485916:DTOX RS20785
gene id: 485916:DTOX_RS20785
uniprot id: C8W005
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

485916:DTOX RS08060
gene id: 485916:DTOX_RS08060
uniprot id: C8VWF2
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

485916:DTOX RS17095
gene id: 485916:DTOX_RS17095
uniprot id: C8VVV7
names: Similarity
messages: Belongs to the UPRTase family.

485916:DTOX RS14995
gene id: 485916:DTOX_RS14995
uniprot id: C8W3Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

485916:DTOX RS19570
gene id: 485916:DTOX_RS19570
uniprot id: C8VYK5
names: Similarity
messages: Belongs to the UPF0175 family.

485916:DTOX RS13725
gene id: 485916:DTOX_RS13725
uniprot id: C8W1X3
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS10445
gene id: 485916:DTOX_RS10445
uniprot id: C8VZ41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

485916:DTOX RS01705
gene id: 485916:DTOX_RS01705
uniprot id: C8W431
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

485916:DTOX RS11355
gene id: 485916:DTOX_RS11355
uniprot id: C8W077
names: Similarity
messages: Belongs to the RemA family.

485916:DTOX RS13365
gene id: 485916:DTOX_RS13365
uniprot id: C8W1Q2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

485916:DTOX RS05390
gene id: 485916:DTOX_RS05390
uniprot id: C8W4D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

485916:DTOX RS18390
gene id: 485916:DTOX_RS18390
uniprot id: C8VXA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS06270
gene id: 485916:DTOX_RS06270
uniprot id: C8W686
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

485916:DTOX RS03665
gene id: 485916:DTOX_RS03665
uniprot id: C8W201
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

485916:DTOX RS12865
gene id: 485916:DTOX_RS12865
uniprot id: C8W123
names: Similarity
messages: Belongs to the HepT RNase toxin family.

485916:DTOX RS06030
gene id: 485916:DTOX_RS06030
uniprot id: C8W5F2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

485916:DTOX RS19375
gene id: 485916:DTOX_RS19375
uniprot id: C8VY59
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

485916:DTOX RS07050
gene id: 485916:DTOX_RS07050
uniprot id: C8VVK2
names: Similarity
messages: Belongs to the creatininase superfamily.

485916:DTOX RS09720
gene id: 485916:DTOX_RS09720
uniprot id: C8VYC8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS21645
gene id: 485916:DTOX_RS21645
uniprot id: C8W5J8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

485916:DTOX RS12995
gene id: 485916:DTOX_RS12995
uniprot id: C8W151
names: Similarity
messages: Belongs to the GSP E family.

485916:DTOX RS02840
gene id: 485916:DTOX_RS02840
uniprot id: C8W642
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

485916:DTOX RS18295
gene id: 485916:DTOX_RS18295
uniprot id: C8VX81
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

485916:DTOX RS15850
gene id: 485916:DTOX_RS15850
uniprot id: C8W5K4
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS19100
gene id: 485916:DTOX_RS19100
uniprot id: C8VY04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

485916:DTOX RS01765
gene id: 485916:DTOX_RS01765
uniprot id: C8W443
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS00995
gene id: 485916:DTOX_RS00995
uniprot id: C8W2Z6
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS01175
gene id: 485916:DTOX_RS01175
uniprot id: C8W3T5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

485916:DTOX RS02990
gene id: 485916:DTOX_RS02990
uniprot id: C8W673
names: Similarity
messages: Belongs to the UPF0047 family.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

485916:DTOX RS12735
gene id: 485916:DTOX_RS12735
uniprot id: C8W0Z9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

485916:DTOX RS12960
gene id: 485916:DTOX_RS12960
uniprot id: C8W142
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS19060
gene id: 485916:DTOX_RS19060
uniprot id: C8VXZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

485916:DTOX RS18260
gene id: 485916:DTOX_RS18260
uniprot id: C8VX74
names: Similarity
messages: Belongs to the glutamine synthetase family.

485916:DTOX RS01160
gene id: 485916:DTOX_RS01160
uniprot id: C8W3T2
names: Similarity
messages: Belongs to the UPF0251 family.

485916:DTOX RS00025
gene id: 485916:DTOX_RS00025
uniprot id: C8VVA2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

485916:DTOX RS15860
gene id: 485916:DTOX_RS15860
uniprot id: C8W5K6
names: Similarity
messages: Belongs to the asparagine synthetase family.

485916:DTOX RS11365
gene id: 485916:DTOX_RS11365
uniprot id: C8W079
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

485916:DTOX RS20675
gene id: 485916:DTOX_RS20675
uniprot id: C8VZK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

485916:DTOX RS18275
gene id: 485916:DTOX_RS18275
uniprot id: C8VX77
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

485916:DTOX RS00290
gene id: 485916:DTOX_RS00290
uniprot id: C8VVE9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS01570
gene id: 485916:DTOX_RS01570
uniprot id: C8W405
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

485916:DTOX RS13625
gene id: 485916:DTOX_RS13625
uniprot id: C8W1V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS05640
gene id: 485916:DTOX_RS05640
uniprot id: C8W574
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

485916:DTOX RS02805
gene id: 485916:DTOX_RS02805
uniprot id: C8W635
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

485916:DTOX RS02080
gene id: 485916:DTOX_RS02080
uniprot id: C8W501
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

485916:DTOX RS19370
gene id: 485916:DTOX_RS19370
uniprot id: C8VY58
names: Similarity
messages: Belongs to the glutamine synthetase family.

485916:DTOX RS11870
gene id: 485916:DTOX_RS11870
uniprot id: C8W0H8
names: Similarity
messages: Belongs to the ParB family.

485916:DTOX RS11380
gene id: 485916:DTOX_RS11380
uniprot id: C8W082
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

485916:DTOX RS03455
gene id: 485916:DTOX_RS03455
uniprot id: C8W1H9
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

485916:DTOX RS06730
gene id: 485916:DTOX_RS06730
uniprot id: C8W6H3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

485916:DTOX RS10665
gene id: 485916:DTOX_RS10665
uniprot id: C8VZL8
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS15445
gene id: 485916:DTOX_RS15445
uniprot id: C8W4P0
names: Similarity
messages: Belongs to the ribF family.

485916:DTOX RS04845
gene id: 485916:DTOX_RS04845
uniprot id: C8W3D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS04425
gene id: 485916:DTOX_RS04425
uniprot id: C8W346
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

485916:DTOX RS01615
gene id: 485916:DTOX_RS01615
uniprot id: C8W414
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

485916:DTOX RS03715
gene id: 485916:DTOX_RS03715
uniprot id: C8W211
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

485916:DTOX RS12985
gene id: 485916:DTOX_RS12985
uniprot id: C8W149
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

485916:DTOX RS00400
gene id: 485916:DTOX_RS00400
uniprot id: C8W1Y7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

485916:DTOX RS08315
gene id: 485916:DTOX_RS08315
uniprot id: C8VWY0
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

485916:DTOX RS17535
gene id: 485916:DTOX_RS17535
uniprot id: C8VW37
names: Caution
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS11510
gene id: 485916:DTOX_RS11510
uniprot id: C8W0A8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

485916:DTOX RS17730
gene id: 485916:DTOX_RS17730
uniprot id: C8VWJ7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

485916:DTOX RS09200
gene id: 485916:DTOX_RS09200
uniprot id: C8VXR3
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

485916:DTOX RS03270
gene id: 485916:DTOX_RS03270
uniprot id: C8W1D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

485916:DTOX RS14750
gene id: 485916:DTOX_RS14750
uniprot id: C8W3K6
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

485916:DTOX RS10825
gene id: 485916:DTOX_RS10825
uniprot id: C8VZP9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

485916:DTOX RS20960
gene id: 485916:DTOX_RS20960
uniprot id: C8W034
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS01455
gene id: 485916:DTOX_RS01455
uniprot id: C8W3Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

485916:DTOX RS11160
gene id: 485916:DTOX_RS11160
uniprot id: C8VZW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

485916:DTOX RS05875
gene id: 485916:DTOX_RS05875
uniprot id: C8W5C2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

485916:DTOX RS02930
gene id: 485916:DTOX_RS02930
uniprot id: C8W661
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

485916:DTOX RS20095
gene id: 485916:DTOX_RS20095
uniprot id: C8VZ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

485916:DTOX RS02065
gene id: 485916:DTOX_RS02065
uniprot id: C8W4Z8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

485916:DTOX RS20655
gene id: 485916:DTOX_RS20655
uniprot id: C8VZK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS14700
gene id: 485916:DTOX_RS14700
uniprot id: C8W3K0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

485916:DTOX RS06210
gene id: 485916:DTOX_RS06210
uniprot id: C8W5I1
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

485916:DTOX RS03675
gene id: 485916:DTOX_RS03675
uniprot id: C8W203
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

485916:DTOX RS07740
gene id: 485916:DTOX_RS07740
uniprot id: C8VW91
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

485916:DTOX RS16290
gene id: 485916:DTOX_RS16290
uniprot id: C8W5U0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS04370
gene id: 485916:DTOX_RS04370
uniprot id: C8W335
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS04755
gene id: 485916:DTOX_RS04755
uniprot id: C8W3A9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

485916:DTOX RS17005
gene id: 485916:DTOX_RS17005
uniprot id: C8VVU0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

485916:DTOX RS03385
gene id: 485916:DTOX_RS03385
uniprot id: C8W1G5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

485916:DTOX RS00505
gene id: 485916:DTOX_RS00505
uniprot id: C8W2Q7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

485916:DTOX RS04490
gene id: 485916:DTOX_RS04490
uniprot id: C8W358
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

485916:DTOX RS14935
gene id: 485916:DTOX_RS14935
uniprot id: C8W3P3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

485916:DTOX RS16940
gene id: 485916:DTOX_RS16940
uniprot id: C8W6V7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

485916:DTOX RS19045
gene id: 485916:DTOX_RS19045
uniprot id: C8VXZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

485916:DTOX RS14865
gene id: 485916:DTOX_RS14865
uniprot id: C8W3M9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS14880
gene id: 485916:DTOX_RS14880
uniprot id: C8W3N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

485916:DTOX RS03485
gene id: 485916:DTOX_RS03485
uniprot id: C8W1I5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

485916:DTOX RS14330
gene id: 485916:DTOX_RS14330
uniprot id: C8W2M9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

485916:DTOX RS10860
gene id: 485916:DTOX_RS10860
uniprot id: C8VZQ6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

485916:DTOX RS21100
gene id: 485916:DTOX_RS21100
uniprot id: C8W061
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

485916:DTOX RS06190
gene id: 485916:DTOX_RS06190
uniprot id: C8W5H7
names: Similarity
messages: Belongs to the HdrA family.

485916:DTOX RS07885
gene id: 485916:DTOX_RS07885
uniprot id: C8VWB9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS15415
gene id: 485916:DTOX_RS15415
uniprot id: C8W4N4
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

485916:DTOX RS03345
gene id: 485916:DTOX_RS03345
uniprot id: C8W1F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

485916:DTOX RS17640
gene id: 485916:DTOX_RS17640
uniprot id: C8VWH9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

485916:DTOX RS07645
gene id: 485916:DTOX_RS07645
uniprot id: C8VW76
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

485916:DTOX RS05025
gene id: 485916:DTOX_RS05025
uniprot id: C8W466
names: Similarity
messages: Belongs to the transpeptidase family.

485916:DTOX RS06230
gene id: 485916:DTOX_RS06230
uniprot id: C8W678
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

485916:DTOX RS23945
gene id: 485916:DTOX_RS23945
uniprot id: C8W6R6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

485916:DTOX RS14310
gene id: 485916:DTOX_RS14310
uniprot id: C8W2M5
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

485916:DTOX RS16475
gene id: 485916:DTOX_RS16475
uniprot id: C8W6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS04875
gene id: 485916:DTOX_RS04875
uniprot id: C8W3D6
names: Similarity
messages: Belongs to the P(II) protein family.

485916:DTOX RS02670
gene id: 485916:DTOX_RS02670
uniprot id: C8W609
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS03900
gene id: 485916:DTOX_RS03900
uniprot id: C8W248
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

485916:DTOX RS10110
gene id: 485916:DTOX_RS10110
uniprot id: C8VYX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

485916:DTOX RS02000
gene id: 485916:DTOX_RS02000
uniprot id: C8W4Z0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS15230
gene id: 485916:DTOX_RS15230
uniprot id: C8W4K1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS17585
gene id: 485916:DTOX_RS17585
uniprot id: C8VW45
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

485916:DTOX RS16025
gene id: 485916:DTOX_RS16025
uniprot id: C8W5N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

485916:DTOX RS10165
gene id: 485916:DTOX_RS10165
uniprot id: C8VYY2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

485916:DTOX RS19090
gene id: 485916:DTOX_RS19090
uniprot id: C8VY02
names: Similarity
messages: Belongs to the sigma-54 factor family.

485916:DTOX RS21005
gene id: 485916:DTOX_RS21005
uniprot id: C8W042
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

485916:DTOX RS14890
gene id: 485916:DTOX_RS14890
uniprot id: C8W3N4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

485916:DTOX RS07725
gene id: 485916:DTOX_RS07725
uniprot id: C8VW88
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

485916:DTOX RS04375
gene id: 485916:DTOX_RS04375
uniprot id: C8W336
names: Similarity
messages: Belongs to the TrpC family.

485916:DTOX RS05720
gene id: 485916:DTOX_RS05720
uniprot id: C8W590
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

485916:DTOX RS19140
gene id: 485916:DTOX_RS19140
uniprot id: C8VY12
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

485916:DTOX RS10410
gene id: 485916:DTOX_RS10410
uniprot id: C8VZ33
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

485916:DTOX RS08295
gene id: 485916:DTOX_RS08295
uniprot id: C8VWX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

485916:DTOX RS20215
gene id: 485916:DTOX_RS20215
uniprot id: C8VZB2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

485916:DTOX RS08925
gene id: 485916:DTOX_RS08925
uniprot id: C8VXL3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

485916:DTOX RS00115
gene id: 485916:DTOX_RS00115
uniprot id: C8VVB5
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS20170
gene id: 485916:DTOX_RS20170
uniprot id: C8VZA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

485916:DTOX RS19255
gene id: 485916:DTOX_RS19255
uniprot id: C8VY35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

485916:DTOX RS16680
gene id: 485916:DTOX_RS16680
uniprot id: C8W6R1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

485916:DTOX RS15645
gene id: 485916:DTOX_RS15645
uniprot id: C8W4S9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

485916:DTOX RS05785
gene id: 485916:DTOX_RS05785
uniprot id: C8W5A3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

485916:DTOX RS13000
gene id: 485916:DTOX_RS13000
uniprot id: C8W152
names: Similarity
messages: Belongs to the GSP E family.

485916:DTOX RS05825
gene id: 485916:DTOX_RS05825
uniprot id: C8W5B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

485916:DTOX RS20110
gene id: 485916:DTOX_RS20110
uniprot id: C8VZ91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

485916:DTOX RS13485
gene id: 485916:DTOX_RS13485
uniprot id: C8W1S7
names: Similarity
messages: Belongs to the TrpF family.

485916:DTOX RS18220
gene id: 485916:DTOX_RS18220
uniprot id: C8VWU8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS05550
gene id: 485916:DTOX_RS05550
uniprot id: C8W4H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

485916:DTOX RS08030
gene id: 485916:DTOX_RS08030
uniprot id: C8VWE6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

485916:DTOX RS05345
gene id: 485916:DTOX_RS05345
uniprot id: C8W4D1
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS21540
gene id: 485916:DTOX_RS21540
uniprot id: C8W0N2
names: Similarity
messages: Belongs to the peptidase A24 family.

485916:DTOX RS10345
gene id: 485916:DTOX_RS10345
uniprot id: C8VZ20
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

485916:DTOX RS19960
gene id: 485916:DTOX_RS19960
uniprot id: C8VYT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

485916:DTOX RS14120
gene id: 485916:DTOX_RS14120
uniprot id: C8W2I7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS05090
gene id: 485916:DTOX_RS05090
uniprot id: C8W480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

485916:DTOX RS20635
gene id: 485916:DTOX_RS20635
uniprot id: C8VZK0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

485916:DTOX RS16350
gene id: 485916:DTOX_RS16350
uniprot id: C8W5V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

485916:DTOX RS05230
gene id: 485916:DTOX_RS05230
uniprot id: C8W4A7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

485916:DTOX RS00285
gene id: 485916:DTOX_RS00285
uniprot id: C8VVE8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS13260
gene id: 485916:DTOX_RS13260
uniprot id: C8W1N2
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS15340
gene id: 485916:DTOX_RS15340
uniprot id: C8W4L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

485916:DTOX RS13245
gene id: 485916:DTOX_RS13245
uniprot id: C8W1M9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

485916:DTOX RS03255
gene id: 485916:DTOX_RS03255
uniprot id: C8W1D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

485916:DTOX RS20795
gene id: 485916:DTOX_RS20795
uniprot id: C8W007
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS01750
gene id: 485916:DTOX_RS01750
uniprot id: C8W440
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

485916:DTOX RS06685
gene id: 485916:DTOX_RS06685
uniprot id: C8W6G4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS01600
gene id: 485916:DTOX_RS01600
uniprot id: C8W411
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

485916:DTOX RS11170
gene id: 485916:DTOX_RS11170
uniprot id: C8VZW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS03375
gene id: 485916:DTOX_RS03375
uniprot id: C8W1G3
names: Similarity
messages: Belongs to the FlgD family.

485916:DTOX RS01465
gene id: 485916:DTOX_RS01465
uniprot id: C8W3Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

485916:DTOX RS11835
gene id: 485916:DTOX_RS11835
uniprot id: C8W0H2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

485916:DTOX RS19260
gene id: 485916:DTOX_RS19260
uniprot id: C8VY36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

485916:DTOX RS04670
gene id: 485916:DTOX_RS04670
uniprot id: C8W392
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS17060
gene id: 485916:DTOX_RS17060
uniprot id: C8VVV0
names: Similarity
messages: Belongs to the PspA/IM30 family.

485916:DTOX RS15920
gene id: 485916:DTOX_RS15920
uniprot id: C8W5L8
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

485916:DTOX RS14320
gene id: 485916:DTOX_RS14320
uniprot id: C8W2M7
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

485916:DTOX RS02835
gene id: 485916:DTOX_RS02835
uniprot id: C8W641
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

485916:DTOX RS19285
gene id: 485916:DTOX_RS19285
uniprot id: C8VY41
names: Similarity
messages: Belongs to the EamA transporter family.

485916:DTOX RS09850
gene id: 485916:DTOX_RS09850
uniprot id: C8VYF5
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

485916:DTOX RS11165
gene id: 485916:DTOX_RS11165
uniprot id: C8VZW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

485916:DTOX RS08010
gene id: 485916:DTOX_RS08010
uniprot id: C8VWE2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

485916:DTOX RS19905
gene id: 485916:DTOX_RS19905
uniprot id: C8VYS5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

485916:DTOX RS10195
gene id: 485916:DTOX_RS10195
uniprot id: C8VYY8
names: Similarity
messages: Belongs to the GerABKA family.

485916:DTOX RS01590
gene id: 485916:DTOX_RS01590
uniprot id: C8W409
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

485916:DTOX RS13125
gene id: 485916:DTOX_RS13125
uniprot id: C8W178
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

485916:DTOX RS00225
gene id: 485916:DTOX_RS00225
uniprot id: C8VVD6
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

485916:DTOX RS15580
gene id: 485916:DTOX_RS15580
uniprot id: C8W4R6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS01345
gene id: 485916:DTOX_RS01345
uniprot id: C8W3W4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

485916:DTOX RS15620
gene id: 485916:DTOX_RS15620
uniprot id: C8W4S4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

485916:DTOX RS15540
gene id: 485916:DTOX_RS15540
uniprot id: C8W4Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

485916:DTOX RS03170
gene id: 485916:DTOX_RS03170
uniprot id: C8W1A3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

485916:DTOX RS19080
gene id: 485916:DTOX_RS19080
uniprot id: C8VY00
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

485916:DTOX RS03775
gene id: 485916:DTOX_RS03775
uniprot id: C8W223
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

485916:DTOX RS20165
gene id: 485916:DTOX_RS20165
uniprot id: C8VZA2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

485916:DTOX RS11325
gene id: 485916:DTOX_RS11325
uniprot id: C8W071
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

485916:DTOX RS02785
gene id: 485916:DTOX_RS02785
uniprot id: C8W631
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

485916:DTOX RS04610
gene id: 485916:DTOX_RS04610
uniprot id: C8W380
names: Similarity
messages: Belongs to the threonine synthase family.

485916:DTOX RS11675
gene id: 485916:DTOX_RS11675
uniprot id: C8W0E1
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS15240
gene id: 485916:DTOX_RS15240
uniprot id: C8W4K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS20630
gene id: 485916:DTOX_RS20630
uniprot id: C8VZJ9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

485916:DTOX RS04905
gene id: 485916:DTOX_RS04905
uniprot id: C8W3E2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

485916:DTOX RS03420
gene id: 485916:DTOX_RS03420
uniprot id: C8W1H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

485916:DTOX RS03275
gene id: 485916:DTOX_RS03275
uniprot id: C8W1E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

485916:DTOX RS20020
gene id: 485916:DTOX_RS20020
uniprot id: C8VYU7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

485916:DTOX RS05800
gene id: 485916:DTOX_RS05800
uniprot id: C8W5A6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

485916:DTOX RS19095
gene id: 485916:DTOX_RS19095
uniprot id: C8VY03
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

485916:DTOX RS13645
gene id: 485916:DTOX_RS13645
uniprot id: C8W1V7
names: Similarity
messages: Belongs to the DtxR/MntR family.

485916:DTOX RS02530
gene id: 485916:DTOX_RS02530
uniprot id: C8W5Y0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

485916:DTOX RS05635
gene id: 485916:DTOX_RS05635
uniprot id: C8W573
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

485916:DTOX RS05210
gene id: 485916:DTOX_RS05210
uniprot id: C8W4A3
names: Similarity
messages: Belongs to the YggT family.

485916:DTOX RS05680
gene id: 485916:DTOX_RS05680
uniprot id: C8W582
names: Similarity
messages: Belongs to the fabD family.

485916:DTOX RS05685
gene id: 485916:DTOX_RS05685
uniprot id: C8W583
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

485916:DTOX RS12080
gene id: 485916:DTOX_RS12080
uniprot id: C8W0M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

485916:DTOX RS06760
gene id: 485916:DTOX_RS06760
uniprot id: C8W6H7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

485916:DTOX RS00875
gene id: 485916:DTOX_RS00875
uniprot id: C8W2X2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

485916:DTOX RS05850
gene id: 485916:DTOX_RS05850
uniprot id: C8W5B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

485916:DTOX RS05130
gene id: 485916:DTOX_RS05130
uniprot id: C8W488
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

485916:DTOX RS13205
gene id: 485916:DTOX_RS13205
uniprot id: C8W1L9
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

485916:DTOX RS21280
gene id: 485916:DTOX_RS21280
uniprot id: C8W1I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

485916:DTOX RS01420
gene id: 485916:DTOX_RS01420
uniprot id: C8W3X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

485916:DTOX RS05165
gene id: 485916:DTOX_RS05165
uniprot id: C8W494
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

485916:DTOX RS16400
gene id: 485916:DTOX_RS16400
uniprot id: C8W6K5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

485916:DTOX RS15550
gene id: 485916:DTOX_RS15550
uniprot id: C8W4R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

485916:DTOX RS15005
gene id: 485916:DTOX_RS15005
uniprot id: C8W3Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

485916:DTOX RS19230
gene id: 485916:DTOX_RS19230
uniprot id: C8VY30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

485916:DTOX RS11865
gene id: 485916:DTOX_RS11865
uniprot id: C8W0H7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

485916:DTOX RS17185
gene id: 485916:DTOX_RS17185
uniprot id: C8VVX5
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

485916:DTOX RS07865
gene id: 485916:DTOX_RS07865
uniprot id: C8VWB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

485916:DTOX RS18125
gene id: 485916:DTOX_RS18125
uniprot id: C8VWS8
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS15795
gene id: 485916:DTOX_RS15795
uniprot id: C8W5J4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

485916:DTOX RS13580
gene id: 485916:DTOX_RS13580
uniprot id: C8W1U2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

485916:DTOX RS04965
gene id: 485916:DTOX_RS04965
uniprot id: C8W454
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS00450
gene id: 485916:DTOX_RS00450
uniprot id: C8W1Z7
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

485916:DTOX RS19225
gene id: 485916:DTOX_RS19225
uniprot id: C8VY29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

485916:DTOX RS11525
gene id: 485916:DTOX_RS11525
uniprot id: C8W0B1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

485916:DTOX RS18190
gene id: 485916:DTOX_RS18190
uniprot id: C8VWU1
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS10555
gene id: 485916:DTOX_RS10555
uniprot id: C8VZ65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

485916:DTOX RS03540
gene id: 485916:DTOX_RS03540
uniprot id: C8W1J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

485916:DTOX RS06005
gene id: 485916:DTOX_RS06005
uniprot id: C8W5E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

485916:DTOX RS05985
gene id: 485916:DTOX_RS05985
uniprot id: C8W5E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

485916:DTOX RS16170
gene id: 485916:DTOX_RS16170
uniprot id: C8W5R7
names: Similarity
messages: Belongs to the transpeptidase family.

485916:DTOX RS11495
gene id: 485916:DTOX_RS11495
uniprot id: C8W0A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

485916:DTOX RS20965
gene id: 485916:DTOX_RS20965
uniprot id: C8W035
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

485916:DTOX RS01135
gene id: 485916:DTOX_RS01135
uniprot id: C8W3S7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

485916:DTOX RS11210
gene id: 485916:DTOX_RS11210
uniprot id: C8VZX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

485916:DTOX RS13695
gene id: 485916:DTOX_RS13695
uniprot id: C8W1W7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS06585
gene id: 485916:DTOX_RS06585
uniprot id: C8W6E5
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

485916:DTOX RS01670
gene id: 485916:DTOX_RS01670
uniprot id: C8W425
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS04505
gene id: 485916:DTOX_RS04505
uniprot id: C8W361
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

485916:DTOX RS15350
gene id: 485916:DTOX_RS15350
uniprot id: C8W4M1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

485916:DTOX RS16155
gene id: 485916:DTOX_RS16155
uniprot id: C8W5R4
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

485916:DTOX RS21270
gene id: 485916:DTOX_RS21270
uniprot id: C8W1G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

485916:DTOX RS03690
gene id: 485916:DTOX_RS03690
uniprot id: C8W206
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

485916:DTOX RS18265
gene id: 485916:DTOX_RS18265
uniprot id: C8VX75
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS16065
gene id: 485916:DTOX_RS16065
uniprot id: C8W5P5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

485916:DTOX RS05760
gene id: 485916:DTOX_RS05760
uniprot id: C8W598
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

485916:DTOX RS03710
gene id: 485916:DTOX_RS03710
uniprot id: C8W210
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

485916:DTOX RS00560
gene id: 485916:DTOX_RS00560
uniprot id: C8W2R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

485916:DTOX RS20030
gene id: 485916:DTOX_RS20030
uniprot id: C8VYU9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

485916:DTOX RS00640
gene id: 485916:DTOX_RS00640
uniprot id: C8W2T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

485916:DTOX RS16270
gene id: 485916:DTOX_RS16270
uniprot id: C8W5T6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

485916:DTOX RS04460
gene id: 485916:DTOX_RS04460
uniprot id: C8W352
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

485916:DTOX RS18380
gene id: 485916:DTOX_RS18380
uniprot id: C8VX98
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS20670
gene id: 485916:DTOX_RS20670
uniprot id: C8VZK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

485916:DTOX RS15480
gene id: 485916:DTOX_RS15480
uniprot id: C8W4P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

485916:DTOX RS15370
gene id: 485916:DTOX_RS15370
uniprot id: C8W4M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

485916:DTOX RS17520
gene id: 485916:DTOX_RS17520
uniprot id: C8VW34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

485916:DTOX RS07590
gene id: 485916:DTOX_RS07590
uniprot id: C8VW64
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS05110
gene id: 485916:DTOX_RS05110
uniprot id: C8W484
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

485916:DTOX RS05915
gene id: 485916:DTOX_RS05915
uniprot id: C8W5D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

485916:DTOX RS06725
gene id: 485916:DTOX_RS06725
uniprot id: C8W6H2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

485916:DTOX RS10690
gene id: 485916:DTOX_RS10690
uniprot id: C8VZM3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS05205
gene id: 485916:DTOX_RS05205
uniprot id: C8W4A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

485916:DTOX RS01910
gene id: 485916:DTOX_RS01910
uniprot id: C8W4X3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

485916:DTOX RS06535
gene id: 485916:DTOX_RS06535
uniprot id: C8W6D5
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

485916:DTOX RS05200
gene id: 485916:DTOX_RS05200
uniprot id: C8W4A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

485916:DTOX RS15460
gene id: 485916:DTOX_RS15460
uniprot id: C8W4P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

485916:DTOX RS19180
gene id: 485916:DTOX_RS19180
uniprot id: C8VY20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

485916:DTOX RS03355
gene id: 485916:DTOX_RS03355
uniprot id: C8W1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

485916:DTOX RS06490
gene id: 485916:DTOX_RS06490
uniprot id: C8W6C6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

485916:DTOX RS08680
gene id: 485916:DTOX_RS08680
uniprot id: C8VX49
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

485916:DTOX RS18240
gene id: 485916:DTOX_RS18240
uniprot id: C8VX70
names: Similarity
messages: Belongs to the glutamine synthetase family.

485916:DTOX RS05925
gene id: 485916:DTOX_RS05925
uniprot id: C8W5D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

485916:DTOX RS06690
gene id: 485916:DTOX_RS06690
uniprot id: C8W6G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

485916:DTOX RS04975
gene id: 485916:DTOX_RS04975
uniprot id: C8W456
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

485916:DTOX RS03410
gene id: 485916:DTOX_RS03410
uniprot id: C8W1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

485916:DTOX RS18115
gene id: 485916:DTOX_RS18115
uniprot id: C8VWS6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

485916:DTOX RS00300
gene id: 485916:DTOX_RS00300
uniprot id: C8VVF1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

485916:DTOX RS19365
gene id: 485916:DTOX_RS19365
uniprot id: C8VY57
names: Similarity
messages: Belongs to the polysaccharide synthase family.

485916:DTOX RS11050
gene id: 485916:DTOX_RS11050
uniprot id: C8VZU2
names: Similarity
messages: Belongs to the thioredoxin family.

485916:DTOX RS10275
gene id: 485916:DTOX_RS10275
uniprot id: C8VZ05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

485916:DTOX RS11335
gene id: 485916:DTOX_RS11335
uniprot id: C8W073
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

485916:DTOX RS03770
gene id: 485916:DTOX_RS03770
uniprot id: C8W222
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

485916:DTOX RS15250
gene id: 485916:DTOX_RS15250
uniprot id: C8W4K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

485916:DTOX RS02790
gene id: 485916:DTOX_RS02790
uniprot id: C8W632
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

485916:DTOX RS01810
gene id: 485916:DTOX_RS01810
uniprot id: C8W4V4
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS00395
gene id: 485916:DTOX_RS00395
uniprot id: C8W193
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

485916:DTOX RS15090
gene id: 485916:DTOX_RS15090
uniprot id: C8W4H6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

485916:DTOX RS06625
gene id: 485916:DTOX_RS06625
uniprot id: C8W6F2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

485916:DTOX RS16830
gene id: 485916:DTOX_RS16830
uniprot id: C8W6T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

485916:DTOX RS16990
gene id: 485916:DTOX_RS16990
uniprot id: C8VVT8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

485916:DTOX RS18285
gene id: 485916:DTOX_RS18285
uniprot id: C8VX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

485916:DTOX RS20895
gene id: 485916:DTOX_RS20895
uniprot id: C8W026
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS20270
gene id: 485916:DTOX_RS20270
uniprot id: C8VZC3
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

485916:DTOX RS08850
gene id: 485916:DTOX_RS08850
uniprot id: C8VXK5
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS20390
gene id: 485916:DTOX_RS20390
uniprot id: C8VZE8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

485916:DTOX RS21085
gene id: 485916:DTOX_RS21085
uniprot id: C8W058
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

485916:DTOX RS01320
gene id: 485916:DTOX_RS01320
uniprot id: C8W3V9
names: Similarity
messages: Belongs to the ycf81 family.

485916:DTOX RS02475
gene id: 485916:DTOX_RS02475
uniprot id: C8W5X0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

485916:DTOX RS05695
gene id: 485916:DTOX_RS05695
uniprot id: C8W585
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

485916:DTOX RS04925
gene id: 485916:DTOX_RS04925
uniprot id: C8W445
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

485916:DTOX RS03545
gene id: 485916:DTOX_RS03545
uniprot id: C8W1J7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

485916:DTOX RS20140
gene id: 485916:DTOX_RS20140
uniprot id: C8VZ97
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

485916:DTOX RS05865
gene id: 485916:DTOX_RS05865
uniprot id: C8W5C0
names: Similarity
messages: Belongs to the UPF0102 family.

485916:DTOX RS14980
gene id: 485916:DTOX_RS14980
uniprot id: C8W3Q3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

485916:DTOX RS08235
gene id: 485916:DTOX_RS08235
uniprot id: C8VWW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

485916:DTOX RS20665
gene id: 485916:DTOX_RS20665
uniprot id: C8VZK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

485916:DTOX RS21090
gene id: 485916:DTOX_RS21090
uniprot id: C8W059
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

485916:DTOX RS11275
gene id: 485916:DTOX_RS11275
uniprot id: C8VZY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

485916:DTOX RS06340
gene id: 485916:DTOX_RS06340
uniprot id: C8W6A0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

485916:DTOX RS19675
gene id: 485916:DTOX_RS19675
uniprot id: C8VYM9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

485916:DTOX RS08325
gene id: 485916:DTOX_RS08325
uniprot id: C8VWY2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

485916:DTOX RS14530
gene id: 485916:DTOX_RS14530
uniprot id: C8W3G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

485916:DTOX RS02900
gene id: 485916:DTOX_RS02900
uniprot id: C8W654
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS05220
gene id: 485916:DTOX_RS05220
uniprot id: C8W4A5
names: Subcellular Location Annotation
messages: Cytoplasm

485916:DTOX RS15405
gene id: 485916:DTOX_RS15405
uniprot id: C8W4N2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

485916:DTOX RS04380
gene id: 485916:DTOX_RS04380
uniprot id: C8W337
names: Similarity
messages: Belongs to the TrpF family.

485916:DTOX RS10545
gene id: 485916:DTOX_RS10545
uniprot id: C8VZ61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS05335
gene id: 485916:DTOX_RS05335
uniprot id: C8W4C9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

485916:DTOX RS19265
gene id: 485916:DTOX_RS19265
uniprot id: C8VY37
names: Subcellular Location Annotation
messages: Cytoplasm

485916:DTOX RS07540
gene id: 485916:DTOX_RS07540
uniprot id: C8VW53
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

485916:DTOX RS05625
gene id: 485916:DTOX_RS05625
uniprot id: C8W571
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

485916:DTOX RS17645
gene id: 485916:DTOX_RS17645
uniprot id: C8VWI0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS14675
gene id: 485916:DTOX_RS14675
uniprot id: C8W3J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

485916:DTOX RS14535
gene id: 485916:DTOX_RS14535
uniprot id: C8W3G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

485916:DTOX RS11725
gene id: 485916:DTOX_RS11725
uniprot id: C8W0F1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

485916:DTOX RS19160
gene id: 485916:DTOX_RS19160
uniprot id: C8VY16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

485916:DTOX RS01445
gene id: 485916:DTOX_RS01445
uniprot id: C8W3Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

485916:DTOX RS06240
gene id: 485916:DTOX_RS06240
uniprot id: C8W680
names: Similarity
messages: Belongs to the UPF0145 family.

485916:DTOX RS05030
gene id: 485916:DTOX_RS05030
uniprot id: C8W468
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS16150
gene id: 485916:DTOX_RS16150
uniprot id: C8W5R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

485916:DTOX RS03720
gene id: 485916:DTOX_RS03720
uniprot id: C8W212
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

485916:DTOX RS11480
gene id: 485916:DTOX_RS11480
uniprot id: C8W0A1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS03330
gene id: 485916:DTOX_RS03330
uniprot id: C8W1F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

485916:DTOX RS13430
gene id: 485916:DTOX_RS13430
uniprot id: C8W1R8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS15525
gene id: 485916:DTOX_RS15525
uniprot id: C8W4Q6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS14335
gene id: 485916:DTOX_RS14335
uniprot id: C8W2N0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS19720
gene id: 485916:DTOX_RS19720
uniprot id: C8VYN9
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

485916:DTOX RS17380
gene id: 485916:DTOX_RS17380
uniprot id: C8VW01
names: Similarity
messages: Belongs to the HdrA family.

485916:DTOX RS11080
gene id: 485916:DTOX_RS11080
uniprot id: C8VZU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

485916:DTOX RS04725
gene id: 485916:DTOX_RS04725
uniprot id: C8W3A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS04430
gene id: 485916:DTOX_RS04430
uniprot id: C8W347
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

485916:DTOX RS04700
gene id: 485916:DTOX_RS04700
uniprot id: C8W398
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS11755
gene id: 485916:DTOX_RS11755
uniprot id: C8W0F7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS10660
gene id: 485916:DTOX_RS10660
uniprot id: C8VZL7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

485916:DTOX RS18170
gene id: 485916:DTOX_RS18170
uniprot id: C8VWT7
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

485916:DTOX RS02950
gene id: 485916:DTOX_RS02950
uniprot id: C8W665
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

485916:DTOX RS08385
gene id: 485916:DTOX_RS08385
uniprot id: C8VWZ5
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

485916:DTOX RS05300
gene id: 485916:DTOX_RS05300
uniprot id: C8W4C2
names: Similarity
messages: Belongs to the manganese catalase family.

485916:DTOX RS21035
gene id: 485916:DTOX_RS21035
uniprot id: C8W048
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

485916:DTOX RS06695
gene id: 485916:DTOX_RS06695
uniprot id: C8W6G6
names: Similarity
messages: Belongs to the HdrA family.

485916:DTOX RS06070
gene id: 485916:DTOX_RS06070
uniprot id: C8W5G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

485916:DTOX RS02980
gene id: 485916:DTOX_RS02980
uniprot id: C8W671
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

485916:DTOX RS02220
gene id: 485916:DTOX_RS02220
uniprot id: C8W524
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS13680
gene id: 485916:DTOX_RS13680
uniprot id: C8W1W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

485916:DTOX RS12595
gene id: 485916:DTOX_RS12595
uniprot id: C8W0X0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

485916:DTOX RS06675
gene id: 485916:DTOX_RS06675
uniprot id: C8W6G2
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

485916:DTOX RS00645
gene id: 485916:DTOX_RS00645
uniprot id: C8W2T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

485916:DTOX RS07930
gene id: 485916:DTOX_RS07930
uniprot id: C8VWC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

485916:DTOX RS09180
gene id: 485916:DTOX_RS09180
uniprot id: C8VXQ9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS01305
gene id: 485916:DTOX_RS01305
uniprot id: C8W3V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

485916:DTOX RS15070
gene id: 485916:DTOX_RS15070
uniprot id: C8W3S1
names: Similarity
messages: Belongs to the CinA family.

485916:DTOX RS08045
gene id: 485916:DTOX_RS08045
uniprot id: C8VWE9
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

485916:DTOX RS06255
gene id: 485916:DTOX_RS06255
uniprot id: C8W683
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

485916:DTOX RS03740
gene id: 485916:DTOX_RS03740
uniprot id: C8W216
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS03780
gene id: 485916:DTOX_RS03780
uniprot id: C8W224
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS13185
gene id: 485916:DTOX_RS13185
uniprot id: C8W190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS11560
gene id: 485916:DTOX_RS11560
uniprot id: C8W0B8
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

485916:DTOX RS05400
gene id: 485916:DTOX_RS05400
uniprot id: C8W4E1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

485916:DTOX RS04710
gene id: 485916:DTOX_RS04710
uniprot id: C8W3A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

485916:DTOX RS17460
gene id: 485916:DTOX_RS17460
uniprot id: C8VW22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

485916:DTOX RS17665
gene id: 485916:DTOX_RS17665
uniprot id: C8VWI4
names: Similarity
messages: Belongs to the peptidase M29 family.

485916:DTOX RS15640
gene id: 485916:DTOX_RS15640
uniprot id: C8W4S8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

485916:DTOX RS04730
gene id: 485916:DTOX_RS04730
uniprot id: C8W3A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

485916:DTOX RS16805
gene id: 485916:DTOX_RS16805
uniprot id: C8W6T0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

485916:DTOX RS18360
gene id: 485916:DTOX_RS18360
uniprot id: C8VX94
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS06060
gene id: 485916:DTOX_RS06060
uniprot id: C8W5F8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

485916:DTOX RS20735
gene id: 485916:DTOX_RS20735
uniprot id: C8VZZ8
names: Similarity
messages: Belongs to the serpin family.

485916:DTOX RS20260
gene id: 485916:DTOX_RS20260
uniprot id: C8VZC1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS11215
gene id: 485916:DTOX_RS11215
uniprot id: C8VZX5
names: Similarity
messages: Belongs to the RecJ family.

485916:DTOX RS10170
gene id: 485916:DTOX_RS10170
uniprot id: C8VYY3
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

485916:DTOX RS03480
gene id: 485916:DTOX_RS03480
uniprot id: C8W1I4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS01645
gene id: 485916:DTOX_RS01645
uniprot id: C8W420
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

485916:DTOX RS20975
gene id: 485916:DTOX_RS20975
uniprot id: C8W037
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

485916:DTOX RS06275
gene id: 485916:DTOX_RS06275
uniprot id: C8W687
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

485916:DTOX RS06235
gene id: 485916:DTOX_RS06235
uniprot id: C8W679
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

485916:DTOX RS11015
gene id: 485916:DTOX_RS11015
uniprot id: C8VZT5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

485916:DTOX RS03295
gene id: 485916:DTOX_RS03295
uniprot id: C8W1E4
names: Similarity
messages: Belongs to the FlgM family.

485916:DTOX RS01635
gene id: 485916:DTOX_RS01635
uniprot id: C8W418
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS19830
gene id: 485916:DTOX_RS19830
uniprot id: C8VYR1
names: Similarity
messages: Belongs to the UDPGP type 2 family.

485916:DTOX RS03905
gene id: 485916:DTOX_RS03905
uniprot id: C8W249
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

485916:DTOX RS11070
gene id: 485916:DTOX_RS11070
uniprot id: C8VZU6
names: Similarity
messages: Belongs to the transpeptidase family.

485916:DTOX RS12465
gene id: 485916:DTOX_RS12465
uniprot id: C8W0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

485916:DTOX RS21265
gene id: 485916:DTOX_RS21265
uniprot id: C8W1G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS14670
gene id: 485916:DTOX_RS14670
uniprot id: C8W3J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

485916:DTOX RS09600
gene id: 485916:DTOX_RS09600
uniprot id: C8VYB1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

485916:DTOX RS05600
gene id: 485916:DTOX_RS05600
uniprot id: C8W566
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

485916:DTOX RS19970
gene id: 485916:DTOX_RS19970
uniprot id: C8VYT8
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

485916:DTOX RS18795
gene id: 485916:DTOX_RS18795
uniprot id: C8VXH6
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

485916:DTOX RS02920
gene id: 485916:DTOX_RS02920
uniprot id: C8W659
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

485916:DTOX RS13970
gene id: 485916:DTOX_RS13970
uniprot id: C8W2F9
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

485916:DTOX RS19150
gene id: 485916:DTOX_RS19150
uniprot id: C8VY14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS05385
gene id: 485916:DTOX_RS05385
uniprot id: C8W4D8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

485916:DTOX RS08535
gene id: 485916:DTOX_RS08535
uniprot id: C8VX25
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS21015
gene id: 485916:DTOX_RS21015
uniprot id: C8W044
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

485916:DTOX RS02720
gene id: 485916:DTOX_RS02720
uniprot id: C8W619
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

485916:DTOX RS03680
gene id: 485916:DTOX_RS03680
uniprot id: C8W204
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

485916:DTOX RS21250
gene id: 485916:DTOX_RS21250
uniprot id: C8W1C3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

485916:DTOX RS11540
gene id: 485916:DTOX_RS11540
uniprot id: C8W0B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS14885
gene id: 485916:DTOX_RS14885
uniprot id: C8W3N3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

485916:DTOX RS19085
gene id: 485916:DTOX_RS19085
uniprot id: C8VY01
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

485916:DTOX RS03280
gene id: 485916:DTOX_RS03280
uniprot id: C8W1E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

485916:DTOX RS11345
gene id: 485916:DTOX_RS11345
uniprot id: C8W075
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

485916:DTOX RS21480
gene id: 485916:DTOX_RS21480
uniprot id: C8VYC1
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS03640
gene id: 485916:DTOX_RS03640
uniprot id: C8W1L5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

485916:DTOX RS14505
gene id: 485916:DTOX_RS14505
uniprot id: C8W3G2
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

485916:DTOX RS08875
gene id: 485916:DTOX_RS08875
uniprot id: C8VXL0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

485916:DTOX RS11515
gene id: 485916:DTOX_RS11515
uniprot id: C8W0A9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

485916:DTOX RS20750
gene id: 485916:DTOX_RS20750
uniprot id: C8W000
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

485916:DTOX RS03260
gene id: 485916:DTOX_RS03260
uniprot id: C8W1D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

485916:DTOX RS01735
gene id: 485916:DTOX_RS01735
uniprot id: C8W437
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

485916:DTOX RS05820
gene id: 485916:DTOX_RS05820
uniprot id: C8W5B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

485916:DTOX RS13455
gene id: 485916:DTOX_RS13455
uniprot id: C8W1S2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

485916:DTOX RS12990
gene id: 485916:DTOX_RS12990
uniprot id: C8W150
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

485916:DTOX RS04750
gene id: 485916:DTOX_RS04750
uniprot id: C8W3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

485916:DTOX RS08765
gene id: 485916:DTOX_RS08765
uniprot id: C8VX66
names: Similarity
messages: Belongs to the UPF0178 family.

485916:DTOX RS09865
gene id: 485916:DTOX_RS09865
uniprot id: C8VYF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

485916:DTOX RS14860
gene id: 485916:DTOX_RS14860
uniprot id: C8W3M8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

485916:DTOX RS13360
gene id: 485916:DTOX_RS13360
uniprot id: C8W1Q1
names: Similarity
messages: Belongs to the GSP E family.

485916:DTOX RS08300
gene id: 485916:DTOX_RS08300
uniprot id: C8VWX7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

485916:DTOX RS14685
gene id: 485916:DTOX_RS14685
uniprot id: C8W3J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Cytoplasm
messages: Gas vesicle
messages: Vesicle

485916:DTOX RS15890
gene id: 485916:DTOX_RS15890
uniprot id: C8W5L3
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS07670
gene id: 485916:DTOX_RS07670
uniprot id: C8VW79
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

485916:DTOX RS04960
gene id: 485916:DTOX_RS04960
uniprot id: C8W452
names: Similarity
messages: Belongs to the asparagine synthetase family.

485916:DTOX RS20150
gene id: 485916:DTOX_RS20150
uniprot id: C8VZ99
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

485916:DTOX RS11245
gene id: 485916:DTOX_RS11245
uniprot id: C8VZY2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

485916:DTOX RS13940
gene id: 485916:DTOX_RS13940
uniprot id: C8W2F3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

485916:DTOX RS05185
gene id: 485916:DTOX_RS05185
uniprot id: C8W498
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

485916:DTOX RS11700
gene id: 485916:DTOX_RS11700
uniprot id: C8W0E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

485916:DTOX RS15130
gene id: 485916:DTOX_RS15130
uniprot id: C8W4I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS16250
gene id: 485916:DTOX_RS16250
uniprot id: C8W5T2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

485916:DTOX RS09685
gene id: 485916:DTOX_RS09685
uniprot id: C8VYC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

485916:DTOX RS07820
gene id: 485916:DTOX_RS07820
uniprot id: C8VWA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

485916:DTOX RS05170
gene id: 485916:DTOX_RS05170
uniprot id: C8W495
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS20115
gene id: 485916:DTOX_RS20115
uniprot id: C8VZ92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

485916:DTOX RS07755
gene id: 485916:DTOX_RS07755
uniprot id: C8VW95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS02435
gene id: 485916:DTOX_RS02435
uniprot id: C8W5W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS08455
gene id: 485916:DTOX_RS08455
uniprot id: C8VX10
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

485916:DTOX RS18255
gene id: 485916:DTOX_RS18255
uniprot id: C8VX73
names: Similarity
messages: Belongs to the glutamate synthase family.

485916:DTOX RS15775
gene id: 485916:DTOX_RS15775
uniprot id: C8W5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

485916:DTOX RS14990
gene id: 485916:DTOX_RS14990
uniprot id: C8W3Q5
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

485916:DTOX RS16570
gene id: 485916:DTOX_RS16570
uniprot id: C8W6N7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

485916:DTOX RS16225
gene id: 485916:DTOX_RS16225
uniprot id: C8W5S8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

485916:DTOX RS00475
gene id: 485916:DTOX_RS00475
uniprot id: C8W2P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

485916:DTOX RS12880
gene id: 485916:DTOX_RS12880
uniprot id: C8W126
names: Similarity
messages: Belongs to the GbsR family.

485916:DTOX RS05665
gene id: 485916:DTOX_RS05665
uniprot id: C8W579
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

485916:DTOX RS16560
gene id: 485916:DTOX_RS16560
uniprot id: C8W6N5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

485916:DTOX RS07240
gene id: 485916:DTOX_RS07240
uniprot id: C8VVN3
names: Similarity
messages: Belongs to the peptidase A24 family.

485916:DTOX RS21025
gene id: 485916:DTOX_RS21025
uniprot id: C8W046
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

485916:DTOX RS06930
gene id: 485916:DTOX_RS06930
uniprot id: C8VVI4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

485916:DTOX RS18300
gene id: 485916:DTOX_RS18300
uniprot id: C8VX82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS19965
gene id: 485916:DTOX_RS19965
uniprot id: C8VYT7
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

485916:DTOX RS01230
gene id: 485916:DTOX_RS01230
uniprot id: C8W3U6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

485916:DTOX RS19185
gene id: 485916:DTOX_RS19185
uniprot id: C8VY21
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

485916:DTOX RS04655
gene id: 485916:DTOX_RS04655
uniprot id: C8W389
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS05615
gene id: 485916:DTOX_RS05615
uniprot id: C8W569
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

485916:DTOX RS02970
gene id: 485916:DTOX_RS02970
uniprot id: C8W669
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

485916:DTOX RS02640
gene id: 485916:DTOX_RS02640
uniprot id: C8W603
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS18325
gene id: 485916:DTOX_RS18325
uniprot id: C8VX87
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

485916:DTOX RS05070
gene id: 485916:DTOX_RS05070
uniprot id: C8W476
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS01525
gene id: 485916:DTOX_RS01525
uniprot id: C8W3Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

485916:DTOX RS10505
gene id: 485916:DTOX_RS10505
uniprot id: C8VZ53
names: Similarity
messages: Belongs to the class-I fumarase family.

485916:DTOX RS05710
gene id: 485916:DTOX_RS05710
uniprot id: C8W588
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

485916:DTOX RS04900
gene id: 485916:DTOX_RS04900
uniprot id: C8W3E1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

485916:DTOX RS11740
gene id: 485916:DTOX_RS11740
uniprot id: C8W0F4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

485916:DTOX RS17530
gene id: 485916:DTOX_RS17530
uniprot id: C8VW36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

485916:DTOX RS10020
gene id: 485916:DTOX_RS10020
uniprot id: C8VYI5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

485916:DTOX RS01725
gene id: 485916:DTOX_RS01725
uniprot id: C8W435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS11105
gene id: 485916:DTOX_RS11105
uniprot id: C8VZV3
names: Similarity
messages: Belongs to the UPF0297 family.

485916:DTOX RS05260
gene id: 485916:DTOX_RS05260
uniprot id: C8W4B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

485916:DTOX RS18695
gene id: 485916:DTOX_RS18695
uniprot id: C8VXG2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

485916:DTOX RS16160
gene id: 485916:DTOX_RS16160
uniprot id: C8W5R5
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

485916:DTOX RS05895
gene id: 485916:DTOX_RS05895
uniprot id: C8W5C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

485916:DTOX RS04020
gene id: 485916:DTOX_RS04020
uniprot id: C8W271
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

485916:DTOX RS09530
gene id: 485916:DTOX_RS09530
uniprot id: C8VY97
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

485916:DTOX RS00385
gene id: 485916:DTOX_RS00385
uniprot id: C8VVF4
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS12410
gene id: 485916:DTOX_RS12410
uniprot id: C8W0T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

485916:DTOX RS07730
gene id: 485916:DTOX_RS07730
uniprot id: C8VW89
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS05900
gene id: 485916:DTOX_RS05900
uniprot id: C8W5C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

485916:DTOX RS03925
gene id: 485916:DTOX_RS03925
uniprot id: C8W253
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

485916:DTOX RS03030
gene id: 485916:DTOX_RS03030
uniprot id: C8W0W7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS02660
gene id: 485916:DTOX_RS02660
uniprot id: C8W607
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

485916:DTOX RS04485
gene id: 485916:DTOX_RS04485
uniprot id: C8W357
names: Subcellular Location Annotation
messages: Cell membrane

485916:DTOX RS21565
gene id: 485916:DTOX_RS21565
uniprot id: C8W1P6
names: Similarity
messages: Belongs to the TrpF family.

485916:DTOX RS05095
gene id: 485916:DTOX_RS05095
uniprot id: C8W481
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

485916:DTOX RS15375
gene id: 485916:DTOX_RS15375
uniprot id: C8W4M6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

485916:DTOX RS19820
gene id: 485916:DTOX_RS19820
uniprot id: C8VYQ8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

485916:DTOX RS20120
gene id: 485916:DTOX_RS20120
uniprot id: C8VZ93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

485916:DTOX RS10895
gene id: 485916:DTOX_RS10895
uniprot id: C8VZR3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

485916:DTOX RS17705
gene id: 485916:DTOX_RS17705
uniprot id: C8VWJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

485916:DTOX RS21060
gene id: 485916:DTOX_RS21060
uniprot id: C8W053
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS02635
gene id: 485916:DTOX_RS02635
uniprot id: C8W602
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS06420
gene id: 485916:DTOX_RS06420
uniprot id: C8W6B3
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

485916:DTOX RS10610
gene id: 485916:DTOX_RS10610
uniprot id: C8VZ74
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

485916:DTOX RS01450
gene id: 485916:DTOX_RS01450
uniprot id: C8W3Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

485916:DTOX RS17690
gene id: 485916:DTOX_RS17690
uniprot id: C8VWI9
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

485916:DTOX RS18130
gene id: 485916:DTOX_RS18130
uniprot id: C8VWS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

485916:DTOX RS17550
gene id: 485916:DTOX_RS17550
uniprot id: C8VW40
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

485916:DTOX RS07140
gene id: 485916:DTOX_RS07140
uniprot id: C8VVL5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

485916:DTOX RS01205
gene id: 485916:DTOX_RS01205
uniprot id: C8W3U1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

485916:DTOX RS00085
gene id: 485916:DTOX_RS00085
uniprot id: C8VVB0
names: Similarity
messages: Belongs to the SecB family.

485916:DTOX RS19935
gene id: 485916:DTOX_RS19935
uniprot id: C8VYT1
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS07195
gene id: 485916:DTOX_RS07195
uniprot id: C8VVM4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

485916:DTOX RS14360
gene id: 485916:DTOX_RS14360
uniprot id: C8W2N5
names: Similarity
messages: Belongs to the peptidase C40 family.

485916:DTOX RS14825
gene id: 485916:DTOX_RS14825
uniprot id: C8W3M1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS01460
gene id: 485916:DTOX_RS01460
uniprot id: C8W3Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

485916:DTOX RS09860
gene id: 485916:DTOX_RS09860
uniprot id: C8VYF7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

485916:DTOX RS03100
gene id: 485916:DTOX_RS03100
uniprot id: C8W1A3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

485916:DTOX RS20890
gene id: 485916:DTOX_RS20890
uniprot id: C8W025
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

485916:DTOX RS03460
gene id: 485916:DTOX_RS03460
uniprot id: C8W1I0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

485916:DTOX RS02795
gene id: 485916:DTOX_RS02795
uniprot id: C8W633
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

485916:DTOX RS01665
gene id: 485916:DTOX_RS01665
uniprot id: C8W424
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

485916:DTOX RS14515
gene id: 485916:DTOX_RS14515
uniprot id: C8W3G4
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

485916:DTOX RS02995
gene id: 485916:DTOX_RS02995
uniprot id: C8W674
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

485916:DTOX RS11110
gene id: 485916:DTOX_RS11110
uniprot id: C8VZV4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

485916:DTOX RS05065
gene id: 485916:DTOX_RS05065
uniprot id: C8W475
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

485916:DTOX RS11270
gene id: 485916:DTOX_RS11270
uniprot id: C8VZY7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

485916:DTOX RS21375
gene id: 485916:DTOX_RS21375
uniprot id: C8VW69
names: Similarity
messages: Belongs to the universal stress protein A family.

485916:DTOX RS03555
gene id: 485916:DTOX_RS03555
uniprot id: C8W1J9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

485916:DTOX RS01800
gene id: 485916:DTOX_RS01800
uniprot id: C8W4V2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

485916:DTOX RS21385
gene id: 485916:DTOX_RS21385
uniprot id: C8VW83
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Membrane

485916:DTOX RS11200
gene id: 485916:DTOX_RS11200
uniprot id: C8VZX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

485916:DTOX RS08105
gene id: 485916:DTOX_RS08105
uniprot id: C8VWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

485916:DTOX RS15895
gene id: 485916:DTOX_RS15895
uniprot id: C8W5L4
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS16650
gene id: 485916:DTOX_RS16650
uniprot id: C8W6Q5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

485916:DTOX RS15135
gene id: 485916:DTOX_RS15135
uniprot id: C8W4I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS08070
gene id: 485916:DTOX_RS08070
uniprot id: C8VWF4
names: Subcellular Location Annotation
messages: Mitochondrion

485916:DTOX RS02580
gene id: 485916:DTOX_RS02580
uniprot id: C8W5Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

485916:DTOX RS15630
gene id: 485916:DTOX_RS15630
uniprot id: C8W4S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

485916:DTOX RS01795
gene id: 485916:DTOX_RS01795
uniprot id: C8W4V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS01720
gene id: 485916:DTOX_RS01720
uniprot id: C8W434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS09440
gene id: 485916:DTOX_RS09440
uniprot id: C8VY83
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

485916:DTOX RS10470
gene id: 485916:DTOX_RS10470
uniprot id: C8VZ46
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

485916:DTOX RS13980
gene id: 485916:DTOX_RS13980
uniprot id: C8W2G1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

485916:DTOX RS20575
gene id: 485916:DTOX_RS20575
uniprot id: C8VZI8
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS17020
gene id: 485916:DTOX_RS17020
uniprot id: C8VVU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

485916:DTOX RS16010
gene id: 485916:DTOX_RS16010
uniprot id: C8W5N4
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS00340
gene id: 485916:DTOX_RS00340
uniprot id: C8VVG2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

485916:DTOX RS08240
gene id: 485916:DTOX_RS08240
uniprot id: C8VWW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

485916:DTOX RS01955
gene id: 485916:DTOX_RS01955
uniprot id: C8W4Y1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS13115
gene id: 485916:DTOX_RS13115
uniprot id: C8W176
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

485916:DTOX RS19305
gene id: 485916:DTOX_RS19305
uniprot id: C8VY45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

485916:DTOX RS14580
gene id: 485916:DTOX_RS14580
uniprot id: C8W3H6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS00345
gene id: 485916:DTOX_RS00345
uniprot id: C8VVG3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS03930
gene id: 485916:DTOX_RS03930
uniprot id: C8W254
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

485916:DTOX RS01540
gene id: 485916:DTOX_RS01540
uniprot id: C8W3Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

485916:DTOX RS01510
gene id: 485916:DTOX_RS01510
uniprot id: C8W3Z3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

485916:DTOX RS00135
gene id: 485916:DTOX_RS00135
uniprot id: C8VVB9
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

485916:DTOX RS17915
gene id: 485916:DTOX_RS17915
uniprot id: C8VWN6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

485916:DTOX RS03950
gene id: 485916:DTOX_RS03950
uniprot id: C8W258
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS11565
gene id: 485916:DTOX_RS11565
uniprot id: C8W0B9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

485916:DTOX RS02875
gene id: 485916:DTOX_RS02875
uniprot id: C8W649
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

485916:DTOX RS10420
gene id: 485916:DTOX_RS10420
uniprot id: C8VZ36
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

485916:DTOX RS14850
gene id: 485916:DTOX_RS14850
uniprot id: C8W3M6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

485916:DTOX RS03830
gene id: 485916:DTOX_RS03830
uniprot id: C8W234
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS13775
gene id: 485916:DTOX_RS13775
uniprot id: C8W1Y3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

485916:DTOX RS02765
gene id: 485916:DTOX_RS02765
uniprot id: C8W627
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS15095
gene id: 485916:DTOX_RS15095
uniprot id: C8W4H7
names: Similarity
messages: Belongs to the UPF0234 family.

485916:DTOX RS11315
gene id: 485916:DTOX_RS11315
uniprot id: C8W069
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

485916:DTOX RS16285
gene id: 485916:DTOX_RS16285
uniprot id: C8W5T9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

485916:DTOX RS17190
gene id: 485916:DTOX_RS17190
uniprot id: C8VVX6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

485916:DTOX RS11095
gene id: 485916:DTOX_RS11095
uniprot id: C8VZV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

485916:DTOX RS18120
gene id: 485916:DTOX_RS18120
uniprot id: C8VWS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

485916:DTOX RS18420
gene id: 485916:DTOX_RS18420
uniprot id: C8VXA6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

485916:DTOX RS09605
gene id: 485916:DTOX_RS09605
uniprot id: C8VYB2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS16320
gene id: 485916:DTOX_RS16320
uniprot id: C8W5U6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

485916:DTOX RS02675
gene id: 485916:DTOX_RS02675
uniprot id: C8W610
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS01545
gene id: 485916:DTOX_RS01545
uniprot id: C8W400
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

485916:DTOX RS11350
gene id: 485916:DTOX_RS11350
uniprot id: C8W076
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

485916:DTOX RS01880
gene id: 485916:DTOX_RS01880
uniprot id: C8W4W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS16070
gene id: 485916:DTOX_RS16070
uniprot id: C8W5P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

485916:DTOX RS03655
gene id: 485916:DTOX_RS03655
uniprot id: C8W1Z9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

485916:DTOX RS19690
gene id: 485916:DTOX_RS19690
uniprot id: C8VYN2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

485916:DTOX RS04475
gene id: 485916:DTOX_RS04475
uniprot id: C8W355
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.

485916:DTOX RS17790
gene id: 485916:DTOX_RS17790
uniprot id: C8VWK7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

485916:DTOX RS10850
gene id: 485916:DTOX_RS10850
uniprot id: C8VZQ4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

485916:DTOX RS15060
gene id: 485916:DTOX_RS15060
uniprot id: C8W3R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

485916:DTOX RS01475
gene id: 485916:DTOX_RS01475
uniprot id: C8W3Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

485916:DTOX RS16960
gene id: 485916:DTOX_RS16960
uniprot id: C8W6W1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

485916:DTOX RS11745
gene id: 485916:DTOX_RS11745
uniprot id: C8W0F5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

485916:DTOX RS06520
gene id: 485916:DTOX_RS06520
uniprot id: C8W6D2
names: Similarity
messages: Belongs to the UPF0173 family.

485916:DTOX RS05890
gene id: 485916:DTOX_RS05890
uniprot id: C8W5C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

485916:DTOX RS01560
gene id: 485916:DTOX_RS01560
uniprot id: C8W403
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

485916:DTOX RS03430
gene id: 485916:DTOX_RS03430
uniprot id: C8W1H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

485916:DTOX RS02425
gene id: 485916:DTOX_RS02425
uniprot id: C8W5W2
names: Similarity
messages: Belongs to the peptidase S11 family.

485916:DTOX RS05100
gene id: 485916:DTOX_RS05100
uniprot id: C8W482
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

485916:DTOX RS05670
gene id: 485916:DTOX_RS05670
uniprot id: C8W580
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

485916:DTOX RS03575
gene id: 485916:DTOX_RS03575
uniprot id: C8W1K3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

485916:DTOX RS02735
gene id: 485916:DTOX_RS02735
uniprot id: C8W622
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

485916:DTOX RS03670
gene id: 485916:DTOX_RS03670
uniprot id: C8W202
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

485916:DTOX RS04735
gene id: 485916:DTOX_RS04735
uniprot id: C8W3A5
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

485916:DTOX RS13815
gene id: 485916:DTOX_RS13815
uniprot id: C8W2C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

485916:DTOX RS10760
gene id: 485916:DTOX_RS10760
uniprot id: C8VZN6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

485916:DTOX RS20970
gene id: 485916:DTOX_RS20970
uniprot id: C8W036
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

485916:DTOX RS13860
gene id: 485916:DTOX_RS13860
uniprot id: C8W2D7
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS15530
gene id: 485916:DTOX_RS15530
uniprot id: C8W4Q7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

485916:DTOX RS02830
gene id: 485916:DTOX_RS02830
uniprot id: C8W640
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

485916:DTOX RS01555
gene id: 485916:DTOX_RS01555
uniprot id: C8W402
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

485916:DTOX RS14640
gene id: 485916:DTOX_RS14640
uniprot id: C8W3I8
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

485916:DTOX RS05105
gene id: 485916:DTOX_RS05105
uniprot id: C8W483
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

485916:DTOX RS20590
gene id: 485916:DTOX_RS20590
uniprot id: C8VZJ1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

485916:DTOX RS00240
gene id: 485916:DTOX_RS00240
uniprot id: C8VVD8
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

485916:DTOX RS06985
gene id: 485916:DTOX_RS06985
uniprot id: C8VVJ0
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

485916:DTOX RS09840
gene id: 485916:DTOX_RS09840
uniprot id: C8VYF3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

485916:DTOX RS13790
gene id: 485916:DTOX_RS13790
uniprot id: C8W1Y6
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

485916:DTOX RS03335
gene id: 485916:DTOX_RS03335
uniprot id: C8W1F5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

485916:DTOX RS07595
gene id: 485916:DTOX_RS07595
uniprot id: C8VW65
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS13235
gene id: 485916:DTOX_RS13235
uniprot id: C8W1M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

485916:DTOX RS11730
gene id: 485916:DTOX_RS11730
uniprot id: C8W0F2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

485916:DTOX RS19840
gene id: 485916:DTOX_RS19840
uniprot id: C8VYR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

485916:DTOX RS12670
gene id: 485916:DTOX_RS12670
uniprot id: C8W0Y6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS10350
gene id: 485916:DTOX_RS10350
uniprot id: C8VZ21
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

485916:DTOX RS02975
gene id: 485916:DTOX_RS02975
uniprot id: C8W670
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

485916:DTOX RS05035
gene id: 485916:DTOX_RS05035
uniprot id: C8W469
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

485916:DTOX RS16955
gene id: 485916:DTOX_RS16955
uniprot id: C8W6W0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

485916:DTOX RS01630
gene id: 485916:DTOX_RS01630
uniprot id: C8W417
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS02195
gene id: 485916:DTOX_RS02195
uniprot id: C8W519
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

485916:DTOX RS00260
gene id: 485916:DTOX_RS00260
uniprot id: C8VVE2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS05705
gene id: 485916:DTOX_RS05705
uniprot id: C8W587
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

485916:DTOX RS04525
gene id: 485916:DTOX_RS04525
uniprot id: C8W366
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS19710
gene id: 485916:DTOX_RS19710
uniprot id: C8VYN7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

485916:DTOX RS12640
gene id: 485916:DTOX_RS12640
uniprot id: C8W0Y0
names: Similarity
messages: Belongs to the TlyA family.

485916:DTOX RS04415
gene id: 485916:DTOX_RS04415
uniprot id: C8W344
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

485916:DTOX RS07395
gene id: 485916:DTOX_RS07395
uniprot id: C8VVR6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS10180
gene id: 485916:DTOX_RS10180
uniprot id: C8VYY5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

485916:DTOX RS02940
gene id: 485916:DTOX_RS02940
uniprot id: C8W663
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

485916:DTOX RS08360
gene id: 485916:DTOX_RS08360
uniprot id: C8VWZ0
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

485916:DTOX RS14635
gene id: 485916:DTOX_RS14635
uniprot id: C8W3I7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

485916:DTOX RS20050
gene id: 485916:DTOX_RS20050
uniprot id: C8VYV3
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

485916:DTOX RS10620
gene id: 485916:DTOX_RS10620
uniprot id: C8VZ77
names: Similarity
messages: Belongs to the EamA transporter family.

485916:DTOX RS20160
gene id: 485916:DTOX_RS20160
uniprot id: C8VZA1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

485916:DTOX RS04540
gene id: 485916:DTOX_RS04540
uniprot id: C8W369
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

485916:DTOX RS20770
gene id: 485916:DTOX_RS20770
uniprot id: C8W003
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

485916:DTOX RS18375
gene id: 485916:DTOX_RS18375
uniprot id: C8VX97
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS21040
gene id: 485916:DTOX_RS21040
uniprot id: C8W049
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

485916:DTOX RS20155
gene id: 485916:DTOX_RS20155
uniprot id: C8VZA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS19915
gene id: 485916:DTOX_RS19915
uniprot id: C8VYS7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

485916:DTOX RS16265
gene id: 485916:DTOX_RS16265
uniprot id: C8W5T5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

485916:DTOX RS12820
gene id: 485916:DTOX_RS12820
uniprot id: C8W117
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

485916:DTOX RS11610
gene id: 485916:DTOX_RS11610
uniprot id: C8W0C8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

485916:DTOX RS06565
gene id: 485916:DTOX_RS06565
uniprot id: C8W6E1
names: Similarity
messages: Belongs to the HdrA family.

485916:DTOX RS09925
gene id: 485916:DTOX_RS09925
uniprot id: C8VYH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

485916:DTOX RS13140
gene id: 485916:DTOX_RS13140
uniprot id: C8W181
names: Similarity
messages: Belongs to the peptidase U62 family.

485916:DTOX RS11290
gene id: 485916:DTOX_RS11290
uniprot id: C8VZZ1
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS00600
gene id: 485916:DTOX_RS00600
uniprot id: C8W2S6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

485916:DTOX RS11670
gene id: 485916:DTOX_RS11670
uniprot id: C8W0E0
names: Similarity
messages: Belongs to the UPF0111 family.

485916:DTOX RS04855
gene id: 485916:DTOX_RS04855
uniprot id: C8W3D2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS01210
gene id: 485916:DTOX_RS01210
uniprot id: C8W3U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

485916:DTOX RS21700
gene id: 485916:DTOX_RS21700
uniprot id: C8W6T6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

485916:DTOX RS16030
gene id: 485916:DTOX_RS16030
uniprot id: C8W5N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

485916:DTOX RS03340
gene id: 485916:DTOX_RS03340
uniprot id: C8W1F6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

485916:DTOX RS01350
gene id: 485916:DTOX_RS01350
uniprot id: C8W3W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

485916:DTOX RS19780
gene id: 485916:DTOX_RS19780
uniprot id: C8VYQ2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

485916:DTOX RS13705
gene id: 485916:DTOX_RS13705
uniprot id: C8W1W9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

485916:DTOX RS05145
gene id: 485916:DTOX_RS05145
uniprot id: C8W490
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

485916:DTOX RS01030
gene id: 485916:DTOX_RS01030
uniprot id: C8W303
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

485916:DTOX RS01610
gene id: 485916:DTOX_RS01610
uniprot id: C8W413
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

485916:DTOX RS02710
gene id: 485916:DTOX_RS02710
uniprot id: C8W617
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS04820
gene id: 485916:DTOX_RS04820
uniprot id: C8W3C5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

485916:DTOX RS02430
gene id: 485916:DTOX_RS02430
uniprot id: C8W5W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS11830
gene id: 485916:DTOX_RS11830
uniprot id: C8W0H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

485916:DTOX RS11240
gene id: 485916:DTOX_RS11240
uniprot id: C8VZY1
names: Similarity
messages: Belongs to the NadC/ModD family.

485916:DTOX RS11955
gene id: 485916:DTOX_RS11955
uniprot id: C8W0J4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS00375
gene id: 485916:DTOX_RS00375
uniprot id: C8VVF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

485916:DTOX RS14475
gene id: 485916:DTOX_RS14475
uniprot id: C8W3F6
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

485916:DTOX RS05690
gene id: 485916:DTOX_RS05690
uniprot id: C8W584
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

485916:DTOX RS07900
gene id: 485916:DTOX_RS07900
uniprot id: C8VWC3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS00370
gene id: 485916:DTOX_RS00370
uniprot id: C8VVH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS01495
gene id: 485916:DTOX_RS01495
uniprot id: C8W3Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

485916:DTOX RS05655
gene id: 485916:DTOX_RS05655
uniprot id: C8W577
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

485916:DTOX RS08055
gene id: 485916:DTOX_RS08055
uniprot id: C8VWF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

485916:DTOX RS00045
gene id: 485916:DTOX_RS00045
uniprot id: C8VVA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

485916:DTOX RS16310
gene id: 485916:DTOX_RS16310
uniprot id: C8W5U4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

485916:DTOX RS01025
gene id: 485916:DTOX_RS01025
uniprot id: C8W302
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS08280
gene id: 485916:DTOX_RS08280
uniprot id: C8VWX3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

485916:DTOX RS00525
gene id: 485916:DTOX_RS00525
uniprot id: C8W2R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

485916:DTOX RS03660
gene id: 485916:DTOX_RS03660
uniprot id: C8W200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

485916:DTOX RS08570
gene id: 485916:DTOX_RS08570
uniprot id: C8VX32
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

485916:DTOX RS08210
gene id: 485916:DTOX_RS08210
uniprot id: C8VWV9
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS05060
gene id: 485916:DTOX_RS05060
uniprot id: C8W474
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

485916:DTOX RS00495
gene id: 485916:DTOX_RS00495
uniprot id: C8W2Q3
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

485916:DTOX RS04520
gene id: 485916:DTOX_RS04520
uniprot id: C8W365
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS18095
gene id: 485916:DTOX_RS18095
uniprot id: C8VWS4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

485916:DTOX RS21115
gene id: 485916:DTOX_RS21115
uniprot id: C8W065
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

485916:DTOX RS16210
gene id: 485916:DTOX_RS16210
uniprot id: C8W5S5
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS15720
gene id: 485916:DTOX_RS15720
uniprot id: C8W4U3
names: Similarity
messages: Belongs to the GSP E family.

485916:DTOX RS17375
gene id: 485916:DTOX_RS17375
uniprot id: C8VW00
names: Similarity
messages: Belongs to the HdrA family.

485916:DTOX RS19470
gene id: 485916:DTOX_RS19470
uniprot id: C8VY75
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

485916:DTOX RS16355
gene id: 485916:DTOX_RS16355
uniprot id: C8W5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

485916:DTOX RS05855
gene id: 485916:DTOX_RS05855
uniprot id: C8W5B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

485916:DTOX RS10270
gene id: 485916:DTOX_RS10270
uniprot id: C8VZ04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

485916:DTOX RS03885
gene id: 485916:DTOX_RS03885
uniprot id: C8W245
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

485916:DTOX RS00500
gene id: 485916:DTOX_RS00500
uniprot id: C8W2Q6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

485916:DTOX RS13800
gene id: 485916:DTOX_RS13800
uniprot id: C8W2C5
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS13490
gene id: 485916:DTOX_RS13490
uniprot id: C8W1S8
names: Similarity
messages: Belongs to the TrpC family.

485916:DTOX RS08245
gene id: 485916:DTOX_RS08245
uniprot id: C8VWW6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS16985
gene id: 485916:DTOX_RS16985
uniprot id: C8VVT7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

485916:DTOX RS15595
gene id: 485916:DTOX_RS15595
uniprot id: C8W4R9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

485916:DTOX RS08050
gene id: 485916:DTOX_RS08050
uniprot id: C8VWF0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

485916:DTOX RS01295
gene id: 485916:DTOX_RS01295
uniprot id: C8W3V4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

485916:DTOX RS18520
gene id: 485916:DTOX_RS18520
uniprot id: C8VXC4
names: Similarity
messages: Belongs to the universal stress protein A family.

485916:DTOX RS09980
gene id: 485916:DTOX_RS09980
uniprot id: C8VYI1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

485916:DTOX RS08170
gene id: 485916:DTOX_RS08170
uniprot id: C8VWV1
names: Similarity
messages: Belongs to the ThiD family.

485916:DTOX RS15055
gene id: 485916:DTOX_RS15055
uniprot id: C8W3R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

485916:DTOX RS12685
gene id: 485916:DTOX_RS12685
uniprot id: C8W0Y9
names: Similarity
messages: Belongs to the EamA transporter family.

485916:DTOX RS02915
gene id: 485916:DTOX_RS02915
uniprot id: C8W658
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS15065
gene id: 485916:DTOX_RS15065
uniprot id: C8W3S0
names: Similarity
messages: Belongs to the DEAD box helicase family.

485916:DTOX RS07830
gene id: 485916:DTOX_RS07830
uniprot id: C8VWA9
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

485916:DTOX RS10415
gene id: 485916:DTOX_RS10415
uniprot id: C8VZ34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

485916:DTOX RS05870
gene id: 485916:DTOX_RS05870
uniprot id: C8W5C1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS19890
gene id: 485916:DTOX_RS19890
uniprot id: C8VYS3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

485916:DTOX RS16645
gene id: 485916:DTOX_RS16645
uniprot id: C8W6Q4
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

485916:DTOX RS02905
gene id: 485916:DTOX_RS02905
uniprot id: C8W655
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

485916:DTOX RS05425
gene id: 485916:DTOX_RS05425
uniprot id: C8W4E6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

485916:DTOX RS01090
gene id: 485916:DTOX_RS01090
uniprot id: C8W316
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

485916:DTOX RS17930
gene id: 485916:DTOX_RS17930
uniprot id: C8VWN9
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

485916:DTOX RS03980
gene id: 485916:DTOX_RS03980
uniprot id: C8W264
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

485916:DTOX RS15450
gene id: 485916:DTOX_RS15450
uniprot id: C8W4P1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

485916:DTOX RS08525
gene id: 485916:DTOX_RS08525
uniprot id: C8VX23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

485916:DTOX RS01895
gene id: 485916:DTOX_RS01895
uniprot id: C8W4X0
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS02620
gene id: 485916:DTOX_RS02620
uniprot id: C8W5Z9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

485916:DTOX RS12555
gene id: 485916:DTOX_RS12555
uniprot id: C8W0V4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

485916:DTOX RS10465
gene id: 485916:DTOX_RS10465
uniprot id: C8VZ45
names: Similarity
messages: Belongs to the histone deacetylase family.

485916:DTOX RS14325
gene id: 485916:DTOX_RS14325
uniprot id: C8W2M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

485916:DTOX RS01470
gene id: 485916:DTOX_RS01470
uniprot id: C8W3Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

485916:DTOX RS03865
gene id: 485916:DTOX_RS03865
uniprot id: C8W240
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

485916:DTOX RS15575
gene id: 485916:DTOX_RS15575
uniprot id: C8W4R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

485916:DTOX RS14570
gene id: 485916:DTOX_RS14570
uniprot id: C8W3H4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS18540
gene id: 485916:DTOX_RS18540
uniprot id: C8VXC8
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS11605
gene id: 485916:DTOX_RS11605
uniprot id: C8W0C7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

485916:DTOX RS16465
gene id: 485916:DTOX_RS16465
uniprot id: C8W6L6
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS15585
gene id: 485916:DTOX_RS15585
uniprot id: C8W4R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

485916:DTOX RS12655
gene id: 485916:DTOX_RS12655
uniprot id: C8W0Y3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

485916:DTOX RS14355
gene id: 485916:DTOX_RS14355
uniprot id: C8W2N4
names: Subcellular Location Annotation
messages: Cytoplasm

485916:DTOX RS14655
gene id: 485916:DTOX_RS14655
uniprot id: C8W3J1
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

485916:DTOX RS08880
gene id: 485916:DTOX_RS08880
uniprot id: C8VXL1
names: Similarity
messages: Belongs to the type IA topoisomerase family.

485916:DTOX RS19850
gene id: 485916:DTOX_RS19850
uniprot id: C8VYR5
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS00635
gene id: 485916:DTOX_RS00635
uniprot id: C8W2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

485916:DTOX RS05935
gene id: 485916:DTOX_RS05935
uniprot id: C8W5D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

485916:DTOX RS20180
gene id: 485916:DTOX_RS20180
uniprot id: C8VZA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS12675
gene id: 485916:DTOX_RS12675
uniprot id: C8W0Y7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

485916:DTOX RS15215
gene id: 485916:DTOX_RS15215
uniprot id: C8W4J8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

485916:DTOX RS00860
gene id: 485916:DTOX_RS00860
uniprot id: C8W2W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

485916:DTOX RS11420
gene id: 485916:DTOX_RS11420
uniprot id: C8W090
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

485916:DTOX RS03810
gene id: 485916:DTOX_RS03810
uniprot id: C8W230
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

485916:DTOX RS19815
gene id: 485916:DTOX_RS19815
uniprot id: C8VYQ7
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS11235
gene id: 485916:DTOX_RS11235
uniprot id: C8VZY0
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

485916:DTOX RS05225
gene id: 485916:DTOX_RS05225
uniprot id: C8W4A6
names: Similarity
messages: Belongs to the UPF0235 family.

485916:DTOX RS02350
gene id: 485916:DTOX_RS02350
uniprot id: C8W549
names: Similarity
messages: Belongs to the EamA transporter family.

485916:DTOX RS15000
gene id: 485916:DTOX_RS15000
uniprot id: C8W3Q7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

485916:DTOX RS17540
gene id: 485916:DTOX_RS17540
uniprot id: C8VW38
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

485916:DTOX RS01225
gene id: 485916:DTOX_RS01225
uniprot id: C8W3U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

485916:DTOX RS12710
gene id: 485916:DTOX_RS12710
uniprot id: C8W0Z4
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

485916:DTOX RS15015
gene id: 485916:DTOX_RS15015
uniprot id: C8W3R0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

485916:DTOX RS05465
gene id: 485916:DTOX_RS05465
uniprot id: C8W4F4
names: Function
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

485916:DTOX RS10075
gene id: 485916:DTOX_RS10075
uniprot id: C8VYW4
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS16090
gene id: 485916:DTOX_RS16090
uniprot id: C8W5Q0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

485916:DTOX RS05045
gene id: 485916:DTOX_RS05045
uniprot id: C8W471
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

485916:DTOX RS01045
gene id: 485916:DTOX_RS01045
uniprot id: C8W306
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

485916:DTOX RS10120
gene id: 485916:DTOX_RS10120
uniprot id: C8VYX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

485916:DTOX RS03955
gene id: 485916:DTOX_RS03955
uniprot id: C8W259
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

485916:DTOX RS07610
gene id: 485916:DTOX_RS07610
uniprot id: C8VW68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

485916:DTOX RS05540
gene id: 485916:DTOX_RS05540
uniprot id: C8W4G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

485916:DTOX RS10810
gene id: 485916:DTOX_RS10810
uniprot id: C8VZP6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

485916:DTOX RS17395
gene id: 485916:DTOX_RS17395
uniprot id: C8VW04
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

485916:DTOX RS10080
gene id: 485916:DTOX_RS10080
uniprot id: C8VYW5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

485916:DTOX RS05250
gene id: 485916:DTOX_RS05250
uniprot id: C8W4B1
names: Similarity
messages: Belongs to the CapA family.

485916:DTOX RS19825
gene id: 485916:DTOX_RS19825
uniprot id: C8VYQ9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

485916:DTOX RS20280
gene id: 485916:DTOX_RS20280
uniprot id: C8VZC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

485916:DTOX RS04155
gene id: 485916:DTOX_RS04155
uniprot id: C8W298
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

485916:DTOX RS08915
gene id: 485916:DTOX_RS08915
uniprot id: C8VXL2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS08775
gene id: 485916:DTOX_RS08775
uniprot id: C8VXJ0
names: Similarity
messages: Belongs to the FBPase class 2 family.

485916:DTOX RS18675
gene id: 485916:DTOX_RS18675
uniprot id: C8VXF5
names: Similarity
messages: Belongs to the universal stress protein A family.

485916:DTOX RS05420
gene id: 485916:DTOX_RS05420
uniprot id: C8W4E5
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS11570
gene id: 485916:DTOX_RS11570
uniprot id: C8W0C0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

485916:DTOX RS08125
gene id: 485916:DTOX_RS08125
uniprot id: C8VWG6
names: Similarity
messages: Belongs to the UPF0751 family.

485916:DTOX RS07490
gene id: 485916:DTOX_RS07490
uniprot id: C8VVT5
names: Similarity
messages: Belongs to the Vsr family.

485916:DTOX RS06630
gene id: 485916:DTOX_RS06630
uniprot id: C8W6F3
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS04310
gene id: 485916:DTOX_RS04310
uniprot id: C8W323
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

485916:DTOX RS03285
gene id: 485916:DTOX_RS03285
uniprot id: C8W1E2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

485916:DTOX RS03695
gene id: 485916:DTOX_RS03695
uniprot id: C8W207
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS19065
gene id: 485916:DTOX_RS19065
uniprot id: C8VXZ7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

485916:DTOX RS13305
gene id: 485916:DTOX_RS13305
uniprot id: C8W1P1
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS01575
gene id: 485916:DTOX_RS01575
uniprot id: C8W406
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

485916:DTOX RS01215
gene id: 485916:DTOX_RS01215
uniprot id: C8W3U3
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

485916:DTOX RS14265
gene id: 485916:DTOX_RS14265
uniprot id: C8W2L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS11340
gene id: 485916:DTOX_RS11340
uniprot id: C8W074
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS04150
gene id: 485916:DTOX_RS04150
uniprot id: C8W297
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

485916:DTOX RS13315
gene id: 485916:DTOX_RS13315
uniprot id: C8W1P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

485916:DTOX RS01435
gene id: 485916:DTOX_RS01435
uniprot id: C8W3X8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

485916:DTOX RS15465
gene id: 485916:DTOX_RS15465
uniprot id: C8W4P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

485916:DTOX RS20250
gene id: 485916:DTOX_RS20250
uniprot id: C8VZB9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS04260
gene id: 485916:DTOX_RS04260
uniprot id: C8W2B6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

485916:DTOX RS10385
gene id: 485916:DTOX_RS10385
uniprot id: C8VZ28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

485916:DTOX RS19885
gene id: 485916:DTOX_RS19885
uniprot id: C8VYS2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

485916:DTOX RS05525
gene id: 485916:DTOX_RS05525
uniprot id: C8W4G5
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS03550
gene id: 485916:DTOX_RS03550
uniprot id: C8W1J8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

485916:DTOX RS02895
gene id: 485916:DTOX_RS02895
uniprot id: C8W653
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

485916:DTOX RS15635
gene id: 485916:DTOX_RS15635
uniprot id: C8W4S7
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

485916:DTOX RS23930
gene id: 485916:DTOX_RS23930
uniprot id: C8W1V8
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS05905
gene id: 485916:DTOX_RS05905
uniprot id: C8W5C8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

485916:DTOX RS15535
gene id: 485916:DTOX_RS15535
uniprot id: C8W4Q8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

485916:DTOX RS02560
gene id: 485916:DTOX_RS02560
uniprot id: C8W5Y6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

485916:DTOX RS05050
gene id: 485916:DTOX_RS05050
uniprot id: C8W472
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS14545
gene id: 485916:DTOX_RS14545
uniprot id: C8W3G9
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

485916:DTOX RS17610
gene id: 485916:DTOX_RS17610
uniprot id: C8VWH3
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

485916:DTOX RS02615
gene id: 485916:DTOX_RS02615
uniprot id: C8W5Z8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS10380
gene id: 485916:DTOX_RS10380
uniprot id: C8VZ27
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

485916:DTOX RS06040
gene id: 485916:DTOX_RS06040
uniprot id: C8W5F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

485916:DTOX RS06875
gene id: 485916:DTOX_RS06875
uniprot id: C8VVH4
names: Similarity
messages: Belongs to the 'phage' integrase family.

485916:DTOX RS18805
gene id: 485916:DTOX_RS18805
uniprot id: C8VXH8
names: Similarity
messages: Belongs to the PemK/MazF family.

485916:DTOX RS17565
gene id: 485916:DTOX_RS17565
uniprot id: C8VW43
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

485916:DTOX RS05020
gene id: 485916:DTOX_RS05020
uniprot id: C8W465
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS20125
gene id: 485916:DTOX_RS20125
uniprot id: C8VZ94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

485916:DTOX RS01145
gene id: 485916:DTOX_RS01145
uniprot id: C8W3S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

485916:DTOX RS15625
gene id: 485916:DTOX_RS15625
uniprot id: C8W4S5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

485916:DTOX RS02260
gene id: 485916:DTOX_RS02260
uniprot id: C8W532
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

485916:DTOX RS05840
gene id: 485916:DTOX_RS05840
uniprot id: C8W5B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

485916:DTOX RS19985
gene id: 485916:DTOX_RS19985
uniprot id: C8VYU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

485916:DTOX RS16260
gene id: 485916:DTOX_RS16260
uniprot id: C8W5T4
names: Similarity
messages: Belongs to the peptidase S16 family.

485916:DTOX RS13300
gene id: 485916:DTOX_RS13300
uniprot id: C8W1P0
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS10390
gene id: 485916:DTOX_RS10390
uniprot id: C8VZ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

485916:DTOX RS12850
gene id: 485916:DTOX_RS12850
uniprot id: C8W120
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS12490
gene id: 485916:DTOX_RS12490
uniprot id: C8W0U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS03975
gene id: 485916:DTOX_RS03975
uniprot id: C8W263
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

485916:DTOX RS01875
gene id: 485916:DTOX_RS01875
uniprot id: C8W4W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS02815
gene id: 485916:DTOX_RS02815
uniprot id: C8W637
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

485916:DTOX RS17330
gene id: 485916:DTOX_RS17330
uniprot id: C8VVZ1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

485916:DTOX RS01500
gene id: 485916:DTOX_RS01500
uniprot id: C8W3Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

485916:DTOX RS04315
gene id: 485916:DTOX_RS04315
uniprot id: C8W324
names: Similarity
messages: Belongs to the phosphohexose mutase family.

485916:DTOX RS12380
gene id: 485916:DTOX_RS12380
uniprot id: C8W0S3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

485916:DTOX RS09220
gene id: 485916:DTOX_RS09220
uniprot id: C8VXR7
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

485916:DTOX RS01410
gene id: 485916:DTOX_RS01410
uniprot id: C8W3X3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

485916:DTOX RS17165
gene id: 485916:DTOX_RS17165
uniprot id: C8VVX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

485916:DTOX RS13895
gene id: 485916:DTOX_RS13895
uniprot id: C8W2E4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

485916:DTOX RS05330
gene id: 485916:DTOX_RS05330
uniprot id: C8W4C8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

485916:DTOX RS20190
gene id: 485916:DTOX_RS20190
uniprot id: C8VZA7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

485916:DTOX RS16215
gene id: 485916:DTOX_RS16215
uniprot id: C8W5S6
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

485916:DTOX RS05555
gene id: 485916:DTOX_RS05555
uniprot id: C8W4H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

485916:DTOX RS14270
gene id: 485916:DTOX_RS14270
uniprot id: C8W2L7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

485916:DTOX RS21055
gene id: 485916:DTOX_RS21055
uniprot id: C8W052
names: Similarity
messages: Belongs to the peptidase M18 family.

485916:DTOX RS20265
gene id: 485916:DTOX_RS20265
uniprot id: C8VZC2
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

485916:DTOX RS21095
gene id: 485916:DTOX_RS21095
uniprot id: C8W060
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS13840
gene id: 485916:DTOX_RS13840
uniprot id: C8W2D3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

485916:DTOX RS19990
gene id: 485916:DTOX_RS19990
uniprot id: C8VYU2
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS02235
gene id: 485916:DTOX_RS02235
uniprot id: C8W527
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS17405
gene id: 485916:DTOX_RS17405
uniprot id: C8VW06
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

485916:DTOX RS12175
gene id: 485916:DTOX_RS12175
uniprot id: C8W0P0
names: Similarity
messages: Belongs to the GSP E family.

485916:DTOX RS06800
gene id: 485916:DTOX_RS06800
uniprot id: C8W6I5
names: Similarity
messages: Belongs to the CapA family.

485916:DTOX RS05765
gene id: 485916:DTOX_RS05765
uniprot id: C8W599
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

485916:DTOX RS05290
gene id: 485916:DTOX_RS05290
uniprot id: C8W4B9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

485916:DTOX RS19070
gene id: 485916:DTOX_RS19070
uniprot id: C8VXZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

485916:DTOX RS08430
gene id: 485916:DTOX_RS08430
uniprot id: C8VX04
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS00935
gene id: 485916:DTOX_RS00935
uniprot id: C8W2Y4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

485916:DTOX RS05795
gene id: 485916:DTOX_RS05795
uniprot id: C8W5A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

485916:DTOX RS12235
gene id: 485916:DTOX_RS12235
uniprot id: C8W0P9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

485916:DTOX RS01330
gene id: 485916:DTOX_RS01330
uniprot id: C8W3W1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS11330
gene id: 485916:DTOX_RS11330
uniprot id: C8W072
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

485916:DTOX RS09870
gene id: 485916:DTOX_RS09870
uniprot id: C8VYF9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

485916:DTOX RS11360
gene id: 485916:DTOX_RS11360
uniprot id: C8W078
names: Similarity
messages: Belongs to the YicC/YloC family.

485916:DTOX RS01290
gene id: 485916:DTOX_RS01290
uniprot id: C8W3V3
names: Caution
names: Function
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS06640
gene id: 485916:DTOX_RS06640
uniprot id: C8W6F5
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS19650
gene id: 485916:DTOX_RS19650
uniprot id: C8VYM3
names: Similarity
messages: Belongs to the UPF0175 family.

485916:DTOX RS04405
gene id: 485916:DTOX_RS04405
uniprot id: C8W342
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

485916:DTOX RS15410
gene id: 485916:DTOX_RS15410
uniprot id: C8W4N3
names: Similarity
messages: Belongs to the peptidase M16 family.

485916:DTOX RS03565
gene id: 485916:DTOX_RS03565
uniprot id: C8W1K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

485916:DTOX RS11390
gene id: 485916:DTOX_RS11390
uniprot id: C8W084
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS18235
gene id: 485916:DTOX_RS18235
uniprot id: C8VX69
names: Similarity
messages: Belongs to the glutamate synthase family.

485916:DTOX RS05560
gene id: 485916:DTOX_RS05560
uniprot id: C8W4H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

485916:DTOX RS06050
gene id: 485916:DTOX_RS06050
uniprot id: C8W5F6
names: Similarity
messages: Belongs to the Ahb/Nir family.

485916:DTOX RS03395
gene id: 485916:DTOX_RS03395
uniprot id: C8W1G7
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

485916:DTOX RS13370
gene id: 485916:DTOX_RS13370
uniprot id: C8W1Q3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS16340
gene id: 485916:DTOX_RS16340
uniprot id: C8W5V1
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS20090
gene id: 485916:DTOX_RS20090
uniprot id: C8VZ87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

485916:DTOX RS10480
gene id: 485916:DTOX_RS10480
uniprot id: C8VZ48
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

485916:DTOX RS06790
gene id: 485916:DTOX_RS06790
uniprot id: C8W6I3
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

485916:DTOX RS09950
gene id: 485916:DTOX_RS09950
uniprot id: C8VYH6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS10280
gene id: 485916:DTOX_RS10280
uniprot id: C8VZ06
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

485916:DTOX RS11030
gene id: 485916:DTOX_RS11030
uniprot id: C8VZT8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

485916:DTOX RS08495
gene id: 485916:DTOX_RS08495
uniprot id: C8VX18
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

485916:DTOX RS08835
gene id: 485916:DTOX_RS08835
uniprot id: C8VXK2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

485916:DTOX RS05325
gene id: 485916:DTOX_RS05325
uniprot id: C8W4C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

485916:DTOX RS18310
gene id: 485916:DTOX_RS18310
uniprot id: C8VX84
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS14415
gene id: 485916:DTOX_RS14415
uniprot id: C8W2P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

485916:DTOX RS15650
gene id: 485916:DTOX_RS15650
uniprot id: C8W4T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

485916:DTOX RS08805
gene id: 485916:DTOX_RS08805
uniprot id: C8VXJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS12945
gene id: 485916:DTOX_RS12945
uniprot id: C8W139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

485916:DTOX RS11505
gene id: 485916:DTOX_RS11505
uniprot id: C8W0A7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

485916:DTOX RS06405
gene id: 485916:DTOX_RS06405
uniprot id: C8W6B2
names: Similarity
messages: Belongs to the DprA/Smf family.

485916:DTOX RS08335
gene id: 485916:DTOX_RS08335
uniprot id: C8VWY4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

485916:DTOX RS05835
gene id: 485916:DTOX_RS05835
uniprot id: C8W5B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

485916:DTOX RS10285
gene id: 485916:DTOX_RS10285
uniprot id: C8VZ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS01340
gene id: 485916:DTOX_RS01340
uniprot id: C8W3W3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

485916:DTOX RS09940
gene id: 485916:DTOX_RS09940
uniprot id: C8VYH4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

485916:DTOX RS05295
gene id: 485916:DTOX_RS05295
uniprot id: C8W4C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

485916:DTOX RS06670
gene id: 485916:DTOX_RS06670
uniprot id: C8W6G1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

485916:DTOX RS18155
gene id: 485916:DTOX_RS18155
uniprot id: C8VWT4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS17590
gene id: 485916:DTOX_RS17590
uniprot id: C8VW46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

485916:DTOX RS05010
gene id: 485916:DTOX_RS05010
uniprot id: C8W463
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

485916:DTOX RS00865
gene id: 485916:DTOX_RS00865
uniprot id: C8W2X0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

485916:DTOX RS20130
gene id: 485916:DTOX_RS20130
uniprot id: C8VZ95
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS02800
gene id: 485916:DTOX_RS02800
uniprot id: C8W634
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

485916:DTOX RS14740
gene id: 485916:DTOX_RS14740
uniprot id: C8W3K4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

485916:DTOX RS21310
gene id: 485916:DTOX_RS21310
uniprot id: C8W3D5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

485916:DTOX RS15845
gene id: 485916:DTOX_RS15845
uniprot id: C8W5K3
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS03870
gene id: 485916:DTOX_RS03870
uniprot id: C8W241
names: Similarity
messages: Belongs to the FrhG family.

485916:DTOX RS05780
gene id: 485916:DTOX_RS05780
uniprot id: C8W5A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

485916:DTOX RS01605
gene id: 485916:DTOX_RS01605
uniprot id: C8W412
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

485916:DTOX RS04770
gene id: 485916:DTOX_RS04770
uniprot id: C8W3B2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS07750
gene id: 485916:DTOX_RS07750
uniprot id: C8VW94
names: Similarity
messages: Belongs to the ABC transporter superfamily.

485916:DTOX RS00485
gene id: 485916:DTOX_RS00485
uniprot id: C8W2Q1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

485916:DTOX RS03860
gene id: 485916:DTOX_RS03860
uniprot id: C8W239
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

485916:DTOX RS10290
gene id: 485916:DTOX_RS10290
uniprot id: C8VZ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

485916:DTOX RS19075
gene id: 485916:DTOX_RS19075
uniprot id: C8VXZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

485916:DTOX RS03650
gene id: 485916:DTOX_RS03650
uniprot id: C8W1L7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

485916:DTOX RS11455
gene id: 485916:DTOX_RS11455
uniprot id: C8W096
names: Similarity
messages: Belongs to the asparagine synthetase family.

485916:DTOX RS00540
gene id: 485916:DTOX_RS00540
uniprot id: C8W2R3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

485916:DTOX RS14630
gene id: 485916:DTOX_RS14630
uniprot id: C8W3I6
names: Similarity
messages: Belongs to the AAA ATPase family.

485916:DTOX RS11530
gene id: 485916:DTOX_RS11530
uniprot id: C8W0B2
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

485916:DTOX RS01595
gene id: 485916:DTOX_RS01595
uniprot id: C8W410
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

485916:DTOX RS01070
gene id: 485916:DTOX_RS01070
uniprot id: C8W311
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

485916:DTOX RS19950
gene id: 485916:DTOX_RS19950
uniprot id: C8VYT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS20100
gene id: 485916:DTOX_RS20100
uniprot id: C8VZ89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

485916:DTOX RS14785
gene id: 485916:DTOX_RS14785
uniprot id: C8W3L4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

485916:DTOX RS14780
gene id: 485916:DTOX_RS14780
uniprot id: C8W3L3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

485916:DTOX RS05805
gene id: 485916:DTOX_RS05805
uniprot id: C8W5A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

485916:DTOX RS13900
gene id: 485916:DTOX_RS13900
uniprot id: C8W2E5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

485916:DTOX RS14405
gene id: 485916:DTOX_RS14405
uniprot id: C8W2P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

485916:DTOX RS17340
gene id: 485916:DTOX_RS17340
uniprot id: C8VVZ3
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

485916:DTOX RS14730
gene id: 485916:DTOX_RS14730
uniprot id: C8W3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

485916:DTOX RS07715
gene id: 485916:DTOX_RS07715
uniprot id: C8VW87
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS06500
gene id: 485916:DTOX_RS06500
uniprot id: C8W6C8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

485916:DTOX RS12660
gene id: 485916:DTOX_RS12660
uniprot id: C8W0Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

485916:DTOX RS11190
gene id: 485916:DTOX_RS11190
uniprot id: C8VZX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

485916:DTOX RS08590
gene id: 485916:DTOX_RS08590
uniprot id: C8VX36
names: Caution
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

485916:DTOX RS19630
gene id: 485916:DTOX_RS19630
uniprot id: C8VYL7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

485916:DTOX RS03635
gene id: 485916:DTOX_RS03635
uniprot id: C8W1L4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

485916:DTOX RS12635
gene id: 485916:DTOX_RS12635
uniprot id: C8W0X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS01550
gene id: 485916:DTOX_RS01550
uniprot id: C8W401
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

485916:DTOX RS12900
gene id: 485916:DTOX_RS12900
uniprot id: C8W131
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS03025
gene id: 485916:DTOX_RS03025
uniprot id: C8W0W6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

485916:DTOX RS15425
gene id: 485916:DTOX_RS15425
uniprot id: C8W4N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

485916:DTOX RS15010
gene id: 485916:DTOX_RS15010
uniprot id: C8W3Q9
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

485916:DTOX RS03845
gene id: 485916:DTOX_RS03845
uniprot id: C8W236
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

485916:DTOX RS12620
gene id: 485916:DTOX_RS12620
uniprot id: C8W0X6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

485916:DTOX RS16185
gene id: 485916:DTOX_RS16185
uniprot id: C8W5S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

485916:DTOX RS14170
gene id: 485916:DTOX_RS14170
uniprot id: C8W2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS12625
gene id: 485916:DTOX_RS12625
uniprot id: C8W0X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

485916:DTOX RS08600
gene id: 485916:DTOX_RS08600
uniprot id: C8VX38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

485916:DTOX RS01625
gene id: 485916:DTOX_RS01625
uniprot id: C8W416
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

485916:DTOX RS01565
gene id: 485916:DTOX_RS01565
uniprot id: C8W404
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

485916:DTOX RS11695
gene id: 485916:DTOX_RS11695
uniprot id: C8W0E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

485916:DTOX RS11035
gene id: 485916:DTOX_RS11035
uniprot id: C8VZT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

485916:DTOX RS04685
gene id: 485916:DTOX_RS04685
uniprot id: C8W395
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

485916:DTOX RS05320
gene id: 485916:DTOX_RS05320
uniprot id: C8W4C6
names: Similarity
messages: Belongs to the asp23 family.

485916:DTOX RS20195
gene id: 485916:DTOX_RS20195
uniprot id: C8VZA8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

485916:DTOX RS19705
gene id: 485916:DTOX_RS19705
uniprot id: C8VYN6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

485916:DTOX RS00940
gene id: 485916:DTOX_RS00940
uniprot id: C8W2Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS01170
gene id: 485916:DTOX_RS01170
uniprot id: C8W3T4
names: Similarity
messages: Belongs to the DHPS family.

485916:DTOX RS18305
gene id: 485916:DTOX_RS18305
uniprot id: C8VX83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

485916:DTOX RS16345
gene id: 485916:DTOX_RS16345
uniprot id: C8W5V2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

485916:DTOX RS19280
gene id: 485916:DTOX_RS19280
uniprot id: C8VY40
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

485916:DTOX RS09375
gene id: 485916:DTOX_RS09375
uniprot id: C8VXU6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

485916:DTOX RS05910
gene id: 485916:DTOX_RS05910
uniprot id: C8W5C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

485916:DTOX RS00180
gene id: 485916:DTOX_RS00180
uniprot id: C8VVC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS02910
gene id: 485916:DTOX_RS02910
uniprot id: C8W656
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

485916:DTOX RS14305
gene id: 485916:DTOX_RS14305
uniprot id: C8W2M4
names: Similarity
messages: Belongs to the GerABKA family.

485916:DTOX RS10440
gene id: 485916:DTOX_RS10440
uniprot id: C8VZ40
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

485916:DTOX RS16665
gene id: 485916:DTOX_RS16665
uniprot id: C8W6Q8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

485916:DTOX RS12165
gene id: 485916:DTOX_RS12165
uniprot id: C8W0N8
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS00335
gene id: 485916:DTOX_RS00335
uniprot id: C8VVG1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

485916:DTOX RS15555
gene id: 485916:DTOX_RS15555
uniprot id: C8W4R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

485916:DTOX RS08560
gene id: 485916:DTOX_RS08560
uniprot id: C8VX30
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

485916:DTOX RS00015
gene id: 485916:DTOX_RS00015
uniprot id: C8VVA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

485916:DTOX RS01050
gene id: 485916:DTOX_RS01050
uniprot id: C8W307
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

485916:DTOX RS13920
gene id: 485916:DTOX_RS13920
uniprot id: C8W2E9
names: Subcellular Location Annotation
messages: Secreted

485916:DTOX RS06665
gene id: 485916:DTOX_RS06665
uniprot id: C8W6G0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

485916:DTOX RS14250
gene id: 485916:DTOX_RS14250
uniprot id: C8W2L3
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

485916:DTOX RS17595
gene id: 485916:DTOX_RS17595
uniprot id: C8VW47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

485916:DTOX RS10175
gene id: 485916:DTOX_RS10175
uniprot id: C8VYY4
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

485916:DTOX RS14275
gene id: 485916:DTOX_RS14275
uniprot id: C8W2L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

485916:DTOX RS10395
gene id: 485916:DTOX_RS10395
uniprot id: C8VZ30
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

485916:DTOX RS05715
gene id: 485916:DTOX_RS05715
uniprot id: C8W589
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

485916:DTOX RS21420
gene id: 485916:DTOX_RS21420
uniprot id: C8VXM0
names: Similarity
messages: Belongs to the peptidase S8 family.

485916:DTOX RS03210
gene id: 485916:DTOX_RS03210
uniprot id: C8W1C7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

485916:DTOX RS13805
gene id: 485916:DTOX_RS13805
uniprot id: C8W2C6
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

485916:DTOX RS15915
gene id: 485916:DTOX_RS15915
uniprot id: C8W5L7
names: Similarity
messages: Belongs to the UPF0237 family.

485916:DTOX RS10745
gene id: 485916:DTOX_RS10745
uniprot id: C8VZN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

485916:DTOX RS20305
gene id: 485916:DTOX_RS20305
uniprot id: C8VZC9
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

485916:DTOX RS16670
gene id: 485916:DTOX_RS16670
uniprot id: C8W6Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

485916:DTOX RS01585
gene id: 485916:DTOX_RS01585
uniprot id: C8W408
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

485916:DTOX RS17555
gene id: 485916:DTOX_RS17555
uniprot id: C8VW41
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

485916:DTOX RS01485
gene id: 485916:DTOX_RS01485
uniprot id: C8W3Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

485916:DTOX RS01770
gene id: 485916:DTOX_RS01770
uniprot id: C8W4U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS13220
gene id: 485916:DTOX_RS13220
uniprot id: C8W1M2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

485916:DTOX RS18290
gene id: 485916:DTOX_RS18290
uniprot id: C8VX80
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

485916:DTOX RS05340
gene id: 485916:DTOX_RS05340
uniprot id: C8W4D0
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS13515
gene id: 485916:DTOX_RS13515
uniprot id: C8W1T2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

485916:DTOX RS03730
gene id: 485916:DTOX_RS03730
uniprot id: C8W214
names: Similarity
messages: Belongs to the Tlp family.

485916:DTOX RS20045
gene id: 485916:DTOX_RS20045
uniprot id: C8VYV2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

485916:DTOX RS01415
gene id: 485916:DTOX_RS01415
uniprot id: C8W3X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

485916:DTOX RS08025
gene id: 485916:DTOX_RS08025
uniprot id: C8VWE5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

485916:DTOX RS05845
gene id: 485916:DTOX_RS05845
uniprot id: C8W5B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

485916:DTOX RS05040
gene id: 485916:DTOX_RS05040
uniprot id: C8W470
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

485916:DTOX RS07380
gene id: 485916:DTOX_RS07380
uniprot id: C8VVR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

485916:DTOX RS02395
gene id: 485916:DTOX_RS02395
uniprot id: C8W5V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

485916:DTOX RS11630
gene id: 485916:DTOX_RS11630
uniprot id: C8W0D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

485916:DTOX RS13795
gene id: 485916:DTOX_RS13795
uniprot id: C8W2C4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS11550
gene id: 485916:DTOX_RS11550
uniprot id: C8W0B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

485916:DTOX RS08780
gene id: 485916:DTOX_RS08780
uniprot id: C8VXJ1
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS15985
gene id: 485916:DTOX_RS15985
uniprot id: C8W5N1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

485916:DTOX RS01240
gene id: 485916:DTOX_RS01240
uniprot id: C8W3U9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

485916:DTOX RS03520
gene id: 485916:DTOX_RS03520
uniprot id: C8W1J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

485916:DTOX RS01005
gene id: 485916:DTOX_RS01005
uniprot id: C8W2Z8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

485916:DTOX RS01530
gene id: 485916:DTOX_RS01530
uniprot id: C8W3Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

485916:DTOX RS04885
gene id: 485916:DTOX_RS04885
uniprot id: C8W3D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS02600
gene id: 485916:DTOX_RS02600
uniprot id: C8W5Z4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

485916:DTOX RS05460
gene id: 485916:DTOX_RS05460
uniprot id: C8W4F3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

485916:DTOX RS09855
gene id: 485916:DTOX_RS09855
uniprot id: C8VYF6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

485916:DTOX RS14610
gene id: 485916:DTOX_RS14610
uniprot id: C8W3I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

485916:DTOX RS07960
gene id: 485916:DTOX_RS07960
uniprot id: C8VWD2
names: Similarity
messages: Belongs to the asparagine synthetase family.

485916:DTOX RS05115
gene id: 485916:DTOX_RS05115
uniprot id: C8W485
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

485916:DTOX RS11825
gene id: 485916:DTOX_RS11825
uniprot id: C8W0H0
names: Similarity
messages: Belongs to the peptidase S41A family.

485916:DTOX RS00955
gene id: 485916:DTOX_RS00955
uniprot id: C8W2Y8
names: Similarity
messages: Belongs to the MG067/MG068/MG395 family.

485916:DTOX RS16315
gene id: 485916:DTOX_RS16315
uniprot id: C8W5U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.
messages: Membrane

485916:DTOX RS02810
gene id: 485916:DTOX_RS02810
uniprot id: C8W636
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

485916:DTOX RS01425
gene id: 485916:DTOX_RS01425
uniprot id: C8W3X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

485916:DTOX RS05770
gene id: 485916:DTOX_RS05770
uniprot id: C8W5A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

485916:DTOX RS18970
gene id: 485916:DTOX_RS18970
uniprot id: C8VXY0
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

485916:DTOX RS13915
gene id: 485916:DTOX_RS13915
uniprot id: C8W2E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

485916:DTOX RS01300
gene id: 485916:DTOX_RS01300
uniprot id: C8W3V5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

485916:DTOX RS11810
gene id: 485916:DTOX_RS11810
uniprot id: C8W0G7
names: Similarity
messages: Belongs to the universal stress protein A family.

485916:DTOX RS03195
gene id: 485916:DTOX_RS03195
uniprot id: C8W1C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

485916:DTOX RS01515
gene id: 485916:DTOX_RS01515
uniprot id: C8W3Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

485916:DTOX RS13480
gene id: 485916:DTOX_RS13480
uniprot id: C8W1S6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS11545
gene id: 485916:DTOX_RS11545
uniprot id: C8W0B5
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

485916:DTOX RS01200
gene id: 485916:DTOX_RS01200
uniprot id: C8W3U0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

485916:DTOX RS05885
gene id: 485916:DTOX_RS05885
uniprot id: C8W5C4
names: Similarity
messages: Belongs to the DprA/Smf family.

485916:DTOX RS08670
gene id: 485916:DTOX_RS08670
uniprot id: C8VX47
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

485916:DTOX RS11090
gene id: 485916:DTOX_RS11090
uniprot id: C8VZV0
names: Similarity
messages: Belongs to the UPF0473 family.

485916:DTOX RS07575
gene id: 485916:DTOX_RS07575
uniprot id: C8VW61
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

485916:DTOX RS20465
gene id: 485916:DTOX_RS20465
uniprot id: C8VZG3
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

485916:DTOX RS19245
gene id: 485916:DTOX_RS19245
uniprot id: C8VY33
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS01505
gene id: 485916:DTOX_RS01505
uniprot id: C8W3Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

485916:DTOX RS18400
gene id: 485916:DTOX_RS18400
uniprot id: C8VXA2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

485916:DTOX RS04995
gene id: 485916:DTOX_RS04995
uniprot id: C8W460
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS16965
gene id: 485916:DTOX_RS16965
uniprot id: C8W6W2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

485916:DTOX RS03135
gene id: 485916:DTOX_RS03135
uniprot id: C8W1B0
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS20875
gene id: 485916:DTOX_RS20875
uniprot id: C8W022
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS04835
gene id: 485916:DTOX_RS04835
uniprot id: C8W3C8
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

485916:DTOX RS15485
gene id: 485916:DTOX_RS15485
uniprot id: C8W4P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

485916:DTOX RS01520
gene id: 485916:DTOX_RS01520
uniprot id: C8W3Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

485916:DTOX RS05015
gene id: 485916:DTOX_RS05015
uniprot id: C8W464
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

485916:DTOX RS20085
gene id: 485916:DTOX_RS20085
uniprot id: C8VZ86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS10485
gene id: 485916:DTOX_RS10485
uniprot id: C8VZ49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

485916:DTOX RS21010
gene id: 485916:DTOX_RS21010
uniprot id: C8W043
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

485916:DTOX RS19735
gene id: 485916:DTOX_RS19735
uniprot id: C8VYP3
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS11800
gene id: 485916:DTOX_RS11800
uniprot id: C8W0G5
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

485916:DTOX RS03790
gene id: 485916:DTOX_RS03790
uniprot id: C8W226
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

485916:DTOX RS06480
gene id: 485916:DTOX_RS06480
uniprot id: C8W6C4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS03880
gene id: 485916:DTOX_RS03880
uniprot id: C8W244
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

485916:DTOX RS02240
gene id: 485916:DTOX_RS02240
uniprot id: C8W528
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS02770
gene id: 485916:DTOX_RS02770
uniprot id: C8W628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

485916:DTOX RS05255
gene id: 485916:DTOX_RS05255
uniprot id: C8W4B2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

485916:DTOX RS10510
gene id: 485916:DTOX_RS10510
uniprot id: C8VZ54
names: Similarity
messages: Belongs to the class-I fumarase family.

485916:DTOX RS00210
gene id: 485916:DTOX_RS00210
uniprot id: C8VVD2
names: Similarity
messages: Belongs to the SleB family.

485916:DTOX RS08305
gene id: 485916:DTOX_RS08305
uniprot id: C8VWX8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

485916:DTOX RS03705
gene id: 485916:DTOX_RS03705
uniprot id: C8W209
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS01790
gene id: 485916:DTOX_RS01790
uniprot id: C8W4V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485916:DTOX RS00890
gene id: 485916:DTOX_RS00890
uniprot id: C8W2X5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

485916:DTOX RS16195
gene id: 485916:DTOX_RS16195
uniprot id: C8W5S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

485916:DTOX RS19115
gene id: 485916:DTOX_RS19115
uniprot id: C8VY07
names: Similarity
messages: Belongs to the PGI/PMI family.

485916:DTOX RS00005
gene id: 485916:DTOX_RS00005
uniprot id: C8VV97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

485916:DTOX RS20680
gene id: 485916:DTOX_RS20680
uniprot id: C8VZL0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

485916:DTOX RS06615
gene id: 485916:DTOX_RS06615
uniprot id: C8W6F0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

485916:DTOX RS04815
gene id: 485916:DTOX_RS04815
uniprot id: C8W3C4
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

485916:DTOX RS01150
gene id: 485916:DTOX_RS01150
uniprot id: C8W3T0
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

485916:DTOX RS12170
gene id: 485916:DTOX_RS12170
uniprot id: C8W0N9
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS21045
gene id: 485916:DTOX_RS21045
uniprot id: C8W050
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

485916:DTOX RS03580
gene id: 485916:DTOX_RS03580
uniprot id: C8W1K4
names: Similarity
messages: Belongs to the GARS family.

485916:DTOX RS05730
gene id: 485916:DTOX_RS05730
uniprot id: C8W592
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS09510
gene id: 485916:DTOX_RS09510
uniprot id: C8VY93
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

485916:DTOX RS01395
gene id: 485916:DTOX_RS01395
uniprot id: C8W3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

485916:DTOX RS11370
gene id: 485916:DTOX_RS11370
uniprot id: C8W080
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS15610
gene id: 485916:DTOX_RS15610
uniprot id: C8W4S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

485916:DTOX RS15780
gene id: 485916:DTOX_RS15780
uniprot id: C8W5J1
names: Similarity
messages: Belongs to the GSP E family.

485916:DTOX RS13280
gene id: 485916:DTOX_RS13280
uniprot id: C8W1N6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS11690
gene id: 485916:DTOX_RS11690
uniprot id: C8W0E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

485916:DTOX RS19800
gene id: 485916:DTOX_RS19800
uniprot id: C8VYQ4
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS04385
gene id: 485916:DTOX_RS04385
uniprot id: C8W338
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

485916:DTOX RS11520
gene id: 485916:DTOX_RS11520
uniprot id: C8W0B0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

485916:DTOX RS05055
gene id: 485916:DTOX_RS05055
uniprot id: C8W473
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS15545
gene id: 485916:DTOX_RS15545
uniprot id: C8W4R0
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

485916:DTOX RS14400
gene id: 485916:DTOX_RS14400
uniprot id: C8W2P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

485916:DTOX RS11230
gene id: 485916:DTOX_RS11230
uniprot id: C8VZX9
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

485916:DTOX RS03855
gene id: 485916:DTOX_RS03855
uniprot id: C8W238
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS13250
gene id: 485916:DTOX_RS13250
uniprot id: C8W1N0
names: Similarity
messages: Belongs to the universal stress protein A family.

485916:DTOX RS01280
gene id: 485916:DTOX_RS01280
uniprot id: C8W3V1
names: Similarity
messages: Belongs to the CtsR family.

485916:DTOX RS07580
gene id: 485916:DTOX_RS07580
uniprot id: C8VW62
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

485916:DTOX RS11260
gene id: 485916:DTOX_RS11260
uniprot id: C8VZY5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

485916:DTOX RS11135
gene id: 485916:DTOX_RS11135
uniprot id: C8VZW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

485916:DTOX RS15355
gene id: 485916:DTOX_RS15355
uniprot id: C8W4M2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS17445
gene id: 485916:DTOX_RS17445
uniprot id: C8VW19
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

485916:DTOX RS05605
gene id: 485916:DTOX_RS05605
uniprot id: C8W567
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

485916:DTOX RS05775
gene id: 485916:DTOX_RS05775
uniprot id: C8W5A1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

485916:DTOX RS06865
gene id: 485916:DTOX_RS06865
uniprot id: C8VVH2
names: Similarity
messages: Belongs to the UPF0758 family.

485916:DTOX RS13845
gene id: 485916:DTOX_RS13845
uniprot id: C8W2D4
names: Similarity
messages: Belongs to the FemABX family.

485916:DTOX RS19700
gene id: 485916:DTOX_RS19700
uniprot id: C8VYN4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

485916:DTOX RS17335
gene id: 485916:DTOX_RS17335
uniprot id: C8VVZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

485916:DTOX RS08040
gene id: 485916:DTOX_RS08040
uniprot id: C8VWE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

485916:DTOX RS14765
gene id: 485916:DTOX_RS14765
uniprot id: C8W3L0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

485916:DTOX RS07705
gene id: 485916:DTOX_RS07705
uniprot id: C8VW84
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS10405
gene id: 485916:DTOX_RS10405
uniprot id: C8VZ32
names: Similarity
messages: Belongs to the UPF0735 family.

485916:DTOX RS15075
gene id: 485916:DTOX_RS15075
uniprot id: C8W3S2
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

485916:DTOX RS13945
gene id: 485916:DTOX_RS13945
uniprot id: C8W2F4
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS15560
gene id: 485916:DTOX_RS15560
uniprot id: C8W4R3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

485916:DTOX RS00355
gene id: 485916:DTOX_RS00355
uniprot id: C8VVG7
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

485916:DTOX RS11620
gene id: 485916:DTOX_RS11620
uniprot id: C8W0D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

485916:DTOX RS11415
gene id: 485916:DTOX_RS11415
uniprot id: C8W089
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

485916:DTOX RS00010
gene id: 485916:DTOX_RS00010
uniprot id: C8VV98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

485916:DTOX RS07835
gene id: 485916:DTOX_RS07835
uniprot id: C8VWB0
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

485916:DTOX RS18245
gene id: 485916:DTOX_RS18245
uniprot id: C8VX71
names: Similarity
messages: Belongs to the glutamine synthetase family.

485916:DTOX RS03035
gene id: 485916:DTOX_RS03035
uniprot id: C8W0W8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

485916:DTOX RS01405
gene id: 485916:DTOX_RS01405
uniprot id: C8W3X2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

485916:DTOX RS00275
gene id: 485916:DTOX_RS00275
uniprot id: C8VVE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

485916:DTOX RS10320
gene id: 485916:DTOX_RS10320
uniprot id: C8VZ14
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

485916:DTOX RS03560
gene id: 485916:DTOX_RS03560
uniprot id: C8W1K0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

485916:DTOX RS15085
gene id: 485916:DTOX_RS15085
uniprot id: C8W4H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

485916:DTOX RS00840
gene id: 485916:DTOX_RS00840
uniprot id: C8W2W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

485916:DTOX RS06835
gene id: 485916:DTOX_RS06835
uniprot id: C8W6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

485916:DTOX RS14500
gene id: 485916:DTOX_RS14500
uniprot id: C8W3G1
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

485916:DTOX RS08840
gene id: 485916:DTOX_RS08840
uniprot id: C8VXK3
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

485916:DTOX RS01490
gene id: 485916:DTOX_RS01490
uniprot id: C8W3Y9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

485916:DTOX RS21020
gene id: 485916:DTOX_RS21020
uniprot id: C8W045
names: Similarity
messages: Belongs to the peptidase S16 family.

485916:DTOX RS09815
gene id: 485916:DTOX_RS09815
uniprot id: C8VYE7
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS14645
gene id: 485916:DTOX_RS14645
uniprot id: C8W3I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

485916:DTOX RS15430
gene id: 485916:DTOX_RS15430
uniprot id: C8W4N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

485916:DTOX RS07745
gene id: 485916:DTOX_RS07745
uniprot id: C8VW92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485916:DTOX RS13495
gene id: 485916:DTOX_RS13495
uniprot id: C8W1S9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS19870
gene id: 485916:DTOX_RS19870
uniprot id: C8VYR9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

485916:DTOX RS01535
gene id: 485916:DTOX_RS01535
uniprot id: C8W3Z8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

485916:DTOX RS09800
gene id: 485916:DTOX_RS09800
uniprot id: C8VYE3
names: Similarity
messages: Belongs to the citrate synthase family.

485916:DTOX RS15510
gene id: 485916:DTOX_RS15510
uniprot id: C8W4Q3
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS20900
gene id: 485916:DTOX_RS20900
uniprot id: C8W027
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

485916:DTOX RS16460
gene id: 485916:DTOX_RS16460
uniprot id: C8W6L5
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS14510
gene id: 485916:DTOX_RS14510
uniprot id: C8W3G3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

485916:DTOX RS11500
gene id: 485916:DTOX_RS11500
uniprot id: C8W0A6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

485916:DTOX RS03940
gene id: 485916:DTOX_RS03940
uniprot id: C8W256
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

485916:DTOX RS16825
gene id: 485916:DTOX_RS16825
uniprot id: C8W6T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

485916:DTOX RS16175
gene id: 485916:DTOX_RS16175
uniprot id: C8W5R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

485916:DTOX RS20905
gene id: 485916:DTOX_RS20905
uniprot id: C8W028
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

485916:DTOX RS13595
gene id: 485916:DTOX_RS13595
uniprot id: C8W1U6
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS07925
gene id: 485916:DTOX_RS07925
uniprot id: C8VWC6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

485916:DTOX RS21105
gene id: 485916:DTOX_RS21105
uniprot id: C8W062
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

485916:DTOX RS07315
gene id: 485916:DTOX_RS07315
uniprot id: C8VVP8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

485916:DTOX RS19955
gene id: 485916:DTOX_RS19955
uniprot id: C8VYT5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

485916:DTOX RS05535
gene id: 485916:DTOX_RS05535
uniprot id: C8W4G7
names: Subcellular Location Annotation
messages: Membrane

485916:DTOX RS05610
gene id: 485916:DTOX_RS05610
uniprot id: C8W568
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

485916:DTOX RS21075
gene id: 485916:DTOX_RS21075
uniprot id: C8W056
names: Similarity
messages: Belongs to the ParB family.

485916:DTOX RS18180
gene id: 485916:DTOX_RS18180
uniprot id: C8VWT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

485916:DTOX RS15050
gene id: 485916:DTOX_RS15050
uniprot id: C8W3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

485916:DTOX RS03945
gene id: 485916:DTOX_RS03945
uniprot id: C8W257
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

485916:DTOX RS21630
gene id: 485916:DTOX_RS21630
uniprot id: C8W4M9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

485916:DTOX RS21110
gene id: 485916:DTOX_RS21110
uniprot id: C8W064
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

485916:DTOX RS01040
gene id: 485916:DTOX_RS01040
uniprot id: C8W305
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

485916:DTOX RS03985
gene id: 485916:DTOX_RS03985
uniprot id: C8W265
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

485916:DTOX RS20105
gene id: 485916:DTOX_RS20105
uniprot id: C8VZ90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

485916:DTOX RS14650
gene id: 485916:DTOX_RS14650
uniprot id: C8W3J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

485916:DTOX RS04510
gene id: 485916:DTOX_RS04510
uniprot id: C8W363
names: Similarity
messages: Belongs to the leucine-binding protein family.

485916:DTOX RS03015
gene id: 485916:DTOX_RS03015
uniprot id: C8W0W4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

485916:DTOX RS17055
gene id: 485916:DTOX_RS17055
uniprot id: C8VVU9
names: Similarity
messages: Belongs to the thioesterase PaaI family.

485916:DTOX RS05735
gene id: 485916:DTOX_RS05735
uniprot id: C8W593
names: Similarity
messages: Belongs to the peptidase C56 family.

485916:DTOX RS01195
gene id: 485916:DTOX_RS01195
uniprot id: C8W3T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

485916:DTOX RS03425
gene id: 485916:DTOX_RS03425
uniprot id: C8W1H3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

485916:DTOX RS09595
gene id: 485916:DTOX_RS09595
uniprot id: C8VYB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

485916:DTOX RS09910
gene id: 485916:DTOX_RS09910
uniprot id: C8VYG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

485916:DTOX RS02030
gene id: 485916:DTOX_RS02030
uniprot id: C8W4Z5
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

485916:DTOX RS04205
gene id: 485916:DTOX_RS04205
uniprot id: C8W2A6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485916:DTOX RS10975
gene id: 485916:DTOX_RS10975
uniprot id: C8VZS7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

485916:DTOX RS16375
gene id: 485916:DTOX_RS16375
uniprot id: C8W6J9
names: Similarity
messages: Belongs to the HdrA family.

485916:DTOX RS08255
gene id: 485916:DTOX_RS08255
uniprot id: C8VWW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

485916:DTOX RS09515
gene id: 485916:DTOX_RS09515
uniprot id: C8VY94
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

485916:DTOX RS10515
gene id: 485916:DTOX_RS10515
uniprot id: C8VZ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

485916:DTOX RS18150
gene id: 485916:DTOX_RS18150
uniprot id: C8VWT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

485916:DTOX RS20625
gene id: 485916:DTOX_RS20625
uniprot id: C8VZJ8
names: Similarity
messages: Belongs to the ETF-QO/FixC family.