH4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

519441:SMON RS03805
gene id: 519441:SMON_RS03805
uniprot id: D1AY40
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

519441:SMON RS03930
gene id: 519441:SMON_RS03930
uniprot id: D1AY64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

519441:SMON RS03605
gene id: 519441:SMON_RS03605
uniprot id: D1AY01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

519441:SMON RS06620
gene id: 519441:SMON_RS06620
uniprot id: D1AVJ0
names: Subcellular Location Annotation
messages: Membrane

519441:SMON RS00895
gene id: 519441:SMON_RS00895
uniprot id: D1AWJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

519441:SMON RS00955
gene id: 519441:SMON_RS00955
uniprot id: D1AWK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

519441:SMON RS03875
gene id: 519441:SMON_RS03875
uniprot id: D1AY53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

519441:SMON RS01240
gene id: 519441:SMON_RS01240
uniprot id: D1AWQ5
names: Similarity
messages: Belongs to the bacterial secretin family.

519441:SMON RS05705
gene id: 519441:SMON_RS05705
uniprot id: D1AV24
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

519441:SMON RS02975
gene id: 519441:SMON_RS02975
uniprot id: D1AXM9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

519441:SMON RS00165
gene id: 519441:SMON_RS00165
uniprot id: D1AW57
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

519441:SMON RS07375
gene id: 519441:SMON_RS07375
uniprot id: D1AVX0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

519441:SMON RS00210
gene id: 519441:SMON_RS00210
uniprot id: D1AW65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

519441:SMON RS03755
gene id: 519441:SMON_RS03755
uniprot id: D1AY30
names: Similarity
messages: Belongs to the UDPGP type 2 family.

519441:SMON RS06230
gene id: 519441:SMON_RS06230
uniprot id: D1AVB5
names: Subcellular Location Annotation
messages: Membrane