509193:THEBR RS04445
gene id: 509193:THEBR_RS04445
uniprot id: E8URF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

509193:THEBR RS06745
gene id: 509193:THEBR_RS06745
uniprot id: E8UTU7
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

509193:THEBR RS00075
gene id: 509193:THEBR_RS00075
uniprot id: E8USW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

509193:THEBR RS02650
gene id: 509193:THEBR_RS02650
uniprot id: E8UVQ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

509193:THEBR RS06180
gene id: 509193:THEBR_RS06180
uniprot id: E8UT31
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS03225
gene id: 509193:THEBR_RS03225
uniprot id: E8UW90
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

509193:THEBR RS05815
gene id: 509193:THEBR_RS05815
uniprot id: E8USS6
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

509193:THEBR RS05800
gene id: 509193:THEBR_RS05800
uniprot id: E8USS3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

509193:THEBR RS01055
gene id: 509193:THEBR_RS01055
uniprot id: E8UU29
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

509193:THEBR RS01070
gene id: 509193:THEBR_RS01070
uniprot id: E8UU33
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS00255
gene id: 509193:THEBR_RS00255
uniprot id: E8URH0
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

509193:THEBR RS11460
gene id: 509193:THEBR_RS11460
uniprot id: E8USI9
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS08735
gene id: 509193:THEBR_RS08735
uniprot id: E8UVW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

509193:THEBR RS08705
gene id: 509193:THEBR_RS08705
uniprot id: E8UVW2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

509193:THEBR RS06730
gene id: 509193:THEBR_RS06730
uniprot id: E8UTU4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS02260
gene id: 509193:THEBR_RS02260
uniprot id: E8UVB4
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

509193:THEBR RS01095
gene id: 509193:THEBR_RS01095
uniprot id: E8UU38
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

509193:THEBR RS05275
gene id: 509193:THEBR_RS05275
uniprot id: E8USB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS00040
gene id: 509193:THEBR_RS00040
uniprot id: E8USV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

509193:THEBR RS08255
gene id: 509193:THEBR_RS08255
uniprot id: E8UVG3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

509193:THEBR RS09555
gene id: 509193:THEBR_RS09555
uniprot id: E8UWS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS11455
gene id: 509193:THEBR_RS11455
uniprot id: E8USI8
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

509193:THEBR RS09325
gene id: 509193:THEBR_RS09325
uniprot id: E8UWF9
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS02670
gene id: 509193:THEBR_RS02670
uniprot id: E8UVQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

509193:THEBR RS01705
gene id: 509193:THEBR_RS01705
uniprot id: E8UUM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

509193:THEBR RS06920
gene id: 509193:THEBR_RS06920
uniprot id: E8UTX7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

509193:THEBR RS00825
gene id: 509193:THEBR_RS00825
uniprot id: E8UTR2
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

509193:THEBR RS09615
gene id: 509193:THEBR_RS09615
uniprot id: E8UWT4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

509193:THEBR RS08355
gene id: 509193:THEBR_RS08355
uniprot id: E8UVI1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

509193:THEBR RS02000
gene id: 509193:THEBR_RS02000
uniprot id: E8UV04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

509193:THEBR RS00340
gene id: 509193:THEBR_RS00340
uniprot id: E8UT92
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS04865
gene id: 509193:THEBR_RS04865
uniprot id: E8URV9
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS06300
gene id: 509193:THEBR_RS06300
uniprot id: E8UT55
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

509193:THEBR RS06150
gene id: 509193:THEBR_RS06150
uniprot id: E8UT25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

509193:THEBR RS05525
gene id: 509193:THEBR_RS05525
uniprot id: E8USG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

509193:THEBR RS06130
gene id: 509193:THEBR_RS06130
uniprot id: E8UT21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

509193:THEBR RS01170
gene id: 509193:THEBR_RS01170
uniprot id: E8UU52
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS06480
gene id: 509193:THEBR_RS06480
uniprot id: E8UTH0
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

509193:THEBR RS04550
gene id: 509193:THEBR_RS04550
uniprot id: E8URH3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS09410
gene id: 509193:THEBR_RS09410
uniprot id: E8UWP8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

509193:THEBR RS08740
gene id: 509193:THEBR_RS08740
uniprot id: E8UVW9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

509193:THEBR RS05575
gene id: 509193:THEBR_RS05575
uniprot id: E8USM7
names: Similarity
messages: Belongs to the asp23 family.

509193:THEBR RS07280
gene id: 509193:THEBR_RS07280
uniprot id: E8UUC0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

509193:THEBR RS06570
gene id: 509193:THEBR_RS06570
uniprot id: E8UTI8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

509193:THEBR RS08890
gene id: 509193:THEBR_RS08890
uniprot id: E8UW00
names: Similarity
messages: Belongs to the carbamate kinase family.

509193:THEBR RS08035
gene id: 509193:THEBR_RS08035
uniprot id: E8UV56
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

509193:THEBR RS02725
gene id: 509193:THEBR_RS02725
uniprot id: E8UVR6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

509193:THEBR RS02510
gene id: 509193:THEBR_RS02510
uniprot id: E8UVM3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS03005
gene id: 509193:THEBR_RS03005
uniprot id: E8UW47
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

509193:THEBR RS11370
gene id: 509193:THEBR_RS11370
uniprot id: E8USH2
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

509193:THEBR RS00155
gene id: 509193:THEBR_RS00155
uniprot id: E8USX4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

509193:THEBR RS00695
gene id: 509193:THEBR_RS00695
uniprot id: E8UTN9
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

509193:THEBR RS06235
gene id: 509193:THEBR_RS06235
uniprot id: E8UT42
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

509193:THEBR RS02620
gene id: 509193:THEBR_RS02620
uniprot id: E8UVP5
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS00830
gene id: 509193:THEBR_RS00830
uniprot id: E8UTR3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS07290
gene id: 509193:THEBR_RS07290
uniprot id: E8UUC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

509193:THEBR RS00710
gene id: 509193:THEBR_RS00710
uniprot id: E8UTP2
names: Similarity
messages: Belongs to the UPF0735 family.

509193:THEBR RS04785
gene id: 509193:THEBR_RS04785
uniprot id: E8URL7
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS03080
gene id: 509193:THEBR_RS03080
uniprot id: E8UW62
names: Similarity
messages: Belongs to the FGGY kinase family.

509193:THEBR RS02455
gene id: 509193:THEBR_RS02455
uniprot id: E8UVF0
names: Similarity
messages: Belongs to the UPF0047 family.

509193:THEBR RS05765
gene id: 509193:THEBR_RS05765
uniprot id: E8USR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

509193:THEBR RS00550
gene id: 509193:THEBR_RS00550
uniprot id: E8UTD4
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS10345
gene id: 509193:THEBR_RS10345
uniprot id: E8URA3
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

509193:THEBR RS09105
gene id: 509193:THEBR_RS09105
uniprot id: E8UWB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

509193:THEBR RS08030
gene id: 509193:THEBR_RS08030
uniprot id: E8UV55
names: Similarity
messages: Belongs to the YoeB family.

509193:THEBR RS05010
gene id: 509193:THEBR_RS05010
uniprot id: E8URY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS05055
gene id: 509193:THEBR_RS05055
uniprot id: E8URZ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS07990
gene id: 509193:THEBR_RS07990
uniprot id: E8UV46
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

509193:THEBR RS04160
gene id: 509193:THEBR_RS04160
uniprot id: E8UR24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

509193:THEBR RS09635
gene id: 509193:THEBR_RS09635
uniprot id: E8UWT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

509193:THEBR RS11055
gene id: 509193:THEBR_RS11055
uniprot id: E8US38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS00625
gene id: 509193:THEBR_RS00625
uniprot id: E8UTM6
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

509193:THEBR RS02680
gene id: 509193:THEBR_RS02680
uniprot id: E8UVQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

509193:THEBR RS01620
gene id: 509193:THEBR_RS01620
uniprot id: E8UUK7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

509193:THEBR RS02905
gene id: 509193:THEBR_RS02905
uniprot id: E8UW27
names: Similarity
messages: Belongs to the peptidase S41A family.

509193:THEBR RS07810
gene id: 509193:THEBR_RS07810
uniprot id: E8UUT9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

509193:THEBR RS05600
gene id: 509193:THEBR_RS05600
uniprot id: E8USN2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

509193:THEBR RS01965
gene id: 509193:THEBR_RS01965
uniprot id: E8UUZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

509193:THEBR RS08490
gene id: 509193:THEBR_RS08490
uniprot id: E8UVK2
names: Similarity
names: Subunit
messages: Belongs to the PdxA family. PdxA2 subfamily.
messages: Homodimer.

509193:THEBR RS11590
gene id: 509193:THEBR_RS11590
uniprot id: E8USL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

509193:THEBR RS08290
gene id: 509193:THEBR_RS08290
uniprot id: E8UVH0
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS04090
gene id: 509193:THEBR_RS04090
uniprot id: E8UR10
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

509193:THEBR RS01590
gene id: 509193:THEBR_RS01590
uniprot id: E8UUK1
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

509193:THEBR RS00115
gene id: 509193:THEBR_RS00115
uniprot id: E8USW8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

509193:THEBR RS10095
gene id: 509193:THEBR_RS10095
uniprot id: E8UQY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

509193:THEBR RS02700
gene id: 509193:THEBR_RS02700
uniprot id: E8UVR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS07080
gene id: 509193:THEBR_RS07080
uniprot id: E8UU83
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

509193:THEBR RS05075
gene id: 509193:THEBR_RS05075
uniprot id: E8US02
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

509193:THEBR RS10630
gene id: 509193:THEBR_RS10630
uniprot id: E8URN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS03100
gene id: 509193:THEBR_RS03100
uniprot id: E8UW66
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

509193:THEBR RS11130
gene id: 509193:THEBR_RS11130
uniprot id: E8US48
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

509193:THEBR RS02960
gene id: 509193:THEBR_RS02960
uniprot id: E8UW38
names: Cofactor
names: Similarity
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.

509193:THEBR RS02030
gene id: 509193:THEBR_RS02030
uniprot id: E8UV10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

509193:THEBR RS09610
gene id: 509193:THEBR_RS09610
uniprot id: E8UWT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

509193:THEBR RS04305
gene id: 509193:THEBR_RS04305
uniprot id: E8UR53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

509193:THEBR RS04495
gene id: 509193:THEBR_RS04495
uniprot id: E8URG2
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

509193:THEBR RS03760
gene id: 509193:THEBR_RS03760
uniprot id: E8UQM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

509193:THEBR RS10595
gene id: 509193:THEBR_RS10595
uniprot id: E8URM3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

509193:THEBR RS01955
gene id: 509193:THEBR_RS01955
uniprot id: E8UUZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

509193:THEBR RS11575
gene id: 509193:THEBR_RS11575
uniprot id: E8USL2
names: Similarity
messages: Belongs to the ParB family.

509193:THEBR RS01740
gene id: 509193:THEBR_RS01740
uniprot id: E8UUV2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

509193:THEBR RS07865
gene id: 509193:THEBR_RS07865
uniprot id: E8UV21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS08175
gene id: 509193:THEBR_RS08175
uniprot id: E8UV79
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

509193:THEBR RS09200
gene id: 509193:THEBR_RS09200
uniprot id: E8UWD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

509193:THEBR RS02895
gene id: 509193:THEBR_RS02895
uniprot id: E8UW25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

509193:THEBR RS05375
gene id: 509193:THEBR_RS05375
uniprot id: E8USD0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

509193:THEBR RS05965
gene id: 509193:THEBR_RS05965
uniprot id: E8USY8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

509193:THEBR RS07025
gene id: 509193:THEBR_RS07025
uniprot id: E8UTZ9
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS05865
gene id: 509193:THEBR_RS05865
uniprot id: E8UST6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

509193:THEBR RS00600
gene id: 509193:THEBR_RS00600
uniprot id: E8UTM1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

509193:THEBR RS07705
gene id: 509193:THEBR_RS07705
uniprot id: E8UUR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS10105
gene id: 509193:THEBR_RS10105
uniprot id: E8UQY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

509193:THEBR RS08565
gene id: 509193:THEBR_RS08565
uniprot id: E8UVL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

509193:THEBR RS10985
gene id: 509193:THEBR_RS10985
uniprot id: E8US24
names: Similarity
messages: Belongs to the class-I fumarase family.

509193:THEBR RS04860
gene id: 509193:THEBR_RS04860
uniprot id: E8URV8
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS10995
gene id: 509193:THEBR_RS10995
uniprot id: E8US26
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

509193:THEBR RS04145
gene id: 509193:THEBR_RS04145
uniprot id: E8UR21
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS10515
gene id: 509193:THEBR_RS10515
uniprot id: E8URD2
names: Similarity
messages: Belongs to the UxaA family.

509193:THEBR RS11600
gene id: 509193:THEBR_RS11600
uniprot id: E8USL7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS04890
gene id: 509193:THEBR_RS04890
uniprot id: E8URW4
names: Similarity
messages: Belongs to the peptidase C56 family.

509193:THEBR RS08710
gene id: 509193:THEBR_RS08710
uniprot id: E8UVW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

509193:THEBR RS08205
gene id: 509193:THEBR_RS08205
uniprot id: E8UV85
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

509193:THEBR RS04655
gene id: 509193:THEBR_RS04655
uniprot id: E8URJ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

509193:THEBR RS09050
gene id: 509193:THEBR_RS09050
uniprot id: E8UWA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

509193:THEBR RS01855
gene id: 509193:THEBR_RS01855
uniprot id: E8UUX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

509193:THEBR RS01790
gene id: 509193:THEBR_RS01790
uniprot id: E8UUW2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

509193:THEBR RS08430
gene id: 509193:THEBR_RS08430
uniprot id: E8UVJ5
names: Similarity
messages: Belongs to the P(II) protein family.

509193:THEBR RS00840
gene id: 509193:THEBR_RS00840
uniprot id: E8UTR5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

509193:THEBR RS01880
gene id: 509193:THEBR_RS01880
uniprot id: E8UUY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

509193:THEBR RS03070
gene id: 509193:THEBR_RS03070
uniprot id: E8UW60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

509193:THEBR RS01675
gene id: 509193:THEBR_RS01675
uniprot id: E8UUL8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

509193:THEBR RS09265
gene id: 509193:THEBR_RS09265
uniprot id: E8UWE7
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

509193:THEBR RS06450
gene id: 509193:THEBR_RS06450
uniprot id: E8UTG4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

509193:THEBR RS06800
gene id: 509193:THEBR_RS06800
uniprot id: E8UTV5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS07355
gene id: 509193:THEBR_RS07355
uniprot id: E8UUD4
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

509193:THEBR RS05370
gene id: 509193:THEBR_RS05370
uniprot id: E8USC9
names: Similarity
messages: Belongs to the UPF0473 family.

509193:THEBR RS03635
gene id: 509193:THEBR_RS03635
uniprot id: E8UWP6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

509193:THEBR RS08610
gene id: 509193:THEBR_RS08610
uniprot id: E8UVL8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

509193:THEBR RS03220
gene id: 509193:THEBR_RS03220
uniprot id: E8UW89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

509193:THEBR RS08975
gene id: 509193:THEBR_RS08975
uniprot id: E8UW17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS02870
gene id: 509193:THEBR_RS02870
uniprot id: E8UVU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

509193:THEBR RS01050
gene id: 509193:THEBR_RS01050
uniprot id: E8UU28
names: Similarity
messages: Belongs to the peptidase C40 family.

509193:THEBR RS06630
gene id: 509193:THEBR_RS06630
uniprot id: E8UTK0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

509193:THEBR RS01090
gene id: 509193:THEBR_RS01090
uniprot id: E8UU37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

509193:THEBR RS01545
gene id: 509193:THEBR_RS01545
uniprot id: E8UUJ1
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

509193:THEBR RS07715
gene id: 509193:THEBR_RS07715
uniprot id: E8UUS1
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

509193:THEBR RS03745
gene id: 509193:THEBR_RS03745
uniprot id: E8UQM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

509193:THEBR RS07140
gene id: 509193:THEBR_RS07140
uniprot id: E8UU95
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS10955
gene id: 509193:THEBR_RS10955
uniprot id: E8URU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

509193:THEBR RS00675
gene id: 509193:THEBR_RS00675
uniprot id: E8UTN5
names: Similarity
messages: Belongs to the peptidase S51 family.

509193:THEBR RS06160
gene id: 509193:THEBR_RS06160
uniprot id: E8UT27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

509193:THEBR RS08370
gene id: 509193:THEBR_RS08370
uniprot id: E8UVI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

509193:THEBR RS07560
gene id: 509193:THEBR_RS07560
uniprot id: E8UUP4
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

509193:THEBR RS01060
gene id: 509193:THEBR_RS01060
uniprot id: E8UU30
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

509193:THEBR RS00515
gene id: 509193:THEBR_RS00515
uniprot id: E8UTC7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

509193:THEBR RS04625
gene id: 509193:THEBR_RS04625
uniprot id: E8URI7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

509193:THEBR RS07735
gene id: 509193:THEBR_RS07735
uniprot id: E8UUS5
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

509193:THEBR RS10875
gene id: 509193:THEBR_RS10875
uniprot id: E8URT1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

509193:THEBR RS11060
gene id: 509193:THEBR_RS11060
uniprot id: E8US39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS00555
gene id: 509193:THEBR_RS00555
uniprot id: E8UTL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

509193:THEBR RS00855
gene id: 509193:THEBR_RS00855
uniprot id: E8UTR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

509193:THEBR RS03925
gene id: 509193:THEBR_RS03925
uniprot id: E8UQQ2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS04250
gene id: 509193:THEBR_RS04250
uniprot id: E8UR42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

509193:THEBR RS10665
gene id: 509193:THEBR_RS10665
uniprot id: E8URN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

509193:THEBR RS04475
gene id: 509193:THEBR_RS04475
uniprot id: E8URF8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS05415
gene id: 509193:THEBR_RS05415
uniprot id: E8USD8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

509193:THEBR RS05190
gene id: 509193:THEBR_RS05190
uniprot id: E8US91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

509193:THEBR RS04105
gene id: 509193:THEBR_RS04105
uniprot id: E8UR13
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

509193:THEBR RS02755
gene id: 509193:THEBR_RS02755
uniprot id: E8UVS3
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

509193:THEBR RS11530
gene id: 509193:THEBR_RS11530
uniprot id: E8USK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

509193:THEBR RS05435
gene id: 509193:THEBR_RS05435
uniprot id: E8USE2
names: Similarity
messages: Belongs to the GSP E family.

509193:THEBR RS05120
gene id: 509193:THEBR_RS05120
uniprot id: E8US09
names: Similarity
messages: Belongs to the IMPACT family.

509193:THEBR RS01945
gene id: 509193:THEBR_RS01945
uniprot id: E8UUZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

509193:THEBR RS10170
gene id: 509193:THEBR_RS10170
uniprot id: E8UQZ7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

509193:THEBR RS03865
gene id: 509193:THEBR_RS03865
uniprot id: E8UQP5
names: Subcellular Location Annotation
messages: Cytoplasm

509193:THEBR RS01970
gene id: 509193:THEBR_RS01970
uniprot id: E8UUZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

509193:THEBR RS05590
gene id: 509193:THEBR_RS05590
uniprot id: E8USN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

509193:THEBR RS01640
gene id: 509193:THEBR_RS01640
uniprot id: E8UUL1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

509193:THEBR RS10700
gene id: 509193:THEBR_RS10700
uniprot id: E8URP5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS02675
gene id: 509193:THEBR_RS02675
uniprot id: E8UVQ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

509193:THEBR RS08350
gene id: 509193:THEBR_RS08350
uniprot id: E8UVI0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

509193:THEBR RS06910
gene id: 509193:THEBR_RS06910
uniprot id: E8UTX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

509193:THEBR RS01360
gene id: 509193:THEBR_RS01360
uniprot id: E8UUF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 66 family.

509193:THEBR RS00835
gene id: 509193:THEBR_RS00835
uniprot id: E8UTR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

509193:THEBR RS01225
gene id: 509193:THEBR_RS01225
uniprot id: E8UU61
names: Function
messages: Involved in the transposition of the insertion sequence.

509193:THEBR RS10895
gene id: 509193:THEBR_RS10895
uniprot id: E8URT5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

509193:THEBR RS08075
gene id: 509193:THEBR_RS08075
uniprot id: E8UV63
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

509193:THEBR RS00010
gene id: 509193:THEBR_RS00010
uniprot id: E8USU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

509193:THEBR RS06625
gene id: 509193:THEBR_RS06625
uniprot id: E8UTJ9
names: Similarity
messages: Belongs to the asp23 family.

509193:THEBR RS11435
gene id: 509193:THEBR_RS11435
uniprot id: E8USI4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

509193:THEBR RS02015
gene id: 509193:THEBR_RS02015
uniprot id: E8UV07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

509193:THEBR RS02570
gene id: 509193:THEBR_RS02570
uniprot id: E8UVN5
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

509193:THEBR RS08860
gene id: 509193:THEBR_RS08860
uniprot id: E8UVZ4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

509193:THEBR RS06665
gene id: 509193:THEBR_RS06665
uniprot id: E8UTK7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

509193:THEBR RS10430
gene id: 509193:THEBR_RS10430
uniprot id: E8URB4
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

509193:THEBR RS04525
gene id: 509193:THEBR_RS04525
uniprot id: E8URG8
names: Similarity
messages: Belongs to the UPF0045 family.

509193:THEBR RS10005
gene id: 509193:THEBR_RS10005
uniprot id: E8UQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

509193:THEBR RS03535
gene id: 509193:THEBR_RS03535
uniprot id: E8UWM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS07130
gene id: 509193:THEBR_RS07130
uniprot id: E8UU93
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

509193:THEBR RS08560
gene id: 509193:THEBR_RS08560
uniprot id: E8UVK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

509193:THEBR RS10085
gene id: 509193:THEBR_RS10085
uniprot id: E8UQY0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

509193:THEBR RS08385
gene id: 509193:THEBR_RS08385
uniprot id: E8UVI6
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

509193:THEBR RS06055
gene id: 509193:THEBR_RS06055
uniprot id: E8UT06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

509193:THEBR RS03785
gene id: 509193:THEBR_RS03785
uniprot id: E8UQN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

509193:THEBR RS10745
gene id: 509193:THEBR_RS10745
uniprot id: E8URQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

509193:THEBR RS10025
gene id: 509193:THEBR_RS10025
uniprot id: E8UQW9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

509193:THEBR RS01525
gene id: 509193:THEBR_RS01525
uniprot id: E8UUI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

509193:THEBR RS00845
gene id: 509193:THEBR_RS00845
uniprot id: E8UTR6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

509193:THEBR RS06270
gene id: 509193:THEBR_RS06270
uniprot id: E8UT49
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

509193:THEBR RS04830
gene id: 509193:THEBR_RS04830
uniprot id: E8URV2
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

509193:THEBR RS11195
gene id: 509193:THEBR_RS11195
uniprot id: E8US57
names: Similarity
messages: Belongs to the peptidase A24 family.

509193:THEBR RS09060
gene id: 509193:THEBR_RS09060
uniprot id: E8UWB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

509193:THEBR RS04980
gene id: 509193:THEBR_RS04980
uniprot id: E8URY2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS11465
gene id: 509193:THEBR_RS11465
uniprot id: E8USJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

509193:THEBR RS07595
gene id: 509193:THEBR_RS07595
uniprot id: E8UUQ0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

509193:THEBR RS09800
gene id: 509193:THEBR_RS09800
uniprot id: E8UQS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Homodimer.
messages: Monomer.
messages: Secreted

509193:THEBR RS08235
gene id: 509193:THEBR_RS08235
uniprot id: E8UV90
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS05870
gene id: 509193:THEBR_RS05870
uniprot id: E8UST7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS04820
gene id: 509193:THEBR_RS04820
uniprot id: E8URU9
names: Subcellular Location Annotation
messages: Cell membrane

509193:THEBR RS06490
gene id: 509193:THEBR_RS06490
uniprot id: E8UTH2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

509193:THEBR RS08720
gene id: 509193:THEBR_RS08720
uniprot id: E8UVW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

509193:THEBR RS03710
gene id: 509193:THEBR_RS03710
uniprot id: E8UQL9
names: Similarity
messages: Belongs to the sigma-54 factor family.

509193:THEBR RS02060
gene id: 509193:THEBR_RS02060
uniprot id: E8UV16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

509193:THEBR RS06925
gene id: 509193:THEBR_RS06925
uniprot id: E8UTX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

509193:THEBR RS11495
gene id: 509193:THEBR_RS11495
uniprot id: E8USJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

509193:THEBR RS11560
gene id: 509193:THEBR_RS11560
uniprot id: E8USK9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

509193:THEBR RS04895
gene id: 509193:THEBR_RS04895
uniprot id: E8URW5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

509193:THEBR RS10495
gene id: 509193:THEBR_RS10495
uniprot id: E8URC8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS02735
gene id: 509193:THEBR_RS02735
uniprot id: E8UVR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

509193:THEBR RS04260
gene id: 509193:THEBR_RS04260
uniprot id: E8UR44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

509193:THEBR RS07230
gene id: 509193:THEBR_RS07230
uniprot id: E8UUB0
names: Similarity
messages: Belongs to the asparagine synthetase family.

509193:THEBR RS03125
gene id: 509193:THEBR_RS03125
uniprot id: E8UW71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS01580
gene id: 509193:THEBR_RS01580
uniprot id: E8UUJ9
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

509193:THEBR RS02370
gene id: 509193:THEBR_RS02370
uniprot id: E8UVD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Probably a homodimer.

509193:THEBR RS09795
gene id: 509193:THEBR_RS09795
uniprot id: E8UQS3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

509193:THEBR RS09350
gene id: 509193:THEBR_RS09350
uniprot id: E8UWG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

509193:THEBR RS10065
gene id: 509193:THEBR_RS10065
uniprot id: E8UQX6
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS12555
gene id: 509193:THEBR_RS12555
uniprot id: E8URC5
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS07070
gene id: 509193:THEBR_RS07070
uniprot id: E8UU08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

509193:THEBR RS06840
gene id: 509193:THEBR_RS06840
uniprot id: E8UTW3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

509193:THEBR RS10455
gene id: 509193:THEBR_RS10455
uniprot id: E8URC0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

509193:THEBR RS01845
gene id: 509193:THEBR_RS01845
uniprot id: E8UUX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

509193:THEBR RS08495
gene id: 509193:THEBR_RS08495
uniprot id: E8UVK3
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

509193:THEBR RS07380
gene id: 509193:THEBR_RS07380
uniprot id: E8UUD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS03055
gene id: 509193:THEBR_RS03055
uniprot id: E8UW57
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

509193:THEBR RS11250
gene id: 509193:THEBR_RS11250
uniprot id: E8UT92
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS01950
gene id: 509193:THEBR_RS01950
uniprot id: E8UUZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

509193:THEBR RS06820
gene id: 509193:THEBR_RS06820
uniprot id: E8UTV9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS04165
gene id: 509193:THEBR_RS04165
uniprot id: E8UR25
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS06040
gene id: 509193:THEBR_RS06040
uniprot id: E8UT03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

509193:THEBR RS08930
gene id: 509193:THEBR_RS08930
uniprot id: E8UW08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

509193:THEBR RS10910
gene id: 509193:THEBR_RS10910
uniprot id: E8URT8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

509193:THEBR RS10415
gene id: 509193:THEBR_RS10415
uniprot id: E8URB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS00095
gene id: 509193:THEBR_RS00095
uniprot id: E8USW4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

509193:THEBR RS06520
gene id: 509193:THEBR_RS06520
uniprot id: E8UTH8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

509193:THEBR RS07620
gene id: 509193:THEBR_RS07620
uniprot id: E8UUQ5
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS01710
gene id: 509193:THEBR_RS01710
uniprot id: E8UUM4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

509193:THEBR RS01175
gene id: 509193:THEBR_RS01175
uniprot id: E8UU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

509193:THEBR RS00545
gene id: 509193:THEBR_RS00545
uniprot id: E8UTD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS00395
gene id: 509193:THEBR_RS00395
uniprot id: E8UTA3
names: Similarity
messages: Belongs to the peptidase A24 family.

509193:THEBR RS06710
gene id: 509193:THEBR_RS06710
uniprot id: E8UTU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

509193:THEBR RS11515
gene id: 509193:THEBR_RS11515
uniprot id: E8USK0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

509193:THEBR RS09920
gene id: 509193:THEBR_RS09920
uniprot id: E8UQU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

509193:THEBR RS07635
gene id: 509193:THEBR_RS07635
uniprot id: E8UUQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

509193:THEBR RS05895
gene id: 509193:THEBR_RS05895
uniprot id: E8USU2
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

509193:THEBR RS10315
gene id: 509193:THEBR_RS10315
uniprot id: E8UR98
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

509193:THEBR RS06420
gene id: 509193:THEBR_RS06420
uniprot id: E8UTF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

509193:THEBR RS01235
gene id: 509193:THEBR_RS01235
uniprot id: E8UU63
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

509193:THEBR RS08730
gene id: 509193:THEBR_RS08730
uniprot id: E8UVW7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

509193:THEBR RS01800
gene id: 509193:THEBR_RS01800
uniprot id: E8UUW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

509193:THEBR RS04040
gene id: 509193:THEBR_RS04040
uniprot id: E8UR00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

509193:THEBR RS04230
gene id: 509193:THEBR_RS04230
uniprot id: E8UR38
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

509193:THEBR RS02965
gene id: 509193:THEBR_RS02965
uniprot id: E8UW39
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

509193:THEBR RS04665
gene id: 509193:THEBR_RS04665
uniprot id: E8URJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS05580
gene id: 509193:THEBR_RS05580
uniprot id: E8USM8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

509193:THEBR RS10055
gene id: 509193:THEBR_RS10055
uniprot id: E8UQX4
names: Similarity
messages: Belongs to the UPF0309 family.

509193:THEBR RS02690
gene id: 509193:THEBR_RS02690
uniprot id: E8UVQ9
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

509193:THEBR RS05810
gene id: 509193:THEBR_RS05810
uniprot id: E8USS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

509193:THEBR RS02240
gene id: 509193:THEBR_RS02240
uniprot id: E8UVB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

509193:THEBR RS00605
gene id: 509193:THEBR_RS00605
uniprot id: E8UTM2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

509193:THEBR RS04175
gene id: 509193:THEBR_RS04175
uniprot id: E8UR27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS05615
gene id: 509193:THEBR_RS05615
uniprot id: E8USN5
names: Similarity
messages: Belongs to the TlyA family.

509193:THEBR RS03630
gene id: 509193:THEBR_RS03630
uniprot id: E8UWP5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

509193:THEBR RS10840
gene id: 509193:THEBR_RS10840
uniprot id: E8URS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

509193:THEBR RS06090
gene id: 509193:THEBR_RS06090
uniprot id: E8UT13
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

509193:THEBR RS06555
gene id: 509193:THEBR_RS06555
uniprot id: E8UTI5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

509193:THEBR RS07260
gene id: 509193:THEBR_RS07260
uniprot id: E8UUB6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

509193:THEBR RS00520
gene id: 509193:THEBR_RS00520
uniprot id: E8UTC8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

509193:THEBR RS03405
gene id: 509193:THEBR_RS03405
uniprot id: E8UWJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

509193:THEBR RS03725
gene id: 509193:THEBR_RS03725
uniprot id: E8UQM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

509193:THEBR RS03790
gene id: 509193:THEBR_RS03790
uniprot id: E8UQN3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

509193:THEBR RS04935
gene id: 509193:THEBR_RS04935
uniprot id: E8URX3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

509193:THEBR RS03045
gene id: 509193:THEBR_RS03045
uniprot id: E8UW55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS02665
gene id: 509193:THEBR_RS02665
uniprot id: E8UVQ4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

509193:THEBR RS00735
gene id: 509193:THEBR_RS00735
uniprot id: E8UTP7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

509193:THEBR RS03860
gene id: 509193:THEBR_RS03860
uniprot id: E8UQP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

509193:THEBR RS03960
gene id: 509193:THEBR_RS03960
uniprot id: E8UQQ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

509193:THEBR RS06110
gene id: 509193:THEBR_RS06110
uniprot id: E8UT17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

509193:THEBR RS08065
gene id: 509193:THEBR_RS08065
uniprot id: E8UV61
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

509193:THEBR RS05610
gene id: 509193:THEBR_RS05610
uniprot id: E8USN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

509193:THEBR RS07370
gene id: 509193:THEBR_RS07370
uniprot id: E8UUD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

509193:THEBR RS00925
gene id: 509193:THEBR_RS00925
uniprot id: E8UTT2
names: Similarity
messages: Belongs to the GerABKA family.

509193:THEBR RS09175
gene id: 509193:THEBR_RS09175
uniprot id: E8UWD1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS09660
gene id: 509193:THEBR_RS09660
uniprot id: E8UWU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

509193:THEBR RS00345
gene id: 509193:THEBR_RS00345
uniprot id: E8UT93
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS10015
gene id: 509193:THEBR_RS10015
uniprot id: E8UQW7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

509193:THEBR RS11135
gene id: 509193:THEBR_RS11135
uniprot id: E8US49
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

509193:THEBR RS07630
gene id: 509193:THEBR_RS07630
uniprot id: E8UUQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS05515
gene id: 509193:THEBR_RS05515
uniprot id: E8USF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

509193:THEBR RS04640
gene id: 509193:THEBR_RS04640
uniprot id: E8URJ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS05695
gene id: 509193:THEBR_RS05695
uniprot id: E8USQ2
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

509193:THEBR RS03155
gene id: 509193:THEBR_RS03155
uniprot id: E8UW77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS04135
gene id: 509193:THEBR_RS04135
uniprot id: E8UR19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

509193:THEBR RS08695
gene id: 509193:THEBR_RS08695
uniprot id: E8UVW0
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS06425
gene id: 509193:THEBR_RS06425
uniprot id: E8UTF9
names: Similarity
messages: Belongs to the UPF0102 family.

509193:THEBR RS10690
gene id: 509193:THEBR_RS10690
uniprot id: E8URP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

509193:THEBR RS05495
gene id: 509193:THEBR_RS05495
uniprot id: E8USF4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

509193:THEBR RS02720
gene id: 509193:THEBR_RS02720
uniprot id: E8UVR5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS05030
gene id: 509193:THEBR_RS05030
uniprot id: E8URZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

509193:THEBR RS09875
gene id: 509193:THEBR_RS09875
uniprot id: E8UQT9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

509193:THEBR RS06880
gene id: 509193:THEBR_RS06880
uniprot id: E8UTW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

509193:THEBR RS00690
gene id: 509193:THEBR_RS00690
uniprot id: E8UTN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

509193:THEBR RS00045
gene id: 509193:THEBR_RS00045
uniprot id: E8USV4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

509193:THEBR RS07925
gene id: 509193:THEBR_RS07925
uniprot id: E8UV33
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

509193:THEBR RS10190
gene id: 509193:THEBR_RS10190
uniprot id: E8UR75
names: Similarity
messages: Belongs to the threonine aldolase family.

509193:THEBR RS10590
gene id: 509193:THEBR_RS10590
uniprot id: E8URM2
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

509193:THEBR RS10925
gene id: 509193:THEBR_RS10925
uniprot id: E8URU1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

509193:THEBR RS10880
gene id: 509193:THEBR_RS10880
uniprot id: E8URT2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

509193:THEBR RS05425
gene id: 509193:THEBR_RS05425
uniprot id: E8USE0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS02750
gene id: 509193:THEBR_RS02750
uniprot id: E8UVS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

509193:THEBR RS09580
gene id: 509193:THEBR_RS09580
uniprot id: E8UWS7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

509193:THEBR RS01145
gene id: 509193:THEBR_RS01145
uniprot id: E8UU47
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

509193:THEBR RS04390
gene id: 509193:THEBR_RS04390
uniprot id: E8UR68
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

509193:THEBR RS06940
gene id: 509193:THEBR_RS06940
uniprot id: E8UTY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

509193:THEBR RS08555
gene id: 509193:THEBR_RS08555
uniprot id: E8UVK8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

509193:THEBR RS00995
gene id: 509193:THEBR_RS00995
uniprot id: E8UU18
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS06740
gene id: 509193:THEBR_RS06740
uniprot id: E8UTU6
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

509193:THEBR RS06935
gene id: 509193:THEBR_RS06935
uniprot id: E8UTY0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

509193:THEBR RS04125
gene id: 509193:THEBR_RS04125
uniprot id: E8UR17
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

509193:THEBR RS08815
gene id: 509193:THEBR_RS08815
uniprot id: E8UVY5
names: Similarity
messages: Belongs to the asp23 family.

509193:THEBR RS10075
gene id: 509193:THEBR_RS10075
uniprot id: E8UQX8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

509193:THEBR RS09220
gene id: 509193:THEBR_RS09220
uniprot id: E8UWD9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

509193:THEBR RS11040
gene id: 509193:THEBR_RS11040
uniprot id: E8US34
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

509193:THEBR RS02425
gene id: 509193:THEBR_RS02425
uniprot id: E8UVE5
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

509193:THEBR RS01575
gene id: 509193:THEBR_RS01575
uniprot id: E8UUJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

509193:THEBR RS01930
gene id: 509193:THEBR_RS01930
uniprot id: E8UUZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

509193:THEBR RS00030
gene id: 509193:THEBR_RS00030
uniprot id: E8USV1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

509193:THEBR RS00560
gene id: 509193:THEBR_RS00560
uniprot id: E8UTL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

509193:THEBR RS08300
gene id: 509193:THEBR_RS08300
uniprot id: E8UVH1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

509193:THEBR RS08885
gene id: 509193:THEBR_RS08885
uniprot id: E8UVZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

509193:THEBR RS02595
gene id: 509193:THEBR_RS02595
uniprot id: E8UVP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

509193:THEBR RS01615
gene id: 509193:THEBR_RS01615
uniprot id: E8UUK6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

509193:THEBR RS06355
gene id: 509193:THEBR_RS06355
uniprot id: E8UTE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS03740
gene id: 509193:THEBR_RS03740
uniprot id: E8UQM5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

509193:THEBR RS10205
gene id: 509193:THEBR_RS10205
uniprot id: E8UR78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

509193:THEBR RS06525
gene id: 509193:THEBR_RS06525
uniprot id: E8UTH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

509193:THEBR RS09850
gene id: 509193:THEBR_RS09850
uniprot id: E8UQT4
names: Similarity
messages: Belongs to the CapA family.

509193:THEBR RS01140
gene id: 509193:THEBR_RS01140
uniprot id: E8UU46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

509193:THEBR RS11585
gene id: 509193:THEBR_RS11585
uniprot id: E8USL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

509193:THEBR RS04185
gene id: 509193:THEBR_RS04185
uniprot id: E8UR29
names: Similarity
messages: Belongs to the UPF0749 family.

509193:THEBR RS08465
gene id: 509193:THEBR_RS08465
uniprot id: E8UVJ9
names: Similarity
messages: Belongs to the UPF0236 family.

509193:THEBR RS08985
gene id: 509193:THEBR_RS08985
uniprot id: E8URW7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

509193:THEBR RS01775
gene id: 509193:THEBR_RS01775
uniprot id: E8UUV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

509193:THEBR RS09215
gene id: 509193:THEBR_RS09215
uniprot id: E8UWD8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

509193:THEBR RS09210
gene id: 509193:THEBR_RS09210
uniprot id: E8UWD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

509193:THEBR RS08590
gene id: 509193:THEBR_RS08590
uniprot id: E8UVL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS10905
gene id: 509193:THEBR_RS10905
uniprot id: E8URT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

509193:THEBR RS02890
gene id: 509193:THEBR_RS02890
uniprot id: E8UW24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

509193:THEBR RS02505
gene id: 509193:THEBR_RS02505
uniprot id: E8UVG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

509193:THEBR RS10975
gene id: 509193:THEBR_RS10975
uniprot id: E8US22
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

509193:THEBR RS10775
gene id: 509193:THEBR_RS10775
uniprot id: E8URR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS05775
gene id: 509193:THEBR_RS05775
uniprot id: E8USR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

509193:THEBR RS09035
gene id: 509193:THEBR_RS09035
uniprot id: E8UWA5
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3'.
messages: Belongs to the DpnII type II restriction endonuclease family.

509193:THEBR RS03135
gene id: 509193:THEBR_RS03135
uniprot id: E8UW73
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

509193:THEBR RS06045
gene id: 509193:THEBR_RS06045
uniprot id: E8UT04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

509193:THEBR RS11700
gene id: 509193:THEBR_RS11700
uniprot id: E8UUW9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

509193:THEBR RS06340
gene id: 509193:THEBR_RS06340
uniprot id: E8UTE2
names: Similarity
messages: Belongs to the FlgD family.

509193:THEBR RS03540
gene id: 509193:THEBR_RS03540
uniprot id: E8UWM6
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

509193:THEBR RS00790
gene id: 509193:THEBR_RS00790
uniprot id: E8UTQ5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

509193:THEBR RS10815
gene id: 509193:THEBR_RS10815
uniprot id: E8URR9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

509193:THEBR RS05105
gene id: 509193:THEBR_RS05105
uniprot id: E8US06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

509193:THEBR RS04585
gene id: 509193:THEBR_RS04585
uniprot id: E8URI0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

509193:THEBR RS09025
gene id: 509193:THEBR_RS09025
uniprot id: E8UWA3
names: Similarity
messages: Belongs to the asparagine synthetase family.

509193:THEBR RS03685
gene id: 509193:THEBR_RS03685
uniprot id: E8UQL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

509193:THEBR RS01865
gene id: 509193:THEBR_RS01865
uniprot id: E8UUX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

509193:THEBR RS09485
gene id: 509193:THEBR_RS09485
uniprot id: E8UWR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS06030
gene id: 509193:THEBR_RS06030
uniprot id: E8UT01
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

509193:THEBR RS07700
gene id: 509193:THEBR_RS07700
uniprot id: E8UUR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS09740
gene id: 509193:THEBR_RS09740
uniprot id: E8UWV5
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

509193:THEBR RS00955
gene id: 509193:THEBR_RS00955
uniprot id: E8UU10
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

509193:THEBR RS00970
gene id: 509193:THEBR_RS00970
uniprot id: E8UU13
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

509193:THEBR RS01105
gene id: 509193:THEBR_RS01105
uniprot id: E8UU40
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

509193:THEBR RS06380
gene id: 509193:THEBR_RS06380
uniprot id: E8UTF0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

509193:THEBR RS04405
gene id: 509193:THEBR_RS04405
uniprot id: E8UR71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

509193:THEBR RS08725
gene id: 509193:THEBR_RS08725
uniprot id: E8UVW6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

509193:THEBR RS11170
gene id: 509193:THEBR_RS11170
uniprot id: E8US54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

509193:THEBR RS05130
gene id: 509193:THEBR_RS05130
uniprot id: E8US11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS03815
gene id: 509193:THEBR_RS03815
uniprot id: E8UQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS08585
gene id: 509193:THEBR_RS08585
uniprot id: E8UVL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS06670
gene id: 509193:THEBR_RS06670
uniprot id: E8UTK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

509193:THEBR RS04400
gene id: 509193:THEBR_RS04400
uniprot id: E8UR70
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

509193:THEBR RS06540
gene id: 509193:THEBR_RS06540
uniprot id: E8UTI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

509193:THEBR RS10420
gene id: 509193:THEBR_RS10420
uniprot id: E8URB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS00870
gene id: 509193:THEBR_RS00870
uniprot id: E8UTS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

509193:THEBR RS11615
gene id: 509193:THEBR_RS11615
uniprot id: E8USM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

509193:THEBR RS01910
gene id: 509193:THEBR_RS01910
uniprot id: E8UUY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

509193:THEBR RS10435
gene id: 509193:THEBR_RS10435
uniprot id: E8URB5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

509193:THEBR RS06210
gene id: 509193:THEBR_RS06210
uniprot id: E8UT37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

509193:THEBR RS05690
gene id: 509193:THEBR_RS05690
uniprot id: E8USQ1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

509193:THEBR RS05260
gene id: 509193:THEBR_RS05260
uniprot id: E8USA6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

509193:THEBR RS00335
gene id: 509193:THEBR_RS00335
uniprot id: E8US69
names: Similarity
messages: Belongs to the GSP E family.

509193:THEBR RS06975
gene id: 509193:THEBR_RS06975
uniprot id: E8UTY8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

509193:THEBR RS04635
gene id: 509193:THEBR_RS04635
uniprot id: E8URI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

509193:THEBR RS00800
gene id: 509193:THEBR_RS00800
uniprot id: E8UTQ7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

509193:THEBR RS03210
gene id: 509193:THEBR_RS03210
uniprot id: E8UW87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS04205
gene id: 509193:THEBR_RS04205
uniprot id: E8UR33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

509193:THEBR RS02025
gene id: 509193:THEBR_RS02025
uniprot id: E8UV09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

509193:THEBR RS11605
gene id: 509193:THEBR_RS11605
uniprot id: E8USL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

509193:THEBR RS06845
gene id: 509193:THEBR_RS06845
uniprot id: E8UTW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

509193:THEBR RS04975
gene id: 509193:THEBR_RS04975
uniprot id: E8URY1
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

509193:THEBR RS08415
gene id: 509193:THEBR_RS08415
uniprot id: E8UVJ2
names: Similarity
messages: Belongs to the glutamate synthase family.

509193:THEBR RS10340
gene id: 509193:THEBR_RS10340
uniprot id: E8URA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

509193:THEBR RS01630
gene id: 509193:THEBR_RS01630
uniprot id: E8UUK9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

509193:THEBR RS03780
gene id: 509193:THEBR_RS03780
uniprot id: E8UQN1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

509193:THEBR RS06275
gene id: 509193:THEBR_RS06275
uniprot id: E8UT50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

509193:THEBR RS08800
gene id: 509193:THEBR_RS08800
uniprot id: E8UVY2
names: Similarity
messages: Belongs to the glutamate synthase family.

509193:THEBR RS09790
gene id: 509193:THEBR_RS09790
uniprot id: E8UQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS09915
gene id: 509193:THEBR_RS09915
uniprot id: E8UQU7
names: Similarity
messages: Belongs to the Tlp family.

509193:THEBR RS01340
gene id: 509193:THEBR_RS01340
uniprot id: E8UU80
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

509193:THEBR RS10660
gene id: 509193:THEBR_RS10660
uniprot id: E8URN6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

509193:THEBR RS06375
gene id: 509193:THEBR_RS06375
uniprot id: E8UTE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

509193:THEBR RS07900
gene id: 509193:THEBR_RS07900
uniprot id: E8UV28
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

509193:THEBR RS06700
gene id: 509193:THEBR_RS06700
uniprot id: E8UTT8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS06725
gene id: 509193:THEBR_RS06725
uniprot id: E8UTU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS00685
gene id: 509193:THEBR_RS00685
uniprot id: E8UTN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

509193:THEBR RS08390
gene id: 509193:THEBR_RS08390
uniprot id: E8UVI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

509193:THEBR RS06415
gene id: 509193:THEBR_RS06415
uniprot id: E8UTF7
names: Similarity
messages: Belongs to the DprA/Smf family.

509193:THEBR RS06440
gene id: 509193:THEBR_RS06440
uniprot id: E8UTG2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

509193:THEBR RS00565
gene id: 509193:THEBR_RS00565
uniprot id: E8UTL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

509193:THEBR RS10245
gene id: 509193:THEBR_RS10245
uniprot id: E8UR85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

509193:THEBR RS02485
gene id: 509193:THEBR_RS02485
uniprot id: E8UVF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

509193:THEBR RS00020
gene id: 509193:THEBR_RS00020
uniprot id: E8USU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

509193:THEBR RS08435
gene id: 509193:THEBR_RS08435
uniprot id: E8UVJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS04150
gene id: 509193:THEBR_RS04150
uniprot id: E8UR22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

509193:THEBR RS04200
gene id: 509193:THEBR_RS04200
uniprot id: E8UR32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

509193:THEBR RS06600
gene id: 509193:THEBR_RS06600
uniprot id: E8UTJ4
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

509193:THEBR RS06445
gene id: 509193:THEBR_RS06445
uniprot id: E8UTG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

509193:THEBR RS08675
gene id: 509193:THEBR_RS08675
uniprot id: E8UVV6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

509193:THEBR RS10390
gene id: 509193:THEBR_RS10390
uniprot id: E8URA7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

509193:THEBR RS00495
gene id: 509193:THEBR_RS00495
uniprot id: E8UTC3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

509193:THEBR RS02020
gene id: 509193:THEBR_RS02020
uniprot id: E8UV08
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

509193:THEBR RS09895
gene id: 509193:THEBR_RS09895
uniprot id: E8UQU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YdjC deacetylase family.
messages: Homodimer.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

509193:THEBR RS02385
gene id: 509193:THEBR_RS02385
uniprot id: E8UVD7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

509193:THEBR RS05745
gene id: 509193:THEBR_RS05745
uniprot id: E8USR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

509193:THEBR RS09330
gene id: 509193:THEBR_RS09330
uniprot id: E8UWG0
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS05440
gene id: 509193:THEBR_RS05440
uniprot id: E8USE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS01645
gene id: 509193:THEBR_RS01645
uniprot id: E8UUL2
names: Similarity
messages: Belongs to the SfsA family.

509193:THEBR RS09185
gene id: 509193:THEBR_RS09185
uniprot id: E8UWD3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS06295
gene id: 509193:THEBR_RS06295
uniprot id: E8UT54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

509193:THEBR RS07490
gene id: 509193:THEBR_RS07490
uniprot id: E8UUN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

509193:THEBR RS03130
gene id: 509193:THEBR_RS03130
uniprot id: E8UW72
names: Similarity
messages: Belongs to the glycosyl hydrolase.

509193:THEBR RS00905
gene id: 509193:THEBR_RS00905
uniprot id: E8UTS8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

509193:THEBR RS04960
gene id: 509193:THEBR_RS04960
uniprot id: E8URX8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

509193:THEBR RS03140
gene id: 509193:THEBR_RS03140
uniprot id: E8UW74
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

509193:THEBR RS05005
gene id: 509193:THEBR_RS05005
uniprot id: E8URY7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

509193:THEBR RS10465
gene id: 509193:THEBR_RS10465
uniprot id: E8URC2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

509193:THEBR RS10850
gene id: 509193:THEBR_RS10850
uniprot id: E8URS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

509193:THEBR RS10080
gene id: 509193:THEBR_RS10080
uniprot id: E8UQX9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

509193:THEBR RS08840
gene id: 509193:THEBR_RS08840
uniprot id: E8UVZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

509193:THEBR RS02560
gene id: 509193:THEBR_RS02560
uniprot id: E8UVN3
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS04740
gene id: 509193:THEBR_RS04740
uniprot id: E8URK9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

509193:THEBR RS03575
gene id: 509193:THEBR_RS03575
uniprot id: E8UWN4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

509193:THEBR RS06805
gene id: 509193:THEBR_RS06805
uniprot id: E8UTV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

509193:THEBR RS09585
gene id: 509193:THEBR_RS09585
uniprot id: E8UWS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

509193:THEBR RS02050
gene id: 509193:THEBR_RS02050
uniprot id: E8UV14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

509193:THEBR RS02390
gene id: 509193:THEBR_RS02390
uniprot id: E8UVD8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

509193:THEBR RS03380
gene id: 509193:THEBR_RS03380
uniprot id: E8UWJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

509193:THEBR RS02825
gene id: 509193:THEBR_RS02825
uniprot id: E8UVT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

509193:THEBR RS05585
gene id: 509193:THEBR_RS05585
uniprot id: E8USM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

509193:THEBR RS08320
gene id: 509193:THEBR_RS08320
uniprot id: E8UVH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

509193:THEBR RS06900
gene id: 509193:THEBR_RS06900
uniprot id: E8UTX3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

509193:THEBR RS05355
gene id: 509193:THEBR_RS05355
uniprot id: E8USC6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

509193:THEBR RS11610
gene id: 509193:THEBR_RS11610
uniprot id: E8USL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

509193:THEBR RS10655
gene id: 509193:THEBR_RS10655
uniprot id: E8URN5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

509193:THEBR RS05685
gene id: 509193:THEBR_RS05685
uniprot id: E8USQ0
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

509193:THEBR RS09540
gene id: 509193:THEBR_RS09540
uniprot id: E8UWS1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

509193:THEBR RS06005
gene id: 509193:THEBR_RS06005
uniprot id: E8USZ6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

509193:THEBR RS04995
gene id: 509193:THEBR_RS04995
uniprot id: E8URY5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

509193:THEBR RS05955
gene id: 509193:THEBR_RS05955
uniprot id: E8USY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

509193:THEBR RS00110
gene id: 509193:THEBR_RS00110
uniprot id: E8USW7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

509193:THEBR RS05270
gene id: 509193:THEBR_RS05270
uniprot id: E8USA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

509193:THEBR RS01660
gene id: 509193:THEBR_RS01660
uniprot id: E8UUL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

509193:THEBR RS11475
gene id: 509193:THEBR_RS11475
uniprot id: E8USJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

509193:THEBR RS03480
gene id: 509193:THEBR_RS03480
uniprot id: E8UWL4
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

509193:THEBR RS11490
gene id: 509193:THEBR_RS11490
uniprot id: E8USJ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

509193:THEBR RS00930
gene id: 509193:THEBR_RS00930
uniprot id: E8UTT3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

509193:THEBR RS08685
gene id: 509193:THEBR_RS08685
uniprot id: E8UVV8
names: Similarity
messages: Belongs to the GARS family.

509193:THEBR RS05660
gene id: 509193:THEBR_RS05660
uniprot id: E8USP4
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS04500
gene id: 509193:THEBR_RS04500
uniprot id: E8URG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

509193:THEBR RS05430
gene id: 509193:THEBR_RS05430
uniprot id: E8USE1
names: Similarity
messages: Belongs to the GSP E family.

509193:THEBR RS09690
gene id: 509193:THEBR_RS09690
uniprot id: E8UWU6
names: Similarity
messages: Belongs to the PemK/MazF family.

509193:THEBR RS06455
gene id: 509193:THEBR_RS06455
uniprot id: E8UTG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

509193:THEBR RS03695
gene id: 509193:THEBR_RS03695
uniprot id: E8UQL6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

509193:THEBR RS07725
gene id: 509193:THEBR_RS07725
uniprot id: E8UUS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS08250
gene id: 509193:THEBR_RS08250
uniprot id: E8UVG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

509193:THEBR RS08505
gene id: 509193:THEBR_RS08505
uniprot id: E8UVK5
names: Similarity
messages: Belongs to the UxaA family.

509193:THEBR RS04095
gene id: 509193:THEBR_RS04095
uniprot id: E8UR11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

509193:THEBR RS06565
gene id: 509193:THEBR_RS06565
uniprot id: E8UTI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

509193:THEBR RS09365
gene id: 509193:THEBR_RS09365
uniprot id: E8UWG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

509193:THEBR RS07265
gene id: 509193:THEBR_RS07265
uniprot id: E8UUB7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

509193:THEBR RS09055
gene id: 509193:THEBR_RS09055
uniprot id: E8UWA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

509193:THEBR RS03095
gene id: 509193:THEBR_RS03095
uniprot id: E8UW65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

509193:THEBR RS10675
gene id: 509193:THEBR_RS10675
uniprot id: E8URP0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

509193:THEBR RS08845
gene id: 509193:THEBR_RS08845
uniprot id: E8UVZ2
names: Similarity
messages: Belongs to the MotB family.

509193:THEBR RS05345
gene id: 509193:THEBR_RS05345
uniprot id: E8USC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS01990
gene id: 509193:THEBR_RS01990
uniprot id: E8UV02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

509193:THEBR RS06285
gene id: 509193:THEBR_RS06285
uniprot id: E8UT52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

509193:THEBR RS07750
gene id: 509193:THEBR_RS07750
uniprot id: E8UUS8
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

509193:THEBR RS10915
gene id: 509193:THEBR_RS10915
uniprot id: E8URT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

509193:THEBR RS02220
gene id: 509193:THEBR_RS02220
uniprot id: E8UVA8
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

509193:THEBR RS09040
gene id: 509193:THEBR_RS09040
uniprot id: E8UWA6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

509193:THEBR RS06185
gene id: 509193:THEBR_RS06185
uniprot id: E8UT32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

509193:THEBR RS06190
gene id: 509193:THEBR_RS06190
uniprot id: E8UT33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS06510
gene id: 509193:THEBR_RS06510
uniprot id: E8UTH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

509193:THEBR RS04530
gene id: 509193:THEBR_RS04530
uniprot id: E8URG9
names: Similarity
messages: Belongs to the CapA family.

509193:THEBR RS07225
gene id: 509193:THEBR_RS07225
uniprot id: E8UUA9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

509193:THEBR RS04195
gene id: 509193:THEBR_RS04195
uniprot id: E8UR31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

509193:THEBR RS06205
gene id: 509193:THEBR_RS06205
uniprot id: E8UT36
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS08900
gene id: 509193:THEBR_RS08900
uniprot id: E8UW02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

509193:THEBR RS07360
gene id: 509193:THEBR_RS07360
uniprot id: E8UUD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

509193:THEBR RS09855
gene id: 509193:THEBR_RS09855
uniprot id: E8UQT5
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

509193:THEBR RS10625
gene id: 509193:THEBR_RS10625
uniprot id: E8URM9
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

509193:THEBR RS09360
gene id: 509193:THEBR_RS09360
uniprot id: E8UWG6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS00945
gene id: 509193:THEBR_RS00945
uniprot id: E8UTT6
names: Similarity
messages: Belongs to the SleB family.

509193:THEBR RS02935
gene id: 509193:THEBR_RS02935
uniprot id: E8UW33
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS08640
gene id: 509193:THEBR_RS08640
uniprot id: E8UVU9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

509193:THEBR RS01400
gene id: 509193:THEBR_RS01400
uniprot id: E8UUG4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

509193:THEBR RS08870
gene id: 509193:THEBR_RS08870
uniprot id: E8UVZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

509193:THEBR RS11245
gene id: 509193:THEBR_RS11245
uniprot id: E8US67
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS09665
gene id: 509193:THEBR_RS09665
uniprot id: E8UWU1
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS05170
gene id: 509193:THEBR_RS05170
uniprot id: E8US87
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

509193:THEBR RS03550
gene id: 509193:THEBR_RS03550
uniprot id: E8UWM8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

509193:THEBR RS01350
gene id: 509193:THEBR_RS01350
uniprot id: E8UUF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS09600
gene id: 509193:THEBR_RS09600
uniprot id: E8UWT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

509193:THEBR RS09755
gene id: 509193:THEBR_RS09755
uniprot id: E8UWV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

509193:THEBR RS02865
gene id: 509193:THEBR_RS02865
uniprot id: E8UVU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

509193:THEBR RS07345
gene id: 509193:THEBR_RS07345
uniprot id: E8UUD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

509193:THEBR RS06825
gene id: 509193:THEBR_RS06825
uniprot id: E8UTW0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

509193:THEBR RS07600
gene id: 509193:THEBR_RS07600
uniprot id: E8UUQ1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

509193:THEBR RS10270
gene id: 509193:THEBR_RS10270
uniprot id: E8UR90
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS01220
gene id: 509193:THEBR_RS01220
uniprot id: E8UU59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

509193:THEBR RS10580
gene id: 509193:THEBR_RS10580
uniprot id: E8URE5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

509193:THEBR RS07340
gene id: 509193:THEBR_RS07340
uniprot id: E8UUD1
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS01925
gene id: 509193:THEBR_RS01925
uniprot id: E8UUY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

509193:THEBR RS11145
gene id: 509193:THEBR_RS11145
uniprot id: E8US51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

509193:THEBR RS08345
gene id: 509193:THEBR_RS08345
uniprot id: E8UVH9
names: Similarity
messages: Belongs to the EamA transporter family.

509193:THEBR RS02035
gene id: 509193:THEBR_RS02035
uniprot id: E8UV11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

509193:THEBR RS03755
gene id: 509193:THEBR_RS03755
uniprot id: E8UQM8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

509193:THEBR RS11450
gene id: 509193:THEBR_RS11450
uniprot id: E8USI7
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

509193:THEBR RS04190
gene id: 509193:THEBR_RS04190
uniprot id: E8UR30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

509193:THEBR RS04670
gene id: 509193:THEBR_RS04670
uniprot id: E8URJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

509193:THEBR RS04520
gene id: 509193:THEBR_RS04520
uniprot id: E8URG7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

509193:THEBR RS01585
gene id: 509193:THEBR_RS01585
uniprot id: E8UUK0
names: Similarity
messages: Belongs to the GerABKA family.

509193:THEBR RS06590
gene id: 509193:THEBR_RS06590
uniprot id: E8UTJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

509193:THEBR RS01465
gene id: 509193:THEBR_RS01465
uniprot id: E8UUH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

509193:THEBR RS03665
gene id: 509193:THEBR_RS03665
uniprot id: E8UQL0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

509193:THEBR RS10650
gene id: 509193:THEBR_RS10650
uniprot id: E8URN4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

509193:THEBR RS08760
gene id: 509193:THEBR_RS08760
uniprot id: E8UVX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

509193:THEBR RS06530
gene id: 509193:THEBR_RS06530
uniprot id: E8UTI0
names: Similarity
messages: Belongs to the fabD family.

509193:THEBR RS06760
gene id: 509193:THEBR_RS06760
uniprot id: E8UTV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

509193:THEBR RS02605
gene id: 509193:THEBR_RS02605
uniprot id: E8UVP2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS01975
gene id: 509193:THEBR_RS01975
uniprot id: E8UUZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

509193:THEBR RS06000
gene id: 509193:THEBR_RS06000
uniprot id: E8USZ5
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

509193:THEBR RS07100
gene id: 509193:THEBR_RS07100
uniprot id: E8UU87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

509193:THEBR RS07640
gene id: 509193:THEBR_RS07640
uniprot id: E8UUQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

509193:THEBR RS05980
gene id: 509193:THEBR_RS05980
uniprot id: E8USZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

509193:THEBR RS04030
gene id: 509193:THEBR_RS04030
uniprot id: E8UQZ8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

509193:THEBR RS07895
gene id: 509193:THEBR_RS07895
uniprot id: E8UV27
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

509193:THEBR RS02955
gene id: 509193:THEBR_RS02955
uniprot id: E8UW37
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

509193:THEBR RS02915
gene id: 509193:THEBR_RS02915
uniprot id: E8UW29
names: Similarity
messages: Belongs to the ComB family.

509193:THEBR RS07210
gene id: 509193:THEBR_RS07210
uniprot id: E8UUA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

509193:THEBR RS01755
gene id: 509193:THEBR_RS01755
uniprot id: E8UUV5
names: Similarity
messages: Belongs to the ycf81 family.

509193:THEBR RS00130
gene id: 509193:THEBR_RS00130
uniprot id: E8USX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS06385
gene id: 509193:THEBR_RS06385
uniprot id: E8UTF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

509193:THEBR RS01960
gene id: 509193:THEBR_RS01960
uniprot id: E8UUZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

509193:THEBR RS02245
gene id: 509193:THEBR_RS02245
uniprot id: E8UVB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS02790
gene id: 509193:THEBR_RS02790
uniprot id: E8UVT0
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

509193:THEBR RS09165
gene id: 509193:THEBR_RS09165
uniprot id: E8UWC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS05240
gene id: 509193:THEBR_RS05240
uniprot id: E8USA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

509193:THEBR RS06320
gene id: 509193:THEBR_RS06320
uniprot id: E8UTD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

509193:THEBR RS02465
gene id: 509193:THEBR_RS02465
uniprot id: E8UVF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

509193:THEBR RS10740
gene id: 509193:THEBR_RS10740
uniprot id: E8URQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

509193:THEBR RS04350
gene id: 509193:THEBR_RS04350
uniprot id: E8UR60
names: Similarity
messages: Belongs to the AOR/FOR family.

509193:THEBR RS02925
gene id: 509193:THEBR_RS02925
uniprot id: E8UW31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

509193:THEBR RS10225
gene id: 509193:THEBR_RS10225
uniprot id: E8UR81
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS09530
gene id: 509193:THEBR_RS09530
uniprot id: E8UWR9
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS08745
gene id: 509193:THEBR_RS08745
uniprot id: E8UVX0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

509193:THEBR RS10405
gene id: 509193:THEBR_RS10405
uniprot id: E8URA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

509193:THEBR RS02265
gene id: 509193:THEBR_RS02265
uniprot id: E8UVB5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS04215
gene id: 509193:THEBR_RS04215
uniprot id: E8UR35
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

509193:THEBR RS04460
gene id: 509193:THEBR_RS04460
uniprot id: E8URF5
names: Subcellular Location Annotation
messages: Cytoplasm

509193:THEBR RS00085
gene id: 509193:THEBR_RS00085
uniprot id: E8USW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

509193:THEBR RS01075
gene id: 509193:THEBR_RS01075
uniprot id: E8UU34
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS08690
gene id: 509193:THEBR_RS08690
uniprot id: E8UVV9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

509193:THEBR RS07590
gene id: 509193:THEBR_RS07590
uniprot id: E8UUP9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

509193:THEBR RS03675
gene id: 509193:THEBR_RS03675
uniprot id: E8UQL2
names: Similarity
messages: Belongs to the peptidase S16 family.

509193:THEBR RS04945
gene id: 509193:THEBR_RS04945
uniprot id: E8URX5
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

509193:THEBR RS07375
gene id: 509193:THEBR_RS07375
uniprot id: E8UUD8
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

509193:THEBR RS04430
gene id: 509193:THEBR_RS04430
uniprot id: E8URE9
names: Similarity
messages: Belongs to the RutC family.

509193:THEBR RS07095
gene id: 509193:THEBR_RS07095
uniprot id: E8UU86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

509193:THEBR RS05630
gene id: 509193:THEBR_RS05630
uniprot id: E8USN8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

509193:THEBR RS06080
gene id: 509193:THEBR_RS06080
uniprot id: E8UT11
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

509193:THEBR RS06810
gene id: 509193:THEBR_RS06810
uniprot id: E8UTV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

509193:THEBR RS07870
gene id: 509193:THEBR_RS07870
uniprot id: E8UV22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

509193:THEBR RS01760
gene id: 509193:THEBR_RS01760
uniprot id: E8UUV6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

509193:THEBR RS00100
gene id: 509193:THEBR_RS00100
uniprot id: E8USW5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

509193:THEBR RS07460
gene id: 509193:THEBR_RS07460
uniprot id: E8UUM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

509193:THEBR RS04470
gene id: 509193:THEBR_RS04470
uniprot id: E8URF7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

509193:THEBR RS09900
gene id: 509193:THEBR_RS09900
uniprot id: E8UQU4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

509193:THEBR RS03510
gene id: 509193:THEBR_RS03510
uniprot id: E8UWM0
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

509193:THEBR RS09735
gene id: 509193:THEBR_RS09735
uniprot id: E8UWV4
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

509193:THEBR RS09315
gene id: 509193:THEBR_RS09315
uniprot id: E8UWF7
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

509193:THEBR RS10705
gene id: 509193:THEBR_RS10705
uniprot id: E8URP6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

509193:THEBR RS11255
gene id: 509193:THEBR_RS11255
uniprot id: E8US69
names: Similarity
messages: Belongs to the GSP E family.

509193:THEBR RS05210
gene id: 509193:THEBR_RS05210
uniprot id: E8US96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

509193:THEBR RS01385
gene id: 509193:THEBR_RS01385
uniprot id: E8UUG1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

509193:THEBR RS06305
gene id: 509193:THEBR_RS06305
uniprot id: E8UT56
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

509193:THEBR RS10445
gene id: 509193:THEBR_RS10445
uniprot id: E8URB8
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS11440
gene id: 509193:THEBR_RS11440
uniprot id: E8USI5
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

509193:THEBR RS06435
gene id: 509193:THEBR_RS06435
uniprot id: E8UTG1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS10115
gene id: 509193:THEBR_RS10115
uniprot id: E8UQY6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS07390
gene id: 509193:THEBR_RS07390
uniprot id: E8UUE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

509193:THEBR RS06135
gene id: 509193:THEBR_RS06135
uniprot id: E8UT22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

509193:THEBR RS07500
gene id: 509193:THEBR_RS07500
uniprot id: E8UUN4
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS06390
gene id: 509193:THEBR_RS06390
uniprot id: E8UTF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

509193:THEBR RS07935
gene id: 509193:THEBR_RS07935
uniprot id: E8UV35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

509193:THEBR RS02075
gene id: 509193:THEBR_RS02075
uniprot id: E8UV19
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

509193:THEBR RS01935
gene id: 509193:THEBR_RS01935
uniprot id: E8UUZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

509193:THEBR RS10200
gene id: 509193:THEBR_RS10200
uniprot id: E8UR77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

509193:THEBR RS09645
gene id: 509193:THEBR_RS09645
uniprot id: E8UWT7
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

509193:THEBR RS12550
gene id: 509193:THEBR_RS12550
uniprot id: E8URC4
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS03750
gene id: 509193:THEBR_RS03750
uniprot id: E8UQM7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

509193:THEBR RS00740
gene id: 509193:THEBR_RS00740
uniprot id: E8UTP8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

509193:THEBR RS01625
gene id: 509193:THEBR_RS01625
uniprot id: E8UUK8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

509193:THEBR RS05970
gene id: 509193:THEBR_RS05970
uniprot id: E8USY9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

509193:THEBR RS05040
gene id: 509193:THEBR_RS05040
uniprot id: E8URZ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

509193:THEBR RS05250
gene id: 509193:THEBR_RS05250
uniprot id: E8USA4
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS10750
gene id: 509193:THEBR_RS10750
uniprot id: E8URQ6
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

509193:THEBR RS10670
gene id: 509193:THEBR_RS10670
uniprot id: E8URN8
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS06550
gene id: 509193:THEBR_RS06550
uniprot id: E8UTI4
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

509193:THEBR RS07065
gene id: 509193:THEBR_RS07065
uniprot id: E8UU07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

509193:THEBR RS08665
gene id: 509193:THEBR_RS08665
uniprot id: E8UVV4
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS05165
gene id: 509193:THEBR_RS05165
uniprot id: E8US18
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

509193:THEBR RS08265
gene id: 509193:THEBR_RS08265
uniprot id: E8UVG5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

509193:THEBR RS10500
gene id: 509193:THEBR_RS10500
uniprot id: E8URC9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

509193:THEBR RS11030
gene id: 509193:THEBR_RS11030
uniprot id: E8US32
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

509193:THEBR RS07615
gene id: 509193:THEBR_RS07615
uniprot id: E8UUQ4
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS06280
gene id: 509193:THEBR_RS06280
uniprot id: E8UT51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

509193:THEBR RS04380
gene id: 509193:THEBR_RS04380
uniprot id: E8UR66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS05070
gene id: 509193:THEBR_RS05070
uniprot id: E8US01
names: Similarity
messages: Belongs to the thioredoxin family.

509193:THEBR RS07840
gene id: 509193:THEBR_RS07840
uniprot id: E8UUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

509193:THEBR RS10450
gene id: 509193:THEBR_RS10450
uniprot id: E8URB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

509193:THEBR RS01785
gene id: 509193:THEBR_RS01785
uniprot id: E8UUW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

509193:THEBR RS07720
gene id: 509193:THEBR_RS07720
uniprot id: E8UUS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS03455
gene id: 509193:THEBR_RS03455
uniprot id: E8UWK9
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

509193:THEBR RS01665
gene id: 509193:THEBR_RS01665
uniprot id: E8UUL6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

509193:THEBR RS01825
gene id: 509193:THEBR_RS01825
uniprot id: E8UUW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

509193:THEBR RS01425
gene id: 509193:THEBR_RS01425
uniprot id: E8UUG9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

509193:THEBR RS09870
gene id: 509193:THEBR_RS09870
uniprot id: E8UQT8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

509193:THEBR RS07020
gene id: 509193:THEBR_RS07020
uniprot id: E8UTZ8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

509193:THEBR RS05640
gene id: 509193:THEBR_RS05640
uniprot id: E8USP0
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

509193:THEBR RS09885
gene id: 509193:THEBR_RS09885
uniprot id: E8UQU1
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

509193:THEBR RS07535
gene id: 509193:THEBR_RS07535
uniprot id: E8UUP0
names: Similarity
messages: Belongs to the HepT RNase toxin family.

509193:THEBR RS07480
gene id: 509193:THEBR_RS07480
uniprot id: E8UUN0
names: Similarity
messages: Belongs to the NadC/ModD family.

509193:THEBR RS06400
gene id: 509193:THEBR_RS06400
uniprot id: E8UTF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

509193:THEBR RS08615
gene id: 509193:THEBR_RS08615
uniprot id: E8UVL9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

509193:THEBR RS03450
gene id: 509193:THEBR_RS03450
uniprot id: E8UWK8
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

509193:THEBR RS00725
gene id: 509193:THEBR_RS00725
uniprot id: E8UTP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

509193:THEBR RS02945
gene id: 509193:THEBR_RS02945
uniprot id: E8UW35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

509193:THEBR RS11140
gene id: 509193:THEBR_RS11140
uniprot id: E8US50
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

509193:THEBR RS04170
gene id: 509193:THEBR_RS04170
uniprot id: E8UR26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS01915
gene id: 509193:THEBR_RS01915
uniprot id: E8UUY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

509193:THEBR RS06650
gene id: 509193:THEBR_RS06650
uniprot id: E8UTK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

509193:THEBR RS08715
gene id: 509193:THEBR_RS08715
uniprot id: E8UVW4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

509193:THEBR RS05625
gene id: 509193:THEBR_RS05625
uniprot id: E8USN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

509193:THEBR RS03205
gene id: 509193:THEBR_RS03205
uniprot id: E8UW86
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

509193:THEBR RS10110
gene id: 509193:THEBR_RS10110
uniprot id: E8UQY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

509193:THEBR RS05620
gene id: 509193:THEBR_RS05620
uniprot id: E8USN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS08625
gene id: 509193:THEBR_RS08625
uniprot id: E8UVM1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

509193:THEBR RS00730
gene id: 509193:THEBR_RS00730
uniprot id: E8UTP6
names: Similarity
messages: Belongs to the peptidase S8 family.

509193:THEBR RS09880
gene id: 509193:THEBR_RS09880
uniprot id: E8UQU0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

509193:THEBR RS01735
gene id: 509193:THEBR_RS01735
uniprot id: E8UUV1
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

509193:THEBR RS10900
gene id: 509193:THEBR_RS10900
uniprot id: E8URT6
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

509193:THEBR RS05135
gene id: 509193:THEBR_RS05135
uniprot id: E8US12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS01905
gene id: 509193:THEBR_RS01905
uniprot id: E8UUY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

509193:THEBR RS01430
gene id: 509193:THEBR_RS01430
uniprot id: E8UUH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

509193:THEBR RS10555
gene id: 509193:THEBR_RS10555
uniprot id: E8URD9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

509193:THEBR RS00645
gene id: 509193:THEBR_RS00645
uniprot id: E8UTN0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

509193:THEBR RS10525
gene id: 509193:THEBR_RS10525
uniprot id: E8URD4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

509193:THEBR RS09595
gene id: 509193:THEBR_RS09595
uniprot id: E8UWT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

509193:THEBR RS01000
gene id: 509193:THEBR_RS01000
uniprot id: E8UU19
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS03235
gene id: 509193:THEBR_RS03235
uniprot id: E8UW92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

509193:THEBR RS04330
gene id: 509193:THEBR_RS04330
uniprot id: E8UR57
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

509193:THEBR RS07385
gene id: 509193:THEBR_RS07385
uniprot id: E8UUE0
names: Similarity
messages: Belongs to the UPF0758 family.

509193:THEBR RS05945
gene id: 509193:THEBR_RS05945
uniprot id: E8USY4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

509193:THEBR RS01155
gene id: 509193:THEBR_RS01155
uniprot id: E8UU49
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

509193:THEBR RS05960
gene id: 509193:THEBR_RS05960
uniprot id: E8USY7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

509193:THEBR RS07940
gene id: 509193:THEBR_RS07940
uniprot id: E8UV36
names: Similarity
messages: Belongs to the HepT RNase toxin family.

509193:THEBR RS04540
gene id: 509193:THEBR_RS04540
uniprot id: E8URH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

509193:THEBR RS09820
gene id: 509193:THEBR_RS09820
uniprot id: E8UQS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS02250
gene id: 509193:THEBR_RS02250
uniprot id: E8UVB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS06885
gene id: 509193:THEBR_RS06885
uniprot id: E8UTX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

509193:THEBR RS10570
gene id: 509193:THEBR_RS10570
uniprot id: E8URE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

509193:THEBR RS03525
gene id: 509193:THEBR_RS03525
uniprot id: E8UWM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

509193:THEBR RS03315
gene id: 509193:THEBR_RS03315
uniprot id: E8UWI1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

509193:THEBR RS03105
gene id: 509193:THEBR_RS03105
uniprot id: E8UW67
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

509193:THEBR RS10185
gene id: 509193:THEBR_RS10185
uniprot id: E8UR74
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

509193:THEBR RS06290
gene id: 509193:THEBR_RS06290
uniprot id: E8UT53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

509193:THEBR RS06895
gene id: 509193:THEBR_RS06895
uniprot id: E8UTX2
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

509193:THEBR RS09305
gene id: 509193:THEBR_RS09305
uniprot id: E8UWF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

509193:THEBR RS00135
gene id: 509193:THEBR_RS00135
uniprot id: E8USX3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS07090
gene id: 509193:THEBR_RS07090
uniprot id: E8UU85
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

509193:THEBR RS00720
gene id: 509193:THEBR_RS00720
uniprot id: E8UTP4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

509193:THEBR RS02070
gene id: 509193:THEBR_RS02070
uniprot id: E8UV18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

509193:THEBR RS09590
gene id: 509193:THEBR_RS09590
uniprot id: E8UWS9
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS08365
gene id: 509193:THEBR_RS08365
uniprot id: E8UVI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

509193:THEBR RS02440
gene id: 509193:THEBR_RS02440
uniprot id: E8UVE7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

509193:THEBR RS07495
gene id: 509193:THEBR_RS07495
uniprot id: E8UUN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

509193:THEBR RS11445
gene id: 509193:THEBR_RS11445
uniprot id: E8USI6
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

509193:THEBR RS08965
gene id: 509193:THEBR_RS08965
uniprot id: E8UW15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

509193:THEBR RS06370
gene id: 509193:THEBR_RS06370
uniprot id: E8UTE8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

509193:THEBR RS06475
gene id: 509193:THEBR_RS06475
uniprot id: E8UTG9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

509193:THEBR RS03565
gene id: 509193:THEBR_RS03565
uniprot id: E8UWN1
names: Similarity
messages: Belongs to the manganese catalase family.

509193:THEBR RS10250
gene id: 509193:THEBR_RS10250
uniprot id: E8UR86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS05925
gene id: 509193:THEBR_RS05925
uniprot id: E8USY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

509193:THEBR RS04225
gene id: 509193:THEBR_RS04225
uniprot id: E8UR37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

509193:THEBR RS01985
gene id: 509193:THEBR_RS01985
uniprot id: E8UV01
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

509193:THEBR RS10280
gene id: 509193:THEBR_RS10280
uniprot id: E8UR92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

509193:THEBR RS06075
gene id: 509193:THEBR_RS06075
uniprot id: E8UT10
names: Similarity
messages: Belongs to the peptidase S14 family.

509193:THEBR RS06695
gene id: 509193:THEBR_RS06695
uniprot id: E8UTT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

509193:THEBR RS08830
gene id: 509193:THEBR_RS08830
uniprot id: E8UVY9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

509193:THEBR RS00780
gene id: 509193:THEBR_RS00780
uniprot id: E8UTQ3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

509193:THEBR RS10835
gene id: 509193:THEBR_RS10835
uniprot id: E8URS3
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS08335
gene id: 509193:THEBR_RS08335
uniprot id: E8UVH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS09415
gene id: 509193:THEBR_RS09415
uniprot id: E8UWP9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

509193:THEBR RS01890
gene id: 509193:THEBR_RS01890
uniprot id: E8UUY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

509193:THEBR RS03175
gene id: 509193:THEBR_RS03175
uniprot id: E8UW80
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS03475
gene id: 509193:THEBR_RS03475
uniprot id: E8UWL3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS06715
gene id: 509193:THEBR_RS06715
uniprot id: E8UTU1
names: Similarity
messages: Belongs to the RemA family.

509193:THEBR RS10920
gene id: 509193:THEBR_RS10920
uniprot id: E8URU0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

509193:THEBR RS07785
gene id: 509193:THEBR_RS07785
uniprot id: E8UUT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

509193:THEBR RS05200
gene id: 509193:THEBR_RS05200
uniprot id: E8US94
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

509193:THEBR RS10010
gene id: 509193:THEBR_RS10010
uniprot id: E8UQW6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

509193:THEBR RS06200
gene id: 509193:THEBR_RS06200
uniprot id: E8UT35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

509193:THEBR RS02535
gene id: 509193:THEBR_RS02535
uniprot id: E8UVM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS07250
gene id: 509193:THEBR_RS07250
uniprot id: E8UUB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

509193:THEBR RS10460
gene id: 509193:THEBR_RS10460
uniprot id: E8URC1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

509193:THEBR RS06720
gene id: 509193:THEBR_RS06720
uniprot id: E8UTU2
names: Similarity
messages: Belongs to the YicC/YloC family.

509193:THEBR RS08620
gene id: 509193:THEBR_RS08620
uniprot id: E8UVM0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

509193:THEBR RS09075
gene id: 509193:THEBR_RS09075
uniprot id: E8UWB3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

509193:THEBR RS03400
gene id: 509193:THEBR_RS03400
uniprot id: E8UWJ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

509193:THEBR RS06615
gene id: 509193:THEBR_RS06615
uniprot id: E8UTJ7
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

509193:THEBR RS11540
gene id: 509193:THEBR_RS11540
uniprot id: E8USK5
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

509193:THEBR RS09510
gene id: 509193:THEBR_RS09510
uniprot id: E8UWR5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

509193:THEBR RS08340
gene id: 509193:THEBR_RS08340
uniprot id: E8UVH8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS06685
gene id: 509193:THEBR_RS06685
uniprot id: E8UTL1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

509193:THEBR RS01835
gene id: 509193:THEBR_RS01835
uniprot id: E8UUX1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

509193:THEBR RS10725
gene id: 509193:THEBR_RS10725
uniprot id: E8URQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

509193:THEBR RS01195
gene id: 509193:THEBR_RS01195
uniprot id: E8UU56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

509193:THEBR RS06170
gene id: 509193:THEBR_RS06170
uniprot id: E8UT29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

509193:THEBR RS02255
gene id: 509193:THEBR_RS02255
uniprot id: E8UVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS01850
gene id: 509193:THEBR_RS01850
uniprot id: E8UUX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

509193:THEBR RS06690
gene id: 509193:THEBR_RS06690
uniprot id: E8UTL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

509193:THEBR RS02950
gene id: 509193:THEBR_RS02950
uniprot id: E8UW36
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

509193:THEBR RS08700
gene id: 509193:THEBR_RS08700
uniprot id: E8UVW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

509193:THEBR RS10140
gene id: 509193:THEBR_RS10140
uniprot id: E8UQZ1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS04555
gene id: 509193:THEBR_RS04555
uniprot id: E8URH4
names: Similarity
messages: Belongs to the TrpC family.

509193:THEBR RS09535
gene id: 509193:THEBR_RS09535
uniprot id: E8UWS0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

509193:THEBR RS02530
gene id: 509193:THEBR_RS02530
uniprot id: E8UVM7
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

509193:THEBR RS02520
gene id: 509193:THEBR_RS02520
uniprot id: E8UVM5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

509193:THEBR RS07365
gene id: 509193:THEBR_RS07365
uniprot id: E8UUD6
names: Similarity
messages: Belongs to the transpeptidase family.

509193:THEBR RS10980
gene id: 509193:THEBR_RS10980
uniprot id: E8US23
names: Similarity
messages: Belongs to the class-I fumarase family.

509193:THEBR RS01940
gene id: 509193:THEBR_RS01940
uniprot id: E8UUZ2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

509193:THEBR RS06405
gene id: 509193:THEBR_RS06405
uniprot id: E8UTF5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

509193:THEBR RS01875
gene id: 509193:THEBR_RS01875
uniprot id: E8UUX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

509193:THEBR RS11485
gene id: 509193:THEBR_RS11485
uniprot id: E8USJ4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

509193:THEBR RS00705
gene id: 509193:THEBR_RS00705
uniprot id: E8UTP1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

509193:THEBR RS02285
gene id: 509193:THEBR_RS02285
uniprot id: E8UVB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

509193:THEBR RS02685
gene id: 509193:THEBR_RS02685
uniprot id: E8UVQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

509193:THEBR RS04410
gene id: 509193:THEBR_RS04410
uniprot id: E8URE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

509193:THEBR RS02575
gene id: 509193:THEBR_RS02575
uniprot id: E8UVN6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

509193:THEBR RS09780
gene id: 509193:THEBR_RS09780
uniprot id: E8UWW3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

509193:THEBR RS03215
gene id: 509193:THEBR_RS03215
uniprot id: E8UW88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS03980
gene id: 509193:THEBR_RS03980
uniprot id: E8UQR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

509193:THEBR RS06830
gene id: 509193:THEBR_RS06830
uniprot id: E8UTW1
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

509193:THEBR RS07645
gene id: 509193:THEBR_RS07645
uniprot id: E8UUR0
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

509193:THEBR RS03410
gene id: 509193:THEBR_RS03410
uniprot id: E8UWK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

509193:THEBR RS04910
gene id: 509193:THEBR_RS04910
uniprot id: E8URW8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

509193:THEBR RS01885
gene id: 509193:THEBR_RS01885
uniprot id: E8UUY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

509193:THEBR RS03555
gene id: 509193:THEBR_RS03555
uniprot id: E8UWM9
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

509193:THEBR RS09750
gene id: 509193:THEBR_RS09750
uniprot id: E8UWV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

509193:THEBR RS10575
gene id: 509193:THEBR_RS10575
uniprot id: E8URE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

509193:THEBR RS06050
gene id: 509193:THEBR_RS06050
uniprot id: E8UT05
names: Similarity
messages: Belongs to the CinA family.

509193:THEBR RS06575
gene id: 509193:THEBR_RS06575
uniprot id: E8UTI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS09275
gene id: 509193:THEBR_RS09275
uniprot id: E8UWE9
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

509193:THEBR RS01035
gene id: 509193:THEBR_RS01035
uniprot id: E8UU25
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

509193:THEBR RS10100
gene id: 509193:THEBR_RS10100
uniprot id: E8UQY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

509193:THEBR RS06310
gene id: 509193:THEBR_RS06310
uniprot id: E8UTD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

509193:THEBR RS03375
gene id: 509193:THEBR_RS03375
uniprot id: E8UWJ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS01470
gene id: 509193:THEBR_RS01470
uniprot id: E8UUH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

509193:THEBR RS11075
gene id: 509193:THEBR_RS11075
uniprot id: E8US42
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

509193:THEBR RS05235
gene id: 509193:THEBR_RS05235
uniprot id: E8USA1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

509193:THEBR RS09670
gene id: 509193:THEBR_RS09670
uniprot id: E8UWU2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

509193:THEBR RS04570
gene id: 509193:THEBR_RS04570
uniprot id: E8URH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

509193:THEBR RS05505
gene id: 509193:THEBR_RS05505
uniprot id: E8USF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

509193:THEBR RS08395
gene id: 509193:THEBR_RS08395
uniprot id: E8UVI8
names: Similarity
messages: Belongs to the ThiD family.

509193:THEBR RS03150
gene id: 509193:THEBR_RS03150
uniprot id: E8UW76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS09545
gene id: 509193:THEBR_RS09545
uniprot id: E8UWS2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

509193:THEBR RS01895
gene id: 509193:THEBR_RS01895
uniprot id: E8UUY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

509193:THEBR RS07455
gene id: 509193:THEBR_RS07455
uniprot id: E8UUF4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

509193:THEBR RS10680
gene id: 509193:THEBR_RS10680
uniprot id: E8URP1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

509193:THEBR RS06485
gene id: 509193:THEBR_RS06485
uniprot id: E8UTH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

509193:THEBR RS07420
gene id: 509193:THEBR_RS07420
uniprot id: E8UUE7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

509193:THEBR RS04905
gene id: 509193:THEBR_RS04905
uniprot id: E8URW7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

509193:THEBR RS09180
gene id: 509193:THEBR_RS09180
uniprot id: E8UWD2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

509193:THEBR RS03465
gene id: 509193:THEBR_RS03465
uniprot id: E8UWL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

509193:THEBR RS11415
gene id: 509193:THEBR_RS11415
uniprot id: E8USI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

509193:THEBR RS03350
gene id: 509193:THEBR_RS03350
uniprot id: E8UWI6
names: Similarity
messages: Belongs to the UPF0251 family.

509193:THEBR RS03420
gene id: 509193:THEBR_RS03420
uniprot id: E8UWK2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

509193:THEBR RS11150
gene id: 509193:THEBR_RS11150
uniprot id: E8US52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

509193:THEBR RS01270
gene id: 509193:THEBR_RS01270
uniprot id: E8UU69
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

509193:THEBR RS05350
gene id: 509193:THEBR_RS05350
uniprot id: E8USC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

509193:THEBR RS02695
gene id: 509193:THEBR_RS02695
uniprot id: E8UVR0
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

509193:THEBR RS06545
gene id: 509193:THEBR_RS06545
uniprot id: E8UTI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

509193:THEBR RS05160
gene id: 509193:THEBR_RS05160
uniprot id: E8US17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

509193:THEBR RS11385
gene id: 509193:THEBR_RS11385
uniprot id: E8USH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

509193:THEBR RS03395
gene id: 509193:THEBR_RS03395
uniprot id: E8UWJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

509193:THEBR RS01355
gene id: 509193:THEBR_RS01355
uniprot id: E8UUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS09935
gene id: 509193:THEBR_RS09935
uniprot id: E8UQV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

509193:THEBR RS08015
gene id: 509193:THEBR_RS08015
uniprot id: E8UV51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

509193:THEBR RS01795
gene id: 509193:THEBR_RS01795
uniprot id: E8UUW3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

509193:THEBR RS09640
gene id: 509193:THEBR_RS09640
uniprot id: E8UWT6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

509193:THEBR RS00065
gene id: 509193:THEBR_RS00065
uniprot id: E8USV8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS06115
gene id: 509193:THEBR_RS06115
uniprot id: E8UT18
names: Similarity
messages: Belongs to the ribF family.

509193:THEBR RS05730
gene id: 509193:THEBR_RS05730
uniprot id: E8USQ9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

509193:THEBR RS00750
gene id: 509193:THEBR_RS00750
uniprot id: E8UTQ0
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

509193:THEBR RS03935
gene id: 509193:THEBR_RS03935
uniprot id: E8UQQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

509193:THEBR RS07405
gene id: 509193:THEBR_RS07405
uniprot id: E8UUE4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

509193:THEBR RS06605
gene id: 509193:THEBR_RS06605
uniprot id: E8UTJ5
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

509193:THEBR RS05365
gene id: 509193:THEBR_RS05365
uniprot id: E8USC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

509193:THEBR RS09775
gene id: 509193:THEBR_RS09775
uniprot id: E8UWW2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

509193:THEBR RS05935
gene id: 509193:THEBR_RS05935
uniprot id: E8USY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

509193:THEBR RS06410
gene id: 509193:THEBR_RS06410
uniprot id: E8UTF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

509193:THEBR RS11620
gene id: 509193:THEBR_RS11620
uniprot id: E8USM1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

509193:THEBR RS05510
gene id: 509193:THEBR_RS05510
uniprot id: E8USF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

509193:THEBR RS07920
gene id: 509193:THEBR_RS07920
uniprot id: E8UV32
names: Similarity
messages: Belongs to the phosphohexose mutase family.

509193:THEBR RS06095
gene id: 509193:THEBR_RS06095
uniprot id: E8UT14
names: Similarity
messages: Belongs to the peptidase M16 family.

509193:THEBR RS04560
gene id: 509193:THEBR_RS04560
uniprot id: E8URH5
names: Similarity
messages: Belongs to the TrpF family.

509193:THEBR RS06465
gene id: 509193:THEBR_RS06465
uniprot id: E8UTG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

509193:THEBR RS02270
gene id: 509193:THEBR_RS02270
uniprot id: E8UVB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS08780
gene id: 509193:THEBR_RS08780
uniprot id: E8UVX8
names: Similarity
messages: Belongs to the peptidase S8 family.

509193:THEBR RS07605
gene id: 509193:THEBR_RS07605
uniprot id: E8UUQ2
names: Similarity
messages: Belongs to the glutamine synthetase family.

509193:THEBR RS01920
gene id: 509193:THEBR_RS01920
uniprot id: E8UUY8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

509193:THEBR RS03120
gene id: 509193:THEBR_RS03120
uniprot id: E8UW70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS09150
gene id: 509193:THEBR_RS09150
uniprot id: E8UWC5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

509193:THEBR RS00935
gene id: 509193:THEBR_RS00935
uniprot id: E8UTT4
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

509193:THEBR RS00005
gene id: 509193:THEBR_RS00005
uniprot id: E8USU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

509193:THEBR RS10510
gene id: 509193:THEBR_RS10510
uniprot id: E8URD1
names: Function
messages: Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.

509193:THEBR RS03945
gene id: 509193:THEBR_RS03945
uniprot id: E8UQQ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

509193:THEBR RS04070
gene id: 509193:THEBR_RS04070
uniprot id: E8UR06
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

509193:THEBR RS08440
gene id: 509193:THEBR_RS08440
uniprot id: E8UVJ7
names: Similarity
messages: Belongs to the glutamine synthetase family.

509193:THEBR RS09290
gene id: 509193:THEBR_RS09290
uniprot id: E8UWF2
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS05700
gene id: 509193:THEBR_RS05700
uniprot id: E8USQ3
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

509193:THEBR RS00745
gene id: 509193:THEBR_RS00745
uniprot id: E8UTP9
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

509193:THEBR RS04240
gene id: 509193:THEBR_RS04240
uniprot id: E8UR40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

509193:THEBR RS05595
gene id: 509193:THEBR_RS05595
uniprot id: E8USN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

509193:THEBR RS04035
gene id: 509193:THEBR_RS04035
uniprot id: E8UQZ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

509193:THEBR RS05395
gene id: 509193:THEBR_RS05395
uniprot id: E8USD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

509193:THEBR RS03870
gene id: 509193:THEBR_RS03870
uniprot id: E8UQP6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

509193:THEBR RS01255
gene id: 509193:THEBR_RS01255
uniprot id: E8UU66
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS01900
gene id: 509193:THEBR_RS01900
uniprot id: E8UUY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

509193:THEBR RS10275
gene id: 509193:THEBR_RS10275
uniprot id: E8UR91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

509193:THEBR RS06430
gene id: 509193:THEBR_RS06430
uniprot id: E8UTG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

509193:THEBR RS04155
gene id: 509193:THEBR_RS04155
uniprot id: E8UR23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

509193:THEBR RS08865
gene id: 509193:THEBR_RS08865
uniprot id: E8UVZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

509193:THEBR RS01440
gene id: 509193:THEBR_RS01440
uniprot id: E8UUH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

509193:THEBR RS04630
gene id: 509193:THEBR_RS04630
uniprot id: E8URI8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

509193:THEBR RS06470
gene id: 509193:THEBR_RS06470
uniprot id: E8UTG8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

509193:THEBR RS03835
gene id: 509193:THEBR_RS03835
uniprot id: E8UQP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

509193:THEBR RS08755
gene id: 509193:THEBR_RS08755
uniprot id: E8UVX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

509193:THEBR RS04300
gene id: 509193:THEBR_RS04300
uniprot id: E8UR52
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

509193:THEBR RS01010
gene id: 509193:THEBR_RS01010
uniprot id: E8UU21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS00820
gene id: 509193:THEBR_RS00820
uniprot id: E8UTR1
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

509193:THEBR RS08850
gene id: 509193:THEBR_RS08850
uniprot id: E8UVZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

509193:THEBR RS05215
gene id: 509193:THEBR_RS05215
uniprot id: E8US97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

509193:THEBR RS08880
gene id: 509193:THEBR_RS08880
uniprot id: E8UVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

509193:THEBR RS05880
gene id: 509193:THEBR_RS05880
uniprot id: E8UST9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

509193:THEBR RS10600
gene id: 509193:THEBR_RS10600
uniprot id: E8URM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS11510
gene id: 509193:THEBR_RS11510
uniprot id: E8USJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

509193:THEBR RS05185
gene id: 509193:THEBR_RS05185
uniprot id: E8US90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

509193:THEBR RS07690
gene id: 509193:THEBR_RS07690
uniprot id: E8UUR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

509193:THEBR RS10295
gene id: 509193:THEBR_RS10295
uniprot id: E8UR95
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

509193:THEBR RS02445
gene id: 509193:THEBR_RS02445
uniprot id: E8UVE8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

509193:THEBR RS08010
gene id: 509193:THEBR_RS08010
uniprot id: E8UV50
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

509193:THEBR RS04140
gene id: 509193:THEBR_RS04140
uniprot id: E8UR20
names: Similarity
messages: Belongs to the transpeptidase family.

509193:THEBR RS05770
gene id: 509193:THEBR_RS05770
uniprot id: E8USR7
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS06645
gene id: 509193:THEBR_RS06645
uniprot id: E8UTK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

509193:THEBR RS00215
gene id: 509193:THEBR_RS00215
uniprot id: E8UT67
names: Similarity
messages: Belongs to the UPF0175 family.

509193:THEBR RS09030
gene id: 509193:THEBR_RS09030
uniprot id: E8UWA4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

509193:THEBR RS01995
gene id: 509193:THEBR_RS01995
uniprot id: E8UV03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

509193:THEBR RS10720
gene id: 509193:THEBR_RS10720
uniprot id: E8URP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

509193:THEBR RS03930
gene id: 509193:THEBR_RS03930
uniprot id: E8UQQ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS10710
gene id: 509193:THEBR_RS10710
uniprot id: E8URP7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

509193:THEBR RS06065
gene id: 509193:THEBR_RS06065
uniprot id: E8UT08
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Cell membrane
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

509193:THEBR RS08995
gene id: 509193:THEBR_RS08995
uniprot id: E8UW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

509193:THEBR RS00815
gene id: 509193:THEBR_RS00815
uniprot id: E8UTR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

509193:THEBR RS06315
gene id: 509193:THEBR_RS06315
uniprot id: E8UTD7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

509193:THEBR RS03735
gene id: 509193:THEBR_RS03735
uniprot id: E8UQM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

509193:THEBR RS09100
gene id: 509193:THEBR_RS09100
uniprot id: E8UWB8
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

509193:THEBR RS02660
gene id: 509193:THEBR_RS02660
uniprot id: E8UVQ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

509193:THEBR RS01535
gene id: 509193:THEBR_RS01535
uniprot id: E8UUI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

509193:THEBR RS09840
gene id: 509193:THEBR_RS09840
uniprot id: E8UQT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS00035
gene id: 509193:THEBR_RS00035
uniprot id: E8USV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

509193:THEBR RS10560
gene id: 509193:THEBR_RS10560
uniprot id: E8URE0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

509193:THEBR RS03485
gene id: 509193:THEBR_RS03485
uniprot id: E8UWL5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

509193:THEBR RS04925
gene id: 509193:THEBR_RS04925
uniprot id: E8URX1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

509193:THEBR RS08605
gene id: 509193:THEBR_RS08605
uniprot id: E8UVL7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

509193:THEBR RS02920
gene id: 509193:THEBR_RS02920
uniprot id: E8UW30
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

509193:THEBR RS09380
gene id: 509193:THEBR_RS09380
uniprot id: E8UWH0
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS00050
gene id: 509193:THEBR_RS00050
uniprot id: E8USV5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

509193:THEBR RS01530
gene id: 509193:THEBR_RS01530
uniprot id: E8UUI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

509193:THEBR RS02715
gene id: 509193:THEBR_RS02715
uniprot id: E8UVR4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

509193:THEBR RS01715
gene id: 509193:THEBR_RS01715
uniprot id: E8UUM5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

509193:THEBR RS04130
gene id: 509193:THEBR_RS04130
uniprot id: E8UR18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

509193:THEBR RS05385
gene id: 509193:THEBR_RS05385
uniprot id: E8USD2
names: Similarity
messages: Belongs to the UPF0342 family.

509193:THEBR RS02585
gene id: 509193:THEBR_RS02585
uniprot id: E8UVN8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

509193:THEBR RS06515
gene id: 509193:THEBR_RS06515
uniprot id: E8UTH7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

509193:THEBR RS05230
gene id: 509193:THEBR_RS05230
uniprot id: E8USA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

509193:THEBR RS09070
gene id: 509193:THEBR_RS09070
uniprot id: E8UWB2
names: Similarity
messages: Belongs to the bacterial flagellin family.

509193:THEBR RS08895
gene id: 509193:THEBR_RS08895
uniprot id: E8UW01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

509193:THEBR RS00860
gene id: 509193:THEBR_RS00860
uniprot id: E8UTR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

509193:THEBR RS06060
gene id: 509193:THEBR_RS06060
uniprot id: E8UT07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

509193:THEBR RS10400
gene id: 509193:THEBR_RS10400
uniprot id: E8URA8
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

509193:THEBR RS10260
gene id: 509193:THEBR_RS10260
uniprot id: E8UR88
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS10505
gene id: 509193:THEBR_RS10505
uniprot id: E8URD0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

509193:THEBR RS01860
gene id: 509193:THEBR_RS01860
uniprot id: E8UUX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

509193:THEBR RS04535
gene id: 509193:THEBR_RS04535
uniprot id: E8URH0
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

509193:THEBR RS04835
gene id: 509193:THEBR_RS04835
uniprot id: E8URV3
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS03940
gene id: 509193:THEBR_RS03940
uniprot id: E8UQQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

509193:THEBR RS01165
gene id: 509193:THEBR_RS01165
uniprot id: E8UU51
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS07085
gene id: 509193:THEBR_RS07085
uniprot id: E8UU84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

509193:THEBR RS11565
gene id: 509193:THEBR_RS11565
uniprot id: E8USL0
names: Similarity
messages: Belongs to the ParB family.

509193:THEBR RS08635
gene id: 509193:THEBR_RS08635
uniprot id: E8UVU8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

509193:THEBR RS04010
gene id: 509193:THEBR_RS04010
uniprot id: E8UQR8
names: Similarity
messages: Belongs to the peptidase M18 family.

509193:THEBR RS04245
gene id: 509193:THEBR_RS04245
uniprot id: E8UR41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

509193:THEBR RS07075
gene id: 509193:THEBR_RS07075
uniprot id: E8UU82
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

509193:THEBR RS09310
gene id: 509193:THEBR_RS09310
uniprot id: E8UWF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

509193:THEBR RS10735
gene id: 509193:THEBR_RS10735
uniprot id: E8URQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

509193:THEBR RS01495
gene id: 509193:THEBR_RS01495
uniprot id: E8UUI4
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

509193:THEBR RS02655
gene id: 509193:THEBR_RS02655
uniprot id: E8UVQ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

509193:THEBR RS05975
gene id: 509193:THEBR_RS05975
uniprot id: E8USZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

509193:THEBR RS05360
gene id: 509193:THEBR_RS05360
uniprot id: E8USC7
names: Similarity
messages: Belongs to the UPF0297 family.

509193:THEBR RS01485
gene id: 509193:THEBR_RS01485
uniprot id: E8UUI2
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS01830
gene id: 509193:THEBR_RS01830
uniprot id: E8UUX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

509193:THEBR RS04210
gene id: 509193:THEBR_RS04210
uniprot id: E8UR34
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

509193:THEBR RS00960
gene id: 509193:THEBR_RS00960
uniprot id: E8UU11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

509193:THEBR RS06460
gene id: 509193:THEBR_RS06460
uniprot id: E8UTG6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

509193:THEBR RS05450
gene id: 509193:THEBR_RS05450
uniprot id: E8USE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

509193:THEBR RS05990
gene id: 509193:THEBR_RS05990
uniprot id: E8USZ3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

509193:THEBR RS07310
gene id: 509193:THEBR_RS07310
uniprot id: E8UUC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

509193:THEBR RS07270
gene id: 509193:THEBR_RS07270
uniprot id: E8UUB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

509193:THEBR RS10045
gene id: 509193:THEBR_RS10045
uniprot id: E8UQX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

509193:THEBR RS04510
gene id: 509193:THEBR_RS04510
uniprot id: E8URG5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

509193:THEBR RS11545
gene id: 509193:THEBR_RS11545
uniprot id: E8USK6
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

509193:THEBR RS09815
gene id: 509193:THEBR_RS09815
uniprot id: E8UQS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS03090
gene id: 509193:THEBR_RS03090
uniprot id: E8UW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

509193:THEBR RS03490
gene id: 509193:THEBR_RS03490
uniprot id: E8UWL6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

509193:THEBR RS09925
gene id: 509193:THEBR_RS09925
uniprot id: E8UQU9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

509193:THEBR RS07905
gene id: 509193:THEBR_RS07905
uniprot id: E8UV29
names: Similarity
messages: Belongs to the CpsD/CapB family.

509193:THEBR RS06835
gene id: 509193:THEBR_RS06835
uniprot id: E8UTW2
names: Similarity
messages: Belongs to the HypE family.

509193:THEBR RS05140
gene id: 509193:THEBR_RS05140
uniprot id: E8US13
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

509193:THEBR RS03705
gene id: 509193:THEBR_RS03705
uniprot id: E8UQL8
names: Similarity
messages: Belongs to the acylphosphatase family.

509193:THEBR RS00715
gene id: 509193:THEBR_RS00715
uniprot id: E8UTP3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

509193:THEBR RS10730
gene id: 509193:THEBR_RS10730
uniprot id: E8URQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

509193:THEBR RS06395
gene id: 509193:THEBR_RS06395
uniprot id: E8UTF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

509193:THEBR RS07775
gene id: 509193:THEBR_RS07775
uniprot id: E8UUT2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

509193:THEBR RS03715
gene id: 509193:THEBR_RS03715
uniprot id: E8UQM0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

509193:THEBR RS02310
gene id: 509193:THEBR_RS02310
uniprot id: E8UVC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

509193:THEBR RS01150
gene id: 509193:THEBR_RS01150
uniprot id: E8UU48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

509193:THEBR RS07170
gene id: 509193:THEBR_RS07170
uniprot id: E8UUA1
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

509193:THEBR RS04055
gene id: 509193:THEBR_RS04055
uniprot id: E8UR03
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

509193:THEBR RS00270
gene id: 509193:THEBR_RS00270
uniprot id: E8UT78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

509193:THEBR RS00595
gene id: 509193:THEBR_RS00595
uniprot id: E8UTM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

509193:THEBR RS07795
gene id: 509193:THEBR_RS07795
uniprot id: E8UUT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

509193:THEBR RS09970
gene id: 509193:THEBR_RS09970
uniprot id: E8UQV8
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

509193:THEBR RS06815
gene id: 509193:THEBR_RS06815
uniprot id: E8UTV8
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

509193:THEBR RS04600
gene id: 509193:THEBR_RS04600
uniprot id: E8URI3
names: Similarity
messages: Belongs to the UPF0047 family.

509193:THEBR RS09340
gene id: 509193:THEBR_RS09340
uniprot id: E8UWG2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

509193:THEBR RS01030
gene id: 509193:THEBR_RS01030
uniprot id: E8UU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS06155
gene id: 509193:THEBR_RS06155
uniprot id: E8UT26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

509193:THEBR RS09950
gene id: 509193:THEBR_RS09950
uniprot id: E8UQV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

509193:THEBR RS02450
gene id: 509193:THEBR_RS02450
uniprot id: E8UVE9
names: Similarity
messages: Belongs to the EamA transporter family.

509193:THEBR RS05400
gene id: 509193:THEBR_RS05400
uniprot id: E8USD5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS03950
gene id: 509193:THEBR_RS03950
uniprot id: E8UQQ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

509193:THEBR RS04385
gene id: 509193:THEBR_RS04385
uniprot id: E8UR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

509193:THEBR RS03305
gene id: 509193:THEBR_RS03305
uniprot id: E8UWH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

509193:THEBR RS00680
gene id: 509193:THEBR_RS00680
uniprot id: E8UTN6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

509193:THEBR RS09565
gene id: 509193:THEBR_RS09565
uniprot id: E8UWS6
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS11520
gene id: 509193:THEBR_RS11520
uniprot id: E8USK1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

509193:THEBR RS04310
gene id: 509193:THEBR_RS04310
uniprot id: E8UR54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

509193:THEBR RS07120
gene id: 509193:THEBR_RS07120
uniprot id: E8UU91
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

509193:THEBR RS07915
gene id: 509193:THEBR_RS07915
uniprot id: E8UV31
names: Similarity
messages: Belongs to the UDPGP type 2 family.

509193:THEBR RS05145
gene id: 509193:THEBR_RS05145
uniprot id: E8US14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

509193:THEBR RS09010
gene id: 509193:THEBR_RS09010
uniprot id: E8UWA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

509193:THEBR RS05180
gene id: 509193:THEBR_RS05180
uniprot id: E8US89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

509193:THEBR RS09940
gene id: 509193:THEBR_RS09940
uniprot id: E8UQV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS06330
gene id: 509193:THEBR_RS06330
uniprot id: E8UTE0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

509193:THEBR RS10210
gene id: 509193:THEBR_RS10210
uniprot id: E8UR79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

509193:THEBR RS01840
gene id: 509193:THEBR_RS01840
uniprot id: E8UUX2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

509193:THEBR RS04565
gene id: 509193:THEBR_RS04565
uniprot id: E8URH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

509193:THEBR RS05985
gene id: 509193:THEBR_RS05985
uniprot id: E8USZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

509193:THEBR RS05735
gene id: 509193:THEBR_RS05735
uniprot id: E8USR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS09680
gene id: 509193:THEBR_RS09680
uniprot id: E8UWU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

509193:THEBR RS02275
gene id: 509193:THEBR_RS02275
uniprot id: E8UVB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

509193:THEBR RS10410
gene id: 509193:THEBR_RS10410
uniprot id: E8URB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

509193:THEBR RS02555
gene id: 509193:THEBR_RS02555
uniprot id: E8UVN2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

509193:THEBR RS11410
gene id: 509193:THEBR_RS11410
uniprot id: E8USH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

509193:THEBR RS05930
gene id: 509193:THEBR_RS05930
uniprot id: E8USY1
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

509193:THEBR RS02065
gene id: 509193:THEBR_RS02065
uniprot id: E8UV17
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

509193:THEBR RS04000
gene id: 509193:THEBR_RS04000
uniprot id: E8UQR6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

509193:THEBR RS02055
gene id: 509193:THEBR_RS02055
uniprot id: E8UV15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

509193:THEBR RS11395
gene id: 509193:THEBR_RS11395
uniprot id: E8USH6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

509193:THEBR RS08360
gene id: 509193:THEBR_RS08360
uniprot id: E8UVI2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

509193:THEBR RS04505
gene id: 509193:THEBR_RS04505
uniprot id: E8URG4
names: Subcellular Location Annotation
messages: Membrane

509193:THEBR RS06930
gene id: 509193:THEBR_RS06930
uniprot id: E8UTX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

509193:THEBR RS09385
gene id: 509193:THEBR_RS09385
uniprot id: E8UWH1
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

509193:THEBR RS05050
gene id: 509193:THEBR_RS05050
uniprot id: E8URZ7
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

509193:THEBR RS02045
gene id: 509193:THEBR_RS02045
uniprot id: E8UV13
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

509193:THEBR RS00070
gene id: 509193:THEBR_RS00070
uniprot id: E8USV9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

509193:THEBR RS07175
gene id: 509193:THEBR_RS07175
uniprot id: E8UUA2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

509193:THEBR RS05000
gene id: 509193:THEBR_RS05000
uniprot id: E8URY6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

509193:THEBR RS11035
gene id: 509193:THEBR_RS11035
uniprot id: E8US33
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

509193:THEBR RS06105
gene id: 509193:THEBR_RS06105
uniprot id: E8UT16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

509193:THEBR RS06705
gene id: 509193:THEBR_RS06705
uniprot id: E8UTT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

509193:THEBR RS05835
gene id: 509193:THEBR_RS05835
uniprot id: E8UST0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

509193:THEBR RS02590
gene id: 509193:THEBR_RS02590
uniprot id: E8UVN9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

509193:THEBR RS03720
gene id: 509193:THEBR_RS03720
uniprot id: E8UQM1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

509193:THEBR RS09420
gene id: 509193:THEBR_RS09420
uniprot id: E8UWQ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

509193:THEBR RS07350
gene id: 509193:THEBR_RS07350
uniprot id: E8UUD3
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

509193:THEBR RS10795
gene id: 509193:THEBR_RS10795
uniprot id: E8URR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

509193:THEBR RS08260
gene id: 509193:THEBR_RS08260
uniprot id: E8UVG4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

509193:THEBR RS06175
gene id: 509193:THEBR_RS06175
uniprot id: E8UT30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

509193:THEBR RS09005
gene id: 509193:THEBR_RS09005
uniprot id: E8UW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

509193:THEBR RS06010
gene id: 509193:THEBR_RS06010
uniprot id: E8USZ7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

509193:THEBR RS08980
gene id: 509193:THEBR_RS08980
uniprot id: E8UW18
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

509193:THEBR RS08785
gene id: 509193:THEBR_RS08785
uniprot id: E8UVX9
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

509193:THEBR RS07860
gene id: 509193:THEBR_RS07860
uniprot id: E8UV20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

509193:THEBR RS00615
gene id: 509193:THEBR_RS00615
uniprot id: E8UTM4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

509193:THEBR RS02005
gene id: 509193:THEBR_RS02005
uniprot id: E8UV05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

509193:THEBR RS06755
gene id: 509193:THEBR_RS06755
uniprot id: E8UTU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

509193:THEBR RS10300
gene id: 509193:THEBR_RS10300
uniprot id: E8UR96
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.