516051:VC82 RS06730
gene id: 516051:VC82_RS06730
uniprot id: A0A0D5YSZ9
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS14820
gene id: 516051:VC82_RS14820
uniprot id: A0A0D5YXB8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

516051:VC82 RS02125
gene id: 516051:VC82_RS02125
uniprot id: A0A0D5YP73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

516051:VC82 RS10220
gene id: 516051:VC82_RS10220
uniprot id: A0A0D5YUX6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

516051:VC82 RS11220
gene id: 516051:VC82_RS11220
uniprot id: A0A0D5YU40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

516051:VC82 RS03000
gene id: 516051:VC82_RS03000
uniprot id: A0A0D5YPN6
names: Similarity
messages: Belongs to the ArsC family.

516051:VC82 RS09670
gene id: 516051:VC82_RS09670
uniprot id: A0A0D5YTI8
names: Similarity
messages: Belongs to the SCO1/2 family.

516051:VC82 RS07050
gene id: 516051:VC82_RS07050
uniprot id: A0A0D5YS13
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

516051:VC82 RS13630
gene id: 516051:VC82_RS13630
uniprot id: A0A0D5YWN2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

516051:VC82 RS12980
gene id: 516051:VC82_RS12980
uniprot id: A0A0D5YV31
names: Similarity
messages: Belongs to the isochorismate synthase family.

516051:VC82 RS00180
gene id: 516051:VC82_RS00180
uniprot id: A0A0D5YN31
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS10565
gene id: 516051:VC82_RS10565
uniprot id: A0A0D5YV43
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

516051:VC82 RS06360
gene id: 516051:VC82_RS06360
uniprot id: A0A0D5YRL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

516051:VC82 RS08900
gene id: 516051:VC82_RS08900
uniprot id: A0A0D5YU42
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

516051:VC82 RS05515
gene id: 516051:VC82_RS05515
uniprot id: A0A0D5YSC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS05825
gene id: 516051:VC82_RS05825
uniprot id: A0A0D5YRD3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS03705
gene id: 516051:VC82_RS03705
uniprot id: A0A0D5YRC5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

516051:VC82 RS01855
gene id: 516051:VC82_RS01855
uniprot id: A0A0D5YQE6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

516051:VC82 RS08690
gene id: 516051:VC82_RS08690
uniprot id: A0A0D5YU03
names: Similarity
messages: Belongs to the ParB family.

516051:VC82 RS10795
gene id: 516051:VC82_RS10795
uniprot id: A0A0D5YTV9
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

516051:VC82 RS13585
gene id: 516051:VC82_RS13585
uniprot id: A0A0D5YVN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

516051:VC82 RS11505
gene id: 516051:VC82_RS11505
uniprot id: A0A0D5YVI6
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS00170
gene id: 516051:VC82_RS00170
uniprot id: A0A0D5YPA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

516051:VC82 RS01230
gene id: 516051:VC82_RS01230
uniprot id: A0A0D5YQ08
names: Similarity
messages: Belongs to the ParB family.

516051:VC82 RS14435
gene id: 516051:VC82_RS14435
uniprot id: A0A0D5YX27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

516051:VC82 RS00220
gene id: 516051:VC82_RS00220
uniprot id: A0A0D5YPC0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS09640
gene id: 516051:VC82_RS09640
uniprot id: A0A0D5YUJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

516051:VC82 RS05275
gene id: 516051:VC82_RS05275
uniprot id: A0A0D5YR03
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS11985
gene id: 516051:VC82_RS11985
uniprot id: A0A0D5YUQ9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

516051:VC82 RS06810
gene id: 516051:VC82_RS06810
uniprot id: A0A0D5YSX4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

516051:VC82 RS03960
gene id: 516051:VC82_RS03960
uniprot id: A0A0D5YQB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

516051:VC82 RS06180
gene id: 516051:VC82_RS06180
uniprot id: A0A0D5YRH8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

516051:VC82 RS11775
gene id: 516051:VC82_RS11775
uniprot id: A0A0D5YUM4
names: Similarity
messages: Belongs to the UPF0047 family.

516051:VC82 RS14640
gene id: 516051:VC82_RS14640
uniprot id: A0A0D5YX67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

516051:VC82 RS03665
gene id: 516051:VC82_RS03665
uniprot id: A0A0D5YR91
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

516051:VC82 RS10210
gene id: 516051:VC82_RS10210
uniprot id: A0A0D5YUT5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

516051:VC82 RS06910
gene id: 516051:VC82_RS06910
uniprot id: A0A0D5YT46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

516051:VC82 RS00325
gene id: 516051:VC82_RS00325
uniprot id: A0A0D5YP90
names: Similarity
messages: Belongs to the CarB family.

516051:VC82 RS11140
gene id: 516051:VC82_RS11140
uniprot id: A0A0D5YVA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

516051:VC82 RS14630
gene id: 516051:VC82_RS14630
uniprot id: A0A0D5YX83
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

516051:VC82 RS14475
gene id: 516051:VC82_RS14475
uniprot id: A0A0D5YX53
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS09850
gene id: 516051:VC82_RS09850
uniprot id: A0A0D5YUM1
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

516051:VC82 RS06915
gene id: 516051:VC82_RS06915
uniprot id: A0A0D5YT21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

516051:VC82 RS14415
gene id: 516051:VC82_RS14415
uniprot id: A0A0D5YVV8
names: Similarity
messages: Belongs to the peptidase M1 family.

516051:VC82 RS10455
gene id: 516051:VC82_RS10455
uniprot id: A0A0D5YTQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

516051:VC82 RS07535
gene id: 516051:VC82_RS07535
uniprot id: A0A0D5YS86
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

516051:VC82 RS06185
gene id: 516051:VC82_RS06185
uniprot id: A0A0D5YSQ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS01980
gene id: 516051:VC82_RS01980
uniprot id: A0A0D5YQG4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

516051:VC82 RS08555
gene id: 516051:VC82_RS08555
uniprot id: A0A0D5YTY1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

516051:VC82 RS14815
gene id: 516051:VC82_RS14815
uniprot id: A0A0D5YWD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

516051:VC82 RS06065
gene id: 516051:VC82_RS06065
uniprot id: A0A0D5YSL9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

516051:VC82 RS06120
gene id: 516051:VC82_RS06120
uniprot id: A0A0D5YSI8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

516051:VC82 RS05895
gene id: 516051:VC82_RS05895
uniprot id: A0A0D5YSK0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

516051:VC82 RS12525
gene id: 516051:VC82_RS12525
uniprot id: A0A0D5YW10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

516051:VC82 RS11575
gene id: 516051:VC82_RS11575
uniprot id: A0A0D5YVP0
names: Similarity
messages: Belongs to the sterol desaturase family.

516051:VC82 RS10450
gene id: 516051:VC82_RS10450
uniprot id: A0A0D5YUX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

516051:VC82 RS05045
gene id: 516051:VC82_RS05045
uniprot id: A0A0D5YRX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

516051:VC82 RS05685
gene id: 516051:VC82_RS05685
uniprot id: A0A0D5YR81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS06170
gene id: 516051:VC82_RS06170
uniprot id: A0A0D5YSP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

516051:VC82 RS02070
gene id: 516051:VC82_RS02070
uniprot id: A0A0D5YQB1
names: Similarity
messages: Belongs to the AHA1 family.

516051:VC82 RS01995
gene id: 516051:VC82_RS01995
uniprot id: A0A0D5YQ96
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS07785
gene id: 516051:VC82_RS07785
uniprot id: A0A0D5YTK1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

516051:VC82 RS10730
gene id: 516051:VC82_RS10730
uniprot id: A0A0D5YU49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

516051:VC82 RS15040
gene id: 516051:VC82_RS15040
uniprot id: A0A0D5YXH5
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

516051:VC82 RS00105
gene id: 516051:VC82_RS00105
uniprot id: A0A0D5YPF6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

516051:VC82 RS10125
gene id: 516051:VC82_RS10125
uniprot id: A0A0D5YUR9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

516051:VC82 RS00300
gene id: 516051:VC82_RS00300
uniprot id: A0A0D5YP85
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

516051:VC82 RS00140
gene id: 516051:VC82_RS00140
uniprot id: A0A0D5YNE0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

516051:VC82 RS00045
gene id: 516051:VC82_RS00045
uniprot id: A0A0D5YP45
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

516051:VC82 RS01695
gene id: 516051:VC82_RS01695
uniprot id: A0A0D5YNZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

516051:VC82 RS09200
gene id: 516051:VC82_RS09200
uniprot id: A0A0D5YUC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

516051:VC82 RS09940
gene id: 516051:VC82_RS09940
uniprot id: A0A0D5YUS7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS12205
gene id: 516051:VC82_RS12205
uniprot id: A0A0D5YUY0
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

516051:VC82 RS05030
gene id: 516051:VC82_RS05030
uniprot id: A0A0D5YS24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

516051:VC82 RS04505
gene id: 516051:VC82_RS04505
uniprot id: A0A0D5YQM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

516051:VC82 RS05550
gene id: 516051:VC82_RS05550
uniprot id: A0A0D5YS70
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

516051:VC82 RS06495
gene id: 516051:VC82_RS06495
uniprot id: A0A0D5YSR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

516051:VC82 RS07760
gene id: 516051:VC82_RS07760
uniprot id: A0A0D5YTJ6
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS00655
gene id: 516051:VC82_RS00655
uniprot id: A0A0D5YNN0
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS03205
gene id: 516051:VC82_RS03205
uniprot id: A0A0D5YQZ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS08445
gene id: 516051:VC82_RS08445
uniprot id: A0A0D5YTW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

516051:VC82 RS03900
gene id: 516051:VC82_RS03900
uniprot id: A0A0D5YQ67
names: Similarity
messages: Belongs to the UPF0758 family.

516051:VC82 RS15020
gene id: 516051:VC82_RS15020
uniprot id: A0A0D5YWH8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

516051:VC82 RS01600
gene id: 516051:VC82_RS01600
uniprot id: A0A0D5YP39
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

516051:VC82 RS06440
gene id: 516051:VC82_RS06440
uniprot id: A0A0D5YSU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

516051:VC82 RS03815
gene id: 516051:VC82_RS03815
uniprot id: A0A0D5YRC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

516051:VC82 RS12215
gene id: 516051:VC82_RS12215
uniprot id: A0A0D5YUP6
names: Similarity
messages: Belongs to the threonine synthase family.

516051:VC82 RS03755
gene id: 516051:VC82_RS03755
uniprot id: A0A0D5YRD5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

516051:VC82 RS04920
gene id: 516051:VC82_RS04920
uniprot id: A0A0D5YQS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

516051:VC82 RS03830
gene id: 516051:VC82_RS03830
uniprot id: A0A0D5YRF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS11640
gene id: 516051:VC82_RS11640
uniprot id: A0A0D5YUK1
names: Similarity
messages: Belongs to the universal stress protein A family.

516051:VC82 RS04810
gene id: 516051:VC82_RS04810
uniprot id: A0A0D5YRW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS08435
gene id: 516051:VC82_RS08435
uniprot id: A0A0D5YTU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

516051:VC82 RS09780
gene id: 516051:VC82_RS09780
uniprot id: A0A0D5YTK9
names: Similarity
messages: Belongs to the fabD family.

516051:VC82 RS07700
gene id: 516051:VC82_RS07700
uniprot id: A0A0D5YTF1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

516051:VC82 RS06320
gene id: 516051:VC82_RS06320
uniprot id: A0A0D5YRK0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

516051:VC82 RS11530
gene id: 516051:VC82_RS11530
uniprot id: A0A0D5YVJ1
names: Similarity
messages: Belongs to the AHA1 family.

516051:VC82 RS12270
gene id: 516051:VC82_RS12270
uniprot id: A0A0D5YW23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

516051:VC82 RS09330
gene id: 516051:VC82_RS09330
uniprot id: A0A0D5YUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

516051:VC82 RS12175
gene id: 516051:VC82_RS12175
uniprot id: A0A0D5YVX7
names: Similarity
messages: Belongs to the peptidase C40 family.

516051:VC82 RS11800
gene id: 516051:VC82_RS11800
uniprot id: A0A0D5YUM8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS05385
gene id: 516051:VC82_RS05385
uniprot id: A0A0D5YS94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

516051:VC82 RS01595
gene id: 516051:VC82_RS01595
uniprot id: A0A0D5YQ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

516051:VC82 RS08590
gene id: 516051:VC82_RS08590
uniprot id: A0A0D5YU12
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

516051:VC82 RS03320
gene id: 516051:VC82_RS03320
uniprot id: A0A0D5YQY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

516051:VC82 RS09580
gene id: 516051:VC82_RS09580
uniprot id: A0A0D5YTA1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

516051:VC82 RS10060
gene id: 516051:VC82_RS10060
uniprot id: A0A0D5YUQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

516051:VC82 RS08000
gene id: 516051:VC82_RS08000
uniprot id: A0A0D5YTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

516051:VC82 RS10485
gene id: 516051:VC82_RS10485
uniprot id: A0A0D5YV29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

516051:VC82 RS06365
gene id: 516051:VC82_RS06365
uniprot id: A0A0D5YSS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

516051:VC82 RS02460
gene id: 516051:VC82_RS02460
uniprot id: A0A0D5YPM4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

516051:VC82 RS11705
gene id: 516051:VC82_RS11705
uniprot id: A0A0D5YUC9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

516051:VC82 RS07190
gene id: 516051:VC82_RS07190
uniprot id: A0A0D5YS21
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

516051:VC82 RS02090
gene id: 516051:VC82_RS02090
uniprot id: A0A0D5YQF1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

516051:VC82 RS05710
gene id: 516051:VC82_RS05710
uniprot id: A0A0D5YR87
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

516051:VC82 RS05680
gene id: 516051:VC82_RS05680
uniprot id: A0A0D5YS97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

516051:VC82 RS04115
gene id: 516051:VC82_RS04115
uniprot id: A0A0D5YRE4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

516051:VC82 RS12880
gene id: 516051:VC82_RS12880
uniprot id: A0A0D5YWC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

516051:VC82 RS08890
gene id: 516051:VC82_RS08890
uniprot id: A0A0D5YU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

516051:VC82 RS02690
gene id: 516051:VC82_RS02690
uniprot id: A0A0D5YPH2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

516051:VC82 RS06400
gene id: 516051:VC82_RS06400
uniprot id: A0A0D5YRL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

516051:VC82 RS05240
gene id: 516051:VC82_RS05240
uniprot id: A0A0D5YS49
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

516051:VC82 RS11415
gene id: 516051:VC82_RS11415
uniprot id: A0A0D5YU78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

516051:VC82 RS00890
gene id: 516051:VC82_RS00890
uniprot id: A0A0D5YNR9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

516051:VC82 RS13600
gene id: 516051:VC82_RS13600
uniprot id: A0A0D5YWR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

516051:VC82 RS02545
gene id: 516051:VC82_RS02545
uniprot id: A0A0D5YQI5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

516051:VC82 RS07830
gene id: 516051:VC82_RS07830
uniprot id: A0A0D5YSG6
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS12935
gene id: 516051:VC82_RS12935
uniprot id: A0A0D5YWD5
names: Similarity
messages: Belongs to the DapA family.

516051:VC82 RS07030
gene id: 516051:VC82_RS07030
uniprot id: A0A0D5YT68
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS12130
gene id: 516051:VC82_RS12130
uniprot id: A0A0D5YQN9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

516051:VC82 RS10535
gene id: 516051:VC82_RS10535
uniprot id: A0A0D5YTR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS07780
gene id: 516051:VC82_RS07780
uniprot id: A0A0D5YSF8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

516051:VC82 RS05940
gene id: 516051:VC82_RS05940
uniprot id: A0A0D5YRD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

516051:VC82 RS01765
gene id: 516051:VC82_RS01765
uniprot id: A0A0D5YQA3
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS04840
gene id: 516051:VC82_RS04840
uniprot id: A0A0D5YRU0
names: Similarity
messages: Belongs to the peptidase S41A family.

516051:VC82 RS06190
gene id: 516051:VC82_RS06190
uniprot id: A0A0D5YRJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

516051:VC82 RS10465
gene id: 516051:VC82_RS10465
uniprot id: A0A0D5YUX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS06655
gene id: 516051:VC82_RS06655
uniprot id: A0A0D5YSY6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

516051:VC82 RS12560
gene id: 516051:VC82_RS12560
uniprot id: A0A0D5YW39
names: Similarity
messages: Belongs to the RelE toxin family.

516051:VC82 RS02820
gene id: 516051:VC82_RS02820
uniprot id: A0A0D5YQX0
names: Similarity
messages: Belongs to the universal stress protein A family.

516051:VC82 RS14590
gene id: 516051:VC82_RS14590
uniprot id: A0A0D5YVY7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

516051:VC82 RS03780
gene id: 516051:VC82_RS03780
uniprot id: A0A0D5YRE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

516051:VC82 RS04590
gene id: 516051:VC82_RS04590
uniprot id: A0A0D5YRP5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

516051:VC82 RS11020
gene id: 516051:VC82_RS11020
uniprot id: A0A0D5YU06
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

516051:VC82 RS06275
gene id: 516051:VC82_RS06275
uniprot id: A0A0D5YSS3
names: Similarity
messages: Belongs to the RecJ family.

516051:VC82 RS12210
gene id: 516051:VC82_RS12210
uniprot id: A0A0D5YVW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS01300
gene id: 516051:VC82_RS01300
uniprot id: A0A0D5YPT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

516051:VC82 RS06535
gene id: 516051:VC82_RS06535
uniprot id: A0A0D5YRP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

516051:VC82 RS06660
gene id: 516051:VC82_RS06660
uniprot id: A0A0D5YSU3
names: Similarity
messages: Belongs to the transglycosylase Slt family.

516051:VC82 RS06445
gene id: 516051:VC82_RS06445
uniprot id: A0A0D5YSQ1
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS05595
gene id: 516051:VC82_RS05595
uniprot id: A0A0D5YSC5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

516051:VC82 RS00795
gene id: 516051:VC82_RS00795
uniprot id: A0A0D5YNF8
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS11480
gene id: 516051:VC82_RS11480
uniprot id: A0A0D5YVI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

516051:VC82 RS09490
gene id: 516051:VC82_RS09490
uniprot id: A0A0D5YTE7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

516051:VC82 RS14040
gene id: 516051:VC82_RS14040
uniprot id: A0A0D5YWW8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

516051:VC82 RS13935
gene id: 516051:VC82_RS13935
uniprot id: A0A0D5YWY1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

516051:VC82 RS05035
gene id: 516051:VC82_RS05035
uniprot id: A0A0D5YQY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

516051:VC82 RS03655
gene id: 516051:VC82_RS03655
uniprot id: A0A0D5YRB8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

516051:VC82 RS10930
gene id: 516051:VC82_RS10930
uniprot id: A0A0D5YVC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

516051:VC82 RS10805
gene id: 516051:VC82_RS10805
uniprot id: A0A0D5YV44
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

516051:VC82 RS06045
gene id: 516051:VC82_RS06045
uniprot id: A0A0D5YSH4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

516051:VC82 RS01180
gene id: 516051:VC82_RS01180
uniprot id: A0A0D5YPX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

516051:VC82 RS01165
gene id: 516051:VC82_RS01165
uniprot id: A0A0D5YNM7
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS11145
gene id: 516051:VC82_RS11145
uniprot id: A0A0D5YU30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

516051:VC82 RS14580
gene id: 516051:VC82_RS14580
uniprot id: A0A0D5YW56
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

516051:VC82 RS11755
gene id: 516051:VC82_RS11755
uniprot id: A0A0D5YVL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

516051:VC82 RS04580
gene id: 516051:VC82_RS04580
uniprot id: A0A0D5YQP4
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

516051:VC82 RS01915
gene id: 516051:VC82_RS01915
uniprot id: A0A0D5YQC6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

516051:VC82 RS06615
gene id: 516051:VC82_RS06615
uniprot id: A0A0D5YRP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

516051:VC82 RS11420
gene id: 516051:VC82_RS11420
uniprot id: A0A0D5YVL1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS05040
gene id: 516051:VC82_RS05040
uniprot id: A0A0D5YS05
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

516051:VC82 RS05705
gene id: 516051:VC82_RS05705
uniprot id: A0A0D5YSA3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

516051:VC82 RS12885
gene id: 516051:VC82_RS12885
uniprot id: A0A0D5YW91
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

516051:VC82 RS11175
gene id: 516051:VC82_RS11175
uniprot id: A0A0D5YVB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

516051:VC82 RS05315
gene id: 516051:VC82_RS05315
uniprot id: A0A0D5YS67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

516051:VC82 RS01715
gene id: 516051:VC82_RS01715
uniprot id: A0A0D5YQ53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

516051:VC82 RS00175
gene id: 516051:VC82_RS00175
uniprot id: A0A0D5YP63
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

516051:VC82 RS10330
gene id: 516051:VC82_RS10330
uniprot id: A0A0D5YUV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

516051:VC82 RS12420
gene id: 516051:VC82_RS12420
uniprot id: A0A0D5YVZ2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

516051:VC82 RS09155
gene id: 516051:VC82_RS09155
uniprot id: A0A0D5YU89
names: Similarity
messages: Belongs to the universal stress protein A family.

516051:VC82 RS11395
gene id: 516051:VC82_RS11395
uniprot id: A0A0D5YVK6
names: Similarity
messages: Belongs to the heat shock protein 90 family.

516051:VC82 RS12305
gene id: 516051:VC82_RS12305
uniprot id: A0A0D5YVZ8
names: Similarity
messages: Belongs to the RutC family.

516051:VC82 RS12905
gene id: 516051:VC82_RS12905
uniprot id: A0A0D5YWD0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

516051:VC82 RS05360
gene id: 516051:VC82_RS05360
uniprot id: A0A0D5YR46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

516051:VC82 RS00975
gene id: 516051:VC82_RS00975
uniprot id: A0A0D5YPM3
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS03785
gene id: 516051:VC82_RS03785
uniprot id: A0A0D5YQ82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

516051:VC82 RS04070
gene id: 516051:VC82_RS04070
uniprot id: A0A0D5YQC9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

516051:VC82 RS03600
gene id: 516051:VC82_RS03600
uniprot id: A0A0D5YQ10
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS01895
gene id: 516051:VC82_RS01895
uniprot id: A0A0D5YQ81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

516051:VC82 RS02610
gene id: 516051:VC82_RS02610
uniprot id: A0A0D5YQT1
names: Similarity
messages: Belongs to the glutamine synthetase family.

516051:VC82 RS05215
gene id: 516051:VC82_RS05215
uniprot id: A0A0D5YS44
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

516051:VC82 RS14635
gene id: 516051:VC82_RS14635
uniprot id: A0A0D5YW67
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

516051:VC82 RS04130
gene id: 516051:VC82_RS04130
uniprot id: A0A0D5YQD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS03345
gene id: 516051:VC82_RS03345
uniprot id: A0A0D5YQY7
names: Similarity
messages: Belongs to the asparagine synthetase family.

516051:VC82 RS12220
gene id: 516051:VC82_RS12220
uniprot id: A0A0D5YW15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

516051:VC82 RS05145
gene id: 516051:VC82_RS05145
uniprot id: A0A0D5YRZ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

516051:VC82 RS11750
gene id: 516051:VC82_RS11750
uniprot id: A0A0D5YUL8
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS07705
gene id: 516051:VC82_RS07705
uniprot id: A0A0D5YSE2
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

516051:VC82 RS04895
gene id: 516051:VC82_RS04895
uniprot id: A0A0D5YQS1
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS03455
gene id: 516051:VC82_RS03455
uniprot id: A0A0D5YR48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS05060
gene id: 516051:VC82_RS05060
uniprot id: A0A0D5YQY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

516051:VC82 RS03970
gene id: 516051:VC82_RS03970
uniprot id: A0A0D5YRB9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS14440
gene id: 516051:VC82_RS14440
uniprot id: A0A0D5YVW4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

516051:VC82 RS01935
gene id: 516051:VC82_RS01935
uniprot id: A0A0D5YPD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

516051:VC82 RS02915
gene id: 516051:VC82_RS02915
uniprot id: A0A0D5YPL9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

516051:VC82 RS13700
gene id: 516051:VC82_RS13700
uniprot id: A0A0D5YVH2
names: Similarity
messages: Belongs to the Dps family.

516051:VC82 RS07825
gene id: 516051:VC82_RS07825
uniprot id: A0A0D5YTH8
names: Similarity
messages: Belongs to the DtxR/MntR family.

516051:VC82 RS13195
gene id: 516051:VC82_RS13195
uniprot id: A0A0D5YWE4
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS09365
gene id: 516051:VC82_RS09365
uniprot id: A0A0D5YUD6
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS00285
gene id: 516051:VC82_RS00285
uniprot id: A0A0D5YPI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

516051:VC82 RS02625
gene id: 516051:VC82_RS02625
uniprot id: A0A0D5YQJ9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

516051:VC82 RS11055
gene id: 516051:VC82_RS11055
uniprot id: A0A0D5YV97
names: Similarity
messages: Belongs to the TrpC family.

516051:VC82 RS08465
gene id: 516051:VC82_RS08465
uniprot id: A0A0D5YST8
names: Similarity
messages: Belongs to the thioredoxin family.

516051:VC82 RS05985
gene id: 516051:VC82_RS05985
uniprot id: A0A0D5YSG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

516051:VC82 RS10160
gene id: 516051:VC82_RS10160
uniprot id: A0A0D5YUS6
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

516051:VC82 RS03165
gene id: 516051:VC82_RS03165
uniprot id: A0A0D5YR29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

516051:VC82 RS06175
gene id: 516051:VC82_RS06175
uniprot id: A0A0D5YSJ8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

516051:VC82 RS14200
gene id: 516051:VC82_RS14200
uniprot id: A0A0D5YVY9
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS02335
gene id: 516051:VC82_RS02335
uniprot id: A0A0D5YQI8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

516051:VC82 RS13720
gene id: 516051:VC82_RS13720
uniprot id: A0A0D5YWM5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

516051:VC82 RS01550
gene id: 516051:VC82_RS01550
uniprot id: A0A0D5YQ49
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

516051:VC82 RS08450
gene id: 516051:VC82_RS08450
uniprot id: A0A0D5YSN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

516051:VC82 RS12225
gene id: 516051:VC82_RS12225
uniprot id: A0A0D5YVY6
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

516051:VC82 RS06025
gene id: 516051:VC82_RS06025
uniprot id: A0A0D5YSM7
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

516051:VC82 RS03175
gene id: 516051:VC82_RS03175
uniprot id: A0A0D5YQZ2
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS02565
gene id: 516051:VC82_RS02565
uniprot id: A0A0D5YQM6
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

516051:VC82 RS14245
gene id: 516051:VC82_RS14245
uniprot id: A0A0D5YX08
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

516051:VC82 RS11475
gene id: 516051:VC82_RS11475
uniprot id: A0A0D5YU88
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

516051:VC82 RS07715
gene id: 516051:VC82_RS07715
uniprot id: A0A0D5YSB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

516051:VC82 RS06240
gene id: 516051:VC82_RS06240
uniprot id: A0A0D5YRI6
names: Similarity
messages: Belongs to the universal stress protein A family.

516051:VC82 RS05080
gene id: 516051:VC82_RS05080
uniprot id: A0A0D5YS33
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

516051:VC82 RS12280
gene id: 516051:VC82_RS12280
uniprot id: A0A0D5YUZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

516051:VC82 RS00160
gene id: 516051:VC82_RS00160
uniprot id: A0A0D5YPG5
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS07145
gene id: 516051:VC82_RS07145
uniprot id: A0A0D5YT53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

516051:VC82 RS14235
gene id: 516051:VC82_RS14235
uniprot id: A0A0D5YVS8
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS07180
gene id: 516051:VC82_RS07180
uniprot id: A0A0D5YS36
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

516051:VC82 RS04315
gene id: 516051:VC82_RS04315
uniprot id: A0A0D5YRN0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

516051:VC82 RS13635
gene id: 516051:VC82_RS13635
uniprot id: A0A0D5YVP6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

516051:VC82 RS00905
gene id: 516051:VC82_RS00905
uniprot id: A0A0D5YNI0
names: Similarity
messages: Belongs to the peptidase S13 family.

516051:VC82 RS06355
gene id: 516051:VC82_RS06355
uniprot id: A0A0D5YSU0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

516051:VC82 RS06325
gene id: 516051:VC82_RS06325
uniprot id: A0A0D5YST3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

516051:VC82 RS09615
gene id: 516051:VC82_RS09615
uniprot id: A0A0D5YUI8
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

516051:VC82 RS10990
gene id: 516051:VC82_RS10990
uniprot id: A0A0D5YU98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

516051:VC82 RS05330
gene id: 516051:VC82_RS05330
uniprot id: A0A0D5YS84
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

516051:VC82 RS04435
gene id: 516051:VC82_RS04435
uniprot id: A0A0D5YRS4
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

516051:VC82 RS07740
gene id: 516051:VC82_RS07740
uniprot id: A0A0D5YSC1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS05835
gene id: 516051:VC82_RS05835
uniprot id: A0A0D5YSC7
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS00690
gene id: 516051:VC82_RS00690
uniprot id: A0A0D5YPG6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

516051:VC82 RS06760
gene id: 516051:VC82_RS06760
uniprot id: A0A0D5YT03
names: Similarity
messages: Belongs to the GARS family.

516051:VC82 RS13005
gene id: 516051:VC82_RS13005
uniprot id: A0A0D5YV35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

516051:VC82 RS04400
gene id: 516051:VC82_RS04400
uniprot id: A0A0D5YQH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

516051:VC82 RS07335
gene id: 516051:VC82_RS07335
uniprot id: A0A0D5YTC0
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

516051:VC82 RS03585
gene id: 516051:VC82_RS03585
uniprot id: A0A0D5YQ50
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS06965
gene id: 516051:VC82_RS06965
uniprot id: A0A0D5YT54
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

516051:VC82 RS10000
gene id: 516051:VC82_RS10000
uniprot id: A0A0D5YTQ2
names: Similarity
messages: Belongs to the Skp family.

516051:VC82 RS01925
gene id: 516051:VC82_RS01925
uniprot id: A0A0D5YP37
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

516051:VC82 RS09405
gene id: 516051:VC82_RS09405
uniprot id: A0A0D5YUG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

516051:VC82 RS09525
gene id: 516051:VC82_RS09525
uniprot id: A0A0D5YUH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

516051:VC82 RS13230
gene id: 516051:VC82_RS13230
uniprot id: A0A0D5YWC7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS09920
gene id: 516051:VC82_RS09920
uniprot id: A0A0D5YUN0
names: Similarity
messages: Belongs to the DinB family.

516051:VC82 RS05250
gene id: 516051:VC82_RS05250
uniprot id: A0A0D5YQZ8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

516051:VC82 RS01755
gene id: 516051:VC82_RS01755
uniprot id: A0A0D5YQC8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

516051:VC82 RS02280
gene id: 516051:VC82_RS02280
uniprot id: A0A0D5YQH8
names: Subcellular Location Annotation
messages: Nucleus

516051:VC82 RS13155
gene id: 516051:VC82_RS13155
uniprot id: A0A0D5YWB3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

516051:VC82 RS05470
gene id: 516051:VC82_RS05470
uniprot id: A0A0D5YR64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

516051:VC82 RS08005
gene id: 516051:VC82_RS08005
uniprot id: A0A0D5YSK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

516051:VC82 RS06750
gene id: 516051:VC82_RS06750
uniprot id: A0A0D5YRT2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

516051:VC82 RS00385
gene id: 516051:VC82_RS00385
uniprot id: A0A0D5YNI5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

516051:VC82 RS03340
gene id: 516051:VC82_RS03340
uniprot id: A0A0D5YR23
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

516051:VC82 RS00165
gene id: 516051:VC82_RS00165
uniprot id: A0A0D5YNE4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

516051:VC82 RS14470
gene id: 516051:VC82_RS14470
uniprot id: A0A0D5YX90
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

516051:VC82 RS00920
gene id: 516051:VC82_RS00920
uniprot id: A0A0D5YPS3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

516051:VC82 RS14205
gene id: 516051:VC82_RS14205
uniprot id: A0A0D5YWX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

516051:VC82 RS00480
gene id: 516051:VC82_RS00480
uniprot id: A0A0D5YPM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

516051:VC82 RS03645
gene id: 516051:VC82_RS03645
uniprot id: A0A0D5YR52
names: Similarity
messages: Belongs to the citrate synthase family.

516051:VC82 RS10520
gene id: 516051:VC82_RS10520
uniprot id: A0A0D5YUY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

516051:VC82 RS09480
gene id: 516051:VC82_RS09480
uniprot id: A0A0D5YUK0
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

516051:VC82 RS12950
gene id: 516051:VC82_RS12950
uniprot id: A0A0D5YW77
names: Similarity
messages: Belongs to the proline racemase family.

516051:VC82 RS11650
gene id: 516051:VC82_RS11650
uniprot id: A0A0D5YUC1
names: Similarity
messages: Belongs to the universal stress protein A family.

516051:VC82 RS10505
gene id: 516051:VC82_RS10505
uniprot id: A0A0D5YUY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

516051:VC82 RS00150
gene id: 516051:VC82_RS00150
uniprot id: A0A0D5YP60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

516051:VC82 RS06950
gene id: 516051:VC82_RS06950
uniprot id: A0A0D5YRZ0
names: Similarity
messages: Belongs to the sulfatase family.

516051:VC82 RS11645
gene id: 516051:VC82_RS11645
uniprot id: A0A0D5YVK0
names: Similarity
messages: Belongs to the universal stress protein A family.

516051:VC82 RS06680
gene id: 516051:VC82_RS06680
uniprot id: A0A0D5YSZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

516051:VC82 RS11520
gene id: 516051:VC82_RS11520
uniprot id: A0A0D5YUA0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS13660
gene id: 516051:VC82_RS13660
uniprot id: A0A0D5YVQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

516051:VC82 RS10155
gene id: 516051:VC82_RS10155
uniprot id: A0A0D5YTT4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

516051:VC82 RS02150
gene id: 516051:VC82_RS02150
uniprot id: A0A0D5YP77
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS06330
gene id: 516051:VC82_RS06330
uniprot id: A0A0D5YRL4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS02185
gene id: 516051:VC82_RS02185
uniprot id: A0A0D5YPH7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

516051:VC82 RS00310
gene id: 516051:VC82_RS00310
uniprot id: A0A0D5YPI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

516051:VC82 RS05500
gene id: 516051:VC82_RS05500
uniprot id: A0A0D5YSA1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

516051:VC82 RS11215
gene id: 516051:VC82_RS11215
uniprot id: A0A0D5YVB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

516051:VC82 RS05120
gene id: 516051:VC82_RS05120
uniprot id: A0A0D5YRY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

516051:VC82 RS11860
gene id: 516051:VC82_RS11860
uniprot id: A0A0D5YVN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS12340
gene id: 516051:VC82_RS12340
uniprot id: A0A0D5YVY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

516051:VC82 RS01640
gene id: 516051:VC82_RS01640
uniprot id: A0A0D5YQ31
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

516051:VC82 RS00755
gene id: 516051:VC82_RS00755
uniprot id: A0A0D5YQN9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

516051:VC82 RS06450
gene id: 516051:VC82_RS06450
uniprot id: A0A0D5YRL8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

516051:VC82 RS04155
gene id: 516051:VC82_RS04155
uniprot id: A0A0D5YQE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

516051:VC82 RS09420
gene id: 516051:VC82_RS09420
uniprot id: A0A0D5YUE5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

516051:VC82 RS12190
gene id: 516051:VC82_RS12190
uniprot id: A0A0D5YUP1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

516051:VC82 RS04870
gene id: 516051:VC82_RS04870
uniprot id: A0A0D5YQR6
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS02165
gene id: 516051:VC82_RS02165
uniprot id: A0A0D5YQG2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

516051:VC82 RS07255
gene id: 516051:VC82_RS07255
uniprot id: A0A0D5YS52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

516051:VC82 RS02900
gene id: 516051:VC82_RS02900
uniprot id: A0A0D5YPV1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

516051:VC82 RS11790
gene id: 516051:VC82_RS11790
uniprot id: A0A0D5YVS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

516051:VC82 RS11195
gene id: 516051:VC82_RS11195
uniprot id: A0A0D5YU35
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

516051:VC82 RS12260
gene id: 516051:VC82_RS12260
uniprot id: A0A0D5YVW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

516051:VC82 RS00185
gene id: 516051:VC82_RS00185
uniprot id: A0A0D5YPH0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

516051:VC82 RS13840
gene id: 516051:VC82_RS13840
uniprot id: A0A0D5YWS5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS04395
gene id: 516051:VC82_RS04395
uniprot id: A0A0D5YRL6
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS07370
gene id: 516051:VC82_RS07370
uniprot id: A0A0D5YTC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

516051:VC82 RS03530
gene id: 516051:VC82_RS03530
uniprot id: A0A0D5YR94
names: Similarity
messages: Belongs to the RutC family.

516051:VC82 RS02260
gene id: 516051:VC82_RS02260
uniprot id: A0A0D5YP96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

516051:VC82 RS12635
gene id: 516051:VC82_RS12635
uniprot id: A0A0D5YW25
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS14960
gene id: 516051:VC82_RS14960
uniprot id: A0A0D5YXJ5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

516051:VC82 RS09205
gene id: 516051:VC82_RS09205
uniprot id: A0A0D5YT60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

516051:VC82 RS11435
gene id: 516051:VC82_RS11435
uniprot id: A0A0D5YVG0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

516051:VC82 RS08330
gene id: 516051:VC82_RS08330
uniprot id: A0A0D5YTS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

516051:VC82 RS08260
gene id: 516051:VC82_RS08260
uniprot id: A0A0D5YSP9
names: Similarity
messages: Belongs to the aspartokinase family.

516051:VC82 RS07340
gene id: 516051:VC82_RS07340
uniprot id: A0A0D5YS50
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

516051:VC82 RS09875
gene id: 516051:VC82_RS09875
uniprot id: A0A0D5YUR8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

516051:VC82 RS05650
gene id: 516051:VC82_RS05650
uniprot id: A0A0D5YS93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS06125
gene id: 516051:VC82_RS06125
uniprot id: A0A0D5YRH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

516051:VC82 RS09340
gene id: 516051:VC82_RS09340
uniprot id: A0A0D5YUD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

516051:VC82 RS13130
gene id: 516051:VC82_RS13130
uniprot id: A0A0D5YV61
names: Similarity
messages: Belongs to the threonine aldolase family.

516051:VC82 RS09620
gene id: 516051:VC82_RS09620
uniprot id: A0A0D5YTH7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

516051:VC82 RS14985
gene id: 516051:VC82_RS14985
uniprot id: A0A0D5YXJ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

516051:VC82 RS14990
gene id: 516051:VC82_RS14990
uniprot id: A0A0D5YXG6
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

516051:VC82 RS07300
gene id: 516051:VC82_RS07300
uniprot id: A0A0D5YT80
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

516051:VC82 RS00065
gene id: 516051:VC82_RS00065
uniprot id: A0A0D5YP87
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

516051:VC82 RS13455
gene id: 516051:VC82_RS13455
uniprot id: A0A0D5YVL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS02375
gene id: 516051:VC82_RS02375
uniprot id: A0A0D5YPB5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

516051:VC82 RS03560
gene id: 516051:VC82_RS03560
uniprot id: A0A0D5YQ46
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

516051:VC82 RS01735
gene id: 516051:VC82_RS01735
uniprot id: A0A0D5YQ99
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS09160
gene id: 516051:VC82_RS09160
uniprot id: A0A0D5YT51
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

516051:VC82 RS11875
gene id: 516051:VC82_RS11875
uniprot id: A0A0D5YVQ3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS07395
gene id: 516051:VC82_RS07395
uniprot id: A0A0D5YTC7
names: Similarity
messages: Belongs to the peptidase S58 family.

516051:VC82 RS06605
gene id: 516051:VC82_RS06605
uniprot id: A0A0D5YSX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

516051:VC82 RS07880
gene id: 516051:VC82_RS07880
uniprot id: A0A0D5YTL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

516051:VC82 RS03300
gene id: 516051:VC82_RS03300
uniprot id: A0A0D5YPU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

516051:VC82 RS01680
gene id: 516051:VC82_RS01680
uniprot id: A0A0D5YP83
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

516051:VC82 RS03170
gene id: 516051:VC82_RS03170
uniprot id: A0A0D5YPZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

516051:VC82 RS15115
gene id: 516051:VC82_RS15115
uniprot id: A0A0D5YXI7
names: Similarity
messages: Belongs to the LOG family.

516051:VC82 RS09335
gene id: 516051:VC82_RS09335
uniprot id: A0A0D5YT85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

516051:VC82 RS05380
gene id: 516051:VC82_RS05380
uniprot id: A0A0D5YR21
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS07160
gene id: 516051:VC82_RS07160
uniprot id: A0A0D5YT89
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

516051:VC82 RS05245
gene id: 516051:VC82_RS05245
uniprot id: A0A0D5YS11
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

516051:VC82 RS09910
gene id: 516051:VC82_RS09910
uniprot id: A0A0D5YTF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

516051:VC82 RS07100
gene id: 516051:VC82_RS07100
uniprot id: A0A0D5YT45
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

516051:VC82 RS11205
gene id: 516051:VC82_RS11205
uniprot id: A0A0D5YVC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

516051:VC82 RS12480
gene id: 516051:VC82_RS12480
uniprot id: A0A0D5YUU3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

516051:VC82 RS00395
gene id: 516051:VC82_RS00395
uniprot id: A0A0D5YPA4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS09905
gene id: 516051:VC82_RS09905
uniprot id: A0A0D5YUM9
names: Similarity
messages: Belongs to the peptidase S49 family.

516051:VC82 RS09415
gene id: 516051:VC82_RS09415
uniprot id: A0A0D5YTA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

516051:VC82 RS04855
gene id: 516051:VC82_RS04855
uniprot id: A0A0D5YQU8
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

516051:VC82 RS02435
gene id: 516051:VC82_RS02435
uniprot id: A0A0D5YPM1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

516051:VC82 RS12985
gene id: 516051:VC82_RS12985
uniprot id: A0A0D5YWE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

516051:VC82 RS04805
gene id: 516051:VC82_RS04805
uniprot id: A0A0D5YQT7
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

516051:VC82 RS04550
gene id: 516051:VC82_RS04550
uniprot id: A0A0D5YQN9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

516051:VC82 RS05920
gene id: 516051:VC82_RS05920
uniprot id: A0A0D5YSK5
names: Similarity
messages: Belongs to the ArsC family.

516051:VC82 RS15810
gene id: 516051:VC82_RS15810
uniprot id: A0A0D5YTY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

516051:VC82 RS13645
gene id: 516051:VC82_RS13645
uniprot id: A0A0D5YVG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS03575
gene id: 516051:VC82_RS03575
uniprot id: A0A0D5YQ04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

516051:VC82 RS05340
gene id: 516051:VC82_RS05340
uniprot id: A0A0D5YS71
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS11290
gene id: 516051:VC82_RS11290
uniprot id: A0A0D5YUF1
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

516051:VC82 RS07645
gene id: 516051:VC82_RS07645
uniprot id: A0A0D5YTH5
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS08845
gene id: 516051:VC82_RS08845
uniprot id: A0A0D5YU33
names: Similarity
messages: Belongs to the AHA1 family.

516051:VC82 RS02250
gene id: 516051:VC82_RS02250
uniprot id: A0A0D5YQH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

516051:VC82 RS09325
gene id: 516051:VC82_RS09325
uniprot id: A0A0D5YUF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

516051:VC82 RS01240
gene id: 516051:VC82_RS01240
uniprot id: A0A0D5YPY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

516051:VC82 RS07205
gene id: 516051:VC82_RS07205
uniprot id: A0A0D5YS41
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

516051:VC82 RS00560
gene id: 516051:VC82_RS00560
uniprot id: A0A0D5YNL3
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

516051:VC82 RS08925
gene id: 516051:VC82_RS08925
uniprot id: A0A0D5YU41
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

516051:VC82 RS10825
gene id: 516051:VC82_RS10825
uniprot id: A0A0D5YV96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

516051:VC82 RS07890
gene id: 516051:VC82_RS07890
uniprot id: A0A0D5YTM7
names: Similarity
messages: Belongs to the SCO1/2 family.

516051:VC82 RS01720
gene id: 516051:VC82_RS01720
uniprot id: A0A0D5YP01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

516051:VC82 RS03930
gene id: 516051:VC82_RS03930
uniprot id: A0A0D5YRH2
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS08585
gene id: 516051:VC82_RS08585
uniprot id: A0A0D5YSQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

516051:VC82 RS07200
gene id: 516051:VC82_RS07200
uniprot id: A0A0D5YT62
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

516051:VC82 RS00090
gene id: 516051:VC82_RS00090
uniprot id: A0A0D5YP92
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

516051:VC82 RS03265
gene id: 516051:VC82_RS03265
uniprot id: A0A0D5YR07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

516051:VC82 RS08040
gene id: 516051:VC82_RS08040
uniprot id: A0A0D5YSK7
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

516051:VC82 RS06435
gene id: 516051:VC82_RS06435
uniprot id: A0A0D5YRM7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

516051:VC82 RS00200
gene id: 516051:VC82_RS00200
uniprot id: A0A0D5YP67
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

516051:VC82 RS14615
gene id: 516051:VC82_RS14615
uniprot id: A0A0D5YX62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

516051:VC82 RS13610
gene id: 516051:VC82_RS13610
uniprot id: A0A0D5YVP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

516051:VC82 RS14870
gene id: 516051:VC82_RS14870
uniprot id: A0A0D5YWE7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

516051:VC82 RS00265
gene id: 516051:VC82_RS00265
uniprot id: A0A0D5YNG5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS05400
gene id: 516051:VC82_RS05400
uniprot id: A0A0D5YS42
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

516051:VC82 RS07800
gene id: 516051:VC82_RS07800
uniprot id: A0A0D5YTH3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS03185
gene id: 516051:VC82_RS03185
uniprot id: A0A0D5YPS2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

516051:VC82 RS07265
gene id: 516051:VC82_RS07265
uniprot id: A0A0D5YS35
names: Similarity
messages: Belongs to the peptidase S8 family.

516051:VC82 RS02620
gene id: 516051:VC82_RS02620
uniprot id: A0A0D5YQN7
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS12550
gene id: 516051:VC82_RS12550
uniprot id: A0A0D5YUV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

516051:VC82 RS06160
gene id: 516051:VC82_RS06160
uniprot id: A0A0D5YSQ3
names: Similarity
messages: Belongs to the pyruvate kinase family.

516051:VC82 RS03595
gene id: 516051:VC82_RS03595
uniprot id: A0A0D5YR42
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS14385
gene id: 516051:VC82_RS14385
uniprot id: A0A0D5YX17
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

516051:VC82 RS01645
gene id: 516051:VC82_RS01645
uniprot id: A0A0D5YNY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

516051:VC82 RS05295
gene id: 516051:VC82_RS05295
uniprot id: A0A0D5YS20
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS04495
gene id: 516051:VC82_RS04495
uniprot id: A0A0D5YQJ2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

516051:VC82 RS03765
gene id: 516051:VC82_RS03765
uniprot id: A0A0D5YRB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

516051:VC82 RS10370
gene id: 516051:VC82_RS10370
uniprot id: A0A0D5YTY0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS10945
gene id: 516051:VC82_RS10945
uniprot id: A0A0D5YV67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

516051:VC82 RS00070
gene id: 516051:VC82_RS00070
uniprot id: A0A0D5YP47
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

516051:VC82 RS09570
gene id: 516051:VC82_RS09570
uniprot id: A0A0D5YTG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

516051:VC82 RS04510
gene id: 516051:VC82_RS04510
uniprot id: A0A0D5YRR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

516051:VC82 RS04880
gene id: 516051:VC82_RS04880
uniprot id: A0A0D5YQV2
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

516051:VC82 RS07765
gene id: 516051:VC82_RS07765
uniprot id: A0A0D5YSC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS07635
gene id: 516051:VC82_RS07635
uniprot id: A0A0D5YTH2
names: Similarity
messages: Belongs to the DinB family.

516051:VC82 RS11660
gene id: 516051:VC82_RS11660
uniprot id: A0A0D5YVL7
names: Similarity
messages: Belongs to the universal stress protein A family.

516051:VC82 RS10585
gene id: 516051:VC82_RS10585
uniprot id: A0A0D5YTS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

516051:VC82 RS08385
gene id: 516051:VC82_RS08385
uniprot id: A0A0D5YSS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

516051:VC82 RS07685
gene id: 516051:VC82_RS07685
uniprot id: A0A0D5YTI0
names: Similarity
messages: Belongs to the YicC/YloC family.

516051:VC82 RS05545
gene id: 516051:VC82_RS05545
uniprot id: A0A0D5YSB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

516051:VC82 RS14885
gene id: 516051:VC82_RS14885
uniprot id: A0A0D5YXI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS10560
gene id: 516051:VC82_RS10560
uniprot id: A0A0D5YTS0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

516051:VC82 RS05900
gene id: 516051:VC82_RS05900
uniprot id: A0A0D5YRE6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

516051:VC82 RS03695
gene id: 516051:VC82_RS03695
uniprot id: A0A0D5YR63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

516051:VC82 RS02790
gene id: 516051:VC82_RS02790
uniprot id: A0A0D5YPJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

516051:VC82 RS03690
gene id: 516051:VC82_RS03690
uniprot id: A0A0D5YR97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

516051:VC82 RS05965
gene id: 516051:VC82_RS05965
uniprot id: A0A0D5YRE2
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS07325
gene id: 516051:VC82_RS07325
uniprot id: A0A0D5YT84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

516051:VC82 RS10145
gene id: 516051:VC82_RS10145
uniprot id: A0A0D5YUW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

516051:VC82 RS03100
gene id: 516051:VC82_RS03100
uniprot id: A0A0D5YQU1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

516051:VC82 RS13395
gene id: 516051:VC82_RS13395
uniprot id: A0A0D5YWI5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

516051:VC82 RS14530
gene id: 516051:VC82_RS14530
uniprot id: A0A0D5YW46
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

516051:VC82 RS02835
gene id: 516051:VC82_RS02835
uniprot id: A0A0D5YQP1
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

516051:VC82 RS13110
gene id: 516051:VC82_RS13110
uniprot id: A0A0D5YWG8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS09445
gene id: 516051:VC82_RS09445
uniprot id: A0A0D5YUE9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

516051:VC82 RS14445
gene id: 516051:VC82_RS14445
uniprot id: A0A0D5YX87
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS04730
gene id: 516051:VC82_RS04730
uniprot id: A0A0D5YQS4
names: Similarity
messages: Belongs to the arginase family.

516051:VC82 RS14710
gene id: 516051:VC82_RS14710
uniprot id: A0A0D5YXB4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS05760
gene id: 516051:VC82_RS05760
uniprot id: A0A0D5YRA0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS01205
gene id: 516051:VC82_RS01205
uniprot id: A0A0D5YQ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

516051:VC82 RS07210
gene id: 516051:VC82_RS07210
uniprot id: A0A0D5YT97
names: Similarity
messages: Belongs to the SufE family.

516051:VC82 RS00450
gene id: 516051:VC82_RS00450
uniprot id: A0A0D5YN85
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

516051:VC82 RS09990
gene id: 516051:VC82_RS09990
uniprot id: A0A0D5YUT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

516051:VC82 RS03715
gene id: 516051:VC82_RS03715
uniprot id: A0A0D5YRA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

516051:VC82 RS02160
gene id: 516051:VC82_RS02160
uniprot id: A0A0D5YPH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

516051:VC82 RS07895
gene id: 516051:VC82_RS07895
uniprot id: A0A0D5YTJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

516051:VC82 RS08625
gene id: 516051:VC82_RS08625
uniprot id: A0A0D5YTY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

516051:VC82 RS08575
gene id: 516051:VC82_RS08575
uniprot id: A0A0D5YSV9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS11005
gene id: 516051:VC82_RS11005
uniprot id: A0A0D5YVD5
names: Similarity
messages: Belongs to the UPF0246 family.

516051:VC82 RS07290
gene id: 516051:VC82_RS07290
uniprot id: A0A0D5YS40
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS01375
gene id: 516051:VC82_RS01375
uniprot id: A0A0D5YPV2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

516051:VC82 RS13500
gene id: 516051:VC82_RS13500
uniprot id: A0A0D5YWP6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

516051:VC82 RS04595
gene id: 516051:VC82_RS04595
uniprot id: A0A0D5YQL1
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS02490
gene id: 516051:VC82_RS02490
uniprot id: A0A0D5YQL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

516051:VC82 RS09655
gene id: 516051:VC82_RS09655
uniprot id: A0A0D5YTB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

516051:VC82 RS14125
gene id: 516051:VC82_RS14125
uniprot id: A0A0D5YVX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

516051:VC82 RS07930
gene id: 516051:VC82_RS07930
uniprot id: A0A0D5YSI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

516051:VC82 RS09290
gene id: 516051:VC82_RS09290
uniprot id: A0A0D5YT24
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

516051:VC82 RS14900
gene id: 516051:VC82_RS14900
uniprot id: A0A0D5YXC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

516051:VC82 RS14605
gene id: 516051:VC82_RS14605
uniprot id: A0A0D5YW60
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

516051:VC82 RS01685
gene id: 516051:VC82_RS01685
uniprot id: A0A0D5YQ91
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

516051:VC82 RS11000
gene id: 516051:VC82_RS11000
uniprot id: A0A0D5YU01
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

516051:VC82 RS09460
gene id: 516051:VC82_RS09460
uniprot id: A0A0D5YUG8
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

516051:VC82 RS14260
gene id: 516051:VC82_RS14260
uniprot id: A0A0D5YVT4
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

516051:VC82 RS05260
gene id: 516051:VC82_RS05260
uniprot id: A0A0D5YR24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

516051:VC82 RS00365
gene id: 516051:VC82_RS00365
uniprot id: A0A0D5YPF3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

516051:VC82 RS09685
gene id: 516051:VC82_RS09685
uniprot id: A0A0D5YUN6
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS13410
gene id: 516051:VC82_RS13410
uniprot id: A0A0D5YVB6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

516051:VC82 RS13380
gene id: 516051:VC82_RS13380
uniprot id: A0A0D5YWF8
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS10305
gene id: 516051:VC82_RS10305
uniprot id: A0A0D5YUU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

516051:VC82 RS09645
gene id: 516051:VC82_RS09645
uniprot id: A0A0D5YTI3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

516051:VC82 RS12290
gene id: 516051:VC82_RS12290
uniprot id: A0A0D5YUR2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS05690
gene id: 516051:VC82_RS05690
uniprot id: A0A0D5YSF6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

516051:VC82 RS03680
gene id: 516051:VC82_RS03680
uniprot id: A0A0D5YRC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

516051:VC82 RS07015
gene id: 516051:VC82_RS07015
uniprot id: A0A0D5YT63
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

516051:VC82 RS04770
gene id: 516051:VC82_RS04770
uniprot id: A0A0D5YQP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

516051:VC82 RS03570
gene id: 516051:VC82_RS03570
uniprot id: A0A0D5YR37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

516051:VC82 RS12455
gene id: 516051:VC82_RS12455
uniprot id: A0A0D5YUU0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

516051:VC82 RS14460
gene id: 516051:VC82_RS14460
uniprot id: A0A0D5YX31
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS13930
gene id: 516051:VC82_RS13930
uniprot id: A0A0D5YVL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

516051:VC82 RS13825
gene id: 516051:VC82_RS13825
uniprot id: A0A0D5YWP5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

516051:VC82 RS00130
gene id: 516051:VC82_RS00130
uniprot id: A0A0D5YN18
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

516051:VC82 RS10625
gene id: 516051:VC82_RS10625
uniprot id: A0A0D5YV06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

516051:VC82 RS05630
gene id: 516051:VC82_RS05630
uniprot id: A0A0D5YR70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

516051:VC82 RS01725
gene id: 516051:VC82_RS01725
uniprot id: A0A0D5YQC2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

516051:VC82 RS10425
gene id: 516051:VC82_RS10425
uniprot id: A0A0D5YUW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

516051:VC82 RS03710
gene id: 516051:VC82_RS03710
uniprot id: A0A0D5YQ72
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

516051:VC82 RS06505
gene id: 516051:VC82_RS06505
uniprot id: A0A0D5YSW6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

516051:VC82 RS10275
gene id: 516051:VC82_RS10275
uniprot id: A0A0D5YTV4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

516051:VC82 RS01330
gene id: 516051:VC82_RS01330
uniprot id: A0A0D5YNP9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

516051:VC82 RS05555
gene id: 516051:VC82_RS05555
uniprot id: A0A0D5YR55
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

516051:VC82 RS14130
gene id: 516051:VC82_RS14130
uniprot id: A0A0D5YWW1
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

516051:VC82 RS13350
gene id: 516051:VC82_RS13350
uniprot id: A0A0D5YVJ0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

516051:VC82 RS04665
gene id: 516051:VC82_RS04665
uniprot id: A0A0D5YRQ5
names: Similarity
messages: Belongs to the SusD family.

516051:VC82 RS07615
gene id: 516051:VC82_RS07615
uniprot id: A0A0D5YSA0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

516051:VC82 RS14915
gene id: 516051:VC82_RS14915
uniprot id: A0A0D5YXF5
names: Similarity
messages: Belongs to the DSD1 family.

516051:VC82 RS14250
gene id: 516051:VC82_RS14250
uniprot id: A0A0D5YVZ7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

516051:VC82 RS08360
gene id: 516051:VC82_RS08360
uniprot id: A0A0D5YSR9
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS14565
gene id: 516051:VC82_RS14565
uniprot id: A0A0D5YVY3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

516051:VC82 RS10985
gene id: 516051:VC82_RS10985
uniprot id: A0A0D5YV81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

516051:VC82 RS04185
gene id: 516051:VC82_RS04185
uniprot id: A0A0D5YRI8
names: Similarity
messages: Belongs to the glutamate synthase family.

516051:VC82 RS03750
gene id: 516051:VC82_RS03750
uniprot id: A0A0D5YQ36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

516051:VC82 RS05855
gene id: 516051:VC82_RS05855
uniprot id: A0A0D5YSH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

516051:VC82 RS13140
gene id: 516051:VC82_RS13140
uniprot id: A0A0D5YWD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

516051:VC82 RS06150
gene id: 516051:VC82_RS06150
uniprot id: A0A0D5YRH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

516051:VC82 RS06600
gene id: 516051:VC82_RS06600
uniprot id: A0A0D5YRQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

516051:VC82 RS03400
gene id: 516051:VC82_RS03400
uniprot id: A0A0D5YQ22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

516051:VC82 RS10830
gene id: 516051:VC82_RS10830
uniprot id: A0A0D5YV49
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS03980
gene id: 516051:VC82_RS03980
uniprot id: A0A0D5YQ78
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

516051:VC82 RS14350
gene id: 516051:VC82_RS14350
uniprot id: A0A0D5YX28
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS09515
gene id: 516051:VC82_RS09515
uniprot id: A0A0D5YUH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

516051:VC82 RS09305
gene id: 516051:VC82_RS09305
uniprot id: A0A0D5YT79
names: Similarity
messages: Belongs to the asparaginase 1 family.

516051:VC82 RS09190
gene id: 516051:VC82_RS09190
uniprot id: A0A0D5YU97
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

516051:VC82 RS12540
gene id: 516051:VC82_RS12540
uniprot id: A0A0D5YW35
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

516051:VC82 RS14210
gene id: 516051:VC82_RS14210
uniprot id: A0A0D5YVS3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

516051:VC82 RS00135
gene id: 516051:VC82_RS00135
uniprot id: A0A0D5YPG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

516051:VC82 RS05890
gene id: 516051:VC82_RS05890
uniprot id: A0A0D5YRC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS00485
gene id: 516051:VC82_RS00485
uniprot id: A0A0D5YNK1
names: Subcellular Location Annotation
messages: Secreted

516051:VC82 RS10645
gene id: 516051:VC82_RS10645
uniprot id: A0A0D5YV60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

516051:VC82 RS06470
gene id: 516051:VC82_RS06470
uniprot id: A0A0D5YSQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

516051:VC82 RS11620
gene id: 516051:VC82_RS11620
uniprot id: A0A0D5YVJ5
names: Similarity
messages: Belongs to the universal stress protein A family.

516051:VC82 RS05085
gene id: 516051:VC82_RS05085
uniprot id: A0A0D5YQZ0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

516051:VC82 RS12800
gene id: 516051:VC82_RS12800
uniprot id: A0A0D5YUZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS13570
gene id: 516051:VC82_RS13570
uniprot id: A0A0D5YVE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

516051:VC82 RS10660
gene id: 516051:VC82_RS10660
uniprot id: A0A0D5YV10
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

516051:VC82 RS04675
gene id: 516051:VC82_RS04675
uniprot id: A0A0D5YRV9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

516051:VC82 RS05770
gene id: 516051:VC82_RS05770
uniprot id: A0A0D5YRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

516051:VC82 RS01275
gene id: 516051:VC82_RS01275
uniprot id: A0A0D5YNP2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

516051:VC82 RS01370
gene id: 516051:VC82_RS01370
uniprot id: A0A0D5YQ17
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

516051:VC82 RS10960
gene id: 516051:VC82_RS10960
uniprot id: A0A0D5YV75
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS00190
gene id: 516051:VC82_RS00190
uniprot id: A0A0D5YNF0
names: Similarity
messages: Belongs to the DEAD box helicase family.

516051:VC82 RS10130
gene id: 516051:VC82_RS10130
uniprot id: A0A0D5YTS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

516051:VC82 RS09060
gene id: 516051:VC82_RS09060
uniprot id: A0A0D5YU71
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

516051:VC82 RS09030
gene id: 516051:VC82_RS09030
uniprot id: A0A0D5YT32
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

516051:VC82 RS03115
gene id: 516051:VC82_RS03115
uniprot id: A0A0D5YPY1
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

516051:VC82 RS10480
gene id: 516051:VC82_RS10480
uniprot id: A0A0D5YTQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

516051:VC82 RS15035
gene id: 516051:VC82_RS15035
uniprot id: A0A0D5YXK9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS02800
gene id: 516051:VC82_RS02800
uniprot id: A0A0D5YPT3
names: Similarity
messages: Belongs to the universal stress protein A family.

516051:VC82 RS02215
gene id: 516051:VC82_RS02215
uniprot id: A0A0D5YQG9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

516051:VC82 RS01575
gene id: 516051:VC82_RS01575
uniprot id: A0A0D5YP33
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

516051:VC82 RS04860
gene id: 516051:VC82_RS04860
uniprot id: A0A0D5YRW9
names: Similarity
messages: Belongs to the peptidase C40 family.

516051:VC82 RS02080
gene id: 516051:VC82_RS02080
uniprot id: A0A0D5YQI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

516051:VC82 RS00935
gene id: 516051:VC82_RS00935
uniprot id: A0A0D5YPW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

516051:VC82 RS05865
gene id: 516051:VC82_RS05865
uniprot id: A0A0D5YRC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

516051:VC82 RS06530
gene id: 516051:VC82_RS06530
uniprot id: A0A0D5YSX1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

516051:VC82 RS09660
gene id: 516051:VC82_RS09660
uniprot id: A0A0D5YUN1
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS09715
gene id: 516051:VC82_RS09715
uniprot id: A0A0D5YUP0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

516051:VC82 RS04960
gene id: 516051:VC82_RS04960
uniprot id: A0A0D5YQW8
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

516051:VC82 RS06130
gene id: 516051:VC82_RS06130
uniprot id: A0A0D5YSP7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

516051:VC82 RS00885
gene id: 516051:VC82_RS00885
uniprot id: A0A0D5YPV0
names: Similarity
messages: Belongs to the Dps family.

516051:VC82 RS10780
gene id: 516051:VC82_RS10780
uniprot id: A0A0D5YV39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

516051:VC82 RS04865
gene id: 516051:VC82_RS04865
uniprot id: A0A0D5YRU6
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS04165
gene id: 516051:VC82_RS04165
uniprot id: A0A0D5YRF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

516051:VC82 RS10570
gene id: 516051:VC82_RS10570
uniprot id: A0A0D5YUZ5
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS01610
gene id: 516051:VC82_RS01610
uniprot id: A0A0D5YQ03
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS12670
gene id: 516051:VC82_RS12670
uniprot id: A0A0D5YW89
names: Similarity
messages: Belongs to the SAICAR synthetase family.

516051:VC82 RS00670
gene id: 516051:VC82_RS00670
uniprot id: A0A0D5YQN9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

516051:VC82 RS04465
gene id: 516051:VC82_RS04465
uniprot id: A0A0D5YQM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

516051:VC82 RS00295
gene id: 516051:VC82_RS00295
uniprot id: A0A0D5YPD7
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

516051:VC82 RS10595
gene id: 516051:VC82_RS10595
uniprot id: A0A0D5YV00
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

516051:VC82 RS06905
gene id: 516051:VC82_RS06905
uniprot id: A0A0D5YRX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

516051:VC82 RS05725
gene id: 516051:VC82_RS05725
uniprot id: A0A0D5YSF0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

516051:VC82 RS08910
gene id: 516051:VC82_RS08910
uniprot id: A0A0D5YSW1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

516051:VC82 RS11715
gene id: 516051:VC82_RS11715
uniprot id: A0A0D5YVM8
names: Similarity
messages: Belongs to the HSP15 family.

516051:VC82 RS10445
gene id: 516051:VC82_RS10445
uniprot id: A0A0D5YTZ5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS15110
gene id: 516051:VC82_RS15110
uniprot id: A0A0D5YXM5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

516051:VC82 RS15145
gene id: 516051:VC82_RS15145
uniprot id: A0A0D5YWK4
names: Similarity
messages: Belongs to the IMPACT family.

516051:VC82 RS01290
gene id: 516051:VC82_RS01290
uniprot id: A0A0D5YNY0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

516051:VC82 RS03865
gene id: 516051:VC82_RS03865
uniprot id: A0A0D5YRD4
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS06555
gene id: 516051:VC82_RS06555
uniprot id: A0A0D5YRN3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

516051:VC82 RS15710
gene id: 516051:VC82_RS15710
uniprot id: A0A0D5YV37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

516051:VC82 RS09980
gene id: 516051:VC82_RS09980
uniprot id: A0A0D5YUP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS00060
gene id: 516051:VC82_RS00060
uniprot id: A0A0D5YNC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

516051:VC82 RS09465
gene id: 516051:VC82_RS09465
uniprot id: A0A0D5YTD5
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

516051:VC82 RS01315
gene id: 516051:VC82_RS01315
uniprot id: A0A0D5YNY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

516051:VC82 RS10690
gene id: 516051:VC82_RS10690
uniprot id: A0A0D5YTU2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

516051:VC82 RS09005
gene id: 516051:VC82_RS09005
uniprot id: A0A0D5YT29
names: Similarity
messages: Belongs to the universal stress protein A family.

516051:VC82 RS06825
gene id: 516051:VC82_RS06825
uniprot id: A0A0D5YRU7
names: Similarity
messages: Belongs to the thioredoxin family.

516051:VC82 RS00455
gene id: 516051:VC82_RS00455
uniprot id: A0A0D5YPL8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

516051:VC82 RS00925
gene id: 516051:VC82_RS00925
uniprot id: A0A0D5YPL2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

516051:VC82 RS08915
gene id: 516051:VC82_RS08915
uniprot id: A0A0D5YU74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

516051:VC82 RS00125
gene id: 516051:VC82_RS00125
uniprot id: A0A0D5YP55
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS02525
gene id: 516051:VC82_RS02525
uniprot id: A0A0D5YPE4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS02365
gene id: 516051:VC82_RS02365
uniprot id: A0A0D5YQJ3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

516051:VC82 RS12765
gene id: 516051:VC82_RS12765
uniprot id: A0A0D5YV80
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

516051:VC82 RS10005
gene id: 516051:VC82_RS10005
uniprot id: A0A0D5YUP7
names: Similarity
messages: Belongs to the Skp family.

516051:VC82 RS09950
gene id: 516051:VC82_RS09950
uniprot id: A0A0D5YTP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

516051:VC82 RS03230
gene id: 516051:VC82_RS03230
uniprot id: A0A0D5YR02
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS03800
gene id: 516051:VC82_RS03800
uniprot id: A0A0D5YQ47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

516051:VC82 RS01145
gene id: 516051:VC82_RS01145
uniprot id: A0A0D5YPZ6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

516051:VC82 RS13665
gene id: 516051:VC82_RS13665
uniprot id: A0A0D5YWL4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

516051:VC82 RS10750
gene id: 516051:VC82_RS10750
uniprot id: A0A0D5YV83
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS06215
gene id: 516051:VC82_RS06215
uniprot id: A0A0D5YSR3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS08850
gene id: 516051:VC82_RS08850
uniprot id: A0A0D5YSV2
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS00505
gene id: 516051:VC82_RS00505
uniprot id: A0A0D5YPM7
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS14420
gene id: 516051:VC82_RS14420
uniprot id: A0A0D5YX81
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

516051:VC82 RS00460
gene id: 516051:VC82_RS00460
uniprot id: A0A0D5YNJ8
names: Similarity
messages: Belongs to the group II decarboxylase family.

516051:VC82 RS05155
gene id: 516051:VC82_RS05155
uniprot id: A0A0D5YS47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS04845
gene id: 516051:VC82_RS04845
uniprot id: A0A0D5YQR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

516051:VC82 RS08250
gene id: 516051:VC82_RS08250
uniprot id: A0A0D5YTU5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS10350
gene id: 516051:VC82_RS10350
uniprot id: A0A0D5YTX3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS10055
gene id: 516051:VC82_RS10055
uniprot id: A0A0D5YTR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

516051:VC82 RS11760
gene id: 516051:VC82_RS11760
uniprot id: A0A0D5YUD8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

516051:VC82 RS00420
gene id: 516051:VC82_RS00420
uniprot id: A0A0D5YPA9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS02445
gene id: 516051:VC82_RS02445
uniprot id: A0A0D5YQH1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

516051:VC82 RS10850
gene id: 516051:VC82_RS10850
uniprot id: A0A0D5YVA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

516051:VC82 RS13835
gene id: 516051:VC82_RS13835
uniprot id: A0A0D5YWW0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

516051:VC82 RS01885
gene id: 516051:VC82_RS01885
uniprot id: A0A0D5YPC2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

516051:VC82 RS12235
gene id: 516051:VC82_RS12235
uniprot id: A0A0D5YVW6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

516051:VC82 RS12760
gene id: 516051:VC82_RS12760
uniprot id: A0A0D5YW69
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

516051:VC82 RS06305
gene id: 516051:VC82_RS06305
uniprot id: A0A0D5YRK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

516051:VC82 RS06335
gene id: 516051:VC82_RS06335
uniprot id: A0A0D5YSS1
names: Similarity
messages: Belongs to the peptidase S9A family.

516051:VC82 RS04005
gene id: 516051:VC82_RS04005
uniprot id: A0A0D5YQ80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

516051:VC82 RS07000
gene id: 516051:VC82_RS07000
uniprot id: A0A0D5YS01
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

516051:VC82 RS02825
gene id: 516051:VC82_RS02825
uniprot id: A0A0D5YPT8
names: Similarity
messages: Belongs to the universal stress protein A family.

516051:VC82 RS04330
gene id: 516051:VC82_RS04330
uniprot id: A0A0D5YRQ4
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS10460
gene id: 516051:VC82_RS10460
uniprot id: A0A0D5YV24
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS14465
gene id: 516051:VC82_RS14465
uniprot id: A0A0D5YVW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

516051:VC82 RS09315
gene id: 516051:VC82_RS09315
uniprot id: A0A0D5YUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

516051:VC82 RS11565
gene id: 516051:VC82_RS11565
uniprot id: A0A0D5YVI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

516051:VC82 RS04745
gene id: 516051:VC82_RS04745
uniprot id: A0A0D5YQP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

516051:VC82 RS07920
gene id: 516051:VC82_RS07920
uniprot id: A0A0D5YTN2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

516051:VC82 RS05905
gene id: 516051:VC82_RS05905
uniprot id: A0A0D5YSI6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

516051:VC82 RS10410
gene id: 516051:VC82_RS10410
uniprot id: A0A0D5YV12
names: Similarity
messages: Belongs to the pirin family.

516051:VC82 RS10310
gene id: 516051:VC82_RS10310
uniprot id: A0A0D5YTM2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

516051:VC82 RS03725
gene id: 516051:VC82_RS03725
uniprot id: A0A0D5YQ32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

516051:VC82 RS04775
gene id: 516051:VC82_RS04775
uniprot id: A0A0D5YRX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

516051:VC82 RS10820
gene id: 516051:VC82_RS10820
uniprot id: A0A0D5YTW4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

516051:VC82 RS01000
gene id: 516051:VC82_RS01000
uniprot id: A0A0D5YPT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

516051:VC82 RS02240
gene id: 516051:VC82_RS02240
uniprot id: A0A0D5YQL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

516051:VC82 RS05620
gene id: 516051:VC82_RS05620
uniprot id: A0A0D5YSD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

516051:VC82 RS01825
gene id: 516051:VC82_RS01825
uniprot id: A0A0D5YP21
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

516051:VC82 RS14095
gene id: 516051:VC82_RS14095
uniprot id: A0A0D5YWX9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

516051:VC82 RS01265
gene id: 516051:VC82_RS01265
uniprot id: A0A0D5YPZ5
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS12835
gene id: 516051:VC82_RS12835
uniprot id: A0A0D5YW83
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

516051:VC82 RS13075
gene id: 516051:VC82_RS13075
uniprot id: A0A0D5YWA0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

516051:VC82 RS04080
gene id: 516051:VC82_RS04080
uniprot id: A0A0D5YRD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

516051:VC82 RS00245
gene id: 516051:VC82_RS00245
uniprot id: A0A0D5YPC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

516051:VC82 RS00425
gene id: 516051:VC82_RS00425
uniprot id: A0A0D5YN80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

516051:VC82 RS07805
gene id: 516051:VC82_RS07805
uniprot id: A0A0D5YSG1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

516051:VC82 RS11955
gene id: 516051:VC82_RS11955
uniprot id: A0A0D5YVR9
names: Similarity
messages: Belongs to the BshC family.

516051:VC82 RS13355
gene id: 516051:VC82_RS13355
uniprot id: A0A0D5YWF3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

516051:VC82 RS14720
gene id: 516051:VC82_RS14720
uniprot id: A0A0D5YXA1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

516051:VC82 RS03730
gene id: 516051:VC82_RS03730
uniprot id: A0A0D5YRD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

516051:VC82 RS08635
gene id: 516051:VC82_RS08635
uniprot id: A0A0D5YTZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

516051:VC82 RS00275
gene id: 516051:VC82_RS00275
uniprot id: A0A0D5YP79
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS09185
gene id: 516051:VC82_RS09185
uniprot id: A0A0D5YT55
names: Similarity
messages: Belongs to the universal stress protein A family.

516051:VC82 RS00470
gene id: 516051:VC82_RS00470
uniprot id: A0A0D5YPB8
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.

516051:VC82 RS07040
gene id: 516051:VC82_RS07040
uniprot id: A0A0D5YT67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

516051:VC82 RS05450
gene id: 516051:VC82_RS05450
uniprot id: A0A0D5YS90
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

516051:VC82 RS05860
gene id: 516051:VC82_RS05860
uniprot id: A0A0D5YSD2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

516051:VC82 RS10630
gene id: 516051:VC82_RS10630
uniprot id: A0A0D5YU29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

516051:VC82 RS15025
gene id: 516051:VC82_RS15025
uniprot id: A0A0D5YXE8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

516051:VC82 RS14585
gene id: 516051:VC82_RS14585
uniprot id: A0A0D5YX56
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS05115
gene id: 516051:VC82_RS05115
uniprot id: A0A0D5YS23
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS06230
gene id: 516051:VC82_RS06230
uniprot id: A0A0D5YSK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

516051:VC82 RS03810
gene id: 516051:VC82_RS03810
uniprot id: A0A0D5YQ86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

516051:VC82 RS10845
gene id: 516051:VC82_RS10845
uniprot id: A0A0D5YTW9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS06640
gene id: 516051:VC82_RS06640
uniprot id: A0A0D5YRQ2
names: Similarity
messages: Belongs to the Skp family.

516051:VC82 RS04090
gene id: 516051:VC82_RS04090
uniprot id: A0A0D5YQ94
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

516051:VC82 RS05600
gene id: 516051:VC82_RS05600
uniprot id: A0A0D5YS83
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

516051:VC82 RS02700
gene id: 516051:VC82_RS02700
uniprot id: A0A0D5YPR5
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS10640
gene id: 516051:VC82_RS10640
uniprot id: A0A0D5YTT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

516051:VC82 RS02115
gene id: 516051:VC82_RS02115
uniprot id: A0A0D5YQF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

516051:VC82 RS08145
gene id: 516051:VC82_RS08145
uniprot id: A0A0D5YTS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

516051:VC82 RS15825
gene id: 516051:VC82_RS15825
uniprot id: A0A0D5YUM3
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS02020
gene id: 516051:VC82_RS02020
uniprot id: A0A0D5YQA0
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS05165
gene id: 516051:VC82_RS05165
uniprot id: A0A0D5YS34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

516051:VC82 RS08965
gene id: 516051:VC82_RS08965
uniprot id: A0A0D5YSX0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

516051:VC82 RS07285
gene id: 516051:VC82_RS07285
uniprot id: A0A0D5YTB1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

516051:VC82 RS12200
gene id: 516051:VC82_RS12200
uniprot id: A0A0D5YVY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS06525
gene id: 516051:VC82_RS06525
uniprot id: A0A0D5YRM9
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS02325
gene id: 516051:VC82_RS02325
uniprot id: A0A0D5YQM7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

516051:VC82 RS11235
gene id: 516051:VC82_RS11235
uniprot id: A0A0D5YUE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

516051:VC82 RS02935
gene id: 516051:VC82_RS02935
uniprot id: A0A0D5YQR2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

516051:VC82 RS05420
gene id: 516051:VC82_RS05420
uniprot id: A0A0D5YS85
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

516051:VC82 RS12515
gene id: 516051:VC82_RS12515
uniprot id: A0A0D5YW31
names: Similarity
messages: Belongs to the polysaccharide synthase family.

516051:VC82 RS04450
gene id: 516051:VC82_RS04450
uniprot id: A0A0D5YRM4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

516051:VC82 RS03010
gene id: 516051:VC82_RS03010
uniprot id: A0A0D5YPW7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

516051:VC82 RS04305
gene id: 516051:VC82_RS04305
uniprot id: A0A0D5YRP9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

516051:VC82 RS04370
gene id: 516051:VC82_RS04370
uniprot id: A0A0D5YRL2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

516051:VC82 RS02420
gene id: 516051:VC82_RS02420
uniprot id: A0A0D5YQG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

516051:VC82 RS06500
gene id: 516051:VC82_RS06500
uniprot id: A0A0D5YRM5
names: Similarity
messages: Belongs to the peptidase S41A family.

516051:VC82 RS03660
gene id: 516051:VC82_RS03660
uniprot id: A0A0D5YQ64
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

516051:VC82 RS02485
gene id: 516051:VC82_RS02485
uniprot id: A0A0D5YPM9
names: Similarity
messages: Belongs to the P(II) protein family.

516051:VC82 RS05160
gene id: 516051:VC82_RS05160
uniprot id: A0A0D5YR04
names: Similarity
messages: Belongs to the SusD family.

516051:VC82 RS03415
gene id: 516051:VC82_RS03415
uniprot id: A0A0D5YPX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

516051:VC82 RS03210
gene id: 516051:VC82_RS03210
uniprot id: A0A0D5YQW3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

516051:VC82 RS13435
gene id: 516051:VC82_RS13435
uniprot id: A0A0D5YVC2
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS03700
gene id: 516051:VC82_RS03700
uniprot id: A0A0D5YQ27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

516051:VC82 RS01655
gene id: 516051:VC82_RS01655
uniprot id: A0A0D5YP72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

516051:VC82 RS03685
gene id: 516051:VC82_RS03685
uniprot id: A0A0D5YQ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

516051:VC82 RS11585
gene id: 516051:VC82_RS11585
uniprot id: A0A0D5YUJ4
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

516051:VC82 RS13485
gene id: 516051:VC82_RS13485
uniprot id: A0A0D5YVL6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS08940
gene id: 516051:VC82_RS08940
uniprot id: A0A0D5YSW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

516051:VC82 RS10635
gene id: 516051:VC82_RS10635
uniprot id: A0A0D5YV05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

516051:VC82 RS10925
gene id: 516051:VC82_RS10925
uniprot id: A0A0D5YTY7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

516051:VC82 RS04735
gene id: 516051:VC82_RS04735
uniprot id: A0A0D5YRV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

516051:VC82 RS01270
gene id: 516051:VC82_RS01270
uniprot id: A0A0D5YPT0
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS09705
gene id: 516051:VC82_RS09705
uniprot id: A0A0D5YUK3
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS10650
gene id: 516051:VC82_RS10650
uniprot id: A0A0D5YV11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

516051:VC82 RS10525
gene id: 516051:VC82_RS10525
uniprot id: A0A0D5YU10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

516051:VC82 RS12505
gene id: 516051:VC82_RS12505
uniprot id: A0A0D5YUU8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

516051:VC82 RS07010
gene id: 516051:VC82_RS07010
uniprot id: A0A0D5YRZ1
names: Similarity
messages: Belongs to the DprA/Smf family.

516051:VC82 RS11605
gene id: 516051:VC82_RS11605
uniprot id: A0A0D5YVP2
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS14510
gene id: 516051:VC82_RS14510
uniprot id: A0A0D5YX42
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

516051:VC82 RS06395
gene id: 516051:VC82_RS06395
uniprot id: A0A0D5YSP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

516051:VC82 RS08570
gene id: 516051:VC82_RS08570
uniprot id: A0A0D5YTX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

516051:VC82 RS00075
gene id: 516051:VC82_RS00075
uniprot id: A0A0D5YN09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS05740
gene id: 516051:VC82_RS05740
uniprot id: A0A0D5YSG8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

516051:VC82 RS12285
gene id: 516051:VC82_RS12285
uniprot id: A0A0D5YVX2
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS08380
gene id: 516051:VC82_RS08380
uniprot id: A0A0D5YTT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

516051:VC82 RS00555
gene id: 516051:VC82_RS00555
uniprot id: A0A0D5YPN9
names: Similarity
messages: Belongs to the peptidase M16 family.

516051:VC82 RS03745
gene id: 516051:VC82_RS03745
uniprot id: A0A0D5YR74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

516051:VC82 RS03525
gene id: 516051:VC82_RS03525
uniprot id: A0A0D5YPZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS11785
gene id: 516051:VC82_RS11785
uniprot id: A0A0D5YUE3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

516051:VC82 RS12815
gene id: 516051:VC82_RS12815
uniprot id: A0A0D5YV89
names: Similarity
messages: Belongs to the pirin family.

516051:VC82 RS14970
gene id: 516051:VC82_RS14970
uniprot id: A0A0D5YWG7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

516051:VC82 RS13100
gene id: 516051:VC82_RS13100
uniprot id: A0A0D5YWA4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

516051:VC82 RS07550
gene id: 516051:VC82_RS07550
uniprot id: A0A0D5YSB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

516051:VC82 RS08320
gene id: 516051:VC82_RS08320
uniprot id: A0A0D5YSL3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

516051:VC82 RS01565
gene id: 516051:VC82_RS01565
uniprot id: A0A0D5YNU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

516051:VC82 RS04790
gene id: 516051:VC82_RS04790
uniprot id: A0A0D5YRS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS00025
gene id: 516051:VC82_RS00025
uniprot id: A0A0D5YMZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

516051:VC82 RS03775
gene id: 516051:VC82_RS03775
uniprot id: A0A0D5YQ40
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

516051:VC82 RS13760
gene id: 516051:VC82_RS13760
uniprot id: A0A0D5YWQ8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

516051:VC82 RS07640
gene id: 516051:VC82_RS07640
uniprot id: A0A0D5YSA5
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS05990
gene id: 516051:VC82_RS05990
uniprot id: A0A0D5YRE7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

516051:VC82 RS03295
gene id: 516051:VC82_RS03295
uniprot id: A0A0D5YQX7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

516051:VC82 RS06315
gene id: 516051:VC82_RS06315
uniprot id: A0A0D5YSM5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS11930
gene id: 516051:VC82_RS11930
uniprot id: A0A0D5YUP9
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

516051:VC82 RS11430
gene id: 516051:VC82_RS11430
uniprot id: A0A0D5YUG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

516051:VC82 RS09220
gene id: 516051:VC82_RS09220
uniprot id: A0A0D5YUD4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

516051:VC82 RS11295
gene id: 516051:VC82_RS11295
uniprot id: A0A0D5YVC9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

516051:VC82 RS02425
gene id: 516051:VC82_RS02425
uniprot id: A0A0D5YPC5
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS10015
gene id: 516051:VC82_RS10015
uniprot id: A0A0D5YUU1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

516051:VC82 RS11080
gene id: 516051:VC82_RS11080
uniprot id: A0A0D5YVA3
names: Similarity
messages: Belongs to the nitroreductase family.

516051:VC82 RS02005
gene id: 516051:VC82_RS02005
uniprot id: A0A0D5YQG8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

516051:VC82 RS09945
gene id: 516051:VC82_RS09945
uniprot id: A0A0D5YUN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

516051:VC82 RS12660
gene id: 516051:VC82_RS12660
uniprot id: A0A0D5YW28
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

516051:VC82 RS05050
gene id: 516051:VC82_RS05050
uniprot id: A0A0D5YQV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

516051:VC82 RS08985
gene id: 516051:VC82_RS08985
uniprot id: A0A0D5YU56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

516051:VC82 RS02015
gene id: 516051:VC82_RS02015
uniprot id: A0A0D5YQE2
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS09605
gene id: 516051:VC82_RS09605
uniprot id: A0A0D5YTA5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

516051:VC82 RS04815
gene id: 516051:VC82_RS04815
uniprot id: A0A0D5YRT5
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

516051:VC82 RS03760
gene id: 516051:VC82_RS03760
uniprot id: A0A0D5YQ77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

516051:VC82 RS07870
gene id: 516051:VC82_RS07870
uniprot id: A0A0D5YTM0
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

516051:VC82 RS11870
gene id: 516051:VC82_RS11870
uniprot id: A0A0D5YVT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

516051:VC82 RS14335
gene id: 516051:VC82_RS14335
uniprot id: A0A0D5YX04
names: Similarity
messages: Belongs to the LOG family.

516051:VC82 RS10575
gene id: 516051:VC82_RS10575
uniprot id: A0A0D5YU21
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

516051:VC82 RS01245
gene id: 516051:VC82_RS01245
uniprot id: A0A0D5YPS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

516051:VC82 RS11920
gene id: 516051:VC82_RS11920
uniprot id: A0A0D5YVU3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

516051:VC82 RS14790
gene id: 516051:VC82_RS14790
uniprot id: A0A0D5YWD1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

516051:VC82 RS04765
gene id: 516051:VC82_RS04765
uniprot id: A0A0D5YRS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

516051:VC82 RS07540
gene id: 516051:VC82_RS07540
uniprot id: A0A0D5YTF4
names: Similarity
messages: Belongs to the peptidase S41A family.

516051:VC82 RS08600
gene id: 516051:VC82_RS08600
uniprot id: A0A0D5YSW4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

516051:VC82 RS08295
gene id: 516051:VC82_RS08295
uniprot id: A0A0D5YSK8
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS07465
gene id: 516051:VC82_RS07465
uniprot id: A0A0D5YTD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

516051:VC82 RS02830
gene id: 516051:VC82_RS02830
uniprot id: A0A0D5YQS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

516051:VC82 RS12860
gene id: 516051:VC82_RS12860
uniprot id: A0A0D5YW87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

516051:VC82 RS00790
gene id: 516051:VC82_RS00790
uniprot id: A0A0D5YPI6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS11210
gene id: 516051:VC82_RS11210
uniprot id: A0A0D5YUD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

516051:VC82 RS02615
gene id: 516051:VC82_RS02615
uniprot id: A0A0D5YPQ0
names: Similarity
messages: Belongs to the glutamine synthetase family.

516051:VC82 RS07070
gene id: 516051:VC82_RS07070
uniprot id: A0A0D5YT41
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

516051:VC82 RS00240
gene id: 516051:VC82_RS00240
uniprot id: A0A0D5YNG0
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

516051:VC82 RS10810
gene id: 516051:VC82_RS10810
uniprot id: A0A0D5YU63
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

516051:VC82 RS02770
gene id: 516051:VC82_RS02770
uniprot id: A0A0D5YQW1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

516051:VC82 RS12460
gene id: 516051:VC82_RS12460
uniprot id: A0A0D5YW53
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

516051:VC82 RS10365
gene id: 516051:VC82_RS10365
uniprot id: A0A0D5YUV9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

516051:VC82 RS07475
gene id: 516051:VC82_RS07475
uniprot id: A0A0D5YS96
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

516051:VC82 RS10010
gene id: 516051:VC82_RS10010
uniprot id: A0A0D5YTH1
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

516051:VC82 RS12355
gene id: 516051:VC82_RS12355
uniprot id: A0A0D5YW07
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS02980
gene id: 516051:VC82_RS02980
uniprot id: A0A0D5YQZ7
names: Similarity
messages: Belongs to the archease family.

516051:VC82 RS06920
gene id: 516051:VC82_RS06920
uniprot id: A0A0D5YRY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

516051:VC82 RS07855
gene id: 516051:VC82_RS07855
uniprot id: A0A0D5YSH2
names: Similarity
messages: Belongs to the peptidase S9C family.

516051:VC82 RS09175
gene id: 516051:VC82_RS09175
uniprot id: A0A0D5YUC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

516051:VC82 RS06850
gene id: 516051:VC82_RS06850
uniprot id: A0A0D5YRV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

516051:VC82 RS15120
gene id: 516051:VC82_RS15120
uniprot id: A0A0D5YWJ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

516051:VC82 RS11190
gene id: 516051:VC82_RS11190
uniprot id: A0A0D5YVB0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

516051:VC82 RS02550
gene id: 516051:VC82_RS02550
uniprot id: A0A0D5YPE8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

516051:VC82 RS04835
gene id: 516051:VC82_RS04835
uniprot id: A0A0D5YRW6
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

516051:VC82 RS03250
gene id: 516051:VC82_RS03250
uniprot id: A0A0D5YQ02
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

516051:VC82 RS12250
gene id: 516051:VC82_RS12250
uniprot id: A0A0D5YVZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

516051:VC82 RS11300
gene id: 516051:VC82_RS11300
uniprot id: A0A0D5YU55
names: Cofactor
messages: Binds 1 zinc ion per subunit.

516051:VC82 RS14100
gene id: 516051:VC82_RS14100
uniprot id: A0A0D5YVX4
names: Similarity
messages: Belongs to the SUI1 family.

516051:VC82 RS04160
gene id: 516051:VC82_RS04160
uniprot id: A0A0D5YRI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

516051:VC82 RS08365
gene id: 516051:VC82_RS08365
uniprot id: A0A0D5YTV2
names: Similarity
messages: Belongs to the ribF family.

516051:VC82 RS06705
gene id: 516051:VC82_RS06705
uniprot id: A0A0D5YSZ6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

516051:VC82 RS03795
gene id: 516051:VC82_RS03795
uniprot id: A0A0D5YR84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

516051:VC82 RS03275
gene id: 516051:VC82_RS03275
uniprot id: A0A0D5YPT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS10670
gene id: 516051:VC82_RS10670
uniprot id: A0A0D5YV65
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

516051:VC82 RS09860
gene id: 516051:VC82_RS09860
uniprot id: A0A0D5YUM5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

516051:VC82 RS08430
gene id: 516051:VC82_RS08430
uniprot id: A0A0D5YTX9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

516051:VC82 RS06350
gene id: 516051:VC82_RS06350
uniprot id: A0A0D5YRK1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

516051:VC82 RS02060
gene id: 516051:VC82_RS02060
uniprot id: A0A0D5YPF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

516051:VC82 RS06940
gene id: 516051:VC82_RS06940
uniprot id: A0A0D5YT50
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS09630
gene id: 516051:VC82_RS09630
uniprot id: A0A0D5YTB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

516051:VC82 RS05645
gene id: 516051:VC82_RS05645
uniprot id: A0A0D5YSD5
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS07435
gene id: 516051:VC82_RS07435
uniprot id: A0A0D5YS66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

516051:VC82 RS13235
gene id: 516051:VC82_RS13235
uniprot id: A0A0D5YV82
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS01395
gene id: 516051:VC82_RS01395
uniprot id: A0A0D5YQ21
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

516051:VC82 RS10340
gene id: 516051:VC82_RS10340
uniprot id: A0A0D5YUZ9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

516051:VC82 RS13650
gene id: 516051:VC82_RS13650
uniprot id: A0A0D5YWS6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

516051:VC82 RS08725
gene id: 516051:VC82_RS08725
uniprot id: A0A0D5YU04
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS11200
gene id: 516051:VC82_RS11200
uniprot id: A0A0D5YVG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

516051:VC82 RS03805
gene id: 516051:VC82_RS03805
uniprot id: A0A0D5YRE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

516051:VC82 RS03450
gene id: 516051:VC82_RS03450
uniprot id: A0A0D5YQ30
names: Similarity
messages: Belongs to the SusD family.

516051:VC82 RS02580
gene id: 516051:VC82_RS02580
uniprot id: A0A0D5YQS6
names: Similarity
messages: Belongs to the AIR synthase family.

516051:VC82 RS09710
gene id: 516051:VC82_RS09710
uniprot id: A0A0D5YTC2
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS00585
gene id: 516051:VC82_RS00585
uniprot id: A0A0D5YNL7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

516051:VC82 RS10375
gene id: 516051:VC82_RS10375
uniprot id: A0A0D5YUV8
names: Similarity
messages: Belongs to the NAD synthetase family.

516051:VC82 RS05105
gene id: 516051:VC82_RS05105
uniprot id: A0A0D5YS38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

516051:VC82 RS05395
gene id: 516051:VC82_RS05395
uniprot id: A0A0D5YS80
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

516051:VC82 RS14715
gene id: 516051:VC82_RS14715
uniprot id: A0A0D5YWB1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

516051:VC82 RS05880
gene id: 516051:VC82_RS05880
uniprot id: A0A0D5YSI0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

516051:VC82 RS09410
gene id: 516051:VC82_RS09410
uniprot id: A0A0D5YUE0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

516051:VC82 RS04240
gene id: 516051:VC82_RS04240
uniprot id: A0A0D5YRJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

516051:VC82 RS10940
gene id: 516051:VC82_RS10940
uniprot id: A0A0D5YU90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

516051:VC82 RS12775
gene id: 516051:VC82_RS12775
uniprot id: A0A0D5YUZ3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

516051:VC82 RS07690
gene id: 516051:VC82_RS07690
uniprot id: A0A0D5YSB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

516051:VC82 RS01890
gene id: 516051:VC82_RS01890
uniprot id: A0A0D5YQC4
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

516051:VC82 RS04170
gene id: 516051:VC82_RS04170
uniprot id: A0A0D5YQA8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

516051:VC82 RS11980
gene id: 516051:VC82_RS11980
uniprot id: A0A0D5YVS4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

516051:VC82 RS03675
gene id: 516051:VC82_RS03675
uniprot id: A0A0D5YQ23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

516051:VC82 RS10170
gene id: 516051:VC82_RS10170
uniprot id: A0A0D5YUW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

516051:VC82 RS09140
gene id: 516051:VC82_RS09140
uniprot id: A0A0D5YU87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS05605
gene id: 516051:VC82_RS05605
uniprot id: A0A0D5YR65
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

516051:VC82 RS01380
gene id: 516051:VC82_RS01380
uniprot id: A0A0D5YNQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

516051:VC82 RS04410
gene id: 516051:VC82_RS04410
uniprot id: A0A0D5YQL4
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

516051:VC82 RS06485
gene id: 516051:VC82_RS06485
uniprot id: A0A0D5YRN5
names: Similarity
messages: Belongs to the peptidase S8 family.

516051:VC82 RS12770
gene id: 516051:VC82_RS12770
uniprot id: A0A0D5YW45
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

516051:VC82 RS12740
gene id: 516051:VC82_RS12740
uniprot id: A0A0D5YW40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS06720
gene id: 516051:VC82_RS06720
uniprot id: A0A0D5YT01
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

516051:VC82 RS06490
gene id: 516051:VC82_RS06490
uniprot id: A0A0D5YSV5
names: Cofactor
messages: Binds 1 zinc ion per subunit.

516051:VC82 RS10540
gene id: 516051:VC82_RS10540
uniprot id: A0A0D5YV38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

516051:VC82 RS09695
gene id: 516051:VC82_RS09695
uniprot id: A0A0D5YTJ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

516051:VC82 RS06250
gene id: 516051:VC82_RS06250
uniprot id: A0A0D5YRK2
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS13615
gene id: 516051:VC82_RS13615
uniprot id: A0A0D5YWK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

516051:VC82 RS04605
gene id: 516051:VC82_RS04605
uniprot id: A0A0D5YQQ0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

516051:VC82 RS06620
gene id: 516051:VC82_RS06620
uniprot id: A0A0D5YSY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

516051:VC82 RS10345
gene id: 516051:VC82_RS10345
uniprot id: A0A0D5YUV5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

516051:VC82 RS00010
gene id: 516051:VC82_RS00010
uniprot id: A0A0D5YNB9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

516051:VC82 RS14945
gene id: 516051:VC82_RS14945
uniprot id: A0A0D5YWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

516051:VC82 RS00490
gene id: 516051:VC82_RS00490
uniprot id: A0A0D5YPI0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

516051:VC82 RS10855
gene id: 516051:VC82_RS10855
uniprot id: A0A0D5YV53
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

516051:VC82 RS12995
gene id: 516051:VC82_RS12995
uniprot id: A0A0D5YVC1
names: Similarity
messages: Belongs to the CvfB family.

516051:VC82 RS08505
gene id: 516051:VC82_RS08505
uniprot id: A0A0D5YQN9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

516051:VC82 RS07495
gene id: 516051:VC82_RS07495
uniprot id: A0A0D5YTB8
names: Similarity
messages: Belongs to the group II decarboxylase family.

516051:VC82 RS02195
gene id: 516051:VC82_RS02195
uniprot id: A0A0D5YQD1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

516051:VC82 RS00495
gene id: 516051:VC82_RS00495
uniprot id: A0A0D5YPC3
names: PTM
messages: Binds 1 heme c group covalently per subunit.

516051:VC82 RS01365
gene id: 516051:VC82_RS01365
uniprot id: A0A0D5YNZ4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

516051:VC82 RS09425
gene id: 516051:VC82_RS09425
uniprot id: A0A0D5YT40
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

516051:VC82 RS05945
gene id: 516051:VC82_RS05945
uniprot id: A0A0D5YSL0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

516051:VC82 RS06960
gene id: 516051:VC82_RS06960
uniprot id: A0A0D5YRY2
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS09690
gene id: 516051:VC82_RS09690
uniprot id: A0A0D5YUJ8
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS06015
gene id: 516051:VC82_RS06015
uniprot id: A0A0D5YRF2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

516051:VC82 RS12895
gene id: 516051:VC82_RS12895
uniprot id: A0A0D5YW68
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS00390
gene id: 516051:VC82_RS00390
uniprot id: A0A0D5YPF9
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS09430
gene id: 516051:VC82_RS09430
uniprot id: A0A0D5YUG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

516051:VC82 RS03720
gene id: 516051:VC82_RS03720
uniprot id: A0A0D5YR68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

516051:VC82 RS03735
gene id: 516051:VC82_RS03735
uniprot id: A0A0D5YQ76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

516051:VC82 RS06715
gene id: 516051:VC82_RS06715
uniprot id: A0A0D5YRR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

516051:VC82 RS09360
gene id: 516051:VC82_RS09360
uniprot id: A0A0D5YT90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

516051:VC82 RS10590
gene id: 516051:VC82_RS10590
uniprot id: A0A0D5YV48
names: Similarity
messages: Belongs to the DinB family.

516051:VC82 RS02395
gene id: 516051:VC82_RS02395
uniprot id: A0A0D5YQG1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

516051:VC82 RS06220
gene id: 516051:VC82_RS06220
uniprot id: A0A0D5YRJ8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

516051:VC82 RS06710
gene id: 516051:VC82_RS06710
uniprot id: A0A0D5YSV3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

516051:VC82 RS12185
gene id: 516051:VC82_RS12185
uniprot id: A0A0D5YVV9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

516051:VC82 RS12070
gene id: 516051:VC82_RS12070
uniprot id: A0A0D5YUI6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

516051:VC82 RS02645
gene id: 516051:VC82_RS02645
uniprot id: A0A0D5YQP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

516051:VC82 RS07605
gene id: 516051:VC82_RS07605
uniprot id: A0A0D5YSC4
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

516051:VC82 RS10120
gene id: 516051:VC82_RS10120
uniprot id: A0A0D5YUV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

516051:VC82 RS01045
gene id: 516051:VC82_RS01045
uniprot id: A0A0D5YQN9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

516051:VC82 RS04525
gene id: 516051:VC82_RS04525
uniprot id: A0A0D5YPY1
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

516051:VC82 RS02440
gene id: 516051:VC82_RS02440
uniprot id: A0A0D5YQK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

516051:VC82 RS10335
gene id: 516051:VC82_RS10335
uniprot id: A0A0D5YTM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

516051:VC82 RS05560
gene id: 516051:VC82_RS05560
uniprot id: A0A0D5YSC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

516051:VC82 RS09520
gene id: 516051:VC82_RS09520
uniprot id: A0A0D5YTF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

516051:VC82 RS04830
gene id: 516051:VC82_RS04830
uniprot id: A0A0D5YQU3
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS09650
gene id: 516051:VC82_RS09650
uniprot id: A0A0D5YUJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

516051:VC82 RS05535
gene id: 516051:VC82_RS05535
uniprot id: A0A0D5YSC3
names: Similarity
messages: Belongs to the UPF0045 family.

516051:VC82 RS03445
gene id: 516051:VC82_RS03445
uniprot id: A0A0D5YR80
names: Subunit
messages: Monomer.

516051:VC82 RS02000
gene id: 516051:VC82_RS02000
uniprot id: A0A0D5YP53
names: Similarity
messages: Belongs to the aldose epimerase family.

516051:VC82 RS03790
gene id: 516051:VC82_RS03790
uniprot id: A0A0D5YRB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

516051:VC82 RS03495
gene id: 516051:VC82_RS03495
uniprot id: A0A0D5YR22
names: Subcellular Location Annotation
messages: Membrane

516051:VC82 RS00005
gene id: 516051:VC82_RS00005
uniprot id: A0A0D5YPD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

516051:VC82 RS11040
gene id: 516051:VC82_RS11040
uniprot id: A0A0D5YV84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

516051:VC82 RS10070
gene id: 516051:VC82_RS10070
uniprot id: A0A0D5YUU9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

516051:VC82 RS01385
gene id: 516051:VC82_RS01385
uniprot id: A0A0D5YQ35
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

516051:VC82 RS11900
gene id: 516051:VC82_RS11900
uniprot id: A0A0D5YVQ8
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

516051:VC82 RS12645
gene id: 516051:VC82_RS12645
uniprot id: A0A0D5YW85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.