485915:DRET RS10995
gene id: 485915:DRET_RS10995
uniprot id: C8X4Y4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

485915:DRET RS06870
gene id: 485915:DRET_RS06870
uniprot id: C8X2L7
names: Similarity
messages: Belongs to the glutamate synthase family.

485915:DRET RS10315
gene id: 485915:DRET_RS10315
uniprot id: C8X478
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

485915:DRET RS07030
gene id: 485915:DRET_RS07030
uniprot id: C8X2P7
names: Function
names: Similarity
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.

485915:DRET RS03275
gene id: 485915:DRET_RS03275
uniprot id: C8X0K0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

485915:DRET RS02235
gene id: 485915:DRET_RS02235
uniprot id: C8X0C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS08265
gene id: 485915:DRET_RS08265
uniprot id: C8X3E7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS08750
gene id: 485915:DRET_RS08750
uniprot id: C8X3N3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

485915:DRET RS00070
gene id: 485915:DRET_RS00070
uniprot id: C8WZ40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS09585
gene id: 485915:DRET_RS09585
uniprot id: C8X4I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

485915:DRET RS06970
gene id: 485915:DRET_RS06970
uniprot id: C8X2N5
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

485915:DRET RS08625
gene id: 485915:DRET_RS08625
uniprot id: C8X3L2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

485915:DRET RS00945
gene id: 485915:DRET_RS00945
uniprot id: C8WZL7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS08335
gene id: 485915:DRET_RS08335
uniprot id: C8X3G1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

485915:DRET RS05515
gene id: 485915:DRET_RS05515
uniprot id: C8X265
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS05665
gene id: 485915:DRET_RS05665
uniprot id: C8X295
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

485915:DRET RS10925
gene id: 485915:DRET_RS10925
uniprot id: C8X4W8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

485915:DRET RS03685
gene id: 485915:DRET_RS03685
uniprot id: C8X0T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

485915:DRET RS09380
gene id: 485915:DRET_RS09380
uniprot id: C8X412
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

485915:DRET RS02950
gene id: 485915:DRET_RS02950
uniprot id: C8WYW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

485915:DRET RS10270
gene id: 485915:DRET_RS10270
uniprot id: C8X469
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

485915:DRET RS10005
gene id: 485915:DRET_RS10005
uniprot id: C8X4R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

485915:DRET RS00690
gene id: 485915:DRET_RS00690
uniprot id: C8WZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

485915:DRET RS02905
gene id: 485915:DRET_RS02905
uniprot id: C8WYW0
names: Similarity
messages: Belongs to the MotB family.

485915:DRET RS02355
gene id: 485915:DRET_RS02355
uniprot id: C8X0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

485915:DRET RS07275
gene id: 485915:DRET_RS07275
uniprot id: C8X2U5
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS10305
gene id: 485915:DRET_RS10305
uniprot id: C8X476
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

485915:DRET RS00910
gene id: 485915:DRET_RS00910
uniprot id: C8WZK9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

485915:DRET RS07055
gene id: 485915:DRET_RS07055
uniprot id: C8X2Q2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

485915:DRET RS10555
gene id: 485915:DRET_RS10555
uniprot id: C8X4C0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

485915:DRET RS01525
gene id: 485915:DRET_RS01525
uniprot id: C8WZY3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

485915:DRET RS08630
gene id: 485915:DRET_RS08630
uniprot id: C8X3L3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

485915:DRET RS12055
gene id: 485915:DRET_RS12055
uniprot id: C8X5J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

485915:DRET RS09145
gene id: 485915:DRET_RS09145
uniprot id: C8X3W5
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

485915:DRET RS11630
gene id: 485915:DRET_RS11630
uniprot id: C8X5A8
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS05775
gene id: 485915:DRET_RS05775
uniprot id: C8X1L7
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

485915:DRET RS09535
gene id: 485915:DRET_RS09535
uniprot id: C8X4H1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS08145
gene id: 485915:DRET_RS08145
uniprot id: C8X3C3
names: Subunit
messages: Homodimer.

485915:DRET RS05140
gene id: 485915:DRET_RS05140
uniprot id: C8X1Z0
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS11325
gene id: 485915:DRET_RS11325
uniprot id: C8X548
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

485915:DRET RS08075
gene id: 485915:DRET_RS08075
uniprot id: C8X3A9
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

485915:DRET RS10310
gene id: 485915:DRET_RS10310
uniprot id: C8X477
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

485915:DRET RS00050
gene id: 485915:DRET_RS00050
uniprot id: C8WZ36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS11120
gene id: 485915:DRET_RS11120
uniprot id: C8X509
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS12780
gene id: 485915:DRET_RS12780
uniprot id: C8WZC3
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS07395
gene id: 485915:DRET_RS07395
uniprot id: C8X2X0
names: Similarity
messages: Belongs to the DEAD box helicase family.

485915:DRET RS03820
gene id: 485915:DRET_RS03820
uniprot id: C8X0V6
names: Similarity
messages: Belongs to the peptidase M18 family.

485915:DRET RS00895
gene id: 485915:DRET_RS00895
uniprot id: C8WZK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

485915:DRET RS01340
gene id: 485915:DRET_RS01340
uniprot id: C8WZU5
names: Similarity
messages: Belongs to the HupF/HypC family.

485915:DRET RS05600
gene id: 485915:DRET_RS05600
uniprot id: C8X282
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

485915:DRET RS11030
gene id: 485915:DRET_RS11030
uniprot id: C8X4Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

485915:DRET RS06630
gene id: 485915:DRET_RS06630
uniprot id: C8X2G6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

485915:DRET RS00430
gene id: 485915:DRET_RS00430
uniprot id: C8WZB2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

485915:DRET RS02515
gene id: 485915:DRET_RS02515
uniprot id: C8X0H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

485915:DRET RS03740
gene id: 485915:DRET_RS03740
uniprot id: C8X0U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS01345
gene id: 485915:DRET_RS01345
uniprot id: C8WZU6
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

485915:DRET RS11440
gene id: 485915:DRET_RS11440
uniprot id: C8X570
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

485915:DRET RS03790
gene id: 485915:DRET_RS03790
uniprot id: C8X0V1
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS10325
gene id: 485915:DRET_RS10325
uniprot id: C8X480
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

485915:DRET RS09360
gene id: 485915:DRET_RS09360
uniprot id: C8X407
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

485915:DRET RS02465
gene id: 485915:DRET_RS02465
uniprot id: C8X0G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

485915:DRET RS04360
gene id: 485915:DRET_RS04360
uniprot id: C8X158
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

485915:DRET RS02650
gene id: 485915:DRET_RS02650
uniprot id: C8WYR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

485915:DRET RS07335
gene id: 485915:DRET_RS07335
uniprot id: C8X2V7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

485915:DRET RS06980
gene id: 485915:DRET_RS06980
uniprot id: C8X2N7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

485915:DRET RS08500
gene id: 485915:DRET_RS08500
uniprot id: C8X3J3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

485915:DRET RS04530
gene id: 485915:DRET_RS04530
uniprot id: C8X193
names: Similarity
messages: Belongs to the peptidase S24 family.

485915:DRET RS03760
gene id: 485915:DRET_RS03760
uniprot id: C8X0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

485915:DRET RS02815
gene id: 485915:DRET_RS02815
uniprot id: C8WYU3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

485915:DRET RS09635
gene id: 485915:DRET_RS09635
uniprot id: C8X4J1
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

485915:DRET RS01530
gene id: 485915:DRET_RS01530
uniprot id: C8WZY4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

485915:DRET RS01145
gene id: 485915:DRET_RS01145
uniprot id: C8WZQ6
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS09705
gene id: 485915:DRET_RS09705
uniprot id: C8X4K4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS03405
gene id: 485915:DRET_RS03405
uniprot id: C8X0M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

485915:DRET RS02495
gene id: 485915:DRET_RS02495
uniprot id: C8X0H4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

485915:DRET RS09480
gene id: 485915:DRET_RS09480
uniprot id: C8X4F9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

485915:DRET RS02420
gene id: 485915:DRET_RS02420
uniprot id: C8X0F9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

485915:DRET RS10990
gene id: 485915:DRET_RS10990
uniprot id: C8X4Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

485915:DRET RS09470
gene id: 485915:DRET_RS09470
uniprot id: C8X4F6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

485915:DRET RS12965
gene id: 485915:DRET_RS12965
uniprot id: C8X1Y2
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

485915:DRET RS00235
gene id: 485915:DRET_RS00235
uniprot id: C8WZ74
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

485915:DRET RS07990
gene id: 485915:DRET_RS07990
uniprot id: C8X394
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS06825
gene id: 485915:DRET_RS06825
uniprot id: C8X2K7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

485915:DRET RS12455
gene id: 485915:DRET_RS12455
uniprot id: C8X5S0
names: Similarity
messages: Belongs to the IMPACT family.

485915:DRET RS10700
gene id: 485915:DRET_RS10700
uniprot id: C8X4E8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS06690
gene id: 485915:DRET_RS06690
uniprot id: C8X2H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

485915:DRET RS04015
gene id: 485915:DRET_RS04015
uniprot id: C8X0Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

485915:DRET RS04265
gene id: 485915:DRET_RS04265
uniprot id: C8X137
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS08915
gene id: 485915:DRET_RS08915
uniprot id: C8X3R7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

485915:DRET RS02370
gene id: 485915:DRET_RS02370
uniprot id: C8X0E9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

485915:DRET RS00790
gene id: 485915:DRET_RS00790
uniprot id: C8WZI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

485915:DRET RS07185
gene id: 485915:DRET_RS07185
uniprot id: C8X2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

485915:DRET RS00075
gene id: 485915:DRET_RS00075
uniprot id: C8WZ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS01470
gene id: 485915:DRET_RS01470
uniprot id: C8WZX2
names: Similarity
messages: Belongs to the RemA family.

485915:DRET RS07365
gene id: 485915:DRET_RS07365
uniprot id: C8X2W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

485915:DRET RS06800
gene id: 485915:DRET_RS06800
uniprot id: C8X2K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485915:DRET RS00855
gene id: 485915:DRET_RS00855
uniprot id: C8WZJ8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

485915:DRET RS07770
gene id: 485915:DRET_RS07770
uniprot id: C8X349
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

485915:DRET RS01575
gene id: 485915:DRET_RS01575
uniprot id: C8WZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

485915:DRET RS10290
gene id: 485915:DRET_RS10290
uniprot id: C8X473
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

485915:DRET RS12220
gene id: 485915:DRET_RS12220
uniprot id: C8X5M6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

485915:DRET RS10980
gene id: 485915:DRET_RS10980
uniprot id: C8X4Y1
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS10915
gene id: 485915:DRET_RS10915
uniprot id: C8X4W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS11315
gene id: 485915:DRET_RS11315
uniprot id: C8X547
names: Similarity
messages: Belongs to the HdrA family.

485915:DRET RS01170
gene id: 485915:DRET_RS01170
uniprot id: C8WZR2
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS07110
gene id: 485915:DRET_RS07110
uniprot id: C8X2R2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS05535
gene id: 485915:DRET_RS05535
uniprot id: C8X269
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

485915:DRET RS03735
gene id: 485915:DRET_RS03735
uniprot id: C8X0U0
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS05525
gene id: 485915:DRET_RS05525
uniprot id: C8X267
names: Similarity
messages: Belongs to the Nudix hydrolase family.

485915:DRET RS02720
gene id: 485915:DRET_RS02720
uniprot id: C8WYS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

485915:DRET RS00080
gene id: 485915:DRET_RS00080
uniprot id: C8WZ42
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

485915:DRET RS10735
gene id: 485915:DRET_RS10735
uniprot id: C8X4T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

485915:DRET RS10865
gene id: 485915:DRET_RS10865
uniprot id: C8X4W1
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS02980
gene id: 485915:DRET_RS02980
uniprot id: C8WYX5
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

485915:DRET RS10175
gene id: 485915:DRET_RS10175
uniprot id: C8X448
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

485915:DRET RS05610
gene id: 485915:DRET_RS05610
uniprot id: C8X284
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

485915:DRET RS00240
gene id: 485915:DRET_RS00240
uniprot id: C8WZ75
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

485915:DRET RS07560
gene id: 485915:DRET_RS07560
uniprot id: C8X303
names: Similarity
messages: Belongs to the CvfB family.

485915:DRET RS10020
gene id: 485915:DRET_RS10020
uniprot id: C8X4R8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

485915:DRET RS11195
gene id: 485915:DRET_RS11195
uniprot id: C8X523
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

485915:DRET RS05595
gene id: 485915:DRET_RS05595
uniprot id: C8X281
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

485915:DRET RS04300
gene id: 485915:DRET_RS04300
uniprot id: C8X145
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

485915:DRET RS09160
gene id: 485915:DRET_RS09160
uniprot id: C8X3W8
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS09240
gene id: 485915:DRET_RS09240
uniprot id: C8X3Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

485915:DRET RS01645
gene id: 485915:DRET_RS01645
uniprot id: C8X008
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

485915:DRET RS09140
gene id: 485915:DRET_RS09140
uniprot id: C8X3W4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

485915:DRET RS03030
gene id: 485915:DRET_RS03030
uniprot id: C8WYY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

485915:DRET RS09195
gene id: 485915:DRET_RS09195
uniprot id: C8X3X5
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS02050
gene id: 485915:DRET_RS02050
uniprot id: C8X087
names: Similarity
messages: Belongs to the universal stress protein A family.

485915:DRET RS10320
gene id: 485915:DRET_RS10320
uniprot id: C8X479
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

485915:DRET RS10380
gene id: 485915:DRET_RS10380
uniprot id: C8X477
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

485915:DRET RS10185
gene id: 485915:DRET_RS10185
uniprot id: C8X450
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

485915:DRET RS10760
gene id: 485915:DRET_RS10760
uniprot id: C8X4U0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

485915:DRET RS05700
gene id: 485915:DRET_RS05700
uniprot id: C8X2A2
names: Similarity
messages: Belongs to the leucine-binding protein family.

485915:DRET RS12380
gene id: 485915:DRET_RS12380
uniprot id: C8X5Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

485915:DRET RS04600
gene id: 485915:DRET_RS04600
uniprot id: C8X1A7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

485915:DRET RS11520
gene id: 485915:DRET_RS11520
uniprot id: C8X587
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

485915:DRET RS04595
gene id: 485915:DRET_RS04595
uniprot id: C8X1A6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

485915:DRET RS04610
gene id: 485915:DRET_RS04610
uniprot id: C8X1A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

485915:DRET RS09350
gene id: 485915:DRET_RS09350
uniprot id: C8X405
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

485915:DRET RS06295
gene id: 485915:DRET_RS06295
uniprot id: C8X1X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

485915:DRET RS02675
gene id: 485915:DRET_RS02675
uniprot id: C8WYR8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

485915:DRET RS08365
gene id: 485915:DRET_RS08365
uniprot id: C8X3G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

485915:DRET RS06545
gene id: 485915:DRET_RS06545
uniprot id: C8X2E8
names: Similarity
messages: Belongs to the leucine-binding protein family.

485915:DRET RS02255
gene id: 485915:DRET_RS02255
uniprot id: C8X0C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

485915:DRET RS09430
gene id: 485915:DRET_RS09430
uniprot id: C8X422
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

485915:DRET RS11270
gene id: 485915:DRET_RS11270
uniprot id: C8X538
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

485915:DRET RS02080
gene id: 485915:DRET_RS02080
uniprot id: C8X093
names: Similarity
messages: Belongs to the HdrA family.

485915:DRET RS04880
gene id: 485915:DRET_RS04880
uniprot id: C8X1G4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

485915:DRET RS11720
gene id: 485915:DRET_RS11720
uniprot id: C8X5C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

485915:DRET RS11910
gene id: 485915:DRET_RS11910
uniprot id: C8X5G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

485915:DRET RS06945
gene id: 485915:DRET_RS06945
uniprot id: C8X2N0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

485915:DRET RS01510
gene id: 485915:DRET_RS01510
uniprot id: C8WZY0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

485915:DRET RS10015
gene id: 485915:DRET_RS10015
uniprot id: C8X4R7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

485915:DRET RS05230
gene id: 485915:DRET_RS05230
uniprot id: C8X209
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485915:DRET RS04240
gene id: 485915:DRET_RS04240
uniprot id: C8X133
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

485915:DRET RS06645
gene id: 485915:DRET_RS06645
uniprot id: C8X2G9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

485915:DRET RS04845
gene id: 485915:DRET_RS04845
uniprot id: C8X1F6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS02620
gene id: 485915:DRET_RS02620
uniprot id: C8WYQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

485915:DRET RS05895
gene id: 485915:DRET_RS05895
uniprot id: C8X1K6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

485915:DRET RS00570
gene id: 485915:DRET_RS00570
uniprot id: C8WZE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

485915:DRET RS02975
gene id: 485915:DRET_RS02975
uniprot id: C8WYX4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

485915:DRET RS09375
gene id: 485915:DRET_RS09375
uniprot id: C8X411
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

485915:DRET RS10115
gene id: 485915:DRET_RS10115
uniprot id: C8X436
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

485915:DRET RS10230
gene id: 485915:DRET_RS10230
uniprot id: C8X460
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

485915:DRET RS06650
gene id: 485915:DRET_RS06650
uniprot id: C8X2H0
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS05355
gene id: 485915:DRET_RS05355
uniprot id: C8X233
names: Similarity
messages: Belongs to the class-I fumarase family.

485915:DRET RS10265
gene id: 485915:DRET_RS10265
uniprot id: C8X468
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

485915:DRET RS01475
gene id: 485915:DRET_RS01475
uniprot id: C8WZX3
names: Similarity
messages: Belongs to the YicC/YloC family.

485915:DRET RS06540
gene id: 485915:DRET_RS06540
uniprot id: C8X2E7
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS10670
gene id: 485915:DRET_RS10670
uniprot id: C8X4E2
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS04275
gene id: 485915:DRET_RS04275
uniprot id: C8X139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

485915:DRET RS10250
gene id: 485915:DRET_RS10250
uniprot id: C8X465
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

485915:DRET RS11905
gene id: 485915:DRET_RS11905
uniprot id: C8X5G4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

485915:DRET RS01365
gene id: 485915:DRET_RS01365
uniprot id: C8WZV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

485915:DRET RS08850
gene id: 485915:DRET_RS08850
uniprot id: C8X3Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

485915:DRET RS10080
gene id: 485915:DRET_RS10080
uniprot id: C8X4T0
names: Similarity
messages: Belongs to the UPF0102 family.

485915:DRET RS10285
gene id: 485915:DRET_RS10285
uniprot id: C8X472
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

485915:DRET RS05290
gene id: 485915:DRET_RS05290
uniprot id: C8X220
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS11180
gene id: 485915:DRET_RS11180
uniprot id: C8X521
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS02910
gene id: 485915:DRET_RS02910
uniprot id: C8WYW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

485915:DRET RS01570
gene id: 485915:DRET_RS01570
uniprot id: C8WZZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS07955
gene id: 485915:DRET_RS07955
uniprot id: C8X387
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

485915:DRET RS05385
gene id: 485915:DRET_RS05385
uniprot id: C8X239
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

485915:DRET RS06795
gene id: 485915:DRET_RS06795
uniprot id: C8X2K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485915:DRET RS07045
gene id: 485915:DRET_RS07045
uniprot id: C8X2Q0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

485915:DRET RS12110
gene id: 485915:DRET_RS12110
uniprot id: C8X5K5
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

485915:DRET RS10360
gene id: 485915:DRET_RS10360
uniprot id: C8X487
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

485915:DRET RS07980
gene id: 485915:DRET_RS07980
uniprot id: C8X392
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

485915:DRET RS05870
gene id: 485915:DRET_RS05870
uniprot id: C8X1N6
names: Similarity
messages: Belongs to the peptidase A24 family.

485915:DRET RS02730
gene id: 485915:DRET_RS02730
uniprot id: C8WYS8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485915:DRET RS05740
gene id: 485915:DRET_RS05740
uniprot id: C8X2B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane

485915:DRET RS08840
gene id: 485915:DRET_RS08840
uniprot id: C8X3Q1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

485915:DRET RS03890
gene id: 485915:DRET_RS03890
uniprot id: C8X0W8
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

485915:DRET RS09020
gene id: 485915:DRET_RS09020
uniprot id: C8X3T9
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

485915:DRET RS09175
gene id: 485915:DRET_RS09175
uniprot id: C8X3X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

485915:DRET RS10365
gene id: 485915:DRET_RS10365
uniprot id: C8X488
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

485915:DRET RS12790
gene id: 485915:DRET_RS12790
uniprot id: C8WZH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

485915:DRET RS11355
gene id: 485915:DRET_RS11355
uniprot id: C8X554
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

485915:DRET RS10405
gene id: 485915:DRET_RS10405
uniprot id: C8X491
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

485915:DRET RS08880
gene id: 485915:DRET_RS08880
uniprot id: C8X3R0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

485915:DRET RS06345
gene id: 485915:DRET_RS06345
uniprot id: C8X1Y5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

485915:DRET RS02225
gene id: 485915:DRET_RS02225
uniprot id: C8X0C1
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

485915:DRET RS08655
gene id: 485915:DRET_RS08655
uniprot id: C8X3L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

485915:DRET RS07070
gene id: 485915:DRET_RS07070
uniprot id: C8X2Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

485915:DRET RS00155
gene id: 485915:DRET_RS00155
uniprot id: C8WZ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

485915:DRET RS09050
gene id: 485915:DRET_RS09050
uniprot id: C8X3U5
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

485915:DRET RS10550
gene id: 485915:DRET_RS10550
uniprot id: C8X4B9
names: Similarity
messages: Belongs to the UPF0047 family.

485915:DRET RS01455
gene id: 485915:DRET_RS01455
uniprot id: C8WZW9
names: Similarity
messages: Belongs to the RecJ family.

485915:DRET RS12170
gene id: 485915:DRET_RS12170
uniprot id: C8X5L7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

485915:DRET RS09570
gene id: 485915:DRET_RS09570
uniprot id: C8X4H8
names: Similarity
messages: Belongs to the GSP E family.

485915:DRET RS08420
gene id: 485915:DRET_RS08420
uniprot id: C8X3H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

485915:DRET RS05500
gene id: 485915:DRET_RS05500
uniprot id: C8X262
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

485915:DRET RS03815
gene id: 485915:DRET_RS03815
uniprot id: C8X0V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

485915:DRET RS04955
gene id: 485915:DRET_RS04955
uniprot id: C8X1H9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

485915:DRET RS07295
gene id: 485915:DRET_RS07295
uniprot id: C8X2U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

485915:DRET RS07815
gene id: 485915:DRET_RS07815
uniprot id: C8X359
names: Similarity
messages: Belongs to the UDPGP type 1 family.

485915:DRET RS02360
gene id: 485915:DRET_RS02360
uniprot id: C8X0E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485915:DRET RS06215
gene id: 485915:DRET_RS06215
uniprot id: C8X1W0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS08930
gene id: 485915:DRET_RS08930
uniprot id: C8X3S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

485915:DRET RS09495
gene id: 485915:DRET_RS09495
uniprot id: C8X4G3
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

485915:DRET RS03955
gene id: 485915:DRET_RS03955
uniprot id: C8X0Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

485915:DRET RS06600
gene id: 485915:DRET_RS06600
uniprot id: C8X2F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

485915:DRET RS10170
gene id: 485915:DRET_RS10170
uniprot id: C8X447
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

485915:DRET RS08380
gene id: 485915:DRET_RS08380
uniprot id: C8X3H0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

485915:DRET RS09745
gene id: 485915:DRET_RS09745
uniprot id: C8X4L2
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS10130
gene id: 485915:DRET_RS10130
uniprot id: C8X439
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

485915:DRET RS04330
gene id: 485915:DRET_RS04330
uniprot id: C8X152
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

485915:DRET RS05420
gene id: 485915:DRET_RS05420
uniprot id: C8X246
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

485915:DRET RS03915
gene id: 485915:DRET_RS03915
uniprot id: C8X0X3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

485915:DRET RS09725
gene id: 485915:DRET_RS09725
uniprot id: C8X4K8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS02525
gene id: 485915:DRET_RS02525
uniprot id: C8X0I0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

485915:DRET RS03440
gene id: 485915:DRET_RS03440
uniprot id: C8X0N3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

485915:DRET RS10690
gene id: 485915:DRET_RS10690
uniprot id: C8X4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

485915:DRET RS04850
gene id: 485915:DRET_RS04850
uniprot id: C8X1F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

485915:DRET RS02375
gene id: 485915:DRET_RS02375
uniprot id: C8X0F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485915:DRET RS03135
gene id: 485915:DRET_RS03135
uniprot id: C8WZ05
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

485915:DRET RS03355
gene id: 485915:DRET_RS03355
uniprot id: C8X0L6
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

485915:DRET RS08160
gene id: 485915:DRET_RS08160
uniprot id: C8X3C6
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS05015
gene id: 485915:DRET_RS05015
uniprot id: C8X1J1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

485915:DRET RS04920
gene id: 485915:DRET_RS04920
uniprot id: C8X1H1
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS06005
gene id: 485915:DRET_RS06005
uniprot id: C8X1R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Belongs to the universal stress protein A family.
messages: Membrane

485915:DRET RS05070
gene id: 485915:DRET_RS05070
uniprot id: C8X1K1
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

485915:DRET RS02990
gene id: 485915:DRET_RS02990
uniprot id: C8WYX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

485915:DRET RS13140
gene id: 485915:DRET_RS13140
uniprot id: C8X575
names: Similarity
messages: Belongs to the transglycosylase Slt family.

485915:DRET RS11360
gene id: 485915:DRET_RS11360
uniprot id: C8X555
names: Similarity
messages: Belongs to the P(II) protein family.

485915:DRET RS12035
gene id: 485915:DRET_RS12035
uniprot id: C8X5J0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

485915:DRET RS05185
gene id: 485915:DRET_RS05185
uniprot id: C8X200
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

485915:DRET RS10960
gene id: 485915:DRET_RS10960
uniprot id: C8X4X7
names: Similarity
messages: Belongs to the peptidase M16 family.

485915:DRET RS04550
gene id: 485915:DRET_RS04550
uniprot id: C8X197
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell inner membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

485915:DRET RS02155
gene id: 485915:DRET_RS02155
uniprot id: C8X0A6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

485915:DRET RS09130
gene id: 485915:DRET_RS09130
uniprot id: C8X3W2
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

485915:DRET RS03310
gene id: 485915:DRET_RS03310
uniprot id: C8X0K7
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

485915:DRET RS08785
gene id: 485915:DRET_RS08785
uniprot id: C8X3N9
names: Similarity
messages: Belongs to the DEAD box helicase family.

485915:DRET RS04785
gene id: 485915:DRET_RS04785
uniprot id: C8X1E4
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

485915:DRET RS10710
gene id: 485915:DRET_RS10710
uniprot id: C8X4F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

485915:DRET RS03060
gene id: 485915:DRET_RS03060
uniprot id: C8WYZ1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

485915:DRET RS11220
gene id: 485915:DRET_RS11220
uniprot id: C8X528
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS03265
gene id: 485915:DRET_RS03265
uniprot id: C8X0J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

485915:DRET RS06525
gene id: 485915:DRET_RS06525
uniprot id: C8X2E4
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

485915:DRET RS07285
gene id: 485915:DRET_RS07285
uniprot id: C8X2U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

485915:DRET RS10375
gene id: 485915:DRET_RS10375
uniprot id: C8X489
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

485915:DRET RS11350
gene id: 485915:DRET_RS11350
uniprot id: C8X553
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

485915:DRET RS04500
gene id: 485915:DRET_RS04500
uniprot id: C8X187
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

485915:DRET RS00755
gene id: 485915:DRET_RS00755
uniprot id: C8WZH6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

485915:DRET RS08715
gene id: 485915:DRET_RS08715
uniprot id: C8X3M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

485915:DRET RS10190
gene id: 485915:DRET_RS10190
uniprot id: C8X451
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

485915:DRET RS09640
gene id: 485915:DRET_RS09640
uniprot id: C8X4J2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

485915:DRET RS01515
gene id: 485915:DRET_RS01515
uniprot id: C8WZY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

485915:DRET RS06755
gene id: 485915:DRET_RS06755
uniprot id: C8X2J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

485915:DRET RS09150
gene id: 485915:DRET_RS09150
uniprot id: C8X3W6
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

485915:DRET RS02410
gene id: 485915:DRET_RS02410
uniprot id: C8X0F7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

485915:DRET RS10930
gene id: 485915:DRET_RS10930
uniprot id: C8X4W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

485915:DRET RS04895
gene id: 485915:DRET_RS04895
uniprot id: C8X1G6
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS12510
gene id: 485915:DRET_RS12510
uniprot id: C8X5T2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS00705
gene id: 485915:DRET_RS00705
uniprot id: C8WZG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

485915:DRET RS09505
gene id: 485915:DRET_RS09505
uniprot id: C8X4G5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

485915:DRET RS07445
gene id: 485915:DRET_RS07445
uniprot id: C8X2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

485915:DRET RS04525
gene id: 485915:DRET_RS04525
uniprot id: C8X192
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

485915:DRET RS06210
gene id: 485915:DRET_RS06210
uniprot id: C8X1V9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

485915:DRET RS00180
gene id: 485915:DRET_RS00180
uniprot id: C8WZ63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

485915:DRET RS01590
gene id: 485915:DRET_RS01590
uniprot id: C8WZZ7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS07860
gene id: 485915:DRET_RS07860
uniprot id: C8X368
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

485915:DRET RS09760
gene id: 485915:DRET_RS09760
uniprot id: C8X4L5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

485915:DRET RS04230
gene id: 485915:DRET_RS04230
uniprot id: C8X132
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

485915:DRET RS11385
gene id: 485915:DRET_RS11385
uniprot id: C8X560
names: Similarity
messages: Belongs to the ABC transporter superfamily.

485915:DRET RS11895
gene id: 485915:DRET_RS11895
uniprot id: C8X5G2
names: Similarity
messages: Belongs to the universal stress protein A family.

485915:DRET RS12695
gene id: 485915:DRET_RS12695
uniprot id: C8X5W7
names: Similarity
messages: Belongs to the ros/MucR family.

485915:DRET RS07760
gene id: 485915:DRET_RS07760
uniprot id: C8X346
names: Similarity
messages: Belongs to the GcvT family.

485915:DRET RS00860
gene id: 485915:DRET_RS00860
uniprot id: C8WZJ9
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS09220
gene id: 485915:DRET_RS09220
uniprot id: C8X3X9
names: Similarity
messages: Belongs to the AOR/FOR family.

485915:DRET RS00785
gene id: 485915:DRET_RS00785
uniprot id: C8WZI4
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

485915:DRET RS06595
gene id: 485915:DRET_RS06595
uniprot id: C8X2F8
names: Similarity
messages: Belongs to the fabD family.

485915:DRET RS04170
gene id: 485915:DRET_RS04170
uniprot id: C8X120
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

485915:DRET RS11645
gene id: 485915:DRET_RS11645
uniprot id: C8X5B1
names: Similarity
messages: Belongs to the UxaA family.

485915:DRET RS00185
gene id: 485915:DRET_RS00185
uniprot id: C8WZ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

485915:DRET RS08835
gene id: 485915:DRET_RS08835
uniprot id: C8X3P9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS11260
gene id: 485915:DRET_RS11260
uniprot id: C8X536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

485915:DRET RS00810
gene id: 485915:DRET_RS00810
uniprot id: C8WZI9
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS00365
gene id: 485915:DRET_RS00365
uniprot id: C8WZ99
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

485915:DRET RS00360
gene id: 485915:DRET_RS00360
uniprot id: C8WZ98
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS07415
gene id: 485915:DRET_RS07415
uniprot id: C8X2X3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

485915:DRET RS09625
gene id: 485915:DRET_RS09625
uniprot id: C8X4I9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

485915:DRET RS10030
gene id: 485915:DRET_RS10030
uniprot id: C8X4S0
names: Subunit
messages: Homodimer.

485915:DRET RS02260
gene id: 485915:DRET_RS02260
uniprot id: C8X0C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

485915:DRET RS11795
gene id: 485915:DRET_RS11795
uniprot id: C8X5E1
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS04245
gene id: 485915:DRET_RS04245
uniprot id: C8X134
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

485915:DRET RS06985
gene id: 485915:DRET_RS06985
uniprot id: C8X2N8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

485915:DRET RS04625
gene id: 485915:DRET_RS04625
uniprot id: C8X1B2
names: Subunit
messages: Heterodimer of a large and a small subunit.

485915:DRET RS02280
gene id: 485915:DRET_RS02280
uniprot id: C8X0D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

485915:DRET RS10220
gene id: 485915:DRET_RS10220
uniprot id: C8X458
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

485915:DRET RS08195
gene id: 485915:DRET_RS08195
uniprot id: C8X3D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

485915:DRET RS01940
gene id: 485915:DRET_RS01940
uniprot id: C8X069
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

485915:DRET RS02615
gene id: 485915:DRET_RS02615
uniprot id: C8WYQ6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

485915:DRET RS05450
gene id: 485915:DRET_RS05450
uniprot id: C8X252
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

485915:DRET RS05440
gene id: 485915:DRET_RS05440
uniprot id: C8X250
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

485915:DRET RS08000
gene id: 485915:DRET_RS08000
uniprot id: C8X396
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

485915:DRET RS05635
gene id: 485915:DRET_RS05635
uniprot id: C8X289
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS04220
gene id: 485915:DRET_RS04220
uniprot id: C8X130
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

485915:DRET RS00340
gene id: 485915:DRET_RS00340
uniprot id: C8WZ93
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

485915:DRET RS08815
gene id: 485915:DRET_RS08815
uniprot id: C8X3P5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

485915:DRET RS10105
gene id: 485915:DRET_RS10105
uniprot id: C8X434
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

485915:DRET RS01555
gene id: 485915:DRET_RS01555
uniprot id: C8WZY9
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

485915:DRET RS12210
gene id: 485915:DRET_RS12210
uniprot id: C8X5M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

485915:DRET RS01110
gene id: 485915:DRET_RS01110
uniprot id: C8WZQ0
names: Similarity
messages: Belongs to the histone deacetylase family.

485915:DRET RS01400
gene id: 485915:DRET_RS01400
uniprot id: C8WZV7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

485915:DRET RS01440
gene id: 485915:DRET_RS01440
uniprot id: C8WZW6
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS11160
gene id: 485915:DRET_RS11160
uniprot id: C8X517
names: Similarity
messages: Belongs to the Skp family.

485915:DRET RS09110
gene id: 485915:DRET_RS09110
uniprot id: C8X3V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

485915:DRET RS09465
gene id: 485915:DRET_RS09465
uniprot id: C8X431
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

485915:DRET RS11470
gene id: 485915:DRET_RS11470
uniprot id: C8X576
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

485915:DRET RS10685
gene id: 485915:DRET_RS10685
uniprot id: C8X4E5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

485915:DRET RS03585
gene id: 485915:DRET_RS03585
uniprot id: C8X0R3
names: Similarity
messages: Belongs to the UPF0434 family.

485915:DRET RS12310
gene id: 485915:DRET_RS12310
uniprot id: C8X5P0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS02265
gene id: 485915:DRET_RS02265
uniprot id: C8X0C8
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

485915:DRET RS11060
gene id: 485915:DRET_RS11060
uniprot id: C8X4Z7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS10340
gene id: 485915:DRET_RS10340
uniprot id: C8X483
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

485915:DRET RS08240
gene id: 485915:DRET_RS08240
uniprot id: C8X3E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

485915:DRET RS07375
gene id: 485915:DRET_RS07375
uniprot id: C8X2W5
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS08340
gene id: 485915:DRET_RS08340
uniprot id: C8X3G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

485915:DRET RS10465
gene id: 485915:DRET_RS10465
uniprot id: C8X4A2
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS07115
gene id: 485915:DRET_RS07115
uniprot id: C8X2R3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

485915:DRET RS08490
gene id: 485915:DRET_RS08490
uniprot id: C8X3J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

485915:DRET RS00525
gene id: 485915:DRET_RS00525
uniprot id: C8WZD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

485915:DRET RS11095
gene id: 485915:DRET_RS11095
uniprot id: C8X504
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

485915:DRET RS07530
gene id: 485915:DRET_RS07530
uniprot id: C8X2Z5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

485915:DRET RS01065
gene id: 485915:DRET_RS01065
uniprot id: C8WZP1
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS03715
gene id: 485915:DRET_RS03715
uniprot id: C8X0T6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS11150
gene id: 485915:DRET_RS11150
uniprot id: C8X515
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

485915:DRET RS04070
gene id: 485915:DRET_RS04070
uniprot id: C8X101
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

485915:DRET RS12085
gene id: 485915:DRET_RS12085
uniprot id: C8X5K0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

485915:DRET RS07060
gene id: 485915:DRET_RS07060
uniprot id: C8X2Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

485915:DRET RS09710
gene id: 485915:DRET_RS09710
uniprot id: C8X4K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

485915:DRET RS01370
gene id: 485915:DRET_RS01370
uniprot id: C8WZV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

485915:DRET RS10825
gene id: 485915:DRET_RS10825
uniprot id: C8X4V3
names: Similarity
messages: Belongs to the ros/MucR family.

485915:DRET RS01320
gene id: 485915:DRET_RS01320
uniprot id: C8WZU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

485915:DRET RS03680
gene id: 485915:DRET_RS03680
uniprot id: C8X0S9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

485915:DRET RS06175
gene id: 485915:DRET_RS06175
uniprot id: C8X1V2
names: Similarity
messages: Belongs to the catalase family.

485915:DRET RS00170
gene id: 485915:DRET_RS00170
uniprot id: C8WZ61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

485915:DRET RS02145
gene id: 485915:DRET_RS02145
uniprot id: C8X0A4
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS10565
gene id: 485915:DRET_RS10565
uniprot id: C8X4C2
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS04025
gene id: 485915:DRET_RS04025
uniprot id: C8X0Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

485915:DRET RS08435
gene id: 485915:DRET_RS08435
uniprot id: C8X3I0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

485915:DRET RS12155
gene id: 485915:DRET_RS12155
uniprot id: C8X5L4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

485915:DRET RS02630
gene id: 485915:DRET_RS02630
uniprot id: C8WYQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

485915:DRET RS00890
gene id: 485915:DRET_RS00890
uniprot id: C8WZK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

485915:DRET RS06590
gene id: 485915:DRET_RS06590
uniprot id: C8X2F7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

485915:DRET RS11065
gene id: 485915:DRET_RS11065
uniprot id: C8X4Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

485915:DRET RS01335
gene id: 485915:DRET_RS01335
uniprot id: C8WZU4
names: Similarity
messages: Belongs to the peptidase A31 family.

485915:DRET RS05000
gene id: 485915:DRET_RS05000
uniprot id: C8X1I8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

485915:DRET RS00955
gene id: 485915:DRET_RS00955
uniprot id: C8WZL9
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

485915:DRET RS02510
gene id: 485915:DRET_RS02510
uniprot id: C8X0H7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

485915:DRET RS03480
gene id: 485915:DRET_RS03480
uniprot id: C8X0P1
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

485915:DRET RS10180
gene id: 485915:DRET_RS10180
uniprot id: C8X449
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

485915:DRET RS03870
gene id: 485915:DRET_RS03870
uniprot id: C8X0W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

485915:DRET RS05825
gene id: 485915:DRET_RS05825
uniprot id: C8X1M6
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS11580
gene id: 485915:DRET_RS11580
uniprot id: C8WZL9
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

485915:DRET RS05605
gene id: 485915:DRET_RS05605
uniprot id: C8X283
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

485915:DRET RS01780
gene id: 485915:DRET_RS01780
uniprot id: C8X038
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

485915:DRET RS00095
gene id: 485915:DRET_RS00095
uniprot id: C8WZ45
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS08270
gene id: 485915:DRET_RS08270
uniprot id: C8X3E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

485915:DRET RS10830
gene id: 485915:DRET_RS10830
uniprot id: C8X4V4
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

485915:DRET RS03425
gene id: 485915:DRET_RS03425
uniprot id: C8X0N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

485915:DRET RS02895
gene id: 485915:DRET_RS02895
uniprot id: C8WYV8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

485915:DRET RS07850
gene id: 485915:DRET_RS07850
uniprot id: C8X366
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

485915:DRET RS09180
gene id: 485915:DRET_RS09180
uniprot id: C8X3X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

485915:DRET RS11565
gene id: 485915:DRET_RS11565
uniprot id: C8X594
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

485915:DRET RS00400
gene id: 485915:DRET_RS00400
uniprot id: C8WZA6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

485915:DRET RS02800
gene id: 485915:DRET_RS02800
uniprot id: C8WYU0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

485915:DRET RS03035
gene id: 485915:DRET_RS03035
uniprot id: C8WYY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

485915:DRET RS10490
gene id: 485915:DRET_RS10490
uniprot id: C8X4A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

485915:DRET RS00660
gene id: 485915:DRET_RS00660
uniprot id: C8WZF7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

485915:DRET RS01375
gene id: 485915:DRET_RS01375
uniprot id: C8WZV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

485915:DRET RS11365
gene id: 485915:DRET_RS11365
uniprot id: C8X556
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

485915:DRET RS00715
gene id: 485915:DRET_RS00715
uniprot id: C8WZG8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

485915:DRET RS07420
gene id: 485915:DRET_RS07420
uniprot id: C8X2X4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

485915:DRET RS02605
gene id: 485915:DRET_RS02605
uniprot id: C8X0J5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

485915:DRET RS07710
gene id: 485915:DRET_RS07710
uniprot id: C8X336
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

485915:DRET RS00165
gene id: 485915:DRET_RS00165
uniprot id: C8WZ60
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS05220
gene id: 485915:DRET_RS05220
uniprot id: C8X207
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

485915:DRET RS06930
gene id: 485915:DRET_RS06930
uniprot id: C8X2M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

485915:DRET RS11625
gene id: 485915:DRET_RS11625
uniprot id: C8X5A7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

485915:DRET RS12175
gene id: 485915:DRET_RS12175
uniprot id: C8X5L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

485915:DRET RS07895
gene id: 485915:DRET_RS07895
uniprot id: C8X375
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

485915:DRET RS10875
gene id: 485915:DRET_RS10875
uniprot id: C8X4W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

485915:DRET RS03865
gene id: 485915:DRET_RS03865
uniprot id: C8X0W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

485915:DRET RS00875
gene id: 485915:DRET_RS00875
uniprot id: C8WZK2
names: Similarity
messages: Belongs to the AOR/FOR family.

485915:DRET RS02130
gene id: 485915:DRET_RS02130
uniprot id: C8X0A1
names: Similarity
messages: Belongs to the UPF0045 family.

485915:DRET RS11070
gene id: 485915:DRET_RS11070
uniprot id: C8X4Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

485915:DRET RS07875
gene id: 485915:DRET_RS07875
uniprot id: C8X371
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

485915:DRET RS11415
gene id: 485915:DRET_RS11415
uniprot id: C8X565
names: Similarity
messages: Belongs to the GSP E family.

485915:DRET RS04615
gene id: 485915:DRET_RS04615
uniprot id: C8X1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

485915:DRET RS05145
gene id: 485915:DRET_RS05145
uniprot id: C8X1Z2
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

485915:DRET RS10680
gene id: 485915:DRET_RS10680
uniprot id: C8X4E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

485915:DRET RS09740
gene id: 485915:DRET_RS09740
uniprot id: C8X4L1
names: Similarity
messages: Belongs to the DtxR/MntR family.

485915:DRET RS03595
gene id: 485915:DRET_RS03595
uniprot id: C8X0R4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

485915:DRET RS07870
gene id: 485915:DRET_RS07870
uniprot id: C8X370
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

485915:DRET RS04285
gene id: 485915:DRET_RS04285
uniprot id: C8X141
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

485915:DRET RS10210
gene id: 485915:DRET_RS10210
uniprot id: C8X456
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

485915:DRET RS10120
gene id: 485915:DRET_RS10120
uniprot id: C8X437
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

485915:DRET RS03695
gene id: 485915:DRET_RS03695
uniprot id: C8X0T2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

485915:DRET RS01765
gene id: 485915:DRET_RS01765
uniprot id: C8X034
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS02875
gene id: 485915:DRET_RS02875
uniprot id: C8WYV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

485915:DRET RS11230
gene id: 485915:DRET_RS11230
uniprot id: C8X530
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

485915:DRET RS03730
gene id: 485915:DRET_RS03730
uniprot id: C8X0T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

485915:DRET RS01985
gene id: 485915:DRET_RS01985
uniprot id: C8X075
names: Similarity
messages: Belongs to the glutamate synthase family.

485915:DRET RS05080
gene id: 485915:DRET_RS05080
uniprot id: C8X1K3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

485915:DRET RS08670
gene id: 485915:DRET_RS08670
uniprot id: C8X3M1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

485915:DRET RS00445
gene id: 485915:DRET_RS00445
uniprot id: C8WZB5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS07040
gene id: 485915:DRET_RS07040
uniprot id: C8X2P9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

485915:DRET RS00975
gene id: 485915:DRET_RS00975
uniprot id: C8WZM3
names: Similarity
messages: Belongs to the HdrA family.

485915:DRET RS07120
gene id: 485915:DRET_RS07120
uniprot id: C8X2R4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

485915:DRET RS02460
gene id: 485915:DRET_RS02460
uniprot id: C8X0G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

485915:DRET RS06305
gene id: 485915:DRET_RS06305
uniprot id: C8X1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

485915:DRET RS02025
gene id: 485915:DRET_RS02025
uniprot id: C8X083
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

485915:DRET RS09785
gene id: 485915:DRET_RS09785
uniprot id: C8X4M0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

485915:DRET RS05095
gene id: 485915:DRET_RS05095
uniprot id: C8X1K6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

485915:DRET RS06100
gene id: 485915:DRET_RS06100
uniprot id: C8X1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

485915:DRET RS09290
gene id: 485915:DRET_RS09290
uniprot id: C8X3Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

485915:DRET RS02995
gene id: 485915:DRET_RS02995
uniprot id: C8WYX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

485915:DRET RS04295
gene id: 485915:DRET_RS04295
uniprot id: C8X144
names: Similarity
messages: Belongs to the FBPase class 2 family.

485915:DRET RS05400
gene id: 485915:DRET_RS05400
uniprot id: C8X242
names: Similarity
messages: Belongs to the HypE family.

485915:DRET RS03010
gene id: 485915:DRET_RS03010
uniprot id: C8WYY1
names: Similarity
messages: Belongs to the FlgM family.

485915:DRET RS12900
gene id: 485915:DRET_RS12900
uniprot id: C8X118
names: Similarity
messages: Belongs to the universal stress protein A family.

485915:DRET RS02670
gene id: 485915:DRET_RS02670
uniprot id: C8WYR7
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

485915:DRET RS00425
gene id: 485915:DRET_RS00425
uniprot id: C8WZB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

485915:DRET RS12470
gene id: 485915:DRET_RS12470
uniprot id: C8X5S3
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

485915:DRET RS10345
gene id: 485915:DRET_RS10345
uniprot id: C8X484
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

485915:DRET RS04180
gene id: 485915:DRET_RS04180
uniprot id: C8X122
names: Similarity
messages: Belongs to the CutA family.

485915:DRET RS10845
gene id: 485915:DRET_RS10845
uniprot id: C8X4V7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS04010
gene id: 485915:DRET_RS04010
uniprot id: C8X0Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

485915:DRET RS01535
gene id: 485915:DRET_RS01535
uniprot id: C8WZY5
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS01490
gene id: 485915:DRET_RS01490
uniprot id: C8WZX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS10415
gene id: 485915:DRET_RS10415
uniprot id: C8X493
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

485915:DRET RS10575
gene id: 485915:DRET_RS10575
uniprot id: C8X4C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS01460
gene id: 485915:DRET_RS01460
uniprot id: C8WZX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

485915:DRET RS07090
gene id: 485915:DRET_RS07090
uniprot id: C8X2Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS04190
gene id: 485915:DRET_RS04190
uniprot id: C8X124
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

485915:DRET RS05620
gene id: 485915:DRET_RS05620
uniprot id: C8X286
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

485915:DRET RS12350
gene id: 485915:DRET_RS12350
uniprot id: C8X5P8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS10255
gene id: 485915:DRET_RS10255
uniprot id: C8X466
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

485915:DRET RS10765
gene id: 485915:DRET_RS10765
uniprot id: C8X4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485915:DRET RS02595
gene id: 485915:DRET_RS02595
uniprot id: C8X0J3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

485915:DRET RS00625
gene id: 485915:DRET_RS00625
uniprot id: C8WZF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

485915:DRET RS10090
gene id: 485915:DRET_RS10090
uniprot id: C8X4T2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

485915:DRET RS10920
gene id: 485915:DRET_RS10920
uniprot id: C8X4W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

485915:DRET RS06775
gene id: 485915:DRET_RS06775
uniprot id: C8X2J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

485915:DRET RS07615
gene id: 485915:DRET_RS07615
uniprot id: C8X315
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

485915:DRET RS01035
gene id: 485915:DRET_RS01035
uniprot id: C8WZN5
names: Similarity
messages: Belongs to the MEMO1 family.

485915:DRET RS02505
gene id: 485915:DRET_RS02505
uniprot id: C8X0H6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS00510
gene id: 485915:DRET_RS00510
uniprot id: C8WZC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

485915:DRET RS00710
gene id: 485915:DRET_RS00710
uniprot id: C8WZG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

485915:DRET RS09530
gene id: 485915:DRET_RS09530
uniprot id: C8X4H0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

485915:DRET RS01635
gene id: 485915:DRET_RS01635
uniprot id: C8X006
names: Similarity
messages: Belongs to the CFA/CMAS family.

485915:DRET RS04305
gene id: 485915:DRET_RS04305
uniprot id: C8X146
names: Similarity
messages: Belongs to the LacAB/RpiB family.

485915:DRET RS02680
gene id: 485915:DRET_RS02680
uniprot id: C8WYR9
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS01040
gene id: 485915:DRET_RS01040
uniprot id: C8WZN6
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

485915:DRET RS06580
gene id: 485915:DRET_RS06580
uniprot id: C8X2F5
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

485915:DRET RS03020
gene id: 485915:DRET_RS03020
uniprot id: C8WYY3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

485915:DRET RS08390
gene id: 485915:DRET_RS08390
uniprot id: C8X3H2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

485915:DRET RS08400
gene id: 485915:DRET_RS08400
uniprot id: C8X3H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

485915:DRET RS05820
gene id: 485915:DRET_RS05820
uniprot id: C8X1M5
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS07140
gene id: 485915:DRET_RS07140
uniprot id: C8X2R8
names: Similarity
messages: Belongs to the UPF0758 family.

485915:DRET RS02400
gene id: 485915:DRET_RS02400
uniprot id: C8X0F5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

485915:DRET RS00740
gene id: 485915:DRET_RS00740
uniprot id: C8WZH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

485915:DRET RS06365
gene id: 485915:DRET_RS06365
uniprot id: C8X2B4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

485915:DRET RS05545
gene id: 485915:DRET_RS05545
uniprot id: C8X271
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS10235
gene id: 485915:DRET_RS10235
uniprot id: C8X461
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

485915:DRET RS02750
gene id: 485915:DRET_RS02750
uniprot id: C8WYT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

485915:DRET RS06655
gene id: 485915:DRET_RS06655
uniprot id: C8X2H1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

485915:DRET RS00035
gene id: 485915:DRET_RS00035
uniprot id: C8WZ33
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

485915:DRET RS03570
gene id: 485915:DRET_RS03570
uniprot id: C8X0R0
names: Similarity
messages: Belongs to the LarC family.

485915:DRET RS10775
gene id: 485915:DRET_RS10775
uniprot id: C8X4U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

485915:DRET RS11995
gene id: 485915:DRET_RS11995
uniprot id: C8X5I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

485915:DRET RS01800
gene id: 485915:DRET_RS01800
uniprot id: C8X044
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

485915:DRET RS10200
gene id: 485915:DRET_RS10200
uniprot id: C8X454
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

485915:DRET RS08470
gene id: 485915:DRET_RS08470
uniprot id: C8X3I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

485915:DRET RS11280
gene id: 485915:DRET_RS11280
uniprot id: C8X540
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

485915:DRET RS08385
gene id: 485915:DRET_RS08385
uniprot id: C8X3H1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

485915:DRET RS01095
gene id: 485915:DRET_RS01095
uniprot id: C8WZP7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

485915:DRET RS05350
gene id: 485915:DRET_RS05350
uniprot id: C8X232
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

485915:DRET RS05720
gene id: 485915:DRET_RS05720
uniprot id: C8X2A6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

485915:DRET RS00230
gene id: 485915:DRET_RS00230
uniprot id: C8WZ73
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

485915:DRET RS05410
gene id: 485915:DRET_RS05410
uniprot id: C8X244
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

485915:DRET RS02935
gene id: 485915:DRET_RS02935
uniprot id: C8WYW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

485915:DRET RS07085
gene id: 485915:DRET_RS07085
uniprot id: C8X2Q7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

485915:DRET RS02745
gene id: 485915:DRET_RS02745
uniprot id: C8WYT0
names: Similarity
messages: Belongs to the peptidase C56 family.

485915:DRET RS03800
gene id: 485915:DRET_RS03800
uniprot id: C8X0V3
names: Similarity
messages: Belongs to the universal stress protein A family.

485915:DRET RS10060
gene id: 485915:DRET_RS10060
uniprot id: C8X4S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

485915:DRET RS06845
gene id: 485915:DRET_RS06845
uniprot id: C8X2L1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS05695
gene id: 485915:DRET_RS05695
uniprot id: C8X2A1
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS06120
gene id: 485915:DRET_RS06120
uniprot id: C8X1U0
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS06515
gene id: 485915:DRET_RS06515
uniprot id: C8X2E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

485915:DRET RS11975
gene id: 485915:DRET_RS11975
uniprot id: C8X5H8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

485915:DRET RS02180
gene id: 485915:DRET_RS02180
uniprot id: C8X0B1
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

485915:DRET RS05380
gene id: 485915:DRET_RS05380
uniprot id: C8X238
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

485915:DRET RS01100
gene id: 485915:DRET_RS01100
uniprot id: C8WZP8
names: Similarity
messages: Belongs to the GARS family.

485915:DRET RS10560
gene id: 485915:DRET_RS10560
uniprot id: C8X4C1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS02245
gene id: 485915:DRET_RS02245
uniprot id: C8X0C4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS00175
gene id: 485915:DRET_RS00175
uniprot id: C8WZ62
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

485915:DRET RS10040
gene id: 485915:DRET_RS10040
uniprot id: C8X4S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

485915:DRET RS05190
gene id: 485915:DRET_RS05190
uniprot id: C8X201
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

485915:DRET RS00040
gene id: 485915:DRET_RS00040
uniprot id: C8WZ34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

485915:DRET RS12460
gene id: 485915:DRET_RS12460
uniprot id: C8X5S1
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

485915:DRET RS11485
gene id: 485915:DRET_RS11485
uniprot id: C8X579
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

485915:DRET RS06990
gene id: 485915:DRET_RS06990
uniprot id: C8X2N9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

485915:DRET RS02855
gene id: 485915:DRET_RS02855
uniprot id: C8WYV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

485915:DRET RS01260
gene id: 485915:DRET_RS01260
uniprot id: C8WZT0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

485915:DRET RS09005
gene id: 485915:DRET_RS09005
uniprot id: C8X3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

485915:DRET RS02690
gene id: 485915:DRET_RS02690
uniprot id: C8WYS2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

485915:DRET RS05855
gene id: 485915:DRET_RS05855
uniprot id: C8X1N3
names: Similarity
messages: Belongs to the bacterial secretin family.

485915:DRET RS03720
gene id: 485915:DRET_RS03720
uniprot id: C8X0T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

485915:DRET RS02450
gene id: 485915:DRET_RS02450
uniprot id: C8X0G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

485915:DRET RS01070
gene id: 485915:DRET_RS01070
uniprot id: C8WZP2
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS05310
gene id: 485915:DRET_RS05310
uniprot id: C8X224
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

485915:DRET RS04165
gene id: 485915:DRET_RS04165
uniprot id: C8X119
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS12325
gene id: 485915:DRET_RS12325
uniprot id: C8X5P3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

485915:DRET RS02435
gene id: 485915:DRET_RS02435
uniprot id: C8X0G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

485915:DRET RS00120
gene id: 485915:DRET_RS00120
uniprot id: C8WZ50
names: Similarity
messages: Belongs to the UPF0047 family.

485915:DRET RS11600
gene id: 485915:DRET_RS11600
uniprot id: C8X5A2
names: Similarity
messages: Belongs to the HdrA family.

485915:DRET RS04420
gene id: 485915:DRET_RS04420
uniprot id: C8X171
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

485915:DRET RS10330
gene id: 485915:DRET_RS10330
uniprot id: C8X481
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

485915:DRET RS01500
gene id: 485915:DRET_RS01500
uniprot id: C8WZX8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

485915:DRET RS04395
gene id: 485915:DRET_RS04395
uniprot id: C8X165
names: Similarity
messages: Belongs to the universal stress protein A family.

485915:DRET RS08245
gene id: 485915:DRET_RS08245
uniprot id: C8X3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

485915:DRET RS02550
gene id: 485915:DRET_RS02550
uniprot id: C8X0I4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

485915:DRET RS02315
gene id: 485915:DRET_RS02315
uniprot id: C8X0D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

485915:DRET RS08615
gene id: 485915:DRET_RS08615
uniprot id: C8X3L0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

485915:DRET RS09730
gene id: 485915:DRET_RS09730
uniprot id: C8X4K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

485915:DRET RS01315
gene id: 485915:DRET_RS01315
uniprot id: C8WZU1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

485915:DRET RS01025
gene id: 485915:DRET_RS01025
uniprot id: C8WZN3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

485915:DRET RS10085
gene id: 485915:DRET_RS10085
uniprot id: C8X4T1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

485915:DRET RS07725
gene id: 485915:DRET_RS07725
uniprot id: C8X339
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

485915:DRET RS09770
gene id: 485915:DRET_RS09770
uniprot id: C8X4L7
names: Similarity
messages: Belongs to the Ahb/Nir family.

485915:DRET RS10195
gene id: 485915:DRET_RS10195
uniprot id: C8X452
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

485915:DRET RS02110
gene id: 485915:DRET_RS02110
uniprot id: C8X098
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS02635
gene id: 485915:DRET_RS02635
uniprot id: C8WYR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

485915:DRET RS08535
gene id: 485915:DRET_RS08535
uniprot id: C8X3K0
names: Similarity
messages: Belongs to the peptidase C56 family.

485915:DRET RS12480
gene id: 485915:DRET_RS12480
uniprot id: C8X5S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485915:DRET RS11890
gene id: 485915:DRET_RS11890
uniprot id: C8X5G1
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS12230
gene id: 485915:DRET_RS12230
uniprot id: C8X5M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

485915:DRET RS03055
gene id: 485915:DRET_RS03055
uniprot id: C8WYZ0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

485915:DRET RS09115
gene id: 485915:DRET_RS09115
uniprot id: C8X3V8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

485915:DRET RS00200
gene id: 485915:DRET_RS00200
uniprot id: C8WZ68
names: Similarity
messages: Belongs to the disproportionating enzyme family.

485915:DRET RS04205
gene id: 485915:DRET_RS04205
uniprot id: C8X127
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

485915:DRET RS07320
gene id: 485915:DRET_RS07320
uniprot id: C8X2V4
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS09520
gene id: 485915:DRET_RS09520
uniprot id: C8X4G8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

485915:DRET RS01380
gene id: 485915:DRET_RS01380
uniprot id: C8WZV3
names: Similarity
messages: Belongs to the peptidase M29 family.

485915:DRET RS09800
gene id: 485915:DRET_RS09800
uniprot id: C8X4M4
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS08765
gene id: 485915:DRET_RS08765
uniprot id: C8X3N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

485915:DRET RS03470
gene id: 485915:DRET_RS03470
uniprot id: C8X0N9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

485915:DRET RS02540
gene id: 485915:DRET_RS02540
uniprot id: C8X0I2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

485915:DRET RS07985
gene id: 485915:DRET_RS07985
uniprot id: C8X393
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

485915:DRET RS10625
gene id: 485915:DRET_RS10625
uniprot id: C8X4D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

485915:DRET RS04960
gene id: 485915:DRET_RS04960
uniprot id: C8X1I0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

485915:DRET RS07490
gene id: 485915:DRET_RS07490
uniprot id: C8X2Y7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

485915:DRET RS05445
gene id: 485915:DRET_RS05445
uniprot id: C8X251
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

485915:DRET RS00225
gene id: 485915:DRET_RS00225
uniprot id: C8WZ72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

485915:DRET RS08520
gene id: 485915:DRET_RS08520
uniprot id: C8X3J7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

485915:DRET RS03650
gene id: 485915:DRET_RS03650
uniprot id: C8X0S5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

485915:DRET RS02520
gene id: 485915:DRET_RS02520
uniprot id: C8X0H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

485915:DRET RS10750
gene id: 485915:DRET_RS10750
uniprot id: C8X4T8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

485915:DRET RS06520
gene id: 485915:DRET_RS06520
uniprot id: C8X2E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

485915:DRET RS05985
gene id: 485915:DRET_RS05985
uniprot id: C8X1R1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

485915:DRET RS10870
gene id: 485915:DRET_RS10870
uniprot id: C8X4W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

485915:DRET RS06850
gene id: 485915:DRET_RS06850
uniprot id: C8X2L2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

485915:DRET RS05180
gene id: 485915:DRET_RS05180
uniprot id: C8X1Z9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

485915:DRET RS09700
gene id: 485915:DRET_RS09700
uniprot id: C8X4K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

485915:DRET RS00540
gene id: 485915:DRET_RS00540
uniprot id: C8WZD4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

485915:DRET RS10055
gene id: 485915:DRET_RS10055
uniprot id: C8X4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

485915:DRET RS09525
gene id: 485915:DRET_RS09525
uniprot id: C8X4G9
names: Similarity
messages: Belongs to the thioredoxin family.

485915:DRET RS01255
gene id: 485915:DRET_RS01255
uniprot id: C8WZS9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

485915:DRET RS03325
gene id: 485915:DRET_RS03325
uniprot id: C8X0L0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

485915:DRET RS05085
gene id: 485915:DRET_RS05085
uniprot id: C8X1K4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

485915:DRET RS00845
gene id: 485915:DRET_RS00845
uniprot id: C8WZJ6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

485915:DRET RS06725
gene id: 485915:DRET_RS06725
uniprot id: C8X2I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485915:DRET RS01975
gene id: 485915:DRET_RS01975
uniprot id: C8X074
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS03455
gene id: 485915:DRET_RS03455
uniprot id: C8X0N6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

485915:DRET RS05945
gene id: 485915:DRET_RS05945
uniprot id: C8X1Q3
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS06735
gene id: 485915:DRET_RS06735
uniprot id: C8X2I7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

485915:DRET RS09680
gene id: 485915:DRET_RS09680
uniprot id: C8X4J9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

485915:DRET RS05980
gene id: 485915:DRET_RS05980
uniprot id: C8X1R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

485915:DRET RS05435
gene id: 485915:DRET_RS05435
uniprot id: C8X249
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

485915:DRET RS07325
gene id: 485915:DRET_RS07325
uniprot id: C8X2V5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

485915:DRET RS10545
gene id: 485915:DRET_RS10545
uniprot id: C8X4B8
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

485915:DRET RS04155
gene id: 485915:DRET_RS04155
uniprot id: C8X117
names: Similarity
messages: Belongs to the peptidase S16 family.

485915:DRET RS01680
gene id: 485915:DRET_RS01680
uniprot id: C8X017
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

485915:DRET RS00730
gene id: 485915:DRET_RS00730
uniprot id: C8WZH1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

485915:DRET RS12355
gene id: 485915:DRET_RS12355
uniprot id: C8X5P9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

485915:DRET RS07305
gene id: 485915:DRET_RS07305
uniprot id: C8X2V1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

485915:DRET RS04940
gene id: 485915:DRET_RS04940
uniprot id: C8X1H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

485915:DRET RS09830
gene id: 485915:DRET_RS09830
uniprot id: C8X4N0
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS00495
gene id: 485915:DRET_RS00495
uniprot id: C8WZC5
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

485915:DRET RS07020
gene id: 485915:DRET_RS07020
uniprot id: C8X2P5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

485915:DRET RS07300
gene id: 485915:DRET_RS07300
uniprot id: C8X2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

485915:DRET RS08960
gene id: 485915:DRET_RS08960
uniprot id: C8X3S7
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

485915:DRET RS11305
gene id: 485915:DRET_RS11305
uniprot id: C8X545
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

485915:DRET RS00025
gene id: 485915:DRET_RS00025
uniprot id: C8WZ31
names: Similarity
messages: Belongs to the ParB family.

485915:DRET RS12050
gene id: 485915:DRET_RS12050
uniprot id: C8X5J3
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

485915:DRET RS07080
gene id: 485915:DRET_RS07080
uniprot id: C8X2Q6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

485915:DRET RS01390
gene id: 485915:DRET_RS01390
uniprot id: C8WZV5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

485915:DRET RS10245
gene id: 485915:DRET_RS10245
uniprot id: C8X464
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

485915:DRET RS10215
gene id: 485915:DRET_RS10215
uniprot id: C8X457
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

485915:DRET RS05265
gene id: 485915:DRET_RS05265
uniprot id: C8X216
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

485915:DRET RS11265
gene id: 485915:DRET_RS11265
uniprot id: C8X537
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

485915:DRET RS10790
gene id: 485915:DRET_RS10790
uniprot id: C8X4U6
names: Similarity
messages: Belongs to the peptidase S41A family.

485915:DRET RS12495
gene id: 485915:DRET_RS12495
uniprot id: C8X5S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

485915:DRET RS05430
gene id: 485915:DRET_RS05430
uniprot id: C8X248
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

485915:DRET RS06415
gene id: 485915:DRET_RS06415
uniprot id: C8X2C4
names: Similarity
messages: Belongs to the acylphosphatase family.

485915:DRET RS11340
gene id: 485915:DRET_RS11340
uniprot id: C8X551
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS06740
gene id: 485915:DRET_RS06740
uniprot id: C8X2I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

485915:DRET RS12075
gene id: 485915:DRET_RS12075
uniprot id: C8X5J8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

485915:DRET RS04455
gene id: 485915:DRET_RS04455
uniprot id: C8X179
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

485915:DRET RS08290
gene id: 485915:DRET_RS08290
uniprot id: C8X3F2
names: Similarity
messages: Belongs to the YggT family.

485915:DRET RS10705
gene id: 485915:DRET_RS10705
uniprot id: C8X4E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

485915:DRET RS05760
gene id: 485915:DRET_RS05760
uniprot id: C8X1L4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

485915:DRET RS03660
gene id: 485915:DRET_RS03660
uniprot id: C8X0S6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

485915:DRET RS11235
gene id: 485915:DRET_RS11235
uniprot id: C8X531
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS08980
gene id: 485915:DRET_RS08980
uniprot id: C8X3T1
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS06915
gene id: 485915:DRET_RS06915
uniprot id: C8X2M4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

485915:DRET RS10295
gene id: 485915:DRET_RS10295
uniprot id: C8X474
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

485915:DRET RS01325
gene id: 485915:DRET_RS01325
uniprot id: C8WZU3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

485915:DRET RS10520
gene id: 485915:DRET_RS10520
uniprot id: C8X4B3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

485915:DRET RS05830
gene id: 485915:DRET_RS05830
uniprot id: C8X1M7
names: Similarity
messages: Belongs to the GSP E family.

485915:DRET RS09490
gene id: 485915:DRET_RS09490
uniprot id: C8X4G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

485915:DRET RS05195
gene id: 485915:DRET_RS05195
uniprot id: C8X202
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

485915:DRET RS10350
gene id: 485915:DRET_RS10350
uniprot id: C8X485
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

485915:DRET RS00100
gene id: 485915:DRET_RS00100
uniprot id: C8WZ46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

485915:DRET RS07910
gene id: 485915:DRET_RS07910
uniprot id: C8X378
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

485915:DRET RS01190
gene id: 485915:DRET_RS01190
uniprot id: C8WZR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

485915:DRET RS12385
gene id: 485915:DRET_RS12385
uniprot id: C8X5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

485915:DRET RS02415
gene id: 485915:DRET_RS02415
uniprot id: C8X0F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

485915:DRET RS07220
gene id: 485915:DRET_RS07220
uniprot id: C8X2T4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

485915:DRET RS09790
gene id: 485915:DRET_RS09790
uniprot id: C8X4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

485915:DRET RS06265
gene id: 485915:DRET_RS06265
uniprot id: C8X1X0
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

485915:DRET RS02555
gene id: 485915:DRET_RS02555
uniprot id: C8X0I5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

485915:DRET RS06050
gene id: 485915:DRET_RS06050
uniprot id: C8X1S4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

485915:DRET RS12115
gene id: 485915:DRET_RS12115
uniprot id: C8X5K6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS04350
gene id: 485915:DRET_RS04350
uniprot id: C8X156
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

485915:DRET RS07355
gene id: 485915:DRET_RS07355
uniprot id: C8X2W1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

485915:DRET RS01545
gene id: 485915:DRET_RS01545
uniprot id: C8WZY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

485915:DRET RS05075
gene id: 485915:DRET_RS05075
uniprot id: C8X1K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

485915:DRET RS07790
gene id: 485915:DRET_RS07790
uniprot id: C8X353
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

485915:DRET RS03980
gene id: 485915:DRET_RS03980
uniprot id: C8X0Y5
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS03270
gene id: 485915:DRET_RS03270
uniprot id: C8X0J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

485915:DRET RS04975
gene id: 485915:DRET_RS04975
uniprot id: C8X1I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

485915:DRET RS11715
gene id: 485915:DRET_RS11715
uniprot id: C8X5C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

485915:DRET RS00060
gene id: 485915:DRET_RS00060
uniprot id: C8WZ38
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

485915:DRET RS10095
gene id: 485915:DRET_RS10095
uniprot id: C8X432
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

485915:DRET RS09630
gene id: 485915:DRET_RS09630
uniprot id: C8X4J0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

485915:DRET RS08820
gene id: 485915:DRET_RS08820
uniprot id: C8X3P6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

485915:DRET RS00505
gene id: 485915:DRET_RS00505
uniprot id: C8WZC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

485915:DRET RS05065
gene id: 485915:DRET_RS05065
uniprot id: C8X1K0
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS03670
gene id: 485915:DRET_RS03670
uniprot id: C8X0S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

485915:DRET RS10815
gene id: 485915:DRET_RS10815
uniprot id: C8X4V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

485915:DRET RS08250
gene id: 485915:DRET_RS08250
uniprot id: C8X3E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

485915:DRET RS09475
gene id: 485915:DRET_RS09475
uniprot id: C8X4F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

485915:DRET RS04995
gene id: 485915:DRET_RS04995
uniprot id: C8X1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

485915:DRET RS06335
gene id: 485915:DRET_RS06335
uniprot id: C8X1Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

485915:DRET RS11820
gene id: 485915:DRET_RS11820
uniprot id: C8X5E6
names: Subunit
messages: Heterodimer of a large and a small subunit.

485915:DRET RS11145
gene id: 485915:DRET_RS11145
uniprot id: C8X514
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

485915:DRET RS05660
gene id: 485915:DRET_RS05660
uniprot id: C8X294
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

485915:DRET RS07280
gene id: 485915:DRET_RS07280
uniprot id: C8X2U6
names: Similarity
messages: Belongs to the TlyA family.

485915:DRET RS04280
gene id: 485915:DRET_RS04280
uniprot id: C8X140
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

485915:DRET RS12015
gene id: 485915:DRET_RS12015
uniprot id: C8X5I6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

485915:DRET RS12320
gene id: 485915:DRET_RS12320
uniprot id: C8X5P2
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS01160
gene id: 485915:DRET_RS01160
uniprot id: C8WZR0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

485915:DRET RS02065
gene id: 485915:DRET_RS02065
uniprot id: C8X090
names: Similarity
messages: Belongs to the HdrA family.

485915:DRET RS11685
gene id: 485915:DRET_RS11685
uniprot id: C8X5B7
names: Similarity
messages: Belongs to the leucine-binding protein family.

485915:DRET RS01250
gene id: 485915:DRET_RS01250
uniprot id: C8WZS8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

485915:DRET RS03400
gene id: 485915:DRET_RS03400
uniprot id: C8X0M4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

485915:DRET RS06475
gene id: 485915:DRET_RS06475
uniprot id: C8X2D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485915:DRET RS10135
gene id: 485915:DRET_RS10135
uniprot id: C8X440
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485915:DRET RS00700
gene id: 485915:DRET_RS00700
uniprot id: C8WZG5
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

485915:DRET RS11445
gene id: 485915:DRET_RS11445
uniprot id: C8X571
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

485915:DRET RS02425
gene id: 485915:DRET_RS02425
uniprot id: C8X0G0
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

485915:DRET RS06910
gene id: 485915:DRET_RS06910
uniprot id: C8X2M3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

485915:DRET RS12390
gene id: 485915:DRET_RS12390
uniprot id: C8X5Q7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

485915:DRET RS06045
gene id: 485915:DRET_RS06045
uniprot id: C8X1S3
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

485915:DRET RS05370
gene id: 485915:DRET_RS05370
uniprot id: C8X236
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

485915:DRET RS00105
gene id: 485915:DRET_RS00105
uniprot id: C8WZ47
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

485915:DRET RS05335
gene id: 485915:DRET_RS05335
uniprot id: C8X229
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

485915:DRET RS12400
gene id: 485915:DRET_RS12400
uniprot id: C8X5Q9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

485915:DRET RS05215
gene id: 485915:DRET_RS05215
uniprot id: C8X206
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

485915:DRET RS04985
gene id: 485915:DRET_RS04985
uniprot id: C8X1I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

485915:DRET RS09390
gene id: 485915:DRET_RS09390
uniprot id: C8X414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

485915:DRET RS02830
gene id: 485915:DRET_RS02830
uniprot id: C8WYU5
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS09565
gene id: 485915:DRET_RS09565
uniprot id: C8X4H7
names: Similarity
messages: Belongs to the GSP E family.

485915:DRET RS03155
gene id: 485915:DRET_RS03155
uniprot id: C8WZ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

485915:DRET RS08650
gene id: 485915:DRET_RS08650
uniprot id: C8X3L6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

485915:DRET RS12030
gene id: 485915:DRET_RS12030
uniprot id: C8X5I9
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

485915:DRET RS07065
gene id: 485915:DRET_RS07065
uniprot id: C8X2Q4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

485915:DRET RS10435
gene id: 485915:DRET_RS10435
uniprot id: C8X497
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

485915:DRET RS09715
gene id: 485915:DRET_RS09715
uniprot id: C8X4K6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

485915:DRET RS10035
gene id: 485915:DRET_RS10035
uniprot id: C8X4S1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

485915:DRET RS07960
gene id: 485915:DRET_RS07960
uniprot id: C8X388
names: Similarity
messages: Belongs to the sigma-54 factor family.

485915:DRET RS01085
gene id: 485915:DRET_RS01085
uniprot id: C8WZP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

485915:DRET RS00215
gene id: 485915:DRET_RS00215
uniprot id: C8WZ70
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS02545
gene id: 485915:DRET_RS02545
uniprot id: C8X0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

485915:DRET RS00045
gene id: 485915:DRET_RS00045
uniprot id: C8WZ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

485915:DRET RS10335
gene id: 485915:DRET_RS10335
uniprot id: C8X482
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

485915:DRET RS07705
gene id: 485915:DRET_RS07705
uniprot id: C8X335
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

485915:DRET RS08885
gene id: 485915:DRET_RS08885
uniprot id: C8X3R1
names: Similarity
messages: Belongs to the UPF0173 family.

485915:DRET RS08395
gene id: 485915:DRET_RS08395
uniprot id: C8X3H3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

485915:DRET RS05320
gene id: 485915:DRET_RS05320
uniprot id: C8X226
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

485915:DRET RS03190
gene id: 485915:DRET_RS03190
uniprot id: C8WZ15
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

485915:DRET RS09595
gene id: 485915:DRET_RS09595
uniprot id: C8X4I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

485915:DRET RS03985
gene id: 485915:DRET_RS03985
uniprot id: C8X0Y6
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS02890
gene id: 485915:DRET_RS02890
uniprot id: C8WYV7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

485915:DRET RS00110
gene id: 485915:DRET_RS00110
uniprot id: C8WZ48
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

485915:DRET RS02240
gene id: 485915:DRET_RS02240
uniprot id: C8X0C3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

485915:DRET RS08480
gene id: 485915:DRET_RS08480
uniprot id: C8X3I9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS10075
gene id: 485915:DRET_RS10075
uniprot id: C8X4S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

485915:DRET RS07740
gene id: 485915:DRET_RS07740
uniprot id: C8X342
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS07290
gene id: 485915:DRET_RS07290
uniprot id: C8X2U8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

485915:DRET RS01520
gene id: 485915:DRET_RS01520
uniprot id: C8WZY2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

485915:DRET RS13040
gene id: 485915:DRET_RS13040
uniprot id: C8X3K3
names: Similarity
messages: Belongs to the ParB family.

485915:DRET RS05590
gene id: 485915:DRET_RS05590
uniprot id: C8X280
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS06500
gene id: 485915:DRET_RS06500
uniprot id: C8X2D9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

485915:DRET RS09340
gene id: 485915:DRET_RS09340
uniprot id: C8X403
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

485915:DRET RS00420
gene id: 485915:DRET_RS00420
uniprot id: C8WZB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

485915:DRET RS11075
gene id: 485915:DRET_RS11075
uniprot id: C8X500
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

485915:DRET RS07840
gene id: 485915:DRET_RS07840
uniprot id: C8X364
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

485915:DRET RS09155
gene id: 485915:DRET_RS09155
uniprot id: C8X3W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

485915:DRET RS06660
gene id: 485915:DRET_RS06660
uniprot id: C8X2H2
names: Subcellular Location Annotation
messages: Nucleus

485915:DRET RS12140
gene id: 485915:DRET_RS12140
uniprot id: C8X5L1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

485915:DRET RS09605
gene id: 485915:DRET_RS09605
uniprot id: C8X4I5
names: Similarity
messages: Belongs to the peptidase A31 family.

485915:DRET RS12840
gene id: 485915:DRET_RS12840
uniprot id: C8WYX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

485915:DRET RS01290
gene id: 485915:DRET_RS01290
uniprot id: C8WZT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

485915:DRET RS03920
gene id: 485915:DRET_RS03920
uniprot id: C8X0X4
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS10355
gene id: 485915:DRET_RS10355
uniprot id: C8X486
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

485915:DRET RS11175
gene id: 485915:DRET_RS11175
uniprot id: C8X520
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS11290
gene id: 485915:DRET_RS11290
uniprot id: C8X542
names: Cofactor
messages: Binds 1 zinc ion per subunit.

485915:DRET RS05090
gene id: 485915:DRET_RS05090
uniprot id: C8X1K5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

485915:DRET RS10425
gene id: 485915:DRET_RS10425
uniprot id: C8X495
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

485915:DRET RS03770
gene id: 485915:DRET_RS03770
uniprot id: C8X0U7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

485915:DRET RS01605
gene id: 485915:DRET_RS01605
uniprot id: C8X000
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS12440
gene id: 485915:DRET_RS12440
uniprot id: C8X5R7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS05570
gene id: 485915:DRET_RS05570
uniprot id: C8X276
names: Similarity
messages: Belongs to the SAICAR synthetase family.

485915:DRET RS10630
gene id: 485915:DRET_RS10630
uniprot id: C8X4D5
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS12080
gene id: 485915:DRET_RS12080
uniprot id: C8X5J9
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

485915:DRET RS03940
gene id: 485915:DRET_RS03940
uniprot id: C8X0X7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

485915:DRET RS03160
gene id: 485915:DRET_RS03160
uniprot id: C8WZ09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

485915:DRET RS10475
gene id: 485915:DRET_RS10475
uniprot id: C8X4A4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS02385
gene id: 485915:DRET_RS02385
uniprot id: C8X0F2
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

485915:DRET RS04490
gene id: 485915:DRET_RS04490
uniprot id: C8X185
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

485915:DRET RS08635
gene id: 485915:DRET_RS08635
uniprot id: C8X3L4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

485915:DRET RS06935
gene id: 485915:DRET_RS06935
uniprot id: C8X2M8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

485915:DRET RS10275
gene id: 485915:DRET_RS10275
uniprot id: C8X470
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

485915:DRET RS01730
gene id: 485915:DRET_RS01730
uniprot id: C8X026
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

485915:DRET RS11930
gene id: 485915:DRET_RS11930
uniprot id: C8X5G9
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

485915:DRET RS05205
gene id: 485915:DRET_RS05205
uniprot id: C8X204
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

485915:DRET RS07500
gene id: 485915:DRET_RS07500
uniprot id: C8X1K6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

485915:DRET RS10260
gene id: 485915:DRET_RS10260
uniprot id: C8X467
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

485915:DRET RS07845
gene id: 485915:DRET_RS07845
uniprot id: C8X365
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

485915:DRET RS10695
gene id: 485915:DRET_RS10695
uniprot id: C8X4E7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS11955
gene id: 485915:DRET_RS11955
uniprot id: C8X5H4
names: Similarity
messages: Belongs to the glutamine synthetase family.

485915:DRET RS05360
gene id: 485915:DRET_RS05360
uniprot id: C8X234
names: Similarity
messages: Belongs to the class-I fumarase family.

485915:DRET RS03385
gene id: 485915:DRET_RS03385
uniprot id: C8X0M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

485915:DRET RS08260
gene id: 485915:DRET_RS08260
uniprot id: C8X3E6
names: Similarity
messages: Belongs to the GSP E family.

485915:DRET RS03600
gene id: 485915:DRET_RS03600
uniprot id: C8X0R5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

485915:DRET RS08900
gene id: 485915:DRET_RS08900
uniprot id: C8X3R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

485915:DRET RS10430
gene id: 485915:DRET_RS10430
uniprot id: C8X496
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

485915:DRET RS08590
gene id: 485915:DRET_RS08590
uniprot id: C8X3K6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS05010
gene id: 485915:DRET_RS05010
uniprot id: C8X1J0
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS02560
gene id: 485915:DRET_RS02560
uniprot id: C8X0I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

485915:DRET RS07820
gene id: 485915:DRET_RS07820
uniprot id: C8X360
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

485915:DRET RS03430
gene id: 485915:DRET_RS03430
uniprot id: C8X0N1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

485915:DRET RS12065
gene id: 485915:DRET_RS12065
uniprot id: C8X5J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

485915:DRET RS06430
gene id: 485915:DRET_RS06430
uniprot id: C8X2C7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

485915:DRET RS01755
gene id: 485915:DRET_RS01755
uniprot id: C8X032
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

485915:DRET RS07855
gene id: 485915:DRET_RS07855
uniprot id: C8X367
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

485915:DRET RS12125
gene id: 485915:DRET_RS12125
uniprot id: C8X5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

485915:DRET RS01045
gene id: 485915:DRET_RS01045
uniprot id: C8WZN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

485915:DRET RS06685
gene id: 485915:DRET_RS06685
uniprot id: C8X2H7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

485915:DRET RS04050
gene id: 485915:DRET_RS04050
uniprot id: C8X0Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

485915:DRET RS05540
gene id: 485915:DRET_RS05540
uniprot id: C8X270
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

485915:DRET RS02335
gene id: 485915:DRET_RS02335
uniprot id: C8X0E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

485915:DRET RS10540
gene id: 485915:DRET_RS10540
uniprot id: C8X4B7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485915:DRET RS01655
gene id: 485915:DRET_RS01655
uniprot id: C8X010
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

485915:DRET RS10070
gene id: 485915:DRET_RS10070
uniprot id: C8X4S8
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS06920
gene id: 485915:DRET_RS06920
uniprot id: C8X2M5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

485915:DRET RS09485
gene id: 485915:DRET_RS09485
uniprot id: C8X4G1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

485915:DRET RS00590
gene id: 485915:DRET_RS00590
uniprot id: C8WZE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

485915:DRET RS11275
gene id: 485915:DRET_RS11275
uniprot id: C8X539
names: Similarity
messages: Belongs to the pyruvate kinase family.

485915:DRET RS00725
gene id: 485915:DRET_RS00725
uniprot id: C8WZH0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS06570
gene id: 485915:DRET_RS06570
uniprot id: C8X2F3
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

485915:DRET RS08760
gene id: 485915:DRET_RS08760
uniprot id: C8X3N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

485915:DRET RS02220
gene id: 485915:DRET_RS02220
uniprot id: C8X0C0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

485915:DRET RS11045
gene id: 485915:DRET_RS11045
uniprot id: C8X4Z4
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

485915:DRET RS08800
gene id: 485915:DRET_RS08800
uniprot id: C8X3P2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

485915:DRET RS09370
gene id: 485915:DRET_RS09370
uniprot id: C8X410
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS10100
gene id: 485915:DRET_RS10100
uniprot id: C8X433
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

485915:DRET RS01270
gene id: 485915:DRET_RS01270
uniprot id: C8WZT2
names: Similarity
messages: Belongs to the TrpF family.

485915:DRET RS03025
gene id: 485915:DRET_RS03025
uniprot id: C8WYY4
names: Similarity
messages: Belongs to the bacterial flagellin family.

485915:DRET RS05495
gene id: 485915:DRET_RS05495
uniprot id: C8X261
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

485915:DRET RS09805
gene id: 485915:DRET_RS09805
uniprot id: C8X4M5
names: Similarity
messages: Belongs to the HdrA family.

485915:DRET RS00470
gene id: 485915:DRET_RS00470
uniprot id: C8WZC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

485915:DRET RS05405
gene id: 485915:DRET_RS05405
uniprot id: C8X243
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

485915:DRET RS09685
gene id: 485915:DRET_RS09685
uniprot id: C8X4K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

485915:DRET RS05475
gene id: 485915:DRET_RS05475
uniprot id: C8X257
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

485915:DRET RS07810
gene id: 485915:DRET_RS07810
uniprot id: C8X357
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

485915:DRET RS06495
gene id: 485915:DRET_RS06495
uniprot id: C8X2D8
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS07215
gene id: 485915:DRET_RS07215
uniprot id: C8X2T3
names: Similarity
messages: Belongs to the SUI1 family.

485915:DRET RS07095
gene id: 485915:DRET_RS07095
uniprot id: C8X2Q9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

485915:DRET RS02940
gene id: 485915:DRET_RS02940
uniprot id: C8WYW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

485915:DRET RS09955
gene id: 485915:DRET_RS09955
uniprot id: C8X4Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

485915:DRET RS02500
gene id: 485915:DRET_RS02500
uniprot id: C8X0H5
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

485915:DRET RS08825
gene id: 485915:DRET_RS08825
uniprot id: C8X3P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

485915:DRET RS10440
gene id: 485915:DRET_RS10440
uniprot id: C8X498
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS08525
gene id: 485915:DRET_RS08525
uniprot id: C8X3J8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

485915:DRET RS02915
gene id: 485915:DRET_RS02915
uniprot id: C8WYW2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

485915:DRET RS04250
gene id: 485915:DRET_RS04250
uniprot id: C8X135
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

485915:DRET RS03835
gene id: 485915:DRET_RS03835
uniprot id: C8X0V8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS05245
gene id: 485915:DRET_RS05245
uniprot id: C8X212
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS03990
gene id: 485915:DRET_RS03990
uniprot id: C8X0Y7
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS04110
gene id: 485915:DRET_RS04110
uniprot id: C8X108
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

485915:DRET RS07410
gene id: 485915:DRET_RS07410
uniprot id: C8X2X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

485915:DRET RS00610
gene id: 485915:DRET_RS00610
uniprot id: C8WZE8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS05345
gene id: 485915:DRET_RS05345
uniprot id: C8X231
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

485915:DRET RS05490
gene id: 485915:DRET_RS05490
uniprot id: C8X260
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

485915:DRET RS08605
gene id: 485915:DRET_RS08605
uniprot id: C8X3K9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

485915:DRET RS06510
gene id: 485915:DRET_RS06510
uniprot id: C8X2E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

485915:DRET RS02185
gene id: 485915:DRET_RS02185
uniprot id: C8X0B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

485915:DRET RS10840
gene id: 485915:DRET_RS10840
uniprot id: C8X4V6
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

485915:DRET RS02390
gene id: 485915:DRET_RS02390
uniprot id: C8X0F3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

485915:DRET RS05530
gene id: 485915:DRET_RS05530
uniprot id: C8X268
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

485915:DRET RS04495
gene id: 485915:DRET_RS04495
uniprot id: C8X186
names: Similarity
messages: Belongs to the Nth/MutY family.

485915:DRET RS03840
gene id: 485915:DRET_RS03840
uniprot id: C8X0V9
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS01550
gene id: 485915:DRET_RS01550
uniprot id: C8WZY8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

485915:DRET RS12070
gene id: 485915:DRET_RS12070
uniprot id: C8X5J7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

485915:DRET RS03845
gene id: 485915:DRET_RS03845
uniprot id: C8X0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

485915:DRET RS00830
gene id: 485915:DRET_RS00830
uniprot id: C8WZJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

485915:DRET RS05485
gene id: 485915:DRET_RS05485
uniprot id: C8X259
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

485915:DRET RS09840
gene id: 485915:DRET_RS09840
uniprot id: C8X4N2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

485915:DRET RS11380
gene id: 485915:DRET_RS11380
uniprot id: C8X559
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

485915:DRET RS11775
gene id: 485915:DRET_RS11775
uniprot id: C8X5D7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

485915:DRET RS09500
gene id: 485915:DRET_RS09500
uniprot id: C8X4G4
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

485915:DRET RS05120
gene id: 485915:DRET_RS05120
uniprot id: C8X1Y6
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS12465
gene id: 485915:DRET_RS12465
uniprot id: C8X5S2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS02440
gene id: 485915:DRET_RS02440
uniprot id: C8X0G3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

485915:DRET RS03900
gene id: 485915:DRET_RS03900
uniprot id: C8X0X0
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS03175
gene id: 485915:DRET_RS03175
uniprot id: C8WZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

485915:DRET RS02480
gene id: 485915:DRET_RS02480
uniprot id: C8X0H1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS04040
gene id: 485915:DRET_RS04040
uniprot id: C8X0Z5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

485915:DRET RS08285
gene id: 485915:DRET_RS08285
uniprot id: C8X3F1
names: Similarity
messages: Belongs to the UPF0235 family.

485915:DRET RS06465
gene id: 485915:DRET_RS06465
uniprot id: C8X2D2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

485915:DRET RS00140
gene id: 485915:DRET_RS00140
uniprot id: C8WZ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

485915:DRET RS10240
gene id: 485915:DRET_RS10240
uniprot id: C8X463
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

485915:DRET RS02945
gene id: 485915:DRET_RS02945
uniprot id: C8WYW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

485915:DRET RS04485
gene id: 485915:DRET_RS04485
uniprot id: C8X184
names: Similarity
messages: Belongs to the DprA/Smf family.

485915:DRET RS00685
gene id: 485915:DRET_RS00685
uniprot id: C8WZG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

485915:DRET RS03725
gene id: 485915:DRET_RS03725
uniprot id: C8X0T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

485915:DRET RS08355
gene id: 485915:DRET_RS08355
uniprot id: C8X3G5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS07125
gene id: 485915:DRET_RS07125
uniprot id: C8X2R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

485915:DRET RS02705
gene id: 485915:DRET_RS02705
uniprot id: C8WYS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

485915:DRET RS00770
gene id: 485915:DRET_RS00770
uniprot id: C8WZI1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

485915:DRET RS03825
gene id: 485915:DRET_RS03825
uniprot id: C8X0V7
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

485915:DRET RS12135
gene id: 485915:DRET_RS12135
uniprot id: C8X5L0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

485915:DRET RS08475
gene id: 485915:DRET_RS08475
uniprot id: C8X3I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

485915:DRET RS07890
gene id: 485915:DRET_RS07890
uniprot id: C8X374
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

485915:DRET RS10280
gene id: 485915:DRET_RS10280
uniprot id: C8X471
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

485915:DRET RS02715
gene id: 485915:DRET_RS02715
uniprot id: C8WYS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

485915:DRET RS03555
gene id: 485915:DRET_RS03555
uniprot id: C8X0Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

485915:DRET RS09970
gene id: 485915:DRET_RS09970
uniprot id: C8X4Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

485915:DRET RS12120
gene id: 485915:DRET_RS12120
uniprot id: C8X5K7
names: Similarity
messages: Belongs to the Ahb/Nir family.

485915:DRET RS10110
gene id: 485915:DRET_RS10110
uniprot id: C8X435
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

485915:DRET RS05690
gene id: 485915:DRET_RS05690
uniprot id: C8X2A0
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS12290
gene id: 485915:DRET_RS12290
uniprot id: C8X5N6
names: Similarity
messages: Belongs to the ribF family.

485915:DRET RS11100
gene id: 485915:DRET_RS11100
uniprot id: C8X505
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

485915:DRET RS10515
gene id: 485915:DRET_RS10515
uniprot id: C8X4B2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

485915:DRET RS10850
gene id: 485915:DRET_RS10850
uniprot id: C8X4V8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

485915:DRET RS03745
gene id: 485915:DRET_RS03745
uniprot id: C8X0U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

485915:DRET RS12270
gene id: 485915:DRET_RS12270
uniprot id: C8X5N4
names: Similarity
messages: Belongs to the Skp family.

485915:DRET RS06200
gene id: 485915:DRET_RS06200
uniprot id: C8X1V7
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS02405
gene id: 485915:DRET_RS02405
uniprot id: C8X0F6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

485915:DRET RS10225
gene id: 485915:DRET_RS10225
uniprot id: C8X459
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

485915:DRET RS09575
gene id: 485915:DRET_RS09575
uniprot id: C8X4H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

485915:DRET RS03750
gene id: 485915:DRET_RS03750
uniprot id: C8X0U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

485915:DRET RS10420
gene id: 485915:DRET_RS10420
uniprot id: C8X494
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

485915:DRET RS01430
gene id: 485915:DRET_RS01430
uniprot id: C8WZW4
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS08495
gene id: 485915:DRET_RS08495
uniprot id: C8X3J2
names: Similarity
messages: Belongs to the aspartokinase family.

485915:DRET RS03885
gene id: 485915:DRET_RS03885
uniprot id: C8X0W7
names: Cofactor
names: Subunit
messages: Binds 1 FAD per subunit.
messages: Homodimer.

485915:DRET RS09385
gene id: 485915:DRET_RS09385
uniprot id: C8X413
names: Similarity
messages: Belongs to the SfsA family.

485915:DRET RS03765
gene id: 485915:DRET_RS03765
uniprot id: C8X0U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

485915:DRET RS02645
gene id: 485915:DRET_RS02645
uniprot id: C8WYR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

485915:DRET RS05710
gene id: 485915:DRET_RS05710
uniprot id: C8X2A4
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

485915:DRET RS09695
gene id: 485915:DRET_RS09695
uniprot id: C8X4K2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

485915:DRET RS10805
gene id: 485915:DRET_RS10805
uniprot id: C8X4U9
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS13035
gene id: 485915:DRET_RS13035
uniprot id: C8X3E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

485915:DRET RS11335
gene id: 485915:DRET_RS11335
uniprot id: C8X550
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

485915:DRET RS09200
gene id: 485915:DRET_RS09200
uniprot id: C8X3X6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

485915:DRET RS04620
gene id: 485915:DRET_RS04620
uniprot id: C8X1B1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

485915:DRET RS03245
gene id: 485915:DRET_RS03245
uniprot id: C8WZ25
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS08275
gene id: 485915:DRET_RS08275
uniprot id: C8X3E9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

485915:DRET RS05715
gene id: 485915:DRET_RS05715
uniprot id: C8X2A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

485915:DRET RS06860
gene id: 485915:DRET_RS06860
uniprot id: C8X2L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

485915:DRET RS00085
gene id: 485915:DRET_RS00085
uniprot id: C8WZ43
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

485915:DRET RS07735
gene id: 485915:DRET_RS07735
uniprot id: C8X341
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

485915:DRET RS07350
gene id: 485915:DRET_RS07350
uniprot id: C8X2W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

485915:DRET RS03850
gene id: 485915:DRET_RS03850
uniprot id: C8X0W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

485915:DRET RS11240
gene id: 485915:DRET_RS11240
uniprot id: C8X532
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

485915:DRET RS04030
gene id: 485915:DRET_RS04030
uniprot id: C8X0Z3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

485915:DRET RS02795
gene id: 485915:DRET_RS02795
uniprot id: C8WYT9
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS07605
gene id: 485915:DRET_RS07605
uniprot id: C8X312
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

485915:DRET RS04575
gene id: 485915:DRET_RS04575
uniprot id: C8X1A2
names: Similarity
messages: Belongs to the ros/MucR family.

485915:DRET RS10820
gene id: 485915:DRET_RS10820
uniprot id: C8X4V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

485915:DRET RS08745
gene id: 485915:DRET_RS08745
uniprot id: C8X3N2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

485915:DRET RS05425
gene id: 485915:DRET_RS05425
uniprot id: C8X247
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

485915:DRET RS05950
gene id: 485915:DRET_RS05950
uniprot id: C8X1Q4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

485915:DRET RS12045
gene id: 485915:DRET_RS12045
uniprot id: C8X5J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

485915:DRET RS03970
gene id: 485915:DRET_RS03970
uniprot id: C8X0Y3
names: Subcellular Location Annotation
messages: Membrane

485915:DRET RS04590
gene id: 485915:DRET_RS04590
uniprot id: C8X1A5
names: Similarity
messages: Belongs to the sulfatase family.

485915:DRET RS11080
gene id: 485915:DRET_RS11080
uniprot id: C8X501
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

485915:DRET RS11710
gene id: 485915:DRET_RS11710
uniprot id: C8X5C4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

485915:DRET RS02395
gene id: 485915:DRET_RS02395
uniprot id: C8X0F4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

485915:DRET RS01600
gene id: 485915:DRET_RS01600
uniprot id: C8WZZ9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

485915:DRET RS12330
gene id: 485915:DRET_RS12330
uniprot id: C8X5P4
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

485915:DRET RS08370
gene id: 485915:DRET_RS08370
uniprot id: C8X3G8
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

485915:DRET RS00630
gene id: 485915:DRET_RS00630
uniprot id: C8WZF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

485915:DRET RS09775
gene id: 485915:DRET_RS09775
uniprot id: C8X4L8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

485915:DRET RS10525
gene id: 485915:DRET_RS10525
uniprot id: C8X4B4
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

485915:DRET RS03170
gene id: 485915:DRET_RS03170
uniprot id: C8WZ11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

485915:DRET RS08680
gene id: 485915:DRET_RS08680
uniprot id: C8X3M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

485915:DRET RS02035
gene id: 485915:DRET_RS02035
uniprot id: C8X085
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

485915:DRET RS12300
gene id: 485915:DRET_RS12300
uniprot id: C8X5N8
names: Subcellular Location Annotation
messages: Membrane