The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
Belongs to the universal ribosomal protein uL16 family.
Belongs to the glycosyl hydrolase 1 family.
Lacks conserved residue(s) required for the propagation of feature annotation.
Belongs to the YSL (TC 2.A.67.2) family.
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Belongs to the peroxidase family. Ascorbate peroxidase subfamily.
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.
In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
In the N-terminal section; belongs to the glutamate 5-kinase family.
P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants.
Belongs to the thioesterase PaaI family.
Belongs to the pectinacetylesterase family.
Hydrolyzes acetyl esters in homogalacturonan regions of pectin. In type I primary cell wall, galacturonic acid residues of pectin can be acetylated at the O-2 and O-3 positions. Decreasing the degree of acetylation of pectin gels in vitro alters their physical properties.
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Required for N-linked oligosaccharide assembly.
Belongs to the ubiquitin-activating E1 family.
The PPC domain mediates interactions between AHL proteins.
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).
Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
Belongs to the PEP-utilizing enzyme family.
Required for 60S pre-ribosomal subunits export to the cytoplasm.
Belongs to the protein kinase superfamily.
Belongs to the 'GDXG' lipolytic enzyme family.
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. TOC34 subfamily.
GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis.
Belongs to the trans-sulfuration enzymes family.
Functions in brassinosteroid signaling. May function as transcriptional repressor.
Belongs to the chalcone isomerase family.
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin.
Belongs to the eukaryotic diacylglycerol kinase family.
Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack.
Belongs to the glycosyl hydrolase 31 family.
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
In the C-terminal section; belongs to the MoeA family.
In the N-terminal section; belongs to the MoaB/Mog family.
Belongs to the ubiquitin-conjugating enzyme family.
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-7 subfamily.
Belongs to the methyltransferase superfamily.
Binds to multiple calmodulin (CaM) in the presence of Ca(2+) and CaM-like proteins.
Belongs to the 'GDSL' lipolytic enzyme family.
Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
Belongs to the eukaryotic ribosomal protein eL28 family.
Catalyzes the oxidation of mono- and o-diphenols to o-diquinones.
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.
Belongs to the acireductone dioxygenase (ARD) family.
Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
Belongs to the phospholipid scramblase family.
Belongs to the tRNA(His) guanylyltransferase family.
Belongs to the phosphoglycerate kinase family.
Belongs to the glycosyltransferase 47 family.
Belongs to the UbiA prenyltransferase family.
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
Belongs to the LanC-like protein family.
Belongs to the Casparian strip membrane proteins (CASP) family.
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
Belongs to the major facilitator superfamily. phosphate:H(+) symporter (TC 2.A.1.9) family.
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
GTPase involved in pre-60S ribosomal subunit maturation.
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Belongs to the potassium channel family. Plant (TC 1.A.1.4) subfamily.
The KHA domain (rich in hydrophobic and acidic residues) present in the C-terminal part is likely to be important for tetramerization.
The potassium channel is composed of a homo- or heterotetrameric complex of pore-forming subunits.
The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids. The pore-forming region H5 is enclosed by the transmembrane segments S5 and S6 in the Shaker-type (1P/6TM) and contains the GYGD signature motif which seems to be involved in potassium selectivity.
Transcriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes.
Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.
Belongs to the acyl carrier protein (ACP) family.
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
Belongs to the small heat shock protein (HSP20) family.
May be involved in environmental stress response.
Belongs to the phosphatase 2A regulatory subunit.
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Belongs to the proteasome subunit S3 family.
Belongs to the inositol polyphosphate 5-phosphatase family.
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Belongs to the mitochondrion-specific ribosomal protein mL53 family.
Belongs to the universal ribosomal protein uS5 family.
Belongs to the glycosyl hydrolase 14 family.
Belongs to the expansin family. Expansin A subfamily.
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found.
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
Belongs to the MoaE family. MOCS2B subfamily.
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Belongs to the ATPase epsilon chain family.
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
Belongs to the protein disulfide isomerase family.
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Belongs to the phosphoribulokinase family.
The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.
In the N-terminal section; belongs to the long-chain O-acyltransferase family.
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Belongs to the glycosyl hydrolase 32 family.
Belongs to the PC-esterase family. TBL subfamily.
Belongs to the glycosyl hydrolase 28 family.
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
Belongs to the glycosyl hydrolase 17 family.
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
Converts the prephenate produced from the shikimate-chorismate pathway into phenylalanine.
Proteolytically removes the C-terminal three residues of farnesylated proteins.
Acylhydrolase that catalyzes the hydrolysis of phospholipids at the sn-1 position.
Belongs to the AB hydrolase superfamily. Lipase family.
Belongs to the RING-type zinc finger family. ATL subfamily.
Belongs to the PPR family. PCMP-H subfamily.
Golgi membrane protein involved in vesicular trafficking.
Belongs to the complex I 20 kDa subunit family.
Participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria). This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI.
Belongs to the small GTPase superfamily. Rho family.
Catalyzes the exchange of ADP and ATP across the membrane.
Belongs to the eukaryotic ribosomal protein eL19 family.
Belongs to the PYR/PYL/RCAR abscisic acid intracellular receptor family.
In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
In the N-terminal section; belongs to the leguminous lectin family.
Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Belongs to the complex I NDUFA12 subunit family.
Belongs to the pseudouridine synthase RsuA family.
May promote appropriate targeting of ribosome-nascent polypeptide complexes.
Belongs to the glycosyltransferase GT106 family.
Belongs to the strictosidine synthase family.
Belongs to the heat shock protein 90 family.
Belongs to the glutaredoxin family. CC-type subfamily.
Belongs to the LDH/MDH superfamily. LDH family.
Belongs to the phosphohexose mutase family.
Interconverts GlcNAc-6-P and GlcNAc-1-P.
Belongs to the universal ribosomal protein uS15 family.
Belongs to the argonaute family. Ago subfamily.
Belongs to the V-ATPase V0D/AC39 subunit family.
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Belongs to the fasciclin-like AGP family.
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Belongs to the TRAPP small subunits family. BET3 subfamily.
Belongs to the purine permeases (TC 2.A.7.14) family.
Belongs to the U2 small nuclear ribonucleoprotein A family.
Belongs to the DEAD box helicase family.
Belongs to the peptidase M67A family. CSN6 subfamily.
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
Belongs to the heat shock protein 70 family.
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
Belongs to the beta-class carbonic anhydrase family.
Belongs to the NFYA/HAP2 subunit family.
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
Belongs to the plant cysteine rich small secretory peptide family. Epidermal patterning factor subfamily.
Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.
Belongs to the cytidine and deoxycytidylate deaminase family.
Component of the 40S subunit of the ribosome.
In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
In the N-terminal section; belongs to the ubiquitin family.
Belongs to the AAA ATPase family. PCH2 subfamily.
Plays a key role in chromosome recombination during meiosis.
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Transcriptional repressor that regulates multiple aspects of plant growth and development.
Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
Belongs to the SWEET sugar transporter family.
Mediates both low-affinity uptake and efflux of sugar across the membrane.
Belongs to the bacterial ribosomal protein bS21 family.
Belongs to the multicopper oxidase family.
Lignin degradation and detoxification of lignin-derived products.
May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins.
Belongs to the UDP-glycosyltransferase family.
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.
Belongs to the ARR family. Type-B subfamily.
Transcriptional activator that binds specific DNA sequence.
Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
Binds 2 divalent ions per subunit. The metal ions interact primarily with the substrate. Can utilize magnesium, manganese or cobalt (in vitro).
Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
Belongs to the fatty acid desaturase CarF family.
Belongs to the sterol desaturase family.
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Belongs to the alternative oxidase family.
Belongs to the GMC oxidoreductase family.
Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
Probable GTP-binding protein that may be involved in cell development.
Belongs to the SINA (Seven in absentia) family.
Belongs to the plant ACBP60 protein family.
Belongs to the RBR family. Ariadne subfamily.
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.
Belongs to the formin-like family. Class-I subfamily.
In the C-terminal section; belongs to the peptidase M41 family.
In the N-terminal section; belongs to the AAA ATPase family.
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.
Belongs to the universal ribosomal protein uS17 family.
Belongs to the chaperonin (HSP60) family.
Belongs to the clathrin light chain family.
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Belongs to the cyclophilin-type PPIase family.
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Belongs to the DHHC palmitoyltransferase family.
The DHHC domain is required for palmitoyltransferase activity.
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Belongs to the fatty acid desaturase type 1 family.
The histidine box domains are involved in binding the catalytic metal ions.
Belongs to the ketol-acid reductoisomerase family.
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Binds 1 Mg(2+) or Mn(2+) ion per subunit.
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Belongs to the early nodulin-like (ENODL) family.
Belongs to the bacterial ribosomal protein bL12 family.
Belongs to the LOB domain-containing protein family.
In the C-terminal section; belongs to the pectinesterase family.
In the N-terminal section; belongs to the PMEI family.
Belongs to the phosphatidylethanolamine-binding protein family.
Belongs to the myo-inositol oxygenase family.
Belongs to the sulfotransferase 1 family.
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.
Belongs to the oligopeptide OPT transporter (TC 2.A.67.1) family.
Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts (By similarity). Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome (By similarity). Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
Belongs to the carbohydrate kinase PfkB family.
Belongs to the universal ribosomal protein uS12 family.
Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
The jas domain is required for interaction with COI1.
Belongs to the MIP/aquaporin (TC 1.A.8) family. SIP (TC 1.A.8.10) subfamily.
Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.
Belongs to the tRNA methyltransferase O family.
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
Belongs to the 3-hydroxybenzoate 6-hydroxylase family.
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Belongs to the eukaryotic ribosomal protein eS7 family.
Activated by threonine and tyrosine phosphorylation.
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms.
Belongs to the HD-ZIP homeobox family. Class I subfamily.
Belongs to the TALE/BELL homeobox family.
Belongs to the glycosyl hydrolase 16 family.
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.
Contains at least one intrachain disulfide bond essential for its enzymatic activity.
Belongs to the eukaryotic ribosomal protein eL13 family.
Belongs to the complex I NDUFS4 subunit family.
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
Belongs to the flavin monoamine oxidase family.
Belongs to the plant ureide permease (TC 2.A.7.19) family.
Belongs to the DNA2/NAM7 helicase family.
Belongs to the chloride channel (TC 2.A.49) family.
Belongs to the ribulose-phosphate 3-epimerase family.
Belongs to the glycosyltransferase 31 family.
Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
Component of the peroxisomal and mitochondrial division machineries. Plays a role in promoting the fission of mitochondria and peroxisomes.
The C-terminus is necessary for mitochondrial or peroxisomal targeting, while the N-terminus is necessary for mitochondrial or peroxisomal fission.
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
Glutamate-gated receptor that probably acts as non-selective cation channel.
Belongs to the myo-inositol 1-phosphate synthase family.
May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
Belongs to the polysaccharide lyase 1 family.
Binds 1 Ca(2+) ion. Required for its activity.
Belongs to the phospholipase D family. C2-PLD subfamily.
Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond.
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Maintains high levels of reduced glutathione.
Belongs to the eukaryotic mitochondrial porin (TC 1.B.8.1) family.
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
Belongs to the deoxyhypusine synthase family.
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
Belongs to the adaptor complexes large subunit family.
Belongs to the zinc-containing alcohol dehydrogenase family.
Component of the CCR4-NOT complex, at least composed of CRR4 and CAF1 proteins.
Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression.
Belongs to the methyltransferase superfamily. HEN1 family.
Belongs to the AAA ATPase family. BCS1 subfamily.
Belongs to the poly(A) polymerase family.
Belongs to the class-II aminoacyl-tRNA synthetase family.
Belongs to the acyl-CoA dehydrogenase family.
Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP.
Homodimer. Heterotetramer of two TOP6A and two TOP6B subunits.
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
Belongs to the uroporphyrinogen decarboxylase family.
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
Interacts with H3K4me3 and to a lesser extent with H3K4me2.
The PHD-type zinc finger mediates the binding to H3K4me3.
Belongs to the adenylosuccinate synthetase family.
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.
Belongs to the Cu-Zn superoxide dismutase family.
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Belongs to the universal ribosomal protein uS2 family.
Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21.
Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Belongs to the senescence regulator S40 family.
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily.
Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways.
Belongs to the diacylglycerol acyltransferase family.
Associates with 90S and pre-40S pre-ribosomal particles.
Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
Belongs to the universal ribosomal protein uS9 family.
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
Component of the Golgi-associated retrograde protein (GARP) complex.
Belongs to the MsrA Met sulfoxide reductase family.
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
Belongs to the terpene cyclase/mutase family.
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
Tetramer of 2 alpha and 2 beta subunits.
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
Belongs to the eukaryotic-type primase small subunit family.
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Belongs to the eukaryotic ribosomal protein eS24 family.
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.
In the C-terminal section; belongs to the UPRTase family.
In the N-terminal section; belongs to the uridine kinase family.
Binds 1 divalent metal cation per subunit.
Belongs to the class-I aminoacyl-tRNA synthetase family.
Belongs to the group II decarboxylase family.
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Belongs to the anthranilate synthase component I family.
Heterotetramer consisting of two non-identical subunits: a beta subunit and a large alpha subunit.
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Probably involved in membrane trafficking.
Belongs to the CDI family. ICK/KRP subfamily.
Belongs to the eukaryotic ATPase epsilon family.
Belongs to the PDK/BCKDK protein kinase family.
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Belongs to the HD-ZIP homeobox family. Class IV subfamily.
Belongs to the Orn/Lys/Arg decarboxylase class-II family.
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
Belongs to the universal ribosomal protein uS10 family.
Belongs to the universal ribosomal protein uL14 family.
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Belongs to the auxin efflux carrier (TC 2.A.69.1) family.
May act as a component of the auxin efflux carrier.
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore.
The RING-type zinc finger domain is responsible for E3 ligase activity.
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Belongs to the proteasome subunit S2 family.
Component of the 19S regulatory particle (RP/PA700) base subcomplex of the 26S proteasome. The 26S proteasome is composed of a core protease (CP), known as the 20S proteasome, capped at one or both ends by the 19S regulatory particle (RP/PA700). The RP/PA700 complex is composed of at least 17 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively.
Belongs to the phage and mitochondrial RNA polymerase family.
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Belongs to the TrkH potassium transport family. HKT (TC 2.A.38.3) subfamily.
In the C-terminal section; belongs to the trehalose phosphatase family.
In the N-terminal section; belongs to the glycosyltransferase 20 family.
Belongs to the 7S seed storage protein family.
Belongs to the purine-cytosine permease (2.A.39) family.
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Defense against chitin-containing fungal pathogens.
Belongs to the CTL (choline transporter-like) family.
Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
Belongs to the serine/threonine dehydratase family.
Catalyzes the conversion of threonine to alpha-keto butyrate in isoleucine (Ile) biosynthesis (PubMed:17085687). Required for JA-Ile biosynthesis, a signaling molecule involved in defense and resistance to the herbivore Manduca sexta caterpillars (PubMed:17085687).
Induced by methyl jasmonate and feeding with the herbivore Manduca sexta caterpillars.
Plants silencing TD exhibit a stunt growth phenotype.
Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
Belongs to the MORC ATPase protein family.
Belongs to the class II aldolase/RraA-like family.
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
Belongs to the snRNP Sm proteins family.
Component of LSM protein complexes, which are involved in RNA processing.
Component of the ribosomal small subunit (SSU) processome.
Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
Belongs to the thiolase-like superfamily. Thiolase family.
Belongs to the neutral ceramidase family.
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
Belongs to the EARLY FLOWERING 4 family.
The QLQ domain and WRC domain may be involved in protein-protein interaction and DNA-binding, respectively.
Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.
Belongs to the glycosyltransferase 4 family.
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
Belongs to the SNF2/RAD54 helicase family.
Component of the INO80 chromatin-remodeling complex.
The DBINO region is involved in binding to DNA.
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
Belongs to the 2Fe2S plant-type ferredoxin family.
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily.
Belongs to the GPI inositol-deacylase family.
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
Functions as two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs). Plays an important role in propagating cytokinin signal transduction.
Histidine-containing phosphotransfer domain (HPt) contains an active histidine that mediates the phosphotransfer.
Belongs to the helicase family. RecQ subfamily.
Belongs to the polyadenylate-binding protein type-1 family.
Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
Belongs to the ATP-dependent AMP-binding enzyme family.
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
Component of the endosomal sorting complex required for transport II (ESCRT-II).
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Belongs to the NRAMP (TC 2.A.55) family.
Belongs to the bacterial ribosomal protein bS6 family.
Belongs to the adaptor complexes medium subunit family.
The nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
Probably involved in the defense reaction of plants against pathogens.
Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
May be involved in the regulation of photosystem II.
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
Involved in storage lipid mobilization during the growth of higher plant seedling.
Belongs to the phytoene/squalene synthase family.
Belongs to the spermidine/spermine synthase family.
Belongs to the glutaredoxin family. CGFS subfamily.
Belongs to the glycosyl hydrolase 81 family.
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate: de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP.
In the C-terminal section; belongs to the thymidylate synthase family.
In the N-terminal section; belongs to the dihydrofolate reductase family.
Belongs to the glycosyltransferase 8 family.
Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
Belongs to the metallothionein superfamily. Type 15 family.
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Belongs to the V-ATPase E subunit family.
Acts as a negative regulator of abscisic acid (ABA) response.
Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.
Belongs to the adaptor complexes small subunit family.
Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates.
Belongs to the small GTPase superfamily. SAR1 family.
Involved in transport from the endoplasmic reticulum to the Golgi apparatus.
Belongs to the snRNP core protein family.
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
Belongs to the eukaryotic ribosomal protein eL22 family.
Belongs to the V-ATPase D subunit family.
Belongs to the iron/manganese superoxide dismutase family.
Confers resistance to late blight (Phytophthora infestans) races carrying the avirulence gene Avr1. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
Belongs to the enoyl-CoA hydratase/isomerase family.
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.
Belongs to the ATPase alpha/beta chains family.
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Belongs to the splicing factor SR family.
Belongs to the TALE/KNOX homeobox family.
Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP.
Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.
Component of the oligosaccharyltransferase (OST) complex.
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Belongs to the eukaryotic ribosomal protein eL31 family.
Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
Sphingolipid-delta-4-desaturase required for the biosynthesis of delta-4-unsaturated sphingolipids and derivatives.
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Belongs to the exonuclease superfamily. TREX family.
Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
Belongs to the actin-binding proteins ADF family.
Belongs to the prokaryotic/mitochondrial release factor family.
Belongs to the glycosyltransferase 92 family.
Belongs to the non-lysosomal glucosylceramidase family.
Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
Belongs to the two pore domain potassium channel (TC 1.A.1.7) family.
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
Belongs to the eukaryotic ribosomal protein eL18 family.
Belongs to the WD repeat DDB2/WDR76 family.
Possible role could be the docking of the LHC I antenna complex to the core complex.
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
Belongs to the universal ribosomal protein uL24 family.
Belongs to the eukaryotic initiation factor 4G family.
Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
Belongs to the triosephosphate isomerase family.
Belongs to the membrane magnesium transporter (TC 1.A.67) family.
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
The crystal structure with reduced Cu(1+) has also been determined.
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Ungrouped subfamily.
Belongs to the type IA topoisomerase family.
Associated with the oxygen-evolving complex of photosystem II.
Belongs to the calycin superfamily. Lipocalin family.
Belongs to the proteasome subunit S9 family.
Belongs to the glycosyltransferase 37 family.
May be involved in cell wall biosynthesis.
Belongs to the SOFL plant protein family.
Belongs to the alkaline ceramidase family.
Is involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Belongs to the aconitase/IPM isomerase family.
Belongs to the ZIP transporter (TC 2.A.5) family.
Belongs to the 2-oxoacid dehydrogenase family.
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane.
Belongs to the aromatic acid exporter (TC 2.A.85) family.
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
Contains one covalently linked phytochromobilin chromophore.
Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc. It also controls the expression of its own gene(s) in a negative feedback fashion.
Belongs to the acetyltransferase family. NAA40 subfamily.
Belongs to the auxin efflux carrier (TC 2.A.69.2) family.
Involved in cellular auxin homeostasis by regulating auxin metabolism. Regulates intracellular auxin accumulation at the endoplasmic reticulum and thus auxin availability for nuclear auxin signaling.
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Belongs to the glycosyl hydrolase 13 family.
Belongs to the anion exchanger (TC 2.A.31.3) family.
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
Belongs to the peptidase M10A family. Matrix metalloproteinases (MMPs) subfamily.
Can bind about 5 Ca(2+) ions per subunit.
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+).
Belongs to the deoxyhypusine hydroxylase family.
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Belongs to the eukaryotic ribosomal protein eL24 family.
Belongs to the OXA1/ALB3/YidC (TC 2.A.9.2) family.
Belongs to the universal ribosomal protein uL23 family.
Involved in the lipid remodeling steps of GPI-anchor maturation.
Responsible for the release of ribosomes from messenger RNA at the termination of chloroplastic protein biosynthesis.
Belongs to the ADP/ATP translocase tlc family.
Belongs to the methyltransferase superfamily. LCMT family.
Involved in brassinosteroid (BR) signaling.
Interacts with HSP90 in an ATP-dependent manner.
Belongs to the 11S seed storage protein (globulins) family.
Hexamer; each subunit is composed of an acidic and a basic chain derived from a single precursor and linked by a disulfide bond.
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Belongs to the universal ribosomal protein uL1 family.
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Belongs to the plant tobamovirus multiplication TOM1 protein family.
Belongs to the NUP186/NUP192/NUP205 family.
Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
The PAL motif is required for normal active site conformation.
Belongs to the class I fructose-bisphosphate aldolase family.
Belongs to the alpha-carbonic anhydrase family.
Belongs to the eukaryotic ribosomal protein eL21 family.
Acts as a component of a SCF E3 ubiquitin ligase complexes.
Component of the SCF-type E3 ligase complex.
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
Belongs to the eukaryotic initiation factor 4E family.
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
Belongs to the eukaryotic ribosomal protein eL36 family.
Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Belongs to the plant dirigent protein family.
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.
In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.
Belongs to the small GTPase superfamily. Arf family.
Belongs to the glycosyl hydrolase 18 family.
Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.
Belongs to the eukaryotic ribosomal protein eS4 family.
Belongs to the ATPase gamma chain family.
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
Belongs to the MICOS complex subunit Mic10 family.
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Belongs to the peptidase M28 family. M28B subfamily.
Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
Possesses 5'->3' exoribonuclease activity. Acts as an endogenous post-transcriptional gene silencing (PTGS) suppressor.
Belongs to the universal ribosomal protein uL30 family.
Belongs to the protein prenyltransferase subunit beta family.
Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
Belongs to the glycosyl hydrolase 37 family.
Acts as a calcium sensor. CBL proteins interact with CIPK serine-threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
Belongs to the calcineurin regulatory subunit family.
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Belongs to the peroxisomal targeting signal receptor family.
Belongs to the clathrin heavy chain family.
Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.
Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).
Belongs to the dienelactone hydrolase family.
Belongs to the glycosyl hydrolase 100 family.
Invertase that cleaves sucrose into glucose and fructose.
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Belongs to the dynein light chain family.
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
Belongs to the pyrroline-5-carboxylate reductase family.
Belongs to the histidine acid phosphatase family. VIP1 subfamily.
Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
Belongs to the universal ribosomal protein uS11 family.
Belongs to the bacterial ribosomal protein bL34 family.
Component of the ribosome quality control complex (RQC).
E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
Belongs to the proteasome subunit S5A family.
Belongs to the SLAC1 S-type anion channel family.
Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Belongs to the plant homeotic and developmental regulators ALOG protein family.
Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
Belongs to the eukaryotic ribosomal protein eL15 family.
Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
Belongs to the cysteine dioxygenase family.
Binds 1 heme c group covalently per subunit.
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Belongs to the IPP isomerase type 1 family.
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.
Belongs to the small GTPase superfamily. Ran family.
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
Belongs to the universal ribosomal protein uL4 family.
Belongs to the precorrin methyltransferase family.
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
Belongs to the replication factor A protein 2 family.
Belongs to the ABC transporter superfamily. ABCA family. CPR flippase (TC 3.A.1.211) subfamily.
Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
Belongs to the mannose-6-phosphate isomerase type 1 family.
Belongs to the trehalose phosphatase family.
Removes the phosphate from trehalose 6-phosphate to produce free trehalose. Trehalose accumulation in plant may improve abiotic stress tolerance.
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Belongs to the eukaryotic ribosomal protein eS10 family.
Belongs to the eukaryotic ribosomal protein eL14 family.
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
May be involved in the synthesis of minor phospholipids and in modulation of IP3-mediated signal transduction.
Requires a divalent cation for activity.
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
Belongs to the transketolase family. DXPS subfamily.
Belongs to the protein kinase superfamily. ADCK protein kinase family.
Belongs to the PC-esterase family. CASD1 subfamily.
Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
Belongs to the cyclin family. Cyclin AB subfamily.
Belongs to the succinate/malate CoA ligase alpha subunit family.
Heterodimer of an alpha and a beta subunit.
Heterooctamer of 4 alpha and 4 beta chains.
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
May be involved in modulation of pathogen defense and leaf cell death.
The C-terminus contains a calmodulin-binding domain, which binds calmodulin in a calcium-dependent fashion.
Belongs to the inositol phosphokinase (IPK) family.
Inositol phosphate kinase with a broad substrate specificity.
Belongs to the major facilitator superfamily. Sodium/anion cotransporter (TC 2.A.1.14) family.
Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding.
Belongs to the protein-tyrosine phosphatase family.
May be involved in nucleotide excision repair (By similarity). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP).
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
Belongs to the cyclin family. Cyclin U/P subfamily.
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Belongs to the cytochrome c family. PetJ subfamily.
Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.
Part of a SCF (SKP1-cullin-F-box) protein ligase complex.
Belongs to the PHD-associated homeobox family.
Belongs to the eukaryotic ribosomal protein eL30 family.
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
Belongs to the glycosyltransferase 22 family.
Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
Belongs to the BIG GRAIN 1 (BG1) plant protein family.
Involved in auxin transport. Regulator of the auxin signaling pathway.
May participate in a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Belongs to the glycosyltransferase 10 family.
Belongs to the DEAD box helicase family. DDX59 subfamily.
The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
The glycine cleavage system is composed of four proteins: P, T, L and H.
Belongs to the V-ATPase proteolipid subunit family.
Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Belongs to the glycosyltransferase 1 family.
Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate. Involved in the regulation of carbon partitioning in the leaves of plants. May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf. Plays a role for sucrose availability that is essential for plant growth and fiber elongation.
Belongs to the universal ribosomal protein uL11 family.
Belongs to the bacterial ribosomal protein bL17 family.
Belongs to the WIP C2H2-type zinc-finger protein family.
Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
Belongs to the ubiquitin family. SUMO subfamily.
Belongs to the eukaryotic ribosomal protein eL33 family.
Belongs to the eukaryotic ribosomal protein P1/P2 family.
P1 and P2 exist as dimers at the large ribosomal subunit.
Plays an important role in the elongation step of protein synthesis.
Belongs to the ParA family. MinD subfamily.
Belongs to the Mrp/NBP35 ATP-binding proteins family.
Involved in trafficking and recycling of synaptic vesicles.
Belongs to the universal ribosomal protein uS4 family.
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity). Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity). May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level.
Interacts with the 40S ribosomal subunit.
The SUI1 domain may be involved in RNA binding.
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.
Magnesium transporter that may mediate the influx of magnesium.
Belongs to the TDD superfamily. DTWD2 family.
Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
Belongs to the U1 small nuclear ribonucleoprotein C family.
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.
Belongs to the SSU72 phosphatase family.
Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.
Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.
Belongs to the protease inhibitor I13 (potato type I serine protease inhibitor) family.
Belongs to the RBOH (TC 5.B.1.3) family.
In the C-terminal section; belongs to the DHPS family.
Belongs to the glycosyltransferase 48 family.
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Belongs to the fatty acyl-CoA reductase family.
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).
Belongs to the glycosyl hydrolase 79 family.
Belongs to the folylpolyglutamate synthase family.
Component of the dolichol-phosphate mannose (DPM) synthase complex.
Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.
Belongs to the DNA photolyase class-1 family.
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/proton exchanger (CAX) subfamily.
Vacuolar cation/proton exchanger (CAX). Translocates Ca(2+) and other metal ions into vacuoles using the proton gradient formed by H(+)-ATPase and H(+)-pyrophosphatase.
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Endoplasmic reticulum-Golgi intermediate compartment membrane
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
Belongs to the glycosyl hydrolase 38 family.
Involved in nucleolar processing of pre-18S ribosomal RNA.
Belongs to the nicotianamine synthase (NAS)-like family.
Synthesizes nicotianamine, a polyamine which serves as a sensor for the physiological iron status within the plant, and/or might be involved in the transport of iron.
Belongs to the universal ribosomal protein uL29 family.
Belongs to the DDOST 48 kDa subunit family.
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
Belongs to the DNA repair enzymes AP/ExoA family.
Probably binds two magnesium or manganese ions per subunit.
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Belongs to the IAA-amido conjugating enzyme family.
Belongs to the Clp1 family. Clp1 subfamily.
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Belongs to the transferase hexapeptide repeat family.
Belongs to the universal ribosomal protein uS8 family.
Belongs to the universal ribosomal protein uL18 family.
Belongs to the universal ribosomal protein uL6 family.
Belongs to the bacterial ribosomal protein bTHX family.
Belongs to the poly(ADP-ribose) glycohydrolase family.
Belongs to the carotenoid oxygenase family.
Cytoprotective ribonuclease (RNase) required for resistance to abiotic stresses, acting as a positive regulator of mRNA decapping during stress.
Belongs to the radical SAM superfamily. Lipoyl synthase family.
Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.
Belongs to the glycosyltransferase 4 family. MraY subfamily.
Belongs to the eukaryotic ribosomal protein eS26 family.
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
Belongs to the casein kinase 2 subunit beta family.
Plays a complex role in regulating the basal catalytic activity of the alpha subunit.
Tetramer of two alpha and two beta subunits.
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
Belongs to the SurE nucleotidase family.
Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
Belongs to the acetyltransferase family. MAK3 subfamily.
Belongs to the ribose-phosphate pyrophosphokinase family.
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
Belongs to the WD repeat WDR12/YTM1 family.
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
Belongs to the enhancer of polycomb family.
Belongs to the acetolactate synthase small subunit family.
Sigma factors are initiation factors that promote the attachment of plastid-encoded RNA polymerase (PEP) to specific initiation sites and are then released.
Belongs to the eukaryotic ribosomal protein eS17 family.
Belongs to the eukaryotic ribosomal protein eS8 family.
Belongs to the universal ribosomal protein uL22 family.
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
This protein binds specifically to 23S rRNA.
Plays a role in vesicular protein sorting.
Belongs to the DNA photolyase class-2 family.
Belongs to the plant rapid alkalinization factor (RALF) family.
Belongs to the glycosyl hydrolase 43 family.
Belongs to the castor/pollux (TC 1.A.1.23) family.
Belongs to the eukaryotic ribosomal protein eL27 family.
Belongs to the replication factor A protein 1 family.
Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses.
Heterotrimer of RPA1, RPA2 and RPA3 (canonical replication protein A complex).
Belongs to the V-ATPase 116 kDa subunit family.
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
Belongs to the type IV zinc-finger family. Class A subfamily.
Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.
A pair of annexin repeats may form one binding site for calcium and phospholipid.
Belongs to the complex I NDUFA5 subunit family.
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Belongs to the copper/topaquinone oxidase family.
Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
Belongs to the RuBisCO small chain family.
Heterohexadecamer of 8 large and 8 small subunits.
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.
Belongs to the cytidylyltransferase family.
Belongs to the universal ribosomal protein uL15 family.
Belongs to the threonine synthase family.
Belongs to the JARID1 histone demethylase family.
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
Belongs to the geranylgeranyl reductase family. ChlP subfamily.
Belongs to the ribonucleoside diphosphate reductase small chain family.
Belongs to the aldehyde dehydrogenase family.
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Involved in the cell stress response.
Homodimer (By similarity). The glycine cleavage system is composed of four proteins: P, T, L and H.
The glycine cleavage system catalyzes the degradation of glycine.
Belongs to the complex I NDUFB10 subunit family.
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.
Belongs to the FPP/GGPP synthase family.
Belongs to the HMG-CoA reductase family.
Belongs to the proteasome subunit p55 family.
Belongs to the NADH dehydrogenase family.
Belongs to the eukaryotic ribosomal protein eS25 family.
Belongs to the Rieske iron-sulfur protein family.
Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and several low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
The Rieske protein is a high potential 2Fe-2S protein.
Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
Homooligomer. Interacts with ARC5 and FIS1B on peroxisomes.
Involved in peroxisomal proliferation. Promotes peroxisomal duplication, aggregation or elongation without fission.
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.
Belongs to the Mg-chelatase subunit H family.
Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
May serve as docking site to facilitate the association of other proteins to the plasma membrane.
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.
G proteins are composed of 3 units, alpha, beta and gamma.
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Component of several multiprotein Golgi SNARE complexes.
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane. Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation. TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation.
Allosterically activated by fructose 2,6-bisphosphate.
Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
Regulatory subunit of pyrophosphate--fructose 6-phosphate 1-phosphotransferase.
Tetramer of two alpha (regulatory) and two beta (catalytic) chains.
High-conductance voltage-dependent solute channel with a slight selectivity for cations transporting triosephosphates, dicarboxylic acids, ATP, inorganic phosphate (Pi), sugars, and positively or negatively charged amino acids.
Homooligomers form large rather nonselective pores in plastidial outer membranes.
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
May be involved in the transport of sterols.
Belongs to the WD repeat CDC20/Fizzy family.
Belongs to the glycosyltransferase 43 family.
Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls.
Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
Monomer. Associates with the 60S ribosomal subunit.
Belongs to the bacterial ribosomal protein bS20 family.
Belongs to the nucleosome assembly protein (NAP) family.
EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
Probably plays a role in anchoring the complex to other cellular components.
Belongs to the protease inhibitor I20 (potato type II proteinase inhibitor) family.
Belongs to the universal ribosomal protein uL2 family.
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
Belongs to the glycosyltransferase 34 family.
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Belongs to the glycosyltransferase 77 family.
Belongs to the bacterial ribosomal protein bL36 family.
Belongs to the peroxiredoxin family. Prx5 subfamily.
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
The active site is a redox-active disulfide bond.
Belongs to the GLUTAMINE DUMPER 1 (TC 9.B.60) family.
Belongs to the bacterial ribosomal protein bL9 family.
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
Carbamylation allows a single lysine to coordinate two divalent metal cations.
Accepts electrons from ETF and reduces ubiquinone.
Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
Belongs to the Nudix hydrolase family. CPSF5 subfamily.
Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing.
Homodimer. Component of the cleavage factor Im (CFIm) complex.
Belongs to the UPL family. TOM1/PTR1 subfamily.
Belongs to the endoribonuclease YbeY family.
Belongs to the HAD-like hydrolase superfamily. EYA family.
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Belongs to the proteasome subunit S1 family.
Component of the 19S regulatory particle (RP/PA700) base subcomplex of the 26S proteasome. The 26S proteasome is composed of a core protease (CP), known as the 20S proteasome, capped at one or both ends by the 19S regulatory particle (RP/PA700).
Belongs to the proteasome subunit p27 family.
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
In the N-terminal section; belongs to the DHBP synthase family.
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
Belongs to the SIS family. GutQ/KpsF subfamily.
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Belongs to the SMC family. SMC1 subfamily.
Belongs to the methyltransferase superfamily. NTM1 family.
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Belongs to the eukaryotic-type N-acetylglucosamine kinase family.
Belongs to the pseudouridine synthase TruB family.
During the catalytic reaction, a sulfide is transferred from Cys-225 to a reaction intermediate, generating a dehydroalanine residue.
Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
Belongs to the universal ribosomal protein uS3 family.
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
Probably involved in the biogenesis of the COX complex.
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
Belongs to the eukaryotic ribosomal protein eL43 family.
Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
Component of a multi-subunit COQ enzyme complex.
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
Belongs to the Mediator complex subunit 12 family.
Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
Belongs to the AP2/ERF transcription factor family. RAV subfamily.
Belongs to the DNA glycosylase family. DEMETER subfamily.
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
Belongs to the TFIIE alpha subunit family.
Belongs to the band 7/mec-2 family. Flotillin subfamily.
The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
Binds 1 thiamine pyrophosphate per subunit.
Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
Belongs to the RecA family. RAD51 subfamily.
Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Unwinds duplex DNA. Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over at later stages in meiosis. Probably is involved in the repair of meiotic double strand breaks (DBSs) and in homologous recombination.
Belongs to the mitochondrial Rho GTPase family.
Belongs to the universal ribosomal protein uS13 family.
Belongs to the chloroplast-specific ribosomal protein cS23 family.
Belongs to the Cold-regulated 413 protein family.
Probable UDP-L-arabinose mutase involved in the biosynthesis of cell wall non-cellulosic polysaccharides.
Divalent metal cations. Prefers magnesium or manganese.
Belongs to the PI3/PI4-kinase family. ATM subfamily.
Belongs to the proteasome subunit S14 family.
Belongs to the nucleotide-sugar transporter family. CMP-Sialate:CMP antiporter (TC 2.A.7.12) subfamily.
Belongs to the methyltransferase TRM13 family.
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.
Belongs to the glycosyl hydrolase 27 family.
Belongs to the plant CAR protein family.
Belongs to the helicase family. RecG subfamily.
Belongs to the eukaryotic ribosomal protein eL6 family.
Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
Belongs to the cytochrome c oxidase subunit 6A family.
Belongs to the NADPH--cytochrome P450 reductase family.
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
In the N-terminal section; belongs to the flavodoxin family.
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.
Belongs to the NFYB/HAP3 subunit family.
Belongs to the Mediator complex subunit 20 family.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
Belongs to the histone deacetylase family. HD Type 1 subfamily.
The GINS complex plays an essential role in the initiation of DNA replication.
Component of the 60S subunit of the ribosome.
In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
Component of nuclear RNase P and RNase MRP.
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Belongs to the glycosyltransferase 28 family.
Belongs to the uroporphyrinogen-III synthase family.
Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
Belongs to the MoaD family. MOCS2A subfamily.
C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
Required for vacuole biogenesis and vacuole enlargment in dividing and expanding cells. Involved in the docking or fusion of prevacuolar vesicles.
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
Belongs to the Mediator complex subunit 25 family.
Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.
Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
Belongs to the TRAPP small subunits family.
Part of the multisubunit transport protein particle (TRAPP) complex.
Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.
Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
Belongs to the BPG-independent phosphoglycerate mutase family.
Belongs to the MsrB Met sulfoxide reductase family.
Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins. Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation. MSRB family specifically reduces the MetSO R-enantiomer.
May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
Involved in protein precursor import into chloroplasts.
Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
Component of complex II composed of eight subunits in plants: four classical SDH subunits SDH1, SDH2, SDH3 and SDH4 (a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.), as well as four subunits unknown in mitochondria from bacteria and heterotrophic eukaryotes.
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
Belongs to the HD-ZIP homeobox family. Class III subfamily.
Belongs to the 6-phosphogluconate dehydrogenase family.
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
Belongs to the aldo/keto reductase family.
Belongs to the SLC35F solute transporter family.
Catalyzes the synthesis of activated sulfate.
Belongs to the acetyltransferase family. ArgA subfamily.
Belongs to the TFIIF alpha subunit family.
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.
Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
Heterodimer of an alpha and a beta chain.
Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.
Belongs to the methyltransferase superfamily. Fibrillarin family.
Belongs to the 5'-AMP-activated protein kinase beta subunit family.
Belongs to the ferredoxin--NADP reductase type 1 family.
Belongs to the PPP phosphatase family. BSU subfamily.
Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.
Belongs to the polysaccharide lyase 4 family.
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.
Belongs to the CSN7/EIF3M family. CSN7 subfamily.
Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
Belongs to the ATP-dependent DNA ligase family.
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Belongs to the CND2 (condensin subunit 2) family.
Belongs to the EF-1-beta/EF-1-delta family.
EF-1 is composed of 4 subunits: alpha, beta (1B-alpha=beta'), delta (1B-beta), and gamma (1B-gamma).
Belongs to the DNA glycosylase MPG family.
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
Belongs to the V-ATPase G subunit family.
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
Belongs to the WD repeat NOL10/ENP2 family.
Belongs to the peroxisomal membrane protein PXMP2/4 family.
Belongs to the eukaryotic release factor 1 family.
Belongs to the ribose 5-phosphate isomerase family.
Belongs to the DNA mismatch repair MutS family.
Component of the post-replicative DNA mismatch repair system (MMR).
Component of the 7-subunit TFIIH core complex.
In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
Belongs to the glutamine synthetase family.
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. TOC159 subfamily.
Belongs to the HD-ZIP homeobox family. Class II subfamily.
Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
Mediates the uptake of pyruvate into mitochondria.
Belongs to the MPDU1 (TC 2.A.43.3) family.
Belongs to the WD repeat G protein beta family.
Belongs to the CWC16 family. YJU2 subfamily.
Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.
Component of the 7-subunit TFIIH core complex composed of XPB, XPD, TFB1/GTF2H1, GTF2H2/P44, TFB4/GTF2H3, TFB2/GTF2H4 and TFB5/GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CYCH1/cyclin H1, CDKD and MAT1/At4g30820 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
Converts proline to delta-1-pyrroline-5-carboxylate.
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
Belongs to the CND3 (condensin subunit 3) family.
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
Belongs to the eukaryotic AdoMetDC family.
Binds 1 pyruvoyl group covalently per subunit.
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
Belongs to the bacterial ribosomal protein bL20 family.
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
Belongs to the GST superfamily. Phi family.
Belongs to the Mediator complex subunit 21 family.
Belongs to the alpha-ketoglutarate dehydrogenase family.
Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
May be involved in iron transport and iron homeostasis.
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Belongs to the eukaryotic NMN adenylyltransferase family.
Belongs to the retinoblastoma protein (RB) family.
Belongs to the peptidase M24 family. SPT16 subfamily.
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
Belongs to the RNA polymerase beta chain family.
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
Belongs to the universal ribosomal protein uL3 family.
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (Probable) (PubMed:31276744). Involved in the catabolism of quinolinic acid (QA).
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
Belongs to the mitochondrion-specific ribosomal protein mS29 family.
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
Belongs to the eukaryotic ribosomal protein eL42 family.
Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.
Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
Belongs to the transaldolase family. Type 1 subfamily.
Belongs to the glycosyl hydrolase 35 family.
Belongs to the DEAD box helicase family. DEAH subfamily.
Belongs to the activator 1 small subunits family.
Heterotetramer of subunits RFC2, RFC3, RFC4 and RFC5 that can form a complex with RFC1.
Belongs to the Mediator complex subunit 4 family.
Belongs to the WD repeat peroxin-7 family.
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
Belongs to the carotenoid/retinoid oxidoreductase family.
Converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene with a concomitant isomerization of two neighboring double bonds at the C9 and C9' positions from trans to cis.
Belongs to the plant DMP1 protein family.
Belongs to the GTP-binding SRP family. SRP54 subfamily.
Belongs to the proteasome subunit S11 family.
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.
Belongs to the succinate/malate CoA ligase beta subunit family.
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
Belongs to the DPH1/DPH2 family. DPH1 subfamily.
Belongs to the ERCC1/RAD10/SWI10 family.
GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
Belongs to the cystatin family. Phytocystatin subfamily.
Belongs to the Integrator subunit 3 family.
Belongs to the Mediator complex subunit 17 family.
Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
Belongs to the eukaryotic/archaeal PrmC-related family.
Belongs to the bacterial ribosomal protein bL19 family.
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
Belongs to the eukaryotic ribosomal protein eS19 family.
Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.
In the C-terminal section; belongs to the NAD synthetase family.
Belongs to the sirtuin family. Class II subfamily.
NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.
Belongs to the methylthiotransferase family. MiaB subfamily.
Belongs to the eukaryotic ribosomal protein eL8 family.
Common component of the spliceosome and rRNA processing machinery.
Belongs to the eukaryotic ribosomal protein eL20 family.
Belongs to the bacterial ribosomal protein bL32 family.
Belongs to the STXBP/unc-18/SEC1 family.
Involved in the tethering of the SIN3 complex to core histone proteins.
Belongs to the universal ribosomal protein uL10 family.
Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.
Belongs to the type II topoisomerase GyrA/ParC subunit family.
Belongs to the tRNA pseudouridine synthase TruA family.
Belongs to the glycosyl hydrolases 36 family.
Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.
Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
Belongs to the glycosyl hydrolase 20 family.
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Belongs to the bacterial ribosomal protein bL35 family.
Involved in ribosomal large subunit assembly.
Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
Belongs to the CRT-like transporter family.
Belongs to the inositol monophosphatase superfamily.
Component of a prohibitin multimeric complex in mitochondrial membranes.
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
Belongs to the adenylate kinase family. AK6 subfamily.
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity.
Belongs to the universal ribosomal protein uS7 family.
PSK-alpha is produced by endopeptidase digestion. PSK-beta is produced from PSK-alpha by exopeptidase digestion.
Promotes plant cell differentiation, organogenesis and somatic embryogenesis as well as cell proliferation.
Sulfation is important for activity and for the binding to a putative membrane receptor.
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Belongs to the RING-type zinc finger family. LOG2 subfamily.
Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.
Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.
Although plant and algal NBP35 proteins lack the characteristic CXXC motif in the C-terminus, thought to be required for Fe-S cluster binding, they can bind a [4Fe-4S] cluster in the C-terminus. Also, in this linage, no CFD1 partner protein homolog as found in other eukaryotes can be found.
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
Binds 3 [4Fe-4S] clusters per homodimer. Contains two stable clusters in the N-termini and one labile, bridging cluster between subunits of the homodimer.
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. Functions as Fe-S scaffold, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Essential for embryo development.
Homodimer and homotetramer. Predominantly homodimeric.
Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
Component of the pre-66S ribosomal particle.
Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
Belongs to the thioredoxin family. Plant CITRX-type subfamily.
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
Part of the nascent polypeptide-associated complex (NAC).
Belongs to the Mg-chelatase subunits D/I family.
Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.
Redox regulation; active in reducing conditions, inactive in oxidizing conditions.
The magnesium chelatase complex is a heterotrimer consisting of subunits CHLI, CHLD, AND CHLH.
Belongs to the eukaryotic ribosomal protein eS6 family.
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.