483547:GSUB RS12590
gene id: 483547:GSUB_RS12590
uniprot id: A0A0B5FIN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

483547:GSUB RS02025
gene id: 483547:GSUB_RS02025
uniprot id: A0A0B5FE86
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

483547:GSUB RS15170
gene id: 483547:GSUB_RS15170
uniprot id: A0A0B5FVL4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

483547:GSUB RS02650
gene id: 483547:GSUB_RS02650
uniprot id: A0A0B5FEF4
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS02260
gene id: 483547:GSUB_RS02260
uniprot id: A0A0B5FEA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

483547:GSUB RS01665
gene id: 483547:GSUB_RS01665
uniprot id: A0A0B5FE51
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the nitrate reductase NapAB complex composed of NapA and NapB.
messages: Heterodimer of a large and a small subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Secreted

483547:GSUB RS09445
gene id: 483547:GSUB_RS09445
uniprot id: A0A0B5FEZ7
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS12770
gene id: 483547:GSUB_RS12770
uniprot id: A0A0B5FIR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

483547:GSUB RS02660
gene id: 483547:GSUB_RS02660
uniprot id: A0A0B5FNS1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

483547:GSUB RS11015
gene id: 483547:GSUB_RS11015
uniprot id: A0A0B5FS66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

483547:GSUB RS07050
gene id: 483547:GSUB_RS07050
uniprot id: A0A0B5FNW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

483547:GSUB RS15555
gene id: 483547:GSUB_RS15555
uniprot id: A0A0B5FHL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

483547:GSUB RS08180
gene id: 483547:GSUB_RS08180
uniprot id: A0A0B5FEK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

483547:GSUB RS10305
gene id: 483547:GSUB_RS10305
uniprot id: A0A0B5FQC9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

483547:GSUB RS03930
gene id: 483547:GSUB_RS03930
uniprot id: A0A0B5FQK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

483547:GSUB RS08245
gene id: 483547:GSUB_RS08245
uniprot id: A0A0B5FPH7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

483547:GSUB RS05920
gene id: 483547:GSUB_RS05920
uniprot id: A0A0B5FNH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

483547:GSUB RS01695
gene id: 483547:GSUB_RS01695
uniprot id: A0A0B5FI33
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

483547:GSUB RS12600
gene id: 483547:GSUB_RS12600
uniprot id: A0A0B5FRG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

483547:GSUB RS03820
gene id: 483547:GSUB_RS03820
uniprot id: A0A0B5FEW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

483547:GSUB RS08780
gene id: 483547:GSUB_RS08780
uniprot id: A0A0B5FSQ0
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

483547:GSUB RS13215
gene id: 483547:GSUB_RS13215
uniprot id: A0A0B5FT40
names: Similarity
messages: Belongs to the GARS family.

483547:GSUB RS10910
gene id: 483547:GSUB_RS10910
uniprot id: A0A0B5FTL0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

483547:GSUB RS03090
gene id: 483547:GSUB_RS03090
uniprot id: A0A0B5FEL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

483547:GSUB RS07755
gene id: 483547:GSUB_RS07755
uniprot id: A0A0B5FP85
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

483547:GSUB RS03940
gene id: 483547:GSUB_RS03940
uniprot id: A0A0B5FCH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS09275
gene id: 483547:GSUB_RS09275
uniprot id: A0A0B5FSW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

483547:GSUB RS10235
gene id: 483547:GSUB_RS10235
uniprot id: A0A0B5FTA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

483547:GSUB RS01820
gene id: 483547:GSUB_RS01820
uniprot id: A0A0B5FPQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

483547:GSUB RS06355
gene id: 483547:GSUB_RS06355
uniprot id: A0A0B5FDL3
names: Subcellular Location Annotation
messages: Cytoplasm

483547:GSUB RS07450
gene id: 483547:GSUB_RS07450
uniprot id: A0A0B5FGG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

483547:GSUB RS13005
gene id: 483547:GSUB_RS13005
uniprot id: A0A0B5FIV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

483547:GSUB RS14065
gene id: 483547:GSUB_RS14065
uniprot id: A0A0B5FTF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

483547:GSUB RS01160
gene id: 483547:GSUB_RS01160
uniprot id: A0A0B5FPC5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

483547:GSUB RS06140
gene id: 483547:GSUB_RS06140
uniprot id: A0A0B5FQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

483547:GSUB RS01415
gene id: 483547:GSUB_RS01415
uniprot id: A0A0B5FLH8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

483547:GSUB RS01520
gene id: 483547:GSUB_RS01520
uniprot id: A0A0B5FE33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

483547:GSUB RS01860
gene id: 483547:GSUB_RS01860
uniprot id: A0A0B5FE70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

483547:GSUB RS09410
gene id: 483547:GSUB_RS09410
uniprot id: A0A0B5FEZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

483547:GSUB RS05780
gene id: 483547:GSUB_RS05780
uniprot id: A0A0B5FQ15
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

483547:GSUB RS12340
gene id: 483547:GSUB_RS12340
uniprot id: A0A0B5FUB2
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

483547:GSUB RS02585
gene id: 483547:GSUB_RS02585
uniprot id: A0A0B5FBX0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

483547:GSUB RS06025
gene id: 483547:GSUB_RS06025
uniprot id: A0A0B5FRK4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

483547:GSUB RS04455
gene id: 483547:GSUB_RS04455
uniprot id: A0A0B5FF82
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

483547:GSUB RS03510
gene id: 483547:GSUB_RS03510
uniprot id: A0A0B5FCB1
names: Similarity
messages: Belongs to the peptidase C56 family.

483547:GSUB RS08150
gene id: 483547:GSUB_RS08150
uniprot id: A0A0B5FSH1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

483547:GSUB RS12085
gene id: 483547:GSUB_RS12085
uniprot id: A0A0B5FG98
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

483547:GSUB RS08860
gene id: 483547:GSUB_RS08860
uniprot id: A0A0B5FSQ9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

483547:GSUB RS13100
gene id: 483547:GSUB_RS13100
uniprot id: A0A0B5FT26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

483547:GSUB RS05595
gene id: 483547:GSUB_RS05595
uniprot id: A0A0B5FDC4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

483547:GSUB RS07190
gene id: 483547:GSUB_RS07190
uniprot id: A0A0B5FNY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

483547:GSUB RS11275
gene id: 483547:GSUB_RS11275
uniprot id: A0A0B5FSD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS04015
gene id: 483547:GSUB_RS04015
uniprot id: A0A0B5FQM4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

483547:GSUB RS01505
gene id: 483547:GSUB_RS01505
uniprot id: A0A0B5FPN1
names: Similarity
messages: Belongs to the catalase family.

483547:GSUB RS11890
gene id: 483547:GSUB_RS11890
uniprot id: A0A0B5FSK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

483547:GSUB RS07905
gene id: 483547:GSUB_RS07905
uniprot id: A0A0B5FPB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

483547:GSUB RS10785
gene id: 483547:GSUB_RS10785
uniprot id: A0A0B5FQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

483547:GSUB RS11945
gene id: 483547:GSUB_RS11945
uniprot id: A0A0B5FR71
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

483547:GSUB RS07670
gene id: 483547:GSUB_RS07670
uniprot id: A0A0B5FQR3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

483547:GSUB RS03995
gene id: 483547:GSUB_RS03995
uniprot id: A0A0B5FCI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

483547:GSUB RS04165
gene id: 483547:GSUB_RS04165
uniprot id: A0A0B5FMP1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

483547:GSUB RS02500
gene id: 483547:GSUB_RS02500
uniprot id: A0A0B5FBV8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

483547:GSUB RS03915
gene id: 483547:GSUB_RS03915
uniprot id: A0A0B5FEX6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

483547:GSUB RS07660
gene id: 483547:GSUB_RS07660
uniprot id: A0A0B5FGJ8
names: Similarity
messages: Belongs to the fabD family.

483547:GSUB RS11995
gene id: 483547:GSUB_RS11995
uniprot id: A0A0B5FU71
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

483547:GSUB RS08375
gene id: 483547:GSUB_RS08375
uniprot id: A0A0B5FSK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

483547:GSUB RS11830
gene id: 483547:GSUB_RS11830
uniprot id: A0A0B5FR49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

483547:GSUB RS10870
gene id: 483547:GSUB_RS10870
uniprot id: A0A0B5FS40
names: Similarity
messages: Belongs to the universal stress protein A family.

483547:GSUB RS02255
gene id: 483547:GSUB_RS02255
uniprot id: A0A0B5FBS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

483547:GSUB RS12520
gene id: 483547:GSUB_RS12520
uniprot id: A0A0B5FRE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

483547:GSUB RS04000
gene id: 483547:GSUB_RS04000
uniprot id: A0A0B5FEZ3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

483547:GSUB RS01525
gene id: 483547:GSUB_RS01525
uniprot id: A0A0B5FLL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

483547:GSUB RS07955
gene id: 483547:GSUB_RS07955
uniprot id: A0A0B5FKP1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

483547:GSUB RS01405
gene id: 483547:GSUB_RS01405
uniprot id: A0A0B5FDY3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

483547:GSUB RS02040
gene id: 483547:GSUB_RS02040
uniprot id: A0A0B5FNL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

483547:GSUB RS07675
gene id: 483547:GSUB_RS07675
uniprot id: A0A0B5FS75
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

483547:GSUB RS07480
gene id: 483547:GSUB_RS07480
uniprot id: A0A0B5FE32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

483547:GSUB RS00575
gene id: 483547:GSUB_RS00575
uniprot id: A0A0B5FDJ5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

483547:GSUB RS15920
gene id: 483547:GSUB_RS15920
uniprot id: A0A0B5FSW0
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

483547:GSUB RS07170
gene id: 483547:GSUB_RS07170
uniprot id: A0A0B5FS08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

483547:GSUB RS11510
gene id: 483547:GSUB_RS11510
uniprot id: A0A0B5FIA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

483547:GSUB RS13655
gene id: 483547:GSUB_RS13655
uniprot id: A0A0B5FUV6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

483547:GSUB RS03415
gene id: 483547:GSUB_RS03415
uniprot id: A0A0B5FQC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

483547:GSUB RS09390
gene id: 483547:GSUB_RS09390
uniprot id: A0A0B5FH60
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

483547:GSUB RS07220
gene id: 483547:GSUB_RS07220
uniprot id: A0A0B5FNZ0
names: Similarity
messages: Belongs to the UPF0047 family.

483547:GSUB RS03290
gene id: 483547:GSUB_RS03290
uniprot id: A0A0B5FI56
names: Similarity
messages: Belongs to the AlaDH/PNT family.

483547:GSUB RS00565
gene id: 483547:GSUB_RS00565
uniprot id: A0A0B5FP38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS16415
gene id: 483547:GSUB_RS16415
uniprot id: A0A0B5FT32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

483547:GSUB RS02145
gene id: 483547:GSUB_RS02145
uniprot id: A0A0B5FPT6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

483547:GSUB RS06885
gene id: 483547:GSUB_RS06885
uniprot id: A0A0B5FDT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

483547:GSUB RS02070
gene id: 483547:GSUB_RS02070
uniprot id: A0A0B5FNL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

483547:GSUB RS04465
gene id: 483547:GSUB_RS04465
uniprot id: A0A0B5FMU7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

483547:GSUB RS01560
gene id: 483547:GSUB_RS01560
uniprot id: A0A0B5FNH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

483547:GSUB RS07460
gene id: 483547:GSUB_RS07460
uniprot id: A0A0B5FQP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

483547:GSUB RS07680
gene id: 483547:GSUB_RS07680
uniprot id: A0A0B5FE60
names: Similarity
messages: Belongs to the LacAB/RpiB family.

483547:GSUB RS17015
gene id: 483547:GSUB_RS17015
uniprot id: A0A0B5FLB6
names: Similarity
messages: Belongs to the HsdR family.

483547:GSUB RS10530
gene id: 483547:GSUB_RS10530
uniprot id: A0A0B5FFH7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS09180
gene id: 483547:GSUB_RS09180
uniprot id: A0A0B5FRC7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

483547:GSUB RS01370
gene id: 483547:GSUB_RS01370
uniprot id: A0A0B5FBE5
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

483547:GSUB RS12530
gene id: 483547:GSUB_RS12530
uniprot id: A0A0B5FUD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

483547:GSUB RS05585
gene id: 483547:GSUB_RS05585
uniprot id: A0A0B5FRE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

483547:GSUB RS12555
gene id: 483547:GSUB_RS12555
uniprot id: A0A0B5FUE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

483547:GSUB RS05570
gene id: 483547:GSUB_RS05570
uniprot id: A0A0B5FNE7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

483547:GSUB RS00130
gene id: 483547:GSUB_RS00130
uniprot id: A0A0B5FDC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

483547:GSUB RS09865
gene id: 483547:GSUB_RS09865
uniprot id: A0A0B5FT52
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

483547:GSUB RS09705
gene id: 483547:GSUB_RS09705
uniprot id: A0A0B5FHA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

483547:GSUB RS00650
gene id: 483547:GSUB_RS00650
uniprot id: A0A0B5FP62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

483547:GSUB RS10425
gene id: 483547:GSUB_RS10425
uniprot id: A0A0B5FFG2
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS00715
gene id: 483547:GSUB_RS00715
uniprot id: A0A0B5FL68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

483547:GSUB RS13245
gene id: 483547:GSUB_RS13245
uniprot id: A0A0B5FUP1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

483547:GSUB RS10835
gene id: 483547:GSUB_RS10835
uniprot id: A0A0B5FHV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

483547:GSUB RS07665
gene id: 483547:GSUB_RS07665
uniprot id: A0A0B5FP72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

483547:GSUB RS10970
gene id: 483547:GSUB_RS10970
uniprot id: A0A0B5FHY3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS11820
gene id: 483547:GSUB_RS11820
uniprot id: A0A0B5FIE9
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

483547:GSUB RS08440
gene id: 483547:GSUB_RS08440
uniprot id: A0A0B5FR45
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

483547:GSUB RS04010
gene id: 483547:GSUB_RS04010
uniprot id: A0A0B5FP71
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

483547:GSUB RS10310
gene id: 483547:GSUB_RS10310
uniprot id: A0A0B5FRU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

483547:GSUB RS13070
gene id: 483547:GSUB_RS13070
uniprot id: A0A0B5FRN1
names: Similarity
messages: Belongs to the UPF0102 family.

483547:GSUB RS10250
gene id: 483547:GSUB_RS10250
uniprot id: A0A0B5FQB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

483547:GSUB RS10845
gene id: 483547:GSUB_RS10845
uniprot id: A0A0B5FS33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

483547:GSUB RS06745
gene id: 483547:GSUB_RS06745
uniprot id: A0A0B5FG54
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

483547:GSUB RS06055
gene id: 483547:GSUB_RS06055
uniprot id: A0A0B5FFU8
names: Similarity
messages: Belongs to the cytochrome c-552 family.

483547:GSUB RS00775
gene id: 483547:GSUB_RS00775
uniprot id: A0A0B5FDN1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

483547:GSUB RS03395
gene id: 483547:GSUB_RS03395
uniprot id: A0A0B5FEQ7
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

483547:GSUB RS03435
gene id: 483547:GSUB_RS03435
uniprot id: A0A0B5FMC9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

483547:GSUB RS06010
gene id: 483547:GSUB_RS06010
uniprot id: A0A0B5FNI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

483547:GSUB RS15755
gene id: 483547:GSUB_RS15755
uniprot id: A0A0B5FVV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS02020
gene id: 483547:GSUB_RS02020
uniprot id: A0A0B5FBQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

483547:GSUB RS04195
gene id: 483547:GSUB_RS04195
uniprot id: A0A0B5FF25
names: Subunit
messages: Heterodimer of a large and a small subunit.

483547:GSUB RS06435
gene id: 483547:GSUB_RS06435
uniprot id: A0A0B5FDM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

483547:GSUB RS14385
gene id: 483547:GSUB_RS14385
uniprot id: A0A0B5FTK1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

483547:GSUB RS14195
gene id: 483547:GSUB_RS14195
uniprot id: A0A0B5FV27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

483547:GSUB RS05850
gene id: 483547:GSUB_RS05850
uniprot id: A0A0B5FNH0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

483547:GSUB RS02045
gene id: 483547:GSUB_RS02045
uniprot id: A0A0B5FPS7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

483547:GSUB RS13065
gene id: 483547:GSUB_RS13065
uniprot id: A0A0B5FIW5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS02330
gene id: 483547:GSUB_RS02330
uniprot id: A0A0B5FEB6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

483547:GSUB RS10810
gene id: 483547:GSUB_RS10810
uniprot id: A0A0B5FQM5
names: Similarity
messages: Belongs to the RecJ family.

483547:GSUB RS16675
gene id: 483547:GSUB_RS16675
uniprot id: A0A0B5FX14
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

483547:GSUB RS10445
gene id: 483547:GSUB_RS10445
uniprot id: A0A0B5FTD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

483547:GSUB RS12685
gene id: 483547:GSUB_RS12685
uniprot id: A0A0B5FUG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

483547:GSUB RS10475
gene id: 483547:GSUB_RS10475
uniprot id: A0A0B5FTE3
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS12660
gene id: 483547:GSUB_RS12660
uniprot id: A0A0B5FIR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

483547:GSUB RS15020
gene id: 483547:GSUB_RS15020
uniprot id: A0A0B5FJR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

483547:GSUB RS00635
gene id: 483547:GSUB_RS00635
uniprot id: A0A0B5FDK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

483547:GSUB RS03505
gene id: 483547:GSUB_RS03505
uniprot id: A0A0B5FQD8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

483547:GSUB RS06855
gene id: 483547:GSUB_RS06855
uniprot id: A0A0B5FG68
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

483547:GSUB RS03030
gene id: 483547:GSUB_RS03030
uniprot id: A0A0B5FM74
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

483547:GSUB RS15500
gene id: 483547:GSUB_RS15500
uniprot id: A0A0B5FJW9
names: Similarity
messages: Belongs to the archease family.

483547:GSUB RS04915
gene id: 483547:GSUB_RS04915
uniprot id: A0A0B5FFI3
names: Similarity
messages: Belongs to the PilY1 family.

483547:GSUB RS09500
gene id: 483547:GSUB_RS09500
uniprot id: A0A0B5FF05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

483547:GSUB RS14145
gene id: 483547:GSUB_RS14145
uniprot id: A0A0B5FH29
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

483547:GSUB RS11740
gene id: 483547:GSUB_RS11740
uniprot id: A0A0B5FID7
names: Subcellular Location Annotation
messages: Cytoplasm

483547:GSUB RS12400
gene id: 483547:GSUB_RS12400
uniprot id: A0A0B5FSR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

483547:GSUB RS17255
gene id: 483547:GSUB_RS17255
uniprot id: A0A0B5FXK6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

483547:GSUB RS08665
gene id: 483547:GSUB_RS08665
uniprot id: A0A0B5FR64
names: Similarity
messages: Belongs to the VapB family.

483547:GSUB RS16460
gene id: 483547:GSUB_RS16460
uniprot id: A0A0B5FTU0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

483547:GSUB RS04420
gene id: 483547:GSUB_RS04420
uniprot id: A0A0B5FCQ3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

483547:GSUB RS11050
gene id: 483547:GSUB_RS11050
uniprot id: A0A0B5FS68
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

483547:GSUB RS07700
gene id: 483547:GSUB_RS07700
uniprot id: A0A0B5FS79
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

483547:GSUB RS10975
gene id: 483547:GSUB_RS10975
uniprot id: A0A0B5FQQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

483547:GSUB RS08115
gene id: 483547:GSUB_RS08115
uniprot id: A0A0B5FPF4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

483547:GSUB RS03085
gene id: 483547:GSUB_RS03085
uniprot id: A0A0B5FC54
names: Similarity
messages: Belongs to the GSP E family.

483547:GSUB RS09385
gene id: 483547:GSUB_RS09385
uniprot id: A0A0B5FEY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

483547:GSUB RS04470
gene id: 483547:GSUB_RS04470
uniprot id: A0A0B5FPE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS06980
gene id: 483547:GSUB_RS06980
uniprot id: A0A0B5FG90
names: Similarity
messages: Belongs to the RutC family.

483547:GSUB RS10950
gene id: 483547:GSUB_RS10950
uniprot id: A0A0B5FQQ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS14830
gene id: 483547:GSUB_RS14830
uniprot id: A0A0B5FHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

483547:GSUB RS17310
gene id: 483547:GSUB_RS17310
uniprot id: A0A0B5FLE8
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS03245
gene id: 483547:GSUB_RS03245
uniprot id: A0A0B5FNZ8
names: Function
names: Similarity
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.

483547:GSUB RS13765
gene id: 483547:GSUB_RS13765
uniprot id: A0A0B5FRY6
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

483547:GSUB RS05900
gene id: 483547:GSUB_RS05900
uniprot id: A0A0B5FQ26
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

483547:GSUB RS03925
gene id: 483547:GSUB_RS03925
uniprot id: A0A0B5FP63
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

483547:GSUB RS13110
gene id: 483547:GSUB_RS13110
uniprot id: A0A0B5FGM4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

483547:GSUB RS13325
gene id: 483547:GSUB_RS13325
uniprot id: A0A0B5FGP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

483547:GSUB RS03880
gene id: 483547:GSUB_RS03880
uniprot id: A0A0B5FCG6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS10415
gene id: 483547:GSUB_RS10415
uniprot id: A0A0B5FRV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

483547:GSUB RS00620
gene id: 483547:GSUB_RS00620
uniprot id: A0A0B5FN16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

483547:GSUB RS12215
gene id: 483547:GSUB_RS12215
uniprot id: A0A0B5FGA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS11270
gene id: 483547:GSUB_RS11270
uniprot id: A0A0B5FQY9
names: Similarity
messages: Belongs to the universal stress protein A family.

483547:GSUB RS13500
gene id: 483547:GSUB_RS13500
uniprot id: A0A0B5FRU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

483547:GSUB RS14525
gene id: 483547:GSUB_RS14525
uniprot id: A0A0B5FSA9
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

483547:GSUB RS02850
gene id: 483547:GSUB_RS02850
uniprot id: A0A0B5FQ47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved Asp active site.

483547:GSUB RS12650
gene id: 483547:GSUB_RS12650
uniprot id: A0A0B5FRG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

483547:GSUB RS11955
gene id: 483547:GSUB_RS11955
uniprot id: A0A0B5FSK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

483547:GSUB RS16280
gene id: 483547:GSUB_RS16280
uniprot id: A0A0B5FUM9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

483547:GSUB RS14260
gene id: 483547:GSUB_RS14260
uniprot id: A0A0B5FJE4
names: Subcellular Location Annotation
messages: Periplasm

483547:GSUB RS00310
gene id: 483547:GSUB_RS00310
uniprot id: A0A0B5FT46
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

483547:GSUB RS11175
gene id: 483547:GSUB_RS11175
uniprot id: A0A0B5FFW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

483547:GSUB RS05130
gene id: 483547:GSUB_RS05130
uniprot id: A0A0B5FPU4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

483547:GSUB RS06255
gene id: 483547:GSUB_RS06255
uniprot id: A0A0B5FNL6
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

483547:GSUB RS01605
gene id: 483547:GSUB_RS01605
uniprot id: A0A0B5FBL1
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

483547:GSUB RS12710
gene id: 483547:GSUB_RS12710
uniprot id: A0A0B5FUG9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

483547:GSUB RS06015
gene id: 483547:GSUB_RS06015
uniprot id: A0A0B5FQ42
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

483547:GSUB RS09400
gene id: 483547:GSUB_RS09400
uniprot id: A0A0B5FRF0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

483547:GSUB RS07020
gene id: 483547:GSUB_RS07020
uniprot id: A0A0B5FG95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS00070
gene id: 483547:GSUB_RS00070
uniprot id: A0A0B5FMV2
names: Similarity
messages: Belongs to the pyruvate kinase family.

483547:GSUB RS02800
gene id: 483547:GSUB_RS02800
uniprot id: A0A0B5FEH2
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

483547:GSUB RS00345
gene id: 483547:GSUB_RS00345
uniprot id: A0A0B5FDF8
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS05620
gene id: 483547:GSUB_RS05620
uniprot id: A0A0B5FDC9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

483547:GSUB RS12655
gene id: 483547:GSUB_RS12655
uniprot id: A0A0B5FSV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

483547:GSUB RS10765
gene id: 483547:GSUB_RS10765
uniprot id: A0A0B5FS17
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

483547:GSUB RS03050
gene id: 483547:GSUB_RS03050
uniprot id: A0A0B5FC49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

483547:GSUB RS02495
gene id: 483547:GSUB_RS02495
uniprot id: A0A0B5FPY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

483547:GSUB RS08880
gene id: 483547:GSUB_RS08880
uniprot id: A0A0B5FR89
names: Similarity
messages: Belongs to the P(II) protein family.

483547:GSUB RS03865
gene id: 483547:GSUB_RS03865
uniprot id: A0A0B5FP58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

483547:GSUB RS12635
gene id: 483547:GSUB_RS12635
uniprot id: A0A0B5FUF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

483547:GSUB RS01770
gene id: 483547:GSUB_RS01770
uniprot id: A0A0B5FE58
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS03025
gene id: 483547:GSUB_RS03025
uniprot id: A0A0B5FW91
names: Similarity
messages: Belongs to the Nudix hydrolase family.

483547:GSUB RS07135
gene id: 483547:GSUB_RS07135
uniprot id: A0A0B5FS04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

483547:GSUB RS09150
gene id: 483547:GSUB_RS09150
uniprot id: A0A0B5FPT7
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

483547:GSUB RS00355
gene id: 483547:GSUB_RS00355
uniprot id: A0A0B5FMX9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

483547:GSUB RS06970
gene id: 483547:GSUB_RS06970
uniprot id: A0A0B5FRX9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

483547:GSUB RS06325
gene id: 483547:GSUB_RS06325
uniprot id: A0A0B5FDK9
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS00075
gene id: 483547:GSUB_RS00075
uniprot id: A0A0B5FNV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

483547:GSUB RS10685
gene id: 483547:GSUB_RS10685
uniprot id: A0A0B5FFK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

483547:GSUB RS15675
gene id: 483547:GSUB_RS15675
uniprot id: A0A0B5FHN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

483547:GSUB RS09265
gene id: 483547:GSUB_RS09265
uniprot id: A0A0B5FPV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

483547:GSUB RS12125
gene id: 483547:GSUB_RS12125
uniprot id: A0A0B5FR97
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

483547:GSUB RS12495
gene id: 483547:GSUB_RS12495
uniprot id: A0A0B5FST0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS02440
gene id: 483547:GSUB_RS02440
uniprot id: A0A0B5FPX9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

483547:GSUB RS09475
gene id: 483547:GSUB_RS09475
uniprot id: A0A0B5FH71
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

483547:GSUB RS14590
gene id: 483547:GSUB_RS14590
uniprot id: A0A0B5FVC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

483547:GSUB RS02970
gene id: 483547:GSUB_RS02970
uniprot id: A0A0B5FEJ7
names: Similarity
messages: Belongs to the hemerythrin family.

483547:GSUB RS15105
gene id: 483547:GSUB_RS15105
uniprot id: A0A0B5FHE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

483547:GSUB RS12780
gene id: 483547:GSUB_RS12780
uniprot id: A0A0B5FSX7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS12075
gene id: 483547:GSUB_RS12075
uniprot id: A0A0B5FSM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

483547:GSUB RS09240
gene id: 483547:GSUB_RS09240
uniprot id: A0A0B5FPU5
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

483547:GSUB RS10645
gene id: 483547:GSUB_RS10645
uniprot id: A0A0B5FRZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

483547:GSUB RS00695
gene id: 483547:GSUB_RS00695
uniprot id: A0A0B5FN29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

483547:GSUB RS13690
gene id: 483547:GSUB_RS13690
uniprot id: A0A0B5FGW7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

483547:GSUB RS13900
gene id: 483547:GSUB_RS13900
uniprot id: A0A0B5FUZ6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

483547:GSUB RS15400
gene id: 483547:GSUB_RS15400
uniprot id: A0A0B5FSM4
names: Similarity
messages: Belongs to the HepT RNase toxin family.

483547:GSUB RS06760
gene id: 483547:GSUB_RS06760
uniprot id: A0A0B5FRV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

483547:GSUB RS00985
gene id: 483547:GSUB_RS00985
uniprot id: A0A0B5FN69
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

483547:GSUB RS07465
gene id: 483547:GSUB_RS07465
uniprot id: A0A0B5FKM7
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

483547:GSUB RS00430
gene id: 483547:GSUB_RS00430
uniprot id: A0A0B5FL08
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

483547:GSUB RS12260
gene id: 483547:GSUB_RS12260
uniprot id: A0A0B5FSP5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

483547:GSUB RS00105
gene id: 483547:GSUB_RS00105
uniprot id: A0A0B5FMV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TolB family.
messages: Periplasm

483547:GSUB RS00670
gene id: 483547:GSUB_RS00670
uniprot id: A0A0B5FN25
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

483547:GSUB RS03155
gene id: 483547:GSUB_RS03155
uniprot id: A0A0B5FQ96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

483547:GSUB RS10735
gene id: 483547:GSUB_RS10735
uniprot id: A0A0B5FS13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

483547:GSUB RS14865
gene id: 483547:GSUB_RS14865
uniprot id: A0A0B5FSF0
names: Similarity
messages: Belongs to the FlgM family.

483547:GSUB RS12345
gene id: 483547:GSUB_RS12345
uniprot id: A0A0B5FGC4
names: Similarity
messages: Belongs to the aspartokinase family.

483547:GSUB RS17655
gene id: 483547:GSUB_RS17655
uniprot id: A0A0B5FXK6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

483547:GSUB RS00470
gene id: 483547:GSUB_RS00470
uniprot id: A0A0B5FB23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS01540
gene id: 483547:GSUB_RS01540
uniprot id: A0A0B5FBK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

483547:GSUB RS01930
gene id: 483547:GSUB_RS01930
uniprot id: A0A0B5FPR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

483547:GSUB RS12055
gene id: 483547:GSUB_RS12055
uniprot id: A0A0B5FG93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

483547:GSUB RS02150
gene id: 483547:GSUB_RS02150
uniprot id: A0A0B5FBR8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

483547:GSUB RS06060
gene id: 483547:GSUB_RS06060
uniprot id: A0A0B5FNJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

483547:GSUB RS12670
gene id: 483547:GSUB_RS12670
uniprot id: A0A0B5FIQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

483547:GSUB RS00630
gene id: 483547:GSUB_RS00630
uniprot id: A0A0B5FB48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

483547:GSUB RS09185
gene id: 483547:GSUB_RS09185
uniprot id: A0A0B5FSV4
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

483547:GSUB RS04985
gene id: 483547:GSUB_RS04985
uniprot id: A0A0B5FPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

483547:GSUB RS10680
gene id: 483547:GSUB_RS10680
uniprot id: A0A0B5FTH1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

483547:GSUB RS07645
gene id: 483547:GSUB_RS07645
uniprot id: A0A0B5FS70
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

483547:GSUB RS10560
gene id: 483547:GSUB_RS10560
uniprot id: A0A0B5FFI2
names: Subcellular Location Annotation
messages: Cytoplasm

483547:GSUB RS08290
gene id: 483547:GSUB_RS08290
uniprot id: A0A0B5FGV5
names: Similarity
messages: Belongs to the YoeB family.

483547:GSUB RS06915
gene id: 483547:GSUB_RS06915
uniprot id: A0A0B5FDU4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

483547:GSUB RS08295
gene id: 483547:GSUB_RS08295
uniprot id: A0A0B5FPI6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

483547:GSUB RS04175
gene id: 483547:GSUB_RS04175
uniprot id: A0A0B5FP99
names: Similarity
messages: Belongs to the peptidase M16 family.

483547:GSUB RS00475
gene id: 483547:GSUB_RS00475
uniprot id: A0A0B5FDI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

483547:GSUB RS13730
gene id: 483547:GSUB_RS13730
uniprot id: A0A0B5FRY0
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS12835
gene id: 483547:GSUB_RS12835
uniprot id: A0A0B5FIS9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

483547:GSUB RS02290
gene id: 483547:GSUB_RS02290
uniprot id: A0A0B5FPV4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS01440
gene id: 483547:GSUB_RS01440
uniprot id: A0A0B5FDZ2
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

483547:GSUB RS15940
gene id: 483547:GSUB_RS15940
uniprot id: A0A0B5FK24
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

483547:GSUB RS02520
gene id: 483547:GSUB_RS02520
uniprot id: A0A0B5FPZ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

483547:GSUB RS04670
gene id: 483547:GSUB_RS04670
uniprot id: A0A0B5FMY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

483547:GSUB RS05095
gene id: 483547:GSUB_RS05095
uniprot id: A0A0B5FFL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

483547:GSUB RS15850
gene id: 483547:GSUB_RS15850
uniprot id: A0A0B5FK08
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

483547:GSUB RS08210
gene id: 483547:GSUB_RS08210
uniprot id: A0A0B5FGU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

483547:GSUB RS13600
gene id: 483547:GSUB_RS13600
uniprot id: A0A0B5FGU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

483547:GSUB RS07745
gene id: 483547:GSUB_RS07745
uniprot id: A0A0B5FE68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

483547:GSUB RS14550
gene id: 483547:GSUB_RS14550
uniprot id: A0A0B5FJK5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS12990
gene id: 483547:GSUB_RS12990
uniprot id: A0A0B5FT08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS09615
gene id: 483547:GSUB_RS09615
uniprot id: A0A0B5FF15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

483547:GSUB RS13465
gene id: 483547:GSUB_RS13465
uniprot id: A0A0B5FJ35
names: Similarity
messages: Belongs to the glutamate synthase family.

483547:GSUB RS06145
gene id: 483547:GSUB_RS06145
uniprot id: A0A0B5FRL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

483547:GSUB RS02995
gene id: 483547:GSUB_RS02995
uniprot id: A0A0B5FEK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

483547:GSUB RS04405
gene id: 483547:GSUB_RS04405
uniprot id: A0A0B5FMT2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

483547:GSUB RS05610
gene id: 483547:GSUB_RS05610
uniprot id: A0A0B5FQ02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

483547:GSUB RS06975
gene id: 483547:GSUB_RS06975
uniprot id: A0A0B5FDV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

483547:GSUB RS06195
gene id: 483547:GSUB_RS06195
uniprot id: A0A0B5FNK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

483547:GSUB RS12885
gene id: 483547:GSUB_RS12885
uniprot id: A0A0B5FSZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

483547:GSUB RS09085
gene id: 483547:GSUB_RS09085
uniprot id: A0A0B5FEU7
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

483547:GSUB RS06420
gene id: 483547:GSUB_RS06420
uniprot id: A0A0B5FQA2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

483547:GSUB RS04620
gene id: 483547:GSUB_RS04620
uniprot id: A0A0B5FPH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

483547:GSUB RS11400
gene id: 483547:GSUB_RS11400
uniprot id: A0A0B5FR01
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS04740
gene id: 483547:GSUB_RS04740
uniprot id: A0A0B5FMZ9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS05785
gene id: 483547:GSUB_RS05785
uniprot id: A0A0B5FRH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS13010
gene id: 483547:GSUB_RS13010
uniprot id: A0A0B5FRM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

483547:GSUB RS07365
gene id: 483547:GSUB_RS07365
uniprot id: A0A0B5FS35
names: Subcellular Location Annotation
messages: Cytoplasm

483547:GSUB RS05680
gene id: 483547:GSUB_RS05680
uniprot id: A0A0B5FDE1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

483547:GSUB RS10290
gene id: 483547:GSUB_RS10290
uniprot id: A0A0B5FTB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

483547:GSUB RS02975
gene id: 483547:GSUB_RS02975
uniprot id: A0A0B5FM65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

483547:GSUB RS13565
gene id: 483547:GSUB_RS13565
uniprot id: A0A0B5FT89
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

483547:GSUB RS12890
gene id: 483547:GSUB_RS12890
uniprot id: A0A0B5FUJ0
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

483547:GSUB RS14985
gene id: 483547:GSUB_RS14985
uniprot id: A0A0B5FJR2
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

483547:GSUB RS00505
gene id: 483547:GSUB_RS00505
uniprot id: A0A0B5FDI7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

483547:GSUB RS14305
gene id: 483547:GSUB_RS14305
uniprot id: A0A0B5FJE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

483547:GSUB RS04300
gene id: 483547:GSUB_RS04300
uniprot id: A0A0B5FCN5
names: Similarity
messages: Belongs to the AOR/FOR family.

483547:GSUB RS07130
gene id: 483547:GSUB_RS07130
uniprot id: A0A0B5FQJ0
names: Similarity
messages: Belongs to the MEMO1 family.

483547:GSUB RS12550
gene id: 483547:GSUB_RS12550
uniprot id: A0A0B5FST9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

483547:GSUB RS15035
gene id: 483547:GSUB_RS15035
uniprot id: A0A0B5FVJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

483547:GSUB RS13240
gene id: 483547:GSUB_RS13240
uniprot id: A0A0B5FT44
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

483547:GSUB RS02545
gene id: 483547:GSUB_RS02545
uniprot id: A0A0B5FPZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

483547:GSUB RS02540
gene id: 483547:GSUB_RS02540
uniprot id: A0A0B5FNR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

483547:GSUB RS11870
gene id: 483547:GSUB_RS11870
uniprot id: A0A0B5FU52
names: Caution
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS15120
gene id: 483547:GSUB_RS15120
uniprot id: A0A0B5FJS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraY family.
messages: Cytoplasm

483547:GSUB RS08300
gene id: 483547:GSUB_RS08300
uniprot id: A0A0B5FR31
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

483547:GSUB RS11000
gene id: 483547:GSUB_RS11000
uniprot id: A0A0B5FHZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

483547:GSUB RS05230
gene id: 483547:GSUB_RS05230
uniprot id: A0A0B5FPV6
names: Similarity
messages: Belongs to the AOR/FOR family.

483547:GSUB RS10865
gene id: 483547:GSUB_RS10865
uniprot id: A0A0B5FQN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

483547:GSUB RS09805
gene id: 483547:GSUB_RS09805
uniprot id: A0A0B5FUM9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

483547:GSUB RS14515
gene id: 483547:GSUB_RS14515
uniprot id: A0A0B5FH72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

483547:GSUB RS01465
gene id: 483547:GSUB_RS01465
uniprot id: A0A0B5FDZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

483547:GSUB RS03725
gene id: 483547:GSUB_RS03725
uniprot id: A0A0B5FEU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

483547:GSUB RS04020
gene id: 483547:GSUB_RS04020
uniprot id: A0A0B5FCJ0
names: Similarity
messages: Belongs to the UPF0166 family.

483547:GSUB RS12365
gene id: 483547:GSUB_RS12365
uniprot id: A0A0B5FUB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

483547:GSUB RS00840
gene id: 483547:GSUB_RS00840
uniprot id: A0A0B5FDP1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS00615
gene id: 483547:GSUB_RS00615
uniprot id: A0A0B5FL44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS01565
gene id: 483547:GSUB_RS01565
uniprot id: A0A0B5FPN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

483547:GSUB RS12645
gene id: 483547:GSUB_RS12645
uniprot id: A0A0B5FIP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

483547:GSUB RS04660
gene id: 483547:GSUB_RS04660
uniprot id: A0A0B5FCT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

483547:GSUB RS16690
gene id: 483547:GSUB_RS16690
uniprot id: A0A0B5FL72
names: Similarity
messages: Belongs to the RecJ family.

483547:GSUB RS02410
gene id: 483547:GSUB_RS02410
uniprot id: A0A0B5FPX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

483547:GSUB RS00550
gene id: 483547:GSUB_RS00550
uniprot id: A0A0B5FN08
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

483547:GSUB RS00340
gene id: 483547:GSUB_RS00340
uniprot id: A0A0B5FAZ3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

483547:GSUB RS10790
gene id: 483547:GSUB_RS10790
uniprot id: A0A0B5FS21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

483547:GSUB RS14175
gene id: 483547:GSUB_RS14175
uniprot id: A0A0B5FJC8
names: Similarity
messages: Belongs to the HypE family.

483547:GSUB RS02140
gene id: 483547:GSUB_RS02140
uniprot id: A0A0B5FNM2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

483547:GSUB RS03985
gene id: 483547:GSUB_RS03985
uniprot id: A0A0B5FP67
names: Similarity
messages: Belongs to the UPF0047 family.

483547:GSUB RS08205
gene id: 483547:GSUB_RS08205
uniprot id: A0A0B5FEL0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

483547:GSUB RS09545
gene id: 483547:GSUB_RS09545
uniprot id: A0A0B5FPY9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

483547:GSUB RS12715
gene id: 483547:GSUB_RS12715
uniprot id: A0A0B5FGJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

483547:GSUB RS04430
gene id: 483547:GSUB_RS04430
uniprot id: A0A0B5FMT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS03460
gene id: 483547:GSUB_RS03460
uniprot id: A0A0B5FQD3
names: Similarity
messages: Belongs to the Smg family.

483547:GSUB RS09590
gene id: 483547:GSUB_RS09590
uniprot id: A0A0B5FH84
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

483547:GSUB RS10860
gene id: 483547:GSUB_RS10860
uniprot id: A0A0B5FHW3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

483547:GSUB RS01660
gene id: 483547:GSUB_RS01660
uniprot id: A0A0B5FBM0
names: Subcellular Location Annotation
messages: Cytoplasm

483547:GSUB RS12695
gene id: 483547:GSUB_RS12695
uniprot id: A0A0B5FIQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

483547:GSUB RS01835
gene id: 483547:GSUB_RS01835
uniprot id: A0A0B5FLQ9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

483547:GSUB RS07845
gene id: 483547:GSUB_RS07845
uniprot id: A0A0B5FPA0
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS16340
gene id: 483547:GSUB_RS16340
uniprot id: A0A0B5FK69
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS14925
gene id: 483547:GSUB_RS14925
uniprot id: A0A0B5FSG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

483547:GSUB RS14970
gene id: 483547:GSUB_RS14970
uniprot id: A0A0B5FTT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

483547:GSUB RS03650
gene id: 483547:GSUB_RS03650
uniprot id: A0A0B5FMF7
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

483547:GSUB RS12610
gene id: 483547:GSUB_RS12610
uniprot id: A0A0B5FUF1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

483547:GSUB RS07685
gene id: 483547:GSUB_RS07685
uniprot id: A0A0B5FGK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS05745
gene id: 483547:GSUB_RS05745
uniprot id: A0A0B5FWE8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

483547:GSUB RS04250
gene id: 483547:GSUB_RS04250
uniprot id: A0A0B5FPB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

483547:GSUB RS01010
gene id: 483547:GSUB_RS01010
uniprot id: A0A0B5FLB8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

483547:GSUB RS07770
gene id: 483547:GSUB_RS07770
uniprot id: A0A0B5FE73
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

483547:GSUB RS03565
gene id: 483547:GSUB_RS03565
uniprot id: A0A0B5FQF1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

483547:GSUB RS08260
gene id: 483547:GSUB_RS08260
uniprot id: A0A0B5FEL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

483547:GSUB RS12320
gene id: 483547:GSUB_RS12320
uniprot id: A0A0B5FIK8
names: Similarity
messages: Belongs to the peptidase S16 family.

483547:GSUB RS17150
gene id: 483547:GSUB_RS17150
uniprot id: A0A0B5FUK4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

483547:GSUB RS00645
gene id: 483547:GSUB_RS00645
uniprot id: A0A0B5FN21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

483547:GSUB RS11105
gene id: 483547:GSUB_RS11105
uniprot id: A0A0B5FQT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

483547:GSUB RS01305
gene id: 483547:GSUB_RS01305
uniprot id: A0A0B5FNB5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

483547:GSUB RS11420
gene id: 483547:GSUB_RS11420
uniprot id: A0A0B5FG04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

483547:GSUB RS09320
gene id: 483547:GSUB_RS09320
uniprot id: A0A0B5FH49
names: Subcellular Location Annotation
messages: Nucleus

483547:GSUB RS04715
gene id: 483547:GSUB_RS04715
uniprot id: A0A0B5FQY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

483547:GSUB RS02320
gene id: 483547:GSUB_RS02320
uniprot id: A0A0B5FPV9
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS12680
gene id: 483547:GSUB_RS12680
uniprot id: A0A0B5FSW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

483547:GSUB RS10260
gene id: 483547:GSUB_RS10260
uniprot id: A0A0B5FTB3
names: Similarity
messages: Belongs to the creatininase superfamily.

483547:GSUB RS14130
gene id: 483547:GSUB_RS14130
uniprot id: A0A0B5FV21
names: Subunit
messages: Heterodimer of a large and a small subunit.

483547:GSUB RS14935
gene id: 483547:GSUB_RS14935
uniprot id: A0A0B5FTS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

483547:GSUB RS06740
gene id: 483547:GSUB_RS06740
uniprot id: A0A0B5FDR4
names: Similarity
messages: Belongs to the threonine synthase family.

483547:GSUB RS12975
gene id: 483547:GSUB_RS12975
uniprot id: A0A0B5FGL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

483547:GSUB RS10770
gene id: 483547:GSUB_RS10770
uniprot id: A0A0B5FTJ0
names: Similarity
messages: Belongs to the peptidase S49 family.

483547:GSUB RS02250
gene id: 483547:GSUB_RS02250
uniprot id: A0A0B5FPV1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

483547:GSUB RS08240
gene id: 483547:GSUB_RS08240
uniprot id: A0A0B5FGU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS17495
gene id: 483547:GSUB_RS17495
uniprot id: A0A0B5FXF3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

483547:GSUB RS02030
gene id: 483547:GSUB_RS02030
uniprot id: A0A0B5FLT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

483547:GSUB RS10920
gene id: 483547:GSUB_RS10920
uniprot id: A0A0B5FHX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

483547:GSUB RS02615
gene id: 483547:GSUB_RS02615
uniprot id: A0A0B5FBX5
names: Similarity
messages: Belongs to the universal stress protein A family.

483547:GSUB RS14040
gene id: 483547:GSUB_RS14040
uniprot id: A0A0B5FV13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

483547:GSUB RS06675
gene id: 483547:GSUB_RS06675
uniprot id: A0A0B5FUM9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

483547:GSUB RS11685
gene id: 483547:GSUB_RS11685
uniprot id: A0A0B5FSG9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

483547:GSUB RS13060
gene id: 483547:GSUB_RS13060
uniprot id: A0A0B5FGL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

483547:GSUB RS01830
gene id: 483547:GSUB_RS01830
uniprot id: A0A0B5FE66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

483547:GSUB RS13025
gene id: 483547:GSUB_RS13025
uniprot id: A0A0B5FT13
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS07500
gene id: 483547:GSUB_RS07500
uniprot id: A0A0B5FP33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

483547:GSUB RS03545
gene id: 483547:GSUB_RS03545
uniprot id: A0A0B5FME7
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

483547:GSUB RS13170
gene id: 483547:GSUB_RS13170
uniprot id: A0A0B5FUM9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

483547:GSUB RS15670
gene id: 483547:GSUB_RS15670
uniprot id: A0A0B5FVU1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

483547:GSUB RS12100
gene id: 483547:GSUB_RS12100
uniprot id: A0A0B5FSN2
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

483547:GSUB RS04435
gene id: 483547:GSUB_RS04435
uniprot id: A0A0B5FPD6
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

483547:GSUB RS12045
gene id: 483547:GSUB_RS12045
uniprot id: A0A0B5FSM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS05440
gene id: 483547:GSUB_RS05440
uniprot id: A0A0B5FND3
names: Similarity
messages: Belongs to the VgrG protein family.

483547:GSUB RS01475
gene id: 483547:GSUB_RS01475
uniprot id: A0A0B5FNE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

483547:GSUB RS09855
gene id: 483547:GSUB_RS09855
uniprot id: A0A0B5FQ49
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS04500
gene id: 483547:GSUB_RS04500
uniprot id: A0A0B5FPE9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

483547:GSUB RS03620
gene id: 483547:GSUB_RS03620
uniprot id: A0A0B5FCC6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

483547:GSUB RS10585
gene id: 483547:GSUB_RS10585
uniprot id: A0A0B5FTF7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

483547:GSUB RS15570
gene id: 483547:GSUB_RS15570
uniprot id: A0A0B5FSQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

483547:GSUB RS05495
gene id: 483547:GSUB_RS05495
uniprot id: A0A0B5FFP5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

483547:GSUB RS00140
gene id: 483547:GSUB_RS00140
uniprot id: A0A0B5FMV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

483547:GSUB RS12355
gene id: 483547:GSUB_RS12355
uniprot id: A0A0B5FRC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

483547:GSUB RS07970
gene id: 483547:GSUB_RS07970
uniprot id: A0A0B5FPC4
names: Similarity
messages: Belongs to the YoeB family.

483547:GSUB RS10600
gene id: 483547:GSUB_RS10600
uniprot id: A0A0B5FFI6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

483547:GSUB RS07600
gene id: 483547:GSUB_RS07600
uniprot id: A0A0B5FP56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

483547:GSUB RS15015
gene id: 483547:GSUB_RS15015
uniprot id: A0A0B5FHD3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

483547:GSUB RS00265
gene id: 483547:GSUB_RS00265
uniprot id: A0A0B5FNX9
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS12970
gene id: 483547:GSUB_RS12970
uniprot id: A0A0B5FV45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

483547:GSUB RS00015
gene id: 483547:GSUB_RS00015
uniprot id: A0A0B5FKU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

483547:GSUB RS15025
gene id: 483547:GSUB_RS15025
uniprot id: A0A0B5FSH3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

483547:GSUB RS10270
gene id: 483547:GSUB_RS10270
uniprot id: A0A0B5FHL9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

483547:GSUB RS14165
gene id: 483547:GSUB_RS14165
uniprot id: A0A0B5FV25
names: Similarity
messages: Belongs to the HupF/HypC family.

483547:GSUB RS15060
gene id: 483547:GSUB_RS15060
uniprot id: A0A0B5FTU4
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

483547:GSUB RS06765
gene id: 483547:GSUB_RS06765
uniprot id: A0A0B5FDR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

483547:GSUB RS04395
gene id: 483547:GSUB_RS04395
uniprot id: A0A0B5FF70
names: Similarity
messages: Belongs to the UPF0178 family.

483547:GSUB RS11305
gene id: 483547:GSUB_RS11305
uniprot id: A0A0B5FTW7
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS02435
gene id: 483547:GSUB_RS02435
uniprot id: A0A0B5FNP7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

483547:GSUB RS05080
gene id: 483547:GSUB_RS05080
uniprot id: A0A0B5FPT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

483547:GSUB RS11700
gene id: 483547:GSUB_RS11700
uniprot id: A0A0B5FG41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

483547:GSUB RS13905
gene id: 483547:GSUB_RS13905
uniprot id: A0A0B5FH09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

483547:GSUB RS01310
gene id: 483547:GSUB_RS01310
uniprot id: A0A0B5FPE5
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

483547:GSUB RS03540
gene id: 483547:GSUB_RS03540
uniprot id: A0A0B5FES5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

483547:GSUB RS15830
gene id: 483547:GSUB_RS15830
uniprot id: A0A0B5FU78
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

483547:GSUB RS13645
gene id: 483547:GSUB_RS13645
uniprot id: A0A0B5FTA0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

483547:GSUB RS15955
gene id: 483547:GSUB_RS15955
uniprot id: A0A0B5FUA1
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

483547:GSUB RS15480
gene id: 483547:GSUB_RS15480
uniprot id: A0A0B5FSP0
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

483547:GSUB RS06260
gene id: 483547:GSUB_RS06260
uniprot id: A0A0B5FQ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

483547:GSUB RS01900
gene id: 483547:GSUB_RS01900
uniprot id: A0A0B5FLR7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

483547:GSUB RS02675
gene id: 483547:GSUB_RS02675
uniprot id: A0A0B5FBY8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

483547:GSUB RS01620
gene id: 483547:GSUB_RS01620
uniprot id: A0A0B5FLN2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

483547:GSUB RS02525
gene id: 483547:GSUB_RS02525
uniprot id: A0A0B5FBW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

483547:GSUB RS07965
gene id: 483547:GSUB_RS07965
uniprot id: A0A0B5FGR3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

483547:GSUB RS12640
gene id: 483547:GSUB_RS12640
uniprot id: A0A0B5FGH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

483547:GSUB RS14535
gene id: 483547:GSUB_RS14535
uniprot id: A0A0B5FTP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

483547:GSUB RS12565
gene id: 483547:GSUB_RS12565
uniprot id: A0A0B5FIN2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

483547:GSUB RS12545
gene id: 483547:GSUB_RS12545
uniprot id: A0A0B5FRE7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

483547:GSUB RS10925
gene id: 483547:GSUB_RS10925
uniprot id: A0A0B5FQP8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

483547:GSUB RS09105
gene id: 483547:GSUB_RS09105
uniprot id: A0A0B5FSU1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

483547:GSUB RS12380
gene id: 483547:GSUB_RS12380
uniprot id: A0A0B5FKZ0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

483547:GSUB RS12985
gene id: 483547:GSUB_RS12985
uniprot id: A0A0B5FRL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

483547:GSUB RS11725
gene id: 483547:GSUB_RS11725
uniprot id: A0A0B5FIM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

483547:GSUB RS01250
gene id: 483547:GSUB_RS01250
uniprot id: A0A0B5FDV9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

483547:GSUB RS13790
gene id: 483547:GSUB_RS13790
uniprot id: A0A0B5FGY9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

483547:GSUB RS11030
gene id: 483547:GSUB_RS11030
uniprot id: A0A0B5FFT2
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS06985
gene id: 483547:GSUB_RS06985
uniprot id: A0A0B5FNV5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

483547:GSUB RS09570
gene id: 483547:GSUB_RS09570
uniprot id: A0A0B5FPZ4
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS08810
gene id: 483547:GSUB_RS08810
uniprot id: A0A0B5FES3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

483547:GSUB RS03890
gene id: 483547:GSUB_RS03890
uniprot id: A0A0B5FMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

483547:GSUB RS03720
gene id: 483547:GSUB_RS03720
uniprot id: A0A0B5FCE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS12070
gene id: 483547:GSUB_RS12070
uniprot id: A0A0B5FR88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

483547:GSUB RS11095
gene id: 483547:GSUB_RS11095
uniprot id: A0A0B5FFU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

483547:GSUB RS00690
gene id: 483547:GSUB_RS00690
uniprot id: A0A0B5FL63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

483547:GSUB RS11290
gene id: 483547:GSUB_RS11290
uniprot id: A0A0B5FI85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS01585
gene id: 483547:GSUB_RS01585
uniprot id: A0A0B5FUJ1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

483547:GSUB RS15435
gene id: 483547:GSUB_RS15435
uniprot id: A0A0B5FVQ4
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS00600
gene id: 483547:GSUB_RS00600
uniprot id: A0A0B5FP46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

483547:GSUB RS08250
gene id: 483547:GSUB_RS08250
uniprot id: A0A0B5FR26
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

483547:GSUB RS13230
gene id: 483547:GSUB_RS13230
uniprot id: A0A0B5FIZ0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

483547:GSUB RS19615
gene id: 483547:GSUB_RS19615
uniprot id: A0A0B5FRX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

483547:GSUB RS11715
gene id: 483547:GSUB_RS11715
uniprot id: A0A0B5FR32
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

483547:GSUB RS13890
gene id: 483547:GSUB_RS13890
uniprot id: A0A0B5FS03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

483547:GSUB RS12725
gene id: 483547:GSUB_RS12725
uniprot id: A0A0B5FIR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

483547:GSUB RS11680
gene id: 483547:GSUB_RS11680
uniprot id: A0A0B5FR27
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

483547:GSUB RS08275
gene id: 483547:GSUB_RS08275
uniprot id: A0A0B5FR28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

483547:GSUB RS10665
gene id: 483547:GSUB_RS10665
uniprot id: A0A0B5FQJ6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

483547:GSUB RS04545
gene id: 483547:GSUB_RS04545
uniprot id: A0A0B5FQV7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

483547:GSUB RS14565
gene id: 483547:GSUB_RS14565
uniprot id: A0A0B5FVC5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

483547:GSUB RS00025
gene id: 483547:GSUB_RS00025
uniprot id: A0A0B5FMU8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

483547:GSUB RS00760
gene id: 483547:GSUB_RS00760
uniprot id: A0A0B5FP80
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS08035
gene id: 483547:GSUB_RS08035
uniprot id: A0A0B5FQX1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

483547:GSUB RS07760
gene id: 483547:GSUB_RS07760
uniprot id: A0A0B5FQS2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

483547:GSUB RS12625
gene id: 483547:GSUB_RS12625
uniprot id: A0A0B5FRG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

483547:GSUB RS10610
gene id: 483547:GSUB_RS10610
uniprot id: A0A0B5FQI6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

483547:GSUB RS01630
gene id: 483547:GSUB_RS01630
uniprot id: A0A0B5FPP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

483547:GSUB RS08370
gene id: 483547:GSUB_RS08370
uniprot id: A0A0B5FR39
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS10980
gene id: 483547:GSUB_RS10980
uniprot id: A0A0B5FS61
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

483547:GSUB RS07165
gene id: 483547:GSUB_RS07165
uniprot id: A0A0B5FQJ5
names: Similarity
messages: Belongs to the GSP L family.

483547:GSUB RS14270
gene id: 483547:GSUB_RS14270
uniprot id: A0A0B5FL10
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

483547:GSUB RS16335
gene id: 483547:GSUB_RS16335
uniprot id: A0A0B5FHY5
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

483547:GSUB RS06810
gene id: 483547:GSUB_RS06810
uniprot id: A0A0B5FDS5
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

483547:GSUB RS02055
gene id: 483547:GSUB_RS02055
uniprot id: A0A0B5FBQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

483547:GSUB RS01460
gene id: 483547:GSUB_RS01460
uniprot id: A0A0B5FBG3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

483547:GSUB RS00595
gene id: 483547:GSUB_RS00595
uniprot id: A0A0B5FN11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

483547:GSUB RS06705
gene id: 483547:GSUB_RS06705
uniprot id: A0A0B5FNS4
names: Similarity
messages: Belongs to the histone deacetylase family.

483547:GSUB RS08270
gene id: 483547:GSUB_RS08270
uniprot id: A0A0B5FPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS10605
gene id: 483547:GSUB_RS10605
uniprot id: A0A0B5FHR3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

483547:GSUB RS14355
gene id: 483547:GSUB_RS14355
uniprot id: A0A0B5FV47
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

483547:GSUB RS07195
gene id: 483547:GSUB_RS07195
uniprot id: A0A0B5FQK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

483547:GSUB RS14795
gene id: 483547:GSUB_RS14795
uniprot id: A0A0B5FH99
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

483547:GSUB RS10435
gene id: 483547:GSUB_RS10435
uniprot id: A0A0B5FQF4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

483547:GSUB RS13035
gene id: 483547:GSUB_RS13035
uniprot id: A0A0B5FGL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

483547:GSUB RS08895
gene id: 483547:GSUB_RS08895
uniprot id: A0A0B5FH00
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

483547:GSUB RS00360
gene id: 483547:GSUB_RS00360
uniprot id: A0A0B5FNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS05755
gene id: 483547:GSUB_RS05755
uniprot id: A0A0B5FRG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS04205
gene id: 483547:GSUB_RS04205
uniprot id: A0A0B5FUN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

483547:GSUB RS14410
gene id: 483547:GSUB_RS14410
uniprot id: A0A0B5FTK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

483547:GSUB RS03655
gene id: 483547:GSUB_RS03655
uniprot id: A0A0B5FP37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS14080
gene id: 483547:GSUB_RS14080
uniprot id: A0A0B5FH25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

483547:GSUB RS15885
gene id: 483547:GSUB_RS15885
uniprot id: A0A0B5FSV7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

483547:GSUB RS09835
gene id: 483547:GSUB_RS09835
uniprot id: A0A0B5FT47
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

483547:GSUB RS05880
gene id: 483547:GSUB_RS05880
uniprot id: A0A0B5FFT0
names: Similarity
messages: Belongs to the P(II) protein family.

483547:GSUB RS05550
gene id: 483547:GSUB_RS05550
uniprot id: A0A0B5FDC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

483547:GSUB RS02100
gene id: 483547:GSUB_RS02100
uniprot id: A0A0B5FLU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

483547:GSUB RS08200
gene id: 483547:GSUB_RS08200
uniprot id: A0A0B5FSI0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

483547:GSUB RS02505
gene id: 483547:GSUB_RS02505
uniprot id: A0A0B5FED7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

483547:GSUB RS01800
gene id: 483547:GSUB_RS01800
uniprot id: A0A0B5FBN2
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS00705
gene id: 483547:GSUB_RS00705
uniprot id: A0A0B5FB60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

483547:GSUB RS16430
gene id: 483547:GSUB_RS16430
uniprot id: A0A0B5FW46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

483547:GSUB RS10520
gene id: 483547:GSUB_RS10520
uniprot id: A0A0B5FRX3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

483547:GSUB RS13815
gene id: 483547:GSUB_RS13815
uniprot id: A0A0B5FTC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

483547:GSUB RS07740
gene id: 483547:GSUB_RS07740
uniprot id: A0A0B5FS81
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS08970
gene id: 483547:GSUB_RS08970
uniprot id: A0A0B5FET7
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS15635
gene id: 483547:GSUB_RS15635
uniprot id: A0A0B5FU38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

483547:GSUB RS02530
gene id: 483547:GSUB_RS02530
uniprot id: A0A0B5FEE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

483547:GSUB RS05970
gene id: 483547:GSUB_RS05970
uniprot id: A0A0B5FRJ9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

483547:GSUB RS07710
gene id: 483547:GSUB_RS07710
uniprot id: A0A0B5FGL4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS07515
gene id: 483547:GSUB_RS07515
uniprot id: A0A0B5FS53
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

483547:GSUB RS05685
gene id: 483547:GSUB_RS05685
uniprot id: A0A0B5FFR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

483547:GSUB RS06495
gene id: 483547:GSUB_RS06495
uniprot id: A0A0B5FRS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

483547:GSUB RS07040
gene id: 483547:GSUB_RS07040
uniprot id: A0A0B5FDW2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

483547:GSUB RS11235
gene id: 483547:GSUB_RS11235
uniprot id: A0A0B5FI80
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

483547:GSUB RS06905
gene id: 483547:GSUB_RS06905
uniprot id: A0A0B5FRW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

483547:GSUB RS07175
gene id: 483547:GSUB_RS07175
uniprot id: A0A0B5FDY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

483547:GSUB RS07585
gene id: 483547:GSUB_RS07585
uniprot id: A0A0B5FS62
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

483547:GSUB RS14955
gene id: 483547:GSUB_RS14955
uniprot id: A0A0B5FHC0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

483547:GSUB RS07205
gene id: 483547:GSUB_RS07205
uniprot id: A0A0B5FDZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

483547:GSUB RS07995
gene id: 483547:GSUB_RS07995
uniprot id: A0A0B5FGR8
names: Similarity
messages: Belongs to the HepT RNase toxin family.

483547:GSUB RS00405
gene id: 483547:GSUB_RS00405
uniprot id: A0A0B5FL01
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS05255
gene id: 483547:GSUB_RS05255
uniprot id: A0A0B5FPW0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

483547:GSUB RS13000
gene id: 483547:GSUB_RS13000
uniprot id: A0A0B5FGL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

483547:GSUB RS14975
gene id: 483547:GSUB_RS14975
uniprot id: A0A0B5FVI5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

483547:GSUB RS13705
gene id: 483547:GSUB_RS13705
uniprot id: A0A0B5FTB2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

483547:GSUB RS03965
gene id: 483547:GSUB_RS03965
uniprot id: A0A0B5FQL4
names: Subcellular Location Annotation
messages: Mitochondrion

483547:GSUB RS10090
gene id: 483547:GSUB_RS10090
uniprot id: A0A0B5FRQ3
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CTCGAG-3' and cleaves after C-1.
messages: Belongs to the XhoI type II restriction endonuclease family.

483547:GSUB RS04200
gene id: 483547:GSUB_RS04200
uniprot id: A0A0B5FMP5
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS08410
gene id: 483547:GSUB_RS08410
uniprot id: A0A0B5FEN6
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS13695
gene id: 483547:GSUB_RS13695
uniprot id: A0A0B5FJ68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

483547:GSUB RS16535
gene id: 483547:GSUB_RS16535
uniprot id: A0A0B5FIU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

483547:GSUB RS11735
gene id: 483547:GSUB_RS11735
uniprot id: A0A0B5FG46
names: Similarity
messages: Belongs to the UPF0235 family.

483547:GSUB RS04840
gene id: 483547:GSUB_RS04840
uniprot id: A0A0B5FPP8
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

483547:GSUB RS07725
gene id: 483547:GSUB_RS07725
uniprot id: A0A0B5FQR8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

483547:GSUB RS00420
gene id: 483547:GSUB_RS00420
uniprot id: A0A0B5FB11
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

483547:GSUB RS11705
gene id: 483547:GSUB_RS11705
uniprot id: A0A0B5FID1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

483547:GSUB RS12630
gene id: 483547:GSUB_RS12630
uniprot id: A0A0B5FSV1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

483547:GSUB RS07690
gene id: 483547:GSUB_RS07690
uniprot id: A0A0B5FP78
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

483547:GSUB RS12535
gene id: 483547:GSUB_RS12535
uniprot id: A0A0B5FGF3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

483547:GSUB RS11060
gene id: 483547:GSUB_RS11060
uniprot id: A0A0B5FFT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

483547:GSUB RS02535
gene id: 483547:GSUB_RS02535
uniprot id: A0A0B5FM09
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

483547:GSUB RS08710
gene id: 483547:GSUB_RS08710
uniprot id: A0A0B5FER3
names: Similarity
messages: Belongs to the UPF0270 family.

483547:GSUB RS00735
gene id: 483547:GSUB_RS00735
uniprot id: A0A0B5FDM5
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS10900
gene id: 483547:GSUB_RS10900
uniprot id: A0A0B5FQP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

483547:GSUB RS07780
gene id: 483547:GSUB_RS07780
uniprot id: A0A0B5FP89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

483547:GSUB RS07200
gene id: 483547:GSUB_RS07200
uniprot id: A0A0B5FS12
names: Similarity
messages: Belongs to the GSP E family.

483547:GSUB RS00410
gene id: 483547:GSUB_RS00410
uniprot id: A0A0B5FMY7
names: Similarity
messages: Belongs to the universal stress protein A family.

483547:GSUB RS09665
gene id: 483547:GSUB_RS09665
uniprot id: A0A0B5FT19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

483547:GSUB RS13840
gene id: 483547:GSUB_RS13840
uniprot id: A0A0B5FJ88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

483547:GSUB RS14845
gene id: 483547:GSUB_RS14845
uniprot id: A0A0B5FTR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

483547:GSUB RS10460
gene id: 483547:GSUB_RS10460
uniprot id: A0A0B5FQG1
names: Similarity
messages: Belongs to the Skp family.

483547:GSUB RS01480
gene id: 483547:GSUB_RS01480
uniprot id: A0A0B5FPJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

483547:GSUB RS01995
gene id: 483547:GSUB_RS01995
uniprot id: A0A0B5FE82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

483547:GSUB RS07810
gene id: 483547:GSUB_RS07810
uniprot id: A0A0B5FQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS15815
gene id: 483547:GSUB_RS15815
uniprot id: A0A0B5FHR0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

483547:GSUB RS15845
gene id: 483547:GSUB_RS15845
uniprot id: A0A0B5FHR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

483547:GSUB RS13265
gene id: 483547:GSUB_RS13265
uniprot id: A0A0B5FT50
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

483547:GSUB RS14465
gene id: 483547:GSUB_RS14465
uniprot id: A0A0B5FS78
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

483547:GSUB RS16705
gene id: 483547:GSUB_RS16705
uniprot id: A0A0B5FVD8
names: Similarity
messages: Belongs to the ros/MucR family.

483547:GSUB RS09270
gene id: 483547:GSUB_RS09270
uniprot id: A0A0B5FRD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

483547:GSUB RS02780
gene id: 483547:GSUB_RS02780
uniprot id: A0A0B5FQ37
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

483547:GSUB RS10285
gene id: 483547:GSUB_RS10285
uniprot id: A0A0B5FRT5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

483547:GSUB RS16510
gene id: 483547:GSUB_RS16510
uniprot id: A0A0B5FL47
names: Similarity
messages: Belongs to the bacterial secretin family.

483547:GSUB RS00675
gene id: 483547:GSUB_RS00675
uniprot id: A0A0B5FP68
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

483547:GSUB RS03260
gene id: 483547:GSUB_RS03260
uniprot id: A0A0B5FC80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

483547:GSUB RS04775
gene id: 483547:GSUB_RS04775
uniprot id: A0A0B5FN07
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

483547:GSUB RS09170
gene id: 483547:GSUB_RS09170
uniprot id: A0A0B5FH31
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

483547:GSUB RS07655
gene id: 483547:GSUB_RS07655
uniprot id: A0A0B5FE53
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

483547:GSUB RS12540
gene id: 483547:GSUB_RS12540
uniprot id: A0A0B5FIM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

483547:GSUB RS14940
gene id: 483547:GSUB_RS14940
uniprot id: A0A0B5FVH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

483547:GSUB RS07765
gene id: 483547:GSUB_RS07765
uniprot id: A0A0B5FS85
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

483547:GSUB RS03850
gene id: 483547:GSUB_RS03850
uniprot id: A0A0B5FCG2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

483547:GSUB RS04245
gene id: 483547:GSUB_RS04245
uniprot id: A0A0B5FMQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

483547:GSUB RS06105
gene id: 483547:GSUB_RS06105
uniprot id: A0A0B5FQ51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

483547:GSUB RS11090
gene id: 483547:GSUB_RS11090
uniprot id: A0A0B5FTN3
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

483547:GSUB RS00295
gene id: 483547:GSUB_RS00295
uniprot id: A0A0B5FAY7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

483547:GSUB RS10075
gene id: 483547:GSUB_RS10075
uniprot id: A0A0B5FQ87
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

483547:GSUB RS03680
gene id: 483547:GSUB_RS03680
uniprot id: A0A0B5FMG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

483547:GSUB RS00010
gene id: 483547:GSUB_RS00010
uniprot id: A0A0B5FDB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

483547:GSUB RS15055
gene id: 483547:GSUB_RS15055
uniprot id: A0A0B5FSH6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

483547:GSUB RS14620
gene id: 483547:GSUB_RS14620
uniprot id: A0A0B5FVD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

483547:GSUB RS05205
gene id: 483547:GSUB_RS05205
uniprot id: A0A0B5FD72
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

483547:GSUB RS02710
gene id: 483547:GSUB_RS02710
uniprot id: A0A0B5FEG1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

483547:GSUB RS04180
gene id: 483547:GSUB_RS04180
uniprot id: A0A0B5FQQ2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

483547:GSUB RS14125
gene id: 483547:GSUB_RS14125
uniprot id: A0A0B5FTG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

483547:GSUB RS05540
gene id: 483547:GSUB_RS05540
uniprot id: A0A0B5FRE4
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

483547:GSUB RS12805
gene id: 483547:GSUB_RS12805
uniprot id: A0A0B5FRJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

483547:GSUB RS01205
gene id: 483547:GSUB_RS01205
uniprot id: A0A0B5FDV4
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS03040
gene id: 483547:GSUB_RS03040
uniprot id: A0A0B5FNX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

483547:GSUB RS05830
gene id: 483547:GSUB_RS05830
uniprot id: A0A0B5FRH7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

483547:GSUB RS00160
gene id: 483547:GSUB_RS00160
uniprot id: A0A0B5FAX0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

483547:GSUB RS14160
gene id: 483547:GSUB_RS14160
uniprot id: A0A0B5FTG6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

483547:GSUB RS12370
gene id: 483547:GSUB_RS12370
uniprot id: A0A0B5FGD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

483547:GSUB RS04515
gene id: 483547:GSUB_RS04515
uniprot id: A0A0B5FCS0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS15595
gene id: 483547:GSUB_RS15595
uniprot id: A0A0B5FJX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

483547:GSUB RS01745
gene id: 483547:GSUB_RS01745
uniprot id: A0A0B5FNI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS09515
gene id: 483547:GSUB_RS09515
uniprot id: A0A0B5FPY1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

483547:GSUB RS13595
gene id: 483547:GSUB_RS13595
uniprot id: A0A0B5FUU6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS03270
gene id: 483547:GSUB_RS03270
uniprot id: A0A0B5FMA9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

483547:GSUB RS05245
gene id: 483547:GSUB_RS05245
uniprot id: A0A0B5FFM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

483547:GSUB RS12350
gene id: 483547:GSUB_RS12350
uniprot id: A0A0B5FIL2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

483547:GSUB RS03585
gene id: 483547:GSUB_RS03585
uniprot id: A0A0B5FET0
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

483547:GSUB RS06465
gene id: 483547:GSUB_RS06465
uniprot id: A0A0B5FDN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

483547:GSUB RS00375
gene id: 483547:GSUB_RS00375
uniprot id: A0A0B5FKZ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

483547:GSUB RS15530
gene id: 483547:GSUB_RS15530
uniprot id: A0A0B5FJX2
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS02355
gene id: 483547:GSUB_RS02355
uniprot id: A0A0B5FBU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS14850
gene id: 483547:GSUB_RS14850
uniprot id: A0A0B5FVG6
names: Similarity
messages: Belongs to the bacterial flagellin family.

483547:GSUB RS13300
gene id: 483547:GSUB_RS13300
uniprot id: A0A0B5FRR3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

483547:GSUB RS03000
gene id: 483547:GSUB_RS03000
uniprot id: A0A0B5FM70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

483547:GSUB RS04210
gene id: 483547:GSUB_RS04210
uniprot id: A0A0B5FPA4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

483547:GSUB RS09250
gene id: 483547:GSUB_RS09250
uniprot id: A0A0B5FSV8
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

483547:GSUB RS11160
gene id: 483547:GSUB_RS11160
uniprot id: A0A0B5FS86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS09050
gene id: 483547:GSUB_RS09050
uniprot id: A0A0B5FEU5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

483547:GSUB RS13330
gene id: 483547:GSUB_RS13330
uniprot id: A0A0B5FJ11
names: Similarity
messages: Belongs to the SfsA family.

483547:GSUB RS12750
gene id: 483547:GSUB_RS12750
uniprot id: A0A0B5FRI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

483547:GSUB RS00390
gene id: 483547:GSUB_RS00390
uniprot id: A0A0B5FNZ9
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS02510
gene id: 483547:GSUB_RS02510
uniprot id: A0A0B5FM02
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

483547:GSUB RS05290
gene id: 483547:GSUB_RS05290
uniprot id: A0A0B5FRB0
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS12560
gene id: 483547:GSUB_RS12560
uniprot id: A0A0B5FGF8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

483547:GSUB RS08020
gene id: 483547:GSUB_RS08020
uniprot id: A0A0B5FEC9
names: Similarity
messages: Belongs to the HepT RNase toxin family.

483547:GSUB RS02460
gene id: 483547:GSUB_RS02460
uniprot id: A0A0B5FLZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

483547:GSUB RS02765
gene id: 483547:GSUB_RS02765
uniprot id: A0A0B5FEG9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

483547:GSUB RS03005
gene id: 483547:GSUB_RS03005
uniprot id: A0A0B5FNW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

483547:GSUB RS11935
gene id: 483547:GSUB_RS11935
uniprot id: A0A0B5FG78
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

483547:GSUB RS17450
gene id: 483547:GSUB_RS17450
uniprot id: A0A0B5FLF9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

483547:GSUB RS00335
gene id: 483547:GSUB_RS00335
uniprot id: A0A0B5FNY8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

483547:GSUB RS08390
gene id: 483547:GSUB_RS08390
uniprot id: A0A0B5FPJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS06860
gene id: 483547:GSUB_RS06860
uniprot id: A0A0B5FNT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

483547:GSUB RS06965
gene id: 483547:GSUB_RS06965
uniprot id: A0A0B5FQG0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

483547:GSUB RS00365
gene id: 483547:GSUB_RS00365
uniprot id: A0A0B5FAZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS00640
gene id: 483547:GSUB_RS00640
uniprot id: A0A0B5FL51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

483547:GSUB RS00720
gene id: 483547:GSUB_RS00720
uniprot id: A0A0B5FN35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

483547:GSUB RS01400
gene id: 483547:GSUB_RS01400
uniprot id: A0A0B5FBF0
names: Similarity
messages: Belongs to the CobH/CbiC family.

483547:GSUB RS11750
gene id: 483547:GSUB_RS11750
uniprot id: A0A0B5FSH7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

483547:GSUB RS02325
gene id: 483547:GSUB_RS02325
uniprot id: A0A0B5FBT6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

483547:GSUB RS02340
gene id: 483547:GSUB_RS02340
uniprot id: A0A0B5FLW9
names: Similarity
messages: Belongs to the ALAD family.

483547:GSUB RS01610
gene id: 483547:GSUB_RS01610
uniprot id: A0A0B5FE44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

483547:GSUB RS09280
gene id: 483547:GSUB_RS09280
uniprot id: A0A0B5FEX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

483547:GSUB RS05645
gene id: 483547:GSUB_RS05645
uniprot id: A0A0B5FDD5
names: Similarity
messages: Belongs to the citrate synthase family.

483547:GSUB RS03045
gene id: 483547:GSUB_RS03045
uniprot id: A0A0B5FQ81
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

483547:GSUB RS09860
gene id: 483547:GSUB_RS09860
uniprot id: A0A0B5FRL8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

483547:GSUB RS10800
gene id: 483547:GSUB_RS10800
uniprot id: A0A0B5FFM4
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

483547:GSUB RS13345
gene id: 483547:GSUB_RS13345
uniprot id: A0A0B5FUQ1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

483547:GSUB RS12690
gene id: 483547:GSUB_RS12690
uniprot id: A0A0B5FGI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

483547:GSUB RS01295
gene id: 483547:GSUB_RS01295
uniprot id: A0A0B5FDW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

483547:GSUB RS01090
gene id: 483547:GSUB_RS01090
uniprot id: A0A0B5FBB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

483547:GSUB RS11940
gene id: 483547:GSUB_RS11940
uniprot id: A0A0B5FIG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

483547:GSUB RS14890
gene id: 483547:GSUB_RS14890
uniprot id: A0A0B5FJP8
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

483547:GSUB RS06900
gene id: 483547:GSUB_RS06900
uniprot id: A0A0B5FQF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

483547:GSUB RS11125
gene id: 483547:GSUB_RS11125
uniprot id: A0A0B5FI15
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

483547:GSUB RS10830
gene id: 483547:GSUB_RS10830
uniprot id: A0A0B5FFM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

483547:GSUB RS10525
gene id: 483547:GSUB_RS10525
uniprot id: A0A0B5FTE8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

483547:GSUB RS13630
gene id: 483547:GSUB_RS13630
uniprot id: A0A0B5FGV0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

483547:GSUB RS11455
gene id: 483547:GSUB_RS11455
uniprot id: A0A0B5FR03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS14400
gene id: 483547:GSUB_RS14400
uniprot id: A0A0B5FJF8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

483547:GSUB RS09295
gene id: 483547:GSUB_RS09295
uniprot id: A0A0B5FPV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

483547:GSUB RS14000
gene id: 483547:GSUB_RS14000
uniprot id: A0A0B5FH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

483547:GSUB RS13835
gene id: 483547:GSUB_RS13835
uniprot id: A0A0B5FGZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

483547:GSUB RS04880
gene id: 483547:GSUB_RS04880
uniprot id: A0A0B5FD13
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

483547:GSUB RS05070
gene id: 483547:GSUB_RS05070
uniprot id: A0A0B5FFK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

483547:GSUB RS13220
gene id: 483547:GSUB_RS13220
uniprot id: A0A0B5FUN5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

483547:GSUB RS02305
gene id: 483547:GSUB_RS02305
uniprot id: A0A0B5FLW6
names: Similarity
messages: Belongs to the thioredoxin family.

483547:GSUB RS02465
gene id: 483547:GSUB_RS02465
uniprot id: A0A0B5FNQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

483547:GSUB RS12375
gene id: 483547:GSUB_RS12375
uniprot id: A0A0B5FIL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

483547:GSUB RS08695
gene id: 483547:GSUB_RS08695
uniprot id: A0A0B5FR67
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

483547:GSUB RS06120
gene id: 483547:GSUB_RS06120
uniprot id: A0A0B5FFV8
names: Similarity
messages: Belongs to the peptidase S41A family.

483547:GSUB RS10960
gene id: 483547:GSUB_RS10960
uniprot id: A0A0B5FTL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

483547:GSUB RS12915
gene id: 483547:GSUB_RS12915
uniprot id: A0A0B5FSZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

483547:GSUB RS02575
gene id: 483547:GSUB_RS02575
uniprot id: A0A0B5FPZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

483547:GSUB RS10890
gene id: 483547:GSUB_RS10890
uniprot id: A0A0B5FFN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS12450
gene id: 483547:GSUB_RS12450
uniprot id: A0A0B5FUC5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

483547:GSUB RS13805
gene id: 483547:GSUB_RS13805
uniprot id: A0A0B5FJ82
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

483547:GSUB RS09290
gene id: 483547:GSUB_RS09290
uniprot id: A0A0B5FIH0
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

483547:GSUB RS06875
gene id: 483547:GSUB_RS06875
uniprot id: A0A0B5FQE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

483547:GSUB RS00195
gene id: 483547:GSUB_RS00195
uniprot id: A0A0B5FMW2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

483547:GSUB RS00005
gene id: 483547:GSUB_RS00005
uniprot id: A0A0B5FAV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

483547:GSUB RS13095
gene id: 483547:GSUB_RS13095
uniprot id: A0A0B5FRN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

483547:GSUB RS00800
gene id: 483547:GSUB_RS00800
uniprot id: A0A0B5FB75
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

483547:GSUB RS09080
gene id: 483547:GSUB_RS09080
uniprot id: A0A0B5FST6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

483547:GSUB RS05210
gene id: 483547:GSUB_RS05210
uniprot id: A0A0B5FFM2
names: Similarity
messages: Belongs to the CvfB family.

483547:GSUB RS00605
gene id: 483547:GSUB_RS00605
uniprot id: A0A0B5FB44
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS11260
gene id: 483547:GSUB_RS11260
uniprot id: A0A0B5FFY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

483547:GSUB RS11325
gene id: 483547:GSUB_RS11325
uniprot id: A0A0B5FQZ6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

483547:GSUB RS03235
gene id: 483547:GSUB_RS03235
uniprot id: A0A0B5FEN7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS03280
gene id: 483547:GSUB_RS03280
uniprot id: A0A0B5FQB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

483547:GSUB RS10705
gene id: 483547:GSUB_RS10705
uniprot id: A0A0B5FS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS02680
gene id: 483547:GSUB_RS02680
uniprot id: A0A0B5FKE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

483547:GSUB RS04440
gene id: 483547:GSUB_RS04440
uniprot id: A0A0B5FQU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

483547:GSUB RS12700
gene id: 483547:GSUB_RS12700
uniprot id: A0A0B5FRH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

483547:GSUB RS04810
gene id: 483547:GSUB_RS04810
uniprot id: A0A0B5FN15
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

483547:GSUB RS09625
gene id: 483547:GSUB_RS09625
uniprot id: A0A0B5FQ06
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS14405
gene id: 483547:GSUB_RS14405
uniprot id: A0A0B5FS67
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

483547:GSUB RS05000
gene id: 483547:GSUB_RS05000
uniprot id: A0A0B5FD38
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

483547:GSUB RS09375
gene id: 483547:GSUB_RS09375
uniprot id: A0A0B5FRE5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

483547:GSUB RS03200
gene id: 483547:GSUB_RS03200
uniprot id: A0A0B5FT94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

483547:GSUB RS12225
gene id: 483547:GSUB_RS12225
uniprot id: A0A0B5FRA2
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

483547:GSUB RS05840
gene id: 483547:GSUB_RS05840
uniprot id: A0A0B5FFS7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

483547:GSUB RS08785
gene id: 483547:GSUB_RS08785
uniprot id: A0A0B5FES0
names: Similarity
messages: Belongs to the TPP enzyme family.

483547:GSUB RS02565
gene id: 483547:GSUB_RS02565
uniprot id: A0A0B5FNR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

483547:GSUB RS05580
gene id: 483547:GSUB_RS05580
uniprot id: A0A0B5FPZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

483547:GSUB RS07025
gene id: 483547:GSUB_RS07025
uniprot id: A0A0B5FNW1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

483547:GSUB RS01865
gene id: 483547:GSUB_RS01865
uniprot id: A0A0B5FLR4
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS15760
gene id: 483547:GSUB_RS15760
uniprot id: A0A0B5FHP9
names: Similarity
messages: Belongs to the UPF0758 family.

483547:GSUB RS03400
gene id: 483547:GSUB_RS03400
uniprot id: A0A0B5FMC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

483547:GSUB RS16750
gene id: 483547:GSUB_RS16750
uniprot id: A0A0B5FX24
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

483547:GSUB RS09460
gene id: 483547:GSUB_RS09460
uniprot id: A0A0B5FRF8
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS06845
gene id: 483547:GSUB_RS06845
uniprot id: A0A0B5FDT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS13715
gene id: 483547:GSUB_RS13715
uniprot id: A0A0B5FGX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

483547:GSUB RS10455
gene id: 483547:GSUB_RS10455
uniprot id: A0A0B5FHP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

483547:GSUB RS03520
gene id: 483547:GSUB_RS03520
uniprot id: A0A0B5FME1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

483547:GSUB RS12790
gene id: 483547:GSUB_RS12790
uniprot id: A0A0B5FUH7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

483547:GSUB RS07255
gene id: 483547:GSUB_RS07255
uniprot id: A0A0B5FNZ7
names: Similarity
messages: Belongs to the MlaA family.

483547:GSUB RS07835
gene id: 483547:GSUB_RS07835
uniprot id: A0A0B5FWH5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

483547:GSUB RS12965
gene id: 483547:GSUB_RS12965
uniprot id: A0A0B5FUJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

483547:GSUB RS13895
gene id: 483547:GSUB_RS13895
uniprot id: A0A0B5FTD7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

483547:GSUB RS02125
gene id: 483547:GSUB_RS02125
uniprot id: A0A0B5FBR5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

483547:GSUB RS01245
gene id: 483547:GSUB_RS01245
uniprot id: A0A0B5FBD1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

483547:GSUB RS09580
gene id: 483547:GSUB_RS09580
uniprot id: A0A0B5FT07
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

483547:GSUB RS03170
gene id: 483547:GSUB_RS03170
uniprot id: A0A0B5FM93
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

483547:GSUB RS01430
gene id: 483547:GSUB_RS01430
uniprot id: A0A0B5FBF6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

483547:GSUB RS04665
gene id: 483547:GSUB_RS04665
uniprot id: A0A0B5FFA8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

483547:GSUB RS12485
gene id: 483547:GSUB_RS12485
uniprot id: A0A0B5FIM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

483547:GSUB RS03895
gene id: 483547:GSUB_RS03895
uniprot id: A0A0B5FP60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

483547:GSUB RS13505
gene id: 483547:GSUB_RS13505
uniprot id: A0A0B5FT81
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

483547:GSUB RS00740
gene id: 483547:GSUB_RS00740
uniprot id: A0A0B5FL74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

483547:GSUB RS12475
gene id: 483547:GSUB_RS12475
uniprot id: A0A0B5FUC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

483547:GSUB RS11495
gene id: 483547:GSUB_RS11495
uniprot id: A0A0B5FTZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

483547:GSUB RS02155
gene id: 483547:GSUB_RS02155
uniprot id: A0A0B5FE98
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

483547:GSUB RS14725
gene id: 483547:GSUB_RS14725
uniprot id: A0A0B5FSD6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

483547:GSUB RS12315
gene id: 483547:GSUB_RS12315
uniprot id: A0A0B5FGB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

483547:GSUB RS15580
gene id: 483547:GSUB_RS15580
uniprot id: A0A0B5FU29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

483547:GSUB RS01940
gene id: 483547:GSUB_RS01940
uniprot id: A0A0B5FBP6
names: Similarity
messages: Belongs to the glutamate synthase family.

483547:GSUB RS13850
gene id: 483547:GSUB_RS13850
uniprot id: A0A0B5FRZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

483547:GSUB RS14915
gene id: 483547:GSUB_RS14915
uniprot id: A0A0B5FJQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

483547:GSUB RS15710
gene id: 483547:GSUB_RS15710
uniprot id: A0A0B5FHP0
names: Similarity
messages: Belongs to the universal stress protein A family.

483547:GSUB RS06570
gene id: 483547:GSUB_RS06570
uniprot id: A0A0B5FUM9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

483547:GSUB RS08945
gene id: 483547:GSUB_RS08945
uniprot id: A0A0B5FPQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

483547:GSUB RS07350
gene id: 483547:GSUB_RS07350
uniprot id: A0A0B5FGF2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

483547:GSUB RS10325
gene id: 483547:GSUB_RS10325
uniprot id: A0A0B5FTJ3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

483547:GSUB RS11710
gene id: 483547:GSUB_RS11710
uniprot id: A0A0B5FWQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

483547:GSUB RS14835
gene id: 483547:GSUB_RS14835
uniprot id: A0A0B5FJP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

483547:GSUB RS02035
gene id: 483547:GSUB_RS02035
uniprot id: A0A0B5FUK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

483547:GSUB RS12570
gene id: 483547:GSUB_RS12570
uniprot id: A0A0B5FRF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

483547:GSUB RS05640
gene id: 483547:GSUB_RS05640
uniprot id: A0A0B5FRF7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

483547:GSUB RS04450
gene id: 483547:GSUB_RS04450
uniprot id: A0A0B5FCQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

483547:GSUB RS02490
gene id: 483547:GSUB_RS02490
uniprot id: A0A0B5FNQ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS07535
gene id: 483547:GSUB_RS07535
uniprot id: A0A0B5FP40
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

483547:GSUB RS07850
gene id: 483547:GSUB_RS07850
uniprot id: A0A0B5FQU0
names: Similarity
messages: Belongs to the heat shock protein 90 family.

483547:GSUB RS12390
gene id: 483547:GSUB_RS12390
uniprot id: A0A0B5FRC4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

483547:GSUB RS09145
gene id: 483547:GSUB_RS09145
uniprot id: A0A0B5FH27
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

483547:GSUB RS11200
gene id: 483547:GSUB_RS11200
uniprot id: A0A0B5FFY1
names: Similarity
messages: Belongs to the ros/MucR family.

483547:GSUB RS12705
gene id: 483547:GSUB_RS12705
uniprot id: A0A0B5FSW7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

483547:GSUB RS14650
gene id: 483547:GSUB_RS14650
uniprot id: A0A0B5FSC5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

483547:GSUB RS05955
gene id: 483547:GSUB_RS05955
uniprot id: A0A0B5FFU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

483547:GSUB RS08885
gene id: 483547:GSUB_RS08885
uniprot id: A0A0B5FSR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

483547:GSUB RS06065
gene id: 483547:GSUB_RS06065
uniprot id: A0A0B5FQ46
names: Similarity
messages: Belongs to the GSP E family.

483547:GSUB RS15825
gene id: 483547:GSUB_RS15825
uniprot id: A0A0B5FSU7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

483547:GSUB RS12585
gene id: 483547:GSUB_RS12585
uniprot id: A0A0B5FGG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

483547:GSUB RS01760
gene id: 483547:GSUB_RS01760
uniprot id: A0A0B5FPQ2
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS17400
gene id: 483547:GSUB_RS17400
uniprot id: A0A0B5FJA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

483547:GSUB RS05965
gene id: 483547:GSUB_RS05965
uniprot id: A0A0B5FQ36
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

483547:GSUB RS12130
gene id: 483547:GSUB_RS12130
uniprot id: A0A0B5FSN7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

483547:GSUB RS00435
gene id: 483547:GSUB_RS00435
uniprot id: A0A0B5FMZ2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

483547:GSUB RS13335
gene id: 483547:GSUB_RS13335
uniprot id: A0A0B5FRR6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

483547:GSUB RS07595
gene id: 483547:GSUB_RS07595
uniprot id: A0A0B5FGI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

483547:GSUB RS00660
gene id: 483547:GSUB_RS00660
uniprot id: A0A0B5FDK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

483547:GSUB RS03180
gene id: 483547:GSUB_RS03180
uniprot id: A0A0B5FQA0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

483547:GSUB RS12470
gene id: 483547:GSUB_RS12470
uniprot id: A0A0B5FSS5
names: Similarity
messages: Belongs to the DEAD box helicase family.

483547:GSUB RS09195
gene id: 483547:GSUB_RS09195
uniprot id: A0A0B5FH36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

483547:GSUB RS15625
gene id: 483547:GSUB_RS15625
uniprot id: A0A0B5FJY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS13615
gene id: 483547:GSUB_RS13615
uniprot id: A0A0B5FT96
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

483547:GSUB RS14390
gene id: 483547:GSUB_RS14390
uniprot id: A0A0B5FV53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

483547:GSUB RS12580
gene id: 483547:GSUB_RS12580
uniprot id: A0A0B5FUE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

483547:GSUB RS11065
gene id: 483547:GSUB_RS11065
uniprot id: A0A0B5FI02
names: Similarity
messages: Belongs to the sigma-54 factor family.

483547:GSUB RS05600
gene id: 483547:GSUB_RS05600
uniprot id: A0A0B5FFQ4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

483547:GSUB RS11745
gene id: 483547:GSUB_RS11745
uniprot id: A0A0B5FR36
names: Similarity
messages: Belongs to the YggT family.

483547:GSUB RS03305
gene id: 483547:GSUB_RS03305
uniprot id: A0A0B5FEP8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

483547:GSUB RS13050
gene id: 483547:GSUB_RS13050
uniprot id: A0A0B5FT18
names: Similarity
messages: Belongs to the acylphosphatase family.

483547:GSUB RS14895
gene id: 483547:GSUB_RS14895
uniprot id: A0A0B5FSF6
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

483547:GSUB RS15835
gene id: 483547:GSUB_RS15835
uniprot id: A0A0B5FVX0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS14015
gene id: 483547:GSUB_RS14015
uniprot id: A0A0B5FJB0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

483547:GSUB RS01910
gene id: 483547:GSUB_RS01910
uniprot id: A0A0B5FNK4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

483547:GSUB RS04505
gene id: 483547:GSUB_RS04505
uniprot id: A0A0B5FQV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

483547:GSUB RS04475
gene id: 483547:GSUB_RS04475
uniprot id: A0A0B5FQU6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

483547:GSUB RS09365
gene id: 483547:GSUB_RS09365
uniprot id: A0A0B5FH55
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

483547:GSUB RS03060
gene id: 483547:GSUB_RS03060
uniprot id: A0A0B5FM79
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

483547:GSUB RS01880
gene id: 483547:GSUB_RS01880
uniprot id: A0A0B5FPR4
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS04565
gene id: 483547:GSUB_RS04565
uniprot id: A0A0B5FMW7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

483547:GSUB RS01795
gene id: 483547:GSUB_RS01795
uniprot id: A0A0B5FPQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Membrane

483547:GSUB RS14695
gene id: 483547:GSUB_RS14695
uniprot id: A0A0B5FJM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

483547:GSUB RS13085
gene id: 483547:GSUB_RS13085
uniprot id: A0A0B5FGM3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

483547:GSUB RS12460
gene id: 483547:GSUB_RS12460
uniprot id: A0A0B5FIL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

483547:GSUB RS10945
gene id: 483547:GSUB_RS10945
uniprot id: A0A0B5FHX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

483547:GSUB RS13045
gene id: 483547:GSUB_RS13045
uniprot id: A0A0B5FRM6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

483547:GSUB RS06340
gene id: 483547:GSUB_RS06340
uniprot id: A0A0B5FNM9
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS09245
gene id: 483547:GSUB_RS09245
uniprot id: A0A0B5FRD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

483547:GSUB RS00080
gene id: 483547:GSUB_RS00080
uniprot id: A0A0B5FAW0
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

483547:GSUB RS11795
gene id: 483547:GSUB_RS11795
uniprot id: A0A0B5FIE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS16850
gene id: 483547:GSUB_RS16850
uniprot id: A0A0B5FVG8
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

483547:GSUB RS10630
gene id: 483547:GSUB_RS10630
uniprot id: A0A0B5FHS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

483547:GSUB RS00710
gene id: 483547:GSUB_RS00710
uniprot id: A0A0B5FDM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

483547:GSUB RS13030
gene id: 483547:GSUB_RS13030
uniprot id: A0A0B5FUK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

483547:GSUB RS02445
gene id: 483547:GSUB_RS02445
uniprot id: A0A0B5FBV1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

483547:GSUB RS14155
gene id: 483547:GSUB_RS14155
uniprot id: A0A0B5FS36
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

483547:GSUB RS13105
gene id: 483547:GSUB_RS13105
uniprot id: A0A0B5FUL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

483547:GSUB RS15590
gene id: 483547:GSUB_RS15590
uniprot id: A0A0B5FHM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

483547:GSUB RS04800
gene id: 483547:GSUB_RS04800
uniprot id: A0A0B5FFD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS09560
gene id: 483547:GSUB_RS09560
uniprot id: A0A0B5FF10
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

483547:GSUB RS03430
gene id: 483547:GSUB_RS03430
uniprot id: A0A0B5FER1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

483547:GSUB RS14855
gene id: 483547:GSUB_RS14855
uniprot id: A0A0B5FHA6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

483547:GSUB RS15585
gene id: 483547:GSUB_RS15585
uniprot id: A0A0B5FVS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

483547:GSUB RS04865
gene id: 483547:GSUB_RS04865
uniprot id: A0A0B5FPQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

483547:GSUB RS10330
gene id: 483547:GSUB_RS10330
uniprot id: A0A0B5FHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

483547:GSUB RS07620
gene id: 483547:GSUB_RS07620
uniprot id: A0A0B5FGJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

483547:GSUB RS00275
gene id: 483547:GSUB_RS00275
uniprot id: A0A0B5FDE8
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS00385
gene id: 483547:GSUB_RS00385
uniprot id: A0A0B5FMY3
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS16400
gene id: 483547:GSUB_RS16400
uniprot id: A0A0B5FW43
names: Similarity
messages: Belongs to the ParB family.

483547:GSUB RS03095
gene id: 483547:GSUB_RS03095
uniprot id: A0A0B5FM83
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

483547:GSUB RS13075
gene id: 483547:GSUB_RS13075
uniprot id: A0A0B5FT21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

483547:GSUB RS13585
gene id: 483547:GSUB_RS13585
uniprot id: A0A0B5FRV4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

483547:GSUB RS09305
gene id: 483547:GSUB_RS09305
uniprot id: A0A0B5FRD8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

483547:GSUB RS06160
gene id: 483547:GSUB_RS06160
uniprot id: A0A0B5FFW4
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

483547:GSUB RS06165
gene id: 483547:GSUB_RS06165
uniprot id: A0A0B5FNK3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

483547:GSUB RS10990
gene id: 483547:GSUB_RS10990
uniprot id: A0A0B5FTM1
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS03455
gene id: 483547:GSUB_RS03455
uniprot id: A0A0B5FP18
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

483547:GSUB RS05975
gene id: 483547:GSUB_RS05975
uniprot id: A0A0B5FUR9
names: Subcellular Location Annotation
messages: Cytoplasm

483547:GSUB RS06990
gene id: 483547:GSUB_RS06990
uniprot id: A0A0B5FQG5
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

483547:GSUB RS07750
gene id: 483547:GSUB_RS07750
uniprot id: A0A0B5FGM2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

483547:GSUB RS09370
gene id: 483547:GSUB_RS09370
uniprot id: A0A0B5FPW1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS11385
gene id: 483547:GSUB_RS11385
uniprot id: A0A0B5FTX7
names: Similarity
messages: Belongs to the group II decarboxylase family.

483547:GSUB RS05885
gene id: 483547:GSUB_RS05885
uniprot id: A0A0B5FNH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

483547:GSUB RS12505
gene id: 483547:GSUB_RS12505
uniprot id: A0A0B5FGE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

483547:GSUB RS12675
gene id: 483547:GSUB_RS12675
uniprot id: A0A0B5FRH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

483547:GSUB RS13210
gene id: 483547:GSUB_RS13210
uniprot id: A0A0B5FRQ1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

483547:GSUB RS12665
gene id: 483547:GSUB_RS12665
uniprot id: A0A0B5FGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

483547:GSUB RS03160
gene id: 483547:GSUB_RS03160
uniprot id: A0A0B5FC64
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

483547:GSUB RS04490
gene id: 483547:GSUB_RS04490
uniprot id: A0A0B5FF86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

483547:GSUB RS15600
gene id: 483547:GSUB_RS15600
uniprot id: A0A0B5FSQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

483547:GSUB RS15485
gene id: 483547:GSUB_RS15485
uniprot id: A0A0B5FU12
names: Similarity
messages: Belongs to the phosphohexose mutase family.

483547:GSUB RS15715
gene id: 483547:GSUB_RS15715
uniprot id: A0A0B5FJZ2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

483547:GSUB RS11020
gene id: 483547:GSUB_RS11020
uniprot id: A0A0B5FTM4
names: Subcellular Location Annotation
messages: Cytoplasm

483547:GSUB RS08890
gene id: 483547:GSUB_RS08890
uniprot id: A0A0B5FES9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS09635
gene id: 483547:GSUB_RS09635
uniprot id: A0A0B5FT14
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

483547:GSUB RS09405
gene id: 483547:GSUB_RS09405
uniprot id: A0A0B5FSX8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

483547:GSUB RS11670
gene id: 483547:GSUB_RS11670
uniprot id: A0A0B5FG36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

483547:GSUB RS07235
gene id: 483547:GSUB_RS07235
uniprot id: A0A0B5FTF2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

483547:GSUB RS12575
gene id: 483547:GSUB_RS12575
uniprot id: A0A0B5FSU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

483547:GSUB RS05760
gene id: 483547:GSUB_RS05760
uniprot id: A0A0B5FDF1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

483547:GSUB RS13610
gene id: 483547:GSUB_RS13610
uniprot id: A0A0B5FRW0
names: Similarity
messages: Belongs to the UPF0502 family.

483547:GSUB RS01425
gene id: 483547:GSUB_RS01425
uniprot id: A0A0B5FPH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

483547:GSUB RS07695
gene id: 483547:GSUB_RS07695
uniprot id: A0A0B5FQR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

483547:GSUB RS02130
gene id: 483547:GSUB_RS02130
uniprot id: A0A0B5FE95
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

483547:GSUB RS01790
gene id: 483547:GSUB_RS01790
uniprot id: A0A0B5FNJ2
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS07785
gene id: 483547:GSUB_RS07785
uniprot id: A0A0B5FQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

483547:GSUB RS09175
gene id: 483547:GSUB_RS09175
uniprot id: A0A0B5FPU1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS05915
gene id: 483547:GSUB_RS05915
uniprot id: A0A0B5FFT5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS12080
gene id: 483547:GSUB_RS12080
uniprot id: A0A0B5FU85
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

483547:GSUB RS04815
gene id: 483547:GSUB_RS04815
uniprot id: A0A0B5FPM6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

483547:GSUB RS09190
gene id: 483547:GSUB_RS09190
uniprot id: A0A0B5FEW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

483547:GSUB RS10780
gene id: 483547:GSUB_RS10780
uniprot id: A0A0B5FHU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

483547:GSUB RS05110
gene id: 483547:GSUB_RS05110
uniprot id: A0A0B5FR82
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

483547:GSUB RS00270
gene id: 483547:GSUB_RS00270
uniprot id: A0A0B5FAY2
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS07715
gene id: 483547:GSUB_RS07715
uniprot id: A0A0B5FP81
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

483547:GSUB RS04410
gene id: 483547:GSUB_RS04410
uniprot id: A0A0B5FPD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

483547:GSUB RS15790
gene id: 483547:GSUB_RS15790
uniprot id: A0A0B5FHQ5
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

483547:GSUB RS15780
gene id: 483547:GSUB_RS15780
uniprot id: A0A0B5FU66
names: Similarity
messages: Belongs to the UPF0234 family.

483547:GSUB RS16385
gene id: 483547:GSUB_RS16385
uniprot id: A0A0B5FT27
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

483547:GSUB RS01720
gene id: 483547:GSUB_RS01720
uniprot id: A0A0B5FBM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

483547:GSUB RS06150
gene id: 483547:GSUB_RS06150
uniprot id: A0A0B5FIA4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

483547:GSUB RS10930
gene id: 483547:GSUB_RS10930
uniprot id: A0A0B5FS50
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS16545
gene id: 483547:GSUB_RS16545
uniprot id: A0A0B5FTV5
names: Similarity
messages: Belongs to the GSP E family.

483547:GSUB RS02730
gene id: 483547:GSUB_RS02730
uniprot id: A0A0B5FQ27
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS15645
gene id: 483547:GSUB_RS15645
uniprot id: A0A0B5FHN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

483547:GSUB RS01490
gene id: 483547:GSUB_RS01490
uniprot id: A0A0B5FE06
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

483547:GSUB RS17570
gene id: 483547:GSUB_RS17570
uniprot id: A0A0B5FVW8
names: Similarity
messages: Belongs to the ParB family.

483547:GSUB RS10905
gene id: 483547:GSUB_RS10905
uniprot id: A0A0B5FS45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

483547:GSUB RS13295
gene id: 483547:GSUB_RS13295
uniprot id: A0A0B5FIZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

483547:GSUB RS12605
gene id: 483547:GSUB_RS12605
uniprot id: A0A0B5FSU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

483547:GSUB RS00835
gene id: 483547:GSUB_RS00835
uniprot id: A0A0B5FB80
names: Subunit
messages: Homodimer.

483547:GSUB RS00825
gene id: 483547:GSUB_RS00825
uniprot id: A0A0B5FN48
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

483547:GSUB RS05625
gene id: 483547:GSUB_RS05625
uniprot id: A0A0B5FFQ6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

483547:GSUB RS11465
gene id: 483547:GSUB_RS11465
uniprot id: A0A0B5FTY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

483547:GSUB RS09160
gene id: 483547:GSUB_RS09160
uniprot id: A0A0B5FSV0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

483547:GSUB RS12480
gene id: 483547:GSUB_RS12480
uniprot id: A0A0B5FGE3
names: Similarity
messages: Belongs to the TrpF family.

483547:GSUB RS01495
gene id: 483547:GSUB_RS01495
uniprot id: A0A0B5FLJ1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

483547:GSUB RS12490
gene id: 483547:GSUB_RS12490
uniprot id: A0A0B5FRD7
names: Similarity
messages: Belongs to the TrpC family.

483547:GSUB RS14455
gene id: 483547:GSUB_RS14455
uniprot id: A0A0B5FH61
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

483547:GSUB RS11695
gene id: 483547:GSUB_RS11695
uniprot id: A0A0B5FU20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

483547:GSUB RS05105
gene id: 483547:GSUB_RS05105
uniprot id: A0A0B5FPU2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

483547:GSUB RS01555
gene id: 483547:GSUB_RS01555
uniprot id: A0A0B5FLM3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

483547:GSUB RS07075
gene id: 483547:GSUB_RS07075
uniprot id: A0A0B5FGA5
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS15330
gene id: 483547:GSUB_RS15330
uniprot id: A0A0B5FSL4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

483547:GSUB RS08910
gene id: 483547:GSUB_RS08910
uniprot id: A0A0B5FR94
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

483547:GSUB RS08320
gene id: 483547:GSUB_RS08320
uniprot id: A0A0B5FGV6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

483547:GSUB RS02645
gene id: 483547:GSUB_RS02645
uniprot id: A0A0B5FBY1
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

483547:GSUB RS12880
gene id: 483547:GSUB_RS12880
uniprot id: A0A0B5FRK1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS00110
gene id: 483547:GSUB_RS00110
uniprot id: A0A0B5FNV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

483547:GSUB RS08030
gene id: 483547:GSUB_RS08030
uniprot id: A0A0B5FPD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS13485
gene id: 483547:GSUB_RS13485
uniprot id: A0A0B5FUS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

483547:GSUB RS13040
gene id: 483547:GSUB_RS13040
uniprot id: A0A0B5FIW0
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS12955
gene id: 483547:GSUB_RS12955
uniprot id: A0A0B5FRL2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

483547:GSUB RS11375
gene id: 483547:GSUB_RS11375
uniprot id: A0A0B5FQZ8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

483547:GSUB RS09620
gene id: 483547:GSUB_RS09620
uniprot id: A0A0B5FH88
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

483547:GSUB RS06190
gene id: 483547:GSUB_RS06190
uniprot id: A0A0B5FFW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

483547:GSUB RS06445
gene id: 483547:GSUB_RS06445
uniprot id: A0A0B5FNP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

483547:GSUB RS07520
gene id: 483547:GSUB_RS07520
uniprot id: A0A0B5FE36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

483547:GSUB RS09020
gene id: 483547:GSUB_RS09020
uniprot id: A0A0B5FSS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS13115
gene id: 483547:GSUB_RS13115
uniprot id: A0A0B5FIX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

483547:GSUB RS02725
gene id: 483547:GSUB_RS02725
uniprot id: A0A0B5FNS9
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS10315
gene id: 483547:GSUB_RS10315
uniprot id: A0A0B5FTC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

483547:GSUB RS04325
gene id: 483547:GSUB_RS04325
uniprot id: A0A0B5FQS1
names: Similarity
messages: Belongs to the UPF0178 family.

483547:GSUB RS07015
gene id: 483547:GSUB_RS07015
uniprot id: A0A0B5FDV7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

483547:GSUB RS13290
gene id: 483547:GSUB_RS13290
uniprot id: A0A0B5FGP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

483547:GSUB RS09165
gene id: 483547:GSUB_RS09165
uniprot id: A0A0B5FEW0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS10655
gene id: 483547:GSUB_RS10655
uniprot id: A0A0B5FFJ9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

483547:GSUB RS00415
gene id: 483547:GSUB_RS00415
uniprot id: A0A0B5FP04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

483547:GSUB RS00655
gene id: 483547:GSUB_RS00655
uniprot id: A0A0B5FB50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

483547:GSUB RS10430
gene id: 483547:GSUB_RS10430
uniprot id: A0A0B5FHP3
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

483547:GSUB RS05125
gene id: 483547:GSUB_RS05125
uniprot id: A0A0B5FNA7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

483547:GSUB RS11380
gene id: 483547:GSUB_RS11380
uniprot id: A0A0B5FSE2
names: Similarity
messages: Belongs to the cytochrome c-552 family.

483547:GSUB RS11410
gene id: 483547:GSUB_RS11410
uniprot id: A0A0B5FTY3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

483547:GSUB RS08825
gene id: 483547:GSUB_RS08825
uniprot id: A0A0B5FGZ3
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS02420
gene id: 483547:GSUB_RS02420
uniprot id: A0A0B5FEC6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

483547:GSUB RS13260
gene id: 483547:GSUB_RS13260
uniprot id: A0A0B5FRR1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

483547:GSUB RS03015
gene id: 483547:GSUB_RS03015
uniprot id: A0A0B5FC44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

483547:GSUB RS10365
gene id: 483547:GSUB_RS10365
uniprot id: A0A0B5FFF3
names: Similarity
messages: Belongs to the NodU/CmcH family.

483547:GSUB RS03240
gene id: 483547:GSUB_RS03240
uniprot id: A0A0B5FMA3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

483547:GSUB RS09285
gene id: 483547:GSUB_RS09285
uniprot id: A0A0B5FH44
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

483547:GSUB RS05300
gene id: 483547:GSUB_RS05300
uniprot id: A0A0B5FFM9
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS03815
gene id: 483547:GSUB_RS03815
uniprot id: A0A0B5FCF7
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

483547:GSUB RS07090
gene id: 483547:GSUB_RS07090
uniprot id: A0A0B5FQI3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

483547:GSUB RS00665
gene id: 483547:GSUB_RS00665
uniprot id: A0A0B5FL56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

483547:GSUB RS00700
gene id: 483547:GSUB_RS00700
uniprot id: A0A0B5FP73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

483547:GSUB RS03740
gene id: 483547:GSUB_RS03740
uniprot id: A0A0B5FQI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

483547:GSUB RS14840
gene id: 483547:GSUB_RS14840
uniprot id: A0A0B5FSE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

483547:GSUB RS09415
gene id: 483547:GSUB_RS09415
uniprot id: A0A0B5FH64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

483547:GSUB RS00490
gene id: 483547:GSUB_RS00490
uniprot id: A0A0B5FN01
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

483547:GSUB RS16045
gene id: 483547:GSUB_RS16045
uniprot id: A0A0B5FSY1
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

483547:GSUB RS06895
gene id: 483547:GSUB_RS06895
uniprot id: A0A0B5FNU3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

483547:GSUB RS15030
gene id: 483547:GSUB_RS15030
uniprot id: A0A0B5FTT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

483547:GSUB RS00035
gene id: 483547:GSUB_RS00035
uniprot id: A0A0B5FAV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

483547:GSUB RS06805
gene id: 483547:GSUB_RS06805
uniprot id: A0A0B5FUT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

483547:GSUB RS06360
gene id: 483547:GSUB_RS06360
uniprot id: A0A0B5FFZ6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

483547:GSUB RS14170
gene id: 483547:GSUB_RS14170
uniprot id: A0A0B5FH33
names: Similarity
messages: Belongs to the HypD family.

483547:GSUB RS06790
gene id: 483547:GSUB_RS06790
uniprot id: A0A0B5FQD9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

483547:GSUB RS11120
gene id: 483547:GSUB_RS11120
uniprot id: A0A0B5FFU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

483547:GSUB RS00510
gene id: 483547:GSUB_RS00510
uniprot id: A0A0B5FL27
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

483547:GSUB RS14255
gene id: 483547:GSUB_RS14255
uniprot id: A0A0B5FH43
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

483547:GSUB RS02515
gene id: 483547:GSUB_RS02515
uniprot id: A0A0B5FNQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS10855
gene id: 483547:GSUB_RS10855
uniprot id: A0A0B5FFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

483547:GSUB RS01825
gene id: 483547:GSUB_RS01825
uniprot id: A0A0B5FBN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

483547:GSUB RS07045
gene id: 483547:GSUB_RS07045
uniprot id: A0A0B5FG99
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

483547:GSUB RS04920
gene id: 483547:GSUB_RS04920
uniprot id: A0A0B5FN87
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

483547:GSUB RS12515
gene id: 483547:GSUB_RS12515
uniprot id: A0A0B5FIM5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

483547:GSUB RS05750
gene id: 483547:GSUB_RS05750
uniprot id: A0A0B5FQ13
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS03665
gene id: 483547:GSUB_RS03665
uniprot id: A0A0B5FQG6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

483547:GSUB RS02705
gene id: 483547:GSUB_RS02705
uniprot id: A0A0B5FBZ2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

483547:GSUB RS09095
gene id: 483547:GSUB_RS09095
uniprot id: A0A0B5FPS6
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

483547:GSUB RS07400
gene id: 483547:GSUB_RS07400
uniprot id: A0A0B5FS37
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

483547:GSUB RS13825
gene id: 483547:GSUB_RS13825
uniprot id: A0A0B5FUY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

483547:GSUB RS00450
gene id: 483547:GSUB_RS00450
uniprot id: A0A0B5FDI0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

483547:GSUB RS09585
gene id: 483547:GSUB_RS09585
uniprot id: A0A0B5FF13
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

483547:GSUB RS07615
gene id: 483547:GSUB_RS07615
uniprot id: A0A0B5FE48
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

483547:GSUB RS03210
gene id: 483547:GSUB_RS03210
uniprot id: A0A0B5FQA4
names: Similarity
messages: Belongs to the universal stress protein A family.

483547:GSUB RS12980
gene id: 483547:GSUB_RS12980
uniprot id: A0A0B5FIU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

483547:GSUB RS00280
gene id: 483547:GSUB_RS00280
uniprot id: A0A0B5FKX9
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS04965
gene id: 483547:GSUB_RS04965
uniprot id: A0A0B5FD32
names: Similarity
messages: Belongs to the ribF family.

483547:GSUB RS08070
gene id: 483547:GSUB_RS08070
uniprot id: A0A0B5FQX7
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS07530
gene id: 483547:GSUB_RS07530
uniprot id: A0A0B5FGH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

483547:GSUB RS17005
gene id: 483547:GSUB_RS17005
uniprot id: A0A0B5FX61
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

483547:GSUB RS03905
gene id: 483547:GSUB_RS03905
uniprot id: A0A0B5FQK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

483547:GSUB RS01775
gene id: 483547:GSUB_RS01775
uniprot id: A0A0B5FLQ0
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS14190
gene id: 483547:GSUB_RS14190
uniprot id: A0A0B5FTH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

483547:GSUB RS01730
gene id: 483547:GSUB_RS01730
uniprot id: A0A0B5FE55
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

483547:GSUB RS09575
gene id: 483547:GSUB_RS09575
uniprot id: A0A0B5FRH8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

483547:GSUB RS04625
gene id: 483547:GSUB_RS04625
uniprot id: A0A0B5FQW8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

483547:GSUB RS11100
gene id: 483547:GSUB_RS11100
uniprot id: A0A0B5FI08
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS05170
gene id: 483547:GSUB_RS05170
uniprot id: A0A0B5FPU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

483547:GSUB RS14470
gene id: 483547:GSUB_RS14470
uniprot id: A0A0B5FTL9
names: Similarity
messages: Belongs to the GSP E family.

483547:GSUB RS04980
gene id: 483547:GSUB_RS04980
uniprot id: A0A0B5FN91
names: Similarity
messages: Belongs to the GSP E family.

483547:GSUB RS04355
gene id: 483547:GSUB_RS04355
uniprot id: A0A0B5FCP5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

483547:GSUB RS10320
gene id: 483547:GSUB_RS10320
uniprot id: A0A0B5FFE9
names: Similarity
messages: Belongs to the YicC/YloC family.

483547:GSUB RS02190
gene id: 483547:GSUB_RS02190
uniprot id: A0A0B5FBS3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

483547:GSUB RS15775
gene id: 483547:GSUB_RS15775
uniprot id: A0A0B5FST7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

483547:GSUB RS05605
gene id: 483547:GSUB_RS05605
uniprot id: A0A0B5FNF2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

483547:GSUB RS03405
gene id: 483547:GSUB_RS03405
uniprot id: A0A0B5FP13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

483547:GSUB RS09025
gene id: 483547:GSUB_RS09025
uniprot id: A0A0B5FEU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS13625
gene id: 483547:GSUB_RS13625
uniprot id: A0A0B5FUV2
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS12615
gene id: 483547:GSUB_RS12615
uniprot id: A0A0B5FGG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

483547:GSUB RS10775
gene id: 483547:GSUB_RS10775
uniprot id: A0A0B5FFM1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

483547:GSUB RS04290
gene id: 483547:GSUB_RS04290
uniprot id: A0A0B5FPB5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

483547:GSUB RS06470
gene id: 483547:GSUB_RS06470
uniprot id: A0A0B5FG16
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

483547:GSUB RS16550
gene id: 483547:GSUB_RS16550
uniprot id: A0A0B5FVB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

483547:GSUB RS00395
gene id: 483547:GSUB_RS00395
uniprot id: A0A0B5FB03
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS06280
gene id: 483547:GSUB_RS06280
uniprot id: A0A0B5FNM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

483547:GSUB RS12425
gene id: 483547:GSUB_RS12425
uniprot id: A0A0B5FUC0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

483547:GSUB RS01300
gene id: 483547:GSUB_RS01300
uniprot id: A0A0B5FLG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

483547:GSUB RS00425
gene id: 483547:GSUB_RS00425
uniprot id: A0A0B5FDH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

483547:GSUB RS00680
gene id: 483547:GSUB_RS00680
uniprot id: A0A0B5FB55
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

483547:GSUB RS15720
gene id: 483547:GSUB_RS15720
uniprot id: A0A0B5FSS8
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS10965
gene id: 483547:GSUB_RS10965
uniprot id: A0A0B5FFQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

483547:GSUB RS10450
gene id: 483547:GSUB_RS10450
uniprot id: A0A0B5FFG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

483547:GSUB RS06750
gene id: 483547:GSUB_RS06750
uniprot id: A0A0B5FNS6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

483547:GSUB RS04975
gene id: 483547:GSUB_RS04975
uniprot id: A0A0B5FFJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

483547:GSUB RS02560
gene id: 483547:GSUB_RS02560
uniprot id: A0A0B5FM12
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS10840
gene id: 483547:GSUB_RS10840
uniprot id: A0A0B5FQM9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

483547:GSUB RS12455
gene id: 483547:GSUB_RS12455
uniprot id: A0A0B5FGD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

483547:GSUB RS00465
gene id: 483547:GSUB_RS00465
uniprot id: A0A0B5FP17
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

483547:GSUB RS14545
gene id: 483547:GSUB_RS14545
uniprot id: A0A0B5FH73
names: Similarity
messages: Belongs to the DEAD box helicase family.

483547:GSUB RS03055
gene id: 483547:GSUB_RS03055
uniprot id: A0A0B5FEL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

483547:GSUB RS06155
gene id: 483547:GSUB_RS06155
uniprot id: A0A0B5FDI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

483547:GSUB RS04105
gene id: 483547:GSUB_RS04105
uniprot id: A0A0B5FMN1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

483547:GSUB RS00095
gene id: 483547:GSUB_RS00095
uniprot id: A0A0B5FKV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

483547:GSUB RS13670
gene id: 483547:GSUB_RS13670
uniprot id: A0A0B5FRX1
names: Subcellular Location Annotation
messages: Membrane

483547:GSUB RS13870
gene id: 483547:GSUB_RS13870
uniprot id: A0A0B5FJ93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

483547:GSUB RS12525
gene id: 483547:GSUB_RS12525
uniprot id: A0A0B5FST4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

483547:GSUB RS10660
gene id: 483547:GSUB_RS10660
uniprot id: A0A0B5FHS6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

483547:GSUB RS17315
gene id: 483547:GSUB_RS17315
uniprot id: A0A0B5FUB9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

483547:GSUB RS10030
gene id: 483547:GSUB_RS10030
uniprot id: A0A0B5FRP8
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

483547:GSUB RS03140
gene id: 483547:GSUB_RS03140
uniprot id: A0A0B5FEM2
names: Similarity
messages: Belongs to the LarC family.

483547:GSUB RS10915
gene id: 483547:GSUB_RS10915
uniprot id: A0A0B5FFP2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS02550
gene id: 483547:GSUB_RS02550
uniprot id: A0A0B5FBW6
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

483547:GSUB RS12230
gene id: 483547:GSUB_RS12230
uniprot id: A0A0B5FSP1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

483547:GSUB RS02185
gene id: 483547:GSUB_RS02185
uniprot id: A0A0B5FPU3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

483547:GSUB RS00625
gene id: 483547:GSUB_RS00625
uniprot id: A0A0B5FP54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

483547:GSUB RS13355
gene id: 483547:GSUB_RS13355
uniprot id: A0A0B5FJ16
names: Subcellular Location Annotation
messages: Membrane